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Technologies in Spine Surgery 脊柱外科技术
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.2021.10.487
M. Yildirim
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引用次数: 0
Computer-Assisted Surgery of the Spine 计算机辅助脊柱外科
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.2021.10.488
E. Sorantin
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引用次数: 0
Novel Total Nucleus Replacement Using Spherical Magnetic Beads: A Biomechanical Study 新型球形磁珠全核置换:生物力学研究
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.2021.10.479
Cristian Balcescu, Gurjiwan Dhaliwal, Roman P. Dimov, Nikole Chetty, Andrea Rowl, O. Raji, J. Leasure, Dimitriy G Kondrashov
Objective: Lumbar Degenerative Disc Disease is a potential cause of spinal instability. Surgical techniques such as arthrodesis or arthroplasty are implemented to restore the stability to the spine. Both a fusion and a disc replacement are substantially invasive. A lumbar disk replacement is typically done via retroperitoneal or Trans peritoneal approach. With increasing number of symptomatic levels, the disk replacement becomes incrementally more invasive, with a potential for a significant blood loss, injury to great vessels, injury to abdominal viscera, weakening of abdominal wall, etc. There is no minimally invasive way to perform a disk replacement either at one or multiple levels. Our goal was to evaluate the feasibility of a novel and less invasive total nucleus replacement using magnetic spherical beads in a cadaver-based multidirectional bending flexibility model. We aimed to assess the ability of the beads to restore stability to a spine segment. We hypothesized that the beads would increase stability during flexion and extension motions. Methods: Three fresh-frozen, human cadaveric L2-L3 segments were used. We performed multidirectional flexibility tests in six directions, under intact, nucleotomy and bead insertion conditions. We measured the ranges of motions, the neutral zone and the elastic zone. Results: There was statistically significantly more flexion-extension range of motion, neutral zone and elastic zone observed upon nucleotomy than during intact condition. Bead insertion statistically significantly reduced the neutral zone observed after nucleotomy, during flexion and extension loading. Conclusion: We conclude that our novel total nucleus replacement is capable of restoring the stability to spine motion segments during flexion and extension motions, by means of adjustments to their neutral zones.
目的:腰椎间盘退行性疾病是脊柱不稳定的潜在原因。手术技术,如关节融合术或关节成形术,以恢复脊柱的稳定性。融合和椎间盘置换术基本上都是侵入性的。腰椎间盘置换术通常通过腹膜后或经腹膜入路进行。随着症状水平的增加,椎间盘置换术的侵入性逐渐增强,有可能出现大量失血、大血管损伤、腹部脏器损伤、腹壁弱化等。没有微创的方法可以在一个或多个级别进行椎间盘置换术。我们的目标是在基于尸体的多向弯曲柔韧性模型中评估一种新颖且侵入性较小的磁球球全核置换的可行性。我们的目的是评估磁珠恢复脊柱节段稳定性的能力。我们假设这些珠子会增加屈伸运动时的稳定性。方法:采用新鲜冷冻的人尸体L2-L3节段。我们在六个方向上进行了多方向柔韧性测试,包括完整、核切开术和头部插入条件。我们测量了运动的范围,中性区和弹性区。结果:核切开术组屈伸活动度、中性区和弹性区均明显大于核切开术组。在屈曲和伸展负荷期间,核切开术后观察到的中性区明显减少。结论:我们的结论是,我们的新型全核置换术能够在屈伸运动中恢复脊柱运动节段的稳定性,通过调整其中性区。
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引用次数: 0
Spondylolisthesis at L4/5 but Fixation of L4, L5 and S1 Reduces the Rate of Adjacent Segment Degeneration L4/5椎体滑脱,但L4、L5和S1的固定可降低相邻节段退变率
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.2021.10.490
A. Islam, Shohidullah, Sarwar Rahman, Wayez Mahbub
Study background: Adjacent segment disease (ASD) is a common phenomenon seen in patients who have undergone prior lumbar fusion surgery is characterized by degeneration and/or stenosis. Treatment for ASD includes extension of the fusion with a posterior approach, with direct decompression of the neural elements when indicated. Methods: 54 patients of spondylolisthesis involving L4/5 level were included in this study that were operated from January 2012 to December 2020 in Bangabandhu Sheikh Mujib Medical University and few private hospital in Dhaka who failed to respond in conservative treatment. 30 patients were male and 24 were female. patients were evaluated by clinical finding (low back pain, sensory, motor and jerks) VAS score, ODI score, JOA score, modified Macnab’s criteria, claudication distance, X-ray lumbosacral spine AP and lateral view, MRI of lumbosacral spine, CT scan of lumbosacral spine. P value of less than 0.05 was level significance. Results: Mean (± SD) age of the patients was 56.29 ± 8.13 with highest age being 68 years and lowest being 41 years. 40 were male and 24 were female. Preoperative VAS score (for both back pain and leg pain) was 6.86 ± 0.65 which significantly reduced to 1.04 ± 0.19 36 months after operation. Out of 64 patients, 62 patients showed interbody fusion with good trabecular marking. Postoperative MRI of lumbosacral spine at 36 months showed 48 patients out of 64 had no desiccation of L3/4 disc, 9 had mild disc desiccation and 7 developed desiccation of L3/4 disc. Final outcome was determined by Modified Macnab’s criteria. Excellent result found in 39 patients, good result found in 22 patients and fair result found in 3 patients. Conclusion: Fixation of L4, L5 along with S1 in single level PLIF or TLIF in L4/5 level significantly reduce the rate of disc degeneration at L5/S1 level with slight degeneration at L3/4 level.
研究背景:邻段疾病(ASD)是一种常见的现象,见于既往行腰椎融合手术的患者,其特征为退变和/或狭窄。ASD的治疗包括后路扩大融合术,如有需要可直接减压神经元件。方法:选取2012年1月至2020年12月在孟加拉谢赫穆吉布医科大学及达卡少数私立医院手术的54例L4/5节段腰椎滑脱患者,经保守治疗无效。男性30例,女性24例。通过临床表现(腰痛、感觉、运动、抽搐)、VAS评分、ODI评分、JOA评分、改良Macnab标准、跛行距离、腰骶椎x线正位和侧位、腰骶椎MRI、腰骶椎CT扫描进行评价。P值小于0.05为水平显著性。结果:患者平均年龄(±SD)为56.29±8.13岁,最高年龄68岁,最低年龄41岁。其中男性40人,女性24人。术前VAS评分(腰痛和腿痛)为6.86±0.65,术后36个月VAS评分为1.04±0.19。在64例患者中,62例患者表现为体间融合,小梁标记良好。术后36个月腰骶椎MRI显示64例患者中48例无L3/4椎间盘干燥,9例轻度椎间盘干燥,7例发生L3/4椎间盘干燥。最终结果由Modified Macnab标准决定。优良者39例,良者22例,一般者3例。结论:L4、L5与S1单节段PLIF或L4/5节段TLIF固定可显著降低L5/S1节段椎间盘退变率,L3/4节段退变轻微。
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引用次数: 0
Importance of the Spine Intervention 脊柱干预的重要性
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.2021.10.491
Adrienne Clermont
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引用次数: 0
Editorial Note on Spondylolysis & Spondylolisthesis 关于峡部裂和峡部滑脱的社论注释
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.2021.10.473
P. Jha
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引用次数: 0
Elective Spine Surgery Preoperative Procedure 择期脊柱外科术前程序
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.2021.10.480
Rory Amne
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引用次数: 0
Unseen Bifid Spine at Preanaesthetic Discussion 麻醉前讨论看不见的两裂脊柱
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.21.10.4947
Skulpan Asavasopon
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引用次数: 0
Osteoporosis Importance of Convenient the Treatment Breaks 骨质疏松症的重要性,方便治疗中断
Pub Date : 2021-01-01 DOI: 10.37421/2165-7939.2021.10.500
G. González
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引用次数: 0
Bone Homeostasis Editorial 骨稳态编辑
Pub Date : 2021-01-01 DOI: 10.37421/JSP.2021.10.465
K. Mano
Editorial The elements of bone(s) are (I) mechanical help of delicate tissues, (ii) switches for muscle activity, (iii) security of the focal sensory system, (iv) arrival of calcium and different particles for the upkeep of a consistent ionic climate in the extracellular liquid, and (v) lodging and backing of hemopoiesis. The design and measure of bone, both at the plainly visible and minute level, are dictated by the hereditary outline and by administrative components that assist convey with trip bone capacities. Hereditary data is liable for the profoundly preserved anatomical state of bones and doubtlessly for reestablishing that shape after break. To achieve its capacities, bone goes through persistent decimation, called resorption, completed by osteoclasts, and development by osteoblasts. In the grown-up skeleton, the two cycles are in equilibrium, keeping a steady, homeostatically controlled measure of bone. This reality, just as the histological perception that osteoclastic bone resorption is trailed by osteoblastic bone development, prompted the idea that the two cycles are unthinkingly "coupled" and to the quest for "coupling factors." No single factor has been demonstrated to connect the two cycles. Existing proof recommends that various factors presumably are engaged with the upkeep of bone homeostasis. Development factors found in bone, for example, IGFs or TGFβs, were proposed to be delivered during resorption and start neighborhood bone arrangement. Elements saved on the bone surface by osteoclasts toward the finish of the resorption stage were proposed to start the bone development that follows. Humoral components, for example, parathyroid chemical and prostaglandin E, that animate both bone resorption and bone development, could expand the two cycles couple. The activity of these components and different chemicals and cytokines on osteoclasts was proposed to be interceded by osteoblast-genealogy
骨(s)的元素是(I)精细组织的机械帮助,(ii)肌肉活动的开关,(iii)焦点感觉系统的安全性,(iv)钙和不同颗粒的到达,以维持细胞外液体中一致的离子气候,以及(v)造血的寄主和支持。骨的设计和尺寸,无论是在明显可见的还是微小的水平上,都是由遗传轮廓和辅助传达旅行骨容量的管理组件决定的。遗传数据对骨骼保存完好的解剖状态负有责任,毫无疑问对骨折后的形状重建负有责任。为了实现它的功能,骨经历了持续的破坏,称为再吸收,由破骨细胞完成,并由成骨细胞发育。在成熟的骨骼中,这两个循环处于平衡状态,保持着稳定的、自我平衡控制的骨骼测量。这一事实,正如组织学上认为破骨细胞骨吸收落后于成骨细胞骨发育一样,促使人们认为这两个周期是不假思索地“耦合”的,并促使人们寻求“耦合因素”。没有一个单一的因素被证明将这两个周期联系起来。现有证据表明,可能有多种因素参与了骨骼稳态的维持。在骨中发现的发育因子,如igf或TGFβs,被认为在吸收过程中被递送,并开始邻近骨排列。在骨吸收阶段结束时,破骨细胞保存在骨表面的元素被认为可以开始随后的骨发育。体液成分,例如甲状旁腺化学物质和前列腺素E,促进骨吸收和骨发育,可以扩大这两个循环。这些成分和不同的化学物质和细胞因子对破骨细胞的活性被认为是通过成骨细胞谱系来调解的
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引用次数: 0
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Journal of spine
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