In many settings, a follow-up clinic visit two weeks after early medical abortion (EMA) is scheduled for a routine ultrasound to confirm that the pregnancy had been terminated. However, ultrasound facilities and the necessary manpower are costly and limit the settings where follow up can be provided.
{"title":"Follow up after early medical abortion: less is more","authors":"S. Cameron","doi":"10.1111/1471-0528.15940","DOIUrl":"https://doi.org/10.1111/1471-0528.15940","url":null,"abstract":"In many settings, a follow-up clinic visit two weeks after early medical abortion (EMA) is scheduled for a routine ultrasound to confirm that the pregnancy had been terminated. However, ultrasound facilities and the necessary manpower are costly and limit the settings where follow up can be provided.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87022249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The first step in preventing preterm birth (PTB) is screening for risk factors and then assessing risk accurately. One of the most important risk factors is a history of spontaneous PTB or PPROM <34 weeks or late miscarriage. Considerable efforts have been made in recent years to identify tests predictive for spontaneous PTB in this high risk population. Cervical length, measured by transvaginal ultrasonography, and quantitative cervicovaginal fetal fibronectin concentrations are currently the best predictive markers for spontaneous PTB in asymptomatic women, mainly because of their high negative predictive values (Honest H et al, Health Technol Assess 2009;13:1-627). This article is protected by copyright. All rights reserved.
{"title":"Preventing preterm birth: ‘do good or at least do no harm’","authors":"P. Rozenberg","doi":"10.1111/1471-0528.15931","DOIUrl":"https://doi.org/10.1111/1471-0528.15931","url":null,"abstract":"The first step in preventing preterm birth (PTB) is screening for risk factors and then assessing risk accurately. One of the most important risk factors is a history of spontaneous PTB or PPROM <34 weeks or late miscarriage. Considerable efforts have been made in recent years to identify tests predictive for spontaneous PTB in this high risk population. Cervical length, measured by transvaginal ultrasonography, and quantitative cervicovaginal fetal fibronectin concentrations are currently the best predictive markers for spontaneous PTB in asymptomatic women, mainly because of their high negative predictive values (Honest H et al, Health Technol Assess 2009;13:1-627). This article is protected by copyright. All rights reserved.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88420216","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
C. Cluver, Weslin Charles, Christina van der Merwe, Heidre Bezuidenhout, Daan Nel, C. Groenewald, Lucy Brink, S. Hesselman, Lina Bergman, Hein J. Odendaal
To examine the association of prenatal alcohol exposure (PAE) on cognitive abilities and behaviour profiles of 4‐year‐old children.
研究产前酒精暴露(PAE)与4岁儿童认知能力和行为特征的关系。
{"title":"The association of prenatal alcohol exposure on the cognitive abilities and behaviour profiles of 4‐year‐old children: a prospective cohort study","authors":"C. Cluver, Weslin Charles, Christina van der Merwe, Heidre Bezuidenhout, Daan Nel, C. Groenewald, Lucy Brink, S. Hesselman, Lina Bergman, Hein J. Odendaal","doi":"10.1111/1471-0528.15947","DOIUrl":"https://doi.org/10.1111/1471-0528.15947","url":null,"abstract":"To examine the association of prenatal alcohol exposure (PAE) on cognitive abilities and behaviour profiles of 4‐year‐old children.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86486022","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Oral fluconazole is used to treat vulvovaginal candidiasis during pregnancy. However, there are concerns regarding the pregnancy outcomes following exposure to fluconazole.
口服氟康唑用于治疗妊娠期间外阴阴道念珠菌病。然而，对氟康唑暴露后的妊娠结局存在担忧。
{"title":"The safety of oral fluconazole during the first trimester of pregnancy: a systematic review and meta‐analysis","authors":"Zhe Zhang, Xue Zhang, Yuan‐yue Zhou, Chun-Ming Jiang, Hai-yin Jiang","doi":"10.1111/1471-0528.15913","DOIUrl":"https://doi.org/10.1111/1471-0528.15913","url":null,"abstract":"Oral fluconazole is used to treat vulvovaginal candidiasis during pregnancy. However, there are concerns regarding the pregnancy outcomes following exposure to fluconazole.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79039638","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"BJOG Referees 2018","authors":"","doi":"10.1111/1471-0528.15966","DOIUrl":"https://doi.org/10.1111/1471-0528.15966","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81183187","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
L. Marcellin, M. Leconte, S. Gaujoux, P. Santulli, B. Borghese, C. Chapron, B. Dousset
To determine whether ileocaecal endometriosis (ICE) is a marker for low rectal endometriosis (LRE) severity.
目的:确定回盲子宫内膜异位症(ICE)是否为低位直肠子宫内膜异位症(LRE)严重程度的标志。
{"title":"Associated ileocaecal location is a marker for greater severity of low rectal endometriosis","authors":"L. Marcellin, M. Leconte, S. Gaujoux, P. Santulli, B. Borghese, C. Chapron, B. Dousset","doi":"10.1111/1471-0528.15901","DOIUrl":"https://doi.org/10.1111/1471-0528.15901","url":null,"abstract":"To determine whether ileocaecal endometriosis (ICE) is a marker for low rectal endometriosis (LRE) severity.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"76103047","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The world of obstetrics is often portrayed with a cinematic quality – the romance of pregnancy poised against the possibility of sheer loss. As a fourth-year medical student, I was excited but anxious about what this new rotation would have in store. To better prepare us for the obstetric emergencies we could encounter later in life, we participated in a simulation workshop with an emphasis on postpartum haemorrhage. Our task was simple – to assume a role in the treating team and collaborate, against the clock, to stabilise our simulated mother.
{"title":"Just like the real thing…","authors":"Mark P. Ranasinghe, Arunaz Kumar","doi":"10.1111/1471-0528.15924","DOIUrl":"https://doi.org/10.1111/1471-0528.15924","url":null,"abstract":"The world of obstetrics is often portrayed with a cinematic quality – the romance of pregnancy poised against the possibility of sheer loss. As a fourth-year medical student, I was excited but anxious about what this new rotation would have in store. To better prepare us for the obstetric emergencies we could encounter later in life, we participated in a simulation workshop with an emphasis on postpartum haemorrhage. Our task was simple – to assume a role in the treating team and collaborate, against the clock, to stabilise our simulated mother.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82311961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Sir, We entirely agree with Watson et al. that QUiPP provides an important contribution to the concept of individualised risk assessment and shared decisionmaking in the context of preterm birth prevention. We also agree that QUiPP, like cervical length measurements, may play a role in reassurance and targeting of interventions. However, we should also be open to a possibility that ‘false reassurance’may lead to (lack of) actions that may cause harm to individuals. We hypothesised that by applying fixed QUiPP risk thresholds, our current treatment strategies could be improved with a reduction in the false reassurance provided by long cervical length alone, so enhancing, rather than undermining, the QUiPP value. We are, therefore, pleased that peer-reviewers and Editors agreed with us that there is a merit in examining possible consequences of performing QUiPP analysis in the asymptomatic population at between 18 and 22 weeks of gestation in women with a previous preterm birth, who are often psychologically vulnerable. We completely agree with Watson et al. that the QUiPP app’s proven predictive performance ought not be dismissed, far from it. Our results should encourage other groups to publish the impact of individualised risk assessment on their clinical decisionmaking throughout pregnancy and on important clinical outcomes.& References
{"title":"Authors’ reply re: Effect of QUiPP prediction algorithm on treatment decisions in women with a previous preterm birth: a prospective cohort study","authors":"L. Goodfellow, Z. Alfirevic","doi":"10.1111/1471-0528.15944","DOIUrl":"https://doi.org/10.1111/1471-0528.15944","url":null,"abstract":"Sir, We entirely agree with Watson et al. that QUiPP provides an important contribution to the concept of individualised risk assessment and shared decisionmaking in the context of preterm birth prevention. We also agree that QUiPP, like cervical length measurements, may play a role in reassurance and targeting of interventions. However, we should also be open to a possibility that ‘false reassurance’may lead to (lack of) actions that may cause harm to individuals. We hypothesised that by applying fixed QUiPP risk thresholds, our current treatment strategies could be improved with a reduction in the false reassurance provided by long cervical length alone, so enhancing, rather than undermining, the QUiPP value. We are, therefore, pleased that peer-reviewers and Editors agreed with us that there is a merit in examining possible consequences of performing QUiPP analysis in the asymptomatic population at between 18 and 22 weeks of gestation in women with a previous preterm birth, who are often psychologically vulnerable. We completely agree with Watson et al. that the QUiPP app’s proven predictive performance ought not be dismissed, far from it. Our results should encourage other groups to publish the impact of individualised risk assessment on their clinical decisionmaking throughout pregnancy and on important clinical outcomes.& References","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75762168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
K. Dathe, J. Frank, S. Padberg, S. Hultzsch, K. Meixner, E. Beck, R. Meister, C. Schaefer
Risk of fetotoxicity after paracetamol exposure in the third trimester.
妊娠晚期接触扑热息痛后胎儿中毒的风险。
{"title":"Negligible risk of prenatal ductus arteriosus closure or fetal renal impairment after third‐trimester paracetamol use: evaluation of the German Embryotox cohort","authors":"K. Dathe, J. Frank, S. Padberg, S. Hultzsch, K. Meixner, E. Beck, R. Meister, C. Schaefer","doi":"10.1111/1471-0528.15872","DOIUrl":"https://doi.org/10.1111/1471-0528.15872","url":null,"abstract":"Risk of fetotoxicity after paracetamol exposure in the third trimester.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75544151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
HALIL TEKINER, DEPARTMENT OF MEDICAL HISTORY AND ETHICS, ERCIYES UNIVERSITY SCHOOL OF MEDICINE, KAYSERI, TURKEY, STEVEN YALE, DEPARTMENT OF INTERNAL MEDICINE, UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE, ORLANDO, FL, USA, AND REHAT FAIKOGLU, DEPARTMENT OF NURSING, ISTANBUL AREL UNIVERSITY SCHOOL OF HEALTH SCIENCES, ISTANBUL, TURKEY .......................................................................................................................................................................
{"title":"Surgical compression of uterus: an early description","authors":"H. Tekiner, S. Yale, Rehat Faikoğlu","doi":"10.1111/1471-0528.15929","DOIUrl":"https://doi.org/10.1111/1471-0528.15929","url":null,"abstract":"HALIL TEKINER, DEPARTMENT OF MEDICAL HISTORY AND ETHICS, ERCIYES UNIVERSITY SCHOOL OF MEDICINE, KAYSERI, TURKEY, STEVEN YALE, DEPARTMENT OF INTERNAL MEDICINE, UNIVERSITY OF CENTRAL FLORIDA COLLEGE OF MEDICINE, ORLANDO, FL, USA, AND REHAT FAIKOGLU, DEPARTMENT OF NURSING, ISTANBUL AREL UNIVERSITY SCHOOL OF HEALTH SCIENCES, ISTANBUL, TURKEY .......................................................................................................................................................................","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80354825","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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