Jane E Frawley,Wen-Qiang He,Lisa McCallum,Peter McIntyre,Andrew Hayen,Heather Gidding,Elizabeth Sullivan,Bette Liu
OBJECTIVEAdverse birth outcomes and the maternal severity of influenza in pregnancy are well documented but information on pertussis is limited.DESIGNPopulation-based linkage data were collected during 2001-2016.SETTINGNew South Wales, Australia.POPULATION OR SAMPLEA total of 1 453 037 singleton births.METHODSCox regression was used to estimate the associations between pertussis or influenza during pregnancy and birth outcomes with adjustment of covariates.MAIN OUTCOME MEASURESAdverse birth outcomes (preterm birth and low birth weight).RESULTSAmong 1 453 037 singleton births over 16 years, we identified pertussis in 925 (49; 5.3% hospitalised) and influenza in 2850 (1092; 38.3% hospitalised) women during pregnancy. Cases of pertussis were similarly distributed by trimester (32% 3rd) whereas 46% of influenza cases were in the 3rd trimester. Younger age, previous birth, and being overseas-born were associated with both pertussis and influenza, whereas identifying as Aboriginal or Torres Strait Islander, hypertension or diabetes before and during pregnancy, and a number of other factors were only associated with influenza. Both pertussis and influenza in pregnancy were associated with increased risk of preterm birth (pertussis: aHR = 1.30, 95% CI 1.01-1.68; influenza: aHR = 1.56, 95% CI 1.36-1.79) and these increased risks were greater when infections in the period within 2 weeks of birth were considered (pertussis: aHR = 2.36, 95% CI 1.26-4.41; influenza: aHR = 2.29, 95% CI 1.78-2.96).CONCLUSIONSMaternal pertussis and influenza infections close to the time of birth were associated with adverse birth outcomes. These findings highlight the benefits of vaccination during pregnancy.
{"title":"Birth Outcomes After Pertussis and Influenza Diagnosed in Pregnancy: A Retrospective, Population-Based Study.","authors":"Jane E Frawley,Wen-Qiang He,Lisa McCallum,Peter McIntyre,Andrew Hayen,Heather Gidding,Elizabeth Sullivan,Bette Liu","doi":"10.1111/1471-0528.17984","DOIUrl":"https://doi.org/10.1111/1471-0528.17984","url":null,"abstract":"OBJECTIVEAdverse birth outcomes and the maternal severity of influenza in pregnancy are well documented but information on pertussis is limited.DESIGNPopulation-based linkage data were collected during 2001-2016.SETTINGNew South Wales, Australia.POPULATION OR SAMPLEA total of 1 453 037 singleton births.METHODSCox regression was used to estimate the associations between pertussis or influenza during pregnancy and birth outcomes with adjustment of covariates.MAIN OUTCOME MEASURESAdverse birth outcomes (preterm birth and low birth weight).RESULTSAmong 1 453 037 singleton births over 16 years, we identified pertussis in 925 (49; 5.3% hospitalised) and influenza in 2850 (1092; 38.3% hospitalised) women during pregnancy. Cases of pertussis were similarly distributed by trimester (32% 3rd) whereas 46% of influenza cases were in the 3rd trimester. Younger age, previous birth, and being overseas-born were associated with both pertussis and influenza, whereas identifying as Aboriginal or Torres Strait Islander, hypertension or diabetes before and during pregnancy, and a number of other factors were only associated with influenza. Both pertussis and influenza in pregnancy were associated with increased risk of preterm birth (pertussis: aHR = 1.30, 95% CI 1.01-1.68; influenza: aHR = 1.56, 95% CI 1.36-1.79) and these increased risks were greater when infections in the period within 2 weeks of birth were considered (pertussis: aHR = 2.36, 95% CI 1.26-4.41; influenza: aHR = 2.29, 95% CI 1.78-2.96).CONCLUSIONSMaternal pertussis and influenza infections close to the time of birth were associated with adverse birth outcomes. These findings highlight the benefits of vaccination during pregnancy.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142449350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charlotte Wilson,Bethany Atkins,Richard Molyneux,Claire Storey,Hannah Blencowe
BACKGROUNDNinety-eight percent of neonatal deaths worldwide occur in low- and middle-income countries (LMICs), yet there is little bereavement care guidance available for these settings.OBJECTIVESTo explore parents', families' and healthcare professionals' experiences of care after neonatal death in healthcare facilities in LMICs.SEARCH STRATEGY AND SELECTION CRITERIAFour databases were searched for peer-reviewed literature, meeting the inclusion criteria of qualitative studies exploring the experiences of people who provided or received bereavement care following neonatal death in a LMIC healthcare setting.DATA COLLECTION AND ANALYSISData were collected by two independent reviewers, collated through line-by-line coding and then reciprocal and refutational translation, and analysed through Noblit and Hare's seven-step meta-ethnography approach to create first-, second- and third-order themes.MAIN RESULTSSeven first-order themes extracted from the literature included emotional responses, social relationships, staff and systems, religion, connecting with the baby, coping strategies and economic concerns. From these data, three third-order themes arose: The individual, the healthcare setting and the community/context.CONCLUSIONSOverarching themes in bereavement care shape grief responses and are often similar across geographical locations. Analysing these similarities allows a deeper understanding of the important elements of bereavement care and may be helpful to inform the creation of high-quality, bereavement care guidelines suitable for use in LMIC settings.
背景全世界 98% 的新生儿死亡发生在低收入和中等收入国家 (LMIC)，但几乎没有针对这些环境的丧亲护理指南。检索策略和筛选标准在四个数据库中检索了同行评审过的文献，这些文献均符合定性研究的纳入标准，这些定性研究探讨了在低收入国家医疗机构中新生儿死亡后提供或接受丧亲护理的人员的经历。数据收集与分析数据由两名独立审稿人收集，通过逐行编码进行整理，然后进行互译和反驳翻译，并通过 Noblit 和 Hare 的七步元民族志方法进行分析，以创建一阶、二阶和三阶主题。主要结果从文献中提取的七个一阶主题包括情绪反应、社会关系、员工和系统、宗教、与婴儿的联系、应对策略和经济问题。从这些数据中产生了三个三阶主题：结论丧亲护理的总体主题决定了悲伤的反应，而且在不同的地理位置往往具有相似性。对这些相似性进行分析可以加深对丧亲关怀重要因素的理解，并有助于制定适合低收入和中等收入国家环境的高质量丧亲关怀指南。
{"title":"Parents', Families', Communities' and Healthcare Professionals' Experiences of Care Following Neonatal Death in Healthcare Facilities in LMICs: A Systematic Review and Meta-Ethnography.","authors":"Charlotte Wilson,Bethany Atkins,Richard Molyneux,Claire Storey,Hannah Blencowe","doi":"10.1111/1471-0528.17982","DOIUrl":"https://doi.org/10.1111/1471-0528.17982","url":null,"abstract":"BACKGROUNDNinety-eight percent of neonatal deaths worldwide occur in low- and middle-income countries (LMICs), yet there is little bereavement care guidance available for these settings.OBJECTIVESTo explore parents', families' and healthcare professionals' experiences of care after neonatal death in healthcare facilities in LMICs.SEARCH STRATEGY AND SELECTION CRITERIAFour databases were searched for peer-reviewed literature, meeting the inclusion criteria of qualitative studies exploring the experiences of people who provided or received bereavement care following neonatal death in a LMIC healthcare setting.DATA COLLECTION AND ANALYSISData were collected by two independent reviewers, collated through line-by-line coding and then reciprocal and refutational translation, and analysed through Noblit and Hare's seven-step meta-ethnography approach to create first-, second- and third-order themes.MAIN RESULTSSeven first-order themes extracted from the literature included emotional responses, social relationships, staff and systems, religion, connecting with the baby, coping strategies and economic concerns. From these data, three third-order themes arose: The individual, the healthcare setting and the community/context.CONCLUSIONSOverarching themes in bereavement care shape grief responses and are often similar across geographical locations. Analysing these similarities allows a deeper understanding of the important elements of bereavement care and may be helpful to inform the creation of high-quality, bereavement care guidelines suitable for use in LMIC settings.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142449349","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Galit Levi Dunietz,Claudia Holzman,Xiru Lyu,Riva Tauman,Janet M Catov
OBJECTIVEMaternal lipid levels increase in normal pregnancies. Here, we examine whether pregnancies with the highest total cholesterol, low-density lipoprotein (LDL) or triglyceride levels or the lowest high-density lipoprotein (HDL) levels predict future dyslipidemia post-pregnancy.DESIGNLongitudinal cohort study.SETTINGFive communities in Michigan, USA.SAMPLEPregnant women (n = 649) with blood lipid levels measured at mid-pregnancy in the Pregnancy Outcomes and Community Health (POUCH) Study and at the POUCHmoms Study follow-up, 7-15 years later.METHODSMaternal mid-pregnancy lipid levels were defined as 'high' (upper quartile of triglycerides ≥ 216 mg/dL, LDL ≥ 145 mg/dL and total cholesterol ≥ 256 mg/dL) or 'low' (lower quartile, HDL < 58 mg/dL) using whole sample lipid distributions. At follow-up, dyslipidemia was classified by the clinical cutoffs of triglycerides and total cholesterol ≥ 200 mg/dL, LDL ≥ 130 mg/dL and HDL < 50 mg/dL. Weighted regression models estimated the risk of dyslipidemia at follow-up in relation to pregnancy lipid levels, adjusted for baseline confounders.MAIN OUTCOME MEASUREDyslipidemia later in life.RESULTSMid-pregnancy triglycerides, LDL, and total cholesterol levels at the upper quartile were associated with at least threefold increase in the risk of abnormal triglycerides, LDL and total cholesterol levels later in life. Women with low mid-pregnancy HDL levels had just over a twofold increased risk of abnormally low HDL levels at follow-up. These associations persisted following adjustment for covariates, i.e. demographics, lifestyle, and years of follow-up.CONCLUSIONSHigher mid-pregnancy LDL, total cholesterol and triglycerides and lower levels of HDL may signal future dyslipidemia risk and the need for closer lipid monitoring to ensure timely interventions that can attenuate cardiovascular disease risk.
{"title":"Maternal Lipids in Pregnancy and Later Life Dyslipidemia: The POUCHmoms Longitudinal Cohort Study.","authors":"Galit Levi Dunietz,Claudia Holzman,Xiru Lyu,Riva Tauman,Janet M Catov","doi":"10.1111/1471-0528.17975","DOIUrl":"https://doi.org/10.1111/1471-0528.17975","url":null,"abstract":"OBJECTIVEMaternal lipid levels increase in normal pregnancies. Here, we examine whether pregnancies with the highest total cholesterol, low-density lipoprotein (LDL) or triglyceride levels or the lowest high-density lipoprotein (HDL) levels predict future dyslipidemia post-pregnancy.DESIGNLongitudinal cohort study.SETTINGFive communities in Michigan, USA.SAMPLEPregnant women (n = 649) with blood lipid levels measured at mid-pregnancy in the Pregnancy Outcomes and Community Health (POUCH) Study and at the POUCHmoms Study follow-up, 7-15 years later.METHODSMaternal mid-pregnancy lipid levels were defined as 'high' (upper quartile of triglycerides ≥ 216 mg/dL, LDL ≥ 145 mg/dL and total cholesterol ≥ 256 mg/dL) or 'low' (lower quartile, HDL < 58 mg/dL) using whole sample lipid distributions. At follow-up, dyslipidemia was classified by the clinical cutoffs of triglycerides and total cholesterol ≥ 200 mg/dL, LDL ≥ 130 mg/dL and HDL < 50 mg/dL. Weighted regression models estimated the risk of dyslipidemia at follow-up in relation to pregnancy lipid levels, adjusted for baseline confounders.MAIN OUTCOME MEASUREDyslipidemia later in life.RESULTSMid-pregnancy triglycerides, LDL, and total cholesterol levels at the upper quartile were associated with at least threefold increase in the risk of abnormal triglycerides, LDL and total cholesterol levels later in life. Women with low mid-pregnancy HDL levels had just over a twofold increased risk of abnormally low HDL levels at follow-up. These associations persisted following adjustment for covariates, i.e. demographics, lifestyle, and years of follow-up.CONCLUSIONSHigher mid-pregnancy LDL, total cholesterol and triglycerides and lower levels of HDL may signal future dyslipidemia risk and the need for closer lipid monitoring to ensure timely interventions that can attenuate cardiovascular disease risk.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142385300","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kailee N. May, Alexandra L. Regens, Kenichi A. Tanaka, Amir L. Butt
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{"title":"Unpacking the Complex Relationship Between Postpartum Haemorrhage and Cardiovascular Disease","authors":"Kailee N. May, Alexandra L. Regens, Kenichi A. Tanaka, Amir L. Butt","doi":"10.1111/1471-0528.17970","DOIUrl":"https://doi.org/10.1111/1471-0528.17970","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142329995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Comment on Green Top Guideline No. 31: Investigating and Care in the Small-For-Gestational-Age and Growth Restricted Foetus","authors":"Ioannis Papastefanou, Kypros H. Nicolaides","doi":"10.1111/1471-0528.17972","DOIUrl":"https://doi.org/10.1111/1471-0528.17972","url":null,"abstract":"Click on the article title to read more.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142329996","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"PAX1/SOX1 DNA Methylation Versus Cytology and HPV16/18 Genotyping for the Triage of High-Risk HPV-Positive Women in Cervical Cancer Screening: Retrospective Analysis of Archival Samples","authors":"Karen K. L. Chan, Stephanie S. Liu, Lesley S. K. Lau, Siew Fei Ngu, Mandy M. Y. Chu, K. Y. Tse, Annie N. Y. Cheung, Hextan Y. S. Ngan","doi":"10.1111/1471-0528.17965","DOIUrl":"https://doi.org/10.1111/1471-0528.17965","url":null,"abstract":"To compare the performance of cytology, HPV16/18 genotyping and PAX1/SOX1 methylation for the triage of high-risk HPV-positive cervical samples.","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142325817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pregnancy Outcomes in Women With Vascular EDS Provide High Mortality Rates","authors":"Matthew Cauldwell","doi":"10.1111/1471-0528.17961","DOIUrl":"https://doi.org/10.1111/1471-0528.17961","url":null,"abstract":"<h2> Conflicts of Interest</h2>\u0000<p>The author declares no conflicts of interest.</p>","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142321863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Authors' reply","authors":"Kathrine Fodstad, Katariina Laine, Sari Räisänen","doi":"10.1111/1471-0528.17958","DOIUrl":"https://doi.org/10.1111/1471-0528.17958","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142276797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Management of IFH: Challenges in UK Training.","authors":"Junaid Rafi","doi":"10.1111/1471-0528.17962","DOIUrl":"https://doi.org/10.1111/1471-0528.17962","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Leslie L Shultz,Hisako Okada,Amir L Butt,Kaitlyn J Kulesus
{"title":"In Utero Aspirin Exposure and Child Neurocognitive Development: Causation Over Correlation.","authors":"Leslie L Shultz,Hisako Okada,Amir L Butt,Kaitlyn J Kulesus","doi":"10.1111/1471-0528.17964","DOIUrl":"https://doi.org/10.1111/1471-0528.17964","url":null,"abstract":"","PeriodicalId":8984,"journal":{"name":"BJOG: An International Journal of Obstetrics & Gynaecology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-09-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142273539","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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