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Journal of gastroenterology and hepatology research最新文献

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Study on treatment and nursing of elderly patients with gastric cancer complicated with diabetes 老年胃癌合并糖尿病患者的治疗与护理研究
Pub Date : 2022-01-01 DOI: 10.53388/ghr2022-06-054
Xiaoqing Zhang
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引用次数: 0
Research progress on the correlation between metabolic-associated fatty liver disease and metabolic diseases 代谢性脂肪肝与代谢性疾病相关性的研究进展
Pub Date : 2022-01-01 DOI: 10.53388/ghr2022-06-051
Chi Zhao-chun
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引用次数: 0
Risk of Human Exposure to the Intestinal Schistosome, Schistosoma mansoni, across Seasons along the Senegal River 塞内加尔河沿岸不同季节人类接触肠道血吸虫(曼氏血吸虫)的风险
Pub Date : 2021-12-31 DOI: 10.24966/ghr-2566/100038
R. Jr
Background: Schistosomiasis is an emerging disease associated with changes to the environment that have increased human contact rates with disease-causing parasites, flatworms that are released from freshwater snails. For example, schistosomiasis remains a major public health problem in Northern Senegal, where prevalence in schoolchildren often reaches 90%. Aim: This study focuses on the impact of seasonality on the risk of human exposure (RHE) to Schistosoma mansoni, defined as the total number of cercariae (the free-living life stage that infects humans) shed from all Biomphalaria pfeifferi snails collected at a site using standardized methods. We focus on RHE because it is rarely quantified and a recent study demonstrated that snails stop shedding cercariae when snail densities increase and thus per capita snail resources become limited [2], suggesting that densities of snails might not be directly proportional to RHE to schistosomes. Method: We sampled four water access points in three villages every other week during the early (Dry1) and later dry seasons (Dry2) and the rainy season, quantifying the abundance of infected and non-infected snail intermediate hosts, cercariae released per infected snail, and water chemistry. We used simple and multiple linear regressions to assess how seasonality and environmental parameters affect non-infected and infected snail abundance and RHE. Results: Although RHE was found across all seasons, the abundance of infected and non-infected snail intermediate hosts and cercariae, as well as prevalence (23.71%), were all highest in the rainy season. In the rainy season, RHE was positively associated with the density of snail hosts and their periphyton food resource. Conclusion: Although previous studies have examined the influence of seasonality on snail densities, few studies have explored the effects of seasonality on cercarial densities, which is the primary source of infection to humans. Our study demonstrates that cercarial densities are greater in the rainy season than in the early or late dry seasons. Given that cercarial densities directly pose risk of infection to humans, unlike non-infected or infected snails, these finding should help to inform decision making and schistosomiasis control efforts in West Africa.
背景:血吸虫病是一种新出现的疾病,与环境变化有关,环境变化增加了人类与淡水蜗牛释放的致病性寄生虫和扁形虫的接触率。例如,在塞内加尔北部,血吸虫病仍然是一个主要的公共卫生问题,那里的学童患病率往往达到90%。目的:本研究的重点是季节性对人类暴露于曼氏血吸虫(Schistosoma mansoni)风险(RHE)的影响,定义为使用标准化方法从一个地点收集的所有Biomphalaria pfeifferi蜗牛中脱落的尾蚴(感染人类的自由生活生命阶段)的总数。我们之所以关注RHE,是因为RHE很少被量化,最近的一项研究表明,当蜗牛密度增加时,蜗牛不再脱落尾蚴,因此人均蜗牛资源变得有限[2],这表明蜗牛密度可能与RHE与血吸虫的比例不成正比。方法:每隔一周在3个村的4个取水点取样,分别在旱季早期(Dry1)和旱季后期(Dry2)和雨季取样,量化感染和未感染蜗牛中间宿主的丰度、每只感染蜗牛释放的尾蚴数和水化学。我们使用简单和多元线性回归来评估季节性和环境参数如何影响未感染和感染的蜗牛丰度和RHE。结果:虽然RHE一年四季均有发生,但感染和未感染的蜗牛中间宿主和尾蚴的丰度和流行率均以雨季最高(23.71%)。在雨季,RHE与蜗牛寄主密度及其周围植物食物资源呈正相关。结论:虽然以往的研究考察了季节性对蜗牛密度的影响,但很少有研究探讨了季节性对人类感染的主要来源——尾蚴密度的影响。我们的研究表明,雨季的子宫颈密度高于旱季的早期或晚期。鉴于与未感染或感染的蜗牛不同,尾蚴密度直接对人类构成感染风险,这些发现应有助于为西非的决策和血吸虫病控制工作提供信息。
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引用次数: 1
Exfoliated Deciduous Teeth Pulp Stem Cells: Data on Experimental and Clinical Potential 脱落的乳牙髓干细胞:实验和临床潜力的数据
Pub Date : 2021-08-21 DOI: 10.17554/J.ISSN.2224-3992.2021.10.1023
M. Eşrefoğlu
The stem cells from human exfoliated deciduous teeth (SHED) are multipotent adult mesenchymal stem cells playing essential roles in tissue regeneration and tissue repair. This type of stem cells are able to differentiate into various cell types. Their regenerative ability can be applied in dentistry as well as in various fields of regenerative medicine. The results obtained from experimental trials are generally promising. However clinical trials are still missing because of various challanges. Herein, I focus on the data obtained from fundamental and clinical trials assessing the benefits of SHED on regeneration of tooth decays, wound healing, craniofascial abnormalities, and treatment of various neurological, cardiovascular, digestive and muscular diseases.
人脱落乳牙干细胞是一种多能成体间充质干细胞,在组织再生和组织修复中发挥着重要作用。这种类型的干细胞能够分化成各种细胞类型。它们的再生能力可以应用于牙科以及再生医学的各个领域。从实验试验中得到的结果总体上是有希望的。然而,由于各种挑战,临床试验仍然缺失。在此,我着重于从基础和临床试验中获得的数据,评估SHED在蛀牙再生、伤口愈合、颅筋膜异常以及治疗各种神经、心血管、消化和肌肉疾病方面的益处。
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引用次数: 1
The Impact of Pathological Changes in the Intestinal Microbiocenosis on the Appearance or Intensification of Negative Behavior in Children with ASD 肠道微生物病病理改变对ASD患儿不良行为出现或加剧的影响
Pub Date : 2021-06-30 DOI: 10.24966/ghr-2566/100032
A. Maximova
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引用次数: 1
Idiopathic Portal Hypertension in a Celiac Disease Patient: A Rare Association 乳糜泻患者的特发性门脉高压:一种罕见的关联
Pub Date : 2021-06-30 DOI: 10.24966/ghr-2566/100033
Y. Reddy
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引用次数: 0
Primary Intrahepatic Mixed Neuroendocrine–Non neuroendocrine Neoplasm (MiNEN)-Rare Solid Cystic Neoplasm of Liver 原发性肝内混合神经内分泌-非神经内分泌肿瘤(MiNEN)-罕见的肝脏实性囊性肿瘤
Pub Date : 2021-06-30 DOI: 10.24966/ghr-2566/100035
P. Nathani
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引用次数: 0
The Most Relevant Extraintestinal Manifestations of Inflammatory Bowel Disease: A Multidisciplinary Approach 炎症性肠病最相关的肠外表现:多学科方法
Pub Date : 2021-06-30 DOI: 10.24966/ghr-2566/100036
C. A. A. de Brito
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引用次数: 1
Research progress on the correlation between metabolic associated fatty liver disease and psoriasis 代谢性脂肪性肝病与银屑病相关性研究进展
Pub Date : 2021-01-01 DOI: 10.53388/ghr2021-12-042
Zhao-chun Chi
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引用次数: 0
Research progress in the imaging diagnosis of non-alcoholic fatty pancreas disease 非酒精性脂肪性胰腺疾病的影像学诊断研究进展
Pub Date : 2021-01-01 DOI: 10.53388/ghr2021-03-030
Zhao-chun Chi
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引用次数: 0
期刊
Journal of gastroenterology and hepatology research
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