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Pisa Syndrome and Neurosyphilis: A Case Report in Taiwan 比萨症候群与神经梅毒:台湾1例报告
Pub Date : 2017-11-09 DOI: 10.4172/2325-9701.1000282
M. Wu, Chih-Hsiang Chiu, C. Su, K. Y. Hsieh
Background: Pisa syndrome, defined as more than 10 degrees tonic lateral flexion in upright spine without any significant associated vertebral rotation resembled the leaning tower of Pisa, is considered to be related to neuroleptics. Unfamiliarity of this disease, many neuro- and orthopedic surgeons can lead to unnecessary diagnostic and interventions. Method: We report an extremely rare case of neurosyphillis presenting with PISA syndrome in order to assess the clinical presentation and treatment. Results: A 49-year-old man, who has neurosyphillis and psychotic disorder due to general medical condition, treated by valproic acid 500 mg twice and quetiapine 200 mg once daily for as an unchanged regimen for the past 1 year. Five days after treatment with clozapine for poor controlled psychosis, he was noted leaned to one side. Physical examinations revealed a severe right truncal shift associated with left cervical tilt. We discontinued all medication except adding an anticholinergic drug (2 mg biperiden twice daily). After 7 days, the deformity disappeared with normal body posture. His psychosis flared up and we rechallenged clozapine 25mg daily. He was noticed leaned to one side again. Conclusions: orthopedic and neurological surgeons visiting patients with abnormal postures of the trunk need to evaluate medications especially with neuropsychiatric disease. Even drugs with a minimum risk of extrapyramidal symptoms, such as clozapine, can cause Pisa syndrome in even short duration and low dosage.
背景:比萨综合征被定义为直立脊柱强直性侧屈超过10度,没有任何明显的相关脊椎旋转,类似于比萨斜塔,被认为与神经抑制剂有关。许多神经外科医生和整形外科医生对这种疾病不熟悉,可能会导致不必要的诊断和干预。方法:我们报告了一例极为罕见的以PISA综合征为表现的神经梅毒患者,以评估其临床表现和治疗。结果:一名49岁的男性,由于一般医疗状况而患有神经性小丘和精神病,在过去的一年中,他每天两次服用丙戊酸500 mg和喹硫平200 mg,作为一种不变的治疗方案。在氯氮平治疗精神病控制不佳五天后,他被发现向一侧倾斜。体格检查显示,右侧躯干移位严重,伴有左侧颈椎倾斜。我们停止了所有药物,除了添加抗胆碱能药物(每天两次,每次2 mg比培林)。术后7天,畸形消失,体位正常。他的精神病发作了,我们重新给他注射了每天25毫克的氯氮平。有人注意到他又向一侧倾斜。结论:骨科和神经外科医生需要评估药物治疗,尤其是神经精神疾病患者。即使是锥体外系症状风险最小的药物,如氯氮平,也可以在短时间和低剂量内引起比萨综合征。
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引用次数: 0
Esophageal Impingement from Anterior Cervical Osteophytes Associated with Cervical Spondylosis 颈椎病合并颈前路骨赘对食管的冲击
Pub Date : 2017-11-06 DOI: 10.4172/2325-9701.1000274
P. Issack
We present the case of a 50-year-old lady with progressive neck pain, cervical myelopathy and dysphagia. Cervical spine radiographs and MRI demonstrated a large anterior cervical osteophyte complex impinging on the esophagus as well as cervical stenosis. Surgical treatment with anterior resection of osteophytes and anterior cervical discectomy with fusion relieved the patient’s dysphagia and neck pain. While there are several reports in the literature documenting resection of anterior osteophytes for dysphagia, most of these cases are secondary to DISH and do not present with neurologic symptoms (radiculopathy or myelopathy). To our knowledge, this is the first case presented where the patient presented with both dysphagia and clinical myelopathy, and required both resection of anterior osteophytes and cervical discectomy with fusion.
我们报告一位50岁的女性,患有进行性颈部疼痛、颈脊髓病和吞咽困难。颈椎X线片和核磁共振成像显示一个巨大的颈前骨赘复合体撞击食道以及颈管狭窄。骨赘前切除术和颈椎前路椎间盘切除融合术的手术治疗缓解了患者的吞咽困难和颈部疼痛。虽然文献中有几篇报道记录了切除前骨赘治疗吞咽困难,但这些病例大多继发于DISH,不存在神经系统症状(神经根病或脊髓病)。据我们所知,这是第一例患者同时出现吞咽困难和临床脊髓病,需要切除前部骨赘和融合颈椎间盘切除术的病例。
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引用次数: 1
Remote Cauda Equina Syndrome Due to Overgrowth of Epidural Free Fat Graft: Case Report 硬膜外游离脂肪移植物过度生长所致远端马尾综合征1例
Pub Date : 2017-11-06 DOI: 10.4172/2325-9701.1000279
A. Rahimizadeh, A. Rahimizadeh, Valiolah Hassani, Shaghayegh Rahimizadeh
Lumbar discectomy is being done in increasing frequency worldwide where formation of epidural scar formation has been known as a common cause of its failure. Application of a free fat graft despite controversies has been widely used to prevent further adhesion and post-laminectomy scarring. Single nerve root compression and cauda equina syndrome due to compressive effect of free fat graft with a few days to weeks after laminectomy is well known early complication of lumbar discectomy. However, late neurological deficit as the result of significant increase of fat graft volume has been not addressed previously in the literature. Herein, the authors present a middle-age man who was admitted with cauda equina syndrome for one day duration developing 11 years after a redo laminectomy for recurrent disc herniation and local stenosis. The MRI obtained urgently revealed significant overgrowth of the free fat graft that had been already used for prevention of scar formation. Piecemeal surgical removal of fat with clearance of the theca and the corresponding nerve roots result in steady but good recovery within a few weeks. To our knowledge, although overgrowth of fat has been reported in other locations, but this is the first example occurring after its application at the site of laminectomy. Therefore, overgrowth of free fat graft should be added to all previously describe unusual complication of lumbar discectomy.
全世界进行腰椎间盘切除术的频率越来越高,硬膜外瘢痕的形成已被认为是其失败的常见原因。尽管存在争议,但游离脂肪移植物的应用已被广泛用于防止进一步粘连和椎板切除术后瘢痕形成。椎板切除术后几天至几周游离脂肪移植物的压迫作用导致的单神经根压迫和马尾综合征是众所周知的腰椎间盘切除术的早期并发症。然而,由于脂肪移植物体积显著增加而导致的晚期神经系统缺陷在以前的文献中没有得到解决。在此,作者介绍了一名中年男子,他因马尾综合征入院一天,在因复发性椎间盘突出和局部狭窄进行椎板切除术后发展为11年。紧急获得的MRI显示,已经用于预防瘢痕形成的游离脂肪移植物明显过度生长。在清除鞘和相应神经根的情况下,通过局部手术去除脂肪,可以在几周内稳定但良好地恢复。据我们所知,尽管在其他地方也有脂肪过度生长的报道,但这是在椎板切除术后出现的第一个例子。因此,游离脂肪移植物的过度生长应添加到所有先前描述的腰椎间盘切除术的异常并发症中。
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引用次数: 1
Early Decompressive Craniectomy in Conjunction with Medical Management in the Treatment of Severe Traumatic Brain Injury: A Case Report 早期开颅减压联合医疗管理治疗重型颅脑损伤1例报告
Pub Date : 2017-11-06 DOI: 10.4172/2325-9701.1000277
Michael J DeRogatis, M. Shenouda, G. Hinika, P. Issack, A. Loo, A. Salem
We present the case of a 20-year-old man with an initial Glasgow Coma Scale (GCS) of 4 secondary to traumatic brain injury. Computed tomography of the head demonstrated diffuse cerebral edema, an acute right frontal subdural hematoma with a right-toleft midline shift, and subarachnoid hemorrhage. Surgical treatment with early decompressive craniectomy (DC) and duraplasty improved the patient’s GCS score to 15 by postoperative day 3. While there are several reports on early DC for traumatic brain injury, there has been as to date no level 1 evidence proving it to be superior to medical management alone or other neurosurgical techniques including routine temporparietal craniectomy.
我们报告了一例20岁男性,其格拉斯哥昏迷评分(GCS)为4,继发于创伤性脑损伤。头部计算机断层扫描显示弥漫性脑水肿、急性右额硬膜下血肿伴右左中线移位和蛛网膜下腔出血。早期减压颅骨切除术(DC)和硬脑膜成形术的手术治疗在术后第3天将患者的GCS评分提高到15分。虽然有几篇关于创伤性脑损伤早期DC的报道,但到目前为止,还没有一级证据证明它优于单独的医疗管理或其他神经外科技术,包括常规的临时颅骨切除术。
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引用次数: 0
The Effect of Core Muscle Training on Cardiopulmonary Function in Parkinson disease 核心肌群训练对帕金森病患者心肺功能的影响
Pub Date : 2017-11-06 DOI: 10.4172/2325-9701.1000276
Yanqun Huang, Yangyang Zhao, Caiyou Hu, Zhixin Wu, Li Lian, Heinz Lowis, Mingsheng Zhang, Y. Jianrong, Mingming Zhao
Core Muscle mainly including the rectus abdominis, the oblique muscle, the lower back muscle and shaft sma, which located around the abdomen. It is an important muscle group responsible for protecting the stability of the spine. At present, core muscle group training is mainly aimed at Athletes, Stroke, Lumbar disc herniation and Parkinson’s Disease. However, quite few people did the research about the effects of exercise training on cardiopulmonary function in Parkinson’s patients. Therefore, this review summarized the effects of Core Muscle Training on cardiopulmonary function from its evaluating the parameters.
核心肌主要包括腹直肌、斜肌、下背部肌肉和位于腹部周围的股骨干肌。它是一个重要的肌肉群,负责保护脊椎的稳定性。目前,核心肌群训练主要针对运动员、脑卒中、腰椎间盘突出症和帕金森病。然而,很少有人研究运动训练对帕金森病患者心肺功能的影响。因此,本文从评价核心肌训练参数的角度综述了核心肌训练对心肺功能的影响。
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引用次数: 0
Innovative Treatment for Pre- Operative Occipital Nerve Pain Associated with Chiari 0 Malformation 手术前枕神经疼痛伴Chiari畸形的创新治疗方法
Pub Date : 2017-11-06 DOI: 10.4172/2325-9701.1000281
M. Stephens, E. King, Tuong Vy Dang, L. Nagy, G. Racz
Chiari 0 malformation is a disorder within the spectrum of Arnold- Chiari malformations characterized by cerebellar changes present during fetal development and early childhood. Specifically, Chiari 0 is classified by characteristics that include either lack of protrusion of the cerebellar tonsils into the foramen magnum or protrusion less than 5 millimeters, which is the current minimum cutoff for Chiari I classification. Due to the subtle changes in the cerebellar region regarding Chiari 0, patients with this malformation often present with neck and occipital pain along with occipital headaches. It is suggested that this may be due to abnormal blockage of cerebrospinal fluid (CSF) that causes entrapment and impingement of the occipital nerve. In the cases of two teenage patients, both were referred to Pediatric Neurosurgery in Lubbock, Texas for complaints of chronic headaches and neck pain. After previous pain remedies proved to be unsuccessful in providing lasting relief, the patients were deemed candidates to receive an innovative treatment option to manage their chronic headaches and neck pain. The patients were referred to receive epidural lysis of adhesions (LOA) which would provide the lasting relief that the patients were seeking. LOA is a procedure that includes using a needle, Racz catheter, and injectable contrast guided with fluoroscopy to locate the entrapment of the occipital nerve. LOA utilizes the injection of hyaluronidase dissolved in normal saline to free the entrapped nerve so that a local anesthetic/steroid solution can be injected to provide pain relief. Lysis of adhesions should be considered as a minimally invasive treatment for Chiari 0 malformations, whose primary symptoms are intractable occipital headaches.
Chiari 0畸形是Arnold-Chiari畸形的一种疾病,其特征是胎儿发育和儿童早期出现的小脑变化。具体来说,Chiari 0是根据小脑扁桃体没有突出到大孔或突出小于5毫米的特征进行分类的,这是目前Chiari I分类的最小截止值。由于Chiari 0小脑区的细微变化,该畸形患者通常表现为颈部和枕部疼痛以及枕部头痛。有人认为,这可能是由于脑脊液(CSF)异常堵塞,导致枕神经卡压和撞击。在两名青少年患者的案例中,两人都因抱怨慢性头痛和颈部疼痛而被转诊到德克萨斯州拉伯克的儿科神经外科。在之前的疼痛疗法被证明无法提供持久的缓解后,这些患者被认为是接受创新治疗选择的候选人,以控制他们的慢性头痛和颈部疼痛。患者被转诊接受硬膜外粘连松解术(LOA),这将提供患者所寻求的持久缓解。LOA是一种程序,包括使用针头、Racz导管和荧光镜引导下的可注射造影剂来定位枕神经的卡夹。LOA利用注射溶解在生理盐水中的透明质酸酶来释放被包裹的神经,从而可以注射局部麻醉剂/类固醇溶液来提供疼痛缓解。对于Chiari 0畸形,其主要症状是顽固性枕叶头痛,应将粘连溶解视为一种微创治疗方法。
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引用次数: 0
Clinical Analysis of Thoracic Pathologies Accompanying Thoracic Spine Fractures Occurring after Spinal Cord Injury 脊髓损伤后并发胸椎骨折的临床病理分析
Pub Date : 2017-11-06 DOI: 10.4172/2325-9701.1000280
N. Aydın
Spinal cord injuries continue to be a significant problem due to its high prevalence in young and productive people, the magnitude of the impact on physical, psychosocial and economic aspects, and lack of a treatment protocol widely accepted in the literature. Spinal cord injury (SCI) is an important cause of mortality and morbidity that has been the focus of research for many years.
脊髓损伤仍然是一个重大问题,因为它在年轻人和有生产力的人中很普遍,对身体、心理社会和经济方面的影响很大,并且缺乏文献中广泛接受的治疗方案。脊髓损伤(SCI)是导致死亡和发病的重要原因,多年来一直是研究的焦点。
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引用次数: 0
Relationship between Cutaneous Silent Period Characteristics and Lesion Site in the Cervical Spinal Cord 颈脊髓皮肤静默期特征与病变部位的关系
Pub Date : 2017-07-11 DOI: 10.4172/2325-9701.1000275
N. Tadokoro
Objective: The transient suppression of voluntary muscle contraction after nociceptive stimulation is termed the cutaneous silent period (CSP), and is thought to be a spinal inhibitory reflex mediated by A-delta fibers. In CSP testing using the abductor pollicis brevis (APB) muscle (C8-T1 myotome) and the index finger (C6-C7 dermatome), the intramedullary CSP circuit is thought to be localized to the C6-T1 spinal segments. Notably, CSPs are altered or abolished in cervical cord disorders. However, the association between the site of cord lesion and CSP changes is not clearly defined. Methods: We prospectively reviewed the onset latency and duration of preoperative CSPs in 40 hands from 22 patients with cervical compression myelopathy (CCM) and single-level cord compression. CCM patients were divided into 2 groups: those with compression involving the C6-T1 spinal segments (CCM at the middle and lower cervical spine, the ML group; 10 hands) or other segments (CCM at the upper cervical spine; the U group, 30 hands). Results: Onset latency was significantly delayed in the ML group compared to the U group (P = 0.0001), whereas duration was not significantly different between groups (P = 0.9). Conclusion: Changes in the CSP onset latency were influenced by the CCM lesion site. The results of this study inform the evaluation of patients with cervical cord disorders when using CSP testing.
目的:痛觉刺激后随意肌收缩的短暂抑制被称为皮肤沉默期(CSP),被认为是由a -delta纤维介导的脊髓抑制性反射。在使用外展拇短肌(APB) (C8-T1肌组)和食指(C6-C7皮组)进行CSP测试时,髓内CSP回路被认为定位于C6-T1脊柱节段。值得注意的是,csp在颈髓疾病中被改变或废除。然而,脊髓病变部位与CSP变化之间的关系尚不明确。方法:我们前瞻性地回顾了22例颈压迫性脊髓病(CCM)和单节段脊髓压迫患者的40手CSPs的发病潜伏期和术前持续时间。CCM患者分为2组:累及C6-T1脊柱节段的CCM组(中下颈椎CCM组,ML组;(10只手)或其他节段(上颈椎的CCM;U组,30只手)。结果:与U组相比,ML组的发病潜伏期明显延迟(P = 0.0001),而组间持续时间无显著差异(P = 0.9)。结论:CSP发病潜伏期的变化受CCM病变部位的影响。本研究的结果为使用CSP检测评估颈髓疾病患者提供了依据。
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引用次数: 1
Intradiscal Retained Broken Blade Of A Disc Rongeur 椎间盘内保留的折断的刀片
Pub Date : 2017-07-06 DOI: 10.4172/2325-9701.1000273
A. Rahimizadeh
Lumbar discectomy is done in increasing frequency worldwide. A rare event associated with this procedure is breaking of the disc forceps blade during discectomy. In majority the broken part of the disc forceps can be removed during the initial surgery. But, rarely, the surgeon’s attempts might be unsuccessful, resulting in intradiscal retained foreign body. Literature regarding this issueis scarce, although there might be cases that have been never reported because of the medico legal consequences. Furthermore, until recently, there have been no guidelines to address this complication. Herein, a middle age woman in whom the blade of disc forceps was broken during L5-S1 discectomy is presented. Her surgeon could not remove the broken blade, so it was retained. .Once the patient and her family became aware about this event, began to seek medical advice .In our institute, retrieval of the broken blade of the disc forceps became possible via transforaminal corridor. Thereafter, posterior screw rod fixation and L5-S1 interbody fusion was done. To our knowledge, the reports about the broken surgical instruments being retained in the disc space are extremely rare complication of lumbar discectomy. Moreover, xtraforaminal or transforaminal corridor might an appropriate alternative option instead of anterior or anterolateral approaches.
腰椎间盘切除术在世界范围内的频率越来越高。与此手术相关的一个罕见事件是椎间盘切除术中椎间盘钳刀片断裂。大多数情况下,椎间盘钳的断裂部分可以在初次手术中取出。但是,很少有外科医生的尝试会失败,导致椎间盘内残留异物。关于这个问题的文献很少,尽管可能有一些病例由于医疗法律后果而从未报告过。此外,直到最近,还没有解决这一复杂问题的指导方针。本文报告一位中年妇女在L5-S1椎间盘切除术中椎间盘钳刀片断裂。她的外科医生无法取出断了的刀片,所以它被保留了下来。一旦患者和她的家人意识到这一事件,就开始寻求医疗建议。在我们的研究所,可以通过椎间孔通道取出椎间盘钳的断刃。之后,进行后路螺钉固定和L5-S1椎间融合术。据我们所知,关于手术器械破损保留在椎间盘间隙的报道是腰椎间盘切除术中极为罕见的并发症。此外,椎间孔外或经椎间孔通道可能是替代前路或前外侧入路的合适选择。
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引用次数: 2
Primary Extradural Peripheral Primitive Neuroectodermal Tumor (Extraskeltal Ewing’s Sarcoma) Arising from the Sacral Spinal Nerve Root: A Case Report and Review of the Literature 源于骶脊神经根的原发性硬膜外周围原始神经外胚层肿瘤(骨外尤因肉瘤)1例报告及文献复习
Pub Date : 2017-05-11 DOI: 10.4172/2325-9701.1000265
T. Funayama, T. Tsukanishi
Primitive neuroectodermal tumors (PNET) are rare, and are even rarer when they arise from the spinal cord tissue. Therefore, we report a case of peripheral PNET that arose from the sacral spinal nerve root. The patient was a 30-year-old woman who presented with left lower extremity pain, and MRI revealed a neoplastic lesion in the left S1 nerve root canal of the sacral region. Subsequent imaging and testing were not able to confirm a diagnosis, although we suspected a benign tumor as a candidate for the differential diagnosis. We performed surgery to remove the tumor, and confirmed total resection. Our subsequent pathological testing confirmed a diagnosis of peripheral PNET, and we elected to treat the patient using concurrent radiotherapy and the standard chemotherapy for Ewing’s sarcoma. The treatment was successful, and the patient was free from recurrence at the 27-month follow-up. Although it may be impossible to achieve a preoperative imaging diagnosis in similar cases, we believe that imaging remains an important part of the differential diagnosis to facilitate successful treatment.
原发性神经外胚层肿瘤(PNET)是罕见的,当它们起源于脊髓组织时更为罕见。因此,我们报告了一例由骶脊神经根引起的外周PNET。患者是一名30岁的女性,表现为左下肢疼痛,MRI显示左侧骶部S1神经根管有肿瘤性病变。尽管我们怀疑良性肿瘤是鉴别诊断的候选者,但随后的成像和测试无法确认诊断。我们进行了切除肿瘤的手术,并确认全切除。我们随后的病理检查证实了外周PNET的诊断,我们选择同时使用放疗和标准化疗治疗尤因肉瘤。治疗是成功的,患者在27个月的随访中没有复发。尽管在类似病例中可能不可能实现术前影像学诊断,但我们相信,影像学仍然是鉴别诊断的重要组成部分,有助于成功治疗。
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引用次数: 0
期刊
Journal of spine & neurosurgery
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