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Myelopathy’s Worsening Due to Adjacent Peroperative Discal Herniatio: Case Report. 术中相邻椎间盘突出导致脊髓病恶化1例。
Pub Date : 2020-08-31 DOI: 10.4172/2325-9701.1000342
P. Roblot, C. Roscop, J. Vital, O. Gille, K. Fara
We report the case of a 62-old patient who suffered from immediate post-operative cervical spondylotic myelopathy’s worsening. This is a rare complication due to patient positioning the most often. This case seems to be the first case due to a disk herniation described to the best of our knowledge. This patient was operated by C4 and C5 corpectomy because of a spinal cord compression associated with intra-medullary T2-weighted hyper signal. Neurological worsening with immediate motor deficit was noted in postoperative care unit. An immediate cervical spine MRI scan was done showing a discal fragment at C6-C7 level. Emergency surgery was so performed with a C6-C7 transdiscal way for resection of a compressive cervical herniation. During the immediate postoperative outcome, the neurological enhancing was subtotal. We think that emergency MRI scan is mandatory for immediate postoperative neuroworsening after anterior cervical spine surgery instead of emergency surgery if neuroworsening is not tetraplegia in order to avoid a diagnosis misunderstanding.
我们报告了一例62岁的脊髓型颈椎病术后立即恶化的患者。这是一种罕见的并发症,因为患者最常定位。据我们所知,这个病例似乎是第一个因椎间盘突出引起的病例。该患者接受了C4和C5椎体切除术,因为脊髓压迫伴有髓内T2加权超信号。术后监护室发现神经系统恶化并伴有即时运动功能障碍。立即进行颈椎MRI扫描,显示C6-C7水平的椎间盘碎片。紧急手术是用C6-C7跨椎间盘切除压迫性颈椎突出症。在术后即刻的结果中,神经功能增强是次全。我们认为,如果神经恶化不是四肢瘫痪,那么在颈椎前路手术后立即进行术后神经恶化的情况下,必须进行紧急MRI扫描,而不是紧急手术,以避免诊断误解。
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引用次数: 1
One-Year NDI and VAS Outcomes from the Single-Level PEEK-on-Ceramic SimplifyTM Disc FDA IDE Trial 单级PEEK在陶瓷SimplifyTM椎间盘FDA IDE试验中的一年NDI和VAS结果
Pub Date : 2019-03-28 DOI: 10.4172/2325-9701.1000320
F. Geisler, D. Maislin, B. Keenan, G. Maislin
This study was performed to evaluate the early clinical results at one year for the Simplify™ Cervical Artificial Disc. We compared outcomes for 150 Simplify Disc subjects at one-year followup in a prospective, multicenter, FDA IDE clinical trial with 119 propensity score matched historical control subjects who received conventional anterior cervical discectomy and fusion (ACDF) for single-level cervical degenerative disc disease. The outcome measures included the change from preoperative baseline to one-year in Neck Disability Index (NDI) and visual analog scales (VAS) for neck and arm pain, with scores for the few missing oneyear follow-up implicitly imputed using mixed models for repeated measures (MMRM). The MMRM was used to estimate within group and between group differences controlling for propensity score subclass and the relevant baseline value. The adjusted mean changes (and standard errors) in NDI from baseline to one year were -46.7 (SE=1.7, p<0.001) and -38.1 (SE=1.9, p<0.001) for Simplify Disc subjects and ACDF control subjects, respectively. The adjusted Simplify Disc vs. control difference in mean NDI change at one year was -8.7 (SE=2.7) with p=0.002; the 95% confidence interval for the mean difference was -14.0 to -3.3. The adjusted mean changes in VAS neck and arm pain from baseline to one year were -62.4 (SE=2.0, p<0.001) and -55.2 (SE=2.3, p<0.001) for Simplify Disc and ACDF controls, respectively. The adjusted Simplify Disc vs. control difference in mean VAS neck and arm pain change at one year was -7.3 (SE=3.3) with p=0.029 (95% CI -13.8 to 0.8). Therefore, it can be concluded that the one-year clinical results of the Simplify Disc are superior to ACDF for both 1) improvement of NDI and 2) improvement in VAS neck and arm pain. Inspection of all eight prior FDA cervical total disc replacement studies indicates that these good results for the Simplify Disc can be expected to continue for five years and beyond, but longer term follow-up is necessary for verification.
本研究旨在评估Simplify在一年内的早期临床结果™ 颈椎人工椎间盘。在一项前瞻性、多中心、美国食品药品监督管理局IDE临床试验中,我们比较了150名Simplify Disc受试者在一年随访中的结果,其中119名倾向评分匹配的历史对照受试者接受了常规颈前路椎间盘切除融合术(ACDF)治疗单级颈椎退行性椎间盘疾病。结果测量包括从术前基线到一年颈部残疾指数(NDI)和颈部和手臂疼痛视觉模拟量表(VAS)的变化,少数缺失的一年随访的分数使用重复测量混合模型(MMRM)隐式估算。MMRM用于估计组内和组间的差异,控制倾向评分亚类和相关基线值。简化椎间盘受试者和ACDF对照受试者从基线到一年的NDI调整平均变化(和标准误差)分别为-46.7(SE=1.7,p<0.001)和-38.1(SE=1.9,p<0.001)。一年时,经调整的Simplify椎间盘与对照组的平均NDI变化差异为-8.7(SE=2.7),p=0.002;平均差异的95%置信区间为-14.0至-3.3。Simplify Disc和ACDF对照组的颈部和手臂疼痛VAS从基线到一年的调整平均变化分别为-62.4(SE=2.0,p<0.001)和-55.2(SE=2.3,p<0.001)。一年平均VAS颈部和手臂疼痛变化的Simplify Disc与对照组的调整差异为-7.3(SE=3.3),p=0.029(95%CI-13.8-0.8)。因此,可以得出结论,Simplify Disc一年的临床结果在1)改善NDI和2)改善VAS颈部和臂部疼痛方面均优于ACDF。对美国食品药品监督管理局先前所有八项宫颈全椎间盘置换研究的检查表明,Simplify椎间盘的这些良好结果预计将持续五年及更长时间,但需要进行长期随访以进行验证。
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引用次数: 3
Spinal Epidermoid Tumor – A Rare and Silent Occurrence 脊柱表皮样肿瘤——一种罕见且无症状的发生
Pub Date : 2019-03-25 DOI: 10.4172/2325-9701.1000319
L. Cardoso, R. Nogueira, Lino Fonseca, A. Nabais
Objective: Epidermoid tumors are slow-growing benign lesions lined by squamous epithelium. Are rare, commonly intracranial and spinal intradural epidermoid tumors are extremely rare. The authors propose to describe a clinical case of a patient operated. Methods: We report a 75-year-old male referred to neurosurgical consultation by spondylolisthesis at L4-L5 with stenotic spinal canal and a left L4-L5 foraminal stenosis, revealed by lumbosacral CT scan. Neurologic exam revealed a claudicant gait, spastic paraparesis with muscular strenght of 3-/5 at left and 4+/5 at right. Deep tendon reflexes were increased at left with presence of patelar and ankle clonus, but normally at right. Below left D5 dermatome, he had sensory parestesia. MRI showed an intradural lesion, apparently exclusively extra-medullary at D6 level. This lesion determines a significant spinal cord compression and had identical signal to the CSF in all MRI ponderations. It was performed a D5 laminectomy and median linear durotomy with identification of an intradural tumor (pearl-white color), adjacent to the arachnoid, dissectable from spine cord. Gross total resection was achieved. Results: Postoperatively the patient remained clinically stable and without new deficits. At the 4th month of follow-up the patient progressively recovered and was presenting with muscle strength grade 4/5. Histopathology showed a sample of keratin lamellae, foci of gross calcification, compatible with diagnosis of epidermoid tumor. Conclusion: This case demonstrates that even being a rare pathology we must have it present in our clinical reasoning so we can diagnose it properly. It also reveals a case of associated pathology of the spine, which could delay the diagnosis, increasing the risk of worsening of permanent neurological deficit. The goal is always the complete surgical resection and so, because of is benign nature and low rate of recurrence the patients may improve clinically and can be considered cured.
目的:表皮样肿瘤是一种生长缓慢的、以鳞状上皮为衬里的良性病变。是罕见的,常见于颅内和脊髓硬膜内的表皮样瘤极为罕见。作者建议描述一个手术患者的临床病例。方法:我们报告一名75岁男性,腰骶部CT扫描显示腰4- l5椎管狭窄伴左L4-L5椎间孔狭窄,因腰椎滑脱而就诊神经外科。神经学检查显示步态跛行,痉挛性截瘫,左侧肌肉力量3-/5,右侧肌肉力量4+/5。左侧深腱反射增加,伴有髌骨和踝关节阵挛,但右侧正常。左下D5皮区,感觉失敏。MRI显示硬膜内病变,D6水平明显为髓外病变。该病变确定了明显的脊髓压迫,在所有MRI检查中与脑脊液有相同的信号。患者行D5椎板切除术和正中线状硬膜切开术,发现硬膜内肿瘤(珍珠白色),靠近蛛网膜,可从脊髓中剥离。全部切除。结果:术后患者临床稳定,无新发缺损。随访第4个月,患者逐渐恢复,肌肉力量等级为4/5。组织病理学显示角蛋白片样,大体钙化灶,符合表皮样瘤的诊断。结论:这个病例表明,即使是一种罕见的病理,我们也必须在我们的临床推理中发现它,这样我们才能正确诊断它。它也揭示了一个病例的相关病理的脊柱,这可能延误诊断,增加了永久性神经功能障碍恶化的风险。手术的目的始终是完全切除,因此,由于其良性,复发率低,患者在临床上可能会好转,可以认为治愈。
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引用次数: 0
Spontaneous C1 Anterior Arch Fracture Following C1 Laminectomy for Cervical Meningioma: A Case Report and Review of Literature 颈椎脑膜瘤C1椎板切除术后自发性C1前弓骨折1例报告及文献复习
Pub Date : 2019-03-01 DOI: 10.4172/2325-9701.1000317
S. Bejell, Sviridova Ge
Trigeminal Neuralgia is a common condition affecting the quality of life of millions across the world. The introduction of Microvascular decompression has significantly added to the armamentarium of the neurosurgeon in tackling this dreaded disease. Some anatomical variants where large ectatic basilar and vertebral arteries compressing on the Vth nerve are challenging to tackle. Many suggestions such as fascia vasculopexy, Teflon vasculopexy and sub temporal realignment of the basilar have been proposed to address the situation. We propose a simple technique where Teflon rings taken from a vascular graft are used to shield the nerve from the arteries in question, thereby liberating it from the pulsatile pressure of the vessels. We present our experiences regarding this novel technique here.
三叉神经痛是影响全世界数百万人生活质量的常见疾病。微血管减压的引入大大增加了神经外科医生应对这种可怕疾病的装备。一些解剖学变异,其中巨大的扩张性基底动脉和椎动脉压迫Vth神经是很难解决的。已经提出了许多建议,如筋膜血管固定术、特氟隆血管固定术和基底颞下重新排列来解决这种情况。我们提出了一种简单的技术,用从血管移植物上取下的聚四氟乙烯环来保护神经免受动脉的影响,从而将其从血管的脉动压力中解放出来。我们在这里介绍我们对这种新颖技术的经验。
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引用次数: 0
Early Clinical Outcomes Comparing Porous PEEK, Smooth PEEK, and Structural Allograft Interbody Devices for Anterior Cervical Discectomy and Fusion 多孔PEEK、光滑PEEK和结构型同种异体移植物椎间盘融合术的早期临床疗效比较
Pub Date : 2019-03-01 DOI: 10.4172/2325-9701.1000318
Clint P. Hill, K. Br, on Strenge
Background: Recently, material surface advancements have been promoted to improve spinal implant osseointegration. While rough and porous titanium implants have gained traction due to their osteoconductive properties, polyetheretherketone (PEEK) devices have remained popular due to their radiographic properties and similar modulus of elasticity to bone. However, traditional smooth PEEK devices elicit fibrous tissue responses leading to poor implant osseointegration. Recently, PEEK implants have been developed with surface porosity allowing for direct bone in-growth. Despite preclinical data suggesting implant osseointegration with porous PEEK implants, comparative clinical results between implants with and without porous surface architecture are heretofore reported. The objective of this single-site retrospective study was to comparatively evaluate early clinical efficacy in patients undergoing ACDF treated with porous PEEK interbody implants to patients treated with structural allograft or traditional smooth PEEK implants. Methods: 167 consecutive patients presenting with cervical degenerative disc disease and radiculopathy underwent ACDF using one of three implants (porous PEEK (Cohere®, NuVasive Inc., San Diego, CA), structural allograft, or smooth PEEK). After preop evaluation and surgery, patients were followed per standard of care 0.5, 1.5, 3, 6, and 12 months post-op. At each time, patient outcomes were measured by disability (Neck Disability Index) and pain (visual analogue score (VAS) neck/arm pain). Results: Patients treated with porous PEEK implants achieved significantly greater NDI and neck pain improvement by 6 weeks post-op when compared to patients receiving structural allograft or smooth PEEK devices. These significantly greater NDI and neck pain improvements for patients treated with porous PEEK devices compared to structural allograft and smooth PEEK were sustained through 12 months post-op. Conclusion: 12 month follow-up data in patients with degenerative disc disease and radiculopathy demonstrates a clear benefit of porous PEEK in promoting improved early outcomes over structural allograft and smooth PEEK in ACDF procedures.
背景:近年来,材料表面的进步已被促进,以改善脊柱植入物的骨整合。虽然粗糙和多孔的钛植入物由于其骨传导特性而获得了牵引力,但聚醚醚酮(PEEK)装置由于其射线照相特性和与骨骼相似的弹性模量而仍然很受欢迎。然而,传统的光滑PEEK装置会引起纤维组织反应,导致种植体骨整合不良。最近,PEEK植入物已经被开发出具有表面孔隙率,允许直接骨生长。尽管临床前数据表明植入物与多孔PEEK植入物骨结合,但迄今为止,有报道称具有和不具有多孔表面结构的植入物之间的比较临床结果。这项单点回顾性研究的目的是比较评估接受多孔PEEK椎体间植入物治疗的ACDF患者与接受结构同种异体移植物或传统光滑PEEK植入物治疗患者的早期临床疗效。方法:167例连续出现颈椎退行性椎间盘疾病和神经根病的患者使用三种植入物之一(多孔PEEK(Cohere®,NuVasive股份有限公司,加利福尼亚州圣地亚哥)、结构同种异体移植物或光滑PEEK)进行ACDF。术前评估和手术后,患者在术后0.5、1.5、3、6和12个月按照标准护理进行随访。每次,通过残疾(颈部残疾指数)和疼痛(视觉模拟评分(VAS)颈部/手臂疼痛)来衡量患者的结果。结果:与接受结构同种异体移植物或光滑PEEK装置的患者相比,接受多孔PEEK植入物治疗的患者在术后6周时获得了显著更大的NDI和颈部疼痛改善。与结构同种异体移植物和光滑PEEK相比,使用多孔PEEK装置治疗的患者的NDI和颈部疼痛改善显著更大,手术后12个月持续。结论:退行性椎间盘疾病和神经根病患者12个月的随访数据表明,在ACDF手术中,多孔PEEK在促进早期结果改善方面明显优于结构同种异体移植物和光滑PEEK。
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引用次数: 7
Luxation of the First Costovertebral Joint after Trauma of the Thorax 胸部创伤后第一肋椎关节脱位
Pub Date : 2019-02-22 DOI: 10.4172/2325-9701.1000309
Van Groningen Nj, Wijffels Mme
Thoracic trauma is common and may vary from simple contusions to lethal injuries. Uncommon thoracic injury is a costovertebral luxation of the first rib. Up till now only one other case report has been written in 1980. Therefore a case with this injury is presented.
胸部创伤是常见的,可能从简单的挫伤到致命的损伤。罕见的胸部损伤是第一根肋骨的肋椎骨脱位。到目前为止,只有一份1980年的病例报告。因此,提出了一个这种损伤的案例。
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引用次数: 2
Spinal Ischemia Secondary to Central Spine Thoracic Hernia 中枢性胸脊疝继发性脊髓缺血
Pub Date : 2019-02-22 DOI: 10.4172/2325-9701.1000315
Caroline Figueiredo da Silva, C. Machado, Heloisa da Silva Schafaschek, Andre Possamai, M. R. Lang, Julio Aguiar Junior, M. Gonçalves
The thoracic spinal cord is most vulnerable to compression due to the space restriction between the spine and the thoracic spinal canal, and progressive neurological deficit is common. Magnetic resonance imaging (MRI) allows for the diagnosis of vascular diseases, given that the presence of neurological deficit involves other differential diagnoses. This case study’s main goal is to report a case about spinal infarct with surgical procedure of spinal decompression and bring a brief overview of current literature.
由于脊柱和胸椎管之间的空间限制,胸椎最容易受到压迫,进行性神经功能缺损很常见。磁共振成像(MRI)可以诊断血管疾病,因为神经系统缺陷的存在涉及其他鉴别诊断。本病例研究的主要目的是报告一例采用脊柱减压手术治疗的脊髓梗死病例,并对现有文献进行简要综述。
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引用次数: 0
Surgical Management of an Elderly Patient with Free Floating Os Odontoideum 老年游离游离齿状突骨的手术治疗
Pub Date : 2019-02-21 DOI: 10.4172/2325-9701.1000312
A. Rahimizadeh, W. Williamson, Shaghayegh Rahimizadeh, Mahan Amirzadeh
Os odontoideum (OO) is defined as an ossicle with smooth circumferential cortical margins representing the odontoid process that has no osseous continuity with the body of the C2 vertebrae. This pathology usually becomes symptomatic in the second or third decade of life. Middle-age individuals display the second highest incidence. However, the discovery of an OO in elderly individuals over the age of 67 years is rather scarce and has been confined to only 11 recorded cases. Here in the authors present a new symptomatic patient possessing an OO who is elderly.
ododontoideum (OO)被定义为具有光滑的周向皮质边缘的小骨,代表与C2椎体无骨连续性的齿状突。这种病理通常在生命的第二或第三个十年出现症状。中年人的发病率第二高。然而,在67岁以上的老年人中发现OO相当罕见,仅记录了11例病例。在这里,作者提出了一个新的症状患者拥有一个OO谁是老年人。
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引用次数: 1
Spontaneous Spinal Epidural Haematomas in Adults: A Systematic Review 成人自发性脊膜外血肿的系统评价
Pub Date : 2019-02-21 DOI: 10.4172/2325-9701.1000313
Soltani S, Nogaro Mc, Haleem S, Rupani N, Pyrovolou N, Kieser Dc
Study design: Systematic review Objectives: Understand the typical presentation, risk factors, location, size, treatment and outcome of spontaneous spinal epidural haematomas (SSEH). Methods: Systematic review of the English literature from 1 January 1960 to 1 March 2018. Individual patient data was extracted and collated. Outcome measures were mode of presentation, risk factors, initial neurological findings, presumed diagnosis, diagnostic investigations, site and size of the SSEH, treatment, neurological recovery and survival. Results: 160 publications (254 patients) were reviewed. Most patients (98%) presented with back pain and radicular pain. Pregnancy was common in those aged under 40years (24%), whereas anticoagulation therapy (30%) and hypertension (30%) was common in those aged 50-80years. Most patients present with neurological dysfunction. 15% were initially suspected of having an alternative diagnosis, including 7.5% who were suspected of ischaemia for which anti-coagulation therapy was either planned or given. MRI and/or CT myelogram was performed in 98% of cases. The mid-cervical spine and cervico-thoracic junction were most commonly affected and the average haematoma size extended across 5.4 vertebral levels. Most patients underwent surgical decompression (76%) and most improved their neurological function (85%). Conclusions: SSEH affects all age groups and presents with variable neurological signs sometimes mimicking cerebral or cardiac ischaemia. Cross-sectional spinal imaging with MRI or CT is diagnostic and avoids inappropriate anticoagulation therapy. Most SSEHs are located in the mid-cervical spine and cervico-thoracic junction and affect multiple spinal levels. Surgical intervention is not always indicated, but with appropriate management most patients will improve or resolve their neurological deficit.
研究设计:系统综述目的:了解自发性脊髓硬膜外血肿(SSEH)的典型表现、危险因素、位置、大小、治疗和结果。方法:系统回顾1960年1月1日至2018年3月1日的英国文献。提取并整理了个别患者的数据。结果指标包括表现模式、风险因素、初步神经系统发现、推测诊断、诊断调查、SSEH的部位和大小、治疗、神经系统恢复和生存率。结果:对160篇文献(254例患者)进行了回顾性分析。大多数患者(98%)表现为背痛和神经根疼痛。妊娠在40岁以下的人群中很常见(24%),而抗凝治疗(30%)和高血压(30%)在50-80岁的人群中也很常见。大多数患者表现为神经功能障碍。15%的患者最初被怀疑有替代诊断,其中7.5%的患者被怀疑患有计划或给予抗凝治疗的缺血。98%的病例进行了MRI和/或CT骨髓图检查。颈椎中段和颈胸交界处最常受到影响,平均血肿大小延伸至5.4个椎骨水平。大多数患者接受了手术减压(76%),大多数患者的神经功能得到改善(85%)。结论:SSEH影响所有年龄组,并表现出不同的神经系统体征,有时类似于脑缺血或心脏缺血。MRI或CT的脊柱横断面成像是诊断性的,可以避免不适当的抗凝治疗。大多数SSEH位于颈椎中段和颈胸交界处,影响多个脊柱水平。手术干预并不总是指代性的,但通过适当的管理,大多数患者将改善或解决他们的神经系统缺陷。
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引用次数: 3
C1 Arch Reconstruction: A Novel Alternative to Fusion in Maintaining Mobility of the Atlanto-Axial Joint C1弓重建:维持寰枢关节活动的新选择
Pub Date : 2019-02-21 DOI: 10.4172/2325-9701.1000310
S. Ganapathy, T. Ramakrishna, S. Gopal
First decribed by Sir Goeffrey Jefferson in London in 1924, the term Jefferson’s fracture has become an eponym for all fractures of the Atlas. Complex Jefferson fractures and unstable Jefferson fractures require surgical fusion to maintain stability of the spinal axis. This however results in debilitating loss of movement at the crucial C1C2 joint, the most versatile of spinal joints where stability and mobility are intricately balanced into a complex yet supremely agile structure. The desire to attempt in some way to preserve a degree of movement and to spare the patient the crippling loss of movement at this joint has led to many attempts at innovation, both surgical and technological. This has led to the discovery of C1 osteosynthesis. This revolutionary technique enables the anatomical fixation of the defect thus allowing motion preservation without compromising on stability, which is a major advantage given the extreme importance of both to the proper functioning of the C1C2 and C1C0 joints. We present a case report of a 54 year old man with an isolated Jefferson’s fracture which was treated successfully by this technique. We also present an overview of the biomechanics of C1 injury and the relevant review of literature regarding options for management of complex C1C2 injuries.
1924年,杰弗里·杰斐逊爵士在伦敦首次描述了这种骨折,“杰斐逊骨折”一词已成为阿特拉斯山脉所有骨折的代名词。复杂杰弗逊骨折和不稳定杰弗逊骨折需要手术融合术来维持脊柱轴的稳定。然而,这会导致至关重要的C1C2关节运动能力丧失,这是最通用的脊柱关节,其稳定性和机动性被复杂地平衡成一个复杂但极其敏捷的结构。试图以某种方式保持一定程度的活动,避免患者在关节处失去活动能力的愿望导致了许多创新的尝试,包括手术和技术。这导致了C1骨合成的发现。这种革命性的技术能够对缺陷进行解剖固定,从而在不影响稳定性的情况下保持运动,这对于C1C2和C1C0关节的正常功能至关重要,这是一个主要优势。我们报告了一例54岁男性孤立性杰弗逊骨折的病例,并成功地采用该技术治疗。我们还概述了C1损伤的生物力学,并对复杂C1C2损伤的治疗方案进行了相关文献综述。
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引用次数: 0
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Journal of spine & neurosurgery
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