The journal of the American College of Clinical Wound Specialists最新文献

There are approximately 6.5 million patients in the U.S. suffering from chronic wounds and approximately 140,000 patients hospitalized every year with new wounds. With a long healing process, this demands the need for a non-contact, low cost, and remote monitoring solution that can assist clinicians in diagnosing and treating a patient's wound. This will reduce the burden of countless office visits, especially for those who are elderly and incapacitated. We present a mobile platform based wound 3D imaging app. The app is the only integrated measurement solution encompassing wound area and volume through low cost yet accurate 3D imaging. Extensive experiments show the app has 1.14% and 4.41% relative errors for wound area and volume measurement respectively, far exceeding currently employed clinic methods. In addition, non-invasive volume measurement methods currently use expensive industrial 3D (>$20K) cameras, but our solution provides cheap and accurate results.

The invasion of the skin and subcutaneous tissue by the larvae (Maggot) is known as Maggot infestation. It was found that farmers who are working in agricultural fields are more prone to this infestation. A case of 60 year old male patient with ulceration on leg for 10 days which was initially smaller and later developed into a larger wound, due to maggot larvae. This case report illustrates the importance and method of treating this cutaneous myiasis.

Despite advances in surgical technique, postoperative complications may lead to refractory cutaneous sinus tracts or tunnels. Negative pressure wound therapy is difficult to apply in longer tracts with a narrow diameter opening and conservative treatment failures ultimately necessitate surgical revisions. The aim of this pilot study was a clinical utility assessment of two different commercial placental membrane products for refractory cutaneous sinus tracts of surgical origin. Patients were treated with viable cryopreserved placental membrane (vCPM, n = 6) or devitalized dehydrated amnion/chorion membrane (dHACM, n = 6). The primary outcome measurement was the proportion of complete sinus tract depth resolution without exudate. Secondary endpoints included 4-week percent reduction in sinus tract probing depth and peri-tract wound surface area, days and number of grafts to resolution, number of wound-related infections, and 1-year recurrence rate for closed sinus tracts. All vCPM patients demonstrated complete sinus tract resolution compared to zero closures in the dHACM group (p = 0.00216). The vCPM group achieved greater percent reduction in probing depth (73.3 ± 21.9 versus −4.4 ± 91.3) and surrounding wound surface area (34.8 ± 86.8 versus −279.3 ± 454.9) at 4 weeks than dHACM. The use of viable intact cryopreserved placental membrane has demonstrated positive clinical outcomes for the treatment for refractory exudative sinus tracts and may be an alternative to repeat surgical intervention.

Oxidative stress is hypothesized to be one of the main causes of the pathophysiologic alterations observed during impaired healing of wounds. In the present study, we aimed to measure systemic levels of free radicals in blood and anti-oxidant (AO) activity in the plasma of patients with chronic ulcers (venous stasis ulcers and arterial insufficiency ulcers) of lower extremities (CULEs). Oxidants and AO activity were measured in eighty-five consecutive patients with CVSUs of the lower extremities as they arrived randomly for routine visits to our ambulatory clinic. Values of oxidant and AO status in patients with CULEs were significantly different from normal. No significant differences in oxidant and AO values were found between patients with arterial ulcers or those with venous ulcers. A significant difference was found in AO values of diabetic patients with chronic venous ulcers compared with non-diabetic patients with chronic venous ulcers. No significant differences were observed when evaluating oxidant/AO values and smoking habits. Precise reasons why the association of diabetes and venous (but not arterial) ulcers was correlated with defective AO status in plasma are not known. Other data were also intriguing: diminished AO activity was observed in female patients, no significant differences in oxidant and values were found between patients with arterial ulcers or those with venous ulcers, no significant correlation was found between age and oxidant, as well as no significant differences were observed when evaluating oxidant/AO values and smoking habits.