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Prevalence and treatment of perinatal anxiety: diagnostic interview study - ERRATUM.
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-23 DOI: 10.1192/bjo.2024.858
Susan Ayers, Andrea Sinesi, Rose Meades, Helen Cheyne, Margaret Maxwell, Catherine Best, Stacey McNicol, Louise R Williams, Una Hutton, Grace Howard, Judy Shakespeare, Fiona Alderdice, Julie Jomeen
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引用次数: 0
'If one doesn't happen, the other will': forensic mental health service patients' experiences of co-occurring self-harm and aggression. “如果一个不发生,另一个会发生”:法医心理健康服务患者同时发生自残和攻击的经历。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-22 DOI: 10.1192/bjo.2024.834
Matina Shafti, Peter Taylor, Andrew Forrester, Louise Robinson, Sandeep Mathews, Daniel Pratt

Background: Co-occurring self-harm and aggression (dual harm) is particularly prevalent among forensic mental health service (FMHS) patients. There is limited understanding of why this population engages in dual harm.

Aims: This work aims to explore FMHS patients' experiences of dual harm and how they make sense of this behaviour, with a focus on the role of emotions.

Method: Participants were identified from their participation in a previous study. Sixteen FMHS patients with a lifetime history of dual harm were recruited from two hospitals. Individuals participated in one-to-one, semi-structured interviews where they reflected on past and/or current self-harm and aggression. Interview transcripts were analysed using reflexive thematic analysis.

Results: Six themes were generated: self-harm and aggression as emotional regulation strategies, the consequences of witnessing harmful behaviours, relationships with others and the self, trapped within the criminal justice system, the convergence and divergence of self-harm and aggression, and moving forward as an FMHS patient. Themes highlighted shared risk factors of dual harm across participants, including emotional dysregulation, perceived lack of social support and witnessing harmful behaviours. Participants underlined the duality of their self-harm and aggression, primarily utilising both to regulate negative emotions. These behaviours also fulfilled distinct purposes at times (e.g. self-harm as punishment, aggression as defence). The impact of contextual factors within FMHSs, including restrictive practices and institutionalisation, were emphasised.

Conclusions: Findings provide recommendations that can help address dual harm within forensic settings, including (a) transdiagnostic, individualised approaches that consider the duality of self-harm and aggression; and (b) cultural and organisational focus on recovery-centred practice.

背景:在法医精神卫生服务(FMHS)患者中,同时发生的自我伤害和攻击(双重伤害)尤为普遍。人们对这一群体为何会受到双重伤害的理解有限。目的:本研究旨在探索FMHS患者的双重伤害经历,以及他们如何理解这种行为,重点关注情绪的作用。方法:参与者从之前的研究中被识别出来。从两家医院招募了16例终生有双重伤害史的FMHS患者。个人参加一对一的半结构化访谈,在那里他们反思过去和/或现在的自我伤害和攻击行为。访谈记录使用反身性主题分析进行分析。结果:产生了六个主题:自我伤害和攻击作为情绪调节策略,目睹有害行为的后果,与他人和自我的关系,陷入刑事司法系统,自我伤害和攻击的趋同和分歧,以及作为FMHS患者的前进。主题强调了参与者共同的双重伤害风险因素,包括情绪失调、感知到缺乏社会支持和目睹有害行为。参与者强调了他们的自我伤害和攻击性的两重性,主要利用两者来调节负面情绪。这些行为有时也会实现不同的目的(例如,自残作为惩罚,攻击作为防御)。强调了家庭保健服务内部环境因素的影响,包括限制性做法和制度化。结论:研究结果提供了有助于解决法医环境中的双重伤害的建议,包括:(a)考虑自我伤害和攻击的二元性的跨诊断、个性化方法;(b)注重以康复为中心的实践的文化和组织。
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引用次数: 0
Examining the association between maternal prenatal psychiatric disorders and behavioural problems among offspring in early childhood: population-based study. 检查母亲产前精神障碍与幼儿后代行为问题之间的关系:基于人群的研究。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-17 DOI: 10.1192/bjo.2024.839
Amy Braddon, Rosa Alati, Kim S Betts

Background: Exposure to maternal mental illness during foetal development may lead to altered development, resulting in permanent changes in offspring functioning.

Aims: To assess whether there is an association between prenatal maternal psychiatric disorders and offspring behavioural problems in early childhood, using linked health administrative data and the Australian Early Development Census from New South Wales, Australia.

Method: The sample included all mother-child pairs of children who commenced full-time school in 2009 in New South Wales, and met the inclusion criteria (N = 69 165). Univariable logistic regression analysis assessed unadjusted associations between categories of maternal prenatal psychiatric disorders with indicators of offspring behavioural problems. Multivariable logistic regression adjusted the associations of interest for psychiatric categories and a priori selected covariates. Sensitivity analyses included adjusting the final model for primary psychiatric diagnoses and assessing association of interest for effect modification by child's biological gender.

Results: Children exposed in the prenatal period to maternal psychiatric disorders had greater odds of being developmentally vulnerable in their first year of school. Children exposed to maternal anxiety disorders prenatally had the greatest odds for behavioural problems (adjusted odds ratio 1.98; 95% CI 1.43-2.69). A statistically significant interaction was found between child biological gender and prenatal hospital admissions for substance use disorders, for emotional subdomains, aggression and hyperactivity/inattention.

Conclusions: Children exposed to prenatal maternal mental illness had greater odds for behavioural problems, independent of postnatal exposure. Those exposed to prenatal maternal anxiety were at greatest risk, highlighting the need for targeted interventions for, and support of, families with mental illness.

背景:在胎儿发育期间暴露于母亲精神疾病可能导致发育改变,从而导致后代功能的永久性改变。目的:利用相关的健康管理数据和来自澳大利亚新南威尔士州的澳大利亚早期发展普查,评估产前母亲精神障碍与儿童早期行为问题之间是否存在关联。方法:样本包括2009年在新南威尔士州入读全日制学校的所有母子对儿童,符合纳入标准(N = 69 165)。单变量logistic回归分析评估了母亲产前精神障碍类别与后代行为问题指标之间未经调整的关联。多变量逻辑回归调整了精神病学类别和先验选择协变量的兴趣关联。敏感性分析包括调整初级精神病诊断的最终模型和评估儿童生理性别对效果改变的兴趣关联。结果:产前暴露于母亲精神疾病的儿童在入学第一年出现发育脆弱的几率更大。产前暴露于母亲焦虑症的儿童出现行为问题的几率最大(调整优势比1.98;95% ci 1.43-2.69)。儿童生理性别与产前住院治疗物质使用障碍、情绪子域、攻击性和多动/注意力不集中之间存在统计学上显著的相互作用。结论:暴露于产前母亲精神疾病的儿童有更大的可能性出现行为问题,与产后暴露无关。那些暴露于产前产妇焦虑的人面临的风险最大,这突出表明需要对患有精神疾病的家庭进行有针对性的干预和支持。
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引用次数: 0
Examining the effects of school-vacation transitions on depression and anxiety in adolescents: network analysis. 校假过渡对青少年抑郁和焦虑的影响:网络分析。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-17 DOI: 10.1192/bjo.2024.806
Yumeng Ju, Yumeng Yang, Rui Yuan, Yafei Chen, Junwu Liu, Wenwen Ou, Yunjing Li, Siqi Yang, Yimei Lu, Liang Li, Mei Huang, Mohan Ma, Guanyi Lv, Xiaotian Zhao, Yaqi Qing, Jin Liu, Yan Zhang

Background: The school-vacation cycle may have impacts on the psychological states of adolescents. However, little evidence illustrates how transition from school to vacation impacts students' psychological states (e.g. depression and anxiety).

Aims: To explore the changing patterns of depression and anxiety symptoms among adolescent students within a school-vacation transition and to provide insights for prevention or intervention targets.

Method: Social demographic data and depression and anxiety symptoms were measured from 1380 adolescent students during the school year (age: 13.8 ± 0.88) and 1100 students during the summer vacation (age: 14.2 ± 0.93) in China. Multilevel mixed-effect models were used to examine the changes in depression and anxiety levels and the associated influencing factors. Network analysis was used to explore the symptom network structures of depression and anxiety during school and vacation.

Results: Depression and anxiety symptoms significantly decreased during the vacation compared to the school period. Being female, higher age and with lower mother's educational level were identified as longitudinal risk factors. Interaction effects were found between group (school versus vacation) and the father's educational level as well as grade. Network analyses demonstrated that the anxiety symptoms, including 'Nervous', 'Control worry' and 'Relax' were the most central symptoms at both times. Psychomotor disturbance, including 'Restless', 'Nervous' and 'Motor', bridged depression and anxiety symptoms. The central and bridge symptoms showed variation across the school vacation.

Conclusions: The school-vacation transition had an impact on students' depression and anxiety symptoms. Prevention and intervention strategies for adolescents' depression and anxiety during school and vacation periods should be differentially developed.

背景:学校假期周期可能对青少年的心理状态有影响。然而,很少有证据表明从学校到假期的过渡如何影响学生的心理状态(如抑郁和焦虑)。目的:探讨学校假期过渡时期青少年学生抑郁、焦虑症状的变化规律,为预防和干预提供依据。方法:对全国1380名在校学生(年龄:13.8±0.88)和1100名暑假学生(年龄:14.2±0.93)的社会人口学资料和抑郁、焦虑症状进行测量。采用多水平混合效应模型检验抑郁和焦虑水平的变化及其相关影响因素。采用网络分析方法探讨在校和假期抑郁、焦虑的症状网络结构。结果:与在校期间相比,假期期间抑郁和焦虑症状明显减轻。女性、年龄较大和母亲受教育程度较低被确定为纵向危险因素。小组(学校与假期)与父亲的教育水平和年级之间存在交互作用。网络分析表明,焦虑症状,包括“紧张”、“控制担忧”和“放松”,在两个时间点都是最核心的症状。精神运动障碍,包括“不安”、“紧张”和“运动”,是抑郁和焦虑症状之间的桥梁。中心症状和桥状症状在学校假期期间有所不同。结论:校假过渡对学生抑郁和焦虑症状有影响。青少年在校期间和假期期间的抑郁和焦虑的预防和干预策略应有所区别。
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引用次数: 0
Experiences of eating disorder services for people caring for a loved one with an eating disorder in the UK: national survey. 在英国,为照顾患有饮食失调症的亲人提供饮食失调服务的经验:全国调查。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-17 DOI: 10.1192/bjo.2024.812
Hannah Cribben, Rachel Batchelor, Pamela Macdonald, Janet Treasure, Erica Cini, Dasha Nicholls, Carol Kan

Background: Research suggests that those caring for a loved one with an eating disorder in the UK report unmet needs and highlight areas for improvement. More research is needed to understand these experiences on a wider, national scale.

Aims: To disseminate a national survey for adults who had experience caring for a loved one with an eating disorder in the UK, informed by the findings of a smaller scale, qualitative study with parents, siblings and partners in the UK.

Method: A cross-sectional web-based survey was disseminated to adults who had experience caring for a loved one with an eating disorder in the UK.

Results: A total of 360 participants completed the survey. Participants described experiences of care received in both children and young people's, and adult services. Those receiving care from children and young people's services generally reported more timely care, greater involvement in care and more confidence managing their loved one's symptoms post-discharge. In both settings, participants identified a number of areas for improvement, including more timely access to care, improved transition processes and discharge planning, and increased involvement in their loved one's care.

Conclusions: This survey captures the experiences of individuals caring for a loved one with an eating disorder in the UK. There are identified discrepancies between experiences of care in children and young people services compared with adult services. Clinical implications and recommendations for improvement are discussed, including improved transition and discharge processes, increased involvement of and/or support for carers themselves, and more timely access to support services for the unwell individual.

背景:研究表明,在英国,那些照顾患有饮食失调症的亲人的人报告了未满足的需求,并强调了需要改进的地方。需要更多的研究来在更广泛的全国范围内了解这些经验。目的:通过对英国父母、兄弟姐妹和伴侣进行的小规模定性研究的结果,传播一项针对英国有过照顾患有饮食失调症的亲人经历的成年人的全国性调查。方法:在英国,一项基于网络的横断面调查被分发给有过照顾患有饮食失调症的亲人的经历的成年人。结果:共有360名参与者完成了调查。参与者描述了在儿童、青少年和成人服务机构接受照顾的经历。那些接受儿童和青少年服务机构护理的人通常报告说,他们得到的护理更及时,更积极地参与护理,更有信心处理他们所爱的人出院后的症状。在这两种情况下,参与者都确定了一些需要改进的领域,包括更及时地获得护理,改进过渡过程和出院计划,以及更多地参与他们所爱的人的护理。结论:这项调查记录了英国人照顾患有饮食失调症的亲人的经历。与成人服务相比,儿童和青少年服务的护理经历存在明显差异。讨论了临床意义和改进建议,包括改进过渡和出院流程,增加对护理人员本身的参与和/或支持,以及为身体不适的个人提供更及时的支持服务。
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引用次数: 0
The mental health impact of repeated COVID-19 enforced lockdowns in England: evidence from the UK Household Longitudinal Study. 英国COVID-19强制封锁对心理健康的影响:来自英国家庭纵向研究的证据。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-13 DOI: 10.1192/bjo.2024.803
Rashpal K Dhensa-Kahlon, Siu Tim Wan, Jacqueline A-M Coyle-Shapiro, Kevin Rui-Han Teoh

Background: Research shows initial COVID-19 lockdowns increased population mental distress. Yet, the mental health impact of repeated lockdowns in England remains unknown.

Aims: To: (a) explore changes in population mental health symptoms over the COVID-19 pandemic period (March 2020 to March 2021) in England, comparing this with trends from a decade before (2009-2019) as well as after (2021-2023); (b) compare the mental health impact of each of the three lockdowns in England with periods of eased restrictions, determining who was most affected; (c) examine the impact of demographics and distinct time periods on the prevalence of mental health symptoms.

Method: A secondary analysis of a national longitudinal cohort study, utilising data from Waves 1-13 of the UK Household Longitudinal Study and from Waves 1-9 of the COVID-19 Survey. Mental health was assessed using the 12-item General Health Questionnaire. Student t-tests and logistical regressions were conducted.

Results: There was a significant increase in the prevalence of self-reported symptoms of mental health during England's pandemic period, encompassing three lockdowns, compared with the average of rates from 10 years before. Rates of reported mental health symptoms were not significantly different across each lockdown, but were significantly higher than pre-pandemic rates, declining with eased restrictions. Rates from the end of lockdown to May 2023 revealed elevated mental health symptoms compared with pre-pandemic. Elevated symptoms were observed for women, people homeworking, those with health conditions, individuals aged 30-45 years and those experiencing loneliness.

Conclusion: Repeated lockdowns in England had a substantial impact on mental health, indicating requirements for ongoing mental health support.

背景:研究表明,最初的 COVID-19 封锁增加了人们的精神压力。然而,在英格兰反复封锁对心理健康的影响仍然未知。目的:(a) 探讨在 COVID-19 大流行期间(2020 年 3 月至 2021 年 3 月)英格兰人口精神健康症状的变化,并将其与十年前(2009-2019 年)和十年后(2021-2023 年)的趋势进行比较;(b) 比较英格兰三次封锁中的每一次封锁对精神健康的影响,以及放松限制的时期,确定哪些人受到的影响最大;(c) 研究人口统计学和不同时期对精神健康症状流行的影响:方法:利用英国家庭纵向研究第 1-13 波数据和 COVID-19 调查第 1-9 波数据,对一项全国纵向队列研究进行二次分析。心理健康采用 12 项一般健康问卷进行评估。进行了学生 t 检验和逻辑回归:结果:在英格兰大流行期间(包括三次封锁),自我报告的心理健康症状发生率与 10 年前的平均发生率相比大幅上升。在每次封锁期间,报告的精神健康症状发生率没有明显差异,但明显高于大流行前的发生率,并随着限制的放松而下降。与大流行前相比,从封锁结束到 2023 年 5 月的报告率显示精神健康症状有所上升。女性、在家工作的人、有健康问题的人、30-45 岁的人和经历孤独的人的症状都有所上升:结论:英格兰的多次封锁对心理健康产生了重大影响,表明需要持续的心理健康支持。
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引用次数: 0
Alcohol use among populations with autism spectrum disorder: narrative systematic review. 自闭症谱系障碍人群中的酒精使用:叙述性系统回顾。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-13 DOI: 10.1192/bjo.2024.824
William Barber, Betul Aslan, Tim Meynen, John Marsden, Samuel R Chamberlain, Vigneshwar Paleri, Julia M A Sinclair

Background: Alcohol use in autism spectrum disorder (ASD) is under-researched. Previous reviews have explored substance use as a whole, but this neglects individual characteristics unique to different substances. Alcohol use in non-clinical samples is associated with diverse responses. To advance practice and policy, an improved understanding of alcohol use among people with ASD is crucial to meet individual needs.

Aims: This was a narrative systematic review of the current literature on the association between alcohol use and ASD, focusing on aetiology (biological, psychological, social and environmental risk factors) and implications (consequences and protective factors) of alcohol use in autistic populations who utilise clinical services. We sought to identify priority research questions and offer policy and practice recommendations.

Method: PROSPERO Registration: CRD42023430291. The search was conducted across five databases: CINAHL, EMBASE, MEDLINE, PsychINFO and Global Health. Included studies explored alcohol use and ASD within clinical samples.

Results: A total of 22 studies was included in the final review. The pooled prevalence of alcohol use disorder in ASD was 1.6% and 16.1% in large population registers and clinical settings, respectively. Four components were identified as possible aetiological risk factors: age, co-occurring conditions, gender and genetics. We identified ten implications for co-occurring alcohol use disorder in ASD, summarised as a concept map.

Conclusion: Emerging trends in the literature suggest direction and principles for research and practice. Future studies should use a standardised methodological approach, including psychometrically validated instruments and representative samples, to inform policy and improve the experience for autistic populations with co-occurring alcohol use.

背景:自闭症谱系障碍(ASD)的酒精使用研究尚不充分。以前的评论从整体上探讨了物质使用,但这忽略了不同物质特有的个体特征。在非临床样本中,酒精使用与不同的反应有关。为了推进实践和政策,提高对ASD患者饮酒情况的了解对于满足个人需求至关重要。目的:这是对当前关于酒精使用与ASD之间关系的文献进行的叙述性系统综述,重点关注使用临床服务的自闭症人群中酒精使用的病因学(生物学、心理、社会和环境风险因素)和影响(后果和保护因素)。我们试图确定优先研究问题,并提供政策和实践建议。方法:PROSPERO注册:CRD42023430291。这项研究是在五个数据库中进行的:CINAHL、EMBASE、MEDLINE、PsychINFO和Global Health。包括在临床样本中探讨酒精使用和自闭症谱系障碍的研究。结果:共纳入22项研究。在大型人群登记和临床环境中,ASD中酒精使用障碍的总患病率分别为1.6%和16.1%。四个组成部分被确定为可能的病因危险因素:年龄、共同发生的条件、性别和遗传。我们确定了自闭症谱系障碍中同时发生的酒精使用障碍的10个含义,并将其总结为一个概念图。结论:文献中的新兴趋势为研究和实践提供了方向和原则。未来的研究应采用标准化的方法,包括心理计量学验证的工具和代表性样本,为政策提供信息,并改善同时发生酒精使用的自闭症人群的体验。
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引用次数: 0
Place of death and healthcare utilisation at the end of life among individuals with mental and behavioural disorders as underlying cause of death: population-level multiple-register study. 作为潜在死亡原因的精神和行为障碍个体的死亡地点和临终时的医疗保健利用情况:人口水平的多重登记研究。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2025-01-10 DOI: 10.1192/bjo.2024.821
Maja Magdalena Olsson, Christopher Holmberg, Cecilia Larsdotter, Stina Nyblom, Joakim Öhlén

Background: Understanding the place of death for individuals with mental and behavioural disorders (MBDs) is essential for identifying disparities in healthcare access and outcomes, as well as addressing broader health inequities within this population.

Aims: To examine the place of death among individuals in Sweden with the underlying cause of death reported as a MBD and compare variations between diagnostic groups, as well as explore associations between place of death and individual, sociodemographic and clinical factors.

Method: This population-level analysis used death certificate data (gender, age, underlying cause of death and place of death) recorded between 2013 and 2019 and other national register data. MBD group differences were compared using chi-square tests (χ2) and multinominal logistic regressions explored variations in place of death.

Results: The final sample consisted of 2875 individuals. Our regression model revealed that individuals with MBDs other than intellectual disabilities were less likely to die in hospitals (odds ratio 0.60-0.134 [95% CI = 0.014-0.651]) or care homes (odds ratio 0.11-0.97 [95% CI = 0.003-0.355]) than at home. Substance use disorders were the most common underlying cause of death (61.3%). This group consisted predominantly of men (78.8%, χ2, P < 0.001), and tended to be younger (χ2, P < 0.001).

Conclusions: Individuals with intellectual and developmental disabilities are more likely to die in hospitals or care homes than at home. Those with MBDs, particularly substance use disorders, face a high risk of premature death, highlighting gaps in healthcare and palliative care provision for these populations.

背景:了解精神和行为障碍(MBDs)患者的死亡地点对于确定医疗保健可及性和结果方面的差异以及解决这一人群中更广泛的卫生不平等至关重要。目的:检查瑞典人的死亡地点,并将潜在的死亡原因报告为MBD,比较诊断组之间的差异,以及探索死亡地点与个人、社会人口统计学和临床因素之间的关系。方法:使用2013年至2019年期间记录的死亡证明数据(性别、年龄、潜在死因和死亡地点)和其他国家登记数据进行人口水平分析。采用卡方检验(χ2)比较MBD组间差异,并采用多项逻辑回归分析死亡地点的差异。结果:最终样本为2875人。我们的回归模型显示,非智力残疾的mbd患者在医院(优势比0.60-0.134 [95% CI = 0.014-0.651])或疗养院(优势比0.11-0.97 [95% CI = 0.003-0.355])死亡的可能性低于在家。物质使用障碍是最常见的潜在死亡原因(61.3%)。该组以男性为主(78.8%,χ2, P < 0.001),且倾向于年轻化(χ2, P < 0.001)。结论:智力和发育障碍患者在医院或护理院死亡的可能性大于在家中死亡。mbd患者,特别是物质使用障碍患者,面临着过早死亡的高风险,这突出了这些人群在医疗保健和姑息治疗方面的差距。
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引用次数: 0
Differences associated with different prior mental disorders among earthquake-exposed treatment-seeking individuals. 地震暴露后寻求治疗的个体之间不同先前精神障碍的差异。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-27 DOI: 10.1192/bjo.2024.819
Cate F Woods, Virginia V W McIntosh, Christopher M Frampton, Frances A Carter, Helen C Colhoun, Jennifer Jordan, Rebekah A Smith, Caroline Bell

Background: History of prior mental disorder, particularly post-traumatic stress disorder (PTSD), increases risk for PTSD following subsequent trauma exposure. However, limited research has examined differences associated with specific prior mental disorders among people with PTSD.

Aims: The current study examined whether different prior mental disorders were associated with meaningful differences among individuals presenting to a specialist service for severe earthquake-related distress following the Canterbury earthquakes (N = 177).

Method: Two sets of comparisons were made: between participants with no history of prior disorder and participants with history of any prior disorder; and between participants with history of prior PTSD and those with history of other prior disorders. Comparisons were made in relation to sociodemographic factors, earthquake exposure, peri-traumatic distress, life events and current psychological functioning.

Results: Participants with any prior mental disorder had more current disorders than those with no prior disorder. Among participants with history of any prior disorder, those with prior PTSD reported more life events in the past 5 years than those with other prior disorders.

Conclusions: Findings suggest a history of any prior mental disorder contributes to increased clinical complexity, but not increased PTSD severity, among people with PTSD seeking treatment. Although post-disaster screening efforts should include those with prior mental disorders, it should also be recognised that those with no prior disorders are also at risk of developing equally severe PTSD.

背景:既往精神障碍史,特别是创伤后应激障碍(PTSD),会增加后续创伤暴露后发生PTSD的风险。然而,有限的研究已经检查了PTSD患者与特定先前精神障碍相关的差异。目的:目前的研究考察了在坎特伯雷地震后,不同的先前精神障碍是否与在严重地震相关痛苦专科服务中的个体有意义的差异相关(N = 177)。方法:进行两组比较:无既往障碍史和有既往障碍史的受试者;以及有创伤后应激障碍病史的参与者和有其他疾病病史的参与者之间的差异。比较了社会人口因素、地震暴露、创伤后痛苦、生活事件和当前心理功能。结果:有精神障碍的参与者比没有精神障碍的参与者有更多的当前障碍。在有任何先前疾病史的参与者中,有创伤后应激障碍的人在过去5年里报告的生活事件比有其他先前疾病的人多。结论:研究结果表明,在寻求治疗的PTSD患者中,任何先前的精神障碍史会增加临床复杂性,但不会增加PTSD的严重程度。虽然灾后筛查工作应该包括那些先前有精神障碍的人,但也应该认识到,那些之前没有精神障碍的人也有患同样严重的创伤后应激障碍的风险。
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引用次数: 0
Lost and found: dynamics of relationship and employment status over time in people with affective and psychotic spectrum disorders. 失而复得:情感和精神病谱系障碍患者的关系和就业状况随时间的动态变化。
IF 3.9 3区 医学 Q1 PSYCHIATRY Pub Date : 2024-12-26 DOI: 10.1192/bjo.2024.816
Fanny Senner, Lisa Kerkhoff, Kristina Adorjan, Michael Lauseker, Monika Budde, Maria Heilbronner, Janos L Kalman, Mojtaba Oraki Kohshour, Sergi Papiol, Daniela Reich-Erkelenz, Sabrina K Schaupp, Eva C Schulte, Thomas Vogl, Ion-George Anghelescu, Volker Arolt, Bernhardt T Baune, Udo Dannlowski, Nina Dalkner, Detlef E Dietrich, Andreas J Fallgatter, Christian Figge, Carsten Konrad, Fabian U Lang, Jens Reimer, Eva Z Reinighaus, Max Schmauß, Andrea Schmitt, Simon Senner, Carsten Spitzer, Jörg Zimmermann, Alkomiet Hasan, Peter Falkai, Thomas G Schulze, Urs Heilbronner, Sophie-Kathrin Greiner

Background: Employment and relationship are crucial for social integration. However, individuals with major psychiatric disorders often face challenges in these domains.

Aims: We investigated employment and relationship status changes among patients across the affective and psychotic spectrum - in comparison with healthy controls, examining whether diagnostic groups or functional levels influence these transitions.

Method: The sample from the longitudinal multicentric PsyCourse Study comprised 1260 patients with affective and psychotic spectrum disorders and 441 controls (mean age ± s.d., 39.91 ± 12.65 years; 48.9% female). Multistate models (Markov) were used to analyse transitions in employment and relationship status, focusing on transition intensities. Analyses contained multiple multistate models adjusted for age, gender, job or partner, diagnostic group and Global Assessment of Functioning (GAF) in different combinations to analyse the impact of the covariates on the hazard ratio of changing employment or relationship status.

Results: The clinical group had a higher hazard ratio of losing partner (hazard ratio 1.46, P < 0.001) and job (hazard ratio 4.18, P < 0.001) than the control group (corrected for age/gender). Compared with controls, clinical groups had a higher hazard of losing partner (affective group, hazard ratio 2.69, P = 0.003; psychotic group, hazard ratio 3.06, P = 0.001) and job (affective group, hazard ratio 3.43, P < 0.001; psychotic group, hazard ratio 4.11, P < 0.001). Adjusting for GAF, the hazard ratio of losing partner and job decreased in both clinical groups compared with controls.

Conclusion: Patients face an increased hazard of job loss and relationship dissolution compared with healthy controls, and this is partially conditioned by the diagnosis and functional level. These findings underscore a high demand for destigmatisation and support for individuals in managing their functional limitations.

背景:就业和关系对社会融合至关重要。然而,患有严重精神障碍的个体经常在这些领域面临挑战。目的:我们调查了情感和精神病谱系患者的就业和关系状态变化,并与健康对照进行比较,检查诊断组或功能水平是否影响这些转变。方法:来自纵向多中心心理病程研究的样本包括1260例情感性和精神谱系障碍患者和441例对照组(平均年龄±s.d, 39.91±12.65岁;48.9%的女性)。使用多状态模型(马尔科夫)来分析就业和关系状态的转变,重点关注转变强度。分析包含对年龄、性别、工作或伴侣、诊断组和整体功能评估(GAF)进行不同组合调整的多个多状态模型,以分析协变量对改变就业或关系状态的风险比的影响。结果:临床组失去伴侣的风险比(风险比1.46,P < 0.001)和工作的风险比(风险比4.18,P < 0.001)高于对照组(校正年龄/性别)。与对照组相比,临床组失去伴侣的风险更高(情感组,风险比2.69,P = 0.003;精神病组,风险比3.06,P = 0.001)和情感组,风险比3.43,P < 0.001;精神病组,风险比4.11,P < 0.001)。调整GAF后,与对照组相比,两个临床组失去伴侣和工作的风险比都下降了。结论:与健康对照组相比,患者面临更高的失业和关系破裂风险,这部分取决于诊断和功能水平。这些发现强调了消除歧视和支持个人管理其功能限制的高度需求。
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BJPsych Open
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