Background: Sarcopenia is a prevalent issue among older patients with hip fracture and is a risk factor for poor clinical outcomes. Computed tomography (CT)-derived muscle density and areawere reported to predict the prognosis of fracture patients. This study aimed to assess the efficacy of these CT-based muscle parameters in predicting 1-year mortality in the oldest-old patients with hip fracture (≥ 80 years).
Methods: A retrospective study was conducted on 324 hip fracture patients aged ≥ 80 years from 2018 to 2022. The cross-sectional area (CSA) and Hounsfield units (HU) of periarticular hip muscles were measured from CT images. The primary outcome was 1-year mortality. A multivariate logistic regression model was constructed, and its performance was assessed using ROC analysis, calibration curves, and Hosmer-Lemeshow testing. A nomogram was developed for model visualization and early clinical application.
Results: The 1-year mortality rate in this cohort was 13.0% (42/324). Survivors and non-survivors significantly differed in age, red blood cells (RBC), platelets, albumin, urea, and gluteal muscle parameters (all P < 0.05). Multivariate analysis identified four mortality predictors: older age (P = 0.048), lower albumin (P = 0.025), reduced gluteal density (P = 0.031), and smaller muscle area (P = 0.045). Gluteus maximus density and area independently predicted 1-year mortality (P < 0.05) in oldest-old hip fracture patients. Our predictive model incorporating age, muscle density, albumin, and muscle area showed a moderate predictive value (AUC = 0.741).
Conclusion: This CT-based method offers a practical alternative to traditional sarcopenia assessments, facilitating early risk identification in this hip fracture population.
{"title":"Gluteus maximus cross-sectional area/density in 1-year mortality prediction for oldest-old hip fracture patients.","authors":"Mingyuan Song, Tian Xie, Renwang Sheng, Mumin Cao, Yucheng Gao, Chuwei Tian, Jinyu Wang, Yingjuan Li, Wei Gao, Yunfeng Rui","doi":"10.1186/s12877-026-07116-3","DOIUrl":"https://doi.org/10.1186/s12877-026-07116-3","url":null,"abstract":"<p><strong>Background: </strong>Sarcopenia is a prevalent issue among older patients with hip fracture and is a risk factor for poor clinical outcomes. Computed tomography (CT)-derived muscle density and areawere reported to predict the prognosis of fracture patients. This study aimed to assess the efficacy of these CT-based muscle parameters in predicting 1-year mortality in the oldest-old patients with hip fracture (≥ 80 years).</p><p><strong>Methods: </strong>A retrospective study was conducted on 324 hip fracture patients aged ≥ 80 years from 2018 to 2022. The cross-sectional area (CSA) and Hounsfield units (HU) of periarticular hip muscles were measured from CT images. The primary outcome was 1-year mortality. A multivariate logistic regression model was constructed, and its performance was assessed using ROC analysis, calibration curves, and Hosmer-Lemeshow testing. A nomogram was developed for model visualization and early clinical application.</p><p><strong>Results: </strong>The 1-year mortality rate in this cohort was 13.0% (42/324). Survivors and non-survivors significantly differed in age, red blood cells (RBC), platelets, albumin, urea, and gluteal muscle parameters (all P < 0.05). Multivariate analysis identified four mortality predictors: older age (P = 0.048), lower albumin (P = 0.025), reduced gluteal density (P = 0.031), and smaller muscle area (P = 0.045). Gluteus maximus density and area independently predicted 1-year mortality (P < 0.05) in oldest-old hip fracture patients. Our predictive model incorporating age, muscle density, albumin, and muscle area showed a moderate predictive value (AUC = 0.741).</p><p><strong>Conclusion: </strong>This CT-based method offers a practical alternative to traditional sarcopenia assessments, facilitating early risk identification in this hip fracture population.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146148887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-09DOI: 10.1186/s12877-026-07024-6
Hannah Commins, Grace E Vincent, Madeline Sprajcer, Rosemary Gibson, Kate Vincent, Spencer S H Roberts, Alexandra E Shriane, Patrick J Owen
{"title":"How do night-time awakenings, assistive technologies, and help-seeking behaviors impact the sleep of Australian carers? A cross-sectional study.","authors":"Hannah Commins, Grace E Vincent, Madeline Sprajcer, Rosemary Gibson, Kate Vincent, Spencer S H Roberts, Alexandra E Shriane, Patrick J Owen","doi":"10.1186/s12877-026-07024-6","DOIUrl":"https://doi.org/10.1186/s12877-026-07024-6","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146148812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Development and validation of a risk prediction model for oral frailty among Chinese older adults with type 2 diabetes mellitus.","authors":"Wenjuan Yang, Kangqin Cai, Cheng Zhang, Peimin Zhuang, Qin Pan, Qingfang Lin, Liping Yang, Juan He, Xia Zhang, Junna Wang, Daiying Jing, Meng Fang, Jiquan Zhang","doi":"10.1186/s12877-026-07039-z","DOIUrl":"https://doi.org/10.1186/s12877-026-07039-z","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146141090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-09DOI: 10.1186/s12877-026-07010-y
Jackie Hoi Man Chan, Ken Hok Man Ho, Helen Yue Lai Chan
{"title":"A videoconferencing group-based psychoeducation for family caregivers of people living with dementia: a feasibility study.","authors":"Jackie Hoi Man Chan, Ken Hok Man Ho, Helen Yue Lai Chan","doi":"10.1186/s12877-026-07010-y","DOIUrl":"https://doi.org/10.1186/s12877-026-07010-y","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146148805","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
<p><strong>Background: </strong>Frailty in older adults is a common aging-related syndrome that can lead to adverse health outcomes. Although physical exercise and nutritional interventions have been widely recognized as beneficial for managing frailty, the comparative effectiveness of various intervention approaches remains uncertain.</p><p><strong>Objective: </strong>We systematically evaluated the effects of multicomponent exercise, nutritional supplementation, and combined interventions on frailty status and functional outcomes in older adults using network meta-analysis.</p><p><strong>Methods: </strong>Randomized controlled trials (RCTs) published between 2006 and 2025 were searched to include studies assessing the effects of multicomponent exercise, nutritional supplements (including amino acids and proteins, etc.), combined interventions, or standard care on frailty status in older adults aged ≥ 60 years. Changes in frailty scores constituted the primary outcome. Secondary outcomes comprised gait speed, the Short Physical Performance Battery (SPPB), and the Timed Up-and-Go test (TUG). Effect sizes were calculated using Standardized Mean Difference (SMD) and 95% Confidence Interval (CI), and ranked using network meta-analysis.</p><p><strong>Results: </strong>Ultimately, 22 RCTs involving 2,055 participants were included, with comparable baseline characteristics among participants. Regarding the improvement in frailty scores, combined interventions demonstrated the greatest improvement (SMD = -0.92, 95% CI: -1.43 to -0.40), followed by multicomponent exercise (SMD = -0.78, 95% CI: -1.15 to -0.43), while nutritional supplementation showed a trend toward improvement that did not reach statistical significance (SMD = -0.69, 95% CI: -1.67 to 0.27). For gait speed, nutritional supplementation (SMD = + 0.37, 95% CI: +0.06 to + 0.68) yielded the greatest improvement, while multicomponent exercise (SMD = + 0.09, 95% CI: -0.04 to + 0.22) showed minimal benefit. Significant improvement in SPPB scores was observed only after multicomponent exercise (SMD = + 1.85, 95% CI: +0.33 to + 3.50). In the TUG test, combined interventions (SMD = -4.61, 95% CI: -9.36 to + 0.25) tended to reduce completion time (non-significant); conversely, multicomponent exercise alone significantly increased time (SMD = + 3.96 s, 95% CI: +0.91 to + 7.07). Low heterogeneity was observed across outcomes with no evidence of publication bias.</p><p><strong>Conclusion: </strong>The impacts of different interventions on frailty in older adults exhibited outcome-specific variations. Combined interventions were most effective in improving frailty scores, demonstrating potential synergistic effects between physical exercise and nutrition, while nutritional supplementation showed the most significant benefit for gait speed. Multicomponent exercise alone also produced significant improvements in frailty scores and physical performance. These findings suggest that clinicians should consider
{"title":"Effect of multicomponent exercise and nutrition intervention on frailty status in older adults: a network meta-analysis.","authors":"HongXia Yang, BiQing Wang, Qian Wang, JunNan Zhao, FeiFei Liu, XiaoLei Xie, FengQin Xu, Ping Zhang","doi":"10.1186/s12877-026-07111-8","DOIUrl":"https://doi.org/10.1186/s12877-026-07111-8","url":null,"abstract":"<p><strong>Background: </strong>Frailty in older adults is a common aging-related syndrome that can lead to adverse health outcomes. Although physical exercise and nutritional interventions have been widely recognized as beneficial for managing frailty, the comparative effectiveness of various intervention approaches remains uncertain.</p><p><strong>Objective: </strong>We systematically evaluated the effects of multicomponent exercise, nutritional supplementation, and combined interventions on frailty status and functional outcomes in older adults using network meta-analysis.</p><p><strong>Methods: </strong>Randomized controlled trials (RCTs) published between 2006 and 2025 were searched to include studies assessing the effects of multicomponent exercise, nutritional supplements (including amino acids and proteins, etc.), combined interventions, or standard care on frailty status in older adults aged ≥ 60 years. Changes in frailty scores constituted the primary outcome. Secondary outcomes comprised gait speed, the Short Physical Performance Battery (SPPB), and the Timed Up-and-Go test (TUG). Effect sizes were calculated using Standardized Mean Difference (SMD) and 95% Confidence Interval (CI), and ranked using network meta-analysis.</p><p><strong>Results: </strong>Ultimately, 22 RCTs involving 2,055 participants were included, with comparable baseline characteristics among participants. Regarding the improvement in frailty scores, combined interventions demonstrated the greatest improvement (SMD = -0.92, 95% CI: -1.43 to -0.40), followed by multicomponent exercise (SMD = -0.78, 95% CI: -1.15 to -0.43), while nutritional supplementation showed a trend toward improvement that did not reach statistical significance (SMD = -0.69, 95% CI: -1.67 to 0.27). For gait speed, nutritional supplementation (SMD = + 0.37, 95% CI: +0.06 to + 0.68) yielded the greatest improvement, while multicomponent exercise (SMD = + 0.09, 95% CI: -0.04 to + 0.22) showed minimal benefit. Significant improvement in SPPB scores was observed only after multicomponent exercise (SMD = + 1.85, 95% CI: +0.33 to + 3.50). In the TUG test, combined interventions (SMD = -4.61, 95% CI: -9.36 to + 0.25) tended to reduce completion time (non-significant); conversely, multicomponent exercise alone significantly increased time (SMD = + 3.96 s, 95% CI: +0.91 to + 7.07). Low heterogeneity was observed across outcomes with no evidence of publication bias.</p><p><strong>Conclusion: </strong>The impacts of different interventions on frailty in older adults exhibited outcome-specific variations. Combined interventions were most effective in improving frailty scores, demonstrating potential synergistic effects between physical exercise and nutrition, while nutritional supplementation showed the most significant benefit for gait speed. Multicomponent exercise alone also produced significant improvements in frailty scores and physical performance. These findings suggest that clinicians should consider","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146148829","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-07DOI: 10.1186/s12877-026-06997-8
Bolin Fan, Roujia Lin, Vivian W Q Lou, Janet Hui-Wen Hsiao, Jacqueline K Yuen, Hector Wing Hong Tsang, Jennifer Yee Man Tang
{"title":"Ambivalence in decision making for outdoor mobility among adult child carers of people with dementia: a study protocol for a randomized vignette study with message framing and eye-tracking.","authors":"Bolin Fan, Roujia Lin, Vivian W Q Lou, Janet Hui-Wen Hsiao, Jacqueline K Yuen, Hector Wing Hong Tsang, Jennifer Yee Man Tang","doi":"10.1186/s12877-026-06997-8","DOIUrl":"https://doi.org/10.1186/s12877-026-06997-8","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146130697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-07DOI: 10.1186/s12877-025-06720-z
Izzet Camcıoglu, Sönmez Sağlam, Mücahid Osman Yücel
{"title":"The effect of the preferred anesthesia method on early postoperative outcomes in elderly patients with hip fractures; a retrospective three-way comparative study.","authors":"Izzet Camcıoglu, Sönmez Sağlam, Mücahid Osman Yücel","doi":"10.1186/s12877-025-06720-z","DOIUrl":"https://doi.org/10.1186/s12877-025-06720-z","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-07DOI: 10.1186/s12877-026-07135-0
Yijie Wang, Jinyi Lang, Yikunxiao Meng, Weiheng Sun, Yutian Wei, Jialiang Liu, Qiong Wu, Bin Hu
{"title":"The impact of community participation on depression among empty nesters in China.","authors":"Yijie Wang, Jinyi Lang, Yikunxiao Meng, Weiheng Sun, Yutian Wei, Jialiang Liu, Qiong Wu, Bin Hu","doi":"10.1186/s12877-026-07135-0","DOIUrl":"https://doi.org/10.1186/s12877-026-07135-0","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146131007","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2026-02-07DOI: 10.1186/s12877-026-07007-7
Luyi Xu, Tingting Lin, Zheng Wang, Siyi Su, Jufang Li, Ping Li
{"title":"Latent profiles of attitudes toward ageing during the nursing home \"early transition period\" and its correlation with quality of life.","authors":"Luyi Xu, Tingting Lin, Zheng Wang, Siyi Su, Jufang Li, Ping Li","doi":"10.1186/s12877-026-07007-7","DOIUrl":"https://doi.org/10.1186/s12877-026-07007-7","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":" ","pages":""},"PeriodicalIF":3.8,"publicationDate":"2026-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146137473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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