Pub Date : 2025-01-03DOI: 10.1186/s12877-024-05421-3
Iany Tâmilla Pereira Batista, Keviny Magalhães Queiroz, Carlos Eduardo de Souza Menezes, Arnaldo Aires Peixoto Junior, Edgar Marçal
Background: Population aging and the increase in memory-related diseases have motivated the search for accessible cognitive screening instruments. To develop a digital memory and learning test (DMLT) based on Rey's Auditory Verbal Learning Test (RAVLT) principles to assess cognition in the elderly and identify early cognitive decline.
Methods: The research was divided into two phases: developing the digital test and the experimental phase of comparison with a reference test. The test was designed to assess episodic declarative memory through auditory-verbal learning. The experimental procedure involved 18 elderly participants and aimed to compare the performance on the digital test with the traditional RAVLT, followed by an evaluation of participant satisfaction.
Results: Performance on the digital test and the RAVLT was comparable, with no significant statistical differences, indicating convergent validity between the instruments. Electroencephalographic activity analyses revealed correlations between wave patterns and test performance, suggesting that the digital test may provide additional insights into the neurophysiological processes underlying cognitive performance. Satisfaction assessment revealed high participant acceptance.
Conclusion: The DMLT is a promising tool for cognitive assessment in the elderly, offering an accessible alternative. The high acceptance among elderly participants suggests that the test has potential for clinical and research use, although further studies are needed to validate its effectiveness in broader clinical settings.
背景:人口老龄化和记忆相关疾病的增加促使人们寻找可获得的认知筛查工具。基于Rey’s Auditory Verbal learning test (RAVLT)原理,开发一种数字记忆与学习测试(DMLT)来评估老年人的认知能力并识别早期认知衰退。方法:研究分为两个阶段:开发数字测试和与参考测试比较的实验阶段。该测试旨在通过听-语学习来评估情景陈述性记忆。实验过程涉及18名老年参与者,旨在比较数字测试与传统RAVLT的表现,然后评估参与者的满意度。结果:数字测试和RAVLT的性能具有可比性,没有显著的统计学差异,表明仪器之间的收敛效度。脑电图活动分析揭示了脑电波模式与测试表现之间的相关性,表明数字测试可能为认知表现背后的神经生理过程提供额外的见解。满意度评估显示参与者接受度高。结论:DMLT是一种很有前途的老年人认知评估工具,提供了一种可获得的替代方法。老年参与者的高接受度表明该测试具有临床和研究应用的潜力,尽管需要进一步的研究来验证其在更广泛的临床环境中的有效性。
{"title":"Development of a digital memory and learning test for elderly individuals.","authors":"Iany Tâmilla Pereira Batista, Keviny Magalhães Queiroz, Carlos Eduardo de Souza Menezes, Arnaldo Aires Peixoto Junior, Edgar Marçal","doi":"10.1186/s12877-024-05421-3","DOIUrl":"10.1186/s12877-024-05421-3","url":null,"abstract":"<p><strong>Background: </strong>Population aging and the increase in memory-related diseases have motivated the search for accessible cognitive screening instruments. To develop a digital memory and learning test (DMLT) based on Rey's Auditory Verbal Learning Test (RAVLT) principles to assess cognition in the elderly and identify early cognitive decline.</p><p><strong>Methods: </strong>The research was divided into two phases: developing the digital test and the experimental phase of comparison with a reference test. The test was designed to assess episodic declarative memory through auditory-verbal learning. The experimental procedure involved 18 elderly participants and aimed to compare the performance on the digital test with the traditional RAVLT, followed by an evaluation of participant satisfaction.</p><p><strong>Results: </strong>Performance on the digital test and the RAVLT was comparable, with no significant statistical differences, indicating convergent validity between the instruments. Electroencephalographic activity analyses revealed correlations between wave patterns and test performance, suggesting that the digital test may provide additional insights into the neurophysiological processes underlying cognitive performance. Satisfaction assessment revealed high participant acceptance.</p><p><strong>Conclusion: </strong>The DMLT is a promising tool for cognitive assessment in the elderly, offering an accessible alternative. The high acceptance among elderly participants suggests that the test has potential for clinical and research use, although further studies are needed to validate its effectiveness in broader clinical settings.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"3"},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697838/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926463","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correction: Fear of falling and its related factors in older adults following a fall in Kashan, Iran (2023-2024).","authors":"Fatemeh Sadat Izadi-Avanji, Azade Safa, Masoumeh Abedzadeh-Kalahroudi, Negin Shaterian","doi":"10.1186/s12877-024-05663-1","DOIUrl":"10.1186/s12877-024-05663-1","url":null,"abstract":"","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"5"},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Cognitive impairment is a common health problem among older adults. Previous studies have proven the association between sleep quality and cognitive impairment, but the specific underlying mechanisms need to be further explored. This study aimed to examine the relationship between sleep quality and cognitive impairment and the mediating effect of frailty in this relationship among the rural older adults.
Methods: Data from a cross-sectional study conducted in rural areas of Shandong Province from September to December in 2023. A total of 695 rural older adults were included. The Pittsburgh Sleep Quality Index (PSQI) was used to measure sleep quality. Frailty was defined using the FRAIL scale. We assessed cognitive impairment using the Dementia Screening Interview (AD8). Logistic regression analyse was used to assess the relationship between sleep quality and cognitive impairment. And the Karlson-Holm-Breen (KHB) method was performed to test the mediating role of frailty in this relationship.
Results: After adjusting for all covariates, sleep quality was significantly associated with cognitive impairment (OR = 1.047, 95% CI: 1.005-1.090). Frailty mediated the relationship between sleep quality and cognitive impairment, with a mediation effect value of 0.010 (95% CI: 0.001-0.020), accounting for 17.86% of the total effect.
Conclusions: We found there was an association between sleep quality and cognitive impairment, and frailty mediated the above relationship. Comprehensive intervention measures should be taken to reduce the incidence of frailty in the older adults and to improve their sleep quality, thereby preventing and delaying the occurrence and development of cognitive impairment.
{"title":"Frailty as a mediator between sleep quality and cognitive impairment among the rural older adults: a cross-sectional study.","authors":"Ping Dong, Cheng Cheng, Wenqiang Yin, Ziyuan Li, Yongli Shi, Min Gao, Xiaona Li, Dongping Ma, Hongwei Guo, Yan Wei, Zhongming Chen","doi":"10.1186/s12877-024-05657-z","DOIUrl":"10.1186/s12877-024-05657-z","url":null,"abstract":"<p><strong>Background: </strong>Cognitive impairment is a common health problem among older adults. Previous studies have proven the association between sleep quality and cognitive impairment, but the specific underlying mechanisms need to be further explored. This study aimed to examine the relationship between sleep quality and cognitive impairment and the mediating effect of frailty in this relationship among the rural older adults.</p><p><strong>Methods: </strong>Data from a cross-sectional study conducted in rural areas of Shandong Province from September to December in 2023. A total of 695 rural older adults were included. The Pittsburgh Sleep Quality Index (PSQI) was used to measure sleep quality. Frailty was defined using the FRAIL scale. We assessed cognitive impairment using the Dementia Screening Interview (AD8). Logistic regression analyse was used to assess the relationship between sleep quality and cognitive impairment. And the Karlson-Holm-Breen (KHB) method was performed to test the mediating role of frailty in this relationship.</p><p><strong>Results: </strong>After adjusting for all covariates, sleep quality was significantly associated with cognitive impairment (OR = 1.047, 95% CI: 1.005-1.090). Frailty mediated the relationship between sleep quality and cognitive impairment, with a mediation effect value of 0.010 (95% CI: 0.001-0.020), accounting for 17.86% of the total effect.</p><p><strong>Conclusions: </strong>We found there was an association between sleep quality and cognitive impairment, and frailty mediated the above relationship. Comprehensive intervention measures should be taken to reduce the incidence of frailty in the older adults and to improve their sleep quality, thereby preventing and delaying the occurrence and development of cognitive impairment.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"7"},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697922/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: A scarcity of data exists concerning atrial fibrillation (AF) during the perioperative stage of non-cardiothoracic surgery, particularly orthopedic surgery. In addition, given the frequency and significant impact of AF in the perioperative period, therefore our aim was to identify prognosis and predictors of elderly hip fracture patients with perioperative AF.
Methods: An examination of hip fracture patients at the Third Hospital of Hebei Medical University, who had been hospitalized from January 2018 to October 2020 in succession, was conducted retrospectively. To determine independent risk factors for paroxysmal AF in elderly hip fracture patients, univariate and multivariate logistic regression analysis were employed. The Kaplan-Meier survival curve demonstrated the correlation between all-cause mortality in the non-AF, paroxysmal AF, and permanent AF groups. An assessment of the correlation between baseline factors, complications, and all-cause mortality was conducted through univariable and multivariable Cox proportional hazards analysis.
Results: Enrolling 1,376 elderly patients with hip fractures, we found 1,189 in the non-AF group, 103 in the paroxysmal AF group, and 84 in the permanent AF group. Kaplan-Meier survival curves revealed a significantly lower overall survival rate in elderly hip fracture patients with AF, especially permanent AF. Based on COX regression analysis, we found that the main risk factors for all-cause death in elderly hip fracture patients with AF were concomitant pulmonary infection(HR 2.006,95%CI 1.019-3.949, P = 0.044), hyponatremia(HR 2.417,95%CI 1.177-4.961, P = 0.016), permanent AF(HR 2.806, 95%CI 1.036-4.198, P = 0.039). Independent risk factors for perioperative paroxysmal AF in elderly hip fracture patients were hypertension(OR 2.248, 95% CI 1.415-3.571, P = 0.001), COPD(OR 4.694, 95% CI 2.207-9.980, P < 0.001) and ACCI(OR 1.436, 95%CI 1.072-1.924, P = 0.015).
Conclusions: The mortality risk is high in elderly patients with hip fractures combined with AF. The independent risk factors for their death include permanent AF, pulmonary infection and hyponatremia. The independent risk factors for perioperative paroxysmal AF in elderly patients with hip fractures are ACCI, hypertension and COPD. we should identify risk factors and optimize the treatment plan at an early stage.
背景:关于非心胸外科手术,特别是骨科手术围手术期心房颤动(AF)的资料缺乏。此外,考虑到房颤在围手术期发生的频率和显著影响,因此我们的目的是确定老年髋部骨折围手术期患者的预后和预测因素。方法:回顾性分析河北医科大学第三医院2018年1月至2020年10月连续住院的髋部骨折患者。为了确定老年髋部骨折患者阵发性房颤的独立危险因素,采用单因素和多因素logistic回归分析。Kaplan-Meier生存曲线显示了非房颤、阵发性房颤和永久性房颤组全因死亡率之间的相关性。通过单变量和多变量Cox比例风险分析评估基线因素、并发症和全因死亡率之间的相关性。结果:共纳入1376例老年髋部骨折患者,其中非房颤组1189例,阵发性房颤组103例,永久性房颤组84例。Kaplan-Meier生存曲线显示老年髋部骨折合并房颤患者的总生存率明显降低,尤其是永久性房颤。基于COX回归分析,我们发现老年髋部骨折合并房颤患者全因死亡的主要危险因素为合并肺部感染(HR 2.006,95%CI 1.019-3.949, P = 0.044)、低钠血症(HR 2.417,95%CI 1.117 -4.961, P = 0.016)、永久性房颤(HR 2.806, 95%CI 1.036-4.198, P = 0.039)。老年髋部骨折患者围手术期发作性房颤的独立危险因素为高血压(OR 2.248, 95% CI 1.415 ~ 3.571, P = 0.001)、COPD(OR 4.694, 95% CI 2.207 ~ 9.980, P)。结论:老年髋部骨折合并房颤患者死亡风险较高,其死亡的独立危险因素为永久性房颤、肺部感染和低钠血症。老年髋部骨折患者围手术期阵发性房颤的独立危险因素为ACCI、高血压和COPD。我们应该及早识别危险因素,优化治疗方案。
{"title":"Predictors and prognosis of elderly hip fracture patients with perioperative atrial fibrillation: a nested case-control study.","authors":"Wei Li, Aoying Min, Wei Zhao, Weining Li, Shuhan Li, Saidi Ran, Mingming Fu, Qili Yu, Junkai Kou, Zhiqian Wang, Zhiyong Hou","doi":"10.1186/s12877-024-05647-1","DOIUrl":"10.1186/s12877-024-05647-1","url":null,"abstract":"<p><strong>Background: </strong>A scarcity of data exists concerning atrial fibrillation (AF) during the perioperative stage of non-cardiothoracic surgery, particularly orthopedic surgery. In addition, given the frequency and significant impact of AF in the perioperative period, therefore our aim was to identify prognosis and predictors of elderly hip fracture patients with perioperative AF.</p><p><strong>Methods: </strong>An examination of hip fracture patients at the Third Hospital of Hebei Medical University, who had been hospitalized from January 2018 to October 2020 in succession, was conducted retrospectively. To determine independent risk factors for paroxysmal AF in elderly hip fracture patients, univariate and multivariate logistic regression analysis were employed. The Kaplan-Meier survival curve demonstrated the correlation between all-cause mortality in the non-AF, paroxysmal AF, and permanent AF groups. An assessment of the correlation between baseline factors, complications, and all-cause mortality was conducted through univariable and multivariable Cox proportional hazards analysis.</p><p><strong>Results: </strong>Enrolling 1,376 elderly patients with hip fractures, we found 1,189 in the non-AF group, 103 in the paroxysmal AF group, and 84 in the permanent AF group. Kaplan-Meier survival curves revealed a significantly lower overall survival rate in elderly hip fracture patients with AF, especially permanent AF. Based on COX regression analysis, we found that the main risk factors for all-cause death in elderly hip fracture patients with AF were concomitant pulmonary infection(HR 2.006,95%CI 1.019-3.949, P = 0.044), hyponatremia(HR 2.417,95%CI 1.177-4.961, P = 0.016), permanent AF(HR 2.806, 95%CI 1.036-4.198, P = 0.039). Independent risk factors for perioperative paroxysmal AF in elderly hip fracture patients were hypertension(OR 2.248, 95% CI 1.415-3.571, P = 0.001), COPD(OR 4.694, 95% CI 2.207-9.980, P < 0.001) and ACCI(OR 1.436, 95%CI 1.072-1.924, P = 0.015).</p><p><strong>Conclusions: </strong>The mortality risk is high in elderly patients with hip fractures combined with AF. The independent risk factors for their death include permanent AF, pulmonary infection and hyponatremia. The independent risk factors for perioperative paroxysmal AF in elderly patients with hip fractures are ACCI, hypertension and COPD. we should identify risk factors and optimize the treatment plan at an early stage.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"4"},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697886/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926469","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-03DOI: 10.1186/s12877-024-05658-y
Yuet Yi Hung, Wang Yee Chu, Juming Jiang, Wing Yiu Yeung, Wing Huen Yan, Tai On Kwok, Yau Kei Chan
Background: The prevalence of age-related eye disorders is increasing with the aging of the global population. Community-based visual health education for the elderly has become a crucial intervention. With the advancement of technology, the application of extended reality (XR), such as virtual reality (VR) and augmented reality (AR), in health education has become more popular. This study aims to assess the effectiveness of educating the elderly about common age-related eye disorders through a novel AR-based health education workshop.
Methods: An AR-based education workshop was designed for the elderly to understand the major visual symptoms of several eye diseases and experience the challenges faced by visually impaired people. The effectiveness of the workshop was assessed by conducting pre- and post-activity surveys to measure the knowledge acquisition of the participants from this workshop.
Results: The intervention was found to significantly improve knowledge of age-related eye diseases among the elderly, while the participants' age and education level could influence the effectiveness of their knowledge gained from the workshop.
Conclusions: Our study revealed the potential of the use of AR technology in facilitating health education on eye diseases in the elderly. The specific backgrounds and characteristics of target participants and the combination of AR with other pedagogical approaches warrant further investigation to maximize the impact of AR-based workshops in health education in broader healthcare contexts.
{"title":"The interactive use of augmented reality for educating the elderly on common age-related eye disease.","authors":"Yuet Yi Hung, Wang Yee Chu, Juming Jiang, Wing Yiu Yeung, Wing Huen Yan, Tai On Kwok, Yau Kei Chan","doi":"10.1186/s12877-024-05658-y","DOIUrl":"10.1186/s12877-024-05658-y","url":null,"abstract":"<p><strong>Background: </strong>The prevalence of age-related eye disorders is increasing with the aging of the global population. Community-based visual health education for the elderly has become a crucial intervention. With the advancement of technology, the application of extended reality (XR), such as virtual reality (VR) and augmented reality (AR), in health education has become more popular. This study aims to assess the effectiveness of educating the elderly about common age-related eye disorders through a novel AR-based health education workshop.</p><p><strong>Methods: </strong>An AR-based education workshop was designed for the elderly to understand the major visual symptoms of several eye diseases and experience the challenges faced by visually impaired people. The effectiveness of the workshop was assessed by conducting pre- and post-activity surveys to measure the knowledge acquisition of the participants from this workshop.</p><p><strong>Results: </strong>The intervention was found to significantly improve knowledge of age-related eye diseases among the elderly, while the participants' age and education level could influence the effectiveness of their knowledge gained from the workshop.</p><p><strong>Conclusions: </strong>Our study revealed the potential of the use of AR technology in facilitating health education on eye diseases in the elderly. The specific backgrounds and characteristics of target participants and the combination of AR with other pedagogical approaches warrant further investigation to maximize the impact of AR-based workshops in health education in broader healthcare contexts.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"6"},"PeriodicalIF":3.4,"publicationDate":"2025-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697621/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142926397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1186/s12877-024-05615-9
Lay Khoon Lau, Penny Lun, Jonathan Gao, Edward Tan, Yew Yoong Ding
Background: Comprehensive Geriatric Assessment is the gold standard of clinical care for older patients but its application in the primary care setting is limited, possibly due to its time-consuming process. Hence, a brief geriatric assessment could be a feasible alternative. We conducted a scoping review to identify which brief geriatric assessment tools have been evaluated or implemented in primary and community care settings and to identify the domains assessed including their reported outcomes.
Methods: CENTRAL, PubMed and Embase were searched using specific text words and MeSH for articles published from inception that studied evaluation or implementation of brief geriatric assessments in primary care or community setting.
Results: Twenty-five articles were included in the review, of which 11 described brief geriatric assessments implemented in community, nine in primary care and five in mixed settings. Physical health, functional, mobility/balance and psychological/mental emerged as four domains that are most assessed in brief geriatric assessments. Self-reported questionnaire is the key approach, but uncertainty remains on the validity of subjective cognitive assessments. Brief geriatric assessments have been administered by non-healthcare professionals. The duration taken to complete ranged from five to 20 min. Studies did not report significant change in the clinical outcomes of older adults except for better identification of those with higher needs.
Conclusion: The studies reported that brief geriatric assessments could identify older adults with unmet needs or geriatric syndromes, but they did not report improved health outcomes when combined with clinical intervention pathways. Clarity of brief geriatric assessments' questions is important to ensure the feasibility of using self-administered questionnaire by older adults. Future studies should determine which groups of older adults benefit the most from the brief assessments when these are paired with additional evaluations and interventions.
{"title":"Application and implementation of brief geriatric assessment in primary care and community settings: a scoping review.","authors":"Lay Khoon Lau, Penny Lun, Jonathan Gao, Edward Tan, Yew Yoong Ding","doi":"10.1186/s12877-024-05615-9","DOIUrl":"10.1186/s12877-024-05615-9","url":null,"abstract":"<p><strong>Background: </strong>Comprehensive Geriatric Assessment is the gold standard of clinical care for older patients but its application in the primary care setting is limited, possibly due to its time-consuming process. Hence, a brief geriatric assessment could be a feasible alternative. We conducted a scoping review to identify which brief geriatric assessment tools have been evaluated or implemented in primary and community care settings and to identify the domains assessed including their reported outcomes.</p><p><strong>Methods: </strong>CENTRAL, PubMed and Embase were searched using specific text words and MeSH for articles published from inception that studied evaluation or implementation of brief geriatric assessments in primary care or community setting.</p><p><strong>Results: </strong>Twenty-five articles were included in the review, of which 11 described brief geriatric assessments implemented in community, nine in primary care and five in mixed settings. Physical health, functional, mobility/balance and psychological/mental emerged as four domains that are most assessed in brief geriatric assessments. Self-reported questionnaire is the key approach, but uncertainty remains on the validity of subjective cognitive assessments. Brief geriatric assessments have been administered by non-healthcare professionals. The duration taken to complete ranged from five to 20 min. Studies did not report significant change in the clinical outcomes of older adults except for better identification of those with higher needs.</p><p><strong>Conclusion: </strong>The studies reported that brief geriatric assessments could identify older adults with unmet needs or geriatric syndromes, but they did not report improved health outcomes when combined with clinical intervention pathways. Clarity of brief geriatric assessments' questions is important to ensure the feasibility of using self-administered questionnaire by older adults. Future studies should determine which groups of older adults benefit the most from the brief assessments when these are paired with additional evaluations and interventions.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"2"},"PeriodicalIF":3.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11697857/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-01-02DOI: 10.1186/s12877-024-05591-0
Naaheed Mukadam, Louise Marston, Katie Flanagan, Etuini Ma'u, Gary Cheung, Dankmar Böhning
Background: To our knowledge capture-recapture techniques have not been used to estimate dementia prevalence using routinely collected data in England, nor have they been used to estimate changes in undiagnosed dementia over time. In this study we aimed to use routinely collected electronic health records to estimate the number of undiagnosed dementia cases there are in England and how this has changed over time. We also aimed to assess whether proportion of undiagnosed cases differed by age group, ethnicity, socioeconomic deprivation and sex.
Methods: We used routinely collected primary care data linked to hospital episode statistics from 1997 to 2018. We tabulated capture of dementia in each of the two datasets and used the Lincoln-Petersen estimator to estimate numbers of missing dementia diagnoses per year along with the estimated total number of cases and the proportion of cases identified. We calculated age and sex-adjusted prevalence of dementia for each year and used proportion of cases identified to estimate the underlying population prevalence of dementia per year. We conducted beta regression to estimate how sex, age band, deprivation and ethnic group affects the proportion of dementia cases identified, adjusting for year.
Results: Proportion of cases out of the estimated total that were identified, rose from 42.4% in 1997 to 84.4% in 2018. Estimated population prevalence of dementia rose from 1997 to a high of 4.4% in 2018 in those aged ≥ 65. Proportion of dementia cases identified did not vary by sex but a lower proportion of those from the South Asian ethnic group were diagnosed compared to the White population (coeff -0.115, 95% CI -0.218 to -0.011). Compared to those aged 65-74, those aged 75-84 and 85 + had higher proportions of dementia diagnosed (75-84 Coeff 0.259, 95% CI 0.153-0.366; 85 + Coeff 0.185, 95% CI 0.079-0.291). Those living in the two most deprived areas had a higher proportion of dementia diagnosed compared to the least deprived area (IMD quintile 4 vs 1 coeff 0.093, 95% CI 0.014 to 0.173, IMD quintile 5 vs 1 coeff 0.162, 95% CI 0.083 to 0.242).
Conclusions: Proportion of dementia cases identified has increased over time and results indicate that underlying prevalence of dementia may be lower than previously estimated but this needs replication. Greater focus needs to be given to those with dementia onset at younger ages and those from South Asian backgrounds as dementia is relatively under-diagnosed in these groups.
背景:据我们所知,在英国,捕获-再捕获技术尚未用于使用常规收集的数据来估计痴呆的患病率,也未用于估计未确诊痴呆的变化。在这项研究中,我们的目的是使用常规收集的电子健康记录来估计英国未确诊痴呆病例的数量,以及这一数字如何随着时间的推移而变化。我们还旨在评估未确诊病例的比例是否因年龄组、种族、社会经济剥夺和性别而异。方法:我们使用了1997年至2018年常规收集的与医院事件统计相关的初级保健数据。我们将两个数据集中痴呆的捕获情况制作成表格,并使用Lincoln-Petersen估计器来估计每年失智症诊断的数量,以及估计的病例总数和确定的病例比例。我们计算了每年经年龄和性别调整的痴呆症患病率,并使用确定的病例比例来估计每年潜在的痴呆症人群患病率。我们进行了贝塔回归,以估计性别、年龄、剥夺和种族群体如何影响识别出的痴呆病例比例,并对年份进行了调整。结果:确诊病例占估计总数的比例从1997年的42.4%上升到2018年的84.4%。在年龄≥65岁的人群中,痴呆症的估计人口患病率从1997年上升到2018年的4.4%。确诊痴呆病例的比例不因性别而异,但南亚族裔人群的确诊比例低于白人人群(coeff -0.115, 95% CI -0.218至-0.011)。与65-74岁的人相比,75-84岁和85岁以上的人被诊断为痴呆的比例更高(75-84 Coeff 0.259, 95% CI 0.153-0.366;85 + Coeff 0.185, 95% CI 0.079-0.291)。与生活在最贫困地区的人相比,生活在两个最贫困地区的人被诊断为痴呆症的比例更高(IMD五分位数4对1的系数0.093,95% CI 0.014至0.173,IMD五分位数5对1的系数0.162,95% CI 0.083至0.242)。结论:发现的痴呆病例比例随着时间的推移而增加,结果表明痴呆的潜在患病率可能低于先前的估计,但这需要重复。需要更加关注年龄较小的痴呆症患者和来自南亚背景的患者,因为这些人群的痴呆症诊断相对不足。
{"title":"Estimating undiagnosed dementia in England using capture recapture techniques.","authors":"Naaheed Mukadam, Louise Marston, Katie Flanagan, Etuini Ma'u, Gary Cheung, Dankmar Böhning","doi":"10.1186/s12877-024-05591-0","DOIUrl":"10.1186/s12877-024-05591-0","url":null,"abstract":"<p><strong>Background: </strong>To our knowledge capture-recapture techniques have not been used to estimate dementia prevalence using routinely collected data in England, nor have they been used to estimate changes in undiagnosed dementia over time. In this study we aimed to use routinely collected electronic health records to estimate the number of undiagnosed dementia cases there are in England and how this has changed over time. We also aimed to assess whether proportion of undiagnosed cases differed by age group, ethnicity, socioeconomic deprivation and sex.</p><p><strong>Methods: </strong>We used routinely collected primary care data linked to hospital episode statistics from 1997 to 2018. We tabulated capture of dementia in each of the two datasets and used the Lincoln-Petersen estimator to estimate numbers of missing dementia diagnoses per year along with the estimated total number of cases and the proportion of cases identified. We calculated age and sex-adjusted prevalence of dementia for each year and used proportion of cases identified to estimate the underlying population prevalence of dementia per year. We conducted beta regression to estimate how sex, age band, deprivation and ethnic group affects the proportion of dementia cases identified, adjusting for year.</p><p><strong>Results: </strong>Proportion of cases out of the estimated total that were identified, rose from 42.4% in 1997 to 84.4% in 2018. Estimated population prevalence of dementia rose from 1997 to a high of 4.4% in 2018 in those aged ≥ 65. Proportion of dementia cases identified did not vary by sex but a lower proportion of those from the South Asian ethnic group were diagnosed compared to the White population (coeff -0.115, 95% CI -0.218 to -0.011). Compared to those aged 65-74, those aged 75-84 and 85 + had higher proportions of dementia diagnosed (75-84 Coeff 0.259, 95% CI 0.153-0.366; 85 + Coeff 0.185, 95% CI 0.079-0.291). Those living in the two most deprived areas had a higher proportion of dementia diagnosed compared to the least deprived area (IMD quintile 4 vs 1 coeff 0.093, 95% CI 0.014 to 0.173, IMD quintile 5 vs 1 coeff 0.162, 95% CI 0.083 to 0.242).</p><p><strong>Conclusions: </strong>Proportion of dementia cases identified has increased over time and results indicate that underlying prevalence of dementia may be lower than previously estimated but this needs replication. Greater focus needs to be given to those with dementia onset at younger ages and those from South Asian backgrounds as dementia is relatively under-diagnosed in these groups.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"25 1","pages":"1"},"PeriodicalIF":3.4,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11694474/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142920534","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Calf muscular vein thrombosis (CMVT) is a type of distal deep vein thrombosis, which is common in geriatric hip fracture patients. However, studies focusing on whether the orthopedic operation has an impact on the prognosis of geriatric hip fracture patients with CMVT are very limited. Therefore, the aim of this study was to explore whether geriatric hip fractures with CMVT affect the mortality of patients within one year postoperatively. The difficulty of the operation, postoperative complications, the status of thrombosis, and function scores were also compared.
Materials and methods: Geriatric hip fracture patients who underwent surgery between January 2019 and January 2021 were included. Patients were divided into groups with and without CMVT by preoperative color Doppler ultrasound examination. Propensity score-matching (PSM) was performed in a ratio of 1:1 between the patient with and without CMVT groups. Baseline characteristics, laboratory results, perioperative indicators and prognosis of patients were collected retrospectively. Intraoperative and postoperative comparisons were conducted between patients with and without CMVT.
Results: Two hundred and sixty geriatric hip fracture patients were included. Eighty-nine patients in each group were matched after PSM. There was no significant difference in mortality between the two groups at one-month, three-month, six-month, and one-year postoperatively. However, patients with CMVT had longer hospital stays, a higher incidence of postoperative complications, and a higher incidence of thrombosis progression than patients without CMVT in the follow-up.
Conclusion: No significant difference in mortality within one year postoperatively was observed in Chinese geriatric hip fracture patients with or without CMVT formation. Strategies such as close monitoring the status of thrombosis, individualized care, and strengthening rehabilitation are recommended to reduce the risk of complications and optimize patient outcomes in this patient population.
Trial registration: Chinese Clinical Trial Registry (ChiCTR2300069411). Registered March 15, 2023, https://www.chictr.org.cn/showproj.html?proj=192079 .
{"title":"The effect of calf muscular vein thrombosis on the prognosis within one year postoperatively of geriatric hip fracture patients: a propensity score-matched analysis.","authors":"Jiabao Jiang, Fei Xing, Rong Luo, Zhao Chen, Hao Liu, Zhou Xiang, Xin Duan","doi":"10.1186/s12877-024-05601-1","DOIUrl":"10.1186/s12877-024-05601-1","url":null,"abstract":"<p><strong>Introduction: </strong>Calf muscular vein thrombosis (CMVT) is a type of distal deep vein thrombosis, which is common in geriatric hip fracture patients. However, studies focusing on whether the orthopedic operation has an impact on the prognosis of geriatric hip fracture patients with CMVT are very limited. Therefore, the aim of this study was to explore whether geriatric hip fractures with CMVT affect the mortality of patients within one year postoperatively. The difficulty of the operation, postoperative complications, the status of thrombosis, and function scores were also compared.</p><p><strong>Materials and methods: </strong>Geriatric hip fracture patients who underwent surgery between January 2019 and January 2021 were included. Patients were divided into groups with and without CMVT by preoperative color Doppler ultrasound examination. Propensity score-matching (PSM) was performed in a ratio of 1:1 between the patient with and without CMVT groups. Baseline characteristics, laboratory results, perioperative indicators and prognosis of patients were collected retrospectively. Intraoperative and postoperative comparisons were conducted between patients with and without CMVT.</p><p><strong>Results: </strong>Two hundred and sixty geriatric hip fracture patients were included. Eighty-nine patients in each group were matched after PSM. There was no significant difference in mortality between the two groups at one-month, three-month, six-month, and one-year postoperatively. However, patients with CMVT had longer hospital stays, a higher incidence of postoperative complications, and a higher incidence of thrombosis progression than patients without CMVT in the follow-up.</p><p><strong>Conclusion: </strong>No significant difference in mortality within one year postoperatively was observed in Chinese geriatric hip fracture patients with or without CMVT formation. Strategies such as close monitoring the status of thrombosis, individualized care, and strengthening rehabilitation are recommended to reduce the risk of complications and optimize patient outcomes in this patient population.</p><p><strong>Trial registration: </strong>Chinese Clinical Trial Registry (ChiCTR2300069411). Registered March 15, 2023, https://www.chictr.org.cn/showproj.html?proj=192079 .</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1050"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686951/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-31DOI: 10.1186/s12877-024-05641-7
Doris Gebhard, Julia I Frank
Background: Everyday life in residential long-term care is widely portrayed as boring. However, empirical evidence on this topic remains limited, particularly for the vulnerable group of people living with dementia. A better understanding of everyday life and the associated experiences of boredom could facilitate the development of practical strategies to reduce boredom in this target group. The aim of this study is therefore to analyse everyday activities, daily routines and the frequency and types of boredom in people living with dementia in residential long-term care.
Data and methods: In five long-term care facilities, participants were observed for two days in 20-minute time slots (from 7 am to 7 pm) using the Maastricht Electronic Daily Live Observation Tool. Semi-structured interviews were conducted with people living with dementia about their daily routines and experiences of boredom. Qualitative content analysis based on Mayring was applied, using the five boredom types from Goetz et al. as deductive categories. Observational data was analysed descriptively and merged with qualitative data on daily routines. In all, 46 people living with dementia (average age: 84.65 ± 7.15 years, 89.13% female, average DSS: 6.50 ± 3.15) were observed at 2760 time points. Of these, 17 participants took part in the interviews.
Results: The residents spend 47.5% of their day doing nothing and follow a routine that is strongly determined by communal meals. 62.5% of participants are bored, with 18.5% describing boredom as a constant/prevalent condition in their everyday lives. All five types of boredom are reflected in the interviews, with apathetic boredom being the most common.
Conclusions: Although people living with dementia follow almost the same daily routine in residential long-term care, they experience everyday life very differently, ranging from no boredom, to feelings of pleasant relaxation when bored to strongly negative feelings such as hopelessness and frustration. These findings suggest that interventions to prevent or reduce boredom need to be personalised in order to effectively combat the highly individual nature of boredom. Person-centred dementia care provides a valuable intervention strategy to meet this requirement.
{"title":"Everyday life and boredom of people living with dementia in residential long-term care: a merged methods study.","authors":"Doris Gebhard, Julia I Frank","doi":"10.1186/s12877-024-05641-7","DOIUrl":"10.1186/s12877-024-05641-7","url":null,"abstract":"<p><strong>Background: </strong>Everyday life in residential long-term care is widely portrayed as boring. However, empirical evidence on this topic remains limited, particularly for the vulnerable group of people living with dementia. A better understanding of everyday life and the associated experiences of boredom could facilitate the development of practical strategies to reduce boredom in this target group. The aim of this study is therefore to analyse everyday activities, daily routines and the frequency and types of boredom in people living with dementia in residential long-term care.</p><p><strong>Data and methods: </strong>In five long-term care facilities, participants were observed for two days in 20-minute time slots (from 7 am to 7 pm) using the Maastricht Electronic Daily Live Observation Tool. Semi-structured interviews were conducted with people living with dementia about their daily routines and experiences of boredom. Qualitative content analysis based on Mayring was applied, using the five boredom types from Goetz et al. as deductive categories. Observational data was analysed descriptively and merged with qualitative data on daily routines. In all, 46 people living with dementia (average age: 84.65 ± 7.15 years, 89.13% female, average DSS: 6.50 ± 3.15) were observed at 2760 time points. Of these, 17 participants took part in the interviews.</p><p><strong>Results: </strong>The residents spend 47.5% of their day doing nothing and follow a routine that is strongly determined by communal meals. 62.5% of participants are bored, with 18.5% describing boredom as a constant/prevalent condition in their everyday lives. All five types of boredom are reflected in the interviews, with apathetic boredom being the most common.</p><p><strong>Conclusions: </strong>Although people living with dementia follow almost the same daily routine in residential long-term care, they experience everyday life very differently, ranging from no boredom, to feelings of pleasant relaxation when bored to strongly negative feelings such as hopelessness and frustration. These findings suggest that interventions to prevent or reduce boredom need to be personalised in order to effectively combat the highly individual nature of boredom. Person-centred dementia care provides a valuable intervention strategy to meet this requirement.</p><p><strong>Clinical trial number: </strong>Not applicable.</p>","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1049"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686914/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-12-31DOI: 10.1186/s12877-024-05643-5
Galip Can Uyar, Mustafa Kemal Kılıç
<p><p>BACKGROUND AND RATIONALE: Thyroid dysfunction in older adults often mimics the signs of aging, impacting metabolism and overall physiological balance. While age-related chronic conditions have been extensively studied, the relationship between thyroid function and frailty remains underexplored.</p><p><strong>Objective: </strong>This study aimed to evaluate the effects of thyroid dysfunction on frailty among individuals aged 65 years and older. Thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), and thyroid peroxidase antibody (anti-TPO) levels were analyzed. The study further examined the correlation between thyroid dysfunction, chronic diseases, sociodemographic factors, and optimal TSH levels in relation to frailty, using the Study of Osteoporotic Fractures (SOF), Edmonton Frail Scale (EFS), and FRAIL scales.</p><p><strong>Methods: </strong>This cross-sectional study included 220 older adults with either treated or untreated thyroid dysfunction. Comprehensive geriatric assessments were conducted, including detailed medical histories, sociodemographic data collection, and thyroid function tests. Frailty was assessed using the SOF, EFS, and FRAIL scales. Multivariate logistic regression analyses were performed to identify significant associations between thyroid parameters and frailty.</p><p><strong>Results: </strong>The median age of participants was 73 years, and 68.2% (n = 150) were women. Frailty prevalence was significantly higher in individuals with abnormal TSH levels (outside the 0.5-6 mIU/L range). Lower fT3 levels and the fT3/fT4 ratio were significantly associated with frailty, particularly as assessed by the SOF and EFS scales. In contrast, the FRAIL scale revealed a significant association between increased frailty and lower fT3 levels only. Subgroup analysis indicated that in individuals aged ≥ 80 years, a lower fT3/fT4 ratio was consistently associated with frailty across all frailty scales, whereas in those aged < 80 years, lower TSH levels showed a strong association with frailty as assessed by the FRAIL scale. These findings underscore age-specific variations in the relationship between thyroid function and frailty.</p><p><strong>Conclusion: </strong>This study highlights the significant impact of thyroid dysfunction on frailty in older adults. Lower fT3 levels and the fT3/fT4 ratio emerged as key indicators of increased frailty, particularly on the SOF and EFS scales. Subgroup analysis further emphasized the importance of age-specific assessments, with a lower fT3/fT4 ratio being a critical indicator of frailty in individuals aged ≥ 80 years, while lower TSH levels were significant in those aged < 80 years. Abnormal TSH levels were strongly associated with frailty on the SOF scale, suggesting the need to consider thyroid dysfunction as a modifiable risk factor. Additionally, factors such as age, sex, education, thyroid medication use, and comorbidities influenced frailty status. Incorpora
{"title":"Evaluation of the effects of thyroid functions on frailty in geriatric patients using the Edmonton, SOF and FRAIL Scales.","authors":"Galip Can Uyar, Mustafa Kemal Kılıç","doi":"10.1186/s12877-024-05643-5","DOIUrl":"10.1186/s12877-024-05643-5","url":null,"abstract":"<p><p>BACKGROUND AND RATIONALE: Thyroid dysfunction in older adults often mimics the signs of aging, impacting metabolism and overall physiological balance. While age-related chronic conditions have been extensively studied, the relationship between thyroid function and frailty remains underexplored.</p><p><strong>Objective: </strong>This study aimed to evaluate the effects of thyroid dysfunction on frailty among individuals aged 65 years and older. Thyroid-stimulating hormone (TSH), free triiodothyronine (fT3), free thyroxine (fT4), and thyroid peroxidase antibody (anti-TPO) levels were analyzed. The study further examined the correlation between thyroid dysfunction, chronic diseases, sociodemographic factors, and optimal TSH levels in relation to frailty, using the Study of Osteoporotic Fractures (SOF), Edmonton Frail Scale (EFS), and FRAIL scales.</p><p><strong>Methods: </strong>This cross-sectional study included 220 older adults with either treated or untreated thyroid dysfunction. Comprehensive geriatric assessments were conducted, including detailed medical histories, sociodemographic data collection, and thyroid function tests. Frailty was assessed using the SOF, EFS, and FRAIL scales. Multivariate logistic regression analyses were performed to identify significant associations between thyroid parameters and frailty.</p><p><strong>Results: </strong>The median age of participants was 73 years, and 68.2% (n = 150) were women. Frailty prevalence was significantly higher in individuals with abnormal TSH levels (outside the 0.5-6 mIU/L range). Lower fT3 levels and the fT3/fT4 ratio were significantly associated with frailty, particularly as assessed by the SOF and EFS scales. In contrast, the FRAIL scale revealed a significant association between increased frailty and lower fT3 levels only. Subgroup analysis indicated that in individuals aged ≥ 80 years, a lower fT3/fT4 ratio was consistently associated with frailty across all frailty scales, whereas in those aged < 80 years, lower TSH levels showed a strong association with frailty as assessed by the FRAIL scale. These findings underscore age-specific variations in the relationship between thyroid function and frailty.</p><p><strong>Conclusion: </strong>This study highlights the significant impact of thyroid dysfunction on frailty in older adults. Lower fT3 levels and the fT3/fT4 ratio emerged as key indicators of increased frailty, particularly on the SOF and EFS scales. Subgroup analysis further emphasized the importance of age-specific assessments, with a lower fT3/fT4 ratio being a critical indicator of frailty in individuals aged ≥ 80 years, while lower TSH levels were significant in those aged < 80 years. Abnormal TSH levels were strongly associated with frailty on the SOF scale, suggesting the need to consider thyroid dysfunction as a modifiable risk factor. Additionally, factors such as age, sex, education, thyroid medication use, and comorbidities influenced frailty status. Incorpora","PeriodicalId":9056,"journal":{"name":"BMC Geriatrics","volume":"24 1","pages":"1051"},"PeriodicalIF":3.4,"publicationDate":"2024-12-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11686849/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142906352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}