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Frail, Feeble, or Fit? The Oldest Old: What Should We Do Differently for the Geriatric Patient Undergoing Anesthesia—If Anything? 虚弱,虚弱,还是健康?最老的老人:如果有的话,我们应该为接受麻醉的老年病人做些什么?
Pub Date : 2013-01-01 DOI: 10.1097/ASA.0b013e31829aeb53
Sheila R. Barnett
Learning Objectives: As a result of completing this activity, the participant will be able to Discuss the definition and anesthetic implications of frailty Describe current demographic challenges and morbidity and mortality curves for the elderly Discuss the natural consequences of aging and the concept of reserve function Describe risk reduction strategies that can be applied to the oldest old Describe management strategies that could be used as quality indicators
学习目标:完成本活动后,参与者将能够讨论衰弱的定义和麻醉含义,描述当前的人口统计学挑战和老年人的发病率和死亡率曲线,讨论老龄化的自然后果和储备功能的概念,描述可应用于老年人的风险降低策略,描述可作为质量指标的管理策略
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引用次数: 0
Hypoxia During Thoracic Surgery: Practical Advice for the Anesthesiologist 胸外科手术中的缺氧:给麻醉师的实用建议
Pub Date : 2013-01-01 DOI: 10.1097/ASA.0B013E31829953FC
Javier H. Campos
Double-lumen tubes or bronchial blockers are used to provide one-lung ventilation (OLV) in patients undergoing lung, esophageal, thoracic vascular, minimally invasive cardiac, and occasionally mediastinal surgery. During OLV, an intrapulmonary shunt may result in hypoxemia related in part to collapse of the nondependent lung and increased atelectatic areas in the dependent lung. Hypoxemia by definition is a decrease in oxygen saturation (SpO2) to less than 90% 4 or an arterial oxygen tension (PaO2) of less than 60 mmHg when the patient is being ventilated at an inspired oxygen fraction (FiO2) of 1.0. 5 The incidence of hypoxemia during OLV has been reported to be 1 to 10%. This relative infrequency is related in part to advances with routine use of a fiberoptic bronchoscope for optimal placement of lung isolation devices. It is also attributable to the introduction of newer volatile anesthetics that cause less inhibition of hypoxic pulmonary vasoconstriction (HPV) in a dose-dependent manner and less venous admixture during OLV. This review focuses on the predictors of hypoxia during OLV, the pathophysiology of HPV, protective ventilation maneuvers to restore or improve arterial oxygenation, the effects of anesthetics on hypoxia and inflammation, and cerebral desaturation episodes and hypoxia during OLV.
双腔管或支气管阻滞剂用于肺、食管、胸血管、微创心脏和偶尔的纵隔手术的患者提供单肺通气(OLV)。在OLV期间,肺内分流可能导致低氧血症,部分原因与非依赖性肺塌陷和依赖性肺无电区增加有关。低氧血症的定义是当患者在吸入氧分数(FiO2)为1.0的情况下进行通气时,血氧饱和度(SpO2)降至90%以下4或动脉血氧压(PaO2)低于60 mmHg。据报道,OLV期间低氧血症的发生率为1%至10%。这种相对罕见的情况部分与常规使用纤维支气管镜进行肺隔离装置的最佳放置有关。这也是由于引入了较新的挥发性麻醉剂,以剂量依赖的方式减少了对缺氧肺血管收缩(HPV)的抑制,并且在OLV期间减少了静脉混合。本文综述了OLV期间缺氧的预测因素、HPV的病理生理、恢复或改善动脉氧合的保护性通气操作、麻醉剂对缺氧和炎症的影响、OLV期间脑去饱和发作和缺氧的影响。
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引用次数: 4
Risk Evaluation and Mitigation Strategies (REMS), Pill Mills, and Responsible Opioid Prescribing 风险评估和缓解策略(REMS),药丸厂和负责任的阿片类药物处方
Pub Date : 2013-01-01 DOI: 10.1097/ASA.0b013e31829a1f54
R. Miguel
Over the past 20 years, drug overdose deaths in the United States have tripled. More than 100 people die each day secondary to prescription drug use, whether related to drug abuse, misuse, or adverse events. In July 2012, the Drug Abuse Warning Network reported that of 4.8 million drug-related visits to US emergency departments in 2010, 46.8% were due to drug abuse or misuse. Prescription drugs had the highest representation of all abused drugs at a frequency of 435 per 100,000 population. Because Florida is the state with the greatest number of medications dispensed and the highest drug mortality, the actions of that state have a far-reaching impact because of the enormous volume of drugs diverted from Florida. Recognizing the problem, the US Food and Drug Administration (FDA) started Risk Evaluation and Mitigation Strategies (REMS) as a source of education. REMS require drug manufacturers to educate physicians who, in turn, will educate their patients about the proper use of high-risk medications, including opioids. This chapter addresses the problem of clinics that appear to operate as pain clinics but really exist to dispense prescriptions for medication, or ‘‘pill mills,’’ and their contribution to the national prescription drug epidemic. A template for responsible controlled substance prescribing, which includes complete history taking and physical examination with particular attention to comorbidities (including psychiatric disorders), is described. Finally, an overview of the available risk assessment and ongoing management tools is presented.
在过去的20年里,美国的药物过量死亡人数增加了两倍。每天有100多人死于处方药使用,无论是与药物滥用、误用还是不良事件有关。2012年7月,药物滥用预警网络(Drug Abuse Warning Network)报告称,2010年美国急诊科480万例与毒品有关的就诊中,46.8%是由于药物滥用或误用。处方药在所有滥用药物中所占比例最高,为每10万人435例。由于佛罗里达州是分发药物数量最多、药物死亡率最高的州,该州的行动具有深远的影响,因为从佛罗里达州转移的药物数量巨大。认识到这一问题,美国食品和药物管理局(FDA)启动了风险评估和缓解战略(REMS),作为教育的一个来源。REMS要求药品制造商教育医生,医生反过来教育患者正确使用高风险药物,包括阿片类药物。本章讨论了一些诊所的问题,这些诊所表面上是作为疼痛诊所运作的,但实际上是为了分发药物处方或“药丸工厂”,以及它们对全国处方药泛滥的贡献。描述了负责任的受控物质处方模板,其中包括完整的病史记录和体格检查,特别注意合并症(包括精神疾病)。最后,概述了可用的风险评估和正在进行的管理工具。
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引用次数: 0
Perioperative Acid–Base Disturbances: Evaluation and Management 围手术期酸碱干扰:评估与处理
Pub Date : 2012-01-01 DOI: 10.1097/ASA.0B013E31825F3C30
M. Keegan
As perioperative physicians, anesthesiologists regularly face dilemmas in patients who have gas exchange and acid–base abnormalities. Even in the absence of technical problems, some individuals are difficult to oxygenate and ventilate intraoperatively. Hypoxemia and hypercapnia commonly occur in the postanesthesia care unit and on the surgical wards. Intensive care unit patients with respiratory failure and metabolic derangements may require operative intervention and pose significant management problems. Furthermore, the effects on patient physiology of a variety of perioperative metabolic insults must be considered. Assessment of acid–base and metabolic derangements requires evaluation of blood gases, electrolytes, and other laboratory data. This chapter discusses acid–base physiology as it applies to the perioperative period, and provides an approach to the interpretation of arterial blood gases and electrolytes with a focus on acid–base disorders.
作为围手术期的医生,麻醉师经常面对有气体交换和酸碱异常的患者的困境。即使在没有技术问题的情况下,有些人在术中也难以充氧和通气。低氧血症和高碳酸血症常见于麻醉后护理病房和外科病房。重症监护病房的呼吸衰竭和代谢紊乱患者可能需要手术干预,并提出重大的管理问题。此外,必须考虑各种围手术期代谢损伤对患者生理的影响。评估酸碱和代谢紊乱需要评估血气、电解质和其他实验室数据。本章讨论了适用于围手术期的酸碱生理学,并提供了一种解释动脉血气和电解质的方法,重点是酸碱紊乱。
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引用次数: 1
Emergency Preparedness: Managing Victims of Chemical, Biological, Radiological, Nuclear, or High-explosive (CBRNE) Agents 应急准备:管理化学、生物、辐射、核或高爆(CBRNE)剂的受害者
Pub Date : 2012-01-01 DOI: 10.1097/ASA.0b013e3182622bab
M. Murray
Preparing to manage disasters originating from natural events, industrial accidents, or, of more interest recently, caused intentionally by terrorists using chemical, biological, radiological, nuclear, or highexplosive (CBRNE) agents is a high priority for the US government and military as well as the American Society of Anesthesiologists. Even though natural and man-made disasters have occurred for millennia, the use of CBRNE agents and devices by terrorists in recent decades has emphasized the need for increased preparedness. Natural disasters that occurred in 2011 killed tens of thousands of people and caused more than 350 billion dollars in losses. The earthquake and resulting tsunami in Japan, earthquakes in Haiti and New Zealand, the floods in Thailand and the Eastern United States (caused by Hurricane Irene), and the tornados that touched down in Joplin, Missouri, and in Alabama have produced calamities that were almost unimaginable in the past. In Alabama and Missouri, whole neighborhoods were wiped off the map. In addition to the direct damage caused by the earthquake and tsunami in Japan, the effect on the Fukushima nuclear power plant in Okuma continues to cause significant concern and morbidity. The intent of this chapter is to review and highlight what anesthesiologists need to know to manage victims when natural disasters occur or when CBRNE devices or agents, whether used by terrorists or released during an industrial accident, result in a major disaster causing a high number of casualties.
准备好应对自然事件、工业事故,或者最近更感兴趣的,由恐怖分子使用化学、生物、放射性、核或高爆剂(CBRNE)故意造成的灾难,是美国政府、军方以及美国麻醉医师协会的高度优先事项。尽管自然灾害和人为灾害已经发生了几千年,但近几十年来恐怖分子使用CBRNE制剂和装置的情况强调了加强防备的必要性。2011年发生的自然灾害造成数万人死亡,造成超过3500亿美元的损失。日本的地震及其引发的海啸,海地和新西兰的地震,泰国和美国东部的洪水(由飓风艾琳引起),以及在密苏里州乔普林和阿拉巴马州登陆的龙卷风,都造成了过去几乎无法想象的灾难。在阿拉巴马州和密苏里州,整个社区被从地图上抹去。除了日本地震和海啸造成的直接破坏外,对大隈岛福岛核电站的影响继续引起重大关注和发病率。本章的目的是回顾和强调当自然灾害发生时,或者当CBRNE设备或代理人(无论是恐怖分子使用的还是在工业事故中释放的)导致造成大量伤亡的重大灾难时,麻醉师需要知道什么来管理受害者。
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引用次数: 0
A Fire in the Operating Room: It Could Happen to You! 手术室失火:可能发生在你身上!
Pub Date : 2012-01-01 DOI: 10.1097/ASA.0b013e3182622c62
J. Ehrenwerth
Operating room (OR) fires are probably more common today than when anesthesiologists used explosive agents. This is the result of more combustible materials in the OR, more ignition sources, and the prevalent use of open oxygen during monitored anesthesia care. The Emergency Care Research Institute (ECRI) estimates that 500 to 600 OR fires occur each year in the United States. Most are self-limited and do not result in significant injury to the patient. However, there are many instances of a patient receiving a serious burn and occasionally death has been reported. As recently as 2009, a 65-year-old woman in southern Illinois died a few days after she was burned in an OR fire. Approximately 65% of fires today involve surgery on the head, neck, and upper chest area.
今天的手术室(OR)火灾可能比麻醉师使用炸药时更常见。这是由于在手术室中有更多的可燃物质,更多的火源,以及在麻醉监护期间普遍使用开放氧气。紧急护理研究所(ECRI)估计,美国每年发生500至600起手术室火灾。大多数是自限性的,不会对患者造成严重伤害。然而,也有许多病人严重烧伤,偶尔死亡的报告。就在2009年,伊利诺斯州南部一名65岁的妇女在手术室大火中被烧伤几天后死亡。如今,大约65%的火灾涉及头部、颈部和胸部上部的手术。
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引用次数: 3
Physics in Anesthesiology: Basic Science Review 麻醉学中的物理学:基础科学评论
Pub Date : 2012-01-01 DOI: 10.1097/ASA.0b013e31825da79e
K. Gipson, J. Gross
Safety in the delivery of anesthesia is inextricably linked to the proper functioning of anesthesia equipment and resuscitative equipment, and to the presence of a consultant in anesthesia who can maintain safety in the face of equipment failure. This consultant relies upon basic principles in troubleshooting and evaluation of alternatives when equipment malfunction occurs. This chapter reviews the standards and principles that underlie the function of anesthesia equipment, including measurement of patient variables and prevention of common safety mishaps (see Supplemental Digital Content 1, http://links.lww.com/ASA/A124).
麻醉输送的安全与麻醉设备和复苏设备的正常运行密不可分,也与麻醉咨询师在设备故障时能够保持安全密切相关。当设备发生故障时,该顾问依赖于故障排除和评估替代方案的基本原则。本章回顾了麻醉设备功能基础的标准和原则,包括患者变量的测量和常见安全事故的预防(参见补充数字内容1,http://links.lww.com/ASA/A124)。
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引用次数: 0
Hematological Issues in Cardiovascular Surgery Patients 心血管手术患者血液学问题
Pub Date : 2012-01-01 DOI: 10.1097/ASA.0b013e31825e9a9e
L. Shore-lesserson, L. Enriquez
Learning Objectives: As a result of completing this activity, the participant will be able to Explain heparin resistance and alternatives to overcome it Describe heparin-induced thrombocytopenia and employ alternatives to heparin in the cardiac patient Compare and contrast the various direct thrombin inhibitors Understand the utilization of antifibrinolytic therapy in cardiac surgery Describe the various antiplatelet medications and use of point-of-care testing to guide therapy Describe the use of recombinant activated factor VII as rescue therapy in the bleeding cardiac patient
学习目标:完成这项活动的结果是,参与者将能够解释肝素耐药和克服肝素耐药的替代方案描述肝素诱发的血小板减少症,并在心脏病患者中采用肝素的替代方案比较和对比各种直接凝血酶抑制剂了解心脏手术中抗纤溶治疗的使用描述各种抗血小板药物和使用即时检测来指导治疗描述重组活化因子VII作为抢救治疗的使用心脏出血病人
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引用次数: 1
A Child With a Difficult Airway: What Do I Do Next? 一个呼吸道困难的孩子:接下来我该怎么做?
Pub Date : 2012-01-01 DOI: 10.1097/ASA.0b013e31825e9958
S. Wald
The challenge inherent to the care of infants and children is the basic principle that their development is a dynamic process. This is an important consideration when caring for a pediatric patient with a difficult airway. This is compounded by the fact that growth and change has extra metabolic demands such that the smaller the patient, the higher their relative metabolism. This increases oxygen consumption and in the cases of respiratory compromise hastens the effects of apnea. It is for these reasons that the difficult pediatric airway is particularly demanding of special attention.
照顾婴儿和儿童所固有的挑战是他们的发展是一个动态过程这一基本原则。这是一个重要的考虑,当照顾儿童病人有困难的气道。由于生长和变化需要额外的代谢,所以病人越小,他们的相对代谢就越高。这增加了氧气的消耗,在呼吸系统受损的情况下,加速了呼吸暂停的影响。正是由于这些原因,困难的儿科气道特别需要特别注意。
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引用次数: 11
Anesthesia in Satellite Locations 卫星位置麻醉
Pub Date : 2012-01-01 DOI: 10.1097/ASA.0b013e31826304c3
B. Gentz
Introduction The provision of anesthesia outside the operating room provides a unique set of challenges. The standards and principles that underlie the care of the patient should not be abandoned in satellite locations. However, patients who are referred for procedures in satellite locations may present with minimal preoperative information, possess challenging physical and anesthetic histories, and be scheduled in such a manner as to limit preparation time. The layout and special requirements of the satellite location can create unexpected barriers and may limit access to the patient and the availability of the anesthesia equipment. The challenges for the anesthesiologists include an unfamiliar environment, inadequate anesthesia support and insufficient number of trained personnel, and cramped, dark quarters and variability of monitoring modalities. In radiation oncology, MRI and occasionally the GI suite problems with noise and suboptimal positioning of the patient may be an issue.
手术室外麻醉的提供带来了一系列独特的挑战。在卫星地点不应放弃作为病人护理基础的标准和原则。然而,在卫星位置转介手术的患者可能只有很少的术前信息,具有挑战性的身体和麻醉史,并且以限制准备时间的方式安排。卫星位置的布局和特殊要求可能会产生意想不到的障碍,并可能限制接近患者和麻醉设备的可用性。麻醉师面临的挑战包括不熟悉的环境、麻醉支持不足、训练有素的人员数量不足、狭窄、黑暗的病房和监测方式的可变性。在放射肿瘤学、MRI和偶尔的GI套件中,噪声问题和患者的次优定位可能是一个问题。
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引用次数: 2
期刊
Refresher courses in anesthesiology
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