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The Pulmonary Artery Catheter in 2014: Past, Present, and Is There a Future? 2014年的肺动脉导管:过去、现在和未来?
Pub Date : 2014-01-01 DOI: 10.1097/ASA.0000000000000013
R. Fink, J. Mark
Learning Objectives: As a result of completing this activity, the participant will be able to Explain the evidence base (or lack thereof) for pulmonary artery catheter use Discuss complications and risks associated with pulmonary artery catheters Describe the various waveform components on central venous pressure and pulmonary artery catheter tracings and describe their physiological basis Measure intracardiac pressure and understand how the interpretation of waveforms and pressures may assist with diagnostic and therapeutic decisions
学习目标:完成这项活动的结果是,参与者将能够解释使用肺动脉导管的证据基础(或缺乏证据基础)讨论与肺动脉导管相关的并发症和风险描述中心静脉压和肺动脉导管示踪的各种波形成分并描述其生理基础测量心内压并理解波形和压力的解释如何有助于诊断和治疗决策
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引用次数: 0
Anesthetic Implications of Pharmacogenetics 药物遗传学的麻醉意义
Pub Date : 2014-01-01 DOI: 10.1097/ASA.0000000000000010
I. Bentov
In a recent editorial in Anesthesiology 1 the authors stated that ‘‘education in genomics will be essential for practitioners to translate genomic discoveries into clinical practice.’’ The Refresher Course lecture on which this chapter is based was designed to be part of that effort. First, basic concepts and nomenclature of genetics are reviewed. We will then discuss examples of the influence of genetic information and genetic research strategies upon patient care in anesthesia. Envision that you are reviewing the laboratory results for your next patient and you find that the blood counts and serum chemistries are all within normal limits. However, you notice that your patient has had genetic testing and is carrying the allele A290G (*1b) for the gene CYP3A4, homozygous for butyrylcholinesterase Asp70Gly polymorphism, and has an alarming single nucleotide polymorphism (SNP) analysis of natriuretic peptide receptor C/guanylate cyclase C (atrionatriuretic peptide receptor C), also known as NPR3, and natriuretic peptide precursor A (NPPA) and B (NPPB) genes (Supplemental Digital Content 1, http://links.lww.com/ASA/ A459). As she comes into your office, you see that she has flaming red hair. During the interview she claims that she requires large doses of local anesthetics when she visits the dentist. Would this information alter your anesthetic plan?
在《麻醉学》杂志最近的一篇社论中,作者指出:“基因组学教育对于从业者将基因组学发现转化为临床实践至关重要。本章所依据的复习课程讲座就是这一努力的一部分。首先,综述了遗传学的基本概念和术语。然后,我们将讨论遗传信息和遗传研究策略对麻醉患者护理的影响的例子。设想一下,你正在为你的下一个病人检查化验结果,你发现血液计数和血清化学成分都在正常范围内。然而,您注意到您的患者进行了基因检测,携带基因CYP3A4的等位基因A290G (*1b),丁基胆碱酯酶Asp70Gly多态性纯合子,并且钠肽受体C/鸟苷酸环化酶C(心房钠肽受体C)(也称为NPR3)和钠肽前体A (NPPA)和B (NPPB)基因的单核苷酸多态性(SNP)分析令人担忧(补充数字内容1,http://links.lww.com/ASA/ A459)。当她走进你的办公室时,你看到她有一头火红的头发。在采访中,她声称自己去看牙医时需要大剂量的局部麻醉剂。这个信息会改变你的麻醉计划吗?
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引用次数: 2
Mindfulness and Anesthesiology 正念和麻醉学
Pub Date : 2014-01-01 DOI: 10.1097/ASA.0000000000000014
R. Holzman
Learning Objectives: As a result of completing this activity, the participant will be able to Incorporate principles of mindfulness into a portfolio of vigilance, clinical decision making, and error reduction in the practice of anesthesiology Apply enhanced mindfulness techniques in the context of clinical anesthesiology practice Contrast mindfulness challenges and opportunities in the setting of multitasked dynamic perioperative care Recognize that mindfulness learned well in one area is an available competency that diffuses to other areas and transfers from professional to personal life
学习目标:作为完成这个活动的结果,参与者将能够将正念的原则融入到警觉、临床决策、在临床麻醉学实践中应用增强的正念技术在多任务动态围手术期护理环境中对比正念的挑战和机遇认识到,在一个领域学好正念是一种可用的能力,可以扩散到其他领域,并从专业转移到个人生活
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引用次数: 0
Preoperative Identification, Evaluation, and Optimization of the Highest Risk Patients 高危患者的术前识别、评估和优化
Pub Date : 2014-01-01 DOI: 10.1097/ASA.0000000000000017
B. Sweitzer
Learning Objectives: As a result of completing this activity, the participant will be able to Describe medical conditions that predict patients at risk for a poor outcome Evaluate screening tools and algorithms to identify and manage high-risk patients preoperatively Implement key preoperative practices to improve outcomes for patients in American Society of Anesthesiologists Physical Status 3 or 4
学习目标:作为完成本活动的结果,参与者将能够描述预测有不良预后风险的患者的医疗状况评估筛查工具和算法,以识别和管理术前高危患者实施关键的术前实践,以改善美国麻醉医师协会物理状态3或4中的患者的预后
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引用次数: 0
Perioperative Stroke 围手术期中风
Pub Date : 2014-01-01 DOI: 10.1097/ASA.0000000000000015
L. Moore, A. Gelb
Learning Objectives: As a result of completing this activity, the participant will be able to Describe patient comorbidities and surgical procedures that may place surgical patients at particular risk for perioperative stroke Recognize perioperative events that may be associated with stroke Explain initial management steps and potential interventions for postoperative patients with evidence of acute ischemic stroke
学习目标:作为完成本活动的结果,参与者将能够描述可能使手术患者处于围手术期卒中特别风险的患者合并症和外科手术,识别可能与卒中相关的围手术期事件,解释有急性缺血性卒中证据的术后患者的初始管理步骤和潜在干预措施
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引用次数: 0
The Expert Pathway: What You Can Do to Improve Your Performance 专家途径:你能做些什么来提高你的表现
Pub Date : 2013-01-01 DOI: 10.1097/ASA.0b013e318299f9a3
K. Baker
The Expert Pathway is an approach to professional development aimed at improving teaching, learning and performance in the domain of medicine. The approach is derived from the study of actual experts from a variety of different domains. Results from cognitive science are also applied as they relate to performance improvement. The ultimate goal is not simply to become competent (i.e. sufficient or adequate but not exceptional) rather the goal of the expert pathway is to reach towards expert performance. Performance in the domain of medicine has a great many contributing factors. These include motivation, environment, native ability or talent, employed strategies, self-regulation, costs and goal orientation. The expert pathway focuses on aspects of performance that are under an individual’s control such as employing selected strategies and persisting in the face of a setback.
专家途径是一种专业发展的方法,旨在改善医学领域的教学、学习和表现。该方法来源于来自不同领域的实际专家的研究。认知科学的研究结果也适用于表现改善。最终目标不是简单地变得有能力(即足够或足够,但不例外),而是专家途径的目标是达到专家的表现。医学领域的表现有很多影响因素。这些因素包括动机、环境、天生能力或天赋、雇佣策略、自我调节、成本和目标导向。专家路径侧重于个人控制的绩效方面,如采用选定的策略和面对挫折时的坚持。
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引用次数: 0
Safety and Human Factors in the Operating Room 手术室的安全与人为因素
Pub Date : 2013-01-01 DOI: 10.1097/ASA.0b013e31829aea76
K. Ruskin
E ffective decision-making, risk management, and teamwork are essential components of patient safety. Anesthesiologists work as part of a multidisciplinary team in a complex, stressful environment that has multiple distractions and is intolerant of errors. Frequent interaction is required with sophisticated medical equipment and personnel who have varying backgrounds and levels of education. As part of an ongoing effort to improve patient safety, numerous techniques have been adopted from the aviation industry in order to decrease the frequency and severity of critical events caused by human error. Anesthesiologists were among the first to adopt human factors, industrial engineering, and operations research as part of clinical practice, but other specialties soon followed. A recent editorial highlighted the growing body of articles on human factors in the medical literature—more than 140 papers on crisis resource management— demonstrating the growing level of interest in this topic. Research in the fields of safety and human factors continues to evolve, and current interests include the early detection of error-producing situations and the design of error-resistant systems. Using these well-developed tools for risk assessment, judgment, and decision-making may help to make the operating room a safer place.
有效的决策、风险管理和团队合作是患者安全的重要组成部分。麻醉师作为一个多学科团队的一部分,在一个复杂、紧张的环境中工作,有多种干扰,不能容忍错误。需要经常与复杂的医疗设备和具有不同背景和教育水平的人员互动。作为提高患者安全的持续努力的一部分,航空业采用了许多技术,以减少由人为错误引起的关键事件的频率和严重程度。麻醉师是最早将人为因素、工业工程和运筹学作为临床实践的一部分的人之一,但其他专业也很快跟进。最近的一篇社论强调指出,医学文献中关于人为因素的文章越来越多——140多篇关于危机资源管理的论文——表明人们对这一主题的兴趣日益浓厚。安全和人为因素领域的研究不断发展,目前的兴趣包括早期发现产生错误的情况和设计抗错误系统。使用这些完善的工具进行风险评估、判断和决策,可能有助于使手术室成为一个更安全的地方。
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引用次数: 1
Patient Blood Management From Blood Product to Patient-centered Care 患者血液管理:从血液制品到以患者为中心的护理
Pub Date : 2013-01-01 DOI: 10.1097/ASA.0b013e318299fb18
A. Shander
Evidence has shown that the clinical practice of liberal use of allogeneic blood transfusion is in dire need of reassessment. Concerns regarding the safety and efficacy of allogeneic blood transfusions, their impact on patient outcomes, and the astounding costs and challenges associated with supply reserves of blood products have fueled the quest for alternative strategies to reduce blood use while meeting the needs of a growing (and increasingly aging) population (Supplemental Digital Content 1, http:// links.lww.com/ASA/A333). Blood has always been perceived as a ‘‘life saver’’ and, as such, is an emotional topic. The revisiting of transfusion practices has highlighted the potential risks associated with allogeneic blood (Table 1) and offers a lack of convincing evidence of its benefit in nonhemorrhaging and many transfusion-dependent patients. The evidence highlighting the association of allogeneic blood transfusion with worse outcomes—not just the known and relatively rare side effects of transfusion, but significant and substantial negative impact on mortality, morbidity, and length of hospital stay—is rapidly growing.
有证据表明,自由使用同种异体输血的临床实践迫切需要重新评估。对同种异体输血的安全性和有效性、对患者预后的影响以及与血液制品供应储备相关的惊人成本和挑战的担忧,促使人们寻求替代策略,以减少血液使用,同时满足日益增长(和日益老龄化)的人口需求(补充数字内容1,http:// links.lww.com/ASA/A333)。血液一直被认为是“生命的救星”,因此,它是一个感性的话题。输血实践的重新审视强调了与异体血液相关的潜在风险(表1),并提供了缺乏令人信服的证据证明其对非出血和许多输血依赖患者的益处。越来越多的证据表明,异基因输血会带来更糟糕的结果——不仅是已知的和相对罕见的输血副作用,而且对死亡率、发病率和住院时间也有显著的负面影响。
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引用次数: 0
State-of-the-Art Labor Analgesia 最先进的分娩镇痛
Pub Date : 2013-01-01 DOI: 10.1097/ASA.0b013e31829a1e34
K. Nelson
Patient-controlled Epidural Analgesia and Programmed Intermittent Epidural Bolusing Once a catheter has been placed into the epidural space, several options are available to maintain analgesia (Supplemental Digital Content 1, http://links.lww.com/ ASA/A347). One of the first methods to be used was intermittent bolusing on patient request. Once the effect of the initial dose of local anesthetic would begin to subside, contraction pain would return and the patient would request more medication, at which time the anesthesiologist would provide analgesia using another bolus dose of local anesthetic. The obvious disadvantage to this technique is the relatively large amount of manpower required. Other disadvantages include noncontinuous pain relief and an intermittent increase in side effects such as hypotension and motor blockade. The natural progression in management of labor analgesia was, then, to use infusions to maintain analgesia; however, early infusion pumps were relatively primitive and sometimes unreliable, and data were lacking to guide infusion rates. A large body of research was eventually published to help rectify the problem, and it was during this time that the next step in the evolution of maintenance of labor analgesia occurred: patient-controlled epidural analgesia (PCEA). By this time, copious experience had accumulated with the use of intravenous patient-controlled analgesia, and the same principles were then applied to PCEA. However, it was soon discovered that there are some important differences between opioid-based intravenous patient-controlled analgesia for acute postoperative pain and local anesthetic–based PCEA for labor analgesia. Perhaps most important, a basal infusion was found to be very effective
患者控制的硬膜外镇痛和程序性间歇硬膜外灌注一旦将导管置入硬膜外间隙,有几种选择可用于维持镇痛(补充数字内容1,http://links.lww.com/ ASA/A347)。最早使用的方法之一是应患者要求间歇性服用。一旦初始剂量的局麻药的效果开始减弱,收缩性疼痛又会出现,病人会要求更多的药物治疗,这时麻醉师会使用另一剂量的局麻药提供镇痛。这种技术的明显缺点是需要相对大量的人力。其他缺点包括非持续性疼痛缓解和间歇性增加的副作用,如低血压和运动阻滞。因此,分娩镇痛管理的自然进展是使用输液来维持镇痛;然而,早期的输液泵相对原始,有时不可靠,缺乏数据来指导输液速率。大量的研究最终被发表,以帮助纠正这个问题,也就是在这个时候,发生了维持分娩镇痛进化的下一步:患者控制硬膜外镇痛(PCEA)。此时,静脉自控镇痛的使用已经积累了丰富的经验,同样的原则也被应用于PCEA。然而,人们很快发现,以阿片类药物为基础的术后急性疼痛静脉自控镇痛与以局麻为基础的PCEA分娩镇痛存在一些重要差异。也许最重要的是,基础输注被发现非常有效
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引用次数: 0
Pulmonary Hypertension and Management of Perioperative Right Ventricular Failure 肺动脉高压与围手术期右心衰的处理
Pub Date : 2013-01-01 DOI: 10.1097/ASA.0b013e3182995629
Johann Strumpher, E. Jacobsohn
Learning Objectives: As a result of completing this activity, the participant will be able to Discuss pulmonary hypertension (PH) as a disease entity including its definition, pathogenesis, classification, diagnosis, and treatment options Describe the pathophysiology of acute perioperative right ventricular (RV) failure in patients with PH Explain the principles of treatment for acute perioperative RV failure
学习目标:完成本活动后,参与者将能够讨论肺动脉高压(PH)作为一种疾病实体,包括其定义、发病机制、分类、诊断和治疗方案。描述肺动脉高压患者急性围手术期右心室衰竭的病理生理学。解释急性右心室衰竭的治疗原则
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引用次数: 1
期刊
Refresher courses in anesthesiology
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