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A Meta-Analysis Taxonomizing Empathy in Schizophrenia 精神分裂症共情分类的元分析
Pub Date : 2019-05-06 DOI: 10.24966/pda-0150/100016
Sumayyah Varachhia
A Meta-Analysis Tax- onomizing Empathy in Schizophrenia. J mental health the general on measures purported assess Commonly, studies have used the Interpersonal a self-report questionnaire using four sub-scales: Fantasy, perspective-taking, personal Abstract Background Trait empathy is integral to relationship development and main- tenance. Therefore, impairment in this ability can have an adverse effect on many domains of life including social, sexual, and marital. Previous reviews show in schizophrenia, this ability to be impaired but with a high amount of heterogeneity that is yet to be explored more thoroughly. Considering this, we aim to synthesise the extent literature using a meta-analytic approach and examine the source of the heterogeneity observed in previous reviews and develop taxonomy of empa- thy deficits in schizophrenia. Hedges’ g was calculated for cognitive and affective empathy using random effects models. Meta-regres- sion models of key cognitive, clinical and demographic risk and protective factors were run. These included: Impact year of publication, age, gender, ethnicity, education, general IQ, verbal/pre-morbid IQ, global neuro-cognition, positive, negative and general symptoms of schizophrenia, age at schizophrenia diagnosis, duration of illness and medication has on cognitive and affective empathy. A literature search revealed 39 independent studies examining em- pathy in schizophrenia. Healthy controls scored higher than people with a diagnosis of schizophrenia, with a small effect size for affective empathy (Hedges’ g = 0.29) and a medium effect size for cognitive empathy (Hedges’ g = 0.53). Both components were heterogeneous. Analyses using meta-regression models found age at diagnosis and the duration of illness moderated the difference in effect size for cog- nitive empathy, such that those with an earlier diagnosis or a more chronic course exhibit greater difficulty in cognitive empathy com - pared to healthy controls. We find a longer duration of illness and younger age at clinical diagnosis enhances impairments in cognitive empathy in severe and enduring schizophrenia. For affective empathy, we conclude, com- pared to healthy controls, some patients report having a deficit [i.e. experience lower affective empathy], others report comparable lev- els, and the remaining report to be experiencing higher emotional arousal. As an earlier diagnosis, prolonged illness course and dys- functional emotional reactions are significant risk factors of poorer empathic interactions, it will be important to address the underlying mechanisms of this deficit in future work.
精神分裂症患者共情的元分析。通常,研究采用人际关系自我报告问卷,共情特质是关系发展和维持不可或缺的组成部分,共情量表包括幻想、换位思考和个人。因此,这种能力的损害会对生活的许多领域产生不利影响,包括社会、性和婚姻。先前的综述表明,在精神分裂症中,这种能力受到损害,但存在大量异质性,有待更彻底地探索。考虑到这一点,我们的目标是使用荟萃分析方法综合大量文献,检查先前综述中观察到的异质性的来源,并发展精神分裂症移情缺陷的分类。使用随机效应模型计算认知共情和情感共情的对冲系数g。对关键的认知、临床和人口风险及保护因素进行meta回归模型分析。这些因素包括:出版年份、年龄、性别、种族、教育程度、一般智商、言语/发病前智商、整体神经认知、精神分裂症的阳性、阴性和一般症状、精神分裂症诊断时的年龄、疾病持续时间和药物对认知和情感共情的影响。文献检索显示有39项独立研究在精神分裂症中检查了em- pathy。健康对照组的得分高于精神分裂症患者,情感共情的效应值较小(赫奇斯的g = 0.29),认知共情的效应值中等(赫奇斯的g = 0.53)。两种成分都是异质的。使用元回归模型的分析发现,诊断时的年龄和疾病持续时间调节了认知共情效应大小的差异,因此,与健康对照组相比,诊断较早或病程较慢的患者在认知共情方面表现出更大的困难。我们发现较长的病程和较年轻的临床诊断年龄增强了严重和持久精神分裂症患者的认知共情障碍。对于情感共情,我们得出结论,与健康对照相比,一些患者报告有缺陷[即情感共情较低],其他人报告相当水平,其余报告经历更高的情绪唤醒。由于早期诊断,病程延长和日功能情绪反应是共情互动不良的重要危险因素,因此在未来的工作中,解决这一缺陷的潜在机制将是重要的。
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引用次数: 2
The Self: Can Behaviorism Inform the Study of The Self? 自我:行为主义能指导自我研究吗?
Pub Date : 2019-05-06 DOI: 10.24966/PDA-0150/100021
G. Hunter
Burrhus Frederic Skinner’s discussion of Self-Control begins with the explanation of its implicit nature in establishing relations between stimuli and responses. In functional analysis an independent variable operates as a means of controlling a behavior response for either an analyst or individual. This phenomenon is the focus of experimental science and validating the relational effect is the objective of behaviorist study. Regarding individuals controlling their own behavior their issue of responsibility is of relevance. A major part of adolescent development is learning to take responsibility for his or her self. The learning process coincides with biological, social, and psychological developments that must be navigated with care to avoid negative effects on the individual’s self-concept and self-efficacy (belief in one’s capacity to function competently). Developing a behavior response repertoire to environmental stimuli is a moment to moment endeavor that Skinner acknowledges but insists on focusing on the behavior and not the behaving individual. By discriminating between stimuli and altering environmental circumstances organisms behave. Citation: Hunter G (2019) The Self: Can Behaviorism Inform the Study of The Self?. J Psychiatry Depress Anxiety 5: 021.
伯勒斯·弗雷德里克·斯金纳(Burrhus Frederic Skinner)对自我控制的讨论首先解释了自我控制在建立刺激和反应之间关系时的内隐性质。在功能分析中,自变量作为控制分析师或个人行为反应的手段。这种现象是实验科学关注的焦点,而验证这种关系效应是行为主义研究的目标。关于个人控制自己的行为,他们的责任问题是相关的。青少年发展的一个主要部分是学习为自己负责。学习过程与生理、社会和心理的发展相一致,必须小心地引导,以避免对个人的自我概念和自我效能产生负面影响(相信自己有能力胜任工作)。斯金纳承认,发展对环境刺激的行为反应库是一种时时刻刻的努力,但他坚持关注行为,而不是行为个体。生物体的行为是通过区分刺激和改变环境来实现的。引用本文:Hunter G(2019)《自我:行为主义能否为自我研究提供信息?》中华精神病学杂志(英文版)5:021。
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引用次数: 0
Adolescents’ Understanding of The Dynamics of Depression 青少年对抑郁动态的理解
Pub Date : 2019-05-06 DOI: 10.24966/PDA-0150/100017
S. Harter
Adolescents’ Understanding of the Dynamics of De- pression. J Depress Anxiety 5: 017. Abstract In recent decades, a variety of new methodologies have been applied by researchers to our understanding of depression in children and adolescence. New statistical techniques (path-analyses, sequential analyses, etc.) have examined more complex models that focus on the causes, correlates, and consequences of depression. New multi-dimensional questionnaires have also been developed
青少年对抑郁动力学的理解。[J] .心理与心理学报,5:017。近几十年来,研究人员应用了各种新的方法来理解儿童和青少年的抑郁症。新的统计技术(路径分析、序列分析等)检验了更复杂的模型,这些模型关注抑郁症的原因、相关性和后果。还编制了新的多维调查问卷
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引用次数: 0
Assessment of the Quality of Life of Young Men Suffering From Epilepsy 青年男性癫痫患者的生活质量评估
Pub Date : 2019-05-06 DOI: 10.24966/PDA-0150/100018
A. Voitiuk
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引用次数: 0
Dose Positive CHD8 have a Role in Ketogenic Diet Response in Autism: A Case Report 剂量阳性CHD8在自闭症生酮饮食反应中起作用:1例报告
Pub Date : 2018-07-21 DOI: 10.24966/PDA-0150/100012
Citation: AlQassmi A, AlOtiabi M, AlRabeeah F (2018) Dose Positive CHD8 have a Role in Ketogenic Diet Response in Autism: A Case Report. J Psychiatry Depress Anxiety 4: 012. Abstract Autism is a brain disorder that limits a person’s ability to commu-nicate and relate to other people. The symptoms of autism spectrum disorder are poorly treated with current medications. Symptoms of autism spectrum disorder are frequently co-morbid with a diagnosis of epilepsy. Ketogenic diets are remarkably effective in treatments for epilepsy in children in the same time there are several studies showed the effectiveness of ketogenic in Autism and behavior asso- ciated with it. This study tests the effects of ketogenic diet feeding in Autism and their behavior, a child with autism spectrum disorder. The child was started on ketogenic diet formulas starting at 5 years of age, diet protocols continued and performance of tests of sociability and repetitive behavior was assessed. A ketogenic diet improved behavioral characteristics of autism spectrum disorder. Ketogenic diet feeding improved multiple measures of sociability and reduced repetitive behavior in autism child. Positive gene mutation of autism may be an important factors in showing the response of high lipid diet in those children.
引用本文:AlQassmi A, AlOtiabi M, AlRabeeah F(2018)剂量阳性CHD8在自闭症生酮饮食反应中的作用:一个病例报告。[J] .心理与精神病学杂志。自闭症是一种脑部疾病,它限制了一个人与他人交流和联系的能力。目前的药物治疗对自闭症谱系障碍的症状治疗不力。自闭症谱系障碍的症状经常与癫痫的诊断共病。生酮饮食在治疗儿童癫痫方面非常有效,同时有几项研究表明生酮对自闭症及其相关行为的有效性。本研究测试了生酮饮食喂养对自闭症及其行为的影响,一个自闭症谱系障碍儿童。该儿童从5岁开始使用生酮饮食配方,继续进行饮食方案,并评估社交能力和重复行为测试的表现。生酮饮食改善自闭症谱系障碍的行为特征。生酮饮食喂养改善了自闭症儿童的社交能力,减少了重复行为。自闭症阳性基因突变可能是高脂饮食对自闭症儿童产生影响的重要因素。
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引用次数: 3
Sex Differences in Anxiety Disorders: A Review 焦虑症的性别差异:综述
Pub Date : 2018-07-21 DOI: 10.24966/PDA-0150/100011
Isha Jalnapurkar
Women have consistently shown to be more likely than men to meet criteria for the diagnosis of an anxiety disorder during their lifetime. Prior research has demonstrated that presence of an anxiety disorder confers significant risk for the subsequent development of other psychiatric disorders including another anxiety disorder and major depression. Studies investigating this increased vulnerability to and burden of illness in women have implicated the role of female reproductive hormones and related cycles, physiologic differences leading to differences in symptomatology and metabolism and response to psychotropic medications. There is also evidence of differences in brain structures responsible for anxiety and panic related circuitry. In spite of these noteworthy differences, there are limited systematic reports describing the effects of biological sex on the development, course, comorbidity, and response to treatment of anxiety disorders. In this article, we provide a review of existing literature describing the unique characteristics of primary anxiety disorders in women, including Generalized Anxiety Disorder (GAD), Social Anxiety Disorder (SAD), and Panic Disorder (PD). We have incorporated the changes in nosology made in the DSM-5 and have reviewed available data on the potential impact of sex on the epide- miology, phenomenology, course, and treatment response of these anxiety disorders. We also provide a brief overview of the potential genetic and neurobiological factors, discuss biological sex differences in medication metabolism and the potential relevance of these dif- ferences in the pharmacologic management of women with anxiety disorders.
一直以来,女性比男性更有可能在一生中达到焦虑症的诊断标准。先前的研究表明,焦虑障碍的存在会给其他精神疾病的后续发展带来重大风险,包括另一种焦虑障碍和重度抑郁症。对妇女疾病易感性和疾病负担增加的研究表明,女性生殖激素和相关周期的作用、导致症状和代谢差异的生理差异以及对精神药物的反应。也有证据表明,负责焦虑和恐慌相关回路的大脑结构存在差异。尽管存在这些值得注意的差异,但描述生理性别对焦虑症的发展、病程、共病和治疗反应的影响的系统报道有限。在这篇文章中,我们回顾了现有的文献,描述了女性原发性焦虑症的独特特征,包括广泛性焦虑症(GAD)、社交焦虑症(SAD)和恐慌症(PD)。我们纳入了DSM-5在分类学上的变化,并回顾了性别对这些焦虑症的流行病学、现象学、病程和治疗反应的潜在影响的现有数据。我们还简要概述了潜在的遗传和神经生物学因素,讨论了药物代谢的生物学性别差异以及这些差异在女性焦虑症药物管理中的潜在相关性。
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引用次数: 77
Community Gardening, Volunteerism and Personal Happiness: “Digging In” to Green Space Environments for Improved Health 社区园艺,志愿服务和个人幸福:“挖掘”绿色空间环境改善健康
Pub Date : 2018-07-21 DOI: 10.24966/pda-0150/100015
August John Hoffman
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引用次数: 2
Mental Health First Aid Act: A Policy Analysis 心理健康急救法案:政策分析
Pub Date : 2018-07-21 DOI: 10.24966/pda-0150/100013
S. Bhatta
Mental health is a critical part of overall wellness. Only 17% of United States adults are in a state of optimal mental health. Depression is the most common type of mental illness. Likewise, Major Depressive Disorder (MDD) is common in childhood and adolescence and is associated with functional impairment and suicide. Among teenagers and young adults, suicide was the second leading cause of death in 2013. Adolescents in foster care have considerably more psychiatric symptoms than their other counterparts. Mental health problems are also associated with gun violence. The purpose of this policy analysis paper is to emphasize the importance of different proposed bills and implemented policies for improving mental health outcomes. Several efforts have been made in the past to improve mental health care in the United States. The Affordable Care Act (ACA) provided opportunities for expanded access to behavioral health care and established mental health and substance abuse care as essential coverage. The Mental Health First Aid Act (MHFAA) was a bill introduced in Congress in order to improve awareness, identification, and ability to appropriately respond to the needs of persons experiencing symptoms of mental disorders. The goal of this act is to provide mental health first aid training to first responders. Mental health stigma is a significant barrier to participation in mental health care. Mental health first aid training can play a significant role in building community awareness and reducing stigma. Primary care providers can also play significant roles in early identification and establishment of care coordination of mental illnesses. The positive parenting programs that motivate parents to come and discuss their family issues without any fear or shame are advantageous in improving positive outcomes. Also, policies in reducing the scarcity of the mental health providers in all states and counties should be considered. Citation: Bhatta S (2018) Mental Health First Aid Act: A Policy Analysis. J Psychiatry Depress Anxiety 4: 013.
心理健康是整体健康的重要组成部分。只有17%的美国成年人处于最佳心理健康状态。抑郁症是最常见的精神疾病。同样,重度抑郁症(MDD)在儿童和青少年中很常见,并与功能障碍和自杀有关。在青少年和年轻人中,自杀是2013年的第二大死因。被寄养的青少年比其他同龄人有更多的精神症状。心理健康问题也与枪支暴力有关。本政策分析文件的目的是强调提出的不同法案和实施的政策对改善心理健康结果的重要性。过去,为了改善美国的精神卫生保健,已经做出了一些努力。《负担得起的医疗法案》(ACA)为扩大获得行为保健提供了机会,并将精神健康和药物滥用保健确立为基本覆盖范围。《精神健康急救法案》(MHFAA)是国会提出的一项法案,旨在提高认识、识别和适当应对有精神障碍症状的人的需求的能力。该法案的目的是为急救人员提供心理健康急救培训。精神卫生耻辱是参与精神卫生保健的一个重大障碍。精神卫生急救培训可以在建立社区意识和减少耻辱感方面发挥重要作用。初级保健提供者也可以在早期识别和建立精神疾病的护理协调方面发挥重要作用。积极的育儿计划鼓励父母来讨论他们的家庭问题,没有任何恐惧或羞耻,有利于改善积极的结果。此外,应考虑在所有州和县制定政策,以减少精神卫生服务提供者的短缺。引用本文:Bhatta S(2018)心理健康急救法案:政策分析。中华精神病学杂志(英文版)。
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引用次数: 1
The Medical Monopoly on Assisted Suicide 协助自杀的医疗垄断
Pub Date : 2018-07-21 DOI: 10.24966/PDA-0150/100014
J. Doomen
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引用次数: 0
Major Depressive Disorder and Condom Use in Young Adult Females. 年轻成年女性的重度抑郁症与安全套使用。
Pub Date : 2016-01-01 Epub Date: 2016-08-22 DOI: 10.24966/PDA-0150/100006
Tiffany Cooke, Gilberte Bastien, Junjun Xu, Jurine Owen, Kurstie Cunningham, George Rust

Major Depressive Disorder (MDD) is a leading cause of disability and can contribute to risky sexual behavior, potentially leading to Sexually Transmitted Infections (STIs).Young adult women face unique STI risks, along with gender prevalence for MDD.

Aim: The aim of this study is to assess the association between moderate to severe MDD and inconsistent condom use in U.S women aged 18-25.

Methods: We examined National Health and Nutrition Examination Survey (NHANES) data from 2011-2013 Our study focuses on responses to the depression screener and "sexual behavior" questions.

Results: A total of 302 women, aged 18-25 responded to the depression screener and the "never had sex without a condom question". Of these , 270 had no or mild MDD and 32 had moderate to severe MDD Of the women with moderate-severe MDD, 1 consistently used condoms, and 31 used condoms inconsistently. On both bivariate and multivariate analysis this association between moderate-severe MDD and inconsistent condom use was significant (p = .004, OR 10.260 95% Cl 1-371- 76.801 ) After using the complex samples module, this association remained significant, even after controlling for race (p = 0_032; OR = 7_677, 95% Cl = 1202-49.048).

Conclusion: Moderate-severe MDD is significantly associated with inconsistent condom use in 18-25 year-old women. This suggests a need for further research and interventions geared toward treating MDD, but also in counseling young adult women with MDD regarding healthy sexual behaviors.

重度抑郁症(MDD)是导致残疾的主要原因,并可能导致危险的性行为,潜在地导致性传播感染(sti)。年轻成年妇女面临独特的性传播感染风险,以及重度抑郁症的性别患病率。目的:本研究的目的是评估美国18-25岁女性中中度至重度重度抑郁症与不一致使用安全套之间的关系。方法:我们检查了2011-2013年国家健康与营养调查(NHANES)的数据。我们的研究重点是对抑郁症筛查和“性行为”问题的回答。结果:共有302名年龄在18-25岁之间的女性回答了抑郁症筛查和“从未在没有安全套的情况下发生过性行为”的问题。其中270人没有或轻度重度抑郁症,32人有中度至重度重度抑郁症。在中度至重度重度抑郁症的女性中,1人一直使用避孕套,31人不一直使用避孕套。在双变量和多变量分析中,中度重度重度抑郁症和不一致使用安全套之间的关联是显著的(p = 0.004, OR 10.260 95% Cl 1-371- 76.801)。在使用复杂样本模块后,即使在控制种族后,这种关联仍然显著(p = 0_032;OR = 7_677, 95% Cl = 1202-49.048)。结论:18-25岁女性中,中重度重度重度抑郁症与不一致使用安全套有显著相关性。这表明需要进一步的研究和干预措施,以治疗重度抑郁症,同时也需要就健康的性行为向患有重度抑郁症的年轻成年女性提供咨询。
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引用次数: 3
期刊
HSOA journal of psychiatry, depression & anxiety
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