Pub Date : 2023-04-13DOI: 10.29011/2574-3511.100090
Débora Gonçalves, Da Silva, Beatriz Francisco, Barbosa Rodrigues, Josue Da, Silva Brito, A. Amato, Debora Goncalves da Silva
) Predictors of Hepatic Fat Fraction Measured by Magnetic Resonance Imaging in Adults with Non-alcoholic Fatty Liver Disease
磁共振成像测量成人非酒精性脂肪肝患者肝脏脂肪分数的预测因素
{"title":"Predictors of Hepatic Fat Fraction Measured by Magnetic Resonance Imaging in Adults with Non-alcoholic Fatty Liver Disease","authors":"Débora Gonçalves, Da Silva, Beatriz Francisco, Barbosa Rodrigues, Josue Da, Silva Brito, A. Amato, Debora Goncalves da Silva","doi":"10.29011/2574-3511.100090","DOIUrl":"https://doi.org/10.29011/2574-3511.100090","url":null,"abstract":") Predictors of Hepatic Fat Fraction Measured by Magnetic Resonance Imaging in Adults with Non-alcoholic Fatty Liver Disease","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"35 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"78035735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-10DOI: 10.29011/2574-3511.100091
Tawbeh Hussien, El Zein Zeinab, Hachem Sara, Hallal Marwa, Alborz Haji, Jibaii Soukayna, Matar Rami, Hallal Mahmoud
The Sensitivity and the Specificity of the Fecal Immunochemical Testing in Detecting Colonic Cancerous and Precancerous Lesions among the Lebanese Population
黎巴嫩人群中粪便免疫化学检测结肠癌和癌前病变的敏感性和特异性
{"title":"The Sensitivity and the Specificity of the Fecal Immunochemical Testing in Detecting Colonic Cancerous and Precancerous Lesions among the Lebanese Population","authors":"Tawbeh Hussien, El Zein Zeinab, Hachem Sara, Hallal Marwa, Alborz Haji, Jibaii Soukayna, Matar Rami, Hallal Mahmoud","doi":"10.29011/2574-3511.100091","DOIUrl":"https://doi.org/10.29011/2574-3511.100091","url":null,"abstract":"The Sensitivity and the Specificity of the Fecal Immunochemical Testing in Detecting Colonic Cancerous and Precancerous Lesions among the Lebanese Population","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"50 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82259748","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-02-24DOI: 10.29011/2574-3511.100088
{"title":"Incidence, Diagnosis, and Management of Hepatocellular Carcinoma: Current Perspectives and Future Direction","authors":"","doi":"10.29011/2574-3511.100088","DOIUrl":"https://doi.org/10.29011/2574-3511.100088","url":null,"abstract":"","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-02-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75792238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-30DOI: 10.29011/2574-3511.100087
{"title":"Development of a Self-Report Questionnaire for Patients and their Families to Prevent Faecal Incontinence in Daily Life","authors":"","doi":"10.29011/2574-3511.100087","DOIUrl":"https://doi.org/10.29011/2574-3511.100087","url":null,"abstract":"","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"15 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90478224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-25DOI: 10.29011/2574-3511.100086
Noriyuki Arakawa, A. Irisawa, K. Ishida, Yoshiko, Yamaguchi, A. Yamabe, M. Eizuka, H. Wakabayashi
Our patient was a man in his eighties who was referred to our department after a screening endoscopy indicated some abnormalities. Upper gastrointestinal endoscopy identified a 6-mm submucosal tumor in the posterior wall of the lesser curvature
{"title":"A Case of Serotonergic Gastric Neuroendocrine Tumor with Fibrous Stroma an Unusual EUS Finding","authors":"Noriyuki Arakawa, A. Irisawa, K. Ishida, Yoshiko, Yamaguchi, A. Yamabe, M. Eizuka, H. Wakabayashi","doi":"10.29011/2574-3511.100086","DOIUrl":"https://doi.org/10.29011/2574-3511.100086","url":null,"abstract":"Our patient was a man in his eighties who was referred to our department after a screening endoscopy indicated some abnormalities. Upper gastrointestinal endoscopy identified a 6-mm submucosal tumor in the posterior wall of the lesser curvature","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"29 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81252953","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-11-10DOI: 10.29011/2574-3511.100085
{"title":"The Videocapsule Endoscopy Role in the Early Diagnosis of Small Bowel Melanoma Metastasis: A Particular “Coal Black” Endoscopic Appearance","authors":"","doi":"10.29011/2574-3511.100085","DOIUrl":"https://doi.org/10.29011/2574-3511.100085","url":null,"abstract":"","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88356508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-23DOI: 10.29011/2574-3511.100083
{"title":"Growth Failure, Micronutrient Deficiency and Autoimmunity – A New Phenotype of Hennekam Syndrome","authors":"","doi":"10.29011/2574-3511.100083","DOIUrl":"https://doi.org/10.29011/2574-3511.100083","url":null,"abstract":"","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81381395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-09-15DOI: 10.29011/2574-3511.100082
P. Zhu, Peiyao Shi, Leijing Duan, Xian Jin, Y. Tan, Fenfang, Lei, Qingxia Liu
Gene in Abstract: Chronic hepatitis B virus (HBV) infection is one of the major causes of hepatocellular carcinoma (HCC), and the HBV pre-S gene plays a critical role in the molecular pathogenesis of HBV-related HCC. We have investigated whether there are particular HBV pre-S gene mutations associated with HCC in patients from southern China. The HBV pre-S gene was examined in 100 paraffin-embedded tumor tissue and 100 paraffin-embedded paracancerous tissue samples from patients with HCC by nested polymerase chain reaction (PCR). The HBV pre-S genes with potentially important mutations from tumor tissue samples were sequenced and aligned with the published HBV pre-S gene sequence. Twelve patients (12.0%) had pre-S mutations; six had a pre-S1 deletion, one patient had a pre-S2_ deletion, five patients had both a pre-S deletion, and a pre-S2 mutation. Among them, two patients contained pre-S1 insertion and two patients contained pre-S1 start codon mutation. Two patients (2.0%) of hepatocellular carcinoma paracancerous tissue had pre-S mutation and two patients had pre-S1 + pre-S2 deletion. The pre-S sequence of HBV contained stop codon in four patients of HCC, leading to truncated pre-S protein and changed protein structure. These results suggest that HBV pre-S gene deletion mutation and insertion mutation in HCC tissues and paracancerous tissues lead to truncated HBV pre-S protein or protein changes, which may be related to the occurrence of hepatocellular carcinoma.
{"title":"Analysis of Hepatitis B Virus Pre-S Gene in Hepatocellular Carcinoma and Paracancerous Tissues from Southern China","authors":"P. Zhu, Peiyao Shi, Leijing Duan, Xian Jin, Y. Tan, Fenfang, Lei, Qingxia Liu","doi":"10.29011/2574-3511.100082","DOIUrl":"https://doi.org/10.29011/2574-3511.100082","url":null,"abstract":"Gene in Abstract: Chronic hepatitis B virus (HBV) infection is one of the major causes of hepatocellular carcinoma (HCC), and the HBV pre-S gene plays a critical role in the molecular pathogenesis of HBV-related HCC. We have investigated whether there are particular HBV pre-S gene mutations associated with HCC in patients from southern China. The HBV pre-S gene was examined in 100 paraffin-embedded tumor tissue and 100 paraffin-embedded paracancerous tissue samples from patients with HCC by nested polymerase chain reaction (PCR). The HBV pre-S genes with potentially important mutations from tumor tissue samples were sequenced and aligned with the published HBV pre-S gene sequence. Twelve patients (12.0%) had pre-S mutations; six had a pre-S1 deletion, one patient had a pre-S2_ deletion, five patients had both a pre-S deletion, and a pre-S2 mutation. Among them, two patients contained pre-S1 insertion and two patients contained pre-S1 start codon mutation. Two patients (2.0%) of hepatocellular carcinoma paracancerous tissue had pre-S mutation and two patients had pre-S1 + pre-S2 deletion. The pre-S sequence of HBV contained stop codon in four patients of HCC, leading to truncated pre-S protein and changed protein structure. These results suggest that HBV pre-S gene deletion mutation and insertion mutation in HCC tissues and paracancerous tissues lead to truncated HBV pre-S protein or protein changes, which may be related to the occurrence of hepatocellular carcinoma.","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80574407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-11DOI: 10.29011/2574-3511.100080
J. Louwers, I. N. B. Ilse, G. Raicu, B. Weusten
Radiofrequency ablation (RFA) preceded by endoscopic resection of visible lesions is the current standard of care for patients with early neoplastic Barrett’s esophagus (BE). Neoplastic recurrences after successful endoscopic treatment are rare, and the incidence of recurrence is highest in the first years of follow-up. However, studies evaluating long-term durability of endoscopic treatment in BE are lacking, with only few studies exceeding a median follow-up time of five years. Hereby we report on a case with a neoplastic recurrence 12 years after successful endoscopic treatment of dysplastic BE with RFA. The knowledge that neoplastic recurrences can occur even after more than a decade of initial treatment stresses the importance of long-term endoscopic follow-up with detailed inspection of the neosquamous mucosa.
{"title":"Late Recurrence after Successful Radiofrequency Ablation for Barrett’s Neoplasia: A Case Report","authors":"J. Louwers, I. N. B. Ilse, G. Raicu, B. Weusten","doi":"10.29011/2574-3511.100080","DOIUrl":"https://doi.org/10.29011/2574-3511.100080","url":null,"abstract":"Radiofrequency ablation (RFA) preceded by endoscopic resection of visible lesions is the current standard of care for patients with early neoplastic Barrett’s esophagus (BE). Neoplastic recurrences after successful endoscopic treatment are rare, and the incidence of recurrence is highest in the first years of follow-up. However, studies evaluating long-term durability of endoscopic treatment in BE are lacking, with only few studies exceeding a median follow-up time of five years. Hereby we report on a case with a neoplastic recurrence 12 years after successful endoscopic treatment of dysplastic BE with RFA. The knowledge that neoplastic recurrences can occur even after more than a decade of initial treatment stresses the importance of long-term endoscopic follow-up with detailed inspection of the neosquamous mucosa.","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75050623","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-08-03DOI: 10.29011/2574-3511.100079
{"title":"Frequency of Disagreement between Liver Ultrasound and Elastography in the Diagnosis of Cirrhosis","authors":"","doi":"10.29011/2574-3511.100079","DOIUrl":"https://doi.org/10.29011/2574-3511.100079","url":null,"abstract":"","PeriodicalId":91736,"journal":{"name":"Journal of digestive diseases and hepatology","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85654957","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}