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Physiological Characteristics of Surgical Patients With Obesity in Response to the 6-Min Walk Test 外科肥胖症患者在 6 分钟步行测试中的生理特征
Pub Date : 2024-06-01 DOI: 10.31189/2165-6193-13.2.36
Natalie A. Smith, Peter L Mclennan, G. Peoples
Overall health and fitness contribute to surgical experience and recovery. The aim of this study was to describe an array of physiological characteristics in a presurgical patient cohort with obesity as a function of their sustained walking speed. We performed a prospective single-center cohort study in Wollongong Hospital, Australia from 2016 to 2018. Patients (N = 293) with severe obesity completed a 6-min walk test and were classified as either slow or fast walkers according to the cut point of 0.9 m·s−1 (2 mph). These groups were compared for anthropometry, comorbidities, respiratory and cardiovascular physiology, blood biomarkers, patient-centered outcomes, and perception of effort. Slow walkers (n = 115; age 65 [63 to 67] years; mean [95% confidence interval]) and fast walkers (n = 178; age 54 [52 to 56]; P < 0.05) were not different in body weight but were different for body mass index (slow 43.2 [42.0 to 44.4] versus fast 41.1 [40.5 to 41.8]; P < 0.05). Cardiovascular disease and renal disease were more prevalent in slow walkers. Respiratory physiology reflective of restrictive lung disease (force vial capacity [L] slow 2.61 [2.45 to 2.77] versus fast 3.34 [3.19 to 3.47]; P < 0.05) was more common in slow walkers, who also reported higher dyspnea ratings. Resting cardiovascular characteristics were not different, although N-terminal pro-B-type natriuretic peptide levels were higher in the slow group (P < 0.05). Quality of recovery at postoperative day 30 was higher in the fast walking group. In this Australian cohort, patients with obesity undergoing nonbariatric surgery differed in their physiological profiles according to walking speed. This study supports the need to appreciate the physical fitness of patients beyond simplified body weight and classification of obesity in the perioperative period.
整体健康和体能有助于手术体验和康复。本研究旨在描述肥胖症术前患者队列中的一系列生理特征,并将其作为持续步行速度的函数。 我们于 2016 年至 2018 年在澳大利亚卧龙岗医院进行了一项前瞻性单中心队列研究。重度肥胖患者(N = 293)完成了6分钟步行测试,并根据0.9米-秒-1(2英里/小时)的切点被分为慢走和快走两组。对这两组患者的人体测量、合并症、呼吸和心血管生理学、血液生物标志物、以患者为中心的结果以及对努力程度的感知进行了比较。 慢走者(n = 115;年龄 65 [63 至 67]岁;平均值 [95% 置信区间])和快走者(n = 178;年龄 54 [52 至 56];P < 0.05)在体重方面没有差异,但在体重指数方面存在差异(慢走者为 43.2 [42.0 至 44.4],快走者为 41.1 [40.5 至 41.8];P < 0.05)。心血管疾病和肾脏疾病在慢走者中更为普遍。慢走者的呼吸生理反映出限制性肺部疾病(力瓶容量[L],慢走者为 2.61 [2.45 至 2.77],快走者为 3.34 [3.19 至 3.47];P < 0.05)更常见,他们的呼吸困难评级也更高。虽然慢速组的 N 端前 B 型钠尿肽水平更高(P < 0.05),但静息心血管特征并无差异。快走组在术后第 30 天的恢复质量更高。 在这个澳大利亚队列中,接受非减肥手术的肥胖症患者的生理特征因步行速度而异。这项研究证明,在围手术期,除了简化体重和肥胖分类外,还需要了解患者的体能状况。
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引用次数: 0
Cardiorespiratory Effects of Tai Chi Versus Walking: Exploratory Data from the LEAP Trial 太极拳与步行的心肺效应:来自 LEAP 试验的探索性数据
Pub Date : 2024-06-01 DOI: 10.31189/2165-6193-13.2.52
Stephen A. Maris, Yan Ma, D. Litrownik, Marilyn L. Moy, Roger B. Davis, Peter M. Wayne, Gloria Y. Yeh
Tai Chi (TC), a mind-body exercise, may be a potential exercise maintenance strategy for patients with chronic obstructive pulmonary disease (COPD) after pulmonary rehabilitation. We sought to characterize the acute cardiorespiratory response during TC versus walking in patients with COPD after a 24-week intervention. Cardiorespiratory data were available on 26 adults with COPD (46% female, 54% GOLD stage III–IV) randomized to TC (n = 19) or group walking (n = 7). At 24 weeks, we examined between-groups standard cardiorespiratory measures (heart rate (HR), oxygen consumption (VO2), expired carbon dioxide (VCO2), respiratory rate (RR), and ventilation (VE)) during a multiphase in-class characterization protocol. Continuous HR data during resting and exercise phases were analyzed for time- and frequency-domain HR variability (HRV) indices. At 24 weeks, during exercise phases, those in TC exhibited a mean HR of 80 ± 15 b · min−1, RR of 16.5 ± 4 breaths·min−1, and VO2 of 434.8 ± 146.5 mL·min−1; and in walking 95.7 ± 9.2 b·min −1, 26.2 ± 8 breaths·min−1, and 901.3 ± 261.2 mL·min−1, respectively (P < 0.05). Overall, TC was less strenuous with lower HR, VO2, VCO2, RR, and VE (P < 0.05). At rest, TC demonstrated more favorable respiratory efficiency (VE/VCO2; 35.53 ± 5.65 versus 41.07 ± 5.21, P < 0.05). During the postexercise recovery phase, time-domain HRV indices decreased after walking (e.g., pNN20: 35.7 ± 24.1 baseline, 10.3 ± 9.5 postwalk; pNN50: 20.9 ± 18.5 baseline, 3.9 ± 3.7 postwalk), while they remained relatively unchanged after TC. Frequency-domain HRV measures suggested greater total power (TP) across all phases of TC versus walking, particularly during meditation (P < 0.05 for LnTP). Preliminary data support that TC may be associated with improved pulmonary efficiency and reduced rapid shallow breathing compared with walking and be a viable exercise maintenance option after pulmonary rehabilitation.
太极拳(TC)是一种心身运动,可能是慢性阻塞性肺病(COPD)患者在肺康复后的一种潜在运动维持策略。我们试图描述慢性阻塞性肺病患者在进行为期 24 周的干预后,在打太极拳和步行过程中的急性心肺反应。 我们获得了 26 名慢性阻塞性肺病成人患者(46% 为女性,54% 为 GOLD III-IV 期)的心肺功能数据,这些患者被随机分配到 TC(19 人)或集体步行(7 人)。在 24 周时,我们在多阶段课内特征描述方案中检查了组间标准心肺功能指标(心率 (HR)、耗氧量 (VO2)、呼出二氧化碳 (VCO2)、呼吸频率 (RR) 和通气量 (VE))。对静息和运动阶段的连续心率数据进行了时域和频域心率变异性(HRV)指数分析。 24 周时,在运动阶段,TC 组的平均心率为 80 ± 15 b - min-1,RR 为 16.5 ± 4 次呼吸-min-1,VO2 为 434.8 ± 146.5 mL-min-1;步行组的平均心率为 95.7 ± 9.2 b-min-1,RR 为 26.2 ± 8 次呼吸-min-1,VO2 为 901.3 ± 261.2 mL-min-1(P < 0.05)。总体而言,TC 的体力消耗较小,HR、VO2、VCO2、RR 和 VE 均较低(P < 0.05)。休息时,TC 表现出更高的呼吸效率(VE/VCO2;35.53 ± 5.65 对 41.07 ± 5.21,P <0.05)。在运动后恢复阶段,步行后时域心率变异指数下降(例如,pNN20:35.7 ± 24.1 基线,步行后 10.3 ± 9.5;pNN50:20.9 ± 18.5 基线,步行后 3.9 ± 3.7),而 TC 后则保持相对不变。频域心率变异测量结果表明,TC 与步行相比,各阶段的总功率(TP)都更大,尤其是在冥想期间(LnTP 的 P < 0.05)。 初步数据表明,与步行相比,TC 可提高肺效率,减少快速浅呼吸,是肺康复后一种可行的运动维持方式。
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引用次数: 0
Stroke, Step Count, and Alzheimer’s 中风、步数和老年痴呆症
Pub Date : 2024-06-01 DOI: 10.31189/2165-6193-13.2.65
Jonathan K. Ehrman, Elizabeth O'Neill
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引用次数: 0
Effective Manuscript Writing: A Learned Process 有效的手稿写作:一个学习的过程
Pub Date : 2024-06-01 DOI: 10.31189/2165-6193-13.2.35
Jonathan K. Ehrman
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引用次数: 0
Effects of 12 Months of Kettlebell Training on an Individual with Myasthenia Gravis 12 个月壶铃训练对肌无力患者的影响
Pub Date : 2024-06-01 DOI: 10.31189/2165-6193-13.2.61
D. Mazala, Morgan T. Fique, Andrea T. Barton, Karla A. Kubitz, Kathleen R. Dondero, Nicolas D. Knuth
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引用次数: 0
ECG Characteristics of Young High School Athletes in Northwest Florida 佛罗里达州西北部年轻高中运动员的心电图特征
Pub Date : 2024-06-01 DOI: 10.31189/2165-6193-13.2.44
Ludmila Cosio Lima, Licheng Lee, Armaghan Mahmoudian, L. Adlof, Youngil Lee
Sudden cardiac death in young athletes is a rare and tragic occurrence. A preparticipation physical examination (PPE) is widely used to identify athletes who might be at risk of sudden cardiac death. High school athletes in Escambia, Okaloosa, Santa Rosa, and Walton counties in Florida undergo annual sports physicals through a local sports medicine outreach program. A resting electrocardiogram (ECG) was implemented during the 2022 PPE. The aim of this study was to document the efficacy of implementing ECGs and to highlight the cardiac abnormalities identified in young athletes as part of a 1-d PPE. In total, 1,357 high school athletes (males = 879 and females = 478; age, 15.1 ± 1.3 years) completed a resting 12-lead ECG. These were interpreted by cardiologists using the International Criteria, with abnormal results being further investigated before final sports clearance. Descriptive statistics regarding ECG findings were analyzed. Twenty-three ECGs (1.7%) were classified as “abnormal” and were referred for further testing. Of these, 14 athletes were cleared to participate in sports, and 6 declined further evaluation. Three athletes, all males, were not cleared for sports participation. Of these, 2 athletes presented with Wolf-Parkinson-White syndrome (0.15%), and 1 athlete (0.10%) presented with dilated cardiomyopathy. Adding ECG screening as part of a single-day PPE can be used as a tool in identifying cardiac abnormalities among young athletes. To our knowledge, this is the highest number of athletes screened during a PPE in 1 d nationwide.
年轻运动员发生心脏性猝死是一种罕见的悲剧。参赛前体检 (PPE) 被广泛用于识别可能有心脏性猝死风险的运动员。佛罗里达州埃斯坎比亚县、奥卡卢萨县、圣罗莎县和沃尔顿县的高中运动员每年都会通过当地的运动医学推广计划进行运动体检。在 2022 年的 PPE 期间进行了静息心电图 (ECG)。本研究的目的是记录实施心电图的效果,并强调作为 1-D PPE 的一部分在年轻运动员中发现的心脏异常。 共有 1,357 名高中运动员(男 = 879 人,女 = 478 人;年龄为 15.1 ± 1.3 岁)完成了静息 12 导联心电图检查。心电图由心脏病专家根据国际标准进行解读,异常结果将在最终运动许可前进行进一步调查。对心电图结果进行了描述性统计分析。 有 23 张心电图(1.7%)被归类为 "异常",需要进行进一步检查。其中,14 名运动员获准参加运动,6 名运动员拒绝进一步评估。三名运动员(均为男性)未被批准参加体育运动。其中,2 名运动员患有沃尔夫-帕金森-怀特综合征(0.15%),1 名运动员患有扩张型心肌病(0.10%)。 增加心电图筛查作为单日PPE的一部分,可作为识别年轻运动员心脏异常的工具。据我们所知,这是全国范围内单日PPE筛查运动员人数最多的一次。
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引用次数: 0
THE EFFECTIVENESS OF PROGRESSIVE RESISTANCE TRAINING IN MANAGING PROGRESSIVE SUPRANUCLEAR PALSY: A CASE STUDY 渐进式阻力训练在控制进行性核上性麻痹中的有效性:案例研究
Pub Date : 2024-05-01 DOI: 10.31189/2165-7629-13-s2.401
Ms Tess Hawkins, Ms Ella Cooper, Ms Kate Williamson, Ms Taylah Pepper, A/Prof John Cullen, A/Prof Louise Waite
The Centre for STRONG Medicine is an outpatient multidisciplinary geriatric service at Concord Hospital, Sydney. An 82-year-old male with a primary diagnosis of Progressive Supranuclear Palsy (PSP) with cardiac and metabolic comorbidities was referred in March 2023. PSP is a rare neurological disorder that affects gait, balance, vision, and cognition. The participant mobilised with a rollator and had previously sustained vertebral and wrist fractures secondary to falls. Management was to use progressive resistance training (PRT) to combat mobility decline, prevent falls and provide education to encourage independent exercise. Initial assessment determined current health status using Falls Self Efficacy Scale (FSE-I) and Fried Frailty Phenotype (FFP) questionnaires, and measured function and strength using maximal gait speed, five times sit-to-stand (5xSTS) and one repetition maximum (1RM), respectively. FSE-I determined a high fear of falling and FFP determined frail classification. Outcomes informed the PRT exercise prescription targeting the major muscle groups for 2-3 sets of 7-9 repetitions at 70-85% 1RM progressed gradually and preformed twice weekly in a supervised group. Education regarding breathing, exercise tempo, rest, progression, and risk mitigation were provided. All outcomes were reassessed after 12-weeks of training. Attendance was 100% (23 sessions) with improvement in all outcomes. Functional improvements included 0.25metres/second increase in maximal gait speed, 2.5 second reduction in 5xSTS, and safe mobilisation without a rollator. Strength improvements included 101% increase in 1RM leg press, 100% increase in 1RM triceps extension and 72% increase in 1RM seated row. Frailty status improved to pre-frail and fear of falling reduced. Self-reported improvements included increased steadiness and confidence exercising unsupervised. Although PSP is progressive, PRT resulted in meaningful benefits in strength and function that improved daily task performance and confidence. Further research is needed to investigate the effects of PRT on PSP management in a larger cohort.
STRONG 医学中心是悉尼协和医院(Concord Hospital)的一个多学科老年病门诊服务机构。2023 年 3 月,一名 82 岁的男性患者被转诊至该中心,其主要诊断为进行性核上性麻痹(PSP),并伴有心脏和代谢方面的合并症。PSP 是一种罕见的神经系统疾病,会影响步态、平衡、视力和认知能力。该患者使用滚动器移动,之前曾因跌倒导致椎骨和腕骨骨折。 治疗方法是使用渐进阻力训练(PRT)来对抗活动能力下降、预防跌倒并提供教育以鼓励独立锻炼。初步评估使用跌倒自我效能量表(FSE-I)和弗里德虚弱表型(FFP)问卷确定了患者目前的健康状况,并分别使用最大步速、五倍坐立(5xSTS)和一次重复最大重量(1RM)测量了患者的功能和力量。FSE-I 确定了高度的跌倒恐惧,FFP 确定了虚弱的分类。研究结果为 PRT 运动处方提供了参考,该处方以主要肌肉群为目标,以 70-85% 的 1RM 进行 2-3 组 7-9 次重复,循序渐进,每周两次在有监督的小组中进行。此外,还提供了有关呼吸、运动节奏、休息、进步和降低风险的教育。训练 12 周后,对所有结果进行重新评估。 参加率为 100%(23 次),所有结果均有所改善。功能改善包括最大步速提高了 0.25 米/秒,5xSTS 缩短了 2.5 秒,以及在不使用滚轮的情况下安全移动。力量改善包括 1RM 压腿增加了 101%,1RM 三头肌伸展增加了 100%,1RM 坐姿划船增加了 72%。虚弱状况改善至虚弱前,对跌倒的恐惧减少。自我报告的改善包括在无人监督的情况下锻炼时的稳定性和自信心得到增强。 虽然帕金森病是渐进性的,但 PRT 在力量和功能方面带来了有意义的益处,改善了日常工作表现和信心。还需要进一步的研究,以便在更大的群体中调查 PRT 对 PSP 管理的影响。
{"title":"THE EFFECTIVENESS OF PROGRESSIVE RESISTANCE TRAINING IN MANAGING PROGRESSIVE SUPRANUCLEAR PALSY: A CASE STUDY","authors":"Ms Tess Hawkins, Ms Ella Cooper, Ms Kate Williamson, Ms Taylah Pepper, A/Prof John Cullen, A/Prof Louise Waite","doi":"10.31189/2165-7629-13-s2.401","DOIUrl":"https://doi.org/10.31189/2165-7629-13-s2.401","url":null,"abstract":"\u0000 \u0000 The Centre for STRONG Medicine is an outpatient multidisciplinary geriatric service at Concord Hospital, Sydney. An 82-year-old male with a primary diagnosis of Progressive Supranuclear Palsy (PSP) with cardiac and metabolic comorbidities was referred in March 2023. PSP is a rare neurological disorder that affects gait, balance, vision, and cognition. The participant mobilised with a rollator and had previously sustained vertebral and wrist fractures secondary to falls.\u0000 \u0000 \u0000 \u0000 Management was to use progressive resistance training (PRT) to combat mobility decline, prevent falls and provide education to encourage independent exercise. Initial assessment determined current health status using Falls Self Efficacy Scale (FSE-I) and Fried Frailty Phenotype (FFP) questionnaires, and measured function and strength using maximal gait speed, five times sit-to-stand (5xSTS) and one repetition maximum (1RM), respectively. FSE-I determined a high fear of falling and FFP determined frail classification. Outcomes informed the PRT exercise prescription targeting the major muscle groups for 2-3 sets of 7-9 repetitions at 70-85% 1RM progressed gradually and preformed twice weekly in a supervised group. Education regarding breathing, exercise tempo, rest, progression, and risk mitigation were provided. All outcomes were reassessed after 12-weeks of training.\u0000 \u0000 \u0000 \u0000 Attendance was 100% (23 sessions) with improvement in all outcomes. Functional improvements included 0.25metres/second increase in maximal gait speed, 2.5 second reduction in 5xSTS, and safe mobilisation without a rollator. Strength improvements included 101% increase in 1RM leg press, 100% increase in 1RM triceps extension and 72% increase in 1RM seated row. Frailty status improved to pre-frail and fear of falling reduced. Self-reported improvements included increased steadiness and confidence exercising unsupervised.\u0000 \u0000 \u0000 \u0000 Although PSP is progressive, PRT resulted in meaningful benefits in strength and function that improved daily task performance and confidence. Further research is needed to investigate the effects of PRT on PSP management in a larger cohort.\u0000","PeriodicalId":92070,"journal":{"name":"Journal of clinical exercise physiology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141045409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
IMPROVING SPORT SCIENCE IMPACT IN ATHLETE-LED PRACTICE ENVIRONMENTS: A PERSEPCTIVE FROM TRACK CYCLING 提高运动科学在运动员主导的实践环境中的影响力:田径自行车运动的视角
Pub Date : 2024-05-01 DOI: 10.31189/2165-7629-13-s2.458
Dr Antony Stadnyk, Prof Franco Impellizzeri, Dr Jamie Stanley, Dr Paolo Menaspà, Dr Katie Slattery
Like most high performance sports, track cyclists are typically supported within the training environment by coaches and interdisciplinary practitioners who, through evidence-based practices, guide the athlete through the process of performance development. To effectively impact practice and athlete performance, practitioners must be able to implement their knowledge and expertise in a way that complements the wider performance team. The aim of this study was to examine track cycling coaches’ perspectives of the role and impact of sport science and research on their practice and the athlete development process. Semi-structured interviews were conducted with elite track cycling coaches (n=8) who had been working at the highest level of the sport (Olympics, UCI World Championships). The interviews addressed factors contributing to athlete preparation, and the current and potential impact of sport science on the development of elite track cyclists. Reflexive thematic analysis was conducted to identify common themes in participants’ experiences and perspectives. Three principal themes were identified from the data: ‘conversation & the information dynamic’, highlighting the impact of information and feedback within the performance team for developing collective training intelligence; ‘integrating performance components for the individual’, detailing the importance of individualised and integrated approaches to athletes’ performance needs; and, ‘science to complement the vision’, examining the value of filtered data, and limitations of research in practice. The findings highlighted two key contributors to performance team effectiveness: athletes deeply invested in, and actively contributing to, the development process; and, performance staff identifying and filtering research and data to impact decision making and athlete development. A four-stage model was developed from the collective findings for guiding sport scientists’ impact in athlete-led practice environments. Additionally, the model outlines sport scientist-supportive actions for coaches and athletes, along with practice-supportive actions for researchers, to improve impact within the sport.
与大多数高水平运动一样,场地自行车运动员通常在训练环境中得到教练和跨学科从业人员的支持,他们通过循证实践指导运动员完成成绩发展过程。为了有效地影响实践和运动员的表现,从业人员必须能够以一种与更广泛的表现团队相辅相成的方式来实施他们的知识和专长。本研究旨在考察场地自行车教练员对运动科学和研究在其实践和运动员发展过程中的作用和影响的看法。 研究人员对在最高级别运动(奥运会、国际自行车联盟世界锦标赛)中工作过的场地自行车精英教练(人数=8)进行了半结构式访谈。访谈涉及运动员备战的因素,以及体育科学对精英场地自行车运动员发展的当前和潜在影响。我们进行了反思性主题分析,以确定参与者经验和观点中的共同主题。 从数据中确定了三个主要专题:对话与信息动态",强调了信息和反馈在成绩团队中对开发集体训练智慧的影响;"整合个人成绩要素",详细说明了针对运动员成绩需求的个性化和综合方法的重要性;以及 "科学补充愿景",考察了过滤数据的价值以及研究在实践中的局限性。 研究结果强调了提高运动队效率的两个关键因素:运动员对发展过程的深入投入和积极贡献;以及运动队工作人员对研究和数据的识别和筛选,以影响决策和运动员的发展。根据这些集体研究成果,我们建立了一个四阶段模型,用于指导体育科学家在运动员主导的实践环境中发挥影响。此外,该模式还概述了体育科学家支持教练员和运动员的行动,以及研究人员支持实践的行动,以提高在体育运动中的影响力。
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引用次数: 0
EXERCISE IS MEDICINE, BUT FOR WHAT? A MAPPING REVIEW OF PHYSICAL ACTIVITY RECOMMENDATIONS IN THE UK NICE CLINICAL GUIDELINES 运动是良药,但为了什么?英国好的临床指南中有关体育锻炼建议的绘图审查
Pub Date : 2024-05-01 DOI: 10.31189/2165-7629-13-s2.398
Matthew D Jones, Mr Avi Goodman, Michael C. Ferraro, Mr Harrison Hansford, James H McAuley
Clinical guidelines are used to inform best practice care, with research evidence a key aspect informing guideline recommendations. Physical activity is recommended for the management of a large variety of health conditions; however, the conditions that physical activity is recommended for has not been synthesised, nor has the quality of the evidence that informs these guideline recommendations. To understand the extent and type of evidence for physical activity recommendations across different health conditions in the UK National Institute for Health and Care Excellence (NICE) clinical guidelines. NICE was searched for clinical guidelines that recommended physical activity in the management/treatment of a health condition. Data relating to the condition, guideline date, physical activity recommendation(s) (general or specific), and evidence underpinning the recommendations was extracted. Where applicable, recommendations for research, priorities for implementation, and impact of the recommendations was also extracted. 221 clinical guidelines were reviewed, of which 52 provided one or more physical activity recommendations and were included in the analysis. The guidelines covered a range of conditions including cardiovascular, mental health, metabolic, neurological, musculoskeletal, and others. Most guidelines (n=43) provided general physical activity recommendations (e.g. advice to be active) whereas only 9 provided specific recommendations (e.g. type and dose of physical activity). The evidence underpinning the physical activity recommendations in the guidelines was mixed but was mostly based on very low-moderate quality evidence. Despite this, few guidelines recommended further research around physical activity. Physical activity is recommended in many clinical guidelines, demonstrating its perceived importance for improving health across a wide range of different conditions. The mostly low-quality evidence on which these recommendations are based questions why more guidelines do not recommend further high-quality research into physical activity. This would improve confidence in the evidence and hence confidence in the recommendations made by the guidelines.
临床指南用于指导最佳护理实践,而研究证据是指南建议的一个重要方面。体育锻炼被推荐用于多种健康状况的管理;然而,体育锻炼被推荐用于哪些健康状况,以及为这些指南建议提供依据的证据的质量如何,尚未进行综合分析。 了解英国国家健康与护理卓越研究所(NICE)临床指南中针对不同健康状况推荐体育锻炼的证据范围和类型。 在 NICE 中搜索了建议在管理/治疗某种健康状况时进行体育锻炼的临床指南。提取了与病症、指南日期、体育锻炼建议(一般或特定)以及建议所依据的证据相关的数据。在适用的情况下,还提取了研究建议、实施重点以及建议的影响。 共查阅了 221 份临床指南,其中 52 份提供了一项或多项体育锻炼建议并被纳入分析。这些指南涵盖了心血管、心理健康、代谢、神经、肌肉骨骼等一系列疾病。大多数指南(n=43)提供了一般性的体育锻炼建议(如建议积极锻炼),只有 9 份指南提供了具体建议(如体育锻炼的类型和剂量)。指南中体育锻炼建议所依据的证据参差不齐,但大多基于质量很低-中等的证据。尽管如此,很少有指南建议围绕体育锻炼开展进一步研究。 许多临床指南都建议进行体育锻炼,这表明体育锻炼对改善各种不同疾病的健康状况具有重要意义。这些建议所依据的大多是低质量的证据,这让人质疑为什么更多的指南不建议对体育锻炼进行进一步的高质量研究。这将提高人们对证据的信心,从而提高人们对指南所提建议的信心。
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引用次数: 0
ARE THERE NON-RESPONDERS TO HIIT IN CANCER SURVIVORS? CHANGES IN CARDIORESPIRATORY FITNESS, BODY COMPOSITION AND SYSTEMIC INFLAMMATION 癌症幸存者是否对 hiit 没有反应?心肺功能、身体成分和全身炎症的变化
Pub Date : 2024-05-01 DOI: 10.31189/2165-7629-13-s2.407
Alex Boytar, Dr Morgan Farley, Chloe Salisbury, Tina Skinner, Professor David Jenkins
High intensity interval training (HIIT) has been shown to elicit significant improvements in VO2peak in cancer survivors. Only 46-60% of healthy individuals are reported to respond to exercise interventions, though this rate has not been investigated in cancer survivors. AIMS: To determine the response rate in cancer survivors over 28-weeks of HIIT as measured by changes in cardiorespiratory fitness. Secondarily, the study aimed to observe associations between changes in cardiorespiratory fitness, body composition and inflammatory markers. 131 survivors of breast, prostate or colorectal cancer were observed over 28-weeks of HIIT (4x4 minutes; 85-95% HRpeak). VO2peak, body composition and markers of systemic inflammation were assessed at baseline, four-, 16- and 28-weeks. An improvement in VO2peak of 3.5 ml.kg-1.min-1 was used as a standard of minimal clinically important difference (MCID). Body composition was measured using DEXA, and inflammatory markers were assessed for each timepoint. 59.6% of participants improved their VO2peak greater than MCID (+3.5 ml.kg-1.min-1) and these individuals were retrospectively classified as responders. Responders showed improvements in VO2peak at four- and 16-weeks and maintained this change through to 28-weeks (0-4 weeks: +2.92 ml.kg-1.min-1, p<0.001; 0-16 weeks: +5.70 ml.kg-1.min-1, p<0.001; and 0-28 weeks: +5.30 ml.kg-1.min-1, p<0.001). No significant change in VO2peak was seen in non-responders (40.4%). Time since treatment, cancer type, and cancer treatment were all found to contribute to a model predicting VO2peak change (R=0.464, R2 = 21.5%., adj R2=16.1%, p<0.001). Body composition and inflammatory markers improved in response to training however were not associated with VO2peak change. HIIT elicited a MCID in VO2peak in almost 60% of cancer survivors. Independent to VO2peak change and cancer type, survivors showed significant favourable changes in inflammation and body composition in response to training.
高强度间歇训练(HIIT)已被证明能显著提高癌症幸存者的 VO2 峰值。据报道,只有 46-60% 的健康人对运动干预有反应,但这一比例尚未在癌症幸存者中进行调查。目的:根据心肺功能的变化,确定癌症幸存者在为期 28 周的 HIIT 运动中的反应率。其次,该研究旨在观察心肺功能、身体成分和炎症指标变化之间的关联。 研究人员对 131 名乳腺癌、前列腺癌或结直肠癌幸存者进行了为期 28 周的 HIIT(4x4 分钟;85-95% HRpeak)观察。分别在基线、4周、16周和28周时对VO2峰值、身体成分和全身炎症指标进行评估。以 VO2peak 提高 3.5 毫升/千克-1.分钟-1 作为最小临床意义差异(MCID)的标准。使用 DEXA 测量身体成分,并对每个时间点的炎症指标进行评估。 59.6%的参与者VO2峰值的改善幅度大于MCID(+3.5毫升.公斤-1.分钟-1),这些人被回顾性地归类为应答者。应答者在 4 周和 16 周时的 VO2peak 均有所改善,并将这一变化保持到 28 周(0-4 周:+2.92 毫升.千克/分钟-1):0-4周:+2.92 ml.kg-1.min-1,p<0.001;0-16周:+5.70 ml.kg-1.min-1,p<0.001:0-16周:+5.70 ml.kg-1.min-1,p<0.001;0-28周:+5.30 ml.kg-1.min-1,p<0.001:0-16 周:+5.70 毫升/千克-1.分钟-1,p<0.001;0-28 周:+5.30 毫升/千克-1.分钟-1,p<0.001)。无应答者(40.4%)的 VO2 峰值无明显变化。研究发现,治疗后时间、癌症类型和癌症治疗均有助于建立预测 VO2peak 变化的模型(R=0.464,R2=21.5%,adj R2=16.1%,p<0.001)。身体成分和炎症指标在训练后有所改善,但与 VO2peak 变化无关。 在近60%的癌症幸存者中,HIIT引起了VO2峰的MCID。与 VO2peak 变化和癌症类型无关,幸存者在训练后的炎症和身体成分发生了显著的有利变化。
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Journal of clinical exercise physiology
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