Zampieri Nicola, Cecchetto Mariangela, P. Simone, Vestri Elettra, Camoglio Francesco Saverio
Objective: Primary obstructive megaureter has always been considered a developmental defect. Surgical and conservative treatments were compared through a retrospective study first, and then in a longitudinal observational study. Materials and methods: Between January 1993 and January 2006 at our Department 42 cases of primitive obstructive megaureter were observed. Patients were divided into two groups: treated and untreated, each with inclusion and exclusion criteria. The efficacy of surgical treatment vs. conservative treatment was assessed through routine laboratory tests, ultrasound of the urinary tract and renal scintigraphy. Follow-up was at least 2 years for all patients.
{"title":"Primary Obstructive Megaureter in Children: to Treat or not?","authors":"Zampieri Nicola, Cecchetto Mariangela, P. Simone, Vestri Elettra, Camoglio Francesco Saverio","doi":"10.17352/AUR.000004","DOIUrl":"https://doi.org/10.17352/AUR.000004","url":null,"abstract":"Objective: Primary obstructive megaureter has always been considered a developmental defect. Surgical and conservative treatments were compared through a retrospective study first, and then in a longitudinal observational study. \u0000Materials and methods: Between January 1993 and January 2006 at our Department 42 cases of primitive obstructive megaureter were observed. Patients were divided into two groups: treated and untreated, each with inclusion and exclusion criteria. The efficacy of surgical treatment vs. conservative treatment was assessed through routine laboratory tests, ultrasound of the urinary tract and renal scintigraphy. Follow-up was at least 2 years for all patients.","PeriodicalId":92753,"journal":{"name":"Archive of urological research","volume":"78 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86932134","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. McClain, Lynne Sakowski, M. Conti, Hui Zhang, Q. K. Li
Intranuclear inclusions are important diagnostic features in many benign and malignant neoplasms. It has also been identified in major epithelial subtypes of renal cell carcinomas (RCCs), particularly in the chromophobe RCC. However, the finding in ccRCC has not been well studied. The finding of intranuclear inclusions may cause diagnostic difficulty, particularly in metastatic lesions. Herein, we reported a case of ccRCC with prominent intranuclear inclusions. The tumor also metastasized to local lymph nodes. Furthermore, in contrast to previous publications, we also found that intranuclear inclusions were immunoreactive with anti-PAX8 (paired box8) antibody. The potential diagnostic and clinical implications of intranuclear inclusions in ccRCC need to be addressed.
{"title":"Intranuclear Inclusions in Conventional Clear Cell Renal Cell Carcinoma (ccRCC): Diagnosis and Differential Diagnosis.","authors":"A. McClain, Lynne Sakowski, M. Conti, Hui Zhang, Q. K. Li","doi":"10.17352/AUR.000003","DOIUrl":"https://doi.org/10.17352/AUR.000003","url":null,"abstract":"Intranuclear inclusions are important diagnostic features in many benign and malignant neoplasms. It has also been identified in major epithelial subtypes of renal cell carcinomas (RCCs), particularly in the chromophobe RCC. However, the finding in ccRCC has not been well studied. The finding of intranuclear inclusions may cause diagnostic difficulty, particularly in metastatic lesions. Herein, we reported a case of ccRCC with prominent intranuclear inclusions. The tumor also metastasized to local lymph nodes. Furthermore, in contrast to previous publications, we also found that intranuclear inclusions were immunoreactive with anti-PAX8 (paired box8) antibody. The potential diagnostic and clinical implications of intranuclear inclusions in ccRCC need to be addressed.","PeriodicalId":92753,"journal":{"name":"Archive of urological research","volume":"197 1","pages":"5-7"},"PeriodicalIF":0.0,"publicationDate":"2018-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73110207","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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