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Minimally invasive approach for endometrial cancer: robotic assisted vs. straight stick laparoscopy 癌症的微创手术:机器人辅助与直杆腹腔镜
Pub Date : 2021-01-01 DOI: 10.21037/GPM-21-1
O. Raban, Y. Bukhari, W. Gotlieb
: The introduction of laparoscopic surgery in the early 1990’s presented an improved alternative to laparotomy, slowly shifting the surgical treatment for Endometrial Cancer (EC) toward minimally invasive surgery (MIS), with equivalent oncologic outcome and reduced perioperative morbidity. Robotic assisted surgery (RAS) introduced multiple technical improvements to straight stick laparoscopy (LS), associated with improved perioperative outcome including reduced blood loss, fewer conversions to laparotomy and shorter hospital stay, whereas other perioperative outcomes appear similar. Due to its technical advantages, adaptation of RAS involves a shorter learning curve than LS and offers improved ergonomics compared to straight stick instrumentation. The advantages of RAS are more pronounced in patients with increased body mass index (BMI). Both LS and RAS have been shown to be safe in elderly patients and although available data shows benefit compared to laparotomy, it does not suggest superiority of one MIS approach over the other. Even though RAS and LS have comparable oncologic outcomes, the integration of RAS facilitated the shift toward MIS, where LS had failed to significantly reduce the rate of laparotomy. This shift to MIS was associated with reduced postoperative length of stay and complication rates, offsetting the increased costs involved with RAS. By introducing a computer interface, RAS is allowing augmented reality and digital analysis, leading surgery towards precision surgery and a high-tech future.
:20世纪90年代初,腹腔镜手术的引入为剖腹手术提供了一种改进的替代方法,将癌症子宫内膜癌(EC)的手术治疗缓慢转向微创手术(MIS),具有同等的肿瘤结果和降低的围手术期发病率。机器人辅助手术(RAS)对直杆腹腔镜(LS)进行了多项技术改进,改善了围手术期的结果,包括减少了失血、减少了剖腹手术和缩短了住院时间,而其他围手术期结果似乎相似。由于其技术优势,RAS的适应需要比LS更短的学习曲线,并且与直杆仪器相比,提供了改进的人体工程学。RAS的优势在体重指数(BMI)增加的患者中更为明显。LS和RAS已被证明在老年患者中是安全的,尽管现有数据显示与剖腹手术相比是有益的,但这并不表明一种MIS方法优于另一种。尽管RAS和LS的肿瘤学结果相当,但RAS的整合促进了向MIS的转变,而LS未能显著降低剖腹手术率。这种向MIS的转变与术后住院时间和并发症发生率的减少有关,抵消了RAS增加的成本。通过引入计算机接口,RAS允许增强现实和数字分析,将外科手术推向精确外科和高科技的未来。
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引用次数: 0
The role of multiple bowel resections in advanced ovarian cancer: survival and surgical outcomes—a narrative review 多肠切除在晚期癌症中的作用:生存率和手术结果——叙述性综述
Pub Date : 2021-01-01 DOI: 10.21037/GPM-20-63
J. Casarin, V. Artuso, A. Cromi, F. Ghezzi
: Ovarian cancer (OC) is the fifth most common cancer-related cause of death in women and the most lethal gynecologic malignancies in developed countries. In more than two thirds of the cases it is diagnosed as an advanced stage disease. The treatment requires a surgical step, aiming to remove the macroscopically visible disease, either as a primary debulking surgery or interval debulking surgery (IDS) after neoadjuvant chemotherapy (NACT). In both cases radical, complex and invasive surgical procedures are needed in order to achieve complete resection of the tumor, frequently involving bowel surgery. Considering the spread of the disease in the abdominal cavity, involvement of multiple bowel segments is common. Multiple bowel resections (MBR) are often needed to a complete cytoreduction but are linked to a higher rate of bowel diversion and postoperative morbidity, including severe postoperative complications, as anastomotic leakage (AL), and even death. These complications not only affect short term morbidity but may even postpone the administration of adjuvant chemotherapy, thus significantly affecting the outcomes of the treatment. NACT may help reducing the aggressiveness of debulking surgery and therefore the rate of its complications. This strategy represents a valid therapeutic option, especially in fragile patients, reducing the surgical related morbidity and the risk of bowel resections, without affecting the overall survival.
卵巢癌是发达国家妇女死亡的第五大常见癌症相关原因,也是最致命的妇科恶性肿瘤。在超过三分之二的病例中,它被诊断为晚期疾病。治疗需要手术步骤,目的是去除宏观可见的疾病,作为初级减容手术或新辅助化疗(NACT)后的间隔减容手术(IDS)。在这两种情况下,为了实现肿瘤的完全切除,都需要激进、复杂和侵入性的外科手术,经常涉及肠手术。考虑到疾病在腹腔的扩散,累及多个肠段是常见的。多次肠切除术(MBR)通常需要完全减少细胞,但与较高的肠分流率和术后发病率相关,包括严重的术后并发症,如吻合口漏(AL),甚至死亡。这些并发症不仅影响短期发病率,甚至可能推迟辅助化疗的实施,从而显著影响治疗结果。NACT可能有助于减少减体积手术的侵袭性,从而减少并发症的发生率。这种策略是一种有效的治疗选择,特别是在虚弱的患者中,可以减少手术相关的发病率和肠切除术的风险,而不影响总体生存。
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引用次数: 0
Mesh vaginal colpopexy complications analysis—multicenter study results 补片阴道阴道固定术并发症分析-多中心研究结果
Pub Date : 2021-01-01 DOI: 10.21037/gpm-21-19
A. Popov, K. Abramyan, I. Klyushnikov, G. Kasyan
Department of Operative Gynecology and Oncogynecology with day hospital, Moscow Regional Scientific Research Institute of Obstetrics and Gynecology, Moscow, Russian Federation; Private Clinic Moscvorechye, Moscow, Russian Federation; Urology Department, Moscow State University of Medicine and Dentistry, Moscow, Russian Federation Contributions: (I) Conception and design: A Popov, K Abramyan; (II) Administrative support: A Popov, G Kasyan; (III) Provision of study materials or patients: A Popov, G Kasyan; (IV) Collection and assembly of data: K Abramyan, I Klyushnikov; (V) Data analysis and interpretation: I Klyushnikov, K Abramyan; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Karina Abramyan. Private Clinic Moscvorechye, Moscvorechye st. 16, Moscow, 115409, Russian Federation. Email: gyn_endoscopy@mail.ru.
俄罗斯联邦莫斯科,莫斯科地区妇产科科学研究所,妇科手术和肿瘤科,设有日间医院;莫斯科私人诊所,俄罗斯联邦莫斯科;俄罗斯联邦莫斯科国立医学和牙科大学泌尿系贡献:(I)概念和设计:A Popov,K Abramyan;(II) 行政支助:A Popov,G Kasyan;(III) 提供研究材料或患者:A Popov,G Kasyan;(IV) 收集和汇编数据:K Abramyan,I Klyushnikov;(V) 数据分析和解释:I Klyushnikov,K Abramyan;(VI) 手稿写作:所有作者;(VII) 手稿的最终批准:所有作者。通信:Karina Abramyan。莫斯科私人诊所,莫斯科,莫斯科大街16号,115409,俄罗斯联邦。电子邮件:gyn_endoscopy@mail.ru.
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引用次数: 0
A narrative review of the role of anaesthesia and peri-operative medicine in improving outcomes after surgery for advanced ovarian cancer 麻醉和围手术期药物在改善晚期卵巢癌症术后疗效中的作用的叙述性综述
Pub Date : 2021-01-01 DOI: 10.21037/gpm-21-28
Aimee Manicom, J. Pandit
Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK; Professor of Anaesthesia, University of Oxford, Oxford, UK Contributions: (I) Conception and design: JJ Pandit; (II) Administrative support: JJ Pandit; (III) Provision of study materials or patients: None; (IV) Collection and assembly of data: None; (V) Data analysis and interpretation: None; (VI) Manuscript writing: Both authors; (VII) Final approval of manuscript: Both authors. Correspondence to: Jaideep J. Pandit. Nuffield Department of Anaesthetics, Oxford University Hospitals NHS Foundation Trust, Oxford, UK. Email: jaideep.pandit@sjc.ox.ac.uk.
英国牛津大学医院NHS基金会纳菲尔德麻醉科;牛津大学麻醉学教授,牛津,英国贡献:(1)构思与设计:JJ Pandit;(二)行政支持:JJ Pandit;(三)提供研究材料或患者:无;(四)数据收集和汇编:无;(五)数据分析和解释:无;(六)稿件撰写:双方作者;(七)稿件最终审定:两位作者。通讯:Jaideep J. Pandit。英国牛津大学医院NHS基金会纳菲尔德麻醉科。电子邮件:jaideep.pandit@sjc.ox.ac.uk。
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引用次数: 1
The principles of safe and efficacious upper abdominal surgery 安全有效的上腹部手术原则
Pub Date : 2021-01-01 DOI: 10.21037/GPM-21-3
C. Fotopoulou, Ç. Taşkıran
: Upper abdominal debulking procedures represent an indispensable part of cytoreduction for advanced ovarian cancer. As a genuinely peritoneally disseminated malignancy, more than 70% of the patients will present in an advanced stage with tumor involvement of the upper abdominal organs, especially liver-and splenic capsule, lesser sac, Morrisons pouch and diaphragm. Studies have clearly shown the maximal survival benefit being derived from maximal effort surgery achieving total macroscopic tumor clearance. For that reason, gynecological oncology teams need to master the dissection techniques in the upper abdomen and also be able to handle the associated complications. We will review here the key issues around upper abdominal cytoreduction and focus on the spleen, liver, and stomach/lesser sac. Diaphragmatic surgery will be addressed in a separate, especially dedicated chapter. Safety and feasibility of complex oncologic upper abdominal dissections for advanced and relapsed ovarian cancer are based on the fundamental knowledge of anatomy, principles of peritonectomy techniques, as well as infrastructural support and collective knowledge and education of the entire team. Surgical and infrastructural expertise are of paramount importance to achieve best possible oncologic outcomes with an acceptable morbidity profile even for those patients with high burden disease.
:上腹部减瘤手术是晚期癌症细胞减少不可或缺的一部分。作为一种真正的腹膜播散性恶性肿瘤,超过70%的患者会出现在晚期,肿瘤累及上腹器官,尤其是肝和脾包膜、小囊、莫里森囊和横膈膜。研究清楚地表明,最大的生存效益来自于最大努力的手术,以实现宏观肿瘤的完全清除。因此,妇科肿瘤学团队需要掌握上腹部的解剖技术,并能够处理相关并发症。我们将在这里回顾有关上腹部细胞减少的关键问题,并重点关注脾脏、肝脏和胃/小囊。膈肌手术将在一个单独的,特别是专门的章节中讨论。晚期和复发性卵巢癌症复杂肿瘤上腹部解剖的安全性和可行性基于解剖学基础知识、腹膜切除术技术原理、基础设施支持以及整个团队的集体知识和教育。外科和基础设施专业知识对于实现最佳肿瘤学结果和可接受的发病率至关重要,即使对于那些患有高负担疾病的患者也是如此。
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引用次数: 3
Locally advanced cervical cancer treated with chemo-radiotherapy: a case report of a particular recurrence 局部晚期宫颈癌放化疗治疗:特殊复发1例报告
Pub Date : 2021-01-01 DOI: 10.21037/GPM-20-49
Luca Guaraldi, P. Pastina, P. Tini, M. Crociani, S. Marsili, V. Nardone
Adenocarcinoma of uterine cervix is usually treated with concurrent chemotherapy and external beam radiotherapy (EBRT), eventually followed by brachytherapy that can provide a good tumor control rate, although approximately one-third of the patients can develop further recurrence. The most common recurrence sites are the pelvis and the para-aortic nodes, with few patients having a single metastatic deposit. In this regard, precise definitions of recurrences and optimal treatment strategies are still to be clearly defined and currently there are no guidelines for the treatment of patients with oligometastatic cervical cancer. We present a case of an 81 years old patient with Stage IIB adenocarcinoma of uterine cervix, that was successfully treated with concurrent chemoradiotherapy with definitive intent. Six months later, she developed a solitary abdominal nodule for which she underwent resection followed by chemotherapy. At the present time there are no signs of local recurrence or distant metastasis after 3 years. In the case reported, the use of different strategies (radiotherapy, chemotherapy and surgery), as well as the correct choice and the timing of the different approaches has provided a great benefit for the patient. The use of surgery and chemotherapy in patients with recurrent cervical cancer is safe even in older patients with atypical
宫颈腺癌的治疗通常采用同步化疗和外束放疗(EBRT),最后进行近距离放疗,可提供良好的肿瘤控制率,尽管约三分之一的患者可进一步复发。最常见的复发部位是骨盆和主动脉旁淋巴结,很少有患者有单一的转移沉积。在这方面,复发的精确定义和最佳治疗策略仍有待明确界定,目前尚无治疗少转移性宫颈癌患者的指南。我们报告了一例81岁的IIB期子宫颈腺癌患者,并成功地进行了明确目的的同步放化疗。六个月后,她出现了一个孤立的腹部结节,她接受了切除和化疗。目前,3年后没有局部复发或远处转移的迹象。在报告的病例中,使用不同的策略(放疗,化疗和手术),以及正确的选择和不同方法的时机,为患者提供了很大的好处。对复发性宫颈癌患者进行手术和化疗是安全的,即使对非典型的老年患者也是如此
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引用次数: 0
Medicine and engineering collaboration in urogynecology: a narrative review 泌尿妇科的医学与工程合作:叙述性回顾
Pub Date : 2021-01-01 DOI: 10.21037/gpm-21-41
Q. Hu, Tao Wang, Yueyue Chen, Dongmei Wei, Tao Cui, L. Mei, Lin Zhang, Xiaoyu Niu
Laboratory of Molecular Translational Medicine, Centre for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Clinical Research Center for Birth Defects of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu, China; Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu, China Contributions: (I) Conception and design: All authors; (II) Administrative support: None; (III) Provision of study materials or patients: None; (IV) Collection and assembly of data: None; (V) Data analysis and interpretation: All authors; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. Correspondence to: Xiaoyu Niu. Department of Gynecology and Obstetrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China. Email: niuxy@scu.edu.cn; Lin Zhang. Laboratory of Molecular Translational Medicine, Centre for Translational Medicine, Key Laboratory of Birth Defects and Related Diseases of Women and Children (Sichuan University), Ministry of Education, Clinical Research Center for Birth Defects of Sichuan Province, West China Second University Hospital, Sichuan University, Chengdu 610041, China. Email: zhanglin@scu.edu.cn.
四川大学华西第二大学医院分子转化医学实验室,转化医学中心,出生缺陷及妇幼相关疾病教育部重点实验室,四川省出生缺陷临床研究中心,四川大学成都;四川大学华西第二医院妇产科(一)构思与设计:所有作者;行政支助:无;(三)提供研究材料或患者:无;(四)数据收集和汇编:无;(五)数据分析和解释:所有作者;(六)稿件撰写:全体作者;(七)稿件最终审定:全体作者。通讯作者:小雨牛。四川大学华西第二医院妇产科,四川成都610041电子邮件:niuxy@scu.edu.cn;林张。四川大学华西第二医院分子转化医学实验室,转化医学中心,出生缺陷及妇幼相关疾病教育部重点实验室,四川省出生缺陷临床研究中心,四川成都610041。电子邮件:zhanglin@scu.edu.cn。
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引用次数: 0
Laparoscopic TOT-like Burch colposuspension: a modification of the original to adapt to the future 腹腔镜式TOT-like Burch colpossuspension:对原来的改进以适应未来
Pub Date : 2021-01-01 DOI: 10.21037/gpm-21-21
R. Botchorishvili, A. Aleksandrov
: Urinary incontinence is a medical condition that decreases the quality of life of more than 35% of women worldwide and its incidence increases with age. Since their introduction in 1996, the transvaginal midurethral slings have become the treatment of choice for patients with stress urinary incontinence. In recent years the restriction of the United States Food and Drugs Administration over the transvaginal meshes for prolapse has generated considerable tension and debate over the synthetic protheses, applied to the patients via transvaginal route either for prolapse, or incontinence. Due to growing concerns over a complete ban of transvaginal tapes for incontinence in the future, gynecologists have rediscovered the Burch colposuspension for treatment of patients with incontinence. The procedure is living its renaissance and the goal of this article is to present our modification of the classical technique that we call TOT-like Burch colposuspension using a state-of-art laparoscopic approach. One of the drawbacks of the classic Burch procedure is the high rate of dysuric symptoms postoperatively, which in our modification is overcome, as the suspension of the bladder neck and the urethra includes also the pubourethral ligaments and the arcus tendinous fascia pelvis with a single suture, which provides the tension-free support resembling the effect of the TOT-tapes. The corresponding video is divided in different steps in order to make the procedure more comprehensive and reproducible. 5
尿失禁是一种医学疾病,使全世界35%以上的妇女的生活质量下降,其发病率随着年龄的增长而增加。自1996年引入以来,经阴道尿道中吊带术已成为治疗压力性尿失禁患者的首选方法。近年来,美国食品和药物管理局对经阴道脱垂的限制产生了相当大的紧张和争论的合成假体,应用于经阴道脱垂或尿失禁的患者。由于越来越多的人担心在未来完全禁止经阴道带治疗失禁,妇科医生重新发现了伯奇阴道悬吊来治疗失禁患者。该手术正在复兴,本文的目的是介绍我们对经典技术的修改,我们称之为TOT-like Burch colpossuspension使用最先进的腹腔镜方法。经典Burch手术的缺点之一是术后尿路障碍的发生率高,在我们的改进中克服了这一点,因为膀胱颈和尿道的悬吊也包括耻骨尿道韧带和骨盆腱束筋膜弧线,这提供了类似于tot胶带效果的无张力支撑。相应的视频被分成不同的步骤,以使该过程更加全面和可复制。5
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引用次数: 0
The role of exploratory laparoscopy in surgical planning for ultra- radical surgery for ovarian cancer: a narrative review 探索性腹腔镜在卵巢癌症超根治手术计划中的作用:叙述性综述
Pub Date : 2021-01-01 DOI: 10.21037/gpm-21-25
M. Morotti, G. Valenti, V. Mavroeidis, Tingyan Shi
Nuffield Department of Women’s & Reproductive Health, University of Oxford, Oxford, UK; Department of Gynaecology, University Hospital (CHUV), Lausanne, Switzerland; Department of General Surgery and Medical-Surgical Specialties, Institute of Obstetrics and Gynecology, University of Catania, Catania, Italy; Department of Hepatobiliary and Pancreatic Surgery, Oxford University Hospitals NHS Foundation Trust, Churchill Hospital, Oxford, UK; Division of Gynecological Oncology, Fudan University Zhongshan Hospital, Shanghai, China Contributions: (I) Conception and design: M Morotti, T Shi; (II) Administrative support: None; (III) Provision of study materials or patients: None; (IV) Collection and assembly of data: M Morotti, G Valenti; (V) Data analysis and interpretation: M Morotti, VK Mavroeidis, T Shi; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors. These authors contributed equally to this work. Correspondence to: Matteo Morotti. Nuffield Department of Women’s & Reproductive Health, University of Oxford, Oxford, UK. Email: drmorottimatteo@gmail.com.
英国牛津大学纳菲尔德妇女与生殖健康系;瑞士洛桑大学医院妇科;意大利卡塔尼亚卡塔尼亚大学妇产科研究所普通外科和医学外科专业;英国牛津丘吉尔医院,牛津大学医院NHS基金会信托,肝胆胰外科;复旦大学中山医院妇科肿瘤科,上海,中国贡献:(一)构思与设计:M Morotti,T Shi;(II) 行政支持:无;(III) 提供研究材料或患者:无;(IV) 数据收集和汇编:M Morotti,G Valenti;(V) 数据分析与解释:M Morotti,VK Mavroeidis,T Shi;(VI) 手稿写作:所有作者;(VII) 手稿的最终批准:所有作者。这些作者对这项工作做出了同样的贡献。通讯:Matteo Morotti。英国牛津大学纳菲尔德妇女与生殖健康系。电子邮件:drmorottimatteo@gmail.com.
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引用次数: 0
A case report of endomrtrial carcinoma by DA Vinci robotic surgical system DA Vinci机器人手术系统治疗子宫内膜癌1例
Pub Date : 2021-01-01 DOI: 10.21037/GPM-21-2
Ai-ming Lin, Xin-Sheng Lyu, Xiaojie Wang
: Endometrial carcinoma is one of the most common cancers in the female reproductive tract, which affects women’s health seriously. It is of vital important for patients of endometrial carcinoma to undergo surgery treatment, since most patients are in the early stages of the disease when they are first diagnosed with good prognosis. At present, the commonly used surgical methods for endometrial cancer include traditional open surgery, laparoscopic surgery, single-hole endoscopic surgery, and robot surgery system, which brings new hope for the disease treatment. As a new advanced technology, robot-assisted surgery (RAS) has shown a few of advantages over traditional surgery, especially it can not only overcome complex anatomy, low exposure, surgical precision, and fixing lymph node, but also decrease the incidence of postoperative complication. We reported a 52-year-old patient with endometrial carcinoma complained of 2-month history of vaginal bleeding. After undergoing endometrial sampling with hysteroscopy, the patient was diagnosed that the mass was located in the border of cervix and uterus cavity. Successfully, the patient was preoperative diagnosed as endometrial carcinoma (type II, stage II) and accepted radical hysterectomy (type II), omentum resection, pelvic and abdominal para-aortic lymphadenectomy with DA Vinci robotic surgical system. The aim of this video is to describe the use of this kind of surgery, and share our experience of DA Vinci robotic surgical system.
子宫内膜癌是女性生殖道最常见的肿瘤之一,严重影响女性健康。对于子宫内膜癌患者来说,手术治疗是至关重要的,因为大多数患者在首次诊断时处于疾病的早期阶段,预后良好。目前,子宫内膜癌常用的手术方式有传统的开放手术、腹腔镜手术、单孔内镜手术、机器人手术系统等,为该病的治疗带来了新的希望。作为一项新兴的先进技术,机器人辅助手术(robot-assisted surgery, RAS)在克服解剖复杂、低暴露、手术精度、淋巴结固定等优点的同时,也降低了术后并发症的发生率。我们报告一位52岁的子宫内膜癌患者,主诉有2个月的阴道出血史。经宫腔镜子宫内膜取样,诊断肿块位于宫颈与子宫腔交界处。患者术前成功诊断为子宫内膜癌(II型,II期),采用达芬奇机器人手术系统行根治性子宫切除术(II型)、大网膜切除术、盆腔及腹部腹主动脉旁淋巴结切除术。这个视频的目的是描述这种手术的使用,并分享我们的经验达芬奇机器人手术系统。
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引用次数: 0
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Gynecology and pelvic medicine
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