Pub Date : 2022-05-06DOI: 10.1186/s13054-022-04001-4
P. Guerci, Thibaut Belveyre, N. Mongardon, E. Novy
{"title":"When to start vasopressin in septic shock: the strategy we propose","authors":"P. Guerci, Thibaut Belveyre, N. Mongardon, E. Novy","doi":"10.1186/s13054-022-04001-4","DOIUrl":"https://doi.org/10.1186/s13054-022-04001-4","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48966989","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-05DOI: 10.1186/s13054-022-04000-5
E. Waele, Arthur R. H. Zanten
{"title":"Routine use of indirect calorimetry in critically ill patients: pros and cons","authors":"E. Waele, Arthur R. H. Zanten","doi":"10.1186/s13054-022-04000-5","DOIUrl":"https://doi.org/10.1186/s13054-022-04000-5","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":"46 1","pages":"1-4"},"PeriodicalIF":0.0,"publicationDate":"2022-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"65772297","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-05-03DOI: 10.1186/s13054-022-03967-5
Yongfang Zhou, Jie Yang, Bo Wang, Peng Wang, Zhen Wang, Yunqing Yang, Guopeng Liang, Xiaorong jing, Xiao-dong Jin, Zhongwei Zhang, Yi-yun Deng, Chenggong Hu, X. Liao, W. Yin, Zhihong Tang, Yongming Tian, L. Tao, Yan Kang
{"title":"Sequential use of midazolam and dexmedetomidine for long-term sedation may reduce weaning time in selected critically ill, mechanically ventilated patients: a randomized controlled study","authors":"Yongfang Zhou, Jie Yang, Bo Wang, Peng Wang, Zhen Wang, Yunqing Yang, Guopeng Liang, Xiaorong jing, Xiao-dong Jin, Zhongwei Zhang, Yi-yun Deng, Chenggong Hu, X. Liao, W. Yin, Zhihong Tang, Yongming Tian, L. Tao, Yan Kang","doi":"10.1186/s13054-022-03967-5","DOIUrl":"https://doi.org/10.1186/s13054-022-03967-5","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45030148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.1186/s13054-022-03937-x
G. Musso, C. Taliano, Federica Molinaro, Caterina Fonti, Deliana Veliaj, Davide Torti, E. Paschetta, E. Castagna, G. Carbone, L. Laudari, Claudio Aseglio, Edoardo Zocca, Sonia Chioni, Laura Ceretto Giannone, Federica Arabia, Cecilia Deiana, Francesca Maria Benato, Marta Druetta, Giorgio Campagnola, Margherita Borsari, Martina Mucci, Tiziana Rubatto, Mara Peyronel, Gloria Tirabassi
{"title":"Early prolonged prone position in noninvasively ventilated patients with SARS-CoV-2-related moderate-to-severe hypoxemic respiratory failure: clinical outcomes and mechanisms for treatment response in the PRO-NIV study","authors":"G. Musso, C. Taliano, Federica Molinaro, Caterina Fonti, Deliana Veliaj, Davide Torti, E. Paschetta, E. Castagna, G. Carbone, L. Laudari, Claudio Aseglio, Edoardo Zocca, Sonia Chioni, Laura Ceretto Giannone, Federica Arabia, Cecilia Deiana, Francesca Maria Benato, Marta Druetta, Giorgio Campagnola, Margherita Borsari, Martina Mucci, Tiziana Rubatto, Mara Peyronel, Gloria Tirabassi","doi":"10.1186/s13054-022-03937-x","DOIUrl":"https://doi.org/10.1186/s13054-022-03937-x","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44584863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-29DOI: 10.1186/s13054-022-03991-5
P. Honore, S. Redant, Pharan Djimafo, T. Preseau, B. Cismas, K. Kaefer, Leonel Barreto Gutierrez, Sami Anane, R. Attou, A. Gallerani, D. De Bels
{"title":"Membrane adsorption in vancomycin treatment is membrane type dependent in CVVHDF: dose correction is crucial","authors":"P. Honore, S. Redant, Pharan Djimafo, T. Preseau, B. Cismas, K. Kaefer, Leonel Barreto Gutierrez, Sami Anane, R. Attou, A. Gallerani, D. De Bels","doi":"10.1186/s13054-022-03991-5","DOIUrl":"https://doi.org/10.1186/s13054-022-03991-5","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48189069","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-28DOI: 10.1186/s13054-022-03988-0
Lakhmir S Chawla
Preclinical models of acute kidney injury (AKI) consistently demonstrate that a uremic milieu enhances renal recovery and decreases kidney fibrosis. Similarly, significant decreases in monocyte/macrophage infiltration, complement levels, and other markers of inflammation in the injured kidney are observed across multiple studies and species. In essence, decreased renal clearance has the surprising and counterintuitive effect of being an effective treatment for AKI. In this Perspective, the author suggests a hypothesis describing why the uremic milieu is kidney protective and proposes a clinical trial of 'permissive azotemia' to improve renal recovery and long-term renal outcomes in critically ill patients with severe AKI.
急性肾损伤（AKI）的临床前模型一致表明，尿毒症环境可促进肾脏恢复并减少肾脏纤维化。同样，在多项研究和多个物种中都观察到单核细胞/巨噬细胞浸润、补体水平以及损伤肾脏中的其他炎症标志物明显减少。从本质上讲，降低肾脏清除率具有令人惊讶的反直觉效果，是治疗 AKI 的有效方法。在这篇《透视》中，作者提出了一个假设，描述了为什么尿毒症环境对肾脏有保护作用，并建议进行 "允许性氮质血症 "临床试验，以改善严重 AKI 重症患者的肾脏恢复和长期肾脏预后。
{"title":"Permissive azotemia during acute kidney injury enables more rapid renal recovery and less renal fibrosis: a hypothesis and clinical development plan.","authors":"Lakhmir S Chawla","doi":"10.1186/s13054-022-03988-0","DOIUrl":"10.1186/s13054-022-03988-0","url":null,"abstract":"<p><p>Preclinical models of acute kidney injury (AKI) consistently demonstrate that a uremic milieu enhances renal recovery and decreases kidney fibrosis. Similarly, significant decreases in monocyte/macrophage infiltration, complement levels, and other markers of inflammation in the injured kidney are observed across multiple studies and species. In essence, decreased renal clearance has the surprising and counterintuitive effect of being an effective treatment for AKI. In this Perspective, the author suggests a hypothesis describing why the uremic milieu is kidney protective and proposes a clinical trial of 'permissive azotemia' to improve renal recovery and long-term renal outcomes in critically ill patients with severe AKI.</p>","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":"116"},"PeriodicalIF":0.0,"publicationDate":"2022-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047291/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46619375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-21DOI: 10.1186/s13054-022-03972-8
S. Soussi, Divya Sharma, P. Jüni, G. Lebovic, L. Brochard, J. Marshall, P. Lawler, M. Herridge, N. Ferguson, L. Del Sorbo, E. Féliot, A. Mebazaa, Erica Acton, J. Kennedy, Wei Xu, E. Gayat, C. D. dos Santos, Sabri Alexandre Etienne Soussi Mebazaa Gayat, S. Soussi, A. Mebazaa, E. Gayat, Sabri Laurent John C. Margaret Claudia C. Soussi Brochard Marshall Herridge Dos Santos, L. Brochard, J. Marshall, M. Herridge, C. C. Dos Santos
{"title":"Identifying clinical subtypes in sepsis-survivors with different one-year outcomes: a secondary latent class analysis of the FROG-ICU cohort","authors":"S. Soussi, Divya Sharma, P. Jüni, G. Lebovic, L. Brochard, J. Marshall, P. Lawler, M. Herridge, N. Ferguson, L. Del Sorbo, E. Féliot, A. Mebazaa, Erica Acton, J. Kennedy, Wei Xu, E. Gayat, C. D. dos Santos, Sabri Alexandre Etienne Soussi Mebazaa Gayat, S. Soussi, A. Mebazaa, E. Gayat, Sabri Laurent John C. Margaret Claudia C. Soussi Brochard Marshall Herridge Dos Santos, L. Brochard, J. Marshall, M. Herridge, C. C. Dos Santos","doi":"10.1186/s13054-022-03972-8","DOIUrl":"https://doi.org/10.1186/s13054-022-03972-8","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48907260","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-21DOI: 10.1186/s13054-022-03985-3
F. Corradi, F. Guarracino, G. Santori, C. Brusasco, G. Tavazzi, G. Via, S. Mongodi, F. Mojoli, Raffaello Umberto Dario Biagini, A. Isirdi, F. Dazzi, C. Robba, L. Vetrugno, F. Forfori, Maria Lidia Alessandro Laura Francesco Elisa Samuele Alb Bologna Cardu Crocetti Cundari Del Frate Ferrari L, Maria Lidia Bologna, Alessandro Cardu, L. Crocetti, F. Cundari, E. Del Frate, Samuele Ferrari, Alberto Laffi, Elena Marrucci, Marco Monfroni, Chiara Piagnani, Erika Taddei, L. Tecchi, Sara Tempini, Debora Tognarelli, C. Vullo
{"title":"Ultrasound localization of central vein catheter tip by contrast-enhanced transthoracic ultrasonography: a comparison study with trans-esophageal echocardiography","authors":"F. Corradi, F. Guarracino, G. Santori, C. Brusasco, G. Tavazzi, G. Via, S. Mongodi, F. Mojoli, Raffaello Umberto Dario Biagini, A. Isirdi, F. Dazzi, C. Robba, L. Vetrugno, F. Forfori, Maria Lidia Alessandro Laura Francesco Elisa Samuele Alb Bologna Cardu Crocetti Cundari Del Frate Ferrari L, Maria Lidia Bologna, Alessandro Cardu, L. Crocetti, F. Cundari, E. Del Frate, Samuele Ferrari, Alberto Laffi, Elena Marrucci, Marco Monfroni, Chiara Piagnani, Erika Taddei, L. Tecchi, Sara Tempini, Debora Tognarelli, C. Vullo","doi":"10.1186/s13054-022-03985-3","DOIUrl":"https://doi.org/10.1186/s13054-022-03985-3","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48542044","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-19DOI: 10.1186/s13054-022-03986-2
B. Candel, Wouter Raven, H. Lameijer, W. Thijssen, Fabian Temorshuizen, Christiaan E. Boerma, N. D. de Keizer, E. de Jonge, B. de Groot
{"title":"The effect of treatment and clinical course during Emergency Department stay on severity scoring and predicted mortality risk in Intensive Care patients","authors":"B. Candel, Wouter Raven, H. Lameijer, W. Thijssen, Fabian Temorshuizen, Christiaan E. Boerma, N. D. de Keizer, E. de Jonge, B. de Groot","doi":"10.1186/s13054-022-03986-2","DOIUrl":"https://doi.org/10.1186/s13054-022-03986-2","url":null,"abstract":"","PeriodicalId":92888,"journal":{"name":"Critical care (Houten, Netherlands)","volume":" 46","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41252890","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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