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Handbook of behavioral neuroscience最新文献

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Amygdala physiology in pain. 疼痛的杏仁核生理学。
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 Epub Date: 2020-03-31 DOI: 10.1016/b978-0-12-815134-1.00004-0
Volker Neugebauer

The amygdala has emerged as an important brain area for the emotional-affective dimension of pain and pain modulation. The amygdala receives nociceptive information through direct and indirect routes. These excitatory inputs converge on the amygdala output region (central nucleus) and can be modulated by inhibitory elements that are the target of (prefrontal) cortical modulation. For example, inhibitory neurons in the intercalated cell mass in the amygdala project to the central nucleus to serve gating functions, and so do inhibitory (PKCdelta) interneurons within the central nucleus. In pain conditions, synaptic plasticity develops in output neurons because of an excitation-inhibition imbalance and drives pain-like behaviors and pain persistence. Mechanisms of pain related neuroplasticity in the amygdala include classical transmitters, neuropeptides, biogenic amines, and various signaling pathways. An emerging concept is that differences in amygdala activity are associated with phenotypic differences in pain vulnerability and resilience and may be predetermining factors of the complexity and persistence of pain.

杏仁核已经成为疼痛和疼痛调节的情绪-情感维度的重要大脑区域。杏仁核通过直接和间接途径接收伤害性信息。这些兴奋性输入汇聚到杏仁核输出区(中央核)，并可被抑制元件(前额叶)皮质调节的目标所调节。例如，杏仁核嵌入细胞团中的抑制性神经元向中央核投射，发挥门控功能，中央核内的抑制性(PKCdelta)中间神经元也是如此。在疼痛条件下，突触可塑性在输出神经元中发展，因为兴奋-抑制不平衡，驱动疼痛样行为和疼痛持续。杏仁核疼痛相关的神经可塑性机制包括经典递质、神经肽、生物胺和各种信号通路。一个新兴的概念是，杏仁核活动的差异与疼痛易感性和恢复力的表型差异有关，并且可能是疼痛复杂性和持久性的预先决定因素。
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引用次数: 17
Neuronal diversity of the amygdala and the bed nucleus of the stria terminalis. 杏仁核和终纹床核的神经元多样性。
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 Epub Date: 2020-03-31 DOI: 10.1016/b978-0-12-815134-1.00003-9
Anna Beyeler, Joanna Dabrowska
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引用次数: 33
Tryptophan hydroxylase and serotonin synthesis regulation 色氨酸羟化酶与血清素合成调节
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 DOI: 10.1016/S1569-7339(10)70078-3
H. Hasegawa, K. Nakamura
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引用次数: 14
Serotonin and the neurobiology of anxious states 血清素和焦虑状态的神经生物学
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 DOI: 10.1016/S1569-7339(10)70091-6
C. Lowry, M. Hale
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引用次数: 18
The amygdalar opioid system. 杏仁核阿片系统。
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 Epub Date: 2020-03-31 DOI: 10.1016/B978-0-12-815134-1.00008-8
Marlene A Wilson, Alexander J McDonald
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引用次数: 2
5-HT neurons and central CO2 chemoreception 5-HT神经元和中枢CO2化学接受
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 DOI: 10.1016/S1569-7339(10)70085-0
Cardin I. Dohle, G. Richerson
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引用次数: 2
Serotonin and basal sensory–motor control 血清素和基础感觉运动控制
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 DOI: 10.1016/S1569-7339(10)70087-4
R. Carey
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引用次数: 4
Genetic, epigenetic, and environmental factors in serotonin-associated disease condition 血清素相关疾病的遗传、表观遗传和环境因素
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 DOI: 10.1016/S1569-7339(10)70108-9
E. Friedel, A. Heinz
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引用次数: 3
Serotonin and serotonin receptors in hallucinogen action 致幻剂作用中的血清素和血清素受体
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 DOI: 10.1016/S1569-7339(10)70103-X
A. Halberstadt, D. Nichols
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引用次数: 11
Index 指数
Handbook of behavioral neuroscience
Pub Date : 2020-01-01 DOI: 10.1016/b978-0-12-815134-1.09990-6
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引用次数: 0
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