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Left But Not Right Ventricular Abnormal Doppler Waves 左心室多普勒波异常
Pub Date : 2020-06-12 DOI: 10.31487/j.jicoa.2019.04.01
C. Meune, F. Goudot, S. Msadek, T. Boukertouta
The presence of a normal atrial electrical activity together with the absence of mechanical atrial activity hasbeen reported after successful cardioversion and is named atrial stunning. In this observation, we report theexistence of left but not right atrial stunning.
在心脏复律成功后,出现了正常的心房电活动,但没有机械的心房活动,这种现象被称为心房昏迷。在这个观察中,我们报告了左心房昏迷的存在,而不是右心房昏迷。
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引用次数: 0
Efficiency of Connected Health Telemonitoring Platform for Patients with High Blood Pressure 高血压患者联网健康远程监护平台的有效性研究
Pub Date : 2020-06-12 DOI: 10.31487/j.jicoa.2020.03.09
C. Morcillo, José Luis Gálvez Romero
Background: Chronic diseases are expected to double their current incidence in people over 65, before by2030. Cardiovascular diseases, such as ischemic heart disease and heart failure, are the most common causeof morbidity and mortality in developed countries and high blood pressure is the most prevalent risk factor.Telemedicine collects data, shares information and provides clinical care, education, public health andremote administrative services. Telehealth and specially connected health platforms, have the potential toimprove the health care system, reduce costs and increase patient satisfaction.Methods: During 2018, 111 patients with high blood pressure (81 (73%) men and 30 (27%) women withan average age 58,4 years) were selected and followed for 12 months. All patients included in thetelemonitoring program, received the Connected Health application on their smartphone and a bluetoothdevice to measure blood pressure. The application reinforces education about the disease, treatmentcompliance, blood pressure monitoring and in case of decompensation, generates alarms that trigger aresponse by the medical team with video consultation.Results: To analyse the difference in blood pressure (systolic and diastolic), we calculate the average of thefirst (when patients added to the program) and last 30 measurements after the 12-month follow-up. Weobserved a reduction of 5,7 mmHg (4%) in systolic and 4 mmHg (5%) in diastolic blood pressure (p <0.05).The use of the connected health platform avoided 3,2% of costs (Blood Pressure Holter and outpatient visits)in one year. The patient satisfaction analysed with the Net Promoting Score of the services implicatedincreased 2.2 points during the study period.Conclusion: A telemonitoring platform for patients with high blood pressure, based on healtheducation, treatment compliance, blood pressure monitoring and early detection of decompensation,improves blood pressure figures, reduce costs and increase patient satisfaction.
背景:预计到2030年,65岁以上人群的慢性病发病率将翻一番。心血管疾病,如缺血性心脏病和心力衰竭,是发达国家发病率和死亡率最常见的原因,高血压是最普遍的风险因素。远程医疗收集数据,共享信息,并提供临床护理、教育、公共卫生和远程管理服务。远程医疗和专门连接的医疗平台有可能改善医疗保健系统,降低成本,提高患者满意度。方法:在2018年期间,选择111名高血压患者(81名(73%)男性和30名(27%)女性,平均年龄58.4岁),并随访12个月。所有参与监测计划的患者都在智能手机上收到了“互联健康”应用程序和一个测量血压的蓝牙设备。该应用程序加强了有关疾病、治疗依从性、血压监测的教育,在失代偿的情况下,通过视频咨询生成警报,触发医疗团队的反应。结果:为了分析血压(收缩压和舒张压)的差异,我们计算了12个月随访后第一次(当患者加入该程序时)和最后30次测量的平均值。我们观察到收缩压降低了5.7mmHg(4%),舒张压降低了4mmHg(5%)(p<0.05)。使用联网健康平台在一年内避免了3.2%的成本(血压动态心电图和门诊就诊)。在研究期间,用所涉及服务的净提升分数分析的患者满意度增加了2.2分。结论:一个基于健康教育、治疗依从性、血压监测和早期发现失代偿的高血压患者远程监测平台,可以改善血压数据,降低成本,提高患者满意度。
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引用次数: 3
The Effectiveness of applying for Formative Assessment Objective Structured Clinical Examination (OSCE)for Undergraduate Students in Faculty of Medicine King Abdul Aziz University, Jeddah, Kingdom of Saudi Arabia 沙特阿拉伯王国吉达阿卜杜勒阿齐兹国王大学医学院本科生申请形成性评估目标结构化临床检查(OSCE)的有效性
Pub Date : 2020-06-04 DOI: 10.21203/rs.3.rs-32260/v1
R. Allhiani, S. Abdulwahab, S. Alamri
The use of formative and summative assessment for students have been always a concern for medical professionals such as teachers and students especially when students are at graduating level. This can be supported with increasing the effectiveness and comprehensiveness of the students with appropriate clinical training using a defined structure with questionnaire-based system defined in the methodology to support student’s skills using clinical competencies to form perspective. It has been found that with Objective Structured Clinical Examination can be used as the method to assess the adequacy to support clinical skills of medical students following their competence level. This can be used to support a variety of tests to work on underpinning emergency procedures to interpret investigational data to ensure in-depth and breadth coverage of clinical skills following 5th-year medical students.
对学生使用形成性和总结性评估一直是教师和学生等医疗专业人员关注的问题,特别是在学生处于毕业阶段时。这可以通过适当的临床训练来提高学生的有效性和全面性,使用明确的结构和基于问卷的系统来支持学生使用临床能力来形成观点的方法。本研究发现,客观结构化临床测验可作为评价医学生临床技能支持适足性的方法。这可以用于支持各种测试,以支持紧急程序,以解释研究数据,以确保五年级医学生临床技能的深度和广度覆盖。
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引用次数: 1
High Dietary Salt Intake in Pediatric Patients with Type 1 Diabetes Mellitus Not Related to Overweight and Obesity 儿童1型糖尿病患者高盐饮食摄入与超重和肥胖无关
Pub Date : 2020-05-29 DOI: 10.31487/j.jicoa.2020.02.12
A. Zanfardino, P. Marzuillo, L. Sessa, A. S. Rollato, Veronica Testa, M. Gallo, Alessia Piscopo, Francesca Casaburo, S. Curto, Gulsum Ozen, E. M. Giudice, Santino Confetto, D. Iafusco
Aim: People around the world are consuming much more sodium than is physiologically necessary. Anumber of studies suggest that dietary sodium intake is related to weight gain. The aim of our study was toevaluate in a population of children and adolescents with type 1 diabetes mellitus, possible correlationsbetween the urinary sodium excretion (UNa24h), indirect marker of sodium intake, and both duration ofdiabetes and BMI z-score. Moreover, we also evaluated the correlation between UNa24h and duration ofdiabetes according with the presence/absence of overweight/obesity.Research Design and Methods: Children and adolescents aged between 4 and 18 years with type 1 diabeteswere consecutively enrolled from Regional Center for Pediatric Diabetes in Naples. Urinary sodiumconcentrations were tested in three 24 h urine samples of 68 individuals (204 tests).Results: Mean UNa24h was 141.3±68.2 mmol/24h corresponding to 8.1±3.9 gr of NaCl intake. Seventyfive percent of subjects aged between 4 and 6 years, 95% of subjects aged between 7 and 10 years and79.5% of subjects aged between 11 and 18 years consume more salt of the LARN’s advice.Urinary sodium excretion increased in relation to the increase of duration, in years, of diabetes (p=0.0027).No statistically significant relationship is between UNa24h (mmol/24h) and zBMI (p=0.705).Conclusions: This study shows that young patients with type 1 diabetes have high levels of UNa24h. Giventhe close correlation between the UNa24h and salt intake we can conclude that they take more salt with theirdiet. High salt intake is not related to overweight but to diabetes duration.
目的:世界各地的人们摄入的钠远远超过了生理所需。许多研究表明,饮食中的钠摄入量与体重增加有关。本研究的目的是评估患有1型糖尿病的儿童和青少年人群中尿钠排泄(UNa24h),钠摄入量的间接标记物,与糖尿病持续时间和BMI z-score之间的可能相关性。此外,我们还根据是否存在超重/肥胖评估了UNa24h与糖尿病持续时间之间的相关性。研究设计和方法:从那不勒斯儿科糖尿病区域中心连续招募年龄在4至18岁之间的1型糖尿病儿童和青少年。对68例患者的3份24小时尿样(204次)进行尿钠浓度检测。结果:平均UNa24h为141.3±68.2 mmol/24h,对应于8.1±3.9 g NaCl摄入量。75%的4 - 6岁的受试者,95%的7 - 10岁的受试者和79.5%的11 - 18岁的受试者根据LARN的建议摄入了更多的盐。尿钠排泄量增加与糖尿病病程(以年计)的增加有关(p=0.0027)。UNa24h (mmol/24h)与zBMI无统计学意义(p=0.705)。结论:本研究显示年轻1型糖尿病患者UNa24h水平较高。考虑到24小时睡眠和盐摄入量之间的密切关系,我们可以得出结论,他们在饮食中摄入了更多的盐。高盐摄入与超重无关,但与糖尿病持续时间有关。
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引用次数: 0
Covid-19: Who is at Risk and How to Risk Stratify for Poor Outcome? Covid-19:谁有风险以及如何对不良结果进行风险分层?
Pub Date : 2020-05-26 DOI: 10.33140/coa.05.02.07
S. Raza
The SARS-COV-2 is not even 90 days old and much is already known about it by scientists and healthcare professionals across the globe. However, there are still areas of knowledge gap and uncertainty. This has left us with many unanswered questions and members of public in fear and confusion.
SARS-COV-2甚至还不到90天,全球的科学家和医疗保健专业人员已经对它有了很多了解。然而,仍有知识差距和不确定性的领域。这给我们留下了许多悬而未决的问题,也给公众留下了恐惧和困惑。
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引用次数: 0
Transcatheter Closure of Atrial Septal Defect with Amplatzer Device in Adolescence and Adults: Short Term Results: MCVTC Experience 用Amplatzer装置经导管封闭青少年和成人房间隔缺损:短期结果:MCVTC经验
Pub Date : 2020-05-05 DOI: 10.33140/coa.05.02.03
Introduction: Atrial septal defect (ASD) is one of the common congenital heart diseases accounting for 8% to 10% of total congenital heart disease at birth and one of the most common diseases in adulthood. Ostium Secundum (OS) ASD has been successfully closed surgically for over several decades. But even though the results are better, it is associated with discomfort, morbidity, and a thoracotomy scar. Transcatheter closure in these patients has advanced rapidly in recent years and represents a growing field in invasive cardiology. Methods: This prospective study was conducted at Manmohan cardiothoracic vascular and transplant center, Maharajgung, Kathmandu, Nepal. Fifty-two (52) patients with a diagnosis of OS ASD assessed for device closure. Patients underwent transthoracic and trans oesophageal echocardiography for the defect location, size, number, and associated anomalies. All patients with OS ASD fulfilling the inclusion criteria enrolled for device closure. The procedure conducted under fluoroscopy and transesophageal guidance. The cases were followed up at 3 and 6 months, reassessed clinically and by echocardiography for any complications. Results: The patients with ASD who enrolled in this study belonged to the age group of 14 to 63 years. The device closure attempted in 46 patients, and the remaining six patients excluded from the procedure due to unsuitable anatomy after GA guided TEE done. Among 46 patients, 44 (95%) had successful device closure. The mean age of the patient was 35.7+ 10 and 33 (71.7%) female, with 13 (28.3%) males. Conclusions: The transcatheter device closure of ASD in adolescents and adults has a high success rate with fewer complications and found to be safely documented during immediate and short term follow up. However, long terms follow up is required to conclude it.
房间隔缺损(Atrial septal缺损,ASD)是一种常见的先天性心脏病,占出生时先天性心脏病总数的8% ~ 10%,是成年后最常见的疾病之一。在过去的几十年里,ASD已经成功地通过手术关闭了第二口(OS)。但即使效果更好,它也与不适、发病率和开胸疤痕有关。近年来,这些患者的经导管闭合治疗进展迅速,是侵入性心脏病学中一个不断发展的领域。方法:这项前瞻性研究在尼泊尔加德满都Maharajgung的曼莫汉心胸血管和移植中心进行。对52例诊断为OS ASD的患者进行器械关闭评估。患者接受经胸和经食管超声心动图检查缺损的位置、大小、数量和相关异常。所有符合纳入标准的OS ASD患者入组进行器械关闭。该手术在透视和经食管指导下进行。随访3个月和6个月,重新评估临床和超声心动图是否有并发症。结果:本研究纳入的ASD患者年龄在14 ~ 63岁之间。46例患者尝试闭合装置,其余6例患者在GA引导TEE完成后因解剖结构不合适而被排除。46例患者中,44例(95%)成功关闭装置。患者平均年龄35.7+ 10岁,女性33岁(71.7%),男性13岁(28.3%)。结论:经导管装置封堵青少年和成人ASD成功率高,并发症少,经即时和短期随访记录安全。然而,结案需要长期的后续工作。
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引用次数: 0
A Clinical Report on the Relationships Between Metabolism and Obesity, Type 2 Diabetes, Cardiovascular Risk by Using the GH-Method: Math-Physical Medicine 应用gh -方法研究代谢与肥胖、2型糖尿病、心血管风险关系的临床报告:数理医学
Pub Date : 2020-05-05 DOI: 10.33140/coa.05.02.01
Gerald C. Hsu
By using the GH-Method: math-physical medicine and big data on one particular patient (the author), this clinical paper describes the relationship between his metabolic state and medical conditions, including obesity, type 2 diabetes (T2D), and cardiovascular risk.
本临床论文运用GH-Method:数理医学和大数据分析某患者(作者)的代谢状态与肥胖、2型糖尿病(T2D)、心血管风险等疾病之间的关系。
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引用次数: 0
Hepatocellular Carcinoma with Vascular Invasion and Cardiac Metastasis Causing Progressive Liver and Renal Failure: A Case Report and Literature Review 肝细胞癌伴血管侵犯及心脏转移致进行性肝肾功能衰竭1例报告及文献复习
Pub Date : 2020-05-05 DOI: 10.33140/coa.05.02.02
Hepatocellular carcinoma (HCC) is the most common primary tumor of the liver and eighth-most common cancer. The most frequent sites of metastasis are the lungs, the bones, the lymphatics, and the brain. An isolated metastasis of a HCC to the right atrium and inferior vena cava (IVC) is extremely rare. Here we discuss a case of a 61-year-old female who presented with two weeks of generalized weakness and was found to have advanced stage HCC with metastasis to the IVC and right atrium of her heart. We recommend that echocardiography should be routinely performed for all patients with advanced HCC because if metastasis to the right atrium is not detected early enough, the clinical course will be complicated by many unexpected cardiovascular complications that can be fatal. Currently the prognosis for this disease is very poor so further investigation into surgical and medical treatments needs to occur.
肝细胞癌(HCC)是最常见的肝脏原发肿瘤,也是第八大常见癌症。最常见的转移部位是肺、骨、淋巴管和脑。肝细胞癌转移到右心房和下腔静脉(IVC)是非常罕见的。我们在此讨论一个61岁女性的病例,她表现出两周的全身无力,并被发现患有晚期HCC,并转移到下腔静脉和右心房。我们建议对所有晚期HCC患者进行常规超声心动图检查,因为如果转移到右心房没有及早发现,临床过程将会因许多意想不到的心血管并发症而复杂化,这些并发症可能是致命的。目前这种疾病的预后非常差,因此需要进一步研究手术和药物治疗。
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引用次数: 0
Post PCI with stenting Follow-Up in Women for 7 Years in Public Sector Tertiary Care Cardiac Unit. Retrospective Study 公立三级保健心脏科妇女PCI术后支架随访7年。回顾性研究
Pub Date : 2020-05-05 DOI: 10.33140/coa.05.02.05
Introduction: Despite of the fact that there is continual improvement in diagnostic and therapeutic procedures in catherization Lab introduction of better catheter techniques and new-generation stents and with the acquisition of knowledge from largescale clinical trials Still women appear to have a higher in-hospital mortality after PCI with stenting and during long term follow up specially in developing countries of South Asia the, Reason could be multi-factorial in women. The objectives: The goals of treatment in PCI with stenting in Women is to improve quality of life, to prevent CHD from becoming symptomatic, prevent myocardial infarction, cardiac death and heart failure, the approaches to achieve these goals at the societal or individual level in this regards differ among various countries, the data that have been published are often limited due to the relatively small number of western women. It is important to collect data in under developed countries on outcomes of long term follow up of women with AMI after PCI with stenting to change the global perception of treatment of women with myocardial infarction. Material and Method: Out of 3300 patients, underwent successful PCI with stenting during 2010 to 2016 in Cath Lab of cardiology department of Dow University of Health and Sciences Karachi Pakistan , 577 patients with Sciences Karachi Pakistan, 577 patients with Myocardial infarction within 7 days were included in study and they constitute the present followup population. Additional data regarding noncardiac comorbid diseases and Risk factors were obtained along with crucial aspects of women’s health, such as menopausal status, use of hormonal contraceptives, Follow-up was planned after 1 month and then with annualy for 7 years. The primary end point of study were the long-term rate of major adverse cardiac events (i.e. death, Infarction, and repeat revascularization). The secondary end points were the individual components of the major adverse cardiac events and stent thrombosis. Result: This observational study was conducted by reviewing the record of cases performed and getting information on follow up visits of patients for 7 years from June 2010 to June 2016, out of total 3300 procedure 577 patients were included in the study who underwent PCI with stenting with in the 7 day of Myocardial infarction consisting of 346 patient from urban and 237 people from Rural areas of Sindh Balochistan Provinice of Pakistan Revascularization with stenting was performed in 313 patients 40-50 years of age followed by 219 patients 56-70 years of age in comparison to 23 in older group > 70 years and 22 in younger age < 40 years ,In 528 (91.5%)patients PCI with BMS, in 28 (4.8%)patients DES alone and in 21 (3.6%)patients with BMS and DES performed The odds of short-term mortality were significantly higher among older post - menopausal group compared to premenopausal patients <55. I3 patients (5 patients during hospitalization) and 8 patients died withi
导论:尽管导管术的诊断和治疗方法不断改进,实验室引进了更好的导管技术和新一代支架,并从大规模临床试验中获得了知识,但女性在PCI合并支架置入后和长期随访期间的住院死亡率似乎更高,特别是在南亚发展中国家,原因可能是女性的多因素。目的:女性PCI支架治疗的目标是改善生活质量,防止冠心病出现症状,预防心肌梗死、心源性死亡和心力衰竭,在这方面,各国在社会或个人层面实现这些目标的方法不同,由于西方女性人数相对较少,已发表的数据往往有限。在欠发达国家收集关于PCI合并支架植入术后AMI女性患者长期随访结果的数据,以改变全球对女性心肌梗死治疗的看法是很重要的。材料与方法:2010 - 2016年在巴基斯坦卡拉奇陶氏卫生科学大学心内科Cath实验室成功行PCI支架术的3300例患者中,577例巴基斯坦卡拉奇科学大学患者和577例7天内心肌梗死患者纳入研究,构成本研究的随访人群。获得了关于非心脏合并症和风险因素的其他数据,以及妇女健康的关键方面,如更年期状况、激素避孕药的使用情况。计划在1个月后进行随访,然后每年随访7年。研究的主要终点是主要心脏不良事件(即死亡、梗死和重复血运重建术)的长期发生率。次要终点是主要心脏不良事件和支架血栓形成的单个组成部分。结果:本观察性研究通过回顾2010年6月至2016年6月7年的病例记录并获取患者随访信息进行。总3300程序577例接受PCI患者纳入研究与心肌梗塞7天的支架组成的346名患者从237年城市和农村地区的人们信德省巴基斯坦俾路支省Provinice血管再生与支架进行了313例40 - 50岁之后,219名患者56 - 70岁相比,23日在年长组> 70年和22在年轻的年龄< 40年,528年(91.5%)患者PCI BMS,在28例(4.8%)单独使用DES的患者和21例(3.6%)同时使用BMS和DES的患者中,老年绝经后组的短期死亡率明显高于绝经前患者<55。3例患者(住院期间5例),8例患者在PCI术后30天内死亡。随访7年死亡57例(9.8%),共31例(58.5%)死于合并症,其余27例(39.4%)死于心肌梗死。老年患者心律失常5例(9.4%),心衰加重8例(42.1%)。7年随访,靶血管完全闭合,28例(4.8%)行再PCI, 13例(2.2%)行冠脉搭桥。71例(12.3%)患者的主要原因可能是治疗不遵医嘱。
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引用次数: 0
Prevalence and Associated Factors of Hypertension among Assosa town, WesternEthiopia, 2018 2018年尼日利亚西部阿索萨镇高血压患病率及相关因素调查
Pub Date : 2020-05-05 DOI: 10.33140/coa.05.02.06
Lalisa M Gadisa
Background: Hypertension, the global first and third risk for mortality and disease burden respectively, is recording an increment in Sub-Saharan Africa countries. This study aimed to identify prevalence and its associated risk factor of Hypertension in the Assosa town. Objective: To identify prevalence and factors associated with hypertension in the study area to increase it’s prevention and control methods. Methods & materials: Institutional based cross sectional study design with quota non-probability sampling technique was conducted among patients visited OPD units ofAssosa General Hospital (AGH) andAssosa Health Center(AHC) fromMarch to June 2018. All outpatients were included. To collect data, pre-tested structured questionnaire and face to face interviews were used. Components ofstatisticalresearch software SPSS version-21 like frequency table, chi-square test of independence & logistic regression was used to enter, analyze, summarize and characterize disease and associated factors data. Result: The study was conducted among 194 participants(152 from AGH and 42 from AHC) with 102 males and 92 females. Prevalence of hypertension among patients visited outpatient units of Assosa General Hospital and Assosa Health Center was 17.5%, and was slightly highest in male than female. Associated factors for hypertension among patients visited OPD units of AGH & AHC were history of hypertension in the family (CI=95% and COR=4.497(1.133-17.844) and being private employee (CI=95% and COR=0.0017(0.001-0.407). Conclusion & recommendation: Prevalence of HTN in the Assosa town, was low and influenced by some risk factors like work status and previousfamily history of hypertension. Even if usual usage ofsalt and using vegetable oil was not associated factor, being private employee were independent factor of HTN. In-depth study is recommended for further investigation. To increase preventative methods of HTN, health education supported by mass media, illustrative posters and anotherstrategies at every government & non government work sector are recommended.
背景:高血压分别是全球死亡和疾病负担的第一和第三大风险,在撒哈拉以南非洲国家呈上升趋势。本研究旨在了解阿索萨镇高血压患病率及其相关危险因素。目的:了解研究区高血压患病率及相关因素,提高高血压防治措施。方法与材料:采用基于机构的横断面研究设计,采用配额非概率抽样技术,对2018年3 - 6月在阿索萨总医院(AGH)和阿索萨健康中心(AHC)门诊就诊的患者进行研究。所有门诊患者均纳入。为了收集数据,采用了预先测试的结构化问卷和面对面访谈。采用SPSS version-21等统计研究软件的组成部分,如频率表、卡方独立性检验和logistic回归,对疾病及相关因素数据进行输入、分析、总结和表征。结果:194名参与者(AGH 152人,AHC 42人),其中男性102人,女性92人。阿索萨总医院和阿索萨保健中心门诊患者高血压患病率为17.5%,男性略高于女性。在AGH和AHC门诊就诊的患者中,高血压的相关因素是家族史(CI=95%, COR=4.497(1.133-17.844))和私企员工(CI=95%, COR=0.0017(0.001-0.407)。结论与建议:阿索萨镇HTN患病率较低,受工作状况和既往高血压家族史等危险因素的影响。即使经常使用食盐和使用植物油不是影响HTN的相关因素,但私营雇员是HTN的独立因素。建议进一步深入研究。为增加HTN的预防方法,建议在各个政府和非政府工作部门开展大众媒体支持的健康教育、说明性海报和其他策略。
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引用次数: 1
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Journal of integrative cardiology open access
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