Pub Date : 1980-12-13DOI: 10.1136/bmj.281.6255.1601
O Ylikorkala, L Viinikka
Histological appearances of well-differentiated papillary carcinoma of
{"title":"Thromboxane A2 in pregnancy and puerperium.","authors":"O Ylikorkala, L Viinikka","doi":"10.1136/bmj.281.6255.1601","DOIUrl":"https://doi.org/10.1136/bmj.281.6255.1601","url":null,"abstract":"Histological appearances of well-differentiated papillary carcinoma of","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1601-2"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.281.6255.1601","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18459501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-12-13DOI: 10.1136/bmj.281.6255.1608
V E Griffith
{"title":"Observations on patients dysphasic after stroke.","authors":"V E Griffith","doi":"10.1136/bmj.281.6255.1608","DOIUrl":"https://doi.org/10.1136/bmj.281.6255.1608","url":null,"abstract":"","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1608-9"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.281.6255.1608","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18459507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-12-13DOI: 10.1136/bmj.281.6255.1640-b
A M Smith
{"title":"Intrinsic hazard of breech presentation.","authors":"A M Smith","doi":"10.1136/bmj.281.6255.1640-b","DOIUrl":"https://doi.org/10.1136/bmj.281.6255.1640-b","url":null,"abstract":"","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1640"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.281.6255.1640-b","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18459523","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-12-13DOI: 10.1136/bmj.281.6255.1642
P A Allen, R T Taylor
{"title":"Fenclofenac and thyroid function tests.","authors":"P A Allen, R T Taylor","doi":"10.1136/bmj.281.6255.1642","DOIUrl":"https://doi.org/10.1136/bmj.281.6255.1642","url":null,"abstract":"","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1642"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.281.6255.1642","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18456703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-12-13DOI: 10.1136/bmj.281.6255.1612
D G Altman
Before tackling some of the trickier issues it is worth making the general point that the sensible interpretation of statistical analysis cannot be independent of the knowledge of what the data are (and how they were obtained). Table I, for example, shows the results of the comparison of two groups of subjects given different treatments with the outcome for each subject recorded as positive or negative. A
{"title":"Statistics and ethics in medical research. VII--Interpreting results.","authors":"D G Altman","doi":"10.1136/bmj.281.6255.1612","DOIUrl":"https://doi.org/10.1136/bmj.281.6255.1612","url":null,"abstract":"Before tackling some of the trickier issues it is worth making the general point that the sensible interpretation of statistical analysis cannot be independent of the knowledge of what the data are (and how they were obtained). Table I, for example, shows the results of the comparison of two groups of subjects given different treatments with the outcome for each subject recorded as positive or negative. A","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1612-4"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.281.6255.1612","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18459508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Immunisation against hepatitis B.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1585-6"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1715065/pdf/brmedj00051-0003.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18458686","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-12-13DOI: 10.1136/bmj.281.6255.1621
P J Evans, J W Lloyd, K M Peet
Modern cases of ergot poisoning (St Anthony's fire) are frequently iatrogenic, and occur when ergot alkaloids are taken in excess. The principal feature is intense vasoconstriction, but sensory neurological disturbances such as paraesthesiae or causalgic-like pains are often described.1 We report on a woman who developed such an autonomic dysaesthesia affecting the lower limbs, which was initially mistaken for a development of her pre-existing chronic back pain.
{"title":"Autonomic dysaesthesia due to ergot toxicity.","authors":"P J Evans, J W Lloyd, K M Peet","doi":"10.1136/bmj.281.6255.1621","DOIUrl":"https://doi.org/10.1136/bmj.281.6255.1621","url":null,"abstract":"Modern cases of ergot poisoning (St Anthony's fire) are frequently iatrogenic, and occur when ergot alkaloids are taken in excess. The principal feature is intense vasoconstriction, but sensory neurological disturbances such as paraesthesiae or causalgic-like pains are often described.1 We report on a woman who developed such an autonomic dysaesthesia affecting the lower limbs, which was initially mistaken for a development of her pre-existing chronic back pain.","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1621"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.281.6255.1621","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18459512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-12-13DOI: 10.1136/bmj.281.6255.1636-d
E Walker
pregnancy. It would, however, be most inappropriate in the context of a sudden increase in blood pressure in the third trimester, particularly if the patient was pregnant for the first time. The reason for this does not lie in the inherent danger of this modest elevation in the blood pressure but the warning it gives of possible impending severe pre-eclampsia. The possibility that this dangerous condition may develop very rapidly justifies a policy of admission in predisposed patients. The alternative policy of outpatient management is only permissible in the case of very reliable patients who have been taught to use Albustix daily. It is stated that diuretics "do not improve the prognosis of hypertension in pregnancy." While this is certainly true, it should be remembered that treatment with methyldopa itself has little or no influence on fetal prognosis.' The most important reason for withholding diuretic treatment in pre-eclampsia is that it may aggravate the hypovolaemia which is characteristic of this condition.2 The first agent mentioned for the parenteral treatment of acutely raised blood pressure is diazoxide. While small doses of this substance have been used without ill effect, the first line of treatment in most hospitals is parenteral hydrallazine.3 Inadequate response to this well-tried agent is extremely rare and, furthermore, it does not have the antidiuretic and tocolytic effects of diazoxide. Infusions of labetolol were recommended and I have found this agent to be safe and effective in lowering acute elevations of blood pressure in pregnancy. The literature contains no reference to its use in obstetrics, though this may well become the drug of first choice in fulminating pre-eclampsia, as it combines considerable potency with more gradual hypotensive effect. This is less likely to jeopardise uteroplacental blood flow. I agree with the authors' statement that longterm use of beta-blockers in pregnancy is controversial.4 However, many authors have failed to confirm reports of an increased perinatal mortality and one author has found an improvement in fetal outcome when oxprenolol was used for hypertension in pregnancy.5
{"title":"Protection against pertussis by immunisation.","authors":"E Walker","doi":"10.1136/bmj.281.6255.1636-d","DOIUrl":"https://doi.org/10.1136/bmj.281.6255.1636-d","url":null,"abstract":"pregnancy. It would, however, be most inappropriate in the context of a sudden increase in blood pressure in the third trimester, particularly if the patient was pregnant for the first time. The reason for this does not lie in the inherent danger of this modest elevation in the blood pressure but the warning it gives of possible impending severe pre-eclampsia. The possibility that this dangerous condition may develop very rapidly justifies a policy of admission in predisposed patients. The alternative policy of outpatient management is only permissible in the case of very reliable patients who have been taught to use Albustix daily. It is stated that diuretics \"do not improve the prognosis of hypertension in pregnancy.\" While this is certainly true, it should be remembered that treatment with methyldopa itself has little or no influence on fetal prognosis.' The most important reason for withholding diuretic treatment in pre-eclampsia is that it may aggravate the hypovolaemia which is characteristic of this condition.2 The first agent mentioned for the parenteral treatment of acutely raised blood pressure is diazoxide. While small doses of this substance have been used without ill effect, the first line of treatment in most hospitals is parenteral hydrallazine.3 Inadequate response to this well-tried agent is extremely rare and, furthermore, it does not have the antidiuretic and tocolytic effects of diazoxide. Infusions of labetolol were recommended and I have found this agent to be safe and effective in lowering acute elevations of blood pressure in pregnancy. The literature contains no reference to its use in obstetrics, though this may well become the drug of first choice in fulminating pre-eclampsia, as it combines considerable potency with more gradual hypotensive effect. This is less likely to jeopardise uteroplacental blood flow. I agree with the authors' statement that longterm use of beta-blockers in pregnancy is controversial.4 However, many authors have failed to confirm reports of an increased perinatal mortality and one author has found an improvement in fetal outcome when oxprenolol was used for hypertension in pregnancy.5","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1636-7"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.281.6255.1636-d","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18459513","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Toxic shock and tampons.","authors":"","doi":"","DOIUrl":"","url":null,"abstract":"","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1639"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1715136/pdf/brmedj00051-0059b.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18459521","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1980-12-13DOI: 10.1136/bmj.281.6255.1602
A J Watson, E Lawlor, J A Keogh
{"title":"Acute folate deficiency during peritoneal dialysis.","authors":"A J Watson, E Lawlor, J A Keogh","doi":"10.1136/bmj.281.6255.1602","DOIUrl":"https://doi.org/10.1136/bmj.281.6255.1602","url":null,"abstract":"","PeriodicalId":9321,"journal":{"name":"British Medical Journal","volume":"281 6255","pages":"1602"},"PeriodicalIF":0.0,"publicationDate":"1980-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1136/bmj.281.6255.1602","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"18459502","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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