Toxoplasma gondii (T. gondii) is considered as one of the highly resistant intracellular parasite mainly found in the central nervous system (CNS), however, it can persist in multiple tissues in the body. Moreover, T. gondii is causing disseminated infections among patients with autoimmune diseases. Thus, the aim of this study was to evaluate the seroprevalence of toxoplasmosis in autoimmune disease Saudi patients. Ninety patients suffer from different autoimmune diseases and forty five healthy controls were subjected to determination of anti T. gondii immunoglobulin G (IgG) antibody seropositivity using commercially available Enzyme-linked Immuno sorbent assay kits (ELISA). The results showed that the seropositivity rate of anti T. gondii IgG antibodies was 22.2% the results are statistically significant. These statistically significant results support the association between T. gondii infection and different autoimmune diseases and suggest the usefulness of performing serological test for detection of infection by toxoplasma, so it is recommended early detection of Toxoplasma in autoimmune diseases patients to prevent any complications.
弓形虫(Toxoplasma gondii, T. gondii)被认为是一种主要存在于中枢神经系统(CNS)的高耐药性细胞内寄生虫，但它可以在体内多个组织中持续存在。此外，弓形虫在自身免疫性疾病患者中引起播散性感染。因此，本研究的目的是评估自身免疫性疾病沙特患者血清弓形虫病的患病率。采用市售酶联免疫吸附测定试剂盒(ELISA)检测90例不同自身免疫性疾病患者和45例健康对照者的抗弓形虫免疫球蛋白G (IgG)抗体血清阳性。结果显示，抗弓形虫IgG抗体血清阳性率为22.2%，结果有统计学意义。这些具有统计学意义的结果支持弓形虫感染与不同自身免疫性疾病之间的关联，并提示进行弓形虫感染的血清学检测是有用的，因此建议自身免疫性疾病患者早期检测弓形虫，以防止任何并发症。
{"title":"Seroprevalence of Toxoplasma Gondii in Saudi Autoimmune Disease Patients","authors":"Khadiga Ahmed Ismail","doi":"10.23880/aii-16000102","DOIUrl":"https://doi.org/10.23880/aii-16000102","url":null,"abstract":"Toxoplasma gondii (T. gondii) is considered as one of the highly resistant intracellular parasite mainly found in the central nervous system (CNS), however, it can persist in multiple tissues in the body. Moreover, T. gondii is causing disseminated infections among patients with autoimmune diseases. Thus, the aim of this study was to evaluate the seroprevalence of toxoplasmosis in autoimmune disease Saudi patients. Ninety patients suffer from different autoimmune diseases and forty five healthy controls were subjected to determination of anti T. gondii immunoglobulin G (IgG) antibody seropositivity using commercially available Enzyme-linked Immuno sorbent assay kits (ELISA). The results showed that the seropositivity rate of anti T. gondii IgG antibodies was 22.2% the results are statistically significant. These statistically significant results support the association between T. gondii infection and different autoimmune diseases and suggest the usefulness of performing serological test for detection of infection by toxoplasma, so it is recommended early detection of Toxoplasma in autoimmune diseases patients to prevent any complications.","PeriodicalId":93259,"journal":{"name":"Annals of immunology & immunotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68917201","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Is there any Relationship between Body Weight and Urine Ketones?","authors":"Hafiz Shahid Hussain","doi":"10.23880/aii-16000108","DOIUrl":"https://doi.org/10.23880/aii-16000108","url":null,"abstract":"","PeriodicalId":93259,"journal":{"name":"Annals of immunology & immunotherapy","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68917263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：