Pub Date : 2021-01-01DOI: 10.29011/2577-1515.100177
{"title":"Controlling the Spread of SARS-CoV-2 by Broadening the Diagnostic Strategy","authors":"","doi":"10.29011/2577-1515.100177","DOIUrl":"https://doi.org/10.29011/2577-1515.100177","url":null,"abstract":"","PeriodicalId":93299,"journal":{"name":"Infectious diseases diagnosis & treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69472287","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-01-01DOI: 10.29011/2577-1515.100172
{"title":"The Prevalence of Human Cystic Echinococcosis in Campania Region: Result of a Regional Screening Project","authors":"","doi":"10.29011/2577-1515.100172","DOIUrl":"https://doi.org/10.29011/2577-1515.100172","url":null,"abstract":"","PeriodicalId":93299,"journal":{"name":"Infectious diseases diagnosis & treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69472181","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.29011/2577-1515.100151
{"title":"Prevention and Control Strategies for Children During COVID-19 Epidemic","authors":"","doi":"10.29011/2577-1515.100151","DOIUrl":"https://doi.org/10.29011/2577-1515.100151","url":null,"abstract":"","PeriodicalId":93299,"journal":{"name":"Infectious diseases diagnosis & treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69472352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2020-01-01DOI: 10.29011/2577-1515.100164
{"title":"SARS-CoV-2 Antigen Testing Program (COVID-ATP): A longitudinal study in 14 UK cancer centers","authors":"","doi":"10.29011/2577-1515.100164","DOIUrl":"https://doi.org/10.29011/2577-1515.100164","url":null,"abstract":"","PeriodicalId":93299,"journal":{"name":"Infectious diseases diagnosis & treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"69472400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The 2014-2016 Ebola epidemic in Guinea highlighted the need for more extensive evaluation of laboratories diagnostic capacities and preparedness in anticipation of future emerging viral disease outbreaks. We developed a questionnaire to assess the diagnostic capacities and preparedness of the four major medical laboratories in Guinea and Mali that are responsible for the provision of Ebola, Lassa, and Dengue diagnostics. The questionnaire inquired about the current state and need for equipment and reagents and adequacy of equipment and training received. In Guinea, all three diagnostic laboratories have the capacity and are well-prepared to perform Ebola diagnostics, however, only two have the capacity and trained staff to diagnose Lassa and none are currently prepared to diagnose Dengue infection. In Mali, the University Clinical Research Center (UCRC) laboratory, which was in charge of Ebola diagnostics during the last epidemic, currently has the capacity and is prepared to diagnose Ebola, Lassa, and Dengue infections. Combined, Guinea and Mali appear to have complementary capacity and preparedness to diagnose these Category A Priority Pathogens. While, the equipment, reagents and training efforts should be maintained, the gap in Dengue diagnostic capability in Guinea should be addressed with further equipping and training of additional district laboratories to strengthen the public health response for all viral diseases in these high-risk, yet, low-resource settings.
{"title":"Diagnostic Laboratories' Capacities and Preparedness for Emerging Viral Diseases in Guinea and Mali.","authors":"Tiffany Zhang Teng, Abdoul Habib Beavogui, Bassirou Diarra, Alexandre Delamou, Jane Holl, Almoustapha Issiaka Maiga, Yeya Dit Sadio Sarro, Amadou Kone, Bourahima Kone, Djeneba Bocar Fofana, Etienne Dembele, Mamadou Saliou Sow, Moussa Seydi, Aboubacar Alassane Oumar, Mahamadou Diakité, Souleymane Diallo, Seydou Doumbia, Sounkalo Dao, Robert L Murphy, Mamoudou Maiga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>The 2014-2016 Ebola epidemic in Guinea highlighted the need for more extensive evaluation of laboratories diagnostic capacities and preparedness in anticipation of future emerging viral disease outbreaks. We developed a questionnaire to assess the diagnostic capacities and preparedness of the four major medical laboratories in Guinea and Mali that are responsible for the provision of Ebola, Lassa, and Dengue diagnostics. The questionnaire inquired about the current state and need for equipment and reagents and adequacy of equipment and training received. In Guinea, all three diagnostic laboratories have the capacity and are well-prepared to perform Ebola diagnostics, however, only two have the capacity and trained staff to diagnose Lassa and none are currently prepared to diagnose Dengue infection. In Mali, the University Clinical Research Center (UCRC) laboratory, which was in charge of Ebola diagnostics during the last epidemic, currently has the capacity and is prepared to diagnose Ebola, Lassa, and Dengue infections. Combined, Guinea and Mali appear to have complementary capacity and preparedness to diagnose these Category A Priority Pathogens. While, the equipment, reagents and training efforts should be maintained, the gap in Dengue diagnostic capability in Guinea should be addressed with further equipping and training of additional district laboratories to strengthen the public health response for all viral diseases in these high-risk, yet, low-resource settings.</p>","PeriodicalId":93299,"journal":{"name":"Infectious diseases diagnosis & treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2020-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8442766/pdf/nihms-1585957.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39424626","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bourahima Kone, Yeya S Sarro, Bocar Baya, Djeneba Dabitao, Nadie Coulibaly, Mamadou Wague, Bassirou Diarra, Oumar Guindo, Moumine Sanogo, Antieme Cg Togo, Amadou Kone, Drissa Goita, Seydou Diabate, Ousmane Kodio, Michael Belson, Sounkalo Dao, Susan Orsega, Robert L Murphy, Souleymane Diallo, Seydou Doumbia, Sophia Siddiqui, Mamoudou Maiga
Diagnosis of HIV infections in resource-limited countries like Mali is based on Rapid Diagnostic Tests (RDTs). The RDTs are diagnostic assays designed for use at the Point-Of-Care (POC), which is quick, cost-effective and easy to perform. However, in these countries, the tests are commonly used without any initial evaluation or monitoring of their performance despite high levels of HIV strain diversity and rapid evolution of the virus. In this study, the reliability and accuracy of HIV RDTs (Determine™, Multispot™, SD Bioline™) used in Mali, where HIV-1 and HIV-2 co-exist, were evaluated from August 2004 to November 2017. A total of 1303 samples from new HIV-suspect patients in Bamako were tested for HIV-1 and HIV-2 using the RDT Determine™, followed by ELISA and Western Blot (WB). The Determine™ test showed a robust diagnostic sensitivity of 98.7% [CI 95: 97.59-99.37] and a diagnostic specificity of 99.2% [CI 95: 98.22-99.67]. The Multispot™ assay showed a diagnostic sensitivity of 98.77% [CI 95: 97.59-99.37] and a diagnostic specificity of 99.2% [CI 95: 98.22-99.67]. The diagnostic sensitivity and specificity of SD Bioline™ HIV-1/2 were 100% [CI 95:72.25-100] and 88.89% [CI 95: 56.50- 98.71], respectively. These data indicate excellent performance for HIV RDTs in Mali and we recommend the use of Determine™ HIV-1/2 for HIV screening and Multispot™ for discriminating HIV-2 from HIV-1 infections.
{"title":"Diagnostic Performances of Three Rapid Diagnostic Tests for Detecting HIV Infections in Mali.","authors":"Bourahima Kone, Yeya S Sarro, Bocar Baya, Djeneba Dabitao, Nadie Coulibaly, Mamadou Wague, Bassirou Diarra, Oumar Guindo, Moumine Sanogo, Antieme Cg Togo, Amadou Kone, Drissa Goita, Seydou Diabate, Ousmane Kodio, Michael Belson, Sounkalo Dao, Susan Orsega, Robert L Murphy, Souleymane Diallo, Seydou Doumbia, Sophia Siddiqui, Mamoudou Maiga","doi":"","DOIUrl":"","url":null,"abstract":"<p><p>Diagnosis of HIV infections in resource-limited countries like Mali is based on Rapid Diagnostic Tests (RDTs). The RDTs are diagnostic assays designed for use at the Point-Of-Care (POC), which is quick, cost-effective and easy to perform. However, in these countries, the tests are commonly used without any initial evaluation or monitoring of their performance despite high levels of HIV strain diversity and rapid evolution of the virus. In this study, the reliability and accuracy of HIV RDTs (Determine<sup>™</sup>, Multispot<sup>™</sup>, SD Bioline<sup>™</sup>) used in Mali, where HIV-1 and HIV-2 co-exist, were evaluated from August 2004 to November 2017. A total of 1303 samples from new HIV-suspect patients in Bamako were tested for HIV-1 and HIV-2 using the RDT Determine<sup>™</sup>, followed by ELISA and Western Blot (WB). The Determine<sup>™</sup> test showed a robust diagnostic sensitivity of 98.7% [CI 95: 97.59-99.37] and a diagnostic specificity of 99.2% [CI 95: 98.22-99.67]. The Multispot<sup>™</sup> assay showed a diagnostic sensitivity of 98.77% [CI 95: 97.59-99.37] and a diagnostic specificity of 99.2% [CI 95: 98.22-99.67]. The diagnostic sensitivity and specificity of SD Bioline<sup>™</sup> HIV-1/2 were 100% [CI 95:72.25-100] and 88.89% [CI 95: 56.50- 98.71], respectively. These data indicate excellent performance for HIV RDTs in Mali and we recommend the use of Determine<sup>™</sup> HIV-1/2 for HIV screening and Multispot™ for discriminating HIV-2 from HIV-1 infections.</p>","PeriodicalId":93299,"journal":{"name":"Infectious diseases diagnosis & treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8336946/pdf/nihms-1565194.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39281320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-09-25DOI: 10.29011/2577-1515.100027
Ferdinando F Andrade, C. Pina-Vaz, A. Rodrigues
Since the 1940s, antimicrobial drugs have substantially reduced morbidity and mortality associated with infectious diseases. The widespread availability of effective antimicrobials has enabled advancements in modern medical and veterinary practice that would have been unachievable without them. Antimicrobial drugs are a precious resource used every day all over the world to effectively treat infections in humans and animals.
{"title":"Antimicrobial Resistance: A One Health Concept Perspective Analysis","authors":"Ferdinando F Andrade, C. Pina-Vaz, A. Rodrigues","doi":"10.29011/2577-1515.100027","DOIUrl":"https://doi.org/10.29011/2577-1515.100027","url":null,"abstract":"Since the 1940s, antimicrobial drugs have substantially reduced morbidity and mortality associated with infectious diseases. The widespread availability of effective antimicrobials has enabled advancements in modern medical and veterinary practice that would have been unachievable without them. Antimicrobial drugs are a precious resource used every day all over the world to effectively treat infections in humans and animals.","PeriodicalId":93299,"journal":{"name":"Infectious diseases diagnosis & treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41347274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-06-18DOI: 10.29011/2577-1515.100023
M. Shah.
Objective: The objective of the study was to assess tuberculosis awareness among nurses. Methodology: A descriptive cross-sectional study was conducted in tertiary care hospital Peshawar KPK. Participants were selected through random sampling technique. The data was collected through a self-developed structured questionnaire. The confidentiality and anonymity was maintained throughout the study. Result: The study consisted of 52 participants including 12(23.1%) males and 40(76.9%) females. Awareness of staff was calculated; result showed that 23.1% had high, 65.4% had moderate and 11.5% had low level of knowledge. Chi square test was applied to check the association between variables and awareness. There was no association found in the result. Conclusion: The study was conducted to assess the tuberculosis awareness among nurses in private tertiary care hospital. The majority of the participant ie 65.4% had moderate level of knowledge. General lack of knowledge was assessed regarding various aspects. Nurses need further training regarding TB.
{"title":"Tuberculosis Awareness Among Nurses Working in Tertiary Care Hospital Peshawar","authors":"M. Shah.","doi":"10.29011/2577-1515.100023","DOIUrl":"https://doi.org/10.29011/2577-1515.100023","url":null,"abstract":"Objective: The objective of the study was to assess tuberculosis awareness among nurses. Methodology: A descriptive cross-sectional study was conducted in tertiary care hospital Peshawar KPK. Participants were selected through random sampling technique. The data was collected through a self-developed structured questionnaire. The confidentiality and anonymity was maintained throughout the study. Result: The study consisted of 52 participants including 12(23.1%) males and 40(76.9%) females. Awareness of staff was calculated; result showed that 23.1% had high, 65.4% had moderate and 11.5% had low level of knowledge. Chi square test was applied to check the association between variables and awareness. There was no association found in the result. Conclusion: The study was conducted to assess the tuberculosis awareness among nurses in private tertiary care hospital. The majority of the participant ie 65.4% had moderate level of knowledge. General lack of knowledge was assessed regarding various aspects. Nurses need further training regarding TB.","PeriodicalId":93299,"journal":{"name":"Infectious diseases diagnosis & treatment","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47805233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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