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PancreaSys: An Automated Cloud-Based Pancreatic Cancer Grading System 胰:基于云的胰腺癌自动分级系统
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2022-02-11 DOI: 10.3389/frsip.2022.833640
Muhammad Nurmahir Mohamad Sehmi, M. F. A. Fauzi, Wan Siti Halimatul Munirah Wan Ahmad, E. Chan
Pancreatic cancer is one of the deadliest diseases which has taken millions of lives over the past 20 years. Due to challenges in grading pancreatic cancer, this study presents an automated cloud-based system, utilizing a convolutional neural network deep learning (DL) approach to classifying four classes of pancreatic cancer grade from pathology image into Normal, Grade I, Grade II, and Grade III. This cloud-based system, named PancreaSys, takes an input of high power field images from the web user interface, slices them into smaller patches, makes predictions, and stitches back the patches before returning the final result to the pathologist. Anvil and Google Colab are used as the backbone of the system to build a web user interface for deploying the DL model in the classification of the cancer grade. This work employs the transfer learning approach on a pre-trained DenseNet201 model with data augmentation to alleviate the small dataset’s challenges. A 5-fold cross-validation (CV) was employed to ensure all samples in a dataset were used to evaluate and mitigate selection bias during splitting the dataset into 80% training and 20% validation sets. The experiments were done on three different datasets (May Grunwald-Giemsa (MGG), hematoxylin and eosin (H&E), and a mixture of both, called the Mixed dataset) to observe the model performance on two different pathology stains (MGG and H&E). Promising performances are reported in predicting the pancreatic cancer grade from pathology images, with a mean f1-score of 0.88, 0.96, and 0.89 for the MGG, H&E, and Mixed datasets, respectively. The outcome from this research is expected to serve as a prognosis system for the pathologist in providing accurate grading for pancreatic cancer in pathological images.
胰腺癌是最致命的疾病之一,在过去的20年里夺走了数百万人的生命。由于胰腺癌分级面临的挑战,本研究提出了一种基于云的自动化系统,利用卷积神经网络深度学习(DL)方法将病理图像中的四类胰腺癌分级分为正常、I级、II级和III级。这个基于云的系统被命名为胰腺系统,它从网络用户界面输入高倍场图像,将它们切成小块,做出预测,在将最终结果返回给病理学家之前将这些小块缝合起来。Anvil和Google Colab作为系统的骨干,构建一个web用户界面,用于部署深度学习模型在癌症等级分类中。本研究采用迁移学习方法对预训练的DenseNet201模型进行数据增强,以减轻小数据集的挑战。在将数据集分成80%的训练集和20%的验证集时,采用5倍交叉验证(CV)来确保使用数据集中的所有样本来评估和减轻选择偏差。实验在三个不同的数据集(May Grunwald-Giemsa (MGG),苏木精和伊红(H&E),以及两者的混合物,称为混合数据集)上进行,以观察模型在两种不同病理染色(MGG和H&E)上的性能。据报道,在从病理图像预测胰腺癌分级方面表现良好,MGG、H&E和Mixed数据集的平均f1评分分别为0.88、0.96和0.89。本研究的结果有望作为病理学家的预后系统,为胰腺癌的病理图像提供准确的分级。
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引用次数: 0
Low Dose CT Denoising by ResNet With Fused Attention Modules and Integrated Loss Functions 融合注意模块和综合损失函数的ResNet低剂量CT去噪
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2022-02-07 DOI: 10.3389/frsip.2021.812193
Luella Marcos, J. Alirezaie, P. Babyn
X-ray computed tomography (CT) is a non-invasive medical diagnostic tool that has raised public concerns due to the associated health risks of radiation dose to patients. Reducing the radiation dose leads to noise artifacts, making the low-dose CT images unreliable for diagnosis. Hence, low-dose CT (LDCT) image reconstruction techniques have offered a new research area. In this study, a deep neural network is proposed, specifically a residual network (ResNet) using dilated convolution, batch normalization, and rectified linear unit (ReLU) layers with fused spatial- and channel-attention modules to enhance the quality of LDCT images. The network is optimized using the integration of per-pixel loss, perceptual loss via VGG16-net, and dissimilarity index loss. Through an ablation experiment, these functions show that they could effectively prevent edge oversmoothing, improve image texture, and preserve the structural details. Finally, comparative experiments showed that the qualitative and quantitative results of the proposed network outperform state-of-the-art denoising models such as block-matching 3D filtering (BM3D), Markovian-based patch generative adversarial network (patch-GAN), and dilated residual network with edge detection (DRL-E-MP).
x射线计算机断层扫描(CT)是一种非侵入性医疗诊断工具,由于辐射剂量对患者的相关健康风险,引起了公众的关注。降低辐射剂量会导致噪声伪影,使低剂量CT图像对诊断不可靠。因此,低剂量CT (LDCT)图像重建技术提供了一个新的研究领域。在本研究中,提出了一种深度神经网络,特别是残差网络(ResNet),该网络使用扩展卷积、批归一化和校正线性单元(ReLU)层,融合了空间和通道关注模块,以提高LDCT图像的质量。该网络使用逐像素损失、通过VGG16-net的感知损失和不相似指数损失的集成进行优化。通过烧蚀实验表明,这些功能可以有效地防止边缘过平滑,改善图像纹理,并保留结构细节。最后,对比实验表明,该网络的定性和定量结果优于最先进的去噪模型,如块匹配3D滤波(BM3D)、基于马尔可夫的补丁生成对抗网络(patch- gan)和带边缘检测的扩展残差网络(DRL-E-MP)。
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引用次数: 0
Analysis of a 2D Representation for CPS Anomaly Detection in a Context-Based Security Framework 基于上下文的安全框架中CPS异常检测的二维表示分析
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2022-01-21 DOI: 10.3389/frsip.2021.814129
Sara Baldoni, M. Carli, F. Battisti
In this contribution, a flexible context-based security framework is proposed by exploring two types of context: distributed and local. While the former consists in processing information from a set of spatially distributed sources, the second accounts for the local environment surrounding the monitored system. The joint processing of these two types of information allows the identification of the anomaly cause, differentiating between natural and attack-related events, and the suggestion of the best mitigation strategy. In this work, the proposed framework is applied the Cyber Physical Systems scenario. More in detail, we focus on the distributed context analysis investigating the definition of a 2D representation of network traffic data. The suitability of four representation variables has been evaluated, and the variable selection has been performed.
在这篇文章中,通过探索两种类型的上下文:分布式和本地,提出了一个灵活的基于上下文的安全框架。前者包括处理来自一组空间分布的来源的信息,而后者涉及被监测系统周围的本地环境。联合处理这两种类型的信息可以识别异常原因,区分自然事件和攻击相关事件,并建议最佳缓解策略。在这项工作中,提出的框架应用于网络物理系统场景。更详细地说,我们关注分布式上下文分析,研究网络流量数据的二维表示的定义。评估了四个表征变量的适用性,并进行了变量选择。
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引用次数: 2
Static: Low Frequency Energy Harvesting and Power Transfer for the Internet of Things 静态:用于物联网的低频能量收集和功率传输
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2022-01-19 DOI: 10.3389/frsip.2021.763299
A. Thangarajan, T. D. Nguyen, Meng-Liang Liu, Sam Michiels, F. Yang, K. Man, Jieming Ma, W. Joosen, D. Hughes
The Internet of Things (IoT) is composed of wireless embedded devices which sense, analyze and communicate the state of the physical world. To achieve truly wireless operation, today’s IoT devices largely depend on batteries for power. However, this leads to high maintenance costs due to battery replacement, or the environmentally damaging concept of disposable devices. Energy harvesting has emerged as a promising approach to delivering long-life, environmentally friendly IoT device operation. However, with the exception of solar harvesting, it remains difficult to ensure sustainable system operation using environmental power alone. This paper tackles this problem by contributing Static, a Radio Frequency (RF) energy harvesting and wireless power transfer platform. Our approach comprises autonomous energy management techniques, adaptive power transfer algorithms and an open-source hardware reference platform to enable further research. We evaluate Static in laboratory conditions and show that 1) ambient RF energy harvesting can deliver sustainable operation using common industrial sources, while 2) wireless power transfer provides a simple means to power motes at a range of up to 3 m through a variety of media.
物联网(IoT)由无线嵌入式设备组成,这些设备可以感知、分析和通信物理世界的状态。为了实现真正的无线操作,当今的物联网设备在很大程度上依赖于电池供电。然而,由于更换电池,或者一次性设备对环境有害的概念,这导致了高昂的维护成本。能量收集已经成为提供长寿命、环保的物联网设备运行的一种有前途的方法。然而,除了太阳能收集之外,仅使用环境电力仍然难以确保系统的可持续运行。本文通过提供静态,射频(RF)能量收集和无线电力传输平台来解决这个问题。我们的方法包括自主能源管理技术、自适应电力传输算法和一个开源硬件参考平台,以实现进一步的研究。我们在实验室条件下评估了静态,并表明1)环境射频能量收集可以使用常见的工业源提供可持续的操作,而2)无线电力传输提供了一种简单的方法,可以通过各种介质在长达3米的范围内为motes供电。
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引用次数: 1
Optimization of Network Throughput of Joint Radar Communication System Using Stochastic Geometry 基于随机几何的联合雷达通信系统网络吞吐量优化
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2022-01-10 DOI: 10.3389/frsip.2022.835743
S. S. Ram, Shubhi Singhal, Gourab Ghatak
Recently joint radar communication (JRC) systems have gained considerable interest for several applications such as vehicular communications, indoor localization and activity recognition, covert military communications, and satellite based remote sensing. In these frameworks, bistatic/passive radar deployments with directional beams explore the angular search space and identify mobile users/radar targets. Subsequently, directional communication links are established with these mobile users. Consequently, JRC parameters such as the time trade-off between the radar exploration and communication service tasks have direct implications on the network throughput. Using tools from stochastic geometry (SG), we derive several system design and planning insights for deploying such networks and demonstrate how efficient radar detection can augment the communication throughput in a JRC system. Specifically, we provide a generalized analytical framework to maximize the network throughput by optimizing JRC parameters such as the exploration/exploitation duty cycle, the radar bandwidth, the transmit power and the pulse repetition interval. The analysis is further extended to monostatic radar conditions, which is a special case in our framework. The theoretical results are experimentally validated through Monte Carlo simulations. Our analysis highlights that for a larger bistatic range, a lower operating bandwidth and a higher duty cycle must be employed to maximize the network throughput. Furthermore, we demonstrate how a reduced success in radar detection due to higher clutter density deteriorates the overall network throughput. Finally, we show a peak reliability of 70% of the JRC link metrics for a single bistatic transceiver configuration.
最近,联合雷达通信(JRC)系统在一些应用中获得了相当大的兴趣,例如车辆通信、室内定位和活动识别、秘密军事通信和基于卫星的遥感。在这些框架中,双基地/无源雷达部署与定向波束探索角搜索空间和识别移动用户/雷达目标。随后,与这些移动用户建立定向通信链路。因此,雷达探测任务和通信服务任务之间的时间权衡等JRC参数直接影响网络吞吐量。利用随机几何(SG)的工具,我们得出了部署这种网络的几个系统设计和规划见解,并演示了有效的雷达探测如何增加JRC系统中的通信吞吐量。具体来说,我们提供了一个通用的分析框架,通过优化JRC参数(如勘探/开采占空比、雷达带宽、发射功率和脉冲重复间隔)来最大化网络吞吐量。分析进一步扩展到单站雷达条件,这是我们框架中的一个特殊情况。通过蒙特卡罗模拟实验验证了理论结果。我们的分析强调,对于更大的双基地范围,必须采用更低的工作带宽和更高的占空比来最大化网络吞吐量。此外,我们还演示了由于较高的杂波密度而降低的雷达探测成功率如何降低整体网络吞吐量。最后,我们展示了单个双站收发器配置的JRC链路指标的峰值可靠性为70%。
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引用次数: 8
Rethinking Pooling Operation for Liver and Liver-Tumor Segmentations 肝脏及肝肿瘤分割池化手术的再思考
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2022-01-10 DOI: 10.3389/frsip.2021.808050
Ju-hong Lei, Tao Lei, Weiqiang Zhao, Min-Qi Xue, Xiaogang Du, A. Nandi
Deep convolutional neural networks (DCNNs) have been widely used in medical image segmentation due to their excellent feature learning ability. In these DCNNs, the pooling operation is usually used for image down-sampling, which can gradually reduce the image resolution and thus expands the receptive field of convolution kernel. Although the pooling operation has the above advantages, it inevitably causes information loss during the down-sampling of the pooling process. This paper proposes an effective weighted pooling operation to address the problem of information loss. First, we set up a pooling window with learnable parameters, and then update these parameters during the training process. Secondly, we use weighted pooling to improve the full-scale skip connection and enhance the multi-scale feature fusion. We evaluated weighted pooling on two public benchmark datasets, the LiTS2017 and the CHAOS. The experimental results show that the proposed weighted pooling operation effectively improve network performance and improve the accuracy of liver and liver-tumor segmentation.
深度卷积神经网络(Deep convolutional neural network, DCNNs)由于其出色的特征学习能力,在医学图像分割中得到了广泛的应用。在这些DCNNs中,通常采用池化操作对图像进行下采样,这样可以逐渐降低图像分辨率,从而扩大卷积核的接受域。池化操作虽然具有上述优点,但在池化过程的下采样过程中不可避免地会造成信息丢失。本文提出了一种有效的加权池化操作来解决信息丢失问题。首先,我们建立一个具有可学习参数的池化窗口,然后在训练过程中更新这些参数。其次,利用加权池化方法改进全尺度跳跃连接,增强多尺度特征融合;我们在LiTS2017和CHAOS两个公共基准数据集上评估了加权池化。实验结果表明,所提出的加权池化操作有效地提高了网络性能,提高了肝脏和肝脏肿瘤分割的准确性。
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引用次数: 0
AIDA: An Active Inference-Based Design Agent for Audio Processing Algorithms AIDA:一种基于推理的音频处理算法设计代理
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2021-12-26 DOI: 10.3389/frsip.2022.842477
Albert Podusenko, B. V. Erp, Magnus T. Koudahl, B. Vries
In this paper we present Active Inference-Based Design Agent (AIDA), which is an active inference-based agent that iteratively designs a personalized audio processing algorithm through situated interactions with a human client. The target application of AIDA is to propose on-the-spot the most interesting alternative values for the tuning parameters of a hearing aid (HA) algorithm, whenever a HA client is not satisfied with their HA performance. AIDA interprets searching for the “most interesting alternative” as an issue of optimal (acoustic) context-aware Bayesian trial design. In computational terms, AIDA is realized as an active inference-based agent with an Expected Free Energy criterion for trial design. This type of architecture is inspired by neuro-economic models on efficient (Bayesian) trial design in brains and implies that AIDA comprises generative probabilistic models for acoustic signals and user responses. We propose a novel generative model for acoustic signals as a sum of time-varying auto-regressive filters and a user response model based on a Gaussian Process Classifier. The full AIDA agent has been implemented in a factor graph for the generative model and all tasks (parameter learning, acoustic context classification, trial design, etc.) are realized by variational message passing on the factor graph. All verification and validation experiments and demonstrations are freely accessible at our GitHub repository.
在本文中,我们提出了基于主动推理的设计代理(AIDA),这是一个基于主动推理的代理,它通过与人类客户端的位置交互迭代地设计个性化音频处理算法。AIDA的目标应用是,当HA客户端对其HA性能不满意时,当场为助听器(HA)算法的调优参数提出最有趣的替代值。AIDA将搜索“最有趣的选择”解释为最佳(声学)上下文感知贝叶斯试验设计的问题。在计算方面,AIDA被实现为具有预期自由能准则的主动推理代理,用于试验设计。这种类型的架构受到大脑中有效(贝叶斯)试验设计的神经经济学模型的启发,并意味着AIDA包括声学信号和用户反应的生成概率模型。我们提出了一种新的声信号生成模型,作为时变自回归滤波器和基于高斯过程分类器的用户响应模型。在生成模型的因子图中实现了完整的AIDA代理,所有任务(参数学习、声学上下文分类、试验设计等)都是通过因子图上的变分消息传递来实现的。所有的验证和验证实验和演示都可以在我们的GitHub存储库中免费访问。
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引用次数: 3
Multi-Frequency Radar Micro-Doppler Based Classification of Micro-Drone Payload Weight 基于多频雷达微多普勒的微型无人机载荷重量分类
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2021-12-22 DOI: 10.3389/frsip.2021.781777
D. Dhulashia, N. Peters, C. Horne, P. Beasley, M. Ritchie
The use of drones for recreational, commercial and military purposes has seen a rapid increase in recent years. The ability of counter-drone detection systems to sense whether a drone is carrying a payload is of strategic importance as this can help determine the potential threat level posed by a detected drone. This paper presents the use of micro-Doppler signatures collected using radar systems operating at three different frequency bands for the classification of carried payload of two different micro-drones performing two different motions. Use of a KNN classifier with six features extracted from micro-Doppler signatures enabled mean payload classification accuracies of 80.95, 72.50 and 86.05%, for data collected at S-band, C-band and W-band, respectively, when the drone type and motion type are unknown. The impact on classification performance of different amounts of situational information is also evaluated in this paper.
近年来,用于娱乐、商业和军事目的的无人机数量迅速增加。反无人机探测系统感知无人机是否携带有效载荷的能力具有战略重要性,因为这有助于确定被探测无人机构成的潜在威胁级别。本文介绍了使用在三个不同频段运行的雷达系统收集的微多普勒特征,用于对执行两种不同运动的两种不同微型无人机的携带有效载荷进行分类。使用从微多普勒特征中提取的六个特征的KNN分类器,当无人机类型和运动类型未知时,在s波段、c波段和w波段收集的数据的平均有效载荷分类准确率分别为80.95%、72.50%和86.05%。本文还评估了不同情景信息量对分类性能的影响。
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引用次数: 7
Persymmetric Adaptive Union Subspace Detection 超对称自适应联合子空间检测
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2021-12-15 DOI: 10.3389/frsip.2021.782182
Liyan Pan, Yongchan Gao, Z. Ye, Yuzhou Lv, Ming Fang
This paper addresses the detection of a signal belonging to several possible subspace models, namely, a union of subspaces (UoS), where the active subspace that generated the observed signal is unknown. By incorporating the persymmetric structure of received data, we propose three UoS detectors based on GLRT, Rao, and Wald criteria to alleviate the requirement of training data. In addition, the detection statistic and classification bound for the proposed detectors are derived. Monte-Carlo simulations demonstrate the detection and classification performance of the proposed detectors over the conventional detector in training-limited scenarios.
本文讨论了属于几个可能的子空间模型的信号的检测,即子空间的并集(UoS),其中产生观测信号的活动子空间是未知的。通过结合接收数据的超对称结构,我们提出了基于GLRT、Rao和Wald准则的三种UoS检测器,以减轻对训练数据的需求。此外,还推导了该检测器的检测统计量和分类界。蒙特卡罗仿真表明,在训练受限的情况下,该检测器的检测和分类性能优于传统检测器。
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引用次数: 0
Interference Utilization Precoding in Multi-Cluster IoT Networks 多集群物联网网络中的干扰利用预编码
Q3 ENGINEERING, ELECTRICAL & ELECTRONIC Pub Date : 2021-11-22 DOI: 10.3389/frsip.2021.761559
Yuanchen Wang, Eng Gee Lim, Xiaoping Xue, Guangyu Zhu, Rui Pei, Zhongxiang Wei
In Internet-of-Things, downlink multi-device interference has long been considered as a harmful element deteriorating system performance, and thus the principle of the classic interference-mitigation based precoding is to suppress the multi-device interference by exploiting the spatial orthogonality. In recent years, a judicious interference utilization precoding has been developed, which is capable of exploiting multi-device interference as a beneficial element for improving device’s reception performance, thus reducing downlink communication latency. In this review paper, we aim to review the emerging interference utilization precoding techniques. We first briefly introduce the concept of constructive interference, and then we present two generic downlink interference-utilization optimizations, which utilizes the multi-device interference for enhancing system performance. Afterwards, the application of interference utilization precoding is discussed in multi-cluster scenario. Finally, some open challenges and future research topics are envisaged.
在物联网中,下行链路多设备干扰一直被认为是影响系统性能的有害因素,因此经典的基于干扰缓解的预编码原理是利用空间正交性来抑制多设备干扰。近年来,人们开发了一种明智的干扰利用预编码,它能够将多设备干扰作为提高设备接收性能的有利因素,从而降低下行通信延迟。本文对近年来出现的干扰利用预编码技术进行了综述。本文首先简要介绍了相构干扰的概念,然后提出了两种通用的下行链路干扰利用优化方案,利用多设备干扰来提高系统性能。然后,讨论了干扰利用预编码在多集群场景中的应用。最后,展望了未来的研究课题。
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引用次数: 1
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Frontiers in signal processing
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