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STABILITY INDICATING REVERSE PHASE HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CHLORAMPHENICOL AND FLURBIPROFEN SODIUM IN PHARMACEUTICAL DOSAGE FORM 稳定性指示反相高效液相色谱法测定药品剂型中氯霉素和氟比洛芬钠含量的建立与验证
Pub Date : 2019-01-01 DOI: 10.21276/bpr.2019.9.1
Parikh N, P. N
Research Paper [DOI: 10.21276/bpr.2019.9.1] STABILITY INDICATING REVERSE PHASE HPLC METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF CHLORAMPHENICOL AND FLURBIPROFEN SODIUM IN PHARMACEUTICAL DOSAGE FORM Parikh N*, Patel N, Patel N Department of Quality Assurance, Arihant School of Pharmacy and Bio-Research Institute, Adalaj, Gandhinagar, Gujarat, India Bull. Pharm. Res. 2019;9(1-3):160. Received: January 25, 2019 / Accepted: April 25, 2019 Abstract References First Page Preview Download PDF Cited By
研究论文[DOI: 10.21276/bpr.2019.9.1]陈建军,陈建军,陈建军,陈建军,等。氯霉素和氟比洛芬钠的稳定性指示反相高效液相色谱法测定方法的建立与验证。制药。杂志2019;9(1 - 3):160。收稿日期:2019年1月25日/收稿日期:2019年4月25日摘要参考文献首页预览下载PDF
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引用次数: 0
DEMOGRAPHIC DISTRIBUTION OF DENTAL CARRIES IN NORTH INDIA 印度北部牙齿携带的人口分布
Pub Date : 2019-01-01 DOI: 10.21276/bpr.2019.9.5
Chandrul Kk, Yadav Ak, Maurya Sk, S. Kumar
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引用次数: 0
FORMULATION AND EVALUATION OF ANTIFUNGAL CREAM USING NELUMBO NUCIFERA AND AZADIRACHTA INDICA LEAVES EXTRACTS 荷叶和印楝叶提取物抗真菌乳膏的配方及评价
Pub Date : 2019-01-01 DOI: 10.21276/bpr.2019.9.8
M. Solanki, N. Jain, A Koshta, S. Malviya, A. Kharia
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引用次数: 0
STABILITY INDICATING RP-HPLC METHOD FOR DETERMINATION OF AMISULPRIDE IN TABLET DOSAGE FORM 稳定性指示反相高效液相色谱法测定片剂中氨硫pride的含量
Pub Date : 2019-01-01 DOI: 10.21276/bpr.2019.9.9
S. S
A new stability indicating RP-HPLC method was development and validation done for Amisulpride in tablet dosage form. RP-HPLC method was performed for estimation of dosage form and degradants. The method utilizes a mobile phase Acetonitrile:water in the ratio of 60:40 v/v and a flow rate of 1 ml/min with the UV detection at 226 nm for Amisulpride (AMP). The retention time was found to be 4.635 min for Amisulpride. The linearity was found to be in the concentration range of 5-30 μg/ml (r2=0.999) for AMP. Forced degradations were carried out under acid, base, thermal, photolytic and oxidative stress conditions. The method was satisfactorily validated as per the ICH guideline.
采用反相高效液相色谱法对氨硫pride片剂的稳定性进行了测定和验证。采用反相高效液相色谱法测定其剂型和降解物。该方法采用流动相乙腈:水,比为60:40 v/v,流速为1 ml/min,紫外检测波长为226 nm。结果表明,氨硫pride的保留时间为4.635 min。AMP在5 ~ 30 μg/ml的浓度范围内呈线性关系(r2=0.999)。在酸、碱、热、光解和氧化应激条件下均可进行强制降解。该方法按照ICH指南进行了令人满意的验证。
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引用次数: 4
BLOCK COPOLYMERIC MICELLES: BASIC CONCEPT AND PREPARATION TECHNIQUES 嵌段共聚胶束:基本概念和制备技术
Pub Date : 2019-01-01 DOI: 10.21276/bpr.2019.9.7
S. Dahiya
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引用次数: 1
DESIGN AND EVALUATION OF SUSTAINED RELEASE TABLETS OF TIMOLOL MALEATE 马来酸替马洛尔缓释片的设计与评价
Pub Date : 2019-01-01 DOI: 10.21276/bpr.2019.9.6
Rao Rj, Sattar Ma, Panda
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引用次数: 0
APPLICATION OF NANOCRYSTALS IN DRUG DELIVERY: AN OVERVIEW 纳米晶体在药物传递中的应用综述
Pub Date : 2018-12-01 DOI: 10.21276/bpr.2018.8.2.4
Dahiya S
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引用次数: 1
COMPARISON OF METHODS OF EXTERNAL AND INTERNAL STANDARD FOR GS DETERMINATION OF DOCOSAHEXAENOIC ACID gs测定二十二碳六烯酸外标法与内标法的比较
Pub Date : 2018-12-01 DOI: 10.21276/bpr.2018.8.2.3
Ivanov Sa, Tsvetkova Dd, Obreskova Dp
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引用次数: 0
D-OPTIMAL MIXTURE DESIGN FOR OPTIMIZATION OF SELF MICROEMULSIFYING DRUG DELIVERY SYSTEM OF SIMVASTATIN: CHARACTERIZATION AND IN VITRO EVALUATION 优化辛伐他汀自微乳化给药体系的d -最优混合物设计:表征及体外评价
Pub Date : 2018-12-01 DOI: 10.21276/bpr.2018.8.2.1
K. Patel, Ami Patel, Christian, Asha Patel, P. Shah, Gohel Mc
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引用次数: 0
EVALUATION OF MOTHERS’ KNOWLEDGE AND ATTITUDES OF ORAL REHYDRATION THERAPY IN CHILDHOOD DIARRHEA 母亲对儿童腹泻口服补液治疗知识和态度的评价
Pub Date : 2018-12-01 DOI: 10.21276/BPR.2018.8.2.2
J. Mo, G Abdulganiyu, Roland On, Bukola Gh
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引用次数: 1
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Bulletin of Pharmaceutical Research Institute
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