Pub Date : 2022-03-18DOI: 10.17352/2455-2968.000146
Beyzadeoglu Murat, Sager Omer, D. Selcuk, Dincoglan Ferrat
Objective: Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the most frequent cancer sites around the globe. Within the heterogeneous group of HNSCC, Oral Squamous Cell Carcinoma (OSCC) deserves the utmost attention as an important subsite. Despite multimodality management, recurrence of OSCC is not uncommon. RT may play an integral role as part of initial management or as adjunctive therapy, or for treatment of recurrent disease. In this study, we evaluate multimodality imaging-based RT treatment volume definition for irradiation of recurrent OSCC. Materials and methods: Multimodality imaging-based RT treatment volume definition for radiotherapeutic management of recurrent OSCC was assessed. RT target volume determination by incorporation of Magnetic Resonance Imaging (MRI) or by Computed Tomography (CT)-simulation images only has been evaluated and comparative analysis has been performed for patients receiving salvage RT for recurrent OSCC. Results: Ground truth target volume has been found to be identical with treatment volume definition by CT-MR fusion-based imaging. Conclusion: Incorporation of MRI in target and treatment volume definition may improve target and treatment volume definition for recurrent OSCC.
{"title":"Reappraisal of multimodality imaging for improved Radiation Therapy (RT) target volume determination of recurrent Oral Squamous Cell Carcinoma (OSCC): An original article","authors":"Beyzadeoglu Murat, Sager Omer, D. Selcuk, Dincoglan Ferrat","doi":"10.17352/2455-2968.000146","DOIUrl":"https://doi.org/10.17352/2455-2968.000146","url":null,"abstract":"Objective: Head and Neck Squamous Cell Carcinoma (HNSCC) is one of the most frequent cancer sites around the globe. Within the heterogeneous group of HNSCC, Oral Squamous Cell Carcinoma (OSCC) deserves the utmost attention as an important subsite. Despite multimodality management, recurrence of OSCC is not uncommon. RT may play an integral role as part of initial management or as adjunctive therapy, or for treatment of recurrent disease. In this study, we evaluate multimodality imaging-based RT treatment volume definition for irradiation of recurrent OSCC. Materials and methods: Multimodality imaging-based RT treatment volume definition for radiotherapeutic management of recurrent OSCC was assessed. RT target volume determination by incorporation of Magnetic Resonance Imaging (MRI) or by Computed Tomography (CT)-simulation images only has been evaluated and comparative analysis has been performed for patients receiving salvage RT for recurrent OSCC. Results: Ground truth target volume has been found to be identical with treatment volume definition by CT-MR fusion-based imaging. Conclusion: Incorporation of MRI in target and treatment volume definition may improve target and treatment volume definition for recurrent OSCC.","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":"66 20","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41246400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-02-07DOI: 10.17352/2455-2968.000145
James M Arul, R. Gavin, B. Neil, Lloyd David, N. G
Epinephrine is widely used in the management of severe cardiovascular instability as well as in cardiac arrest. In cardiac arrest, epinephrine has a standard dose (1mg) given at fixed intervals. We present a report on the use of high dose epinephrine (35mg in 45 minutes) during the successful management of a patient with sustained profound hypotension as a result of massive hemorrhage following laparoscopic adrenalectomy.
{"title":"High dose epinephrine in the management of life-threatening hypotension from post-surgical hemorrhage with an excellent outcome in a patient with Phaeochromocytoma: A case report","authors":"James M Arul, R. Gavin, B. Neil, Lloyd David, N. G","doi":"10.17352/2455-2968.000145","DOIUrl":"https://doi.org/10.17352/2455-2968.000145","url":null,"abstract":"Epinephrine is widely used in the management of severe cardiovascular instability as well as in cardiac arrest. In cardiac arrest, epinephrine has a standard dose (1mg) given at fixed intervals. We present a report on the use of high dose epinephrine (35mg in 45 minutes) during the successful management of a patient with sustained profound hypotension as a result of massive hemorrhage following laparoscopic adrenalectomy.","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-02-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48280916","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01Epub Date: 2022-09-26DOI: 10.17352/2455-2968.000150
Brandon Lucke-Wold, Michael Joseph Diaz, Joanna Song, Sai Batchu, Kevin Root, Karan Patel, Kamil Taneja
{"title":"The differential usage of molecular machinery in brain cancer patients with iron-enriched glioma environments.","authors":"Brandon Lucke-Wold, Michael Joseph Diaz, Joanna Song, Sai Batchu, Kevin Root, Karan Patel, Kamil Taneja","doi":"10.17352/2455-2968.000150","DOIUrl":"10.17352/2455-2968.000150","url":null,"abstract":"","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":"8 3","pages":"30-35"},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40673976","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-12-02DOI: 10.17352/2455-2968.000144
Perrotta Giulio
The "port-site metastasis" represents a tumor recurrence that develops in the abdominal wall within the scar tissue of the insertion site of one or more trocars, after laparoscopic surgery, not associated with peritoneal carcinomatosis. This last aspect is central because in the literature some isolated cases are reported, but most cases are associated with peritoneal carcinomatosis. The first case in the literature dates back to 1978 and in the literature, the incidence varies from 1% to 21%, although most published research reports a very small number of patients. Currently, the incidence in a specialized cancer center is consistent with the incidence of recurrence on a laparotomy scar. Possible mechanisms for cell implantation at the port site are direct implantation into the wound during forced, unprotected tissue retrieval or from contaminated instruments during tumor dissection; the effect of gas turbulence in lengthy laparoscopic procedures, and embolization of exfoliated cells during tumor dissection or hematogenous spread. Probably, however, the triggering mechanism is necessarily multifactorial. To date, the only significant prognostic factor in patients diagnosed with port-site metastasis is the interval between laparoscopy and the diagnosis of the port site: in fact, patients who develop the port site within 7 months after surgery have a generally worse prognosis, as well as port-site metastasis are more frequent in advanced cancers and the presence of ascites. To reduce the risk, the following measures are proposed in the literature: 1) Select the patient who does not have a metastatic oncologic condition or friable cancerous masses or lymph node spread or attached external or intracystic vegetations, preferring well-localized, benign or low-malignant or otherwise intact tumors; 2) Use wound protectors and use of protective bags (or endo bag) for tissue retrieval; 3) Peritoneal washing with heparin, to prevent free cell adhesion, or washing with cytocidal solutions. Evaluate the utility of using Povidone-iodine, Taurolidine (which has anti-adhesion activity and decreases proangiogenic factors), and chemotherapy products; 4) Avoid removing pneumoperitoneum with trocars in place; 5) Avoiding direct contact between the solid tumor and the port site; 6) Prefer laparoscopy to laparotomy, if possible; 7) Avoid the use of gas or direct CO2 insufflation, although in literature the point is controversial and deserves more attention and study, as the initial hypothesis that CO2 increased the invasion capacity of tumor cells (in vitro and in vivo) has been refuted several times. Insufflation of hyperthermic CO2 and humidified CO2 leads to a better outcome in patients with a malignant tumor who undergo a laparoscopic procedure compared with normal CO2 pneumoperitoneum; 8) Comply with surgical protocols and techniques by updating one's surgical skills, as it has been demonstrated, as already reported here, the presence of cancerous cells on instr
{"title":"Port-Site Metastasis (PSM): Definition, clinical contexts and possible preventive actions to reduce risk","authors":"Perrotta Giulio","doi":"10.17352/2455-2968.000144","DOIUrl":"https://doi.org/10.17352/2455-2968.000144","url":null,"abstract":"The \"port-site metastasis\" represents a tumor recurrence that develops in the abdominal wall within the scar tissue of the insertion site of one or more trocars, after laparoscopic surgery, not associated with peritoneal carcinomatosis. This last aspect is central because in the literature some isolated cases are reported, but most cases are associated with peritoneal carcinomatosis. The first case in the literature dates back to 1978 and in the literature, the incidence varies from 1% to 21%, although most published research reports a very small number of patients. Currently, the incidence in a specialized cancer center is consistent with the incidence of recurrence on a laparotomy scar. Possible mechanisms for cell implantation at the port site are direct implantation into the wound during forced, unprotected tissue retrieval or from contaminated instruments during tumor dissection; the effect of gas turbulence in lengthy laparoscopic procedures, and embolization of exfoliated cells during tumor dissection or hematogenous spread. Probably, however, the triggering mechanism is necessarily multifactorial. To date, the only significant prognostic factor in patients diagnosed with port-site metastasis is the interval between laparoscopy and the diagnosis of the port site: in fact, patients who develop the port site within 7 months after surgery have a generally worse prognosis, as well as port-site metastasis are more frequent in advanced cancers and the presence of ascites. To reduce the risk, the following measures are proposed in the literature: 1) Select the patient who does not have a metastatic oncologic condition or friable cancerous masses or lymph node spread or attached external or intracystic vegetations, preferring well-localized, benign or low-malignant or otherwise intact tumors; 2) Use wound protectors and use of protective bags (or endo bag) for tissue retrieval; 3) Peritoneal washing with heparin, to prevent free cell adhesion, or washing with cytocidal solutions. Evaluate the utility of using Povidone-iodine, Taurolidine (which has anti-adhesion activity and decreases proangiogenic factors), and chemotherapy products; 4) Avoid removing pneumoperitoneum with trocars in place; 5) Avoiding direct contact between the solid tumor and the port site; 6) Prefer laparoscopy to laparotomy, if possible; 7) Avoid the use of gas or direct CO2 insufflation, although in literature the point is controversial and deserves more attention and study, as the initial hypothesis that CO2 increased the invasion capacity of tumor cells (in vitro and in vivo) has been refuted several times. Insufflation of hyperthermic CO2 and humidified CO2 leads to a better outcome in patients with a malignant tumor who undergo a laparoscopic procedure compared with normal CO2 pneumoperitoneum; 8) Comply with surgical protocols and techniques by updating one's surgical skills, as it has been demonstrated, as already reported here, the presence of cancerous cells on instr","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-12-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45399342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-08-20DOI: 10.17352/2455-2968.000143
Mallik Mainak, R. Sunil Kumar, Sahu Ranjit Kumar
BackgroundCOVID-19 pandemic has wreaked havoc on Plastic Surgery practices globally. The superior forms of reconstruction or repair take long operative hours, more surgical team members and invasive post-operative monitoring which impose substantial risk of acquiring the infection. Having faced the numerous issues, we considered basic “old school” reconstructive strategies over the ideal ones during this pandemic and realized their importance. MethodIn this retrospective study period of one year, the patients whom we had earlier planned for a superior form of reconstruction, but ultimately had to be managed in a basic, safe, quick and “old school” ways, were included. The details of the changed plans of reconstruction or repair, the operative time, number of team members, post-operative stay and other data were retrieved and analysed. ResultsAmong the 30 patients included, the mean age was 39.9 years, with male to female ratio of 3:2. The mean operative time was 64.7 minutes and the mean number of surgical team members was 2.5. The mean period of post-operative inpatient stay was 2.4 days. 16.7% of patients were infected by COVID-19 within the immediate 2 weeks of post-operative period but with no mortality. The mean period of OPD follow-up was 5.5 days after discharge with 20% overall complications. ConclusionIn this diffi cult time of the COVID pandemic, the basic and fundamental surgical plans of repair and reconstruction still hold their signifi cance and should be considered to achieve the reconstructive goals.
{"title":"Back to Basics – The best approach in reconstructive surgery to tide over the COVID pandemic crisis","authors":"Mallik Mainak, R. Sunil Kumar, Sahu Ranjit Kumar","doi":"10.17352/2455-2968.000143","DOIUrl":"https://doi.org/10.17352/2455-2968.000143","url":null,"abstract":"BackgroundCOVID-19 pandemic has wreaked havoc on Plastic Surgery practices globally. The superior forms of reconstruction or repair take long operative hours, more surgical team members and invasive post-operative monitoring which impose substantial risk of acquiring the infection. Having faced the numerous issues, we considered basic “old school” reconstructive strategies over the ideal ones during this pandemic and realized their importance. MethodIn this retrospective study period of one year, the patients whom we had earlier planned for a superior form of reconstruction, but ultimately had to be managed in a basic, safe, quick and “old school” ways, were included. The details of the changed plans of reconstruction or repair, the operative time, number of team members, post-operative stay and other data were retrieved and analysed. ResultsAmong the 30 patients included, the mean age was 39.9 years, with male to female ratio of 3:2. The mean operative time was 64.7 minutes and the mean number of surgical team members was 2.5. The mean period of post-operative inpatient stay was 2.4 days. 16.7% of patients were infected by COVID-19 within the immediate 2 weeks of post-operative period but with no mortality. The mean period of OPD follow-up was 5.5 days after discharge with 20% overall complications. ConclusionIn this diffi cult time of the COVID pandemic, the basic and fundamental surgical plans of repair and reconstruction still hold their signifi cance and should be considered to achieve the reconstructive goals.","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43754558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-19DOI: 10.17352/2455-2968.000133
Sager Omer, D. Selcuk, Dincoglan Ferrat, Beyzadeoglu Murat
Abdominal wall reconstruction and hernia repair surgery continue to evolve with the intention to successfully repair the abdominal wall,
腹壁重建和疝修补手术继续发展，目的是成功地修补腹壁，
{"title":"Assessment of posterior fossa target definition by multimodality imaging for patients with medulloblastoma","authors":"Sager Omer, D. Selcuk, Dincoglan Ferrat, Beyzadeoglu Murat","doi":"10.17352/2455-2968.000133","DOIUrl":"https://doi.org/10.17352/2455-2968.000133","url":null,"abstract":"Abdominal wall reconstruction and hernia repair surgery continue to evolve with the intention to successfully repair the abdominal wall,","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45171597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-19DOI: 10.17352/2455-2968.000134
Sager Omer, Dincoglan Ferrat, D. Selcuk, Beyzadeoglu Murat
Abdominal wall reconstruction and hernia repair surgery continue to evolve with the intention to successfully repair the abdominal wall,
腹壁重建和疝修补手术继续发展，目的是成功地修补腹壁，
{"title":"Radiation Therapy (RT) target determination for irradiation of bone metastases with soft tissue component: Impact of multimodality imaging","authors":"Sager Omer, Dincoglan Ferrat, D. Selcuk, Beyzadeoglu Murat","doi":"10.17352/2455-2968.000134","DOIUrl":"https://doi.org/10.17352/2455-2968.000134","url":null,"abstract":"Abdominal wall reconstruction and hernia repair surgery continue to evolve with the intention to successfully repair the abdominal wall,","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47254343","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-03-10DOI: 10.17352/2455-2968.000132
A. Ashraf, Uddin Md Masleh, Ahmad Nehal, Jawed Shakil
Abdominal wall reconstruction and hernia repair surgery continue to evolve with the intention to successfully repair the abdominal wall,
腹壁重建和疝修补手术继续发展，目的是成功地修补腹壁，
{"title":"Study of a preoperative scoring system to predict difficult laparoscopic cholecystectomy","authors":"A. Ashraf, Uddin Md Masleh, Ahmad Nehal, Jawed Shakil","doi":"10.17352/2455-2968.000132","DOIUrl":"https://doi.org/10.17352/2455-2968.000132","url":null,"abstract":"Abdominal wall reconstruction and hernia repair surgery continue to evolve with the intention to successfully repair the abdominal wall,","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44658221","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-25DOI: 10.17352/2455-3068.000131
Smith Howard N
{"title":"The medical liability litigation industry and how to defeat it - A challenge for management science","authors":"Smith Howard N","doi":"10.17352/2455-3068.000131","DOIUrl":"https://doi.org/10.17352/2455-3068.000131","url":null,"abstract":"","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43259200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-02-25DOI: 10.17352/2455-2968.000131
Howard Smith
Suspicion of fault is toxic to a trusting relationship between physicians and patients. It is even more toxic to the interest of justice. A medical liability litigation industry rises from this suspicion of fault and prospers at the expense of physicians, patients and justice. Lawyers are part of the medical liability litigation industry; so, too, are expert witnesses, who are also physicians. Byrom vs. Johns Hopkins Bayview Medical Center is illustrative of the impact of suspicion of fault. Inductive reasoning is the conventional way lawsuits are argued. It is the critical success factor used by lawyers and expert witnesses on both sides to showcase their most favorable evidence. However, deductive reasoning is also an acceptable form of legal reasoning. It is completely consistent with the ethical requirement of doctors acting in the capacity of medical experts to remain objective. It analyzes all evidence, favorable or not. Although organized medicine has authority over doctors who are expert witnesses, until now, it does nothing to hold expert witnesses accountable to ethical obligations. The consequences are verdicts like that of Byrom vs Johns Hopkins. Healthcare management science offers a solution to this dilemma. A methodology of deductive reasoning, which is used as a best practice for medical experts, is a means to hold experts accountable to the highest principles of jurisprudence and professional ethics and separates experts from the interests of the medical liability litigation industry.
{"title":"The medical liability litigation industry and how to defeat it - A challenge for management science","authors":"Howard Smith","doi":"10.17352/2455-2968.000131","DOIUrl":"https://doi.org/10.17352/2455-2968.000131","url":null,"abstract":"Suspicion of fault is toxic to a trusting relationship between physicians and patients. It is even more toxic to the interest of justice. A medical liability litigation industry rises from this suspicion of fault and prospers at the expense of physicians, patients and justice. Lawyers are part of the medical liability litigation industry; so, too, are expert witnesses, who are also physicians. Byrom vs. Johns Hopkins Bayview Medical Center is illustrative of the impact of suspicion of fault. Inductive reasoning is the conventional way lawsuits are argued. It is the critical success factor used by lawyers and expert witnesses on both sides to showcase their most favorable evidence. However, deductive reasoning is also an acceptable form of legal reasoning. It is completely consistent with the ethical requirement of doctors acting in the capacity of medical experts to remain objective. It analyzes all evidence, favorable or not. Although organized medicine has authority over doctors who are expert witnesses, until now, it does nothing to hold expert witnesses accountable to ethical obligations. The consequences are verdicts like that of Byrom vs Johns Hopkins. Healthcare management science offers a solution to this dilemma. A methodology of deductive reasoning, which is used as a best practice for medical experts, is a means to hold experts accountable to the highest principles of jurisprudence and professional ethics and separates experts from the interests of the medical liability litigation industry.","PeriodicalId":93785,"journal":{"name":"Journal of surgery and surgical research","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2021-02-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44572837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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