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Is 5 IU bolus of oxytocin as effective as 10 IU bolus for control of bleeding during cesarean section under spinal anesthesia? 在脊髓麻醉下剖宫产术中,5iu剂量的催产素与10iu剂量的催产素一样有效吗?
Pub Date : 2017-01-01 DOI: 10.4103/archms.archms_32_17
Musa M Yusuf, E. Nwasor, R. Mohammed
Aim and Objectives: We sought to compare the hemodynamic effects of 5 international unit (IU) and 10 IU of intravenous (IV) boluses of oxytocin and their efficacy in reducing blood loss during cesarean section and also to determine the incidence of postoperative nausea and vomiting (PONV) and postdural puncture headache (PDPH). Patients and Methods: One hundred and ten parturients of American Society of Anesthesiologists' I and II scheduled for cesarean section under spinal anesthesia were randomized into two groups. Group A (n = 55) received 5 IU IV bolus of oxytocin and Group B (n = 55) received 10 IU IV bolus of oxytocin after delivery. Ten milliliters per kilogram of 0.9% saline was administered to both groups as volume preload. Subarachnoid block was performed with size 24G spinal needles at L2/L3 or L3/L4 intervertebral space with the patients in sitting position. Two milliliters of 0.5% heavy bupivacaine was administered slowly intrathecally. Following delivery of the baby, IV boluses of 5 IU (Group A) or 10 IU (Group B) of oxytocin were administered slowly, and recording of heart rate, systolic, diastolic, and mean arterial blood pressure was done every minute for 5 min after bolus injection. IV infusion of 30 IU of oxytocin in 500 ml of 0.9% saline (60 mU/ml) at a rate of 125 ml/h was continued in both groups till the end of surgery. Estimated blood loss (EBL) was assessed by visual estimation. Patients were monitored continuously until 24 h after surgery to evaluate PDPH and PONV. Results: There were no statistically significant differences in the EBL between the two groups. There was no significant rise in heart rate and no significant decrease in mean arterial blood pressure in Group A compared to Group B. The incidence of PDPH and PONV was also comparable in both groups. Conclusion: Five IU of IV bolus of oxytocin is as effective as 10 IU of IV bolus in reducing blood loss during cesarean section.
目的和目的:我们试图比较5国际单位(IU)和10国际单位静脉注射(IV)后叶催产素的血流动力学效果及其减少剖宫产术中出血量的效果,并确定术后恶心呕吐(PONV)和硬脊膜穿刺后头痛(PDPH)的发生率。患者与方法:选取110例美国麻醉医师学会I、II期剖宫产麻下剖宫产术患者,随机分为两组。A组(n = 55)产后给予5 IU静脉注射催产素,B组(n = 55)产后给予10 IU静脉注射催产素。两组均给予每千克0.9%生理盐水10毫升作为体积预负荷。患者坐位,在L2/L3或L3/L4椎间隙用24G大小的脊髓针进行蛛网膜下腔阻滞。2毫升0.5%重布比卡因在鞘内缓慢注射。分娩后,缓慢静脉注射5 IU (A组)或10 IU (B组)的催产素,每分钟记录一次心率、收缩压、舒张压和平均动脉血压,持续5分钟。两组患者持续以125 ml/h的速度在0.9%生理盐水500 ml (60 mU/ml)中静脉滴注催产素30 IU,直至手术结束。估计失血量(EBL)采用目测法评估。持续监测患者至术后24小时,评估PDPH和PONV。结果:两组患者EBL差异无统计学意义。与b组相比,A组患者心率无明显升高,平均动脉血压无明显降低。两组患者PDPH和PONV的发生率也具有可比性。结论:5 IU静脉滴注催产素与10 IU静脉滴注减少剖宫产术出血量的效果相同。
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引用次数: 2
Does implementation of preanesthesia assessment clinics improve surgical patients care in Nigeria? 麻醉前评估诊所的实施是否改善了尼日利亚手术患者的护理?
Pub Date : 2017-01-01 DOI: 10.4103/archms.archms_10_17
S. Yakubu
Introduction: Preanesthesia assessment of patients is a major component of the perioperative care of surgical patients. The benefits of outpatient preoperative assessment clinics (PAC) were recognized over 67 years ago. However, these clinics are not used in Nigeria as part of surgical care. Search of the literature did not reveal any hospital in Nigeria that operates PAC, and therefore, its implementation in this country is still in process. This may not be unconnected with scarce financial, material, and human resources. Materials and Methods: This study was a questionnaire survey of the views of anesthetists, surgeons, and hospital administrators in some Nigerian Federal Teaching Hospitals on the usefulness and limitations of PAC. Structured questionnaires were sent to surgeons, anesthetists and Chairmen, Medical Advisory Committees in the selected Hospitalsand the results were analyzed. Results: Respondents indicated the benefits of preanesthesia assessment clinics as decrease in the incidence of surgery delays and cancelations, shorter lengths of hospital stay, improvement in the logistics of preoperative preparation, improved patient knowledge of anesthesia, and preoperative care as well as the role of the anesthetist in surgical care. Limiting factors to successful preanesthesia clinics were lack of cooperation from anesthetists and surgeons, other medical specialists, lack of supporting staff, finance, and appropriate office space. Conclusions: Preanesthesia assessment clinic increases the overall efficiency of the period of stay of the surgical patient in the hospital. Its benefits outweigh its disadvantages, and its successful implementation requires effort, time, money, and close collaboration with hospital administrators.
患者麻醉前评估是外科患者围手术期护理的重要组成部分。门诊术前评估诊所(PAC)的好处在67年前就得到了认可。然而,这些诊所在尼日利亚不被用作外科护理的一部分。查阅文献并没有发现尼日利亚有任何一家医院实施PAC,因此,该方案在该国的实施仍在进行中。这可能与稀缺的财政、物质和人力资源不无关系。材料与方法:本研究对尼日利亚部分联邦教学医院的麻醉师、外科医生和医院管理人员对PAC的有用性和局限性的看法进行问卷调查,并向所选医院的外科医生、麻醉师和医学咨询委员会主席发送结构化问卷,并对结果进行分析。结果:受访者表示,麻醉前评估诊所的好处是手术延误和取消的发生率降低,住院时间缩短,术前准备的后勤改善,提高患者对麻醉的了解,术前护理以及麻醉师在手术护理中的作用。麻醉前诊所成功的限制因素是缺乏麻醉师和外科医生、其他医学专家的合作、缺乏辅助人员、资金和适当的办公空间。结论:麻醉前评估门诊提高了手术患者住院期的整体效率。它的优点大于缺点,它的成功实施需要努力、时间、金钱以及与医院管理人员的密切合作。
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引用次数: 0
Prevalence of obesity and outcome of weight loss on reproduction: A study among women attending infertility clinic in Zaria, Northern Nigeria 肥胖患病率和体重减轻对生殖的影响:尼日利亚北部扎里亚不孕不育诊所妇女的一项研究
Pub Date : 2017-01-01 DOI: 10.4103/archms.archms_25_17
Y. Aliyu, A. Adesiyun, S. Avidime, A. Randawa
Objective: Obesity is rising in the developing countries because of changing life style, and this has its burden on fertility and its management. This study determined the prevalence of obesity and clinical correlation of obesity with menstrual abnormalities, as well as the rate of spontaneous conception among obese infertile women on nonsurgical weight loss therapy. Methodology: A cross-sectional longitudinal study was done among women that presented with infertility to the gynecology clinic. The main outcomes measured were percentage of infertile women that are obese, menstrual pattern of these women, and spontaneous conception among obese infertile women following weight loss therapy. Results: Of the 205 patients, 68 (33.2%) were found to be obese; there was a significant association between obesity and abnormal menstrual pattern (P = 0.0002). Oligomenorrhea and hypomenorrhea were also found to be significantly associated with obesity (P = 0.009 and P = 0.022, respectively). Following average of 12-month follow up, spontaneous conception among obese infertile women while on weight loss therapy was 21.1%. Conclusion: The prevalence of obesity was high with a significant association between obesity and menstrual abnormalities. Weight loss among obese infertile women led to improvement in spontaneous conception.
目的:由于生活方式的改变,肥胖在发展中国家正在上升,这给生育和管理带来了负担。本研究确定了在接受非手术减肥治疗的肥胖不育妇女中肥胖的患病率、肥胖与月经异常的临床相关性以及自然受孕率。方法学:横断面纵向研究中,妇女提出不孕不育妇科诊所。测量的主要结果是肥胖不孕妇女的百分比,这些妇女的月经模式,以及肥胖不孕妇女在减肥治疗后的自然受孕。结果:205例患者中,肥胖68例(33.2%);肥胖与月经异常有显著相关性(P = 0.0002)。经少、经少也与肥胖显著相关(P = 0.009、P = 0.022)。在平均12个月的随访中,接受减肥治疗的肥胖不孕妇女的自然受孕率为21.1%。结论:肥胖患病率高,且肥胖与月经异常有显著相关性。肥胖不孕妇女的体重减轻导致自然受孕的改善。
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引用次数: 1
Serostatus disclosure to sexual partner by human immunodeficiency virus-positive clients receiving antiretroviral therapy in a tertiary health facility in Northwest Nigeria 尼日利亚西北部三级卫生设施中接受抗逆转录病毒治疗的人类免疫缺陷病毒阳性病人向性伴侣透露的血清状况
Pub Date : 2017-01-01 DOI: 10.4103/archms.archms_15_17
S. Bashir, M. Ibrahim, Matthias O Ekpenukpang, Saifuddin Ahmed
Background: Disclosure of human immunodeficiency virus (HIV)-positive status to sexual partner is crucial and helpful for treatment adherence, HIV transmission reduction, PMTCT interventions, partner testing and acceptance of referrals for HIV-related care, treatment and support. This study assessed the awareness, practices as well as factors associated with serostatus disclosure among HIV positive clients receiving anti-retroviral treatment in a tertiary health facility in northwest Nigeria. Methodology: A cross-sectional study was conducted among 129 HIV positive clients receiving anti-retroviral therapy selected using a systematic random sampling technique. Data were collected using a structured interviewer-administered questionnaire containing open- and close-ended questions, and analyzed using SPSS Statistics version 21.0. Result: The mean age of respondents was 38.0 ± 10.6 years and most (89.9%) of the respondents were on antiretroviral therapy for more than one year. Majority of the respondents have a positive attitude to serostatus disclosure (67.4%) and have disclosed their serostatus to their partner (79.8%), but only 57.3% did so within one month of knowing their serostatus. Their main reason for disclosure were concern for partner's health (74.6%) while partners' reactions were supportive in 35% and understanding in 21.4% of respondents. Disclosure was high among those currently married (odds ratio = 0.075 96% confidence interval: 0.0230-0.237, P = 0.001) but there was no statistically significant association between disclosure and age, gender, religion, educational status and average monthly income. Conclusion: This study found a good partner disclosure rate of HIV serostatus among PLWHA receiving treatment at Nasara Clinic, ABUTH, and client's marital status as currently married was a significant factor that influenced disclosure rate.
背景:向性伴侣披露人类免疫缺陷病毒(HIV)阳性状况至关重要,有助于坚持治疗、减少艾滋病毒传播、预防母婴传播干预、伴侣检测和接受转介接受艾滋病毒相关护理、治疗和支持。本研究评估了尼日利亚西北部一家三级医疗机构中接受抗逆转录病毒治疗的艾滋病毒阳性患者的认识、做法以及与血清状态披露相关的因素。方法:采用系统随机抽样技术,对129名接受抗逆转录病毒治疗的艾滋病毒阳性患者进行了横断面研究。数据收集采用结构化问卷调查,包括开放式和封闭式问题,并使用SPSS统计21.0版进行分析。结果:受访患者平均年龄为38.0±10.6岁,接受抗逆转录病毒治疗1年以上的占89.9%。大部分受访者(67.4%)对披露自己的服务状况持积极态度,并曾向伴侣披露自己的服务状况(79.8%),但只有57.3%的受访者在知道自己的服务状况后一个月内披露了自己的服务状况。他们透露的主要原因是担心伴侣的健康(74.6%),而伴侣的反应是支持(35%)和理解(21.4%)。已婚人群的信息披露率较高(优势比为0.075,96%可信区间为0.0230 ~ 0.237,P = 0.001),但信息披露与年龄、性别、宗教、教育程度和平均月收入之间无统计学意义相关。结论:本研究发现在Nasara诊所和ABUTH接受治疗的PLWHA患者的HIV血清状况的伴侣检出率良好,而患者的婚姻状况是否已婚是影响检出率的重要因素。
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引用次数: 3
Malrotation with midgut volvulus and bowel gangrene in a 45-year-old man 45岁男性,旋转不良伴中肠扭转及肠坏疽
Pub Date : 2017-01-01 DOI: 10.4103/archms.archms_2_16
S. Kache, D. Sale, Nuhu Yusuf, J. Makama
Midgut volvulus due to intestinal malrotation is a rare occurrence in adult life. Malrotation is a congenital, developmental anomaly that results from an arrest of the physiological rotation of the gut through 270°. It is often thought that complications due to it, present themselves early during childhood and rarely occur among adults. However, a few cases have occurred and have been reported among adults. When it does occur in adults, it is often associated with catastrophic consequences. We present the case of a 45-year-old man with malrotation resulting in midgut volvulus. Our patient is a 45-year-old man, who presented with sudden onset of colicky abdominal pain and abdominal swelling of 24 h duration. He had been having recurrent abdominal pain since childhood. Physical examination revealed a patient in shock with markedly distended abdomen and anterior abdominal wall edema. Plain abdominal X-ray showed multiple air-fluid levels with thickened bowel outline. A diagnosis of intestinal obstruction was made. The patient was fully resuscitated and planned for emergency exploratory laparotomy under general anesthesia. Intraoperative findings revealed a 360° clockwise rotation of the small bowel around the mesenteric pedicle of the superior mesenteric artery and vein including about 350 cm of bowel gangrene. Resection and anastomosis were done. The early postoperative period was uneventful. However, he had anastomotic dehiscence on the 5th postoperative day and had to be reoperated but sadly he died 24 h later due to complications of anesthesia. Nonspecific recurrent abdominal complaints in adults of any age should raise suspicion of the possibility of a midgut malrotation or malfixation with or without intermittent volvulus. This case highlights the importance of early diagnosis and treatment.
由于肠道旋转不良引起的中肠扭转在成人生活中是罕见的。旋转不良是一种先天性的发育异常,是由于肠道270°的生理旋转停止造成的。人们通常认为,它引起的并发症在儿童早期出现,很少发生在成人中。然而,在成年人中已经发生和报告了少数病例。当它确实发生在成年人身上时,往往伴随着灾难性的后果。我们提出的情况下,45岁的男性与旋转不良导致中肠扭转。我们的病人是一名45岁的男性,他表现为突然发作的绞痛腹痛和腹部肿胀,持续24小时。他从小就反复发作腹痛。体格检查发现病人有明显的腹部膨胀和前腹壁水肿。腹部x线平片显示多个气液面,肠壁增厚。诊断为肠梗阻。患者完全复苏,并计划在全身麻醉下进行紧急剖腹探查术。术中发现小肠绕肠系膜上动静脉的肠系膜蒂顺时针旋转360°,包括约350 cm的肠坏疽。切除并吻合。术后早期平安无事。术后第5天吻合口裂开,再次手术,24 h后因麻醉并发症死亡。任何年龄的成人的非特异性复发性腹部主病应引起对中肠旋转不良或固定不良伴或不伴间歇性扭转的可能性的怀疑。这个病例强调了早期诊断和治疗的重要性。
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引用次数: 1
Is acute appendicitis still the most common abdominal surgical emergency 急性阑尾炎仍然是最常见的腹部外科急症吗
Pub Date : 2017-01-01 DOI: 10.4103/archms.archms_40_17
J. Makama
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引用次数: 3
Reproductive health decision-making among adolescents in public secondary schools in Zaria, North-Western, Nigeria 尼日利亚西北部扎里亚公立中学青少年的生殖健康决策
Pub Date : 2017-01-01 DOI: 10.4103/archms.archms_22_17
M. Ibrahim, S. A. Adamu, M. Yakubu, S. Bashir
Introduction: Risky sexual behavior among adolescents is a major contributory factor to adolescent morbidity. This is mainly because during adolescence, cognitive, and psychological maturity coupled with increased need for autonomy translates into a greater desire for independent decision-making. The study assessed reproductive health decision-making and its sociodemographic determinants among adolescent senior secondary school students. Methods: This was a cross-sectional study involving 384 adolescent senior secondary school students selected through multi-stage sampling. Data were collected through a self-administered questionnaire and analyzed using IBM SPSS Statistics version 20 and results are presented in tables and charts. Results: Mean age of the respondents was 17.5 ± 1.3 years, and 170 (44.6%) were <18 years old. Reproductive health decision-making was good in 116 (30.1%). If they were sexually abused, 187 (48.4%) said that they would report first to their parents. Reproductive health decision-making showed statistically significant association with gender (P = 0.04), and class of the study (P < 0.0001), but not with age (P = 0.24), ethnicity (P = 0.86), religion (P = 0.16), and marital status (P = 0.99). Conclusion: Reproductive health decision was generally poor, and it was influenced by gender and class of the study. Therefore, Government should consider ways of improving reproductive health decision-making among the secondary school students, possibly by including it in their school curriculum. Future studies should identify locally applicable interventions to promote parent–child connectedness for improving reproductive health decision-making among adolescents.
青少年危险性行为是青少年发病的一个主要因素。这主要是因为在青春期,认知和心理成熟,加上自主性需求的增加,转化为更大的独立决策的愿望。该研究评估了青春期高中生的生殖健康决策及其社会人口学决定因素。方法:采用多阶段抽样方法,对384名初中生进行横断面研究。通过自我管理的问卷收集数据,并使用IBM SPSS Statistics version 20进行分析,结果以表格和图表的形式呈现。结果:调查对象平均年龄为17.5±1.3岁,其中<18岁者170例(44.6%)。116例(30.1%)生殖健康决策良好。如果受到性侵害,187人(48.4%)表示会先向父母举报。生殖健康决策与性别(P = 0.04)、研究类别(P < 0.0001)相关,与年龄(P = 0.24)、种族(P = 0.86)、宗教(P = 0.16)、婚姻状况(P = 0.99)无关。结论:生殖健康决策普遍较差,受性别和班级的影响。因此,政府应考虑如何改进中学生的生殖健康决策,可能将其纳入学校课程。未来的研究应确定当地适用的干预措施,以促进亲子联系,改善青少年的生殖健康决策。
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引用次数: 0
Infected huge prolapsed polypoidal fibroid: Issues of neglect and delayed access to surgical treatment 感染巨大脱垂的息肉样肌瘤:忽视和延迟获得手术治疗的问题
Pub Date : 2016-07-01 DOI: 10.4103/archms.archms_5_17
F. Bakari, Moroof Suleman Omobayowa, A. Adesiyun, H. Sulayman, N. Ameh, Hauwa Umar Shuaib
Gravitational pull and subtle uterine contractions on huge polypoidal submucous uterine fibroid may dilate the cervix and prolapse into the vagina. Such prolapsed fibroid can either be removed through the vaginal route if it is connected with a long stalk or through an abdominal route if it has a broad base or if it is coexisting with multiple uterine fibroids. We present two cases of grand multiparous women with huge prolapsed submucous fibroids where neglect led to presentation with life-threatening infection and bleeding.
巨大的息肉状粘膜下子宫肌瘤的重力牵拉和微妙的子宫收缩可能使子宫颈扩张并脱垂到阴道。这种脱垂的肌瘤,如果有长柄连接,可以通过阴道途径切除;如果基底较宽,可以通过腹部途径切除或同时存在多个子宫肌瘤。我们报告两例大产妇女有巨大脱垂的粘膜下肌瘤,忽视导致了危及生命的感染和出血。
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引用次数: 0
Pattern of anterior segment eye disorders in diabetic patients attending Aminu Kano Teaching Hospital, Kano, Nigeria 在尼日利亚卡诺阿米努卡诺教学医院就诊的糖尿病患者前段眼病的模式
Pub Date : 2016-07-01 DOI: 10.4103/archms.archms_3_16
A. Lawan, L. Abdu, V. Pam
Background: The aim of the study is to determine the pattern, frequency, and types of anterior segment disorders in diabetic patients attending the outpatient specialist Diabetes Clinic of Aminu Kano Teaching Hospital (AKTH), Kano. Patients and Methods: This was a descriptive cross-sectional study of diabetic patients in AKTH over a 1-year period. Sample size was estimated using Fisher's formula, and systematic sampling was done to ensure proper randomization of patients that fulfilled the study criteria. Information obtained included patients' bio-data, height, weight, fasting blood sugar (FBS), type and duration of diabetes, associated comorbidities; visual acuity and anterior segment were examined using slit lamp biomicroscopy. Results: A total of 390 patients were examined during the study. There were 166 (42.6%) males and 224 (57.4%) females (M:F ratio = 1:1.35). Mean age was 54.81 ± 12.21 years. Seventy-four (18.97%) patients had type I disease, while 316 (81.03%) patients had type II disease. The mean presenting FBS was 9.52 mmol/L ± standard deviation 4.22, with a wide range of 3.4–24.8 mmol/L. Four patients were bilaterally blind, while ten were unilaterally blind from cataract and glaucoma. Myopia and myopic astigmatism were the most observed refractive errors though not statistically associated with high FBS (×2 = 1.00 P = 0.3165). Chronic blepharitis was the main lid finding and found to be related to high FBS (×2 = 38.68 P< 0.000001). Ocular surface findings included pterygia (3.85%), pinguecula (2.56%), dry eyes (2.31%), and combination of these. Bilateral rubeosis iridis and iris atrophy were found in 8 (2.1%) and 6 (1.5%) patients, respectively. Lens opacities varied in location and visual significance. Nuclear sclerosis was the most common lens disorder while posterior subcapsular cataract was the second predominant type observed and was associated with disease duration >10 years (×2 = 11.48, P = 0.0007039). Conclusion: Anterior segment eye disorders in diabetic patients could be clinically significant and yet unreported by the patient. These may cause low vision and blindness similar to nondiabetic population. The screening protocol in the study location should include routine eye examination.
背景:本研究的目的是确定在卡诺Aminu Kano教学医院(AKTH)糖尿病门诊专科诊所就诊的糖尿病患者前段疾病的模式、频率和类型。患者和方法:这是一项为期1年的糖尿病患者AKTH的描述性横断面研究。使用Fisher公式估计样本量,并进行系统抽样以确保符合研究标准的患者的适当随机化。获得的信息包括患者的生物数据、身高、体重、空腹血糖(FBS)、糖尿病类型和病程、相关合并症;采用裂隙灯生物显微镜观察视力及前段。结果:研究期间共检查了390例患者。男性166例(42.6%),女性224例(57.4%)(男女比为1:1.35)。平均年龄54.81±12.21岁。I型74例(18.97%),II型316例(81.03%)。FBS的平均值为9.52 mmol/L±标准差4.22,范围为3.4 ~ 24.8 mmol/L。4例为双侧失明,10例为单侧失明,原因为白内障和青光眼。屈光不正发生率最高的是近视和近视散光,但与高FBS无统计学相关性(×2 = 1.00 P = 0.3165)。慢性眼睑炎是主要的眼睑表现,与高FBS有关(×2 = 38.68 P< 0.000001)。眼表表现包括翼状胬肉(3.85%)、斑疹(2.56%)、眼睛干涩(2.31%)及以上症状的合并。双侧虹膜病变8例(2.1%),虹膜萎缩6例(1.5%)。晶状体混浊的位置和视觉意义各不相同。核硬化是最常见的晶状体疾病,后囊下白内障是第二主要类型,并与病程bbb10年相关(×2 = 11.48, P = 0.0007039)。结论:糖尿病患者前段眼病可能具有临床意义,但未被患者报告。这些可能导致与非糖尿病人群相似的低视力和失明。研究地点的筛查方案应包括常规眼科检查。
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引用次数: 1
Commentary on barriers to the use of modern contraception among married women of high parity in Northern Nigeria 评论尼日利亚北部高胎率已婚妇女使用现代避孕方法的障碍
Pub Date : 2016-07-01 DOI: 10.4103/ARCHMS.ARCHMS_12_17
A. Ajayi
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引用次数: 0
期刊
The Archives of comparative medicine and surgery
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