Advances in colloid and interface science最新文献

Effective delivery of active substances and drugs is an important part of treatment. In order for a drug to work at the right place in the body, it must be transported there in the right way. For this reason, new carriers are being sought for active substances and drugs that can effectively deliver drugs to the target site without causing additional side effects. These include nanoparticles, microneedles, cubosomes and nanogels, among others. Recently, carriers based on biodegradable polymers such as hyaluronic acid or chitosan are becoming popular. In addition, modern carriers are designed to release the active ingredient in response to a specific agent. This paper reviews the literature from the past 5 years on novel delivery systems with medical, agricultural, food and cosmetic applications, with a special emphasis on the use of carbohydrate-based nanocarriers.

Tissue engineering (TE) involves repairing, replacing, regeneration, or improving the function of tissues and organs by combining cells, growth factors and scaffold materials. Among these, scaffold materials play a crucial role. Silk fibroin (SF), a natural biopolymer, has been widely used in the TE field due to its good biodegradability, biocompatibility, and mechanical properties attributed to its chemical composition and structure. This paper reviews the structure, extraction, and modification methods of SF. In addition, it discusses SF's regulation of cell behavior and its various processing modes. Finally, the applications of SF in TE and perspectives on future developments are presented. This review provides comprehensive and alternative rational insights for further biomedical translation in SF medical device design, further revealing the great potential of SF biomaterials.

Microwave absorption materials (MAMs) gradually exhibit crucial applications in reducing electromagnetic wave (EMW) pollution, avoiding EMW information leakage, and solving radar stealth. Metal-organic frameworks (MOFs)-derived materials are flourishing in the domain of EMW absorption attributed to their especial structures, heteroatom doping and controllable components. Herein, various strategies to enhance the EMW absorption ability of MOFs-derived materials are outlined, covering structural design and compositional regulation. Additionally, the applications of MOFs-derived composites in EMW absorption domains are introduced in detail, with emphasis on recent progress in MOFs-derived composites materials like foams, films and aerogels. Finally, existent opportunities, challenges and future orientations of MOFs-derived MAMs are proposed.

Among the many types of surface modifications on porous silicon (pSi), hydrosilylation stands out to be an important approach due to the formation of highly stable surface linkage through Si-C bonding. Since its conceptualization in 1998, hydrosilylation had gradually gained popularity for pSi surface modifications and had become an important approach for stabilizing pSi surfaces especially for biological applications. Over the past decade, significant advancements have been made in the hydrosilylation process for modifying porous silicon (pSi) surfaces. These developments have progressed to the point of enabling the incorporation of multiple chemical functionalities onto a single surface. This review aims to highlight the most recent studies on hydrosilylation of pSi surfaces, explore some of the more unconventional reaction mechanisms available in pSi surface chemistry, and discuss the challenges associated with implementing these strategies.

Nanopore-based electrical detection technology holds single-molecule resolution and combines the advantages of high sensitivity, high throughput, rapid analysis, and label-free detection. It is widely applied in the determination of organic and biological macromolecules, small molecules, and nanomaterials, as well as in nucleic acid and protein sequencing. There are a wide variety of organic polymers and biopolymers, and their chemical structures, and conformation in solution directly affect their ensemble properties. Currently, there is limited approach available for the analysis of single-molecule conformation and self-assembled topologies of polymers, dendrimers and biopolymers. Nanopore single-molecule platform offers unique advantages over other sensing technologies, particularly in molecular size differentiation of macromolecules and complex conformation analysis. In this review, the classification of nanopore devices, including solid-state nanopores (SSNs), biological nanopores, and hybrid nanopores is introduced. The recent developments and applications of nanopore devices are summarized, with a focus on the applications of nanopore platform in the resolution of the structures of synthetic polymer, including dendritic, star-shaped, block copolymers, as well as biopolymers, including polysaccharides, nucleic acids and proteins. The future prospects of nanopore sensing technique are ultimately discussed.

Carbon quantum dots (CQDs) with well-defined architectures offer highly fascinating properties such as excellent water-solubility, exceptional luminescence, large specific surface area, non-toxicity, biocompatibility and tuneable morphological, structural, and chemical features. This review comprehensively overviews recent breakthroughs and critical milestones in the green synthesis of CQDs from renewable sources and provides guidance for their sustainable development towards fulfilling the goals of green chemistry. It also discusses the interaction of CQDs with various biopolymers to improve the material performance and functionality. This paper also highlights the latest technological applications of CQDs in numerous fields, including sustainable packaging, biosensing, bioimaging, cancer therapy, drug delivery as well as water purification. Finally, it summarizes the main challenges and provides an outlook on the future directions of CQDs in packaging and biomedical fields. This review can act as a roadmap to guide researchers for tailoring the properties of CQDs for important composite and biomedical fields.

Nanozyme, a class of emerging enzyme mimics, is the nanomaterials with enzyme-mimicking activity, which has obtained significant and widespread applications in various fields. However, they still face many challenges in practical applications (e.g., instability and low biocompatibility in the physiological environments), which affect their widespread applications to a certain extent. Hydrogels with superior performances (e.g., the controllable degradability, good biocompatibility, hydrophilic properties, and adjustable physical properties) may provide a promising strategy to make up the existing deficiencies of nanozymes in practical applications. Thus, the sapiential combination of nanozymes with hydrogels endows nanozyme hydrogels with both characteristics of nanozymes and properties of hydrogels, making nanozyme hydrogels become novel multifunctional materials. In this review, we comprehensively summarizes the preparation, properties, and progressive applications of nanozyme hydrogels. First of all, the main design and preparation strategies of nanozyme hydrogels are considerately summarized. Then, the properties of different nanozyme hydrogels are introduced. In addition, sophisticated applications of nanozyme hydrogels in the fields of biosensing, biomedicine applications, and environmental are comprehensively summarized. Most importantly, future obstacles and chances in this emerging field are profoundly proposed. This review will provide a new horizon for the development and future applications of novel nanozyme hydrogels.

Rare earth elements (REEs) are crucial metallic resources that play an essential role in national economies and industrial production. The reclaimation of REEs from wastewater stands as a significant supplementary strategy to bolster the REEs supply. Adsorption techniques are widely recognized as environmentally friendly and sustainable methods for the separation of REEs from wastewater. Despite the growing interest in adsorption-based REEs separation, comprehensive reviews of both traditional and novel adsorbents toward REEs recovery remain limited. This review aims to provide a thorough analysis of various adsorbents for the recovery of REEs. The types of adsorbents examined include activated carbons, functionalized silica nanoparticles, and microbial synthetic adsorbents, with a detailed evaluation of their adsorption capacities, selectivity, and regeneration potential. This study focuses on the mechanisms of REEs adsorption, including electrostatic interactions, ion exchange, surface complexation, and surface precipitation, highlighting how surface modifications can enhance REEs recovery efficiency. Future efforts in designing high-performance adsorbents should prioritize the optimization of the density of functional groups to enhance both selectivity and adsorption capacity, while also maintaining a balance between overall capacity, cost, and reusability. The incorporation of covalently bonded functional groups onto mechanically robust adsorbents can significantly strengthen chemical interactions with REEs and improve the structural stability of the adsorbents during reuse. Additionally, the development of materials with high specific surface areas and well-defined porous structures is benifitial to facilitating mass transfer of REEs and maximizing adsorption efficiency. Ultimately, the advancement of the design of efficient, highly selective and recyclable adsorbents is critical for addressing the growing demand for REEs across diverse industrial applications.

The glycocalyx and its associated endothelial surface layer which lines all cell membranes and most tissues, dwarfs the phospholipid membrane of cells in extent. Its major components are sulphated polymers like heparan and chondroitin sulphates and hyaluronic acid. These form a fuzzy layer of unknown structure and function. It has become increasingly clear that the ESL-GC complex must play many roles. We postulate it has a self-organised infrastructure that directs cell traffic, acts in defence against pathogens and other cells, and in diseases like diabetes, and heart disease, besides being a playground for a host of biochemical activity. Based on an analogous sulphated polymeric system Nafion, the fuel cell polymer, we suggest a model for the structure of the ESL-GC complex and how it functions. Taken together with parallel developments in physical chemistry, in nanobubbles, their stability in physiological media, and reactivity, we believe the model may throw light on a variety of phenomena, diabetes and some other diseases.

In the evolving landscape of nanotechnology and pharmaceuticals, lipid nanostructures have emerged as pivotal areas of research due to their unique ability to mimic biological membranes and encapsulate active molecules. These nanostructures offer promising avenues for drug delivery, vaccine development, and diagnostic applications. This comprehensive review explores the complex mechanisms underlying the formation and stability of various lipid nanostructures, including lipid liquid crystalline nanoparticles and solid lipid nanoparticles. Drawing upon a wide array of studies, we integrate current knowledge on the physicochemical properties of lipids that contribute to nanostructure formation, such as lipid composition, charge, and the role of environmental factors such as pH and ionic strength. We further discuss the stabilisation mechanisms that preserve the integrity and functionality of these nanostructures in biological systems, highlighting the influence of surface modification, PEGylation, and the incorporation of stabilising agents. Through a methodical examination of both classical theories and cutting-edge research, our review highlights the critical factors that dictate the self-assembly of lipids into nanostructures, the dynamics of their formation, and the interplay between different stabilising forces. The implications of these insights for the design of lipid-based delivery systems are vast, offering the potential to enhance the bioavailability of therapeutics, target specific tissues or cells, and minimise adverse effects. The integration of lipid nanostructures in pharmaceutical nanotechnology not only stands to revolutionise the delivery of therapeutic agents but also paves the way for innovative applications in targeted therapy, personalised medicine, and vaccine adjuvant development. By bridging the gap between fundamental biophysical studies and applied research, this review contributes to the ongoing discourse on lipid nanostructures, advocating for a multidisciplinary approach to harness their full potential.