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Hepatectomy During the Pandemic, a Curative Treatment in High-Grade and/or Hemodynamically Unstable Blunt Liver Trauma. 大流行病期间的肝切除术,对高级别和/或血液动力学不稳定的钝性肝损伤的治疗。
Pub Date : 2023-01-01 Epub Date: 2023-03-31 DOI: 10.12865/CHSJ.49.01.123
Gheorghe-Jean Boldea, Eugen Florin Georgescu, Ion Georgescu, Dumitru Rădulescu, Mircea Pîrșcoveanu

The liver is among the most affected organs in the case of abdominal trauma. In the last decades there have been significant changes in therapeutic protocols, non-operative management is now the first intention in most cases due to good results offered previously. In high-grade or hemodynamically unstable injuries, hepatectomy is the best approach, even though this was viewed with skepticism in the past, technical advances in medicine have proven otherwise. This article presents a case report of a 29-year-old man with blunt abdominal trauma, who initially underwent conservative atypical right hepatectomy without a favourable outcome, later he was transferred to a liver transplant center where he underwent a controlled right hepatectomy, all this in a new epidemiological context, the COVID-19 Pandemic. We want to present the hypothesis that in making a therapeutic decision, the hemodynamic status of the patient must be considered equally along with the injury degree. This case represents an opportunity to review the role of liver resection in the management of complex liver injuries.

在腹部创伤的情况下,肝脏是受影响最严重的器官之一。在过去的几十年里,治疗方案发生了重大变化,由于之前提供的良好结果,非手术治疗现在是大多数情况下的首选。在高级别或血液动力学不稳定的损伤中,肝切除术是最好的方法,尽管过去人们对此持怀疑态度,但医学的技术进步已经证明并非如此。本文报告了一名29岁男子的病例报告,他患有钝性腹部创伤,最初接受了保守的非典型右肝切除术,但没有良好的结果,后来被转移到肝脏移植中心,在那里他接受了控制性右肝切除手术,所有这一切都是在新的流行病学背景下进行的,即新冠肺炎大流行。我们想提出这样一个假设,即在做出治疗决定时,患者的血液动力学状态必须与损伤程度同等考虑。本病例为回顾肝切除术在复杂肝损伤治疗中的作用提供了机会。
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引用次数: 0
Management and Treatment of Coxarthrosis in the Orthopedic Outpatient Clinic. 骨科门诊治疗Coxarthasis的管理与治疗。
Pub Date : 2023-01-01 Epub Date: 2023-03-31 DOI: 10.12865/CHSJ.49.01.102
Anton Tiberiu Paraliov, Monica Mihaela Iacov-Craitoiu, Mariana Mădălina Mogoantă, Octavian Ion Predescu, Laurențiu Mogoantă, Ștefania Crăiţoiu

Coxarthrosis, or hip osteoarthritis (OA), is one of the main causes of hip pain, which can affect patients of all ages, being one of the most common reasons for patients presenting to the specialized outpatient clinic. The objective of our research was to determine the number of patients with coxarthrosis who presented to the Department of Orthopaedics and Traumatology within the Emergency County Hospital of Drobeta Turnu Severin, between 2017-2019, the sex, age, social environment of the patients. All patients underwent a thorough clinical examination to determine the risk factors, the favouring factors and their correlation with the paraclinical data obtained through imaging investigation (pelvis X-ray, computer tomography and nuclear magnetic resonance). The study included 462 patients, aged between 23 and 89 years old, who were diagnosed with varying degrees of coxarthrosis within the specialized outpatient clinic. The main risk factors were obesity, osteoporosis, chronic smoking, rural environment, female sex, the existence of a hip injury and intense physical exertion. The main purpose of the research was to analyse a series of data, which would bring information on the incidence, distribution by age groups, sex, living environment and professional activity of the population with coxarthrosis, in order to develop a therapeutic management as effective as possible.

髋关节炎或髋关节骨性关节炎(OA)是髋关节疼痛的主要原因之一,它可以影响所有年龄段的患者,也是患者到专科门诊就诊的最常见原因之一。我们研究的目的是确定2017-2019年间,Drobeta Turnu Severin县急诊医院骨科和创伤科就诊的髋关节病患者人数,以及患者的性别、年龄和社会环境。所有患者都接受了彻底的临床检查,以确定风险因素、有利因素及其与通过影像学研究(骨盆X射线、计算机断层扫描和核磁共振)获得的临床旁数据的相关性。该研究包括462名患者,年龄在23岁至89岁之间,他们在专科门诊被诊断为不同程度的髋关节病。主要危险因素是肥胖、骨质疏松、长期吸烟、农村环境、女性、髋关节损伤和剧烈体力劳动。该研究的主要目的是分析一系列数据,这些数据将提供有关髋关节病患者的发病率、年龄组分布、性别、生活环境和职业活动的信息,以制定尽可能有效的治疗方法。
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引用次数: 0
An L2/3 Disc Herniation-Related L5 Radiculopathy. 一种与L2/3椎间盘突出相关的L5根性病变。
Pub Date : 2023-01-01 Epub Date: 2023-03-31 DOI: 10.12865/CHSJ.49.01.129
Eric Chun-Pu Chu, Kristy Hoi-Ying Yau, David Lawrence Bellin

The key factors contributing to radiculopathy caused by lumbar disc herniation include mechanical compression. It was commonly believed that the disc herniation causes the compression on the nerve root exiting under the pedicle of the vertebral body at the adjacent inferior level. However, a disc herniation might occasionally result in non-adjacent, isolated radicular symptoms. We report the case of a 74-year-old female who presented with a 2-years history of progressive low back pain associated with L5 radiculopathy and reduced quality of life. The patient had undergone a magnetic resonance image showing a large L2/3 disc herniation. Symptoms had progressively worsened and failed to respond to conservative treatments including pain medication, exercise rehabilitation, and acupuncture at the lower lumbar region. The patient was diagnosed with L5 radiculopathy caused by L2/3 disc herniation. Consequently, her symptoms improved with chiropractic rehabilitation which involved spinal manipulative therapy and intermittent motorized traction at the L2/3 level to reduce herniated disc. Therefore, an L2/3 Disc herniation-related L5 radiculopathy should be considered in the differential diagnosis of cases of inconsistency of level of disc herniation and nerve root pattern.

导致腰椎间盘突出引起神经根病的关键因素包括机械压迫。人们普遍认为,椎间盘突出会压迫邻近下段椎体椎弓根下的神经根。然而,椎间盘突出症偶尔可能会导致非相邻的、孤立的神经根症状。我们报告了一例74岁的女性病例,她有2年的进行性腰痛史,伴有L5神经根病和生活质量下降。患者接受了磁共振成像,显示大的L2/3椎间盘突出。症状逐渐恶化,对包括止痛药、运动康复和下腰部针灸在内的保守治疗无效。该患者被诊断为由L2/3椎间盘突出引起的L5神经根病。因此,她的症状通过脊椎按摩康复得到改善,该康复包括脊椎手法治疗和L2/3水平的间歇性电动牵引,以减少椎间盘突出。因此,在椎间盘突出程度和神经根模式不一致的病例的鉴别诊断中,应考虑与L2/3椎间盘突出相关的L5神经根病。
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引用次数: 2
Vertebral Artery Dissection: A Case Report and Review of the Literature. 椎动脉夹层:一例报告并文献复习。
Pub Date : 2023-01-01 Epub Date: 2023-03-31 DOI: 10.12865/CHSJ.49.01.115
Oana-Andreea Dogariu, Ioan Dogariu, Mihaela Berceanu, Raluca Sandu, Ioana Andreea Gheonea

Arterial dissection is the result of blood entering along the intima-media plane through a breach produced either spontaneously or traumatically. Cervical arterial dissections are an important cause of acute ischemic stroke in children, young adults, and patients with cranio-cervical traumatic injuries. Arterial dissections occur either spontaneously, in genetic diseases, the most important association being with fibromuscular dysplasia. In most of the cases dissection involve the extracranial portions of the internal carotid and vertebral arteries. Magnetic resonance with T1 fat-saturation (T1 FS) sequence of the cervical region or computed tomography (CT) with computed tomography angiography (CTA) shows a very high sensitivity and specificity in the diagnosis of cervical artery dissections. Therapeutic options are still debatable in patients with acute ischemic stroke and vertebral or carotid artery dissection.

动脉夹层是血液通过自发或创伤产生的破裂沿内膜-中层平面进入的结果。颈动脉夹层是儿童、年轻人和颅颈创伤患者急性缺血性卒中的重要原因。动脉夹层在遗传性疾病中自发发生,最重要的是与纤维肌发育不良有关。在大多数情况下,夹层涉及颈内动脉和椎动脉的颅外部分。颈部T1脂肪饱和(T1FS)序列的磁共振或计算机断层扫描(CT)与计算机断层扫描血管造影术(CTA)在诊断颈动脉夹层方面显示出非常高的敏感性和特异性。急性缺血性中风和椎动脉或颈动脉夹层患者的治疗方案仍有争议。
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引用次数: 0
A Review Regarding the Connections between Allergic Rhinitis and Asthma - Epidemiology, Diagnosis and Treatment. 过敏性鼻炎与哮喘的关系综述——流行病学、诊断和治疗。
Pub Date : 2023-01-01 Epub Date: 2023-03-31 DOI: 10.12865/CHSJ.49.01.5
Andreea Iordache, Nicolae Constantin Balica, Ioana Delia Horhat, Raluca Morar, Alina Andreea Tischer, Adina Iuliana Milcu, Mădălina Casiana Salavat, Veronica Mădălina Borugă

Allergic rhinitis is characterized by an acute or chronic inflammation of the nasal mucosa, being frequently associated with other airway conditions such as sinusitis, serous otitis media, nasal polyposis, sleep disorders and asthma in particular. Among the comorbidities of allergic rhinitis it counts asthma, being a risk factor for this disorder, in which, more than 75% of patients develop asthma (either allergic or nonallergic), whereas the patients with allergic rhinitis can be affected up to 40% by asthma. The classic symptoms for allergic rhinitis involves sneezing, nasal mucosal swelling and watery rhinorrhea; whereas the main symptoms which occurred in patients with asthma are wheezing, breathlessness, chest tightness, coughing, fast heartbeat, confusion, exhaustion or dizziness. Avoiding allergens is the first line of treatment for allergic rhinitis, followed by medication and allergen immunotherapy. Due to the strong connection between allergic rhinitis and asthma, one can affirm that the treatment for allergic rhinitis lead to the improvement of asthma symptoms. One can diagnose asthma by recognizing a certain pattern of respiratory symptoms and expiratory airflow restriction, which varies for each patient. In conclusion, accurate identification of the differences between allergic rhinitis and asthma depends on a thorough history, physical examination, and therapeutic treatments. This article provides an overview of the connection between these disorders, as well as of the diagnosis of these conditions and their current management options.

过敏性鼻炎的特征是鼻粘膜的急性或慢性炎症,通常与其他气道疾病有关,如鼻窦炎、浆液性中耳炎、鼻息肉病、睡眠障碍和哮喘。在过敏性鼻炎的合并症中,哮喘是这种疾病的一个危险因素,其中超过75%的患者发展为哮喘(过敏性或非过敏性),而过敏性鼻炎患者可能会受到高达40%的哮喘影响。过敏性鼻炎的典型症状包括打喷嚏、鼻粘膜肿胀和流鼻涕;而哮喘患者的主要症状是喘息、呼吸困难、胸闷、咳嗽、心跳加快、意识模糊、疲惫或头晕。避免过敏原是治疗过敏性鼻炎的第一道防线,其次是药物治疗和过敏原免疫治疗。由于过敏性鼻炎和哮喘之间有着密切的联系,可以肯定的是,治疗过敏性鼻炎可以改善哮喘症状。人们可以通过识别特定的呼吸症状模式和呼气气流受限来诊断哮喘,这些症状因患者而异。总之,准确识别过敏性鼻炎和哮喘之间的差异取决于彻底的病史、体检和治疗。本文概述了这些疾病之间的联系,以及这些疾病的诊断和目前的管理选择。
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引用次数: 0
Evaluation of Early Repolarization Pattern in Children with Mitral Valve Prolapse. 评估二尖瓣脱垂儿童的早期再极化模式
Pub Date : 2023-01-01 Epub Date: 2023-03-31 DOI: 10.12865/CHSJ.49.01.67
Mojtaba Akhavan Palangsarai, Mahya Mobinikhaledi, Elham Farahani, Fatemeh Dorreh, Parsa Yousofichaijan, Yazdan Ghandi

Background: Patients with mitral valve prolapse (MVP) may be prone to ventricular arrhythmias and sudden cardiac death and presence early repolarization pattern (ERP) in electrocardiography may be predict for ventricle arrhythmia. This study aimed to evaluation ERP in Children with MVP.

Methods: In a cross-sectional study, we enrolled ERP in 70 MVP children with 70 age-and sex-matched healthy individuals. After echocardiography procedure for confirmation MVP, standard 12-lead electrocardiography recordings with sweeping rate of 25mm/s and an amplitude of 10mV/cm, and two cardiologists assessed who were blinded to the both groups.

Result: We detected ERP in 17.14% of MVP patient's and seen in 8 case (11.43%) in control group, (P=0.23). the ERP occurred in MVP patient's mild, moderate and severe 4, 6 and 2 cases, (P=0.29). The ERP found in patients with and without chest pain 13 and 7, respectively (P=0.46) and, in patients with and without palpitations 15 and 5 cases, respectively (P=0.24). The ERP occurred 1.6 time more in patient with MVP in comparing with individual without MVP. The ERP occurred more frequently in among patients with moderate MVP in comparing with severe and mild. Chest pain and palpitation occurred more frequently in among patients with severe MVP.

Conclusion: The prevalence of ERP in children with MVP has been at a higher-level incidence, especially among patients with complaining from chest pain. We suggested that children with MVP are in need of follow up considering the occurrence of arrhythmias.

背景:二尖瓣脱垂(MVP)患者容易发生室性心律失常和心脏性猝死,而心电图中出现的早期再极化模式(ERP)可能是室性心律失常的预兆。本研究旨在评估 MVP 儿童的ERP:在一项横断面研究中,我们对 70 名 MVP 儿童和 70 名年龄与性别匹配的健康人进行了ERP 评估。在超声心动图检查确诊 MVP 后,进行标准的 12 导联心电图记录,扫描频率为 25mm/s,振幅为 10mV/cm,由两名心脏病专家进行评估,这两名专家对两组患者都是盲人:我们在 17.14% 的 MVP 患者中发现了 ERP,在对照组中发现了 8 例(11.43%),(P=0.23)。MVP 患者中,轻度、中度和重度分别为 4 例、6 例和 2 例,(P=0.29)。在有胸痛和无胸痛的患者中,ERP 分别为 13 例和 7 例(P=0.46);在有心悸和无心悸的患者中,ERP 分别为 15 例和 5 例(P=0.24)。与没有 MVP 的患者相比,MVP 患者的 ERP 发生率高 1.6 倍。与重度和轻度 MVP 患者相比,中度 MVP 患者发生 ERP 的频率更高。结论:结论:ERP 在 MVP 儿童中的发病率较高,尤其是在主诉胸痛的患者中。我们建议,考虑到心律失常的发生,MVP 儿童需要进行随访。
{"title":"Evaluation of Early Repolarization Pattern in Children with Mitral Valve Prolapse.","authors":"Mojtaba Akhavan Palangsarai, Mahya Mobinikhaledi, Elham Farahani, Fatemeh Dorreh, Parsa Yousofichaijan, Yazdan Ghandi","doi":"10.12865/CHSJ.49.01.67","DOIUrl":"https://doi.org/10.12865/CHSJ.49.01.67","url":null,"abstract":"<p><strong>Background: </strong>Patients with mitral valve prolapse (MVP) may be prone to ventricular arrhythmias and sudden cardiac death and presence early repolarization pattern (ERP) in electrocardiography may be predict for ventricle arrhythmia. This study aimed to evaluation ERP in Children with MVP.</p><p><strong>Methods: </strong>In a cross-sectional study, we enrolled ERP in 70 MVP children with 70 age-and sex-matched healthy individuals. After echocardiography procedure for confirmation MVP, standard 12-lead electrocardiography recordings with sweeping rate of 25mm/s and an amplitude of 10mV/cm, and two cardiologists assessed who were blinded to the both groups.</p><p><strong>Result: </strong>We detected ERP in 17.14% of MVP patient's and seen in 8 case (11.43%) in control group, (P=0.23). the ERP occurred in MVP patient's mild, moderate and severe 4, 6 and 2 cases, (P=0.29). The ERP found in patients with and without chest pain 13 and 7, respectively (P=0.46) and, in patients with and without palpitations 15 and 5 cases, respectively (P=0.24). The ERP occurred 1.6 time more in patient with MVP in comparing with individual without MVP. The ERP occurred more frequently in among patients with moderate MVP in comparing with severe and mild. Chest pain and palpitation occurred more frequently in among patients with severe MVP.</p><p><strong>Conclusion: </strong>The prevalence of ERP in children with MVP has been at a higher-level incidence, especially among patients with complaining from chest pain. We suggested that children with MVP are in need of follow up considering the occurrence of arrhythmias.</p>","PeriodicalId":93963,"journal":{"name":"Current health sciences journal","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10832877/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139674039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Influence of Covid-19 Infection on Neurocognitive Disorders 新冠肺炎感染对神经认知障碍的影响
Pub Date : 2021-12-31 DOI: 10.12865/CHSJ.47.04.17
Daniela-Gabriela Glavan, V. Gheorman, M. Aldea, F. Militaru, I. Udriștoiu
Neurocognitive disorders are a group of disorders characterized by an impaired cognition which has not been present since birth or very early life and represents a decline from a previous attained level of functioning. The case we studied is M.E., a 62 years female, married, from rural area, working as a tailor, without any psychiatric history. She develops psychiatric symptoms during Covid-19 infection and treatment, in November 2020. The patient has been admitted in psychiatric care, in that time, for about one month, for a persistent confusion state during and after this event. These symptoms diminish the patient's level of functioning and seemed to be related with the Covid-19 infection or treatment. Psychological investigation underlines a MMSE 14, severe impairment in attention, short-term and long-term memory. CT evaluation presents normal relation except a moderate general atrophy, according with patient’s age. Differential diagnosis will be discussed. The treatment has proven its effectiveness, the patient regaining her ability to orientate, could do housework, good improvement in attention and short-term memory. We emphasize that there is correlation between the Covid-19 infection and confusive state and delirium in patients, as a comorbidity, followed in many cases by chronic progressive neurocognitive disorder, especially in elderly.
神经认知障碍是一组以认知受损为特征的障碍,自出生或很早的时候就没有出现过,表现为与以前达到的功能水平相比有所下降。我们研究的病例是M.E.,一名62岁的女性,已婚,来自农村,做裁缝,没有任何精神病史。2020年11月,她在新冠肺炎感染和治疗期间出现精神症状。在这段时间里,患者因在事件发生期间和之后持续的困惑状态而被送入精神病院约一个月。这些症状降低了患者的功能水平,似乎与新冠肺炎感染或治疗有关。心理调查强调MMSE 14,注意力、短期和长期记忆严重受损。根据患者的年龄,CT评估显示除中度全身萎缩外,其他关系正常。将讨论鉴别诊断。该治疗已被证明是有效的,患者恢复了定向能力,可以做家务,注意力和短期记忆有很好的改善。我们强调,新冠肺炎感染与患者的困惑状态和谵妄之间存在相关性,这是一种合并症,在许多情况下,随后是慢性进行性神经认知障碍,尤其是老年人。
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引用次数: 0
Variation of Total Antioxidant Activity in Young People with Non-Lesional Cardiac Arrhythmias 青年非损伤性心律失常患者总抗氧化活性的变化
Pub Date : 2021-12-31 DOI: 10.12865/CHSJ.47.04.12
M. Beznă, C. Pisoschi, M. Beznă, S. Dănoiu, C. Negroiu, P. R. Melinte
Total antioxidant activity status (TAS) represents the body's response to oxidative stress, important in the pathogenic assessment of oxidations. Aim: To determine TAS variations in young subjects, with non-lesional cardiac arrhythmias, with/without dyslipidemia and to assess the risk of lipid oxidation. Patients and methods: The research was performed on 120 young subjects (mean age 33 years), with various types of cardiac arrhythmias, on normal heart, without co-existing lesions. Subjects were divided into 3 groups (40 persons). The first 2 groups included subjects with cardiac arrhythmias. Group I also associated dyslipidemia; group II, without dyslipidemia and group III: control. Determination of TAS values was performed using ABTS (2-azino-di-3-ethylbenzthiazoline sulfonate) colorimetic method. Results were statistically processed. Results: TAS values were decreased in all patients with cardiac arrhythmias, representing 52-54% of the values of healthy controls, the data being highly statistically significant. The variation of TAS decrease by types of arrhythmias was thus found in patients with arrhythmias and associated dyslipidemia and, respectively, without dyslipidemia, compared to controls. The deficit of antioxidant activity, between 48%-46% triggers electrochemical processes with implications in arrhythmogenesis and lipid oxidation. Coffee and vegetables-rich diet have antioxidant effect, reducing TAS deficiency. Conclusions: 1. TAS was decreased in all subjects with non-lesional arrhythmias. The study showed decreasing TAS level at 52-54% in patients with arrhythmias, with/without dyslipidemia, compared to controls. 2. TAS deficiency was associated with various types of dysrhythmias, ranging from 62% to 33%. 3. Decreased TAS also triggers lipid oxidation, as risk factor for early atherosclerotic lesions.
总抗氧化活性状态(TAS)代表身体对氧化应激的反应,在氧化的致病性评估中很重要。目的:确定患有非病变性心律失常、伴有/不伴有血脂异常的年轻受试者的TAS变化,并评估脂质氧化的风险。患者和方法:研究对象为120名年轻受试者(平均年龄33岁),他们患有各种类型的心律失常,心脏正常,无共存病变。受试者被分为3组(40人)。前2组包括心律失常的受试者。I组还伴有血脂异常;第二组:无血脂异常,第三组:对照组。TAS值的测定使用ABTS(2-锌基二-3-乙基苯并噻唑啉磺酸盐)比色法进行。对结果进行统计处理。结果:所有心律失常患者的TAS值均下降,占健康对照组的52-54%,数据具有高度统计学意义。因此,与对照组相比,在有心律失常和相关血脂异常的患者和没有血脂异常的病人中,发现TAS降低随心律失常类型的变化。抗氧化活性的缺乏,在48%-46%之间触发电化学过程,与心律失常和脂质氧化有关。富含咖啡和蔬菜的饮食具有抗氧化作用,减少TAS缺乏。结论:1。所有非病变性心律失常受试者的TAS均降低。研究表明,与对照组相比,心律失常伴/不伴血脂异常的患者的TAS水平降低了52-54%。2.TAS缺乏与各种类型的心律失常有关,从62%到33%不等。3.TAS降低也会触发脂质氧化,这是早期动脉粥样硬化病变的危险因素。
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引用次数: 1
Knowledge and Willingness to Accept Vaccine Against SARS-CoV-2 Among Undergraduate Medical Students in Delhi, India 印度德里医科大学生接受严重急性呼吸系统综合征冠状病毒2型疫苗的知识和意愿
Pub Date : 2021-12-31 DOI: 10.12865/CHSJ.47.04.01
A. K. Shah, R. Daniel, Y. Kusuma
Vaccination against severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the most desired solution to combat COVID-19. Understanding the willingness to accept vaccines is essential to make appropriate strategies for the vaccination programme's success. There was a lack of published literature in India among medical students. Hence, we conducted this online, cross-sectional study to assess the knowledge and willingness to accept COVID-19 vaccines among undergraduate medical students of a medical school in Delhi. A complete enumeration of all the undergraduate medical students was done. All the students were invited to participate in this online survey. The questionnaire through Google forms was shared through email and WhatsApp. The questionnaire contained questions on the socio-demographic details, questions related to the knowledge and perceptions about COVID-19 vaccines, willingness to accept the vaccine and vaccination status of the participant. Descriptive and multiple logistic regression analyses were carried out. Out of 320 students contacted, 298 consented to participate in the survey, and 274 participants (85%) completed the questionnaire. Three-fourths of the participants were male; the mean age of the study participants was 19.6 years. Only 70.4% were willing to accept the vaccine. Those who perceived COVID-19 vaccines as safe (AOR=3.946; 95% CI: 1.946 to 7.912); and effective (AOR=2.079; 95% CI: 1.054 to 4.101); and who has knowledge about the vaccines (AOR=2.206; 95% CI: 1.186 to 4.104) were more likely to accept the vaccine. There is a need for enhancing the knowledge on vaccines, and their safety and effectiveness to promote the vaccine acceptance.
针对严重急性呼吸综合征冠状病毒-2 (SARS-CoV-2)的疫苗接种是抗击COVID-19最理想的解决方案。了解接受疫苗的意愿对于制定疫苗接种规划成功的适当战略至关重要。在印度,医科学生中缺乏已发表的文献。因此,我们进行了这项在线横断面研究,以评估德里一所医学院本科医学生对COVID-19疫苗的知识和接受意愿。对所有医科本科生进行了一次完整的清点。所有的学生都被邀请参加这个在线调查。通过谷歌表格的问卷通过电子邮件和WhatsApp分享。问卷内容包括社会人口学细节、对COVID-19疫苗的知识和认知、接受疫苗的意愿和接种情况等问题。进行了描述性和多元逻辑回归分析。在联系的320名学生中,298名同意参与调查,274名参与者(85%)完成了问卷调查。四分之三的参与者是男性;研究参与者的平均年龄为19.6岁。只有70.4%的人愿意接受疫苗。认为COVID-19疫苗安全的人(AOR=3.946;95% CI: 1.946 ~ 7.912);有效(AOR=2.079;95% CI: 1.054 ~ 4.101);对疫苗了解程度(AOR=2.206;95% CI: 1.186 ~ 4.104)更有可能接受疫苗。有必要加强对疫苗及其安全性和有效性的认识,以促进疫苗的接受。
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引用次数: 4
Vulvar Verrucous Carcinoma and Genital Condylomatosis 外阴疣状癌与生殖器尖锐湿疣病
Pub Date : 2021-12-31 DOI: 10.12865/CHSJ.47.04.19
A. Vîlcea, L. Stoica, N. Cernea, M. Marinaș, Tiberiu-Ștefăniță Țenea-Cojan
Verrucous carcinoma is a histopathological type of well-differentiated squamous cell carcinoma, clinically characterized by slow and continuous growth, having a local destructive character, but low metastasis potential. Condyloma acuminatum is a sexually transmitted infection caused mainly by subtypes 6 and 11 of HPV, with subtypes 16, 18 being involved in malignant transformation. We present the case of a 70-year-old woman, hospitalized for a vulvar and perineal vegetative, ulcerated, bleeding tumor, with onset 20 years ago. The therapeutic option was surgical excision of the lesions and long-term oncological monitoring.
疣状癌是一种组织病理学类型的高分化鳞状细胞癌,临床特征为缓慢而持续的生长,具有局部破坏性,但转移潜力低。尖锐湿疣是一种主要由HPV亚型6和11引起的性传播感染,其中亚型16、18参与了恶性转化。我们提出的情况下,一个70岁的妇女,住院外阴和会阴植物性,溃疡,出血肿瘤,与20年前发病。治疗选择是手术切除病变和长期肿瘤监测。
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引用次数: 1
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