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Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology最新文献

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Oral health-related quality of life status and risk factors in patients with mental disorders. 精神障碍患者口腔健康相关生活质量状况及危险因素分析
Xuemei Yang, Hongyu Wang, Yonghua Tang, Chengjun Yin, Jingya Yu, Xiaoqin Bi

Objectives: This study aims to explore the current status and risk factors of oral health-related quality of life OHRQoL in patients with mental disorders and provide evidence for effective intervention measures.

Methods: A total of 397 patients diagnosed with mental illness were selected by convenience sampling, and investigation was carried out using general data questionnaire, health literacy in dentistry-14 (HeLD-14), oral health impact profile-14 (OHIP-14), and oral health status checklist.

Results: The total score of OHIP-14 in patients with mental disorders was 8(2, 14). The score of HeLD-14 was negatively correlated with the score of OHIP-14 (r=-0.142, P<0.01). The results of multiple linear regression showed that six variables including annual family income, schizophrenia, sweets, frequency of visits to the dentist, dental caries, and missing teeth affected OHRQoL of patients with mental disorders (P<0.05).

Conclusions: The poor OHRQoL of psychiatric patients is associated with many factors. Medical personnel should pay attention to their oral health problems and develop targeted oral care programs throughout the course of disease to improve oral health and related quality of life of patients.

目的:探讨精神障碍患者口腔健康相关生活质量OHRQoL的现状及危险因素,为制定有效的干预措施提供依据。方法:采用方便抽样的方法,抽取397例确诊为精神疾病的患者,采用一般资料问卷、口腔健康素养问卷-14 (HeLD-14)、口腔健康影响问卷-14 (OHIP-14)和口腔健康状况调查表进行调查。结果:精神障碍患者OHIP-14总分为8分(2,14)。HeLD-14得分与OHIP-14得分呈负相关(r=-0.142, ppp)。结论:精神科患者OHRQoL较差与多种因素有关。医护人员应关注患者的口腔健康问题,并在整个疾病过程中制定有针对性的口腔护理方案,以改善患者的口腔健康和相关的生活质量。
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引用次数: 0
Bioactive glass 45S5 promotes odontogenic differentiation of apical papilla cells through autophagy. 生物活性玻璃45S5通过自噬促进根尖乳头细胞成牙性分化。
Weilin Liu, Can Su, Caiyun Cui
<p><strong>Objectives: </strong>The mechanism of the odontogenic differentiation of apical papillary cells (APCs) stimulated by bioactive glass 45S5 is still unclear. This study aims to investigate the effect of autophagy on the odontogenic differentiation of APCs stimulated by bioactive glass 45S5.</p><p><strong>Methods: </strong>APCs were isolated and cultured <i>in vitro</i>, and the cell origin was identified by flow cytometry. The culture medium was prepared with 1 mg/mL 45S5, and its pH and ion concentration were determined. The experiments were divided into control, 45S5, and 3-methyladenine (3-MA) 45S5 groups. In the 45S5 group, APCs were induced to culture with 1 mg/mL 45S5. In the 3-MA 45S5 group, the autophagy inhibitor 3-MA was added to 1 mg/mL 45S5. Protein immunoblotting assay (Western blot) was used to detect the expression of autophagy-associated proteins of microtubule-associated protein 1 light-chain 3β (LC3B) and P62 after 24 h of induction culture in each group. Real-time quantitative polymerase chain reaction (RT-qPCR) was used to detect the expression of bone sialoprotein (BSP), Runt-related transcription factor 2 (Runx2), dentin sialophosphoprotein (DSPP), and dentin matrix protein-1 (DMP-1) after 7 d of induction culture. Cellular alkaline phosphatase (ALP) staining analyzed cellular ALP activity at 7 d of induction, and alizarin red staining evaluated the formation of mineralized nodules at 21 d of induction.</p><p><strong>Results: </strong>The pH of the 45S5 extract culture medium was 8.65±0.01, which was not significantly different from that of the control group (<i>P</i>>0.05). The silicon ion concentration of the 45S5 induction culture medium was (1.56±0.07) mmol/L, which was higher than that of the control group (0.08±0.01) mmol/L (<i>P</i><0.05). The calcium ion concentration of the 45S5 induction culture was (1.57±0.15) mmol/L, which was not significantly different from that of the control group (<i>P</i>>0.05). Western blot results showed that LC3B-Ⅱ/Ⅰ ratio increased and P62 expression decreased in the 45S5 group compared with those in the control group (<i>P</i><0.05). By contrast, the ratio decreased and the expression increased in the 3-MA 45S5 group compared with those in the 45S5 group (<i>P</i><0.05). RT-qPCR results showed that the expression of BSP, Runx2, DMP-1, and DSPP enhanced in the 45S5 group compared with that in the control group (<i>P</i><0.05), but the expression decreased in the 3-MA 45S5 group compared with that in the 45S5 group (<i>P</i><0.05). Semi-quantitative analysis of ALP staining and alizarin red staining showed that the ALP activity was enhanced, and the formation mineralized nodule increased in the 45S5 group compared with those in the control group. The ALP activity weakened, and the formation mineralized nodules were reduced in the 3-MA 45S5 group compared with that those in the 45S5 group.</p><p><strong>Conclusions: </strong>Cell autophagy participates in the odontogenic differen
目的:生物活性玻璃45S5刺激尖乳头细胞(APCs)成牙分化的机制尚不清楚。本研究旨在探讨自噬对生物活性玻璃45S5刺激APCs成牙分化的影响。方法:体外分离培养APCs,流式细胞术鉴定细胞来源。以1 mg/mL 45S5配制培养基,测定其pH和离子浓度。实验分为对照组、45S5组和3-甲基腺嘌呤(3-MA) 45S5组。45S5组以1 mg/mL 45S5诱导APCs培养。在3-MA 45S5组,自噬抑制剂3-MA加入到1 mg/mL 45S5中。蛋白免疫印迹法(Western blot)检测各组诱导培养24 h后自噬相关蛋白微管相关蛋白1轻链3β (LC3B)和P62的表达情况。采用实时定量聚合酶链反应(RT-qPCR)检测诱导培养7 d后骨唾液蛋白(BSP)、runt相关转录因子2 (Runx2)、牙本质唾液磷蛋白(DSPP)、牙本质基质蛋白-1 (DMP-1)的表达。细胞碱性磷酸酶(ALP)染色分析诱导第7天的细胞ALP活性,茜素红染色评估诱导第21天矿化结节的形成。结果:45S5提取液培养基pH为8.65±0.01,与对照组差异无统计学意义(P < 0.05)。45S5诱导培养基的硅离子浓度为(1.56±0.07)mmol/L,高于对照组(0.08±0.01)mmol/L (PP>0.05)。Western blot结果显示,与对照组相比,45S5组LC3B-Ⅱ/Ⅰ比值升高,P62表达降低(pppp1)。结论:细胞自噬参与了1 mg/mL 45S5体外诱导APCs的成牙性分化。
{"title":"Bioactive glass 45S5 promotes odontogenic differentiation of apical papilla cells through autophagy.","authors":"Weilin Liu, Can Su, Caiyun Cui","doi":"10.7518/hxkq.2025.2024177","DOIUrl":"10.7518/hxkq.2025.2024177","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Objectives: &lt;/strong&gt;The mechanism of the odontogenic differentiation of apical papillary cells (APCs) stimulated by bioactive glass 45S5 is still unclear. This study aims to investigate the effect of autophagy on the odontogenic differentiation of APCs stimulated by bioactive glass 45S5.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;APCs were isolated and cultured &lt;i&gt;in vitro&lt;/i&gt;, and the cell origin was identified by flow cytometry. The culture medium was prepared with 1 mg/mL 45S5, and its pH and ion concentration were determined. The experiments were divided into control, 45S5, and 3-methyladenine (3-MA) 45S5 groups. In the 45S5 group, APCs were induced to culture with 1 mg/mL 45S5. In the 3-MA 45S5 group, the autophagy inhibitor 3-MA was added to 1 mg/mL 45S5. Protein immunoblotting assay (Western blot) was used to detect the expression of autophagy-associated proteins of microtubule-associated protein 1 light-chain 3β (LC3B) and P62 after 24 h of induction culture in each group. Real-time quantitative polymerase chain reaction (RT-qPCR) was used to detect the expression of bone sialoprotein (BSP), Runt-related transcription factor 2 (Runx2), dentin sialophosphoprotein (DSPP), and dentin matrix protein-1 (DMP-1) after 7 d of induction culture. Cellular alkaline phosphatase (ALP) staining analyzed cellular ALP activity at 7 d of induction, and alizarin red staining evaluated the formation of mineralized nodules at 21 d of induction.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;The pH of the 45S5 extract culture medium was 8.65±0.01, which was not significantly different from that of the control group (&lt;i&gt;P&lt;/i&gt;&gt;0.05). The silicon ion concentration of the 45S5 induction culture medium was (1.56±0.07) mmol/L, which was higher than that of the control group (0.08±0.01) mmol/L (&lt;i&gt;P&lt;/i&gt;&lt;0.05). The calcium ion concentration of the 45S5 induction culture was (1.57±0.15) mmol/L, which was not significantly different from that of the control group (&lt;i&gt;P&lt;/i&gt;&gt;0.05). Western blot results showed that LC3B-Ⅱ/Ⅰ ratio increased and P62 expression decreased in the 45S5 group compared with those in the control group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). By contrast, the ratio decreased and the expression increased in the 3-MA 45S5 group compared with those in the 45S5 group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). RT-qPCR results showed that the expression of BSP, Runx2, DMP-1, and DSPP enhanced in the 45S5 group compared with that in the control group (&lt;i&gt;P&lt;/i&gt;&lt;0.05), but the expression decreased in the 3-MA 45S5 group compared with that in the 45S5 group (&lt;i&gt;P&lt;/i&gt;&lt;0.05). Semi-quantitative analysis of ALP staining and alizarin red staining showed that the ALP activity was enhanced, and the formation mineralized nodule increased in the 45S5 group compared with those in the control group. The ALP activity weakened, and the formation mineralized nodules were reduced in the 3-MA 45S5 group compared with that those in the 45S5 group.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusions: &lt;/strong&gt;Cell autophagy participates in the odontogenic differen","PeriodicalId":94028,"journal":{"name":"Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology","volume":"43 1","pages":"37-45"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917504/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Biomechanical analysis of three kinds of rigid internal fixation methods for condylar head fractures. 髁突头骨折三种刚性内固定方法的生物力学分析。
Junhui Sun, Duoduo Lan, Dong Wang, Yao Xu, Zeyu Wang, Chenchen Zhang, Kai Zhang, Tao Xu

Objectives: This study aims to analyze the biomechanics of three kinds of rigid internal fixation methods for condylar head fractures.

Methods: A three dimensional finite element model of the normal mandible was constructed. It was then used to prepare condylar head fracture finite element model and three kinds of rigid internal fixation finite element model (unilateral tension screw, bilateral tension screw, tension screw+titanium plate). The mechanical characteristics and changes of the mandible condyle under the same mechanical conditions were compared among the three different rigid internal fixation methods.

Results: The maximum equivalent stress and displacement of the non-free end of condyle under the rigid internal fixation method of unilateral tension screw were 71.03 MPa and 4.72 mm, respectively. The maximum equivalent stress and displacement of the free end of condyle were 78.45 MPa and 4.50 mm, respectively. The maximum stress of fracture suture was 3.27 MPa. The maximum equivalent stress and displacement of the non-free end of condyle under the rigid internal fixation method of bilateral tension screw were 70.52 MPa and 4.00 mm, respectively. The maximum equivalent stress and displacement of the free end of condyle were 72.49 MPa and 3.85 mm, respectively. The maximum stress of fracture suture was 2.33 MPa. The maximum equivalent stress and maximum displacement of the non-free end of condyle under the rigid internal fixation method of tension screw+titanium plate were 67.26 MPa and 2.66 mm, respectively. The maximum equivalent stress and maximum displacement of the free end of condyle were 69.66 MPa and 2.50 mm, respectively. The maximum stress of fracture suture was 2.18 MPa.

Conclusions: The tension screw+titanium plate rigid internal fixation method is the most conducive to biomechanical distribution for condylar head fractures.

目的:分析髁突头骨折的三种刚性内固定方法的生物力学性能。方法:建立正常下颌骨三维有限元模型。然后用它制备髁头骨折有限元模型和三种刚性内固定有限元模型(单侧张力螺钉、双侧张力螺钉、张力螺钉+钛板)。比较三种不同的刚性内固定方法在相同力学条件下下颌骨髁突的力学特性及变化。结果:单侧张力螺钉刚性内固定方法下髁突非自由端最大等效应力和位移分别为71.03 MPa和4.72 mm。髁突自由端最大等效应力为78.45 MPa,最大等效位移为4.50 mm。骨折缝合处最大应力为3.27 MPa。双侧张力螺钉刚性内固定方法下髁突非自由端最大等效应力和位移分别为70.52 MPa和4.00 mm。髁突自由端最大等效应力为72.49 MPa,最大等效位移为3.85 mm。骨折缝合处最大应力为2.33 MPa。拉力螺钉+钛板刚性内固定方式下髁突非自由端最大等效应力和最大位移分别为67.26 MPa和2.66 mm。髁突自由端最大等效应力为69.66 MPa,最大位移为2.50 mm。骨折缝合处最大应力为2.18 MPa。结论:张力螺钉+钛板刚性内固定方法最有利于髁头骨折的生物力学分布。
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引用次数: 0
A cross-sectional study on improving clinical efficiency through centralized digital impression. 集中数字印模提高临床效率的横断面研究。
Yingxin Xu

Objectives: This study aims to explore the effect of improving clinical efficiency by replacing traditional impression workflow with centralized digital impression workflow.

Methods: The department of prosthodontics in Center of Stomatology, Peking University Shenzhen Hospital has improved the clinical workflow by replacing the traditional impression made by doctors using impression materials for each patient with a centralized digital impression made by one technician for all patients in the department. This cross-sectional study recorded the chairside time required for impression taking in patients undergoing single posterior zirconia full crown restoration before clinical process improvement; the time required for centralized digital impression production; the comfort level of patients; and the adjacency relationship, occlusal contact relationship, and time required for prostheses adjusting (i.e., whether centralized digital impressions would compromise the quality of pro-stheses and increase the time of prostheses adjusting).

Results: The average time to make a traditional impression was (9.98±1.41) min, and the average time required for each patient to make a centralized digital impression was (5.98±1.49) min, which was shorter than that to used make a traditional impression (P<0.05). Centralized digital impression made patients feel more comfortable compared with traditional impression (P<0.05). The adjacency relationship of restorations by centralized digital impression was more appropriate (P<0.05), and no significant difference in occlusal relationship was found (P>0.05). The time required for adjusting prostheses also had no significant differences (P>0.05).

Conclusions: Centralized digital impression can improve clinical efficiency for patients undergoing single posterior zirconia crown restoration. The time for impression taking is shorter, and patients feel more comfortable without compromising the quality of the prostheses.

目的:探讨集中式数字化印象工作流程取代传统印象工作流程对提高临床效率的影响。方法:北京大学深圳医院口腔中心修复科将传统的由医生对每位患者使用印模材料进行印模的做法,改为由一名技术人员对全科患者进行集中的数字印模,改进了临床工作流程。本横断面研究记录了在临床过程改善前,接受单后牙氧化锆全冠修复的患者在椅侧进行印模所需的时间;集中数字印模制作所需的时间;患者的舒适程度;以及修复体调整所需的邻接关系、咬合接触关系和时间(即集中数字印模是否会影响修复体的质量,增加修复体调整的时间)。结果:传统印模的平均时间为(9.98±1.41)min,每位患者进行集中数字印模的平均时间为(5.98±1.49)min,比使用传统印模的时间短(PPPP>0.05)。两组调整义肢所需时间差异无统计学意义(P < 0.05)。结论:集中式数字印模可提高单后牙氧化锆冠修复患者的临床疗效。印模时间更短,患者感觉更舒适,而不影响假体的质量。
{"title":"A cross-sectional study on improving clinical efficiency through centralized digital impression.","authors":"Yingxin Xu","doi":"10.7518/hxkq.2024.2024159","DOIUrl":"10.7518/hxkq.2024.2024159","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to explore the effect of improving clinical efficiency by replacing traditional impression workflow with centralized digital impression workflow.</p><p><strong>Methods: </strong>The department of prosthodontics in Center of Stomatology, Peking University Shenzhen Hospital has improved the clinical workflow by replacing the traditional impression made by doctors using impression materials for each patient with a centralized digital impression made by one technician for all patients in the department. This cross-sectional study recorded the chairside time required for impression taking in patients undergoing single posterior zirconia full crown restoration before clinical process improvement; the time required for centralized digital impression production; the comfort level of patients; and the adjacency relationship, occlusal contact relationship, and time required for prostheses adjusting (i.e., whether centralized digital impressions would compromise the quality of pro-stheses and increase the time of prostheses adjusting).</p><p><strong>Results: </strong>The average time to make a traditional impression was (9.98±1.41) min, and the average time required for each patient to make a centralized digital impression was (5.98±1.49) min, which was shorter than that to used make a traditional impression (<i>P</i><0.05). Centralized digital impression made patients feel more comfortable compared with traditional impression (<i>P</i><0.05). The adjacency relationship of restorations by centralized digital impression was more appropriate (<i>P</i><0.05), and no significant difference in occlusal relationship was found (<i>P</i>>0.05). The time required for adjusting prostheses also had no significant differences (<i>P</i>>0.05).</p><p><strong>Conclusions: </strong>Centralized digital impression can improve clinical efficiency for patients undergoing single posterior zirconia crown restoration. The time for impression taking is shorter, and patients feel more comfortable without compromising the quality of the prostheses.</p>","PeriodicalId":94028,"journal":{"name":"Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology","volume":"43 1","pages":"63-67"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917509/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018878","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
L-shape technique with concentrated growth factor for horizontal bone defects in the maxillary anterior region: a clinical and radiographic study. l形技术加浓缩生长因子治疗上颌前区水平骨缺损的临床与影像学研究。
Ruiwen Shi, Hu Yang, Yue Liu, Yilin Shi, Shengben Zhang, Yu Liu, Feng Song, Jing Lan

Objectives: To study the clinical effect of the L-shape technique combined with concentrated growth factor on the horizontal bone defects of maxillary anterior teeth.

Methods: Twenty-five implants from 25 patients who underwent single maxillary anterior tooth implantation with simultaneous bone grafting were selected as the study subjects. Based on the bone grafting techniques, the patients were divided into a test group (L-shaped technique with guided bone regeneration combined with concentrated growth factor, 11 cases) and a control group (traditional guided bone regeneration combined with concentrated growth factor, 14 cases). The early discomfort and wound healing conditions in the two groups at two weeks after surgery were compared. The horizontal bone thickness, vertical bone thickness, and grayscale values in the augmentation area were measured immediately postsurgery and six months after surgery. Implant stability, hard tissue resorption within six months, and grayscale values were compared between the two groups.

Results: Differences in early discomfort, wound healing, implant stability, and grayscale values between the two groups were not statistically significant (P>0.05). Vertical bone thickness in the test group was significantly better than that in the control group at six months after surgery (P<0.05). The variation in horizontal bone thickness in the test group was significantly higher than that in the control group (P<0.05).

Conclusions: The application of the L-shape technique with concentrated growth factor for horizontal bone defects in the anterior maxillary area yielded satisfactory short-term results in terms of bone augmentation, early discomfort, wound healing, and implant stability at six months after surgery.

目的:探讨l形技术联合浓缩生长因子治疗上颌前牙水平骨缺损的临床效果。方法:选取25例单行上颌前牙种植同时植骨的患者25颗种植体作为研究对象。根据植骨技术的不同,将患者分为试验组(l型引导骨再生联合浓缩生长因子,11例)和对照组(传统引导骨再生联合浓缩生长因子,14例)。比较两组患者术后2周的早期不适及创面愈合情况。分别于术后即刻及术后6个月测量增强区水平骨厚度、垂直骨厚度及灰度值。比较两组种植体稳定性、6个月内硬组织吸收及灰度值。结果:两组患者早期不适、创面愈合、种植体稳定性、灰度值差异无统计学意义(P < 0.05)。实验组术后6个月垂直骨厚度明显优于对照组(ppp)结论:上颌前区水平骨缺损采用浓缩生长因子l型技术,术后6个月骨增强、早期不适、创面愈合、种植体稳定性短期效果满意。
{"title":"L-shape technique with concentrated growth factor for horizontal bone defects in the maxillary anterior region: a clinical and radiographic study.","authors":"Ruiwen Shi, Hu Yang, Yue Liu, Yilin Shi, Shengben Zhang, Yu Liu, Feng Song, Jing Lan","doi":"10.7518/hxkq.2024.2024268","DOIUrl":"10.7518/hxkq.2024.2024268","url":null,"abstract":"<p><strong>Objectives: </strong>To study the clinical effect of the L-shape technique combined with concentrated growth factor on the horizontal bone defects of maxillary anterior teeth.</p><p><strong>Methods: </strong>Twenty-five implants from 25 patients who underwent single maxillary anterior tooth implantation with simultaneous bone grafting were selected as the study subjects. Based on the bone grafting techniques, the patients were divided into a test group (L-shaped technique with guided bone regeneration combined with concentrated growth factor, 11 cases) and a control group (traditional guided bone regeneration combined with concentrated growth factor, 14 cases). The early discomfort and wound healing conditions in the two groups at two weeks after surgery were compared. The horizontal bone thickness, vertical bone thickness, and grayscale values in the augmentation area were measured immediately postsurgery and six months after surgery. Implant stability, hard tissue resorption within six months, and grayscale values were compared between the two groups.</p><p><strong>Results: </strong>Differences in early discomfort, wound healing, implant stability, and grayscale values between the two groups were not statistically significant (<i>P></i>0.05). Vertical bone thickness in the test group was significantly better than that in the control group at six months after surgery (<i>P</i><0.05). The variation in horizontal bone thickness in the test group was significantly higher than that in the control group (<i>P</i><0.05).</p><p><strong>Conclusions: </strong>The application of the L-shape technique with concentrated growth factor for horizontal bone defects in the anterior maxillary area yielded satisfactory short-term results in terms of bone augmentation, early discomfort, wound healing, and implant stability at six months after surgery.</p>","PeriodicalId":94028,"journal":{"name":"Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology","volume":"43 1","pages":"76-83"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917517/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143017570","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Practice and challenge of age-friendly functional restoration of stomatognathic system based on the strategy of functional tooth loss. 基于功能牙缺失策略的年龄友好型口颌系统功能修复的实践与挑战。
Yiting Cheng, Yi Man, Yang Liu, He Cai, Ran Cheng, Li Cheng, Fanglong Wu, Hongkun Wu, Fanyuan Yu, Xueyang Liao, Yimin Sun, Jing Wang, Xue Yang, Jinyi Zhu, Xingqun Cheng, Zumu Yi, Ling Ye, Tao Hu

Geriatric oral health care encounters significant challenges with the increase in the proportion of older individuals. Age-related changes in the dentition, muscles, and joints result in a decline in objective masticatory function, subjective restoration requirements, and acceptability among the elderly population, with individual variations influenced by systemic health. Considering functional requirements, the adaptability of stomatognathic and systemic health conditions, health economics and other factors, the authors believe that it should not be limited to the conventional "one-to-one" strategy for replacing missing teeth in geriatric prosthodontics. There is an urgent need for a precise and adaptable restoration strategy that is more suitable for older individuals. The proposal of a new concept of functional tooth loss updates the minimal restoration standards for elderly patients and establishes the theory of age-friendly functional restoration. Based on the restoration strategy of functional tooth loss, this paper proposes a new concept termed "age-friendly functional restoration of the stomatognathic system", which integrates treatment considerations including endodontics, periodontology, mucosa, muscles, temporomandibular joint, and systemic health. Efforts should be made in four areas as follows. Firstly, the "assessment of accessible function" should be enhanced by considering the interrelationship between stomatognathic and systemic health. Secondly, the "evaluation of appropriate function" is supposed to be optimised in view of subjective needs and objective evaluation of the stomatognathic system. Moreover, the "formulation of treatment plans" needs to be accomplished with the aid of assistive technologies, such as artificial intelligence, to accurately exert appropriate functional restoration. Lastly, the "management and maintenance of health" is likely to be strengthened through follow-ups, propaganda and education, and preventive healthcare, so as to improve quality of life and ultimately achieve healthy ageing among older individuals.

随着老年人比例的增加,老年口腔保健面临重大挑战。与年龄相关的牙列、肌肉和关节变化导致老年人客观咀嚼功能、主观修复需求和可接受性的下降,个体差异受全身健康的影响。综合考虑功能需求、口颌及全身健康状况的适应性、卫生经济学等因素,笔者认为老年口腔修复不应局限于传统的“一对一”补牙策略。迫切需要一种更适合老年人的精确和适应性强的恢复策略。功能性牙缺失新概念的提出更新了老年患者的最小修复标准,建立了老年人友好型功能修复理论。基于功能性牙缺失的修复策略,本文提出了“年龄友好型口牙系统功能修复”的新概念,该概念综合了牙髓学、牙周学、黏膜、肌肉、颞下颌关节和全身健康等治疗考虑。应在以下四个方面作出努力。首先,考虑到口腔与全身健康的相互关系,加强“可达功能评估”。其次,结合口颌系统的主观需求和客观评价,优化“适当功能评价”。此外,“治疗方案的制定”需要借助人工智能等辅助技术来完成,以准确发挥适当的功能恢复。最后,可以通过后续行动、宣传教育和预防性保健来加强“健康管理和维护”,从而提高生活质量,最终实现老年人健康老龄化。
{"title":"Practice and challenge of age-friendly functional restoration of stomatognathic system based on the strategy of functional tooth loss.","authors":"Yiting Cheng, Yi Man, Yang Liu, He Cai, Ran Cheng, Li Cheng, Fanglong Wu, Hongkun Wu, Fanyuan Yu, Xueyang Liao, Yimin Sun, Jing Wang, Xue Yang, Jinyi Zhu, Xingqun Cheng, Zumu Yi, Ling Ye, Tao Hu","doi":"10.7518/hxkq.2025.2024188","DOIUrl":"10.7518/hxkq.2025.2024188","url":null,"abstract":"<p><p>Geriatric oral health care encounters significant challenges with the increase in the proportion of older individuals. Age-related changes in the dentition, muscles, and joints result in a decline in objective masticatory function, subjective restoration requirements, and acceptability among the elderly population, with individual variations influenced by systemic health. Considering functional requirements, the adaptability of stomatognathic and systemic health conditions, health economics and other factors, the authors believe that it should not be limited to the conventional \"one-to-one\" strategy for replacing missing teeth in geriatric prosthodontics. There is an urgent need for a precise and adaptable restoration strategy that is more suitable for older individuals. The proposal of a new concept of functional tooth loss updates the minimal restoration standards for elderly patients and establishes the theory of age-friendly functional restoration. Based on the restoration strategy of functional tooth loss, this paper proposes a new concept termed \"age-friendly functional restoration of the stomatognathic system\", which integrates treatment considerations including endodontics, periodontology, mucosa, muscles, temporomandibular joint, and systemic health. Efforts should be made in four areas as follows. Firstly, the \"assessment of accessible function\" should be enhanced by considering the interrelationship between stomatognathic and systemic health. Secondly, the \"evaluation of appropriate function\" is supposed to be optimised in view of subjective needs and objective evaluation of the stomatognathic system. Moreover, the \"formulation of treatment plans\" needs to be accomplished with the aid of assistive technologies, such as artificial intelligence, to accurately exert appropriate functional restoration. Lastly, the \"management and maintenance of health\" is likely to be strengthened through follow-ups, propaganda and education, and preventive healthcare, so as to improve quality of life and ultimately achieve healthy ageing among older individuals.</p>","PeriodicalId":94028,"journal":{"name":"Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology","volume":"43 1","pages":"15-27"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917511/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Guided bone regeneration therapy based on plaque control of peri-implantitis with follow-up at 7 years. 基于菌斑控制的引导骨再生治疗种植体周围炎随访7年。
Wenqi Su, Dandan Zhang, Yan Cheng, Wenjie Cui, Lang Lei, Houxuan Li

Peri-implantitis is a pathologic condition associated with dental plaque that occurs in the implant tissue and is characterized by inflammation of the mucous membrane surrounding the implant, followed by the progressive loss of supporting bone. In this study, a case of guided bone regeneration therapy based on plaque control of peri-implant inflammation was reported. Four years after surgery for the left second premolar implant, the patient presented with "left lower posterior tooth swelling and discomfort for more than 2 years". The X-ray periapical film showed a decrease in distal bone mineral density of implant, and the clinical diagnosis was peri-implantitis of the left second premolar. Implants underwent guided bone regeneration and regular periodontal maintenance treatment. Re-examination at 3.5 months, 11 months, 18 months, and 7 years showed that the alveolar bone height and bone mineral density were stable, and the periodontal depth became shallow. However, the gingival recession was mild. In the present case, follow-up at 7 years demonstrated that the clinical periodontal indexes could be remarkably improved after complete periodontal treatment for peri-implantitis, and the alveolar bone could be well restored and regenerated.

种植体周围炎是一种与牙菌斑相关的病理状况,发生在种植体组织中,其特征是种植体周围粘膜的炎症,随后是支撑骨的逐渐丧失。本研究报告了一例基于菌斑控制种植体周围炎症的引导骨再生治疗。左侧第二前磨牙种植术后4年,患者出现“左侧下后牙肿胀不适2年以上”。x线根尖周片显示种植体远端骨密度降低,临床诊断为左侧第二前磨牙种植体周围炎。种植体接受引导骨再生和常规牙周维持治疗。3.5个月、11个月、18个月、7年复查,牙槽骨高度、骨密度稳定,牙周深度变浅。然而,牙龈的衰退是温和的。本病例7年随访显示,牙周治疗完成后临床牙周指标明显改善,牙槽骨修复再生良好。
{"title":"Guided bone regeneration therapy based on plaque control of peri-implantitis with follow-up at 7 years.","authors":"Wenqi Su, Dandan Zhang, Yan Cheng, Wenjie Cui, Lang Lei, Houxuan Li","doi":"10.7518/hxkq.2024.2024131","DOIUrl":"10.7518/hxkq.2024.2024131","url":null,"abstract":"<p><p>Peri-implantitis is a pathologic condition associated with dental plaque that occurs in the implant tissue and is characterized by inflammation of the mucous membrane surrounding the implant, followed by the progressive loss of supporting bone. In this study, a case of guided bone regeneration therapy based on plaque control of peri-implant inflammation was reported. Four years after surgery for the left second premolar implant, the patient presented with \"left lower posterior tooth swelling and discomfort for more than 2 years\". The X-ray periapical film showed a decrease in distal bone mineral density of implant, and the clinical diagnosis was peri-implantitis of the left second premolar. Implants underwent guided bone regeneration and regular periodontal maintenance treatment. Re-examination at 3.5 months, 11 months, 18 months, and 7 years showed that the alveolar bone height and bone mineral density were stable, and the periodontal depth became shallow. However, the gingival recession was mild. In the present case, follow-up at 7 years demonstrated that the clinical periodontal indexes could be remarkably improved after complete periodontal treatment for peri-implantitis, and the alveolar bone could be well restored and regenerated.</p>","PeriodicalId":94028,"journal":{"name":"Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology","volume":"43 1","pages":"133-139"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917512/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Expert consensus on classification and diagnosis of congenital orofacial cleft. 先天性口面裂的分类和诊断的专家共识。
Chenghao Li, Yang An, Xiaohong Duan, Yingkun Guo, Shanling Liu, Hong Luo, Duan Ma, Yunyun Ren, Xudong Wang, Xiaoshan Wu, Hongning Xie, Hongping Zhu, Jun Zhu, Bing Shi

Congenital orofacial cleft, the most common birth defect in the maxillofacial region, exhibits a wide range of prognosis depending on the severity of deformity and underlying etiology. Non-syndromic congenital orofacial clefts typically present with milder deformities and more favorable treatment outcomes, whereas syndromic congenital orofacial clefts often manifest with concomitant organ abnormalities, which pose greater challenges for treatment and result in poorer prognosis. This consensus provides an elaborate classification system for varying degrees of orofacial clefts along with corresponding diagnostic and therapeutic guidelines. Results serve as a crucial resource for families to navigate prenatal screening results or make informed decisions regarding treatment options while also contributing significantly to preventing serious birth defects within the development of population.

先天性口面裂是颌面部最常见的先天性缺陷,其预后取决于畸形的严重程度和潜在的病因。非综合征型先天性口面裂畸形较轻,治疗效果较好,而综合征型先天性口面裂常伴有器官异常,治疗难度较大,预后较差。这一共识为不同程度的唇腭裂提供了一个详细的分类系统以及相应的诊断和治疗指南。结果是家庭了解产前筛查结果或就治疗方案作出知情决定的重要资源,同时也对预防人口发展中的严重出生缺陷作出重大贡献。
{"title":"Expert consensus on classification and diagnosis of congenital orofacial cleft.","authors":"Chenghao Li, Yang An, Xiaohong Duan, Yingkun Guo, Shanling Liu, Hong Luo, Duan Ma, Yunyun Ren, Xudong Wang, Xiaoshan Wu, Hongning Xie, Hongping Zhu, Jun Zhu, Bing Shi","doi":"10.7518/hxkq.2025.2024306","DOIUrl":"10.7518/hxkq.2025.2024306","url":null,"abstract":"<p><p>Congenital orofacial cleft, the most common birth defect in the maxillofacial region, exhibits a wide range of prognosis depending on the severity of deformity and underlying etiology. Non-syndromic congenital orofacial clefts typically present with milder deformities and more favorable treatment outcomes, whereas syndromic congenital orofacial clefts often manifest with concomitant organ abnormalities, which pose greater challenges for treatment and result in poorer prognosis. This consensus provides an elaborate classification system for varying degrees of orofacial clefts along with corresponding diagnostic and therapeutic guidelines. Results serve as a crucial resource for families to navigate prenatal screening results or make informed decisions regarding treatment options while also contributing significantly to preventing serious birth defects within the development of population.</p>","PeriodicalId":94028,"journal":{"name":"Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology","volume":"43 1","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917503/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical study on low-energy semiconductor laser treatment in the promotion of wound healing after maxillofacial fracture surgery. 低能量半导体激光治疗促进颌面部骨折术后创面愈合的临床研究。
Maojing Xiong, Lu Yang, Liyuan Ma, Lei Liu, Bo Yang

Objectives: This study aims to evaluate the clinical effect of low-energy semiconductor laser treatment on the promotion of wound healing after maxillofacial fracture surgery.

Methods: A prospective randomized controlled study was conducted. Patients with maxillofacial fractures who were hospitalized in the Department of Trauma and Plastic Surgery, West China Hospital of Stomatology, Sichuan University, from August 2021 to June 2023 were selected as the study subjects and randomly divided into experimental and control groups. The experimental group was treated with a low-energy semiconductor laser once a day for six consecutive days after daily routine dressing change on the first day after surgery. The control group only underwent routine dressing change treatment and did not receive low-energy semiconductor laser treatment. Wound healing times, wound healing conditions, modified Stony Brook scar evaluation scale (mSBSES) scores, pain indices, and wound infection rates were compared between the two groups.

Results: A total of 211 patients were included in this study. A total of 104 and 107 cases comprised the experimental and control groups, respectively. A total of 128 males and 83 females were included. After low-energy semiconductor laser treatment, the facial skin wound healing time of the experimental group was found to be significantly shorter than that of the control group (P<0.05). Moreover, the wound grade A healing rate of the experimental group was higher than that of the control group on the seventh day after surgery (P<0.05). Among postoperative facial skin wound evaluation indices, the mSBSES scores of the experimental group at all observation points were higher than those of the control group (P<0.05), and the scores of the experimental group were higher than those of the control group in terms of wound width reduction, height reduction, color lightening, and incision line loss (P<0.05). In postoperative wound pain evaluation, the pain index of the experimental group after low-energy semiconductor laser treatment was significantly lower than that of the control group (P<0.05). No significant difference in wound infection rates was found between the two groups (P>0.05).

Conclusions: For facial skin wounds in maxillofacial fracture surgery, low-energy semiconductor laser treatment can effectively promote wound healing, improve wound healing quality, fade scars, and relieve wound pain.

目的:探讨低能量半导体激光治疗促进颌面部骨折术后创面愈合的临床效果。方法:采用前瞻性随机对照研究。选择2021年8月至2023年6月在四川大学华西口腔医院创伤与整形外科住院的颌面部骨折患者作为研究对象,随机分为实验组和对照组。实验组患者术后第1天常规换药后,采用低能量半导体激光治疗,每天1次,连续6天。对照组只进行常规换药治疗,不进行低能量半导体激光治疗。比较两组患者创面愈合时间、创面愈合情况、改良石溪疤痕评价量表(mSBSES)评分、疼痛指数、创面感染率。结果:本研究共纳入211例患者。试验组104例,对照组107例。共包括128名男性和83名女性。低能量半导体激光治疗后,实验组面部皮肤创面愈合时间明显短于对照组(PPPPPP>0.05)。结论:对于颌面部骨折手术面部皮肤创面,低能量半导体激光治疗可有效促进创面愈合,提高创面愈合质量,淡化疤痕,减轻创面疼痛。
{"title":"Clinical study on low-energy semiconductor laser treatment in the promotion of wound healing after maxillofacial fracture surgery.","authors":"Maojing Xiong, Lu Yang, Liyuan Ma, Lei Liu, Bo Yang","doi":"10.7518/hxkq.2025.2024237","DOIUrl":"10.7518/hxkq.2025.2024237","url":null,"abstract":"<p><strong>Objectives: </strong>This study aims to evaluate the clinical effect of low-energy semiconductor laser treatment on the promotion of wound healing after maxillofacial fracture surgery.</p><p><strong>Methods: </strong>A prospective randomized controlled study was conducted. Patients with maxillofacial fractures who were hospitalized in the Department of Trauma and Plastic Surgery, West China Hospital of Stomatology, Sichuan University, from August 2021 to June 2023 were selected as the study subjects and randomly divided into experimental and control groups. The experimental group was treated with a low-energy semiconductor laser once a day for six consecutive days after daily routine dressing change on the first day after surgery. The control group only underwent routine dressing change treatment and did not receive low-energy semiconductor laser treatment. Wound healing times, wound healing conditions, modified Stony Brook scar evaluation scale (mSBSES) scores, pain indices, and wound infection rates were compared between the two groups.</p><p><strong>Results: </strong>A total of 211 patients were included in this study. A total of 104 and 107 cases comprised the experimental and control groups, respectively. A total of 128 males and 83 females were included. After low-energy semiconductor laser treatment, the facial skin wound healing time of the experimental group was found to be significantly shorter than that of the control group (<i>P</i><0.05). Moreover, the wound grade A healing rate of the experimental group was higher than that of the control group on the seventh day after surgery (<i>P</i><0.05). Among postoperative facial skin wound evaluation indices, the mSBSES scores of the experimental group at all observation points were higher than those of the control group (<i>P</i><0.05), and the scores of the experimental group were higher than those of the control group in terms of wound width reduction, height reduction, color lightening, and incision line loss (<i>P</i><0.05). In postoperative wound pain evaluation, the pain index of the experimental group after low-energy semiconductor laser treatment was significantly lower than that of the control group (<i>P</i><0.05). No significant difference in wound infection rates was found between the two groups (<i>P</i>>0.05).</p><p><strong>Conclusions: </strong>For facial skin wounds in maxillofacial fracture surgery, low-energy semiconductor laser treatment can effectively promote wound healing, improve wound healing quality, fade scars, and relieve wound pain.</p>","PeriodicalId":94028,"journal":{"name":"Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology","volume":"43 1","pages":"68-75"},"PeriodicalIF":0.0,"publicationDate":"2025-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11917507/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143018920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Conservative treatment of pathological fracture after multiple odontogenic keratocyst surgery: a case report and literature analysis. 多发牙源性角化囊肿术后病理性骨折的保守治疗1例并文献分析。
Chen Xu, Hongguang Chang, Qiang Shao, Yonghai Song

Pathological fractures after jaw cyst surgery are rare clinically but are a serious complication. Once a pathological fracture occurs, treatment time and economic costs increase, and doctors face difficulty in handling it. This article reports a case of a patient with mandibular pathological fractures after multiple odontogenic keratocyst surgery of the jaw. Mandibular lesions were located in the bilateral mandibular angles and had macrocystic changes. We adopted a conservative treatment plan, and the treatment effect was good. We also discussed and analyzed relevant literature to provide a reference for clinicians.

颌骨囊肿术后病理性骨折在临床上很少见,但却是严重的并发症。一旦发生病理性骨折,治疗时间和经济成本增加,医生处理困难。本文报告一例多牙源性角化囊肿手术后出现下颌骨病理性骨折的病例。下颌病变位于双侧下颌角,有大囊性改变。我们采用保守治疗方案,治疗效果良好。并对相关文献进行讨论和分析,为临床医生提供参考。
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Hua xi kou qiang yi xue za zhi = Huaxi kouqiang yixue zazhi = West China journal of stomatology
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