Pub Date : 2025-08-25DOI: 10.1016/j.jcct.2025.08.005
Taha Ahmed, Daniel Thomas Mathew, Gabriel Najarro, Bryan J Wells, Puja K Mehta
{"title":"Coronary Computed Tomography Angiography (CCTA) utilization in acute Spontaneous Coronary Artery Dissection (SCAD) hospitalizations in the United States from 2017 to 2022.","authors":"Taha Ahmed, Daniel Thomas Mathew, Gabriel Najarro, Bryan J Wells, Puja K Mehta","doi":"10.1016/j.jcct.2025.08.005","DOIUrl":"10.1016/j.jcct.2025.08.005","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451788/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984021","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-21DOI: 10.1016/j.jcct.2025.08.004
Ashish Manohar, Ashley Wong, Edgard Castillo, Allison Gunderson, Gabriel Mistelbauer, Shadi Peighambari Bagherzadeh, Francois Haddad, Kadir Caliskan, Ricardo P J Budde, Alexander Hirsch, Seung-Pyo Lee, Whal Lee, Anjali Owens, Harold Litt, Matthew Wheeler, Deborah H Kwon, W H Wilson Tang, Koen Nieman
Background: Left ventricular noncompaction (LVNC), or hypertrabeculation, is a myocardial condition that remains challenging to diagnose and differentiate from other cardiomyopathies. This study evaluated the ability of cardiac CT to differentiate between LVNC, hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and controls using fractal analysis of LV trabeculae.
Methods: Subjects with LVNC, HCM, DCM, as well as controls, who underwent coronary CT angiography were included. LV trabecular structure was quantified using fractal analysis on a stack of 15 short-axis CT images. For each subject, maximum (FDmax) and average (FDglobal) fractal dimensions were reported. A subset of subjects also had clinically acquired cardiac MRI (CMR) exams for comparison. One-way ANOVA, Pearson correlation, and Bland-Altman analysis were used for statistical analysis.
Results: The study included 313 subjects (median age: 58.8 [48.1-68.0] years, 153 male) categorized into Control (89), LVNC (46), HCM (106), and DCM (72) cohorts. FDmax was significantly higher in LVNC (1.379 ± 0.047) than in Control (1.305 ± 0.033), HCM (1.321 ± 0.040), and DCM (1.344 ± 0.054) cohorts; all p < 0.001. Similarly, FDglobal was significantly higher in LVNC (1.279 ± 0.041) than in the other cohorts; all p < 0.05. In a subset of 132 subjects with both CT and CMR exams, fractal dimensions from the two modalities were strongly correlated (r = 0.63, p < 0.0001), with CT-derived values being higher (1.337 ± 0.049 vs. 1.262 ± 0.045, p < 0.0001).
Conclusions: CT-derived fractal dimensions of LV trabecular structure were significantly higher in LVNC compared to control subjects, HCM, and DCM. CT-derived fractal dimensions strongly correlated with, but were higher than, those from cardiac MRI in the same subjects.
{"title":"Cardiac CT fractal analysis of LV noncompaction and common cardiomyopathies.","authors":"Ashish Manohar, Ashley Wong, Edgard Castillo, Allison Gunderson, Gabriel Mistelbauer, Shadi Peighambari Bagherzadeh, Francois Haddad, Kadir Caliskan, Ricardo P J Budde, Alexander Hirsch, Seung-Pyo Lee, Whal Lee, Anjali Owens, Harold Litt, Matthew Wheeler, Deborah H Kwon, W H Wilson Tang, Koen Nieman","doi":"10.1016/j.jcct.2025.08.004","DOIUrl":"10.1016/j.jcct.2025.08.004","url":null,"abstract":"<p><strong>Background: </strong>Left ventricular noncompaction (LVNC), or hypertrabeculation, is a myocardial condition that remains challenging to diagnose and differentiate from other cardiomyopathies. This study evaluated the ability of cardiac CT to differentiate between LVNC, hypertrophic cardiomyopathy (HCM), dilated cardiomyopathy (DCM), and controls using fractal analysis of LV trabeculae.</p><p><strong>Methods: </strong>Subjects with LVNC, HCM, DCM, as well as controls, who underwent coronary CT angiography were included. LV trabecular structure was quantified using fractal analysis on a stack of 15 short-axis CT images. For each subject, maximum (FD<sub>max</sub>) and average (FD<sub>global</sub>) fractal dimensions were reported. A subset of subjects also had clinically acquired cardiac MRI (CMR) exams for comparison. One-way ANOVA, Pearson correlation, and Bland-Altman analysis were used for statistical analysis.</p><p><strong>Results: </strong>The study included 313 subjects (median age: 58.8 [48.1-68.0] years, 153 male) categorized into Control (89), LVNC (46), HCM (106), and DCM (72) cohorts. FD<sub>max</sub> was significantly higher in LVNC (1.379 ± 0.047) than in Control (1.305 ± 0.033), HCM (1.321 ± 0.040), and DCM (1.344 ± 0.054) cohorts; all p < 0.001. Similarly, FD<sub>global</sub> was significantly higher in LVNC (1.279 ± 0.041) than in the other cohorts; all p < 0.05. In a subset of 132 subjects with both CT and CMR exams, fractal dimensions from the two modalities were strongly correlated (r = 0.63, p < 0.0001), with CT-derived values being higher (1.337 ± 0.049 vs. 1.262 ± 0.045, p < 0.0001).</p><p><strong>Conclusions: </strong>CT-derived fractal dimensions of LV trabecular structure were significantly higher in LVNC compared to control subjects, HCM, and DCM. CT-derived fractal dimensions strongly correlated with, but were higher than, those from cardiac MRI in the same subjects.</p>","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12520610/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984108","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-05-31DOI: 10.1016/j.jcct.2025.05.238
Ahmed Aldajani, Yoshito Kadoya, Gary Small, Benjamin J W Chow
{"title":"Triple-vessel coronary cameral fistula as a cause of diffuse coronary artery ectasia: Diagnostic insights from coronary CT angiography.","authors":"Ahmed Aldajani, Yoshito Kadoya, Gary Small, Benjamin J W Chow","doi":"10.1016/j.jcct.2025.05.238","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.05.238","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144251607","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.jcct.2024.05.169
M. Erbay, S. Susarla, D. Lee, V. Manubolu, A. Kinninger, H. Sandhu, D. Behjatnia, O. Bikhazi, K. Ngo, A. Jung, I. Yusufu, T. Ahmad, Budoff M
{"title":"Distribution Of Coronary Plaque Subtypes Among Races Quantified By Automated Coronary Plaque Analysis","authors":"M. Erbay, S. Susarla, D. Lee, V. Manubolu, A. Kinninger, H. Sandhu, D. Behjatnia, O. Bikhazi, K. Ngo, A. Jung, I. Yusufu, T. Ahmad, Budoff M","doi":"10.1016/j.jcct.2024.05.169","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.169","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":"130 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141709023","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.jcct.2024.05.150
S. Krishnan, D. Li, S. Mao, F. Flores, Y. Gao, S. Luo, M. Budoff
{"title":"Comprehensive Assessment Of CT Hounsfield Unit Variation Within Patients, Scanners, And Integrated Measures","authors":"S. Krishnan, D. Li, S. Mao, F. Flores, Y. Gao, S. Luo, M. Budoff","doi":"10.1016/j.jcct.2024.05.150","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.150","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":"136 40","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141713783","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.jcct.2024.05.189
D. Chamie, R. Okubo, Y. Sobue, U. Kaneko, H. Sato, S. Fujimoto, Y. Nozaki, T. Kajiya, T. Miyoshi, K. Ichikawa, M. Abe, T. Kitagawa, H. Ikenaga, K. Osawa, M. Saji, N. Iguchi, G. Nakazawa, K. Takahashi, T. Ijich, H. Mikamo, A. Kurata, M. Moroi, R. Iijima, A. Lansky, A. Demuyakor, H. Matsuo, U. Hoffmann, J. Min, J. Earls, R. Nakanishi
{"title":"Optimal Threshold For Characterizing Calcified Plaque On Ccta As Determined By Correlation With Oct","authors":"D. Chamie, R. Okubo, Y. Sobue, U. Kaneko, H. Sato, S. Fujimoto, Y. Nozaki, T. Kajiya, T. Miyoshi, K. Ichikawa, M. Abe, T. Kitagawa, H. Ikenaga, K. Osawa, M. Saji, N. Iguchi, G. Nakazawa, K. Takahashi, T. Ijich, H. Mikamo, A. Kurata, M. Moroi, R. Iijima, A. Lansky, A. Demuyakor, H. Matsuo, U. Hoffmann, J. Min, J. Earls, R. Nakanishi","doi":"10.1016/j.jcct.2024.05.189","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.189","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":"22 36","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141699837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.jcct.2024.05.202
G. Tremamunno, A. Varga-Szemes, U. Schoepf, E. Zsarnóczay, G. Aquino, J. O'Doherty, M. Vecsey-Nagy, T. Emrich
{"title":"Fully Automated Functional Assessment Of Pre-procedural Cardiac Ct Predicts Outcome In Transcatheter Aortic Valve Replacement Candidates","authors":"G. Tremamunno, A. Varga-Szemes, U. Schoepf, E. Zsarnóczay, G. Aquino, J. O'Doherty, M. Vecsey-Nagy, T. Emrich","doi":"10.1016/j.jcct.2024.05.202","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.202","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":"41 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141708713","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.jcct.2024.05.139
K. Atlas, C. Zhang, A. Reeves, D. Li, T. Atlas, M. Budoff, M. Naghavi
{"title":"AI-enabled Bone Mineral Density Measurement In Coronary Artery Calcium Scans Associated With High Coronary Artery Calcium Independently Of Conventional Risk Factors: Multi-ethnic Study Of Atherosclerosis (mesa)","authors":"K. Atlas, C. Zhang, A. Reeves, D. Li, T. Atlas, M. Budoff, M. Naghavi","doi":"10.1016/j.jcct.2024.05.139","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.139","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":"11 12","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141703480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-07-01DOI: 10.1016/j.jcct.2024.05.137
A. Alatoum, S. Pryia
{"title":"Comparative Analysis Of Coronary Calcium Scoring Using True Non-contrast And Photon-counting Detector Ct Virtual Non-contrast Reconstructions","authors":"A. Alatoum, S. Pryia","doi":"10.1016/j.jcct.2024.05.137","DOIUrl":"https://doi.org/10.1016/j.jcct.2024.05.137","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":"4 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141696808","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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