{"title":"Response to \"Evaluating the CT-STEMI study: The controversy over CCT and CMR for post-STEMI prognosis\".","authors":"Marco Gatti, Guglielmo Gallone, Tommaso D'Angelo, Camilla Torlasco, Alessandro Andreis, Riccardo Faletti","doi":"10.1016/j.jcct.2025.09.009","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.09.009","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145201479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-27DOI: 10.1016/j.jcct.2025.09.005
Weikai Dong, Jiaming Fan, Wei Li
{"title":"Evaluating the Early-HFpEF study: The controversies and future directions in peripheral arterial calcification and central arterial stiffness in T2DM.","authors":"Weikai Dong, Jiaming Fan, Wei Li","doi":"10.1016/j.jcct.2025.09.005","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.09.005","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145188055","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-23DOI: 10.1016/j.jcct.2025.09.002
Lukas J Moser, Tristan T Demmert, Konstantin Klambauer, Victor Schweiger, Victor Mergen, Michael Würdinger, Davide Di Vece, Andrea Biondo, Alexander Gotschy, Barbara Stähli, Martin Reiner, Jelena-R Ghadri, Robert Manka, Matthias Eberhard, Christian Templin, Hatem Alkadhi
Background: The diagnosis of spontaneous coronary artery dissection (SCAD) is made with invasive coronary angiography (ICA). The literature on the diagnostic performance of coronary CT angiography (coronary CTA) is sparse. The purpose of this study was to evaluate the performance of coronary CTA for the diagnosis of acute SCAD.
Methods: This prospective single-center study included 52 patients with SCAD confirmed by ICA and 70 patients with chest pain but without SCAD (control group), who all underwent coronary CTA. Two independent readers evaluated coronary CTA for SCAD, including vessel abnormalities and myocardial hypodensity. Accuracy, sensitivity, and specificity with 95 % confidence intervals (CI) were calculated using ICA as the reference standard. Coronary CTA imaging features of SCAD were correlated with diagnostic confidence using multivariable regression analysis. Interreader agreement was determined by Cohen's Kappa.
Results: Patient-level sensitivity of coronary CTA to diagnose SCAD ranged from 52 % (CI:38 %-66 %)-58 % (CI:43 %-71 %), with a specificity of 97 % (CI:90 %-100 %) and accuracy of 78 % (CI:69 %-85 %) and 80 % (CI:72 %-87 %) for both readers (Kappa = 0.891). Sensitivity and accuracy were higher for proximal (sensitivity 67 % (CI:38 %-88 %) and 73 % (CI:45 %-92 %); accuracy 93 % (CI:87 %-97 %) and 94 % (CI:89 %-98 %)) than for distal SCAD (sensitivity 40 % (CI:26 %-56 %) and 49 % (CI:34 %-64 %); accuracy 76 % (CI:68 %-83 %) and 80 % (CI:71 %-86 %)), while specificity was high irrespective of location (97 %; CI:91 %-99 %, resp.100 %). Additional myocardial hypodensity increased readers' confidence (beta coefficient -0.38; p = 0.11 for reader 1, and beta coefficient of -0.90; p = 0.004 for reader 2) and sensitivity (71 % (CI:57 %-83 %) and 65 % (CI:51 %-78 %), respectively), while reducing specificity (both 91 %, CI:82 %-97 %).
Conclusion: Coronary CTA has a poor sensitivity for the diagnosis of SCAD, while specificity is high irrespective of SCAD location. Patients with coronary CTA positive for SCAD might be deferred from ICA after careful consideration and when conservative management is intended.
{"title":"Diagnostic performance of coronary CT angiography to diagnose acute spontaneous coronary artery dissection.","authors":"Lukas J Moser, Tristan T Demmert, Konstantin Klambauer, Victor Schweiger, Victor Mergen, Michael Würdinger, Davide Di Vece, Andrea Biondo, Alexander Gotschy, Barbara Stähli, Martin Reiner, Jelena-R Ghadri, Robert Manka, Matthias Eberhard, Christian Templin, Hatem Alkadhi","doi":"10.1016/j.jcct.2025.09.002","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.09.002","url":null,"abstract":"<p><strong>Background: </strong>The diagnosis of spontaneous coronary artery dissection (SCAD) is made with invasive coronary angiography (ICA). The literature on the diagnostic performance of coronary CT angiography (coronary CTA) is sparse. The purpose of this study was to evaluate the performance of coronary CTA for the diagnosis of acute SCAD.</p><p><strong>Methods: </strong>This prospective single-center study included 52 patients with SCAD confirmed by ICA and 70 patients with chest pain but without SCAD (control group), who all underwent coronary CTA. Two independent readers evaluated coronary CTA for SCAD, including vessel abnormalities and myocardial hypodensity. Accuracy, sensitivity, and specificity with 95 % confidence intervals (CI) were calculated using ICA as the reference standard. Coronary CTA imaging features of SCAD were correlated with diagnostic confidence using multivariable regression analysis. Interreader agreement was determined by Cohen's Kappa.</p><p><strong>Results: </strong>Patient-level sensitivity of coronary CTA to diagnose SCAD ranged from 52 % (CI:38 %-66 %)-58 % (CI:43 %-71 %), with a specificity of 97 % (CI:90 %-100 %) and accuracy of 78 % (CI:69 %-85 %) and 80 % (CI:72 %-87 %) for both readers (Kappa = 0.891). Sensitivity and accuracy were higher for proximal (sensitivity 67 % (CI:38 %-88 %) and 73 % (CI:45 %-92 %); accuracy 93 % (CI:87 %-97 %) and 94 % (CI:89 %-98 %)) than for distal SCAD (sensitivity 40 % (CI:26 %-56 %) and 49 % (CI:34 %-64 %); accuracy 76 % (CI:68 %-83 %) and 80 % (CI:71 %-86 %)), while specificity was high irrespective of location (97 %; CI:91 %-99 %, resp.100 %). Additional myocardial hypodensity increased readers' confidence (beta coefficient -0.38; p = 0.11 for reader 1, and beta coefficient of -0.90; p = 0.004 for reader 2) and sensitivity (71 % (CI:57 %-83 %) and 65 % (CI:51 %-78 %), respectively), while reducing specificity (both 91 %, CI:82 %-97 %).</p><p><strong>Conclusion: </strong>Coronary CTA has a poor sensitivity for the diagnosis of SCAD, while specificity is high irrespective of SCAD location. Patients with coronary CTA positive for SCAD might be deferred from ICA after careful consideration and when conservative management is intended.</p>","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139421","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-20DOI: 10.1016/j.jcct.2025.09.004
Muhammet Cihat Çelik, Mehmet Murat Şahin, Macit Kalçık
{"title":"Balancing innovation and evidence: Coronary computed tomography angiography in preoperative valve surgery.","authors":"Muhammet Cihat Çelik, Mehmet Murat Şahin, Macit Kalçık","doi":"10.1016/j.jcct.2025.09.004","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.09.004","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145115812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-12DOI: 10.1016/j.jcct.2025.08.011
Alan Rozanski, Robert J H Miller, Heidi Gransar, Donghee Han, Sean W Hayes, John D Friedman, Leslee J Shaw, Daniel S Berman
{"title":"Reassessing pretest probability: Coronary artery calcium alone predicts obstructive CAD.","authors":"Alan Rozanski, Robert J H Miller, Heidi Gransar, Donghee Han, Sean W Hayes, John D Friedman, Leslee J Shaw, Daniel S Berman","doi":"10.1016/j.jcct.2025.08.011","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.08.011","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-02DOI: 10.1016/j.jcct.2025.08.010
Macit Kalçık, Mucahit Yetım
{"title":"Strengthening the evidence on air pollution and coronary heart diseases: Exposure and confounding challenges.","authors":"Macit Kalçık, Mucahit Yetım","doi":"10.1016/j.jcct.2025.08.010","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.08.010","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994858","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-09-02DOI: 10.1016/j.jcct.2025.08.009
Kirtipal Bhatia, Felipe Contreras Yametti, Júlia Pedraza Garriga, Maria Qureshi, Annalisa Filtz, Daniel Lorenzatti, Justin Johannesen, Carlos A Gongora, Aldo L Schenone, Leandro Slipczuk
{"title":"Coronary CT angiography versus invasive angiography for preoperative coronary assessment prior to valve surgery.","authors":"Kirtipal Bhatia, Felipe Contreras Yametti, Júlia Pedraza Garriga, Maria Qureshi, Annalisa Filtz, Daniel Lorenzatti, Justin Johannesen, Carlos A Gongora, Aldo L Schenone, Leandro Slipczuk","doi":"10.1016/j.jcct.2025.08.009","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.08.009","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144994863","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2025-08-26DOI: 10.1016/j.jcct.2025.08.007
Weikai Dong
{"title":"Evaluating the CT-STEMI study: The controversy over CCT and CMR for post-STEMI prognosis.","authors":"Weikai Dong","doi":"10.1016/j.jcct.2025.08.007","DOIUrl":"https://doi.org/10.1016/j.jcct.2025.08.007","url":null,"abstract":"","PeriodicalId":94071,"journal":{"name":"Journal of cardiovascular computed tomography","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2025-08-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144984064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
扫码关注我们
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号