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[Autologous peripheral stem cell transplantation in systemic sclerosis: An important step forward, but we must temper our enthusiasm!] 自体外周干细胞移植治疗系统性硬化症:向前迈出了重要一步，但我们必须缓和我们的热情!］
La Revue de medecine interne
Pub Date : 2023-12-05 DOI: 10.1016/j.revmed.2023.11.010
L Mouthon

Three prospective randomized studies have demonstrated the efficacy of autologous hematopoietic stem cell (HSC) transplantation in systemic sclerosis (SSc) on survival. These results encourage us to offer this therapy to patients who have a rapidly progressive disease and who have early symptoms but no advanced visceral involvement. HSC autograft can thus be discussed in patients with diffuse cutaneous SSc with a duration of the disease since the first visceral manifestations (cutaneous, cardiac, digestive, pulmonary, or renal) excluding Raynaud's phenomenon of less than 5 years. However, the indications for HSC autograft in SSc validated at European level and in the national diagnostic and care protocol (PNDS) are broader and some of these indications are debatable, in particular in patients with worsening diffuse interstitial lung disease. These indications are discussed in a reasoned way, taking into account the level of evidence and the toxicity of the HSC autograft.

三项前瞻性随机研究证明了自体造血干细胞(HSC)移植对系统性硬化症(SSc)患者生存的影响。这些结果鼓励我们为那些疾病进展迅速和有早期症状但没有晚期内脏受累的患者提供这种治疗。因此，在弥漫性皮肤SSc患者中，如果疾病持续时间自首次内脏表现(皮肤、心脏、消化、肺部或肾脏)起，排除雷诺现象少于5年，则可以讨论自体HSC移植。然而，在欧洲水平和国家诊断和护理方案(PNDS)中验证的SSc中自体HSC移植的适应症更广泛，其中一些适应症存在争议，特别是在弥漫性间质性肺疾病恶化的患者中。考虑到证据水平和自体造血干细胞移植的毒性，以合理的方式讨论了这些适应症。
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引用次数: 0
La symptomatologie digestive chez les patients infectés au COVID-19 COVID-19感染患者的消化症状学
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.190
W. Sellami, L. Chtourou, N. Baccouche, N. Khlif, M. Bahloul, N. Tahri, M. Bouaziz
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引用次数: 1
Vascularite rétinienne et hémorragie intravitréenne après la vaccination contre la Covid-19 : à propos d’une observation Covid-19疫苗接种后视网膜血管炎和玻璃内出血:关于观察
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.189
Y. Bouattour, M. Snoussi, S. Mekki, F. Frikha, M. Sameh, Z. Bahloul
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引用次数: 1
Morphée à la suite d’une vaccination anti-COVID-19 morphee在接种了抗covid -19疫苗后
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.163
M. Teamotuaitau, E. Desvaux, N. Ratti, N. Aslanbekova, S. Palat, G. Gondran, H. Bezanahary, É. Liozon, K. Ly, A. Fauchais, S. Parreau
{"title":"Morphée à la suite d’une vaccination anti-COVID-19","authors":"M. Teamotuaitau, E. Desvaux, N. Ratti, N. Aslanbekova, S. Palat, G. Gondran, H. Bezanahary, É. Liozon, K. Ly, A. Fauchais, S. Parreau","doi":"10.1016/j.revmed.2023.04.163","DOIUrl":"https://doi.org/10.1016/j.revmed.2023.04.163","url":null,"abstract":"","PeriodicalId":94122,"journal":{"name":"La Revue de medecine interne","volume":"25 1","pages":"A215 - A215"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88353028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Une myopathie nécrosante auto-immune à anti-SRP induite par une infection Covid-19 Covid-19感染引起的自身免疫性抗srp坏死性肌病
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.255
W. Helali, M. Essouri, W. Ben Elhaj, I. Oueslati, A. Dorgham, K. Touati, N. Khammassi
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引用次数: 0
L’antibiothérapie à large spectre est associée à une atteinte hépatique chez les patients infectés au COVID-19 广谱抗生素治疗与COVID-19感染患者的肝脏损伤有关
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.191
W. Sellami, L. Chtourou, N. Baccouche, N. Khlif, M. Bahloul, N. Tahri, M. Bouaziz
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引用次数: 0
Hépatopathies gravidiques associées à l’infection COVID-19 与COVID-19感染相关的妊娠肝病
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.210
W. Sellami, L. Chtourou, N. Baccouche, N. Khlif, M. Bahloul, N. Tahri, M. Bouaziz
{"title":"Hépatopathies gravidiques associées à l’infection COVID-19","authors":"W. Sellami, L. Chtourou, N. Baccouche, N. Khlif, M. Bahloul, N. Tahri, M. Bouaziz","doi":"10.1016/j.revmed.2023.04.210","DOIUrl":"https://doi.org/10.1016/j.revmed.2023.04.210","url":null,"abstract":"","PeriodicalId":94122,"journal":{"name":"La Revue de medecine interne","volume":"107 1","pages":"A237 - A238"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82248414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Les patients sous traitement immusuppresseurs ont-ils une réponse humorale vaccinale anti-SARS-cov 2 réduite ? 接受免疫抑制治疗的患者是否降低了抗sars -cov 2疫苗体液反应?
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.193
R. Bourguiba, K. Dridi, M. Ayari, M. Boudokhane, I. Abdelaali, T. Jomni, M. H. Douggui, S. Bellakhal
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引用次数: 0
Auto-immunité persistante après COVID-19 : étude de cohorte prospective monocentrique COVID-19后持续自身免疫:单中心前瞻性队列研究
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.354
V. Salle, D. Basille, M. Auquier, C. Lateur, G. Bourdenet, B. Gubler, S. Devaux, A. Galmiche, V. Jounieaux, C. Andréjak
{"title":"Auto-immunité persistante après COVID-19 : étude de cohorte prospective monocentrique","authors":"V. Salle, D. Basille, M. Auquier, C. Lateur, G. Bourdenet, B. Gubler, S. Devaux, A. Galmiche, V. Jounieaux, C. Andréjak","doi":"10.1016/j.revmed.2023.04.354","DOIUrl":"https://doi.org/10.1016/j.revmed.2023.04.354","url":null,"abstract":"","PeriodicalId":94122,"journal":{"name":"La Revue de medecine interne","volume":"36 1","pages":"A124 - A125"},"PeriodicalIF":0.0,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"75362742","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Suivi à 6 mois d’une cohorte de patients immunodéprimés en médecine interne bénéficiant d’une prophylaxie préexposition au SARS-CoV2 par tixagevimab/cilgavimab 对接受tixagevimab/cilgavimab SARS-CoV2暴露前预防的内科免疫抑制患者进行6个月随访
La Revue de medecine interne
Pub Date : 2023-06-01 DOI: 10.1016/j.revmed.2023.04.181
M. Liagre, J. Chambord, M. Lahouati, I. Crubezy, S. Djabarouti, E. Lazaro
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引用次数: 0
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