Pub Date : 2024-05-20eCollection Date: 2024-01-01DOI: 10.18632/oncoscience.601
Tetsuhiro Horie, Eiichi Hinoi
{"title":"Role of Erk5 expressed in bone marrow mesenchymal stem cells on bone homeostasis and its potential applications in cancer treatment.","authors":"Tetsuhiro Horie, Eiichi Hinoi","doi":"10.18632/oncoscience.601","DOIUrl":"10.18632/oncoscience.601","url":null,"abstract":"","PeriodicalId":94164,"journal":{"name":"Oncoscience","volume":"11 ","pages":"45-46"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11104408/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-20eCollection Date: 2024-01-01DOI: 10.18632/oncoscience.602
Gregory L Guzik, Ankit Mangla
{"title":"Primary hepatic angiosarcoma: Treatment options for a rare tumor.","authors":"Gregory L Guzik, Ankit Mangla","doi":"10.18632/oncoscience.602","DOIUrl":"10.18632/oncoscience.602","url":null,"abstract":"","PeriodicalId":94164,"journal":{"name":"Oncoscience","volume":"11 ","pages":"47-48"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11104409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-20eCollection Date: 2024-01-01DOI: 10.18632/oncoscience.603
Richard L J Qiu, Chih-Wei Chang, Xiaofeng Yang
{"title":"Deep learning-assisted lesion segmentation in PET/CT imaging: A feasibility study for salvage radiation therapy in prostate cancer.","authors":"Richard L J Qiu, Chih-Wei Chang, Xiaofeng Yang","doi":"10.18632/oncoscience.603","DOIUrl":"10.18632/oncoscience.603","url":null,"abstract":"","PeriodicalId":94164,"journal":{"name":"Oncoscience","volume":"11 ","pages":"49-50"},"PeriodicalIF":0.0,"publicationDate":"2024-05-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11104407/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-05-06eCollection Date: 2024-01-01DOI: 10.18632/oncoscience.600
Xiaoling Li, Ping Mu
{"title":"Restoring our ubiquitination machinery to overcome resistance in cancer therapy.","authors":"Xiaoling Li, Ping Mu","doi":"10.18632/oncoscience.600","DOIUrl":"10.18632/oncoscience.600","url":null,"abstract":"","PeriodicalId":94164,"journal":{"name":"Oncoscience","volume":"11 ","pages":"43-44"},"PeriodicalIF":0.0,"publicationDate":"2024-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11073315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140869693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-25DOI: 10.18632/oncoscience.599
J. K. Nag, Amnon Hoffman, Chaim Gilon, Beatrice Uziely, R. Bar-Shavit
{"title":"PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs","authors":"J. K. Nag, Amnon Hoffman, Chaim Gilon, Beatrice Uziely, R. Bar-Shavit","doi":"10.18632/oncoscience.599","DOIUrl":"https://doi.org/10.18632/oncoscience.599","url":null,"abstract":"","PeriodicalId":94164,"journal":{"name":"Oncoscience","volume":"18 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140658506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-04-22DOI: 10.18632/oncoscience.597
Rafael Parra-Medina
{"title":"Exploring oncogenic driver molecular alterations in Hispanic/Latin American cancer patients: A call for enhanced molecular understanding","authors":"Rafael Parra-Medina","doi":"10.18632/oncoscience.597","DOIUrl":"https://doi.org/10.18632/oncoscience.597","url":null,"abstract":"","PeriodicalId":94164,"journal":{"name":"Oncoscience","volume":"11 24","pages":"34 - 35"},"PeriodicalIF":0.0,"publicationDate":"2024-04-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140674016","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-02-09eCollection Date: 2024-01-01DOI: 10.18632/oncoscience.595
Paul Dent
{"title":"A very long and winding road: developing novel therapeutics for metastatic tumors.","authors":"Paul Dent","doi":"10.18632/oncoscience.595","DOIUrl":"https://doi.org/10.18632/oncoscience.595","url":null,"abstract":"","PeriodicalId":94164,"journal":{"name":"Oncoscience","volume":"11 ","pages":"32-33"},"PeriodicalIF":0.0,"publicationDate":"2024-02-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10856472/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139725518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-03eCollection Date: 2024-01-01DOI: 10.18632/oncoscience.593
Mikhail V Blagosklonny
In January 2023, diagnosed with numerous metastases of lung cancer in my brain, I felt that I must accomplish a mission. If everything happens for a reason, my cancer, in particular, I must find out how metastatic cancer can be treated with curative intent. This is my mission now, and the reason I was ever born. In January 2023, I understood the meaning of life, of my life. I was born to write this article. In this article, I argue that monotherapy with targeted drugs, even when used in sequence, cannot cure metastatic cancer. However, preemptive combinations of targeted drugs may, in theory, cure incurable cancer. Also, I share insights on various topics, including rapamycin, an anti-aging drug that can delay but not prevent cancer, through my personal journey.
{"title":"My battle with cancer. Part 1.","authors":"Mikhail V Blagosklonny","doi":"10.18632/oncoscience.593","DOIUrl":"10.18632/oncoscience.593","url":null,"abstract":"<p><p>In January 2023, diagnosed with numerous metastases of lung cancer in my brain, I felt that I must accomplish a mission. If everything happens for a reason, my cancer, in particular, I must find out how metastatic cancer can be treated with curative intent. This is my mission now, and the reason I was ever born. In January 2023, I understood the meaning of life, of my life. I was born to write this article. In this article, I argue that monotherapy with targeted drugs, even when used in sequence, cannot cure metastatic cancer. However, preemptive combinations of targeted drugs may, in theory, cure incurable cancer. Also, I share insights on various topics, including rapamycin, an anti-aging drug that can delay but not prevent cancer, through my personal journey.</p>","PeriodicalId":94164,"journal":{"name":"Oncoscience","volume":"11 ","pages":"1-14"},"PeriodicalIF":0.0,"publicationDate":"2024-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10765422/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139379085","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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