Skinmed最新文献

A 64-year-old man participated in a 13.1-mile half marathon in San Diego, CA on April 23, 2023. The ambient temperature when he started the race was 54°F, which increased to 64°F on his completing the race 3 hours and 58 minutes later. Both of his hands and their digits started swelling after the first hour of running. They progressively became larger during the remainder of the race; a positive fist sign developed and the patient could not close his hands into a fist (Figure 1). Neither pruritus, swelling at any other site, nor angioedema was reported.

A 53-year-old woman presented with an eruption on her face and body for 2 weeks that had developed first on the face before spreading to the trunk and extremities. There was burning with sunlight exposure. Her medical conditions included diabetes mellitus, vitamin D deficiency, and hyperlipidemia. Her treatment for the past 4 years included metformin, saxagliptin, atorvastatin, vitamin B12, vitamin D, lansoprazole, and aspirin. Because atorvastatin did not control her lipids, fenofibrate was prescribed. At 3 months, she developed photodermatitis on the sun-exposed areas of her skin and also on sun-covered areas of the chest and back. Examination showed facial erythematous scaly plaques and multiple scaly annular erythematous plaques on her trunk and extremities (Figure 1). Methylprednisolone aceponate ointment, pimecrolimus ointment 0.1%, and sunblock were prescribed. Her facial eruption was only minimally lessened, while the dermatitis worsened on the trunk, arms, and legs.

Normal human life expectancy has increased; hence, growing interest in the field of skin quality is observed. Peels are common medical devices that stimulate new skin growth and improve texture. Injectable hyaluronic acid (HA)-based products act by replacing fragmented collagen. HA skin boosting is a new technique that is able to reduce aging indicators. The aim of this study was to evaluate the efficacy and safety of a multi-acid superficial peel combined with an HA skin booster to improve quality of the skin. We conducted a prospective study with patients presenting hyperpigmentation, skin dryness, loss of elasticity, or fine lines. The participants were required to apply either peel or booster treatment during an attack phase and during the followed maintenance phase. Subjective and objective evaluations were performed to assess clinical outcomes (i.e., skin hydration, firmness, and brightness). A total of 16 subjects participated in the study. We observed a higher satisfaction at the end of the treatment, compared to the baseline, for each of the three skin qualities (P < 0.0001). Similarly, analysis of physicians' global assessment scores demonstrated that physicians detected higher scores at the end of the study, compared to the baseline (P < 0.0001). Our study demonstrated the synergistic effect of a multi-acid superficial peel combined with HA skin boosting to improve skin appearance.

A relative paucity of published papers is observed regarding racial and ethnic disparities in cutaneous T cell lymphoma (CTCL). Although CTCL is a rare condition, the poor outcomes associated with this condition underscore the need to understand and address any existing care inequities. Recently, a growing body of literature has attempted to identify racial disparities in CTCL in terms of the overall survival, stage at presentation, time to initiate treatment, and complication rate. Some progress has been made in understanding the underlying causes of such disparities, with some proposing the biologic and genetic differences between Caucasian and black patients, others proposing that environmental exposure to chemicals, such as benzene, may predispose certain populations to the disease, and still others suggesting that other factors related to socioeconomic status, such as insurance type, may play a role. We review what is known about racial and ethnic differences in clinical presentations, existing health disparities, key hypotheses regarding drivers of these trends, and actionable strategies to address these disparities.