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A Comparison of the Marginal and Internal Fit of Temporary Crown Restorations Manufactured with Additive and Subtractive Techniques after Thermal Aging. 热老化后加减技术制造的临时冠修复体的边缘和内部配合比较。
IF 1.8 Pub Date : 2025-10-10 DOI: 10.11607/ijp.9491
Ayşe Lengerli Efe, Nuray Çapa Nuray Çapa
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引用次数: 0
Effects of Try-In Pastes and Polymerization Process of Resin Cements in Different Shades on the Final Color of 3D-Printed Resin-Based Restorations with Various Thicknesses. 不同色度树脂胶结物的试入膏体和聚合工艺对不同厚度树脂基3d打印修复体最终颜色的影响
IF 1.8 Pub Date : 2025-10-10 DOI: 10.11607/ijp.9479
Esra Kaynak Öztürk, Elif Yılmaz Biçer, Beyza Güney, Nagehan Aktaş, Merve Bankoğlu Güngör
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引用次数: 0
Prosthetic Complications in Implant-Related Dentistry: A Scoping Review of Selected Literature Over the Last 25 Years. 牙科种植体相关的假体并发症:过去25年的文献综述。
IF 1.8 Pub Date : 2025-10-02 DOI: 10.11607/ijp.9513
Busra Tosun

Purpose: To evaluate the global research landscape on dental prosthetic complications by identifying the most productive countries, institutions, authors, and journals. Additionally, it sought to highlight the most cited publications and commonly used keywords in the field.

Materials and methods: A comprehensive search was conducted in the Web of Science database on March 27, 2025, using the term 'dental prosthetic complications.' A total of 1665 English-language records (articles and reviews) published between January 2000 and December 2024 were analyzed. Bibliometric indicators-including publication year, citation count, country, institution, author, journal, and keywords-were evaluated using VOS viewer (v1.6.15) and Microsoft Excel.

Results: Research output increased substantially after 2010. Italy, the USA, and Germany ranked highest in publication volume, while Switzerland and Sweden showed the highest citation averages. The University of Bern was the most productive institution. Prolific authors included Marco Tallarico, Marco Esposito, Silvio Mario Meloni, and Niklaus P. Lang. Highly cited studies predominantly focused on complications in implant-supported restorations. Leading journals were The International Journal of Oral & Maxillofacial Implants, Clinical Oral Implants Research, Clinical Implant Dentistry and Related Research. Keyword analysis revealed that 'dental implants' and related terms remained central research themes.

Conclusions: The volume of research on dental prosthetic complications has grown considerably over the past two decades, particularly in relation to implant-based treatments. Since 2010, the growing number of publications and expanding international collaborations reflect rising scientific interest in this field. Recurrent complications continue to shape research priorities, highlighting the ongoing clinical significance of prosthetic complications.

目的:通过确定最具生产力的国家、机构、作者和期刊来评估牙科修复并发症的全球研究格局。此外,它还试图突出该领域被引用最多的出版物和常用关键词。材料和方法:2025年3月27日,在Web of Science数据库中进行了全面的搜索,使用术语“牙科修复并发症”。共分析了2000年1月至2024年12月期间发表的1665篇英文记录(文章和评论)。使用VOS viewer (v1.6.15)和Microsoft Excel对文献计量指标(包括出版年份、引文数量、国家、机构、作者、期刊和关键词)进行评估。结果:2010年以后,科研产出大幅增长。意大利、美国和德国的论文发表量最高,而瑞士和瑞典的平均引用量最高。伯尔尼大学是最具生产力的机构。多产的作家包括马可·塔拉里科、马可·埃斯波西托、西尔维奥·马里奥·梅洛尼和尼克劳斯·p·朗。高引用的研究主要集中在种植体支持修复的并发症上。主要期刊有《国际口腔颌面种植杂志》、《临床口腔种植研究》、《临床种植牙科及相关研究》。关键词分析显示,“种植牙”和相关术语仍然是研究的中心主题。结论:在过去的二十年中,关于义齿并发症的研究数量大幅增长,特别是与种植体治疗相关的研究。自2010年以来,越来越多的出版物和不断扩大的国际合作反映了人们对这一领域的科学兴趣日益浓厚。复发性并发症继续成为研究重点,突出了假肢并发症的持续临床意义。
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引用次数: 0
Comparative Analysis of Sagittal Condylar Inclination by Interocclusal Recordings, Panoramic Radiographs, and Computerized-Axiography Among Dentate Individuals. 有齿人群矢状突倾斜的牙间记录、全景x线片和计算机轴位摄影比较分析。
IF 1.8 Pub Date : 2025-10-02 DOI: 10.11607/ijp.9416
Duygu Karakis, Adam Erden Canan

Purpose: The present study aimed to compare sagittal condylar inclination (SCI) values obtained by three different methods-interocclusal wax recording, panoramic radiography, and electronic axiography (Cadiax-Compact 2).

Materials and methods: A total of 15 adults participated in this study. For the interocclusal recording, SCI was determined using protrusive interocclusal wax records, which were transferred to a semi-adjustable articulator. Panoramic radiographs were obtained and SCI values were measured by tracing the radiographic images. Extraoral tracings were recorded using a Cadiax-Compact 2. After a paraocclusal tray was fixed intraorally, each participant was instructed to perform three protrusive mandibular movements, and the average SCI values were calculated. The paired t-test was used to compare the SCI values of the right and left condyles. Pearson correlation analysis was performed to assess the relationship between the values obtained by the different methods, with a significance level set at p<0.05.

Results: No statistically significant difference was observed between right and left condyles for any of the three methods (p>0.05). The highest correlation was found between panoramic radiography and Cadiax-Compact 2, while moderate correlation was observed between interocclusal recordings and the other two methods. Interocclusal recordings yielded the lowest SCI values, while Cadiax-Compact 2 showed the highest.

Conclusion: Although panoramic radiography, and Cadiax-Compact 2 demonstrated strong correlation, interocclusal records showed moderate agreement and lower SCI values. However, considering the influence of functional movements, interocclusal recordings remain valuable for dentate patients. However, panoramic radiography can be a practical alternative in cases with limited neuromuscular control or a strong gag reflex.

目的:本研究旨在比较三种不同方法(牙间蜡记录、全景x线摄影和电子轴向摄影(Cadiax-Compact 2))获得的矢状突倾斜(SCI)值。材料与方法:共有15名成年人参与本研究。对于咬合记录,使用突出的咬合蜡记录来确定SCI,并将其转移到半可调节的关节器中。获得全景x线片,并通过追踪x线图像测量SCI值。使用Cadiax-Compact 2记录口外示踪。在口腔内固定咬合副托盘后,每位参与者被指示进行三次下颌突出运动,并计算平均SCI值。采用配对t检验比较左、右髁的SCI值。采用Pearson相关分析评价不同方法测量值之间的关系,并将显著性水平设为:结果:三种方法的左右髁间差异无统计学意义(p < 0.05)。全景x线摄影与Cadiax-Compact 2的相关性最高,而与其他两种方法的相关性中等。咬合记录的SCI值最低,而Cadiax-Compact 2最高。结论:尽管全景x线摄影与Cadiax-Compact 2表现出很强的相关性,但咬合记录显示中度一致,且SCI值较低。然而,考虑到功能运动的影响,咬合间记录对有齿患者仍然有价值。然而,在神经肌肉控制有限或呕吐反射强烈的情况下,全景x线摄影是一种实用的替代方法。
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引用次数: 0
Comparative Performance of Deep-Reasoning and Lightweight Large Language Models on Oral Implantology Multiple-Choice Questions. 深度推理和轻量级大语言模型在口腔种植学选择题中的比较表现。
IF 1.8 Pub Date : 2025-10-02 DOI: 10.11607/ijp.9504
Viet Anh Nguyen, Thi Quynh Trang Vuong, Van Hung Nguyen

Purpose: Large language models (LLMs) show promise in dental education, but their performance on specialized implantology knowledge is unclear. This study compared the accuracy and response times of six LLM configurations on an implantology MCQ dataset to guide optimal model selection.

Materials and methods: We administered 675 single-best-answer MCQs from a standard oral implantology question bank to six LLM setups in May 2025, including two OpenAI models (o3 and GPT-4o), two Microsoft Copilot modes (Deep and Quick, both based on o3-mini), and two Google Gemini variants (Flash and Pro). An independent assessor delivered questions in batches of ten using a uniform prompt, recorded each model's answers, and measured elapsed time per batch. Accuracy was the percentage of correct answers; response time was averaged across batches. χ² tests compared accuracy, and ANOVA compared response times.

Results: Accuracy varied significantly (p = 0.001). Gemini Pro (83.1%) and o3 Any blinded information will be available then. (82.4%) achieved the highest rates, outperforming GPT-4o (76.9%). Copilot Deep (77.8%) did not significantly exceed Copilot Quick (75.1%). Deep reasoning models (o3, Gemini Pro) averaged 4-5 s per batch, while lightweight variants (Copilot Quick, Gemini Flash, GPT-4o) responded in under 1 s (p < 0.001). All models uniformly failed questions requiring precise epidemiological or contraindication data.

Conclusions: Deep-reasoning LLMs deliver superior implantology MCQ accuracy at the cost of modestly longer inference times. Lightweight models offer near-instant responses with slightly lower accuracy. Aligning model choice to task complexity can optimize speed, cost, and diagnostic precision in implantology education and practice.

目的:大型语言模型(LLMs)在口腔教育中显示出良好的前景,但其在种植专业知识方面的表现尚不清楚。本研究比较了种植医学MCQ数据集上六种LLM配置的准确性和响应时间,以指导最佳模型选择。材料和方法:我们于2025年5月将标准口腔种植学题库中的675个单最佳答案mcq管理到六个LLM设置中,包括两个OpenAI模型(o3和gpt - 40),两个Microsoft Copilot模式(Deep和Quick,均基于o3-mini)和两个谷歌Gemini版本(Flash和Pro)。一个独立的评估员使用统一的提示,以10个为一个批次交付问题,记录每个模型的答案,并测量每个批次的运行时间。准确度是正确答案的百分比;每个批次的响应时间是平均的。χ 2检验比较准确率,方差分析比较反应时间。结果:准确度差异显著(p = 0.001)。Gemini Pro(83.1%)和o3届时将提供任何盲法信息。(82.4%)达到了最高的比率,优于gpt - 40(76.9%)。深层副驾驶(77.8%)没有明显超过快速副驾驶(75.1%)。深度推理模型(o3, Gemini Pro)平均每批4-5秒,而轻量级模型(Copilot Quick, Gemini Flash, gpt - 40)的响应时间低于1秒(p < 0.001)。所有的模型都没有解决需要精确流行病学或禁忌症数据的问题。结论:深度推理llm以较长的推理时间为代价提供了优越的种植学MCQ准确性。轻量级模型提供近乎即时的响应,精度略低。将模型选择与任务复杂性相匹配可以优化种植学教育和实践中的速度、成本和诊断精度。
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引用次数: 0
Association Between Edentulism and Chronic Disease in a Brazilian Older Adult Population. 巴西老年人口中无牙症与慢性疾病之间的关系
IF 1.8 Pub Date : 2025-10-02 DOI: 10.11607/ijp.9493
Ana Estéfanny Alves Cabral, Flávio Pereira Dos Santos Filho, Mariella Agostinho Lourenço, Bianca Souto de Medeiros Santos, Mateus Guedes Carvalho, Rafael Barroso Pazinatto, Fabíola Pessôa Pereira Leite, Laércio Almeida de Melo

Objective: The present study aimed to identify the chronic diseases present in Brazilian older adults that are associated with total edentulism.

Materials and methods: This study is characterized as cross-sectional and population-based. The database from the last National Health Survey (NHS) in Brazil was used to conduct it. The study population consisted of older adults aged 60 years or older. The chronic diseases analyzed were hypertension, diabetes, high cholesterol, heart disease, stroke, asthma, rheumatism, back problems, musculoskeletal disorders, depression, schizophrenia, chronic lung diseases, cancer and kidney failure. The Chi-squared test was initially used in the data analysis. Then, adjusted prevalence ratios were estimated using Poisson regression with robust variance, including all covariates in the model to identify chronic diseases associated with total edentulism.

Results: A total of 22,728 older adults were included. The prevalence of total edentulous older adults was 31.7%. The most prevalent chronic diseases in these completely edentulous older adults were hypertension (55.5%), back problems (29.1%) and high cholesterol (26.6%). Total edentulism in older adults was associated with the female sex (p<0.001), being older (p<0.001), illiterate (p<0.001), those who do not have health insurance (p<0.001), older adults who have hypertension (p<0.001), diabetes (p=0.004), and those who suffered a cerebrovascular accident (CVA) (p<0.001).

Conclusion: It is concluded that total edentulism in older adults is associated with worse socioeconomic conditions and with individuals who have hypertension, diabetes and who have suffered a stroke.

目的:本研究旨在确定巴西老年人中与全牙补牙症相关的慢性疾病。材料和方法:本研究以横断面和人群为基础。该调查使用了巴西上次全国健康调查(NHS)的数据库。研究人群包括60岁或以上的老年人。所分析的慢性病包括高血压、糖尿病、高胆固醇、心脏病、中风、哮喘、风湿病、背部问题、肌肉骨骼疾病、抑郁症、精神分裂症、慢性肺病、癌症和肾衰竭。数据分析最初采用卡方检验。然后,使用稳健方差的泊松回归估计校正患病率,包括模型中的所有协变量,以确定与全牙颌相关的慢性疾病。结果:共纳入22,728名老年人。无牙老年人总体患病率为31.7%。在这些完全无牙的老年人中,最常见的慢性疾病是高血压(55.5%)、背部问题(29.1%)和高胆固醇(26.6%)。结论:老年人全牙缺牙与社会经济条件差、高血压、糖尿病和脑卒中患者有关。
{"title":"Association Between Edentulism and Chronic Disease in a Brazilian Older Adult Population.","authors":"Ana Estéfanny Alves Cabral, Flávio Pereira Dos Santos Filho, Mariella Agostinho Lourenço, Bianca Souto de Medeiros Santos, Mateus Guedes Carvalho, Rafael Barroso Pazinatto, Fabíola Pessôa Pereira Leite, Laércio Almeida de Melo","doi":"10.11607/ijp.9493","DOIUrl":"https://doi.org/10.11607/ijp.9493","url":null,"abstract":"<p><strong>Objective: </strong>The present study aimed to identify the chronic diseases present in Brazilian older adults that are associated with total edentulism.</p><p><strong>Materials and methods: </strong>This study is characterized as cross-sectional and population-based. The database from the last National Health Survey (NHS) in Brazil was used to conduct it. The study population consisted of older adults aged 60 years or older. The chronic diseases analyzed were hypertension, diabetes, high cholesterol, heart disease, stroke, asthma, rheumatism, back problems, musculoskeletal disorders, depression, schizophrenia, chronic lung diseases, cancer and kidney failure. The Chi-squared test was initially used in the data analysis. Then, adjusted prevalence ratios were estimated using Poisson regression with robust variance, including all covariates in the model to identify chronic diseases associated with total edentulism.</p><p><strong>Results: </strong>A total of 22,728 older adults were included. The prevalence of total edentulous older adults was 31.7%. The most prevalent chronic diseases in these completely edentulous older adults were hypertension (55.5%), back problems (29.1%) and high cholesterol (26.6%). Total edentulism in older adults was associated with the female sex (p<0.001), being older (p<0.001), illiterate (p<0.001), those who do not have health insurance (p<0.001), older adults who have hypertension (p<0.001), diabetes (p=0.004), and those who suffered a cerebrovascular accident (CVA) (p<0.001).</p><p><strong>Conclusion: </strong>It is concluded that total edentulism in older adults is associated with worse socioeconomic conditions and with individuals who have hypertension, diabetes and who have suffered a stroke.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-16"},"PeriodicalIF":1.8,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215080","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The Impact of the Sintering Protocol on the Mechanical Properties of Hydrothermally-aged High-translucent Zirconia Materials. 烧结工艺对水热老化高半透明氧化锆材料力学性能的影响。
IF 1.8 Pub Date : 2025-10-02 DOI: 10.11607/ijp.9408
Secil Ozkan Ata, Sevgi Cetintas, Canan Akay, Emre Mumcu

Purpose: Aims to examine the high-speed sintering and conventional methods on To evaluate the effect of high-speed and conventional sintering on the biaxial flexural strength of high-translucent zirconia materials before and after artificial aging [Low temperature degradation (LTD)].

Materials and methods: A total of 156 zirconia samples A total of 156 zirconia specimens (disc-shaped, 12 mm diameter × 1.2 mm thickness) were prepared from three materials (4Y-TZP: Nacera DD-cube-ML-HT; 5Y-TZP: Nacera DD-cube-X2ML-HT; 6Y-TZP: Nacera Pearl-Q3-ML-HT; n = 52 each). Specimens were sintered using either a high-speed sintering protocol (1580 °C; n = 26) or a conventional sintering protocol (1450 °C; n = 26). The samples Specimens were artificially aged (LTD) (10 h, 134 °C; n = 13) or not aged (control group). Microhardness and biaxial strength of the samples were assessed. were measured. Phase composition was characterized using XRD Microhardness and biaxial flexural strength were measured, and phase composition was characterized using X-ray diffraction (XRD) with Rietveld refinement. ANOVA, post-hoc Tukey, The and Shapiro-Wilk tests were performed (p < 0.05). The survival probability was determined using Weibull analysis.

Results: Conventional sintering of 4Y-TZP and 5Y-TZP zirconia resulted in similar mechanical characteristics after LTD. The Weibull modulus of high-speed sintered zirconia specimens decreased following LTD. Among the groups, 4Y-TZP specimens exhibited the highest stability and strength, whereas 6Y-TZP showed the lowest performance. In Rietveld and XRD analyses, 4CL exhibited highest stability with an 80.7% t-phase ratio and 1709.79 MPa strength, while 6CL showed the lowest performance with 62.9% and 624.89 MPa.

Conclusion: Speed sintering and low-temperature decomposition LTD can lead to a degradation of the physical and mechanical properties of zirconia, potentially compromising its durability in clinical applications. An optimal sintering duration seems to enhance mechanical strength by preserving a high content of the tetragonal phase, thereby potentially extending the clinical lifespan. This situation underscores the necessity for more extensive research regarding the application of next-generation zirconia ceramics in clinical environments. Conventional sintering preserved higher flexural strength and phase stability compared to high-speed sintering under LTD conditions, and therefore appears more favorable for long-term performance.

目的:研究高速烧结和常规烧结对高半透明氧化锆材料人工老化前后双轴抗折强度的影响[低温降解(Low temperature degradation, LTD)]。采用4Y-TZP: Nacera DD-cube-ML-HT; 5Y-TZP: Nacera DD-cube-X2ML-HT; 6Y-TZP: Nacera Pearl-Q3-ML-HT,各n = 52)三种材料,共制备了156个圆盘状、直径12mm × 1.2 mm厚的氧化锆样品。试样采用高速烧结(1580°C, n = 26)或常规烧结(1450°C, n = 26)进行烧结。样品标本采用人工老化(LTD) (10 h, 134°C; n = 13)或不老化(对照组)。评估了样品的显微硬度和双轴强度。被测量。采用XRD对物相组成进行了表征,并测定了显微硬度和双轴抗折强度,采用Rietveld细化的x射线衍射(XRD)对物相组成进行了表征。方差分析、事后Tukey检验、The检验和Shapiro-Wilk检验(p < 0.05)。生存率采用威布尔分析。结果:4Y-TZP和5Y-TZP氧化锆经烧结后力学特性相似。高速烧结氧化锆试样的威布尔模量随LTD的减小而减小。其中,4Y-TZP的稳定性和强度最高,6Y-TZP的性能最低。在Rietveld和XRD分析中,4CL的稳定性最高,t相比为80.7%,强度为1709.79 MPa; 6CL的稳定性最低,t相比为62.9%,强度为624.89 MPa。结论:快速烧结和低温分解会导致氧化锆的物理力学性能下降,影响其临床应用的耐久性。最佳的烧结时间似乎可以通过保持高含量的四方相来提高机械强度,从而潜在地延长临床寿命。这种情况强调了对下一代氧化锆陶瓷在临床环境中的应用进行更广泛研究的必要性。与高速烧结相比,常规烧结在有限条件下保持了更高的抗折强度和相稳定性,因此表现出更有利的长期性能。
{"title":"The Impact of the Sintering Protocol on the Mechanical Properties of Hydrothermally-aged High-translucent Zirconia Materials.","authors":"Secil Ozkan Ata, Sevgi Cetintas, Canan Akay, Emre Mumcu","doi":"10.11607/ijp.9408","DOIUrl":"https://doi.org/10.11607/ijp.9408","url":null,"abstract":"<p><strong>Purpose: </strong>Aims to examine the high-speed sintering and conventional methods on To evaluate the effect of high-speed and conventional sintering on the biaxial flexural strength of high-translucent zirconia materials before and after artificial aging [Low temperature degradation (LTD)].</p><p><strong>Materials and methods: </strong>A total of 156 zirconia samples A total of 156 zirconia specimens (disc-shaped, 12 mm diameter × 1.2 mm thickness) were prepared from three materials (4Y-TZP: Nacera DD-cube-ML-HT; 5Y-TZP: Nacera DD-cube-X2ML-HT; 6Y-TZP: Nacera Pearl-Q3-ML-HT; n = 52 each). Specimens were sintered using either a high-speed sintering protocol (1580 °C; n = 26) or a conventional sintering protocol (1450 °C; n = 26). The samples Specimens were artificially aged (LTD) (10 h, 134 °C; n = 13) or not aged (control group). Microhardness and biaxial strength of the samples were assessed. were measured. Phase composition was characterized using XRD Microhardness and biaxial flexural strength were measured, and phase composition was characterized using X-ray diffraction (XRD) with Rietveld refinement. ANOVA, post-hoc Tukey, The and Shapiro-Wilk tests were performed (p < 0.05). The survival probability was determined using Weibull analysis.</p><p><strong>Results: </strong>Conventional sintering of 4Y-TZP and 5Y-TZP zirconia resulted in similar mechanical characteristics after LTD. The Weibull modulus of high-speed sintered zirconia specimens decreased following LTD. Among the groups, 4Y-TZP specimens exhibited the highest stability and strength, whereas 6Y-TZP showed the lowest performance. In Rietveld and XRD analyses, 4CL exhibited highest stability with an 80.7% t-phase ratio and 1709.79 MPa strength, while 6CL showed the lowest performance with 62.9% and 624.89 MPa.</p><p><strong>Conclusion: </strong>Speed sintering and low-temperature decomposition LTD can lead to a degradation of the physical and mechanical properties of zirconia, potentially compromising its durability in clinical applications. An optimal sintering duration seems to enhance mechanical strength by preserving a high content of the tetragonal phase, thereby potentially extending the clinical lifespan. This situation underscores the necessity for more extensive research regarding the application of next-generation zirconia ceramics in clinical environments. Conventional sintering preserved higher flexural strength and phase stability compared to high-speed sintering under LTD conditions, and therefore appears more favorable for long-term performance.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"1-27"},"PeriodicalIF":1.8,"publicationDate":"2025-10-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145215122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
505 EAO NEWS Volume 38, Number 5, 2025 EAO Master Diploma in Implant Dentistry. 505 EAO NEWS 38卷,第5期,2025年EAO种植牙科硕士文凭。
IF 1.8 Pub Date : 2025-09-25 DOI: 10.11607/ijp.2025.5.eao
Jan Cosyn, Christel Larsson, Helena Francisco
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引用次数: 0
Enhancing Removable Partial Denture Hygiene: Investigating Mucolytic Agents and Biocides for Disrupting Biofilms and Improving Antimicrobial Efficacy. 加强可摘局部义齿的卫生:研究用于破坏生物膜和提高抗菌效果的溶菌剂和杀菌剂。
IF 1.8 Pub Date : 2025-09-25 DOI: 10.11607/ijp.9133
Leonardo Guedes da Silva Moraes, Viviane de Cássia Oliveira, Ana Paula Macedo, Carolina Alves Freiria de Oliveira, Evandro Watanabe, Valéria Oliveira Pagnano

Purpose: To evaluate the antibiofilm action of 2.5 mg/mL peracetic acid (PA), 0.5 mg/mL cetylpyridinium chloride (CPC), and 160 mg/mL N-acetylcysteine (NAC) against multispecies biofilm of Streptococcus mutans, Staphylococcus aureus, Candida albicans, and Candida glabrata developed on surfaces of heat-polymerizing acrylic resin (AR) and cobalt-chromium (Co-Cr) alloy.

Materials and methods: A multispecies biofilm was grown on the surface of AR and Co-Cr specimens (Ø 12 × 3 mm). After biofilm maturation, the specimens were immersed in experimental solutions and evaluated through biofilm viability (CFU; n = 9), biofilm metabolic activity (XTT; n = 9), biofilm-covered areas (live/dead; n = 2), effects on the extracellular polymeric substance (EPS; n = 2), and biofilm morphology (n = 1). Data were analyzed by ANOVA and Tukey post-hoc test or Kruskal-Wallis followed by Dunn post-hoc test (α = .05).

Results: Overall, all evaluated solutions impacted biofilm viability. PA presented wider activity by reducing CFU of all microorganisms on both surfaces, XTT (P < .001) and live/dead (P < .001). NAC had a notorious effect in reducing the viability of bacteria without affecting the yeasts. NAC reduced XTT on AR (P = .006) and Co-Cr (P = .003) but did not reduce the aggregated biofilm layer. CPC had a distinct effect, being most effective in reducing CFU on AR compared to the Co-Cr surface. However, it did not influence XTT or the amount of residual aggregated biofilm.

Conclusions: PA provided the greatest antibiofilm action, while CPC and NAC showed intermediate action. Nonetheless, no solution was able to completely remove the biofilm adhered to the surfaces of heat-polymerizing AR and Co-Cr alloy.

目的:本研究评估了 2.5 mg/mL 过氧乙酸(PA)、0.5 毫克/毫升十六烷基氯化吡啶(CPC)和 160 毫克/毫升 N-乙酰半胱氨酸(NAC)对变异链球菌、金黄色葡萄球菌、白色念珠菌和白色念珠菌在热聚合丙烯酸树脂(AR)和钴铬合金(Co-Cr)表面形成的多菌种生物膜的抗生物膜作用:在丙烯酸树脂和钴铬合金试样(直径 12×3mm)表面生长多菌种生物膜。生物膜成熟后,将试样浸入实验溶液中,通过生物膜活力(CFU)(n=9)、生物膜代谢活性(XTT)(n=9)、生物膜覆盖面积(活/死)(n=2)、对胞外聚合物物质(EPS)的影响(n=2)和生物膜形态(n=1)进行评估。数据分析采用方差分析和 Tukey 后检验或 Kruskal-Wallis 后邓恩检验(α=.05):总体而言,所有评估的溶液都对生物膜的活力产生了影响。PA 具有更广泛的活性,能减少两种表面上所有微生物的 CFU,XTT(PConclusions):PA 的抗生物膜作用最大,而 CPC 和 NAC 的作用居中。不过,没有一种溶液能够完全清除附着在热聚合 AR 和 Co-Cr 合金表面的生物膜。
{"title":"Enhancing Removable Partial Denture Hygiene: Investigating Mucolytic Agents and Biocides for Disrupting Biofilms and Improving Antimicrobial Efficacy.","authors":"Leonardo Guedes da Silva Moraes, Viviane de Cássia Oliveira, Ana Paula Macedo, Carolina Alves Freiria de Oliveira, Evandro Watanabe, Valéria Oliveira Pagnano","doi":"10.11607/ijp.9133","DOIUrl":"10.11607/ijp.9133","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the antibiofilm action of 2.5 mg/mL peracetic acid (PA), 0.5 mg/mL cetylpyridinium chloride (CPC), and 160 mg/mL N-acetylcysteine (NAC) against multispecies biofilm of Streptococcus mutans, Staphylococcus aureus, Candida albicans, and Candida glabrata developed on surfaces of heat-polymerizing acrylic resin (AR) and cobalt-chromium (Co-Cr) alloy.</p><p><strong>Materials and methods: </strong>A multispecies biofilm was grown on the surface of AR and Co-Cr specimens (Ø 12 × 3 mm). After biofilm maturation, the specimens were immersed in experimental solutions and evaluated through biofilm viability (CFU; n = 9), biofilm metabolic activity (XTT; n = 9), biofilm-covered areas (live/dead; n = 2), effects on the extracellular polymeric substance (EPS; n = 2), and biofilm morphology (n = 1). Data were analyzed by ANOVA and Tukey post-hoc test or Kruskal-Wallis followed by Dunn post-hoc test (α = .05).</p><p><strong>Results: </strong>Overall, all evaluated solutions impacted biofilm viability. PA presented wider activity by reducing CFU of all microorganisms on both surfaces, XTT (P < .001) and live/dead (P < .001). NAC had a notorious effect in reducing the viability of bacteria without affecting the yeasts. NAC reduced XTT on AR (P = .006) and Co-Cr (P = .003) but did not reduce the aggregated biofilm layer. CPC had a distinct effect, being most effective in reducing CFU on AR compared to the Co-Cr surface. However, it did not influence XTT or the amount of residual aggregated biofilm.</p><p><strong>Conclusions: </strong>PA provided the greatest antibiofilm action, while CPC and NAC showed intermediate action. Nonetheless, no solution was able to completely remove the biofilm adhered to the surfaces of heat-polymerizing AR and Co-Cr alloy.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"559-569"},"PeriodicalIF":1.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142335529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Accuracy of Intraoral Scanning vs Analog Impression for Prostheses Supported by Multiple Implants in Long Edentulous Spans: A Comparative Clinical Study. 口腔内扫描与模拟印模在长无牙段多种植体支持修复中的准确性:一项比较临床研究。
IF 1.8 Pub Date : 2025-09-25 DOI: 10.11607/ijp.9180
Jie Ma, Binghua Zhang, Hao Song, Shuang Xu, Tiantian Chen, Tao Song

Purpose: To evaluate the accuracy of intraoral scanning (IOS) impressions for multiple implants by comparing them to analog impressions.

Materials and methods: Patients with three adjacent implants in partially edentulous arches were recruited. For each arch, IOS impressions were obtained. Using the analog splinted-impression technique, casts were obtained and scanned with an extraoral scanner. Using metrology software, the distances and angles between the implants were measured in all IOS and analog impression STL files. The absolute values of the distance and angular deviation were calculated and analyzed by comparing the two impression methods.

Results: A total of 34 patients with partially edentulous arches were enrolled. The distance deviation between the IOS and analog impressions was 85.09 ± 58.73 µm, which was significantly lower than the clinically acceptable threshold for error (150 µm; P < .001). The angular deviation was 0.515 ± 0.426 degrees. Distance deviations were significantly correlated with the interimplant distances (r = 0.384, P = .001) and angulations (r = 0.278, P = .022).

Conclusions: For prostheses supported by multiple implants in partially edentulous arches, the distance deviation between the IOS and analog impression was within the clinically acceptable range of misfit and increased with increasing interimplant distance and angulation.

目的:临床科学证据表明,在部分无牙弓多种植体支持的口腔内扫描(IOS)印模的准确性是有限的。本体内研究旨在通过与模拟印模的比较,评估多个植入物的IOS印模的准确性。材料和方法:选取部分无牙弓相邻种植3个种植体的患者。对于每个arch,我们都会获得IOS印象。使用模拟夹板印模技术,获得铸型并用口外扫描仪扫描。使用计量软件,在所有的IOS和模拟印象标准镶嵌语言文件中测量种植体之间的距离和角度。通过对两种压印方法的比较,计算并分析了距离和角偏差的绝对值。结果:入选34例部分无牙弓患者。IOS与模拟印模之间的距离偏差为85.09±58.73µm,显著低于临床可接受误差(150µm;P < 0.001)。角度偏差为0.515±0.426°。距离偏差与种植间距离(r = 0.384, P = 0.001)和种植角度(r = 0.278, P = 0.022)显著相关。结论:对于部分无牙弓的多种植体支持修复体,植入物与模拟印模之间的距离偏差在临床可接受的不匹配范围内,并且随着种植间距离和角度的增加而增加。
{"title":"Accuracy of Intraoral Scanning vs Analog Impression for Prostheses Supported by Multiple Implants in Long Edentulous Spans: A Comparative Clinical Study.","authors":"Jie Ma, Binghua Zhang, Hao Song, Shuang Xu, Tiantian Chen, Tao Song","doi":"10.11607/ijp.9180","DOIUrl":"10.11607/ijp.9180","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the accuracy of intraoral scanning (IOS) impressions for multiple implants by comparing them to analog impressions.</p><p><strong>Materials and methods: </strong>Patients with three adjacent implants in partially edentulous arches were recruited. For each arch, IOS impressions were obtained. Using the analog splinted-impression technique, casts were obtained and scanned with an extraoral scanner. Using metrology software, the distances and angles between the implants were measured in all IOS and analog impression STL files. The absolute values of the distance and angular deviation were calculated and analyzed by comparing the two impression methods.</p><p><strong>Results: </strong>A total of 34 patients with partially edentulous arches were enrolled. The distance deviation between the IOS and analog impressions was 85.09 ± 58.73 µm, which was significantly lower than the clinically acceptable threshold for error (150 µm; P < .001). The angular deviation was 0.515 ± 0.426 degrees. Distance deviations were significantly correlated with the interimplant distances (r = 0.384, P = .001) and angulations (r = 0.278, P = .022).</p><p><strong>Conclusions: </strong>For prostheses supported by multiple implants in partially edentulous arches, the distance deviation between the IOS and analog impression was within the clinically acceptable range of misfit and increased with increasing interimplant distance and angulation.</p>","PeriodicalId":94232,"journal":{"name":"The International journal of prosthodontics","volume":"0 0","pages":"511-517"},"PeriodicalIF":1.8,"publicationDate":"2025-09-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143367219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
The International journal of prosthodontics
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