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Bilateral anterior shoulder dislocation: A case report. 双侧肩关节前脱位:病例报告
Bedrettin Akar

Bilateral anterior shoulder dislocation (BASD) is a rare condition typically associated with a history of trauma. This case report presents a patient with BASD resulting from trauma and discusses treatment options. A 51-year-old male patient was admitted to the emergency department following a fall from a height. Radiographic examination revealed BASD and a comminuted intra-articular fracture of the distal end of the left radius. The patient did not have any other additional pathologies. After a preoperative evaluation, the patient was urgently taken to the operating room, where both shoulders underwent reduction using the Hippocratic maneuver under sedation anesthesia. Immediately after this procedure, the left wrist was reduced closed, and a penning-type external fixator was inserted under fluoroscopic guidance. Following the reductions, both shoulders were wrapped with a Velpeau bandage and immobilized. An elastic bandage was wrapped around the wrist. By the end of the third week, shoulder mobility exercises were initiated, with a gradual increase in the intensity of the exercises. The wrist fixator was removed in the fifth week after radiographic evaluations, followed by the initiation of passive and then active exercises. Given the rarity of BASD, it is crucial to obtain a detailed clinical history, conduct a comprehensive clinical examination, and perform detailed imaging studies-radiography, computed tomography, and magnetic resonance imaging to avoid overlooking such pathologies in emergency situations. Bilateral anterior shoulder dislocation is a pathology that results from major trauma. It is important to remember that this particular type of pathology may be accompanied by various other pathologies, such as fractures (of the tuberculum majus), rotator cuff injuries, and neurovascular injuries.

双侧肩关节前脱位(BASD)是一种罕见的疾病,通常与外伤史有关。本病例报告介绍了一名因外伤导致双侧肩关节前脱位的患者,并讨论了治疗方案。一名 51 岁的男性患者因高处坠落被送入急诊科。X光检查显示患者患有BASD,左桡骨远端关节内粉碎性骨折。患者没有其他病变。术前评估后,患者被紧急送入手术室,在镇静麻醉下使用希波克拉底手法对双肩进行了复位。手术结束后,立即对左手腕进行了闭合缩窄,并在透视引导下植入了潘宁型外固定器。缩小术后,用 Velpeau 绷带包裹并固定双肩。手腕处缠绕弹性绷带。第三周结束时,开始进行肩部活动练习,练习强度逐渐增加。第五周进行放射学评估后,移除腕部固定器,然后开始进行被动和主动锻炼。鉴于双侧肩关节前脱位的罕见性,获取详细的临床病史、进行全面的临床检查以及进行详细的影像学检查--射线照相术、计算机断层扫描和磁共振成像--以避免在紧急情况下忽略此类病症至关重要。双侧肩关节前脱位是一种由重大创伤引起的病理现象。重要的是要记住,这种特殊类型的病变可能伴有其他各种病变,如骨折(大结节骨折)、肩袖损伤和神经血管损伤。
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引用次数: 0
Intestinal choriocarcinoma without primary source: A diagnostic enigma. 无原发来源的肠绒毛膜癌:诊断之谜
Semra Tutcu Şahin, Pinar Solmaz Hasdemir, Ömer Atmış, Aygül Aliyeva

Intestinal choriocarcinoma is a very rare phenomenon. This is the first reported case of intestinal choriocarcinoma following an ectopic pregnancy. We report a 24 year-old woman who presented with severe abdominal pain, distension, and vomiting. She had a history of an ectopic pregnancy nine months prior. Emergent laparotomy exploration revealed abscess formation and obstructions at two sites in the small intestine, with unremarkable gynecological organs. The obstructed sections of the intestinal were excised and subsequently diagnosed as intestinal choriocarcinoma in histopathological evaluation. Postoperative positron emission tomography (PET) revealed a non-contrast-enhancing lesion on the small intestinal wall with increased metabolic activity consistent with healing tissue at the anastomosis site. No other primary focus and/or metastatic lesions were detected. Multi-agent chemotherapy was planned for the patient. No residual and/or recurrent tumoral lesions were detected on the PET scan at the one-year follow-up.

肠绒毛膜癌是一种非常罕见的现象。这是首例宫外孕后发生肠绒毛膜癌的病例。我们报告了一名 24 岁女性的病例,她出现剧烈腹痛、腹胀和呕吐。她在 9 个月前曾有过宫外孕病史。急诊剖腹探查发现脓肿形成,小肠两个部位梗阻,妇科器官无异常。肠梗阻部分被切除,随后在组织病理学评估中被诊断为肠绒毛膜癌。术后正电子发射断层扫描(PET)显示,小肠壁上有一个非造影剂增强的病灶,代谢活动增加,与吻合部位的愈合组织一致。未发现其他原发病灶和/或转移病灶。计划对患者进行多药化疗。在一年的随访中,PET 扫描未发现残留和/或复发的肿瘤病灶。
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引用次数: 0
Transanal evisceration of small intestines due to chronic rectal prolapse: Still an intriguing case. 慢性直肠脱垂导致小肠经肛门撕裂:仍然是一个耐人寻味的病例。
Nur Ramoglu, Ismail Ahmet Bilgin, Volkan Ozben, Bilgi Baca, Ismail Hamzaoglu, Tayfun Karahasanoglu

Evisceration of the small intestine from a perforated rectum is a rare condition, particularly seen in elderly women. We present a case involving an 83-year-old woman with a history of chronic rectal prolapse and no other comorbidities. The patient declined surgical intervention for her rectal prolapse, and one month later, she presented with evisceration of the small intestine from the anus. The intervention was a laparotomy followed by Hartmann's procedure, which is the most recommended procedure. No small bowel resection was necessary. Although the management of this case was adequate and timely, the patient did not survive. This case underscores that elective repair of rectal prolapse might prevent this very rare but potentially fatal complication of transanal small intestinal evisceration.

直肠穿孔导致小肠外翻是一种罕见病,尤其多见于老年妇女。我们介绍了一个病例,患者是一名 83 岁的妇女,有慢性直肠脱垂病史,无其他合并症。患者拒绝对直肠脱垂进行手术治疗,一个月后,她出现了小肠从肛门处撕裂的症状。患者接受了最推荐的哈特曼手术,即开腹手术。无需切除小肠。尽管对该病例的处理充分而及时,但患者还是没能存活下来。本病例强调,选择性修复直肠脱垂可能会避免这种非常罕见但可能致命的经肛门小肠撕裂并发症。
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引用次数: 0
Is there any effect of lidocaine on ischemia/reperfusion injury in testicular torsion? An experimental study. 利多卡因对睾丸扭转的缺血再灌注损伤有影响吗?一项实验研究。
Vildan Kölükçü, Mehtap Gürler Balta, Hakan Tapar, Tugba Karaman, Serkan Karaman, Velid Unsal, Fikret Gevrek, Kenan Yalçın, Fatih Fırat

Background: This experimental study aimed to evaluate the potential protective effects of lidocaine on ischemia-reperfusion injury resulting from testicular torsion/detorsion in rats.

Methods: A total of 18 male rats were randomized into three groups. Group 1 served as the control group. Group 2 was designed to evaluate testicular ischemia-reperfusion injury using a torsion/detorsion model. In Group 3, the treatment group, a similar ischemia-reperfusion model was used as in Group 2. Additionally, lidocaine at a dose of 15 mg/kg was administered intraperitoneally five minutes before reperfusion. Blood biochemical analyses and testicular histopathological evaluations were conducted.

Results: Blood biochemical analysis showed that malondialdehyde (MDA) and protein carbonyl (PC) levels were significantly higher in Group 2 compared to the other groups (p<0.001 and p=0.008, respectively). Proinflammatory cytokine levels, including interleu-kin-1 (IL-1), interleukin-6 (IL-6), and tumor necrosis factor-alpha (TNF-alpha), were lower in Group 3 than in Group 2 (p<0.001, p=0.007, and p=0.026, respectively). Antioxidant enzyme activities, including glutathione peroxidase (GSH-Px) and superoxide dismutase (SOD), were higher in Group 3 compared to Group 2 (p=0.005 and p=0.025, respectively). Histopathological evaluations revealed significant improvements in all testicular damage scores, including hemorrhage, edema, vasocongestion, and inflammation in Group 3 compared to Group 2 (p=0.015, p=0.035, p=0.015, and p=0.034, respectively). Additionally, there was a notable improvement in the Johnsen score in Group 3 compared to Group 2 (p=0.034).

Conclusion: Lidocaine, an effective local anesthetic, significantly alleviates the effects of testicular ischemia-reperfusion injury.

背景:本实验研究旨在评估利多卡因对大鼠睾丸扭转/脱落导致的缺血再灌注损伤的潜在保护作用:本实验研究旨在评估利多卡因对大鼠睾丸扭转/离断造成的缺血再灌注损伤的潜在保护作用:方法:将 18 只雄性大鼠随机分为三组。第 1 组为对照组。第 2 组旨在使用扭转/脱位模型评估睾丸缺血再灌注损伤。第 3 组为治疗组,采用与第 2 组类似的缺血再灌注模型。此外,在再灌注前五分钟腹腔注射 15 毫克/千克剂量的利多卡因。进行了血液生化分析和睾丸组织病理学评估:结果:血液生化分析显示,第 2 组的丙二醛(MDA)和蛋白质羰基(PC)水平明显高于其他组(p):利多卡因是一种有效的局麻药,能明显减轻睾丸缺血再灌注损伤的影响。
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引用次数: 0
Trans-syndesmotic fixation in supination external rotation type 4 injuries: Are intraoperative tests reliable? 经腱鞘固定治疗上翻外旋4型损伤:术中测试可靠吗?
Gürkan Çalışkan, Yunus Elmas, Orhun Çelik

Background: Ankle fractures occur due to a rotational mechanism. According to the Lauge-Hansen classification, supination-external rotation (SER) injuries are the most common type. Following osseous fixation, the evaluation and treatment of syndesmotic injuries in these injuries are controversial. This study aimed to evaluate the clinical, functional, and radiological results of trans-syndesmotic fixation using intraoperative tests in SER type 4 ankle injuries.

Methods: Ankle syndesmosis was intraoperatively evaluated using cotton/hook and manual external rotation stress tests in 64 patients with SER type 4 fracture dislocation injuries. These patients were divided into two groups: those treated with and without trans-syndesmotic fixation in addition to open reduction and internal fixation of the fractures. Ankle range of motion (ROM), American Orthopedic Foot and Ankle Society (AOFAS) Ankle-Hindfoot Score, and Olerud-Molander Ankle Score (OMAS), tibiofibular overlap, tibiofibular clear space, and joint arthritis based on the Kellgren-Lawrence (K-L) scale were evaluated.

Results: Median values of OMAS (Z=-3.92, p<0.001), AOFAS (Z=-4.31, p<0.001), and ROM (Z=-2.95, p=0.003) were higher in Group 1. There were no differences between the groups regarding tibiofibular overlap median values (Z=-0.59, p=0.0554), tibiofibular clear space (Z=-1.13, p=0.258), and Kellgren-Lawrence arthritis scale. Lack of posterior malleolus fixation was found to increase the risk of arthritis by 18.197 times, despite having trans-syndesmotic fixation, which was statistically significant (Confidence Interval, CI: 2.482-133.417, p=0.004) (Table 4).

Conclusion: Median values of OMAS, AOFAS, and ROM in patients without trans-syndesmotic fixation were lower. These results indicate that intraoperative tests may not provide entirely accurate results in SER type 4 injuries. Failure to detect a syndesmotic injury timely can result in instability. Therefore, we think that routine trans-syndesmotic fixation, as well as posterior malleolus fixation in SER type 4 ankle injuries, may improve outcomes.

背景:踝关节骨折是由于旋转机制造成的。根据劳格-汉森(Lauge-Hansen)的分类,上翻-外旋(SER)损伤是最常见的类型。在骨性固定后,这些损伤中联合肌损伤的评估和治疗仍存在争议。本研究旨在通过术中测试评估经巩膜固定术治疗 SER 第 4 型踝关节损伤的临床、功能和放射学效果:方法: 对 64 名 SER 4 型骨折脱位患者进行踝关节巩膜术中评估,使用棉花/钩和手动外旋应力测试。这些患者被分为两组:在骨折切开复位和内固定的基础上进行经巩膜固定治疗和未进行经巩膜固定治疗的患者。根据凯尔格伦-劳伦斯(K-L)量表对踝关节活动范围(ROM)、美国骨科足踝协会(AOFAS)踝关节-后足评分、奥勒德-莫兰德踝关节评分(OMAS)、胫腓骨重叠度、胫腓骨间隙和关节炎进行了评估:结果:OMAS 的中位值(Z=-3.92,p结论:未进行经腱鞘固定的患者的 OMAS、AOFAS 和 ROM 中位值较低。这些结果表明,术中测试可能无法为 SER 4 型损伤提供完全准确的结果。如果不能及时发现巩膜损伤,可能会导致不稳定。因此,我们认为对 SER 第 4 型踝关节损伤进行常规经巩膜固定和后踝骨固定可能会改善预后。
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引用次数: 0
Evaluation of the effects of thymoquinone on red blood cell deformability, morphology, and endothelial nitric oxide synthase (eNOS) synthesis in rat lower extremity ischemia-reperfusion injury. 评估胸腺醌对大鼠下肢缺血再灌注损伤中红细胞变形、形态和内皮一氧化氮合酶(eNOS)合成的影响。
Celalettin Gunay, Hakan Kartal, Ertan Demirdas, Bilgehan Savas Oz, Faruk Metin Comu, Gokhan Erol, Gokhan Arslan, Tayfun Ozdem, Tuna Demirkıran, Muharrem Emre Ozdaş, Isıl Ozdas, Yigit Tokgoz, Veli Can Ozdemir

Background: Erythrocyte deformability refers to the ability of erythrocytes to bend and twist as they pass through capillaries, which is crucial for tissue perfusion. This study aims to investigate the effects of Thymoquinone treatment on erythrocyte deformability in rats subjected to lower extremity ischemia-reperfusion injury.

Methods: The study was conducted on Wistar albino rats weighing 400-450 g. The rats were randomly divided into five groups: the control group (C), in which no treatment was applied; the group that received dimethyl sulfoxide (DMSO) as a solvent; the group subjected to 90 minutes of ischemia followed by 90 minutes of reperfusion in the main femoral artery of the lower extremity (IR); the Thymoquinone control group (TQ-C), in which the effects of Thymoquinone alone were examined; and the group that received intraperitoneal Thymoquinone one hour before the ischemia-reperfusion procedure (IR+TQ). At the end of the procedure, intracardiac blood was collected from the rats, and May-Grunwald and Giemsa (MGG) staining, endothelial nitric oxide synthase (eNOS), and erythrocyte deformability indexes were measured.

Results: The study results showed significant differences. Erythrocyte deformability was statistically significantly improved in the group that received Thymoquinone before ischemia-reperfusion compared to the group subjected to ischemia-reperfusion only. Mor-phological changes in erythrocytes were also statistically significantly better in the IR+TQ group than in the IR group. Immunohisto-chemical eNOS staining revealed that eNOS activity in the IR group was lower than in the IR+TQ group.

Conclusion: Our study demonstrates that Thymoquinone treatment administered before ischemia exerts protective effects against erythrocyte deformation and morphological deterioration by increasing eNOS activity.

背景:红细胞变形性是指红细胞通过毛细血管时弯曲和扭曲的能力,这对组织灌注至关重要。本研究旨在探讨胸腺醌治疗对下肢缺血再灌注损伤大鼠红细胞变形能力的影响:研究对象为体重400-450克的Wistar白化大鼠。大鼠随机分为五组:对照组(C),不进行任何治疗;接受二甲基亚砜(DMSO)作为溶剂的组;下肢股主干动脉缺血 90 分钟后再灌注 90 分钟的组(IR);胸腺醌对照组(TQ-C),该组只研究胸腺醌的作用;以及在缺血再灌注手术前一小时腹腔注射胸腺醌的一组(IR+TQ)。在缺血再灌注过程结束后,采集大鼠的心内血液,测定梅-格氏和吉氏(MGG)染色、内皮一氧化氮合酶(eNOS)和红细胞变形指数:结果:研究结果显示存在明显差异。缺血再灌注前服用胸腺醌的组与仅接受缺血再灌注的组相比,红细胞变形性在统计学上有明显改善。红细胞的形态学变化在统计学上也是IR+胸腺醌组明显优于IR组。免疫组化 eNOS 染色显示,IR 组的 eNOS 活性低于 IR+TQ 组:我们的研究表明,缺血前服用胸腺醌可通过提高 eNOS 活性,对红细胞变形和形态学恶化起到保护作用。
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引用次数: 0
The effects of zinc sulfate mineral supplementation on Achilles tendon healing in rats. 补充硫酸锌矿物质对大鼠跟腱愈合的影响
Yiğit Önaloğlu, Ender Alagöz, Mahsum Solmaz, Nilsen Yıldırım Erdoğan, Metehan Demirkol, Bedri Onur Küçükyıldırım

Background: The Achilles tendon is the most commonly injured and ruptured tendon in the body and typically occurs during participation in sports or recreational activities in men between 30 and 50 years of age. Treatment options for Achilles tendon rupture include conservative and surgical approaches. Conservative treatment is associated with a higher risk of rerupture, while surgical treatment carries a risk of wound site complications. Generally, both methods result in a prolonged tendon healing time. Studies are ongoing to identify biomolecules that aid tendon repair. The main objective of our study is to investigate the effects of zinc sulfate (ZnSO4) mineral supplementation on Achilles tendon healing in rats.

Methods: Forty-eight female Sprague-Dawley rats were divided into four equal groups (C-15, C-30, ZnSO4-15, and ZnSO4-30) after standard Achilles tendon repair surgery. The ZnSO4-15 and ZnSO4-30 groups received an oral zinc sulfate monohydrate solution (50 mg/kg/day) for 15 and 30 days, respectively. The C-15 and C-30 groups were given 1 mL of distilled water per day orally during the experimental periods. Rats were sacrificed on the 15th and 30th day depending on their groups, and the healing of the operated tendons was evaluated using Movin and Bonar histopathologic scoring. For biomechanical analyses, the operated and intact Achilles tendons of all groups were removed, and tensile tests were performed to determine the tensile strength and toughness values for each tendon.

Results: Movin and Bonar scores were significantly lower in the ZnSO4-15 group than in the C-15 group and in the ZnSO4-30 group than in the C-30 group (p<0.05). Although we did not find the biomechanical results statistically significant, the intact tendons of the ZnSO4-15 group exhibited higher toughness than those of the C-15 group, and the tensile strength and toughness values of the operated and intact tendons of the ZnSO4-30 group were also higher than those of the C-30 group.

Conclusion: Zinc sulfate monohydrate mineral supplementation had histopathologically positive effects on the proliferation and remodeling stages of Achilles tendon healing and may biomechanically benefit both operated and intact tendons.

背景:跟腱是人体中最常见的损伤和断裂肌腱,通常发生在 30 至 50 岁的男性参加体育或娱乐活动期间。跟腱断裂的治疗方法包括保守治疗和手术治疗。保守治疗再次断裂的风险较高,而手术治疗则存在伤口部位并发症的风险。一般来说,这两种方法都会导致肌腱愈合时间延长。目前正在进行研究,以确定有助于肌腱修复的生物分子。我们研究的主要目的是调查补充硫酸锌(ZnSO4)矿物质对大鼠跟腱愈合的影响:方法:标准跟腱修复手术后,48 只雌性 Sprague-Dawley 大鼠被分为四个相同的组别(C-15、C-30、ZnSO4-15 和 ZnSO4-30)。ZnSO4-15 组和 ZnSO4-30 组分别口服一水硫酸锌溶液(50 毫克/千克/天)15 天和 30 天。C-15组和C-30组在实验期间每天口服1毫升蒸馏水。根据组别不同,大鼠分别在第 15 天和第 30 天被处死,并使用 Movin 和 Bonar 组织病理学评分法评估手术肌腱的愈合情况。为了进行生物力学分析,移除所有组的手术肌腱和完整跟腱,并进行拉伸试验,以确定每条肌腱的拉伸强度和韧性值:结果:ZnSO4-15组的Movin和Bonar评分明显低于C-15组,ZnSO4-30组的Movin和Bonar评分明显低于C-30组(p结论:一水硫酸锌矿物质补充剂对跟腱愈合的增殖和重塑阶段具有组织病理学上的积极影响,可能对手术肌腱和完好肌腱都有生物力学上的益处。
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引用次数: 0
Traumatic multiple-level continuous and noncontinuous thoracolumbar spinal fractures management in adult patients: A single-center experience. 成年患者创伤性多发连续性和非连续性胸腰椎骨折的治疗:单中心经验。
Çağlar Türk, Nail Ozdemir

Background: This study aimed to describe our clinical experience with surgical approaches and patient management for traumatic multiple-level continuous and noncontinuous thoracolumbar spinal fractures.

Methods: We retrospectively evaluated patients with continuous and noncontinuous multiple-level thoracolumbar fractures who were operated on by the same surgical team from 2019 to 2021. These patients were divided into two groups: Group 1 (n=12, continuous fractures) and Group 2 (n=14, noncontinuous fractures). We assessed the patients' age, gender, fracture levels, fracture type, classification according to the AO (Arbeitsgemeinschaft für Osteosynthesefragen) Spine Thoracolumbar Fracture Classification, status of posterior ligament damage, presence of additional traumatic pathology, status of decompression via laminectomy, levels of stabilization and fusion, preoperative and postoperative neurological status, presence of cervical trauma, duration of operation, amount of blood loss, duration of hospitalization, and lordosis and kyphosis angles in terms of fusion status and postoperative follow-up over two years. The study excluded patients over the age of 65, those with single-level fractures, and pathological fractures caused by osteoporosis, infection, or spinal tumors.

Results: Gender, age, neurological status, application of laminectomy, surgical complications, status of cervical fracture, duration of operation, amount of blood loss, duration of hospitalization, lordosis, and kyphosis angles were uniformly distributed between the groups. All patients underwent fusions, ranging from three to eight, with a median of two (range 2-4) fracture levels, and a median of five instrumented vertebrae, ranging from four to seven. Significant differences between the two groups were observed in terms of operation duration (p=0.001), blood loss (p=0.010), duration of hospitalization (p=0.003), number of fusions (p<0.001), and instrumented vertebral segments (p=0.011).

Conclusion: Thus, a surgical approach involving decompression, vertebral fusion screws, allografts, and bone substitutes can enhance surgical outcomes for patients with continuous and noncontinuous vertebral fractures.

背景:本研究旨在描述我们对创伤性多水平连续性和非连续性胸腰椎骨折的手术方法和患者管理的临床经验:本研究旨在描述我们在创伤性多水平连续性和非连续性胸腰椎骨折的手术方法和患者管理方面的临床经验:我们回顾性评估了2019年至2021年由同一手术团队进行手术的连续性和非连续性多水平胸腰椎骨折患者。这些患者被分为两组:第一组(12 人,连续骨折)和第二组(14 人,非连续骨折)。我们评估了患者的年龄、性别、骨折程度、骨折类型、AO(Arbeitsgemeinschaft für Osteosynthesefragen)脊柱胸腰椎骨折分类、后韧带损伤情况、是否存在其他创伤性病变、椎板切除减压情况、稳定和融合程度、术前和术后神经状况、是否有颈椎创伤、手术时间、失血量、住院时间、融合状况下的前凸和后凸角度以及术后两年的随访情况。研究排除了 65 岁以上的患者、单发骨折患者以及由骨质疏松症、感染或脊柱肿瘤引起的病理性骨折患者:两组患者的性别、年龄、神经系统状况、椎板切除术的应用、手术并发症、颈椎骨折状况、手术时间、失血量、住院时间、脊柱前凸和后凸角度分布一致。所有患者都接受了融合术,融合范围从 3 到 8,骨折水平中位数为 2(范围 2-4),椎体器械中位数为 5(范围 4-7)。两组患者在手术时间(P=0.001)、失血量(P=0.010)、住院时间(P=0.003)、融合次数(P=0.003)方面存在显著差异:因此,采用减压、椎体融合螺钉、同种异体材料和骨替代物的手术方法可以提高连续性和非连续性椎体骨折患者的手术效果。
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引用次数: 0
Comparative study of imaging features in uncomplicated and complicated acute appendicitis. 无并发症急性阑尾炎和并发症急性阑尾炎影像特征对比研究。
Osman Şimşek, Sabri Şirolu, Yağmur Özkan Irmak, Rauf Hamid, Sefa Ergun, Nuray Kepil, Onur Tutar

Background: Acute appendicitis is a common cause of acute abdominal pain necessitating surgical intervention. While the traditional treatment has been urgent appendectomy, recent studies suggest that an antibiotics-first approach can be safe for uncomplicated cases. Classifying appendicitis into uncomplicated and complicated categories is crucial for guiding treatment decisions and predicting patient outcomes. This study aims to evaluate the distinct imaging findings associated with uncomplicated appendicitis and its complicated subtypes-phlegmonous, gangrenous, and perforated appendicitis-to aid in differential diagnosis.

Methods: This retrospective observational study was conducted from January 2014 to December 2023 and included 1,250 patients (492 women, 758 men) who underwent an appendectomy with available pathology results. After excluding 56 patients with normal pathology, 52 with non-appendicitis pathologies, and 48 with inaccessible computed tomography (CT) images, 1,094 patients were analyzed. CT images were evaluated for appendiceal diameter, wall thickness, cecal wall thickness, periappendiceal fat stranding, effusion, lymphadenopathy, intraluminal and free periappendiceal air, mucosal hyperenhancement, and the presence of appendicolith.

Results: The diameter of the appendix, along with the presence of periappendiceal air, effusion, and intraluminal appendicolith, were significantly higher in the perforated appendicitis group compared to other groups (p<0.05). Periappendiceal fat stranding, evaluated as a binary variable, did not show significant differences among the groups. Appendiceal wall thickness was higher in the perforated group and lower in the non-perforated gangrenous group compared to the uncomplicated group (p<0.05). No significant correlation was found for mucosal hyperenhancement between the appendicitis subgroups. Intraluminal air, though normal in a healthy appendix, was a specific predictor of complicated appendicitis when combined with other findings.

Conclusion: This study provides a detailed analysis of distinct imaging findings associated with uncomplicated and complicated appendicitis. Key differentiators such as appendiceal diameter, periappendiceal air, effusion, and intraluminal appendicolith are crucial for accurate diagnosis. The findings highlight the importance of these parameters in distinguishing various types of appendicitis, offering valuable insights for clinical practice. Future prospective studies and advanced imaging techniques are needed to validate these findings and enhance the diagnosis and management of acute appendicitis and its complications.

背景:急性阑尾炎是导致急性腹痛的常见原因,必须进行手术治疗。虽然传统的治疗方法是紧急阑尾切除术,但最近的研究表明,对于不复杂的病例,先用抗生素治疗是安全的。将阑尾炎分为不复杂和复杂两类对于指导治疗决策和预测患者预后至关重要。本研究旨在评估与无并发症阑尾炎及其复杂亚型--痰性、坏疽性和穿孔性阑尾炎--相关的不同影像学发现,以帮助鉴别诊断:这项回顾性观察研究于 2014 年 1 月至 2023 年 12 月进行,共纳入 1250 名接受阑尾切除术并有病理结果的患者(女性 492 人,男性 758 人)。在排除了 56 名病理结果正常的患者、52 名非阑尾炎病理结果正常的患者和 48 名无法获得计算机断层扫描(CT)图像的患者后,共对 1094 名患者进行了分析。对 CT 图像的阑尾直径、壁厚、盲肠壁厚、阑尾周围脂肪层、渗出物、淋巴结病、阑尾腔内和阑尾周围游离空气、粘膜增生以及阑尾结石的存在进行了评估:结果:与其他组别相比,穿孔性阑尾炎组的阑尾直径、阑尾周围空气、渗出物和腔内阑尾结石均显著增大(p):本研究详细分析了与非复杂性和复杂性阑尾炎相关的不同影像学结果。阑尾直径、阑尾周围空气、渗出物和腔内阑尾结石等关键鉴别指标对于准确诊断至关重要。研究结果强调了这些参数在区分各种类型阑尾炎方面的重要性,为临床实践提供了宝贵的见解。未来需要前瞻性研究和先进的成像技术来验证这些发现,并加强对急性阑尾炎及其并发症的诊断和管理。
{"title":"Comparative study of imaging features in uncomplicated and complicated acute appendicitis.","authors":"Osman Şimşek, Sabri Şirolu, Yağmur Özkan Irmak, Rauf Hamid, Sefa Ergun, Nuray Kepil, Onur Tutar","doi":"10.14744/tjtes.2024.50363","DOIUrl":"10.14744/tjtes.2024.50363","url":null,"abstract":"<p><strong>Background: </strong>Acute appendicitis is a common cause of acute abdominal pain necessitating surgical intervention. While the traditional treatment has been urgent appendectomy, recent studies suggest that an antibiotics-first approach can be safe for uncomplicated cases. Classifying appendicitis into uncomplicated and complicated categories is crucial for guiding treatment decisions and predicting patient outcomes. This study aims to evaluate the distinct imaging findings associated with uncomplicated appendicitis and its complicated subtypes-phlegmonous, gangrenous, and perforated appendicitis-to aid in differential diagnosis.</p><p><strong>Methods: </strong>This retrospective observational study was conducted from January 2014 to December 2023 and included 1,250 patients (492 women, 758 men) who underwent an appendectomy with available pathology results. After excluding 56 patients with normal pathology, 52 with non-appendicitis pathologies, and 48 with inaccessible computed tomography (CT) images, 1,094 patients were analyzed. CT images were evaluated for appendiceal diameter, wall thickness, cecal wall thickness, periappendiceal fat stranding, effusion, lymphadenopathy, intraluminal and free periappendiceal air, mucosal hyperenhancement, and the presence of appendicolith.</p><p><strong>Results: </strong>The diameter of the appendix, along with the presence of periappendiceal air, effusion, and intraluminal appendicolith, were significantly higher in the perforated appendicitis group compared to other groups (p<0.05). Periappendiceal fat stranding, evaluated as a binary variable, did not show significant differences among the groups. Appendiceal wall thickness was higher in the perforated group and lower in the non-perforated gangrenous group compared to the uncomplicated group (p<0.05). No significant correlation was found for mucosal hyperenhancement between the appendicitis subgroups. Intraluminal air, though normal in a healthy appendix, was a specific predictor of complicated appendicitis when combined with other findings.</p><p><strong>Conclusion: </strong>This study provides a detailed analysis of distinct imaging findings associated with uncomplicated and complicated appendicitis. Key differentiators such as appendiceal diameter, periappendiceal air, effusion, and intraluminal appendicolith are crucial for accurate diagnosis. The findings highlight the importance of these parameters in distinguishing various types of appendicitis, offering valuable insights for clinical practice. Future prospective studies and advanced imaging techniques are needed to validate these findings and enhance the diagnosis and management of acute appendicitis and its complications.</p>","PeriodicalId":94263,"journal":{"name":"Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES","volume":"30 10","pages":"722-728"},"PeriodicalIF":0.0,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11622713/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142396524","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Dextrose neuroprolotherapy and occlusal splint treatment outcomes in occlusal trauma: Evaluation through ultrasound imaging. 咬合创伤的葡萄糖神经注射疗法和咬合夹板治疗效果:通过超声波成像进行评估。
Hilal Peker Öztürk, Aydan Örsçelik, Hatice Seda Ozgedik, Gökhan Büyüklüoğlu, Ilker Solmaz, Şahin Kaymak, Kaan Orhan

Background: Occlusal trauma has become a common phenomenon among individuals today. Its primary source is bruxism, which involves unusual activities such as clenching and grinding during the day or sleep. The hypothesis is that with 5% dextrose neuroprolotherapy, both the trigger points and affected nerves will be healed, and the muscle will be relieved by eliminating the pain.

Methods: This study aimed to compare the short-term ultrasonographic results of patients treated with occlusal splint and 5% dextrose neuroprolotherapy for bruxism. Patients were divided into two groups: the dextrose neuroprolotherapy group and the occlusal splint group. In the first group, patients were administered 5% dextrose three times at one-week intervals using the dextrose neuroprolotherapy method. Impressions for both jaws were made using a high-viscosity irreversible hydrocolloid impression material in the second group. An occlusal splint was tailored to fit the upper jaw. Patients were assessed for masseter muscle thickness and strain ratio using ultrasonography before and 3 months after the treatment.

Results: No statistically significant differences were found between the two groups for all measures. Statistically significant differences were observed in the strain ratio of the left musculus massetericus in the resting position and the thickness of the left musculus massetericus in the contracted position exclusively in the neuroprolotherapy group (p=0.001, p=0.011, respectively). Differences in the strain ratio of both sides of the contracted musculus massetericus were demonstrated in both groups (neuroprolotherapy group: right side p<0.001, left side p=0.007, splint group: right side p=0.005, left side p=0.012).

Conclusion: This study demonstrates that 5% dextrose neuroprolotherapy is an effective treatment comparable to an occlusal splint. Objectively visualizing changes in the masseter muscle through ultrasound provides clear results in the context of occlusal trauma and bruxism.

背景介绍咬合创伤已成为当今社会的一种常见现象。其主要来源是磨牙症,包括白天或睡眠时的咬牙和磨牙等异常活动。假设使用 5%葡萄糖神经注射疗法,触发点和受影响的神经都将得到治愈,肌肉也将通过消除疼痛而得到缓解:本研究旨在比较使用咬合夹板和 5%葡萄糖神经刺激疗法治疗磨牙症患者的短期超声波检查结果。患者被分为两组:葡萄糖神经刺激疗法组和咬合夹板组。在第一组中,患者使用葡萄糖神经电疗法,每隔一周注射三次 5%葡萄糖。第二组患者使用高粘度不可逆水胶体印模材料制作双颌印模。为上颌骨量身定制咬合夹板。在治疗前和治疗后 3 个月,使用超声波对患者的颌下肌厚度和应变比率进行评估:两组患者在所有指标上均无显着差异。在静息位左侧颌面肌的应变比和收缩位左侧颌面肌的厚度方面,神经电疗组的差异具有统计学意义(分别为 p=0.001 和 p=0.011)。两组患者收缩状态下两侧颌面肌的应变比率均存在差异(神经电刺激治疗组:右侧应变比率为 0.001,而神经电刺激治疗组为 0.011):本研究表明,5%葡萄糖神经刺激疗法是一种有效的治疗方法,其效果可与咬合夹板相媲美。在咬合创伤和磨牙症的情况下,通过超声波客观观察颌间肌的变化可获得清晰的结果。
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引用次数: 0
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Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES
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