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Comparison of spinopelvic fixation and iliosacral screw fixation for posterior pelvic ring injuries. 后骨盆环损伤椎盂内固定与髂骶螺钉内固定的比较。
Ekin Barış Demir, Fatih Barça, Çağrı Havıtçıoğlu, Halis Atıl Atilla, Mutlu Akdoğan

Background: There is no consensus in the literature regarding the optimal treatment method for posterior pelvic ring injuries. This study aims to compare the radiologic and clinical outcomes, as well as complications of spinopelvic fixation (SPF) and iliosacral screw fixation (ISF) in patients with posterior pelvic ring injuries.

Methods: This retrospective study analyzed 54 patients (37 females, 17 males; mean age 38.9±18.7 years) with pelvic ring injuries classified as Tile type B and type C involving the posterior pelvic ring. These patients were treated with either SPF or ISF and followed for at least one year at two centers between 2016 and 2023. Of these, 28 patients comprised the SPF group, and 26 patients were in the ISF group. Comparisons were made regarding perioperative data (hemoglobin loss, blood product replacement, hospitalization duration, intensive care unit stay, surgery time, and fluoroscopy duration) and clinical outcomes (limb length discrepancy, Majeed score, visual analogue scale (VAS) score, and Short Form-36 (SF-36) score). Radiological outcomes were assessed using Matta outcome grading. Complications were also investigated.

Results: Hemoglobin loss (median 2.2 vs. 1 g/dL; p=0.027) and surgery time (67±10.6 vs. 37.7±11.3 minutes; p<0.001) were higher in the SPF group, whereas fluoroscopy duration (median 2 vs. 51.5 seconds; p<0.001) was higher in the ISF group. Other perioperative parameters did not differ between the groups. At a minimum follow-up of one year, clinical scores (Majeed score, VAS, SF-36), limb length discrepancy, and Matta outcome grades were similar between the groups. The SPF group had higher total complication rates (46.4% vs. 19.2%; p=0.034) and infection rates (42.9% vs. 3.8%; p<0.001), while rates of neurological deficits, screw malposition, and other hospitalization complications (e.g., thromboembolic or cardiovascular events, pulmonary complications, sepsis) were not significantly different.

Conclusion: Both spinopelvic fixation and iliosacral screw fixation techniques are similarly effective in terms of clinical and radiological outcomes, with both methods demonstrating a low rate of complications. However, SPF was associated with higher infection rates and greater hemoglobin loss, while ISF required increased fluoroscopy exposure.

背景:关于骨盆后环损伤的最佳治疗方法,文献尚未达成共识。本研究旨在比较脊柱骨盆固定(SPF)和髂骶螺钉固定(ISF)治疗骨盆后环损伤患者的影像学和临床结果以及并发症。方法:对54例患者进行回顾性分析,其中女性37例,男性17例;平均年龄38.9±18.7岁),骨盆环损伤分Tile B型和C型,累及骨盆后环。这些患者接受SPF或ISF治疗,并在2016年至2023年期间在两个中心随访至少一年。其中SPF组28例,ISF组26例。比较围手术期数据(血红蛋白损失、血液制品更换、住院时间、重症监护病房时间、手术时间和透视时间)和临床结果(肢体长度差异、Majeed评分、视觉模拟评分(VAS)评分和SF-36评分)。使用Matta结果分级评估放射预后。并发症也进行了调查。结果:血红蛋白损失(中位数2.2 vs. 1 g/dL;P =0.027),手术时间(67±10.6∶37.7±11.3 min);结论:就临床和影像学结果而言,脊柱骨盆固定和髂骶螺钉固定技术同样有效,两种方法的并发症发生率均较低。然而,SPF与较高的感染率和较大的血红蛋白损失相关,而ISF需要增加透视暴露。
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引用次数: 0
Predicting mortality in adults hospitalized with multiple trauma: Can the BIG score estimate risk? 预测多重创伤住院成人的死亡率:BIG评分能评估风险吗?
Adem Az, Özgür Söğüt, Mehmet Özçömlekçi, Yunus Doğan, Tarık Akdemir

Background: This study aimed to compare the predictive performance of the BIG score (base deficit + [2.5 × international normalized ratio (INR)] + [15 - Glasgow Coma Scale (GCS)]) for in-hospital mortality in adult patients with multiple trauma against other scoring systems, including the Glasgow Coma Scale (GCS), Revised Trauma Score (RTS), and Injury Severity Score (ISS).

Methods: A retrospective single-center study was conducted, including 563 adults (aged ≥18 years) with multiple trauma who were admitted to the emergency department and hospitalized between January 2022 and December 2023. Demographic and clinical characteristics, as well as trauma scoring systems (e.g., GCS, RTS, ISS, and BIG score), were analyzed between survivors and nonsurvivors to identify factors associated with in-hospital mortality.

Results: The BIG score, along with the RTS and ISS, was identified as an independent predictor of mortality in adults with multiple trauma (p<0.001 for all comparisons). A BIG score of 10.65 was determined as the mortality cut-off, with 67.7% sensitivity and 86.5% specificity (area under the curve: 0.847; 95% confidence interval: 0.808-0.886). The BIG score demonstrated higher positive predictive value (60.8%) and negative predictive value (89.6%) compared to the other trauma scoring systems. Estimated mortality risks for BIG scores of 15 and 20 were 50% and 80%, respectively.

Conclusion: The BIG score can accurately predict in-hospital mortality in adults with multiple trauma. Additionally, the BIG score was superior to the GCS, RTS, and ISS in predicting in-hospital mortality (ClinicalTrials.gov identifier: NCT06574464).

背景:本研究旨在比较BIG评分(基本缺陷+ [2.5 ×国际标准化比率(INR)] +[15 -格拉斯哥昏迷量表(GCS)])对多重创伤成人患者住院死亡率的预测性能,与其他评分系统,包括格拉斯哥昏迷量表(GCS)、修订创伤评分(RTS)和损伤严重程度评分(ISS)。方法:采用回顾性单中心研究,纳入2022年1月至2023年12月期间急诊科收治的563例多发创伤成人(年龄≥18岁)。对幸存者和非幸存者的人口学和临床特征以及创伤评分系统(如GCS、RTS、ISS和BIG评分)进行分析,以确定与住院死亡率相关的因素。结果:BIG评分与RTS和ISS一起被确定为多重创伤成人死亡率的独立预测因子(结论:BIG评分可以准确预测多重创伤成人住院死亡率)。此外,BIG评分在预测院内死亡率方面优于GCS、RTS和ISS (ClinicalTrials.gov识别码:NCT06574464)。
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引用次数: 0
The effect of carvacrol on reducing bacterial translocation, liver and intestinal damage in obstructive jaundice models of rats. 香芹酚对梗阻性黄疸模型大鼠细菌易位及肝、肠损伤的影响。
Muhammet Fatih Keyif, Ferdi Bolat, Mustafa Sit, Songul Peltek Ozer, Mustafa Behcet, Oguz Catal, Bahri Ozer, Mehmet Hayri Erkol

BACKGROUND Obstructive jaundice is a common surgical issue caused by obstruction in the bile ducts, which can result from factors such as stones or cancers in the main bile duct. This study aimed to investigate the effects of carvacrol, a compound known for its strong antioxidant properties, on intestinal damage, liver damage, and bacterial translocation in an animal model of obstructive jaundice. METHODS The study utilized six groups of six Wistar Albino rats each. Obstructive jaundice was induced in the rats through a surgical procedure, resulting in the enlargement of the common bile duct. Carvacrol was administered at a dose of 100 mg/kg to evaluate its therapeutic effects. Blood samples were collected for biochemical analysis, and tissue samples were obtained from the ileum and liver for histopathological examination. Additionally, samples from the spleen and mesenteric lymph nodes were collected for microbiological analysis. RESULTS The findings revealed that carvacrol did not have a significant therapeutic effect on liver and bowel damage or on bacterial translocation in the rats with obstructive jaundice. Despite carvacrol's known antioxidant properties, it failed to show benefits in this experimental model. CONCLUSION Carvacrol, while recognized for its antioxidant effects, did not demonstrate therapeutic efficacy in treating obstructive jaundice in rats. The study suggests that further research with a larger sample size may be necessary to potentially uncover positive effects and better understand carvacrol's potential role in managing obstructive jaundice.

梗阻性黄疸是胆管梗阻引起的常见手术问题,可由主要胆管结石或肿瘤等因素引起。本研究旨在研究香芹酚(一种以其强抗氧化特性而闻名的化合物)对梗阻性黄疸动物模型中肠道损伤、肝损伤和细菌易位的影响。方法采用Wistar白化大鼠6组,每组6只。通过手术诱导大鼠梗阻性黄疸,导致胆总管扩大。Carvacrol以100 mg/kg的剂量给药,以评价其治疗效果。采集血样进行生化分析,回肠和肝脏组织标本进行组织病理学检查。此外,收集脾脏和肠系膜淋巴结样本进行微生物学分析。结果香芹酚对梗阻性黄疸大鼠肝、肠损伤及细菌易位无明显治疗作用。尽管香芹酚具有众所周知的抗氧化特性,但它在这个实验模型中并没有显示出益处。结论香芹酚虽然具有抗氧化作用,但对大鼠梗阻性黄疸没有明显的治疗作用。这项研究表明,进一步的研究可能需要更大的样本量来揭示其潜在的积极作用,并更好地了解香芹酚在治疗阻塞性黄疸方面的潜在作用。
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引用次数: 0
Clinical and radiographic evaluation of two different apexification protocols in traumatized immature permanent incisors. 创伤性未成熟恒切牙两种不同根尖拔除方案的临床及影像学评价。
Gülhan Koyuncuoglu, Gamze Aren

Background: Dental trauma can cause damage to the pulp tissue in immature teeth. Revascularization therapy is a possible option in the treatment of non-vital, immature permanent teeth with a history of trauma. The aim of this prospective study was to evaluate the radiographic and clinical results of immature teeth with a history of trauma treated by regenerative endodontic procedures and mineral trioxide aggregate apexification techniques.

Methods: Forty-one patients aged between 7 and 12 years with traumatized immature permanent maxillary incisors were included in the study. These patients were divided into two groups: those who had previously received endodontic treatment and those who had not. Twenty-four patients who applied directly to the university clinic and had not received endodontic treatment before were included in the regenerative endodontic protocol group (Group 1). Seventeen patients who had previously undergone endodontic intervention on their relevant teeth were included in the mineral trioxide aggregate apexification group (Group 2). The patients were followed for a period of 24 months. Clinical success rates were evaluated, and pre-treatment and control radiographs were analyzed to calculate the percentage increase in root dentin width and root length.

Results: After 24 months of follow-up, positive periapical healing was detected in the radiographic findings in the majority of cases. In Group 1, a limited increase in root length and root dentin width was observed, while a narrowing in the apical opening was evident. The radiographic evaluation of two of the cases, which could be accessed 11 years later, emphasized the importance of long-term follow-up in assessing the effectiveness of the chosen methods.

Conclusion: The revascularization method is a treatment option that has positive results in terms of root development in teeth with necrotic pulp as a result of trauma.

背景:牙外伤会对未成熟牙齿的牙髓组织造成损伤。血管重建术是治疗有外伤史的非重要的、未成熟的恒牙的一种可能的选择。本前瞻性研究的目的是评估有创伤史的未成熟牙齿采用再生牙髓治疗和三氧化二矿骨料尖化技术治疗的影像学和临床结果。方法:选取41例7 ~ 12岁的未成熟恒切外伤患者作为研究对象。这些患者被分为两组:一组以前接受过牙髓治疗,另一组没有。将24例直接向大学门诊申请且未接受过牙髓治疗的患者纳入再生牙髓治疗方案组(1组)。将17例既往接受过牙髓治疗的患者纳入三氧化二矿骨料尖化组(2组)。随访24个月。评估临床成功率,分析治疗前和对照x线片,计算根本质宽度和根长度增加的百分比。结果:随访24个月后,绝大多数病例根尖周愈合阳性。组1牙根长度和牙本质宽度增加有限,根尖开口明显变窄。其中两例的放射学评估可以在11年后获得,强调了评估所选方法有效性的长期随访的重要性。结论:血运重建术对于创伤牙髓坏死的牙根发育是一种积极的治疗方法。
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引用次数: 0
Emborrhoid technique in hemorrhoidal disease: Retrospective analysis of data from a single center. 痔疮技术在痔疮疾病中的应用:单一中心资料的回顾性分析。
Ahmet Baş, Ahmet Üstündağ, Sefa Ergün, Cesur Samancı, Süleyman Demiryas

Background: This study evaluates the safety and effectiveness of coil embolization of the superior rectal artery for both emergency and elective treatment of rectal bleeding caused by Goligher grade 4 hemorrhoids, where surgery is contraindicated.

Methods: Between 2019 and 2024, 18 patients (11 males, 7 females) with a mean age of 65±10.3 years were included in the study. Hemorrhoid grading was performed according to the Goligher classification, and rectal bleeding grading was assessed using the Paris bleeding severity score. Femoral artery access was utilized for embolization in all patients, and superior rectal artery branches were embolized exclusively with coils. All patients were treated electively except one who developed hemodynamic instability due to massive rectal bleeding while monitored in the intensive care unit. Follow-up was conducted via clinical examination and rectoscopy at 1, 3, and 6 months.

Results: All patients underwent successful treatment with 100% technical success. No procedure-related ischemic complications or femoral artery puncture-related complications were observed in any patient. All patients were classified as grade 4 according to the Goligher classification prior to treatment. The mean Paris bleeding severity score was 6.6±1.1 before treatment, 3.4±1.5 at the first month, 3.8±1.61 at the third month, and 3.6±1.29 at the sixth month. Recurrence occurred in one patient at the first month and in another at the third month. Clinical success was 95% at the first month and 85% at the third and sixth months. Re-embolization was not performed in patients with recurrence.

Conclusion: In conclusion, this study demonstrates that coil embolization of the superior rectal artery branches is a safe and effective minimally invasive procedure for both the emergency treatment of bleeding due to grade 4 hemorrhoidal disease and the elective treatment of patients unsuitable for surgical intervention.

背景:本研究评估了直肠上动脉线圈栓塞在急诊和择期治疗高氏4级痔疮引起的直肠出血的安全性和有效性,高氏4级痔疮是手术禁忌。方法:2019 - 2024年共纳入18例患者(男11例,女7例),平均年龄65±10.3岁。根据Goligher分级进行痔疮分级,使用Paris出血严重程度评分评估直肠出血分级。所有患者均使用股动脉通道进行栓塞,直肠上动脉分支仅使用线圈进行栓塞。除1例患者在重症监护病房监测期间因直肠大出血而出现血流动力学不稳定外,所有患者均接受选择性治疗。随访分别于1、3、6个月进行临床检查和直肠镜检查。结果:所有患者均成功治疗,技术成功率100%。所有患者均未出现手术相关的缺血性并发症或股动脉穿刺相关并发症。所有患者治疗前按照Goligher分级为4级。治疗前Paris出血严重程度评分平均为6.6±1.1分,第1个月为3.4±1.5分,第3个月为3.8±1.61分,第6个月为3.6±1.29分。1例患者在第1个月复发,另1例在第3个月复发。第一个月的临床成功率为95%,第三个月和第六个月的临床成功率为85%。复发患者不进行再次栓塞。结论:综上所述,直肠上动脉分支线圈栓塞术无论对于4级痔疮出血的急诊治疗,还是对于不适合手术干预的患者的选择性治疗,都是一种安全有效的微创治疗方法。
{"title":"Emborrhoid technique in hemorrhoidal disease: Retrospective analysis of data from a single center.","authors":"Ahmet Baş, Ahmet Üstündağ, Sefa Ergün, Cesur Samancı, Süleyman Demiryas","doi":"10.14744/tjtes.2024.79406","DOIUrl":"10.14744/tjtes.2024.79406","url":null,"abstract":"<p><strong>Background: </strong>This study evaluates the safety and effectiveness of coil embolization of the superior rectal artery for both emergency and elective treatment of rectal bleeding caused by Goligher grade 4 hemorrhoids, where surgery is contraindicated.</p><p><strong>Methods: </strong>Between 2019 and 2024, 18 patients (11 males, 7 females) with a mean age of 65±10.3 years were included in the study. Hemorrhoid grading was performed according to the Goligher classification, and rectal bleeding grading was assessed using the Paris bleeding severity score. Femoral artery access was utilized for embolization in all patients, and superior rectal artery branches were embolized exclusively with coils. All patients were treated electively except one who developed hemodynamic instability due to massive rectal bleeding while monitored in the intensive care unit. Follow-up was conducted via clinical examination and rectoscopy at 1, 3, and 6 months.</p><p><strong>Results: </strong>All patients underwent successful treatment with 100% technical success. No procedure-related ischemic complications or femoral artery puncture-related complications were observed in any patient. All patients were classified as grade 4 according to the Goligher classification prior to treatment. The mean Paris bleeding severity score was 6.6±1.1 before treatment, 3.4±1.5 at the first month, 3.8±1.61 at the third month, and 3.6±1.29 at the sixth month. Recurrence occurred in one patient at the first month and in another at the third month. Clinical success was 95% at the first month and 85% at the third and sixth months. Re-embolization was not performed in patients with recurrence.</p><p><strong>Conclusion: </strong>In conclusion, this study demonstrates that coil embolization of the superior rectal artery branches is a safe and effective minimally invasive procedure for both the emergency treatment of bleeding due to grade 4 hemorrhoidal disease and the elective treatment of patients unsuitable for surgical intervention.</p>","PeriodicalId":94263,"journal":{"name":"Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES","volume":"31 1","pages":"47-51"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11843397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous cholecystostomy in elderly patients with acute cholecystitis: Factors influencing mortality, morbidity, and length of hospital stay. 老年急性胆囊炎患者经皮胆囊造瘘术:影响死亡率、发病率和住院时间的因素
Emre Teke, Birol Agca, Yasin Güneş, Gamze Nur Teke, Ahmet Said Yaz, M Timucin Aydin, Ahmet Başak, Gülşah Yıldırım

Background: Acute cholecystitis (AC) is increasingly common and imposes a burden on healthcare systems, particularly in the elderly population. While laparoscopic cholecystectomy (LC) is the definitive treatment, percutaneous cholecystostomy (PC) is often preferred based on various factors. The treatment of elderly patients requires a multidisciplinary approach that carefully assesses surgical risks due to age-related changes and comorbidities. This retrospective study evaluates factors affecting mortality, morbidity, and hospital stay in elderly patients diagnosed with AC who presented to the emergency department and underwent PC.

Methods: This retrospective study, conducted between January 2013 and January 2021, included patients aged 70 years and older with grade 2 and 3 AC, as classified by the Tokyo Guidelines, who underwent PC. Data on laboratory parameters, comorbidities, and outcomes were collected and analyzed.

Results: Among the 76 included patients, complications occurred in 7.9% of cases, with catheter replacement being the most common complication. In-hospital mortality was 5.2%. Factors influencing hospital stay included intervention timing and serum albumin levels. Placement of percutaneous cholecystostomy within the first three days of hospitalization has been shown to shorten the length of hospital stay.

Conclusion: Personalized treatment strategies are essential for managing AC in elderly patients. Early placement of PC may reduce hospital stays and associated costs. Further research and updated guidelines are necessary to optimize outcomes in this demographic group.

背景:急性胆囊炎(AC)越来越普遍,并对卫生保健系统造成负担,特别是在老年人中。虽然腹腔镜胆囊切除术(LC)是最终的治疗方法,但基于各种因素,经皮胆囊造口术(PC)往往是首选。老年患者的治疗需要多学科的方法,仔细评估由于年龄相关的变化和合并症的手术风险。本回顾性研究评估了在急诊科诊断为AC并行PC的老年患者中影响死亡率、发病率和住院时间的因素。方法:这项回顾性研究于2013年1月至2021年1月进行,纳入了70岁及以上的2级和3级AC患者,根据东京指南分类,接受了PC治疗。收集和分析实验室参数、合并症和结果的数据。结果:76例患者中,并发症发生率为7.9%,以导管置换术为最常见的并发症。住院死亡率为5.2%。影响住院时间的因素包括干预时间和血清白蛋白水平。经皮胆囊造瘘术在住院头三天内放置已被证明可以缩短住院时间。结论:个性化治疗策略对老年AC患者的治疗至关重要。早期安置PC可减少住院时间和相关费用。进一步的研究和更新的指南是必要的,以优化这一人口群体的结果。
{"title":"Percutaneous cholecystostomy in elderly patients with acute cholecystitis: Factors influencing mortality, morbidity, and length of hospital stay.","authors":"Emre Teke, Birol Agca, Yasin Güneş, Gamze Nur Teke, Ahmet Said Yaz, M Timucin Aydin, Ahmet Başak, Gülşah Yıldırım","doi":"10.14744/tjtes.2024.94489","DOIUrl":"10.14744/tjtes.2024.94489","url":null,"abstract":"<p><strong>Background: </strong>Acute cholecystitis (AC) is increasingly common and imposes a burden on healthcare systems, particularly in the elderly population. While laparoscopic cholecystectomy (LC) is the definitive treatment, percutaneous cholecystostomy (PC) is often preferred based on various factors. The treatment of elderly patients requires a multidisciplinary approach that carefully assesses surgical risks due to age-related changes and comorbidities. This retrospective study evaluates factors affecting mortality, morbidity, and hospital stay in elderly patients diagnosed with AC who presented to the emergency department and underwent PC.</p><p><strong>Methods: </strong>This retrospective study, conducted between January 2013 and January 2021, included patients aged 70 years and older with grade 2 and 3 AC, as classified by the Tokyo Guidelines, who underwent PC. Data on laboratory parameters, comorbidities, and outcomes were collected and analyzed.</p><p><strong>Results: </strong>Among the 76 included patients, complications occurred in 7.9% of cases, with catheter replacement being the most common complication. In-hospital mortality was 5.2%. Factors influencing hospital stay included intervention timing and serum albumin levels. Placement of percutaneous cholecystostomy within the first three days of hospitalization has been shown to shorten the length of hospital stay.</p><p><strong>Conclusion: </strong>Personalized treatment strategies are essential for managing AC in elderly patients. Early placement of PC may reduce hospital stays and associated costs. Further research and updated guidelines are necessary to optimize outcomes in this demographic group.</p>","PeriodicalId":94263,"journal":{"name":"Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES","volume":"31 1","pages":"59-65"},"PeriodicalIF":0.0,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11843392/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142960959","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
The role of oxidative stress and antioxidants in older individuals with osteoporotic hip fractures. 氧化应激和抗氧化剂在老年骨质疏松性髋部骨折中的作用。
Mustafa Aydın, Emre Avcı

Background: Osteoporosis is characteristically defined as a decrease in bone density and mass, accompanied by the deterioration of bone structure, which increases bone fragility and the risk of fractures. Osteoporosis frequently develops with age. In high-risk populations, oxidative damage is a common pathological condition. Oxidative stress plays a critical role in the development of osteoporosis and the formation of osteoporosis-related fractures. This study aimed to investigate the role of oxidative stress and antioxidants in bone tissue metabolism among elderly individuals with osteoporotic hip fractures, specifically intertrochanteric femur fractures and femoral neck fractures, who presented to our department.

Methods: Based on power analysis, 24 patients over the age of 65 who presented with hip pain following a fall, were diagnosed with hip fractures (intertrochanteric or femoral neck fractures) on X-ray, were hospitalized in the Orthopedics and Traumatology Department, and underwent surgery were included in the study. A control group consisting of 24 healthy individuals matched for age and gender, with no history of fractures and meeting the same exclusion criteria, was also included. Levels of oxidative stress and antioxidant parameters, including total antioxidant status (TAS), total oxidant status (TOS), oxidative stress index (OSI), and paraoxonase-1 (PON-1), were measured in serum samples using spectrophotometric methods.

Results: The TAS (p=0.189) and OSI (p=0.110) levels in the patient group were significantly lower compared to the control group. Conversely, the TOS (p=0.002) and PON-1 (p=0.013) levels in the patient group were significantly higher than those in the control group.

Conclusion: The data indicate that oxidative balance is disrupted due to increased oxidative load and the resulting antioxidant deficiency. A better understanding of the pathophysiology of the disease, along with the development of alternative treatment approaches and disease markers, will contribute to the literature.

背景:骨质疏松症的特征定义为骨密度和骨量的减少,伴随着骨结构的恶化,这增加了骨的脆弱性和骨折的风险。骨质疏松症常随年龄增长而发展。在高危人群中,氧化损伤是一种常见的病理状况。氧化应激在骨质疏松症的发展和骨质疏松相关骨折的形成中起着关键作用。本研究旨在探讨氧化应激和抗氧化剂在老年骨质疏松性髋部骨折,特别是股骨粗隆间骨折和股骨颈骨折患者骨组织代谢中的作用。方法:采用幂次分析方法,选取24例65岁以上因跌倒后出现髋部疼痛,经x线检查诊断为髋部骨折(股骨粗隆间骨折或股骨颈骨折),在骨科创伤科住院并行手术治疗的患者。对照组由24名年龄和性别匹配的健康个体组成,没有骨折史,符合相同的排除标准。采用分光光度法测定血清样品的氧化应激水平和抗氧化参数,包括总抗氧化状态(TAS)、总氧化状态(TOS)、氧化应激指数(OSI)和对氧磷酶-1 (PON-1)。结果:患者组TAS (p=0.189)、OSI (p=0.110)水平明显低于对照组。相反,患者组的TOS (p=0.002)和PON-1 (p=0.013)水平显著高于对照组。结论:数据表明氧化负荷增加导致氧化平衡被破坏,从而导致抗氧化剂缺乏。更好地了解疾病的病理生理学,以及替代治疗方法和疾病标志物的发展,将有助于文献。
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引用次数: 0
The effect of degenerative scoliosis and spinopelvic parameters on dislocation of hip hemiarthroplasty. 退行性脊柱侧凸和旋转骨盆参数对髋关节半关节置换术脱位的影响。
Sevan Sıvacıoğlu, Mustafa Caglar Kır, Ali Çağrı Tekin, Mehmet Selçuk Saygılı, Mehmet Kurşad Bayraktar, Ali Kafadar, Gülay Kır, Hülya Kurtul Yıldız, Esra Akdas Tekin, Sertac Tatar

Background: Degeneration of the spine may affect pelvic parameters and hip mobility. This study aimed to evaluate the effects of degenerative scoliosis and spinopelvic parameters on hip hemiarthroplasty dislocations.

Methods: A retrospective analysis was conducted on patients who underwent hemiarthroplasty for intracapsular hip fracture over a twenty-year period. Demographic data, dislocation incidence, degenerative scoliosis (DS) status, type of hemiarthroplasty, surgical intervention to the hip, femoral head size, cement use, American Society of Anesthesiologists (ASA) score, body mass index (BMI), and in-hospital mortality were evaluated. The Cobb angle (CA), pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT), lumbar lordosis (LL), and thoracic kyphosis (TK) angles were measured and analyzed.

Results: A total of 284 patients were evaluated, with a mean age of 79.07 (±8.21) years. The frequency of hemiarthroplasty dislocation was 13% (n=37). Degenerative scoliosis was detected in 25.4% of the cases and was significantly more common in patients with degenerative scoliosis (p=0.001). Advanced age, higher BMI, higher ASA score, unipolar and cementless hemiarthroplasty, smaller femoral head size, and the posterior approach significantly increased dislocation frequency (p=0.004, p=0.001, p=0.03, p=0.001, p=0.001, and p=0.026, respectively). The mean PI, SS, PT, LL, and TK angles were significantly reduced in patients with dislocation and degenerative scoliosis (dislocation: p=0.001, p=0.001, p=0.001, p=0.003, p=0.048; degenerative scoliosis: p=0.001, p=0.001, p=0.001, p=0.001, p=0.001; respectively).

Conclusion: The presence of degenerative scoliosis and low pelvic incidence, sacral slope, pelvic tilt, thoracic kyphosis, and lumbar lordosis angles may increase the frequency of hemiarthroplasty dislocations. The posterior approach and small femoral head size may also elevate the risk of posterior dislocation.

背景:脊柱退变可能会影响骨盆参数和髋关节活动度。本研究旨在评估退行性脊柱侧弯和脊柱骨盆参数对髋关节半关节成形术后脱位的影响:对二十年间因髋关节囊内骨折接受半关节成形术的患者进行了回顾性分析。对人口统计学数据、脱位发生率、退行性脊柱侧凸(DS)状态、半关节成形术类型、髋关节手术干预、股骨头大小、骨水泥使用、美国麻醉医师协会(ASA)评分、体重指数(BMI)和院内死亡率进行了评估。测量并分析了Cobb角(CA)、骨盆入射角(PI)、骶骨斜度(SS)、骨盆倾斜度(PT)、腰椎前凸(LL)和胸椎后凸角(TK):共评估了 284 名患者,平均年龄为 79.07 (±8.21) 岁。半关节成形术脱位发生率为13%(n=37)。25.4%的病例发现了退行性脊柱侧凸,且退行性脊柱侧凸患者的发病率明显更高(P=0.001)。高龄、较高的体重指数(BMI)、较高的ASA评分、单极性和无骨水泥半关节成形术、较小的股骨头尺寸以及后入路都会显著增加脱位频率(分别为P=0.004、P=0.001、P=0.03、P=0.001、P=0.001和P=0.026)。脱位和退行性脊柱侧凸患者的平均PI、SS、PT、LL和TK角度显著减小(脱位:分别为P=0.001、P=0.001、P=0.001、P=0.003、P=0.048;退行性脊柱侧凸:分别为P=0.001、P=0.001、P=0.001、P=0.001、P=0.001):结论:退行性脊柱侧凸和骨盆入径低、骶骨斜度低、骨盆倾斜、胸椎后凸和腰椎前凸角度低可能会增加半关节成形术脱位的频率。后入路和小股骨头也可能会增加后脱位的风险。
{"title":"The effect of degenerative scoliosis and spinopelvic parameters on dislocation of hip hemiarthroplasty.","authors":"Sevan Sıvacıoğlu, Mustafa Caglar Kır, Ali Çağrı Tekin, Mehmet Selçuk Saygılı, Mehmet Kurşad Bayraktar, Ali Kafadar, Gülay Kır, Hülya Kurtul Yıldız, Esra Akdas Tekin, Sertac Tatar","doi":"10.14744/tjtes.2024.83696","DOIUrl":"10.14744/tjtes.2024.83696","url":null,"abstract":"<p><strong>Background: </strong>Degeneration of the spine may affect pelvic parameters and hip mobility. This study aimed to evaluate the effects of degenerative scoliosis and spinopelvic parameters on hip hemiarthroplasty dislocations.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on patients who underwent hemiarthroplasty for intracapsular hip fracture over a twenty-year period. Demographic data, dislocation incidence, degenerative scoliosis (DS) status, type of hemiarthroplasty, surgical intervention to the hip, femoral head size, cement use, American Society of Anesthesiologists (ASA) score, body mass index (BMI), and in-hospital mortality were evaluated. The Cobb angle (CA), pelvic incidence (PI), sacral slope (SS), pelvic tilt (PT), lumbar lordosis (LL), and thoracic kyphosis (TK) angles were measured and analyzed.</p><p><strong>Results: </strong>A total of 284 patients were evaluated, with a mean age of 79.07 (±8.21) years. The frequency of hemiarthroplasty dislocation was 13% (n=37). Degenerative scoliosis was detected in 25.4% of the cases and was significantly more common in patients with degenerative scoliosis (p=0.001). Advanced age, higher BMI, higher ASA score, unipolar and cementless hemiarthroplasty, smaller femoral head size, and the posterior approach significantly increased dislocation frequency (p=0.004, p=0.001, p=0.03, p=0.001, p=0.001, and p=0.026, respectively). The mean PI, SS, PT, LL, and TK angles were significantly reduced in patients with dislocation and degenerative scoliosis (dislocation: p=0.001, p=0.001, p=0.001, p=0.003, p=0.048; degenerative scoliosis: p=0.001, p=0.001, p=0.001, p=0.001, p=0.001; respectively).</p><p><strong>Conclusion: </strong>The presence of degenerative scoliosis and low pelvic incidence, sacral slope, pelvic tilt, thoracic kyphosis, and lumbar lordosis angles may increase the frequency of hemiarthroplasty dislocations. The posterior approach and small femoral head size may also elevate the risk of posterior dislocation.</p>","PeriodicalId":94263,"journal":{"name":"Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES","volume":"30 11","pages":"813-820"},"PeriodicalIF":0.0,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11843382/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142585356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Comparison of three different methods for stump closure in laparoscopic appendectomy: Endoloop, Hem-o-lok clip, and endostapler. 比较腹腔镜阑尾切除术中三种不同的残端闭合方法:Endoloop、Hem-o-lok 夹和 endostapler。
Sefa Ergun, Pırıltı Ozcan, Fatma Ipek Gunaydin, Egemen Ozdemir, Selen Soylu Yalıman, Yasemin Pekmezci, Engin Hatipoglu, Ahmet Bas, Osman Simsek, Salih Pekmezci

Background: Acute appendicitis is a common surgical emergency that causes acute abdominal pain and affects approximately 7-8% of the population during their lifetime. The closure of the appendix stump during laparoscopic appendectomy is one of the most critical steps of the surgery to prevent life-threatening complications such as postoperative fistula, peritonitis, and sepsis. The mate-rial chosen for appendix stump closure must be effective, safe, and economical. However, there is still no consensus on the optimal method for stump closure. In this study, we aimed to compare the advantages and reliability of three different methods used for appendix stump closure.

Methods: At Istanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty, Department of General Surgery, cases that underwent laparoscopic appendectomy for acute appendicitis between January 2022 and April 2024 were retrospectively analyzed using the hospital's data system. The patients' demographic data, laboratory values, pathology reports, surgical notes, duration of hospital stay, duration of surgery, total hospital costs, complications related to the surgery within 30 days postoperatively, and the management of these complications were examined.

Results: The study included a total of 150 individuals, with 83 (55.33%) males and 67 (44.67%) females. The average age of the participants was 38.45±14.48 years. In terms of the materials used for stump closure, endoloop was used in 82 (54.67%) cases, Hem-o-lok clip in 30 (20.00%) cases, and endostapler in 38 (25.33%) cases. In 144 (96%) cases, no Clavien-Dindo (CD) complications were observed, while complications occurred in six (4%) cases. These six complications included two intra-abdominal abscesses (CD Grade 3), two wound infections (CD Grade 1), one case of bleeding (CD Grade 2), and one pulmonary embolism (CD Grade 4).

Conclusion: The use of endoloop, polymeric clips, and endostapler in laparoscopic appendectomy is safe and effective for appendectomy. All three methods can be successfully applied without an increase in intraoperative or postoperative complications. However, due to the higher treatment costs associated with endostapler, its use should be reserved for situations where securing the appendix stump cannot be achieved with endoloop or Hem-o-lok clip.

背景:急性阑尾炎是一种常见的外科急腹症,会引起急性腹痛,一生中约有 7%-8% 的人受到影响。腹腔镜阑尾切除术中阑尾残端闭合是手术中最关键的步骤之一,可防止术后瘘管、腹膜炎和败血症等危及生命的并发症。用于阑尾残端闭合的配型必须有效、安全和经济。然而,关于阑尾残端闭合的最佳方法仍未达成共识。在这项研究中,我们旨在比较用于阑尾残端闭合的三种不同方法的优势和可靠性:伊斯坦布尔大学切拉帕萨分校(Istanbul University-Cerrahpaşa, Cerrahpaşa Medical Faculty)普外科利用医院的数据系统对 2022 年 1 月至 2024 年 4 月间因急性阑尾炎接受腹腔镜阑尾切除术的病例进行了回顾性分析。对患者的人口统计学数据、化验值、病理报告、手术记录、住院时间、手术时间、住院总费用、术后 30 天内与手术相关的并发症以及对这些并发症的处理进行了研究:研究共涉及 150 人,其中男性 83 人(55.33%),女性 67 人(44.67%)。参与者的平均年龄为(38.45±14.48)岁。就用于残端闭合的材料而言,82 例(54.67%)使用了 endoloop,30 例(20.00%)使用了 Hem-o-lok 夹,38 例(25.33%)使用了 endostapler。在 144 例(96%)病例中未观察到克拉维恩-丁多(CD)并发症,而在 6 例(4%)病例中出现了并发症。这 6 例并发症包括 2 例腹腔内脓肿(CD 3 级)、2 例伤口感染(CD 1 级)、1 例出血(CD 2 级)和 1 例肺栓塞(CD 4 级):结论:在腹腔镜阑尾切除术中使用endoloop、聚合夹和endostapler是安全有效的。这三种方法都能成功应用,且不会增加术中或术后并发症。不过,由于内固定器的治疗成本较高,因此应仅限于无法使用内固定器或Hem-o-lok夹固定阑尾残端的情况。
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引用次数: 0
Shoulder disarticulation after clavicle fracture: a case report. 锁骨骨折后肩关节脱位:病例报告。
Bilge Kağan Yılmaz, Mohamed Salah Alı, İbrahim Ethem Bütüner, Gökhan Maralcan

In this case report, we presented to a 90-year-old female with multiple comorbidities presented to the emergency department of our hospital three weeks following a fall from standing height. Upon arrival, the patient exhibited a Glasgow Coma Scale (GCS) 12, blood pressure of 100/60 mmHg, heart rate of 117 beats/min, respiratory rate of 24 breaths/min. Examination revealed atrophy, skin color change, sensory disturbance, or motor palsy in the left upper extremity. Chest X-ray showed a fractured left clavicle, with its free fragment dislocated toward the thorax. She was diagnosed with a displaced midshaft clavicle fracture, Arbeitsgemeinschaft für Osteosynthesefragen (AO) type 15.2B2. On doppler ultrasound examination, flow loss secondary to compression was observed in the proximal left subclavian artery (SA). No flow was observed in the axillary, brachial, radial and ulnar arteries. Due to the patient's high number of comorbid diseases and poor general condition, disarticulation was performed from the shoulder joint, which is the proximal region of arterial occlusion. No other symptoms of circulatory dysfunction were observed at the 3 months follow-up. This case report emphasizes that delayed clavicle fracture can lead to catastrophic consequences. Trauma surgeons should also consider surgical treatment of clavicle fractures, depending on the patient's condition.

在本病例报告中,我们介绍了一名患有多种并发症的 90 岁女性患者在从站立高度摔下三周后到我院急诊科就诊的情况。到达医院时,患者的格拉斯哥昏迷量表(GCS)为 12,血压为 100/60 mmHg,心率为 117 次/分,呼吸频率为 24 次/分。检查发现患者左上肢萎缩、皮肤颜色改变、感觉障碍或运动麻痹。胸部 X 光片显示左锁骨骨折,其游离碎片向胸腔脱位。她被诊断为锁骨中轴移位性骨折,属于Arbeitsgemeinschaft für Osteosynthesefragen(AO)15.2B2型。多普勒超声检查发现,左锁骨下动脉(SA)近端因受压而血流减少。腋动脉、肱动脉、桡动脉和尺动脉均未观察到血流。由于患者合并症较多,且全身状况不佳,因此从肩关节(即动脉闭塞的近端区域)进行了分离。3 个月的随访未发现其他循环功能障碍症状。本病例报告强调,延迟性锁骨骨折可导致灾难性后果。创伤外科医生也应根据患者的情况考虑对锁骨骨折进行手术治疗。
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