Sul Hee Lee, Kee Yang Chung, Sooyie Choi, Thanya Techapichetvanich
{"title":"Rare Cutaneous Soft Tissue Sarcomas Treated With Slow Mohs Micrographic Surgery: Ten Years' Experience at a Single Institution.","authors":"Sul Hee Lee, Kee Yang Chung, Sooyie Choi, Thanya Techapichetvanich","doi":"10.5021/ad.21.101","DOIUrl":"https://doi.org/10.5021/ad.21.101","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10995616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140867914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Joo Yeon Ko, Chang Hwa Song, Kwang Joong Kim, Nack In Kim, Jung Eun Kim, Hei Sung Kim, Young Suck Ro, Kui Young Park, Mi-Youn Park, Dae Hun Suh, Kihyuck Shin, Min Kyung Shin, Hyo Hyun Ahn, Woo Jin Lee, Weon Ju Lee, Ju Hee Lee, Jee Bum Lee, Hae Woong Lee, Hee Jung Lee, Min Soo Jang, Seung Hyun Cheong, Soyun Cho, Yu Sung Choi, You Won Choi, Hoon Choi, Mi Woo Lee
Background: More than half of acne patients have truncal acne on their chest, back, and shoulders. However, since most studies on acne have focused on the face, data on clinical characteristics and proper management for truncal acne are insufficient.
Objective: To establish a Korean Acne Rosacea Society (KARS) consensus for experts' perception and treatment patterns of truncal acne.
Methods: We conducted two rounds of the Dephi technique to gather expert opinion and reach a consensus on truncal acne. The first round comprised 48 questionnaires focusing on various aspects such as epidemiology, clinical features, diagnosis, treatment, prognosis and more, while second rounds consisted of 26 questionnaires.
Results: A total of 36 dermatologists (36/38 KARS members, 94.7%) completed this survey. In the first-round survey, consensus was reached on 20 out of the 48 questions (41.7%). In the second-round questionnaire, consensus was achieved on 9 of the 26 questions (34.6%). The most unresponsive lesion to truncal acne treatment was scars (atrophic/hypertrophic). The most commonly used treatments for each non-inflammatory and inflammatory truncal acne lesions were selected to use topical retinoids (78.1% of the responders) and oral antibiotics (93.8% of the responders).
Conclusion: Our study has yielded valuable insights into the epidemiology, clinical manifestations, diagnosis, treatment, and quality of life of patients with truncal acne. We anticipate that this study will inspire further comprehensive research for individuals with truncal acne.
{"title":"Consensus Report on Truncal Acne: The Korean Acne and Rosacea Society Experts Panel.","authors":"Joo Yeon Ko, Chang Hwa Song, Kwang Joong Kim, Nack In Kim, Jung Eun Kim, Hei Sung Kim, Young Suck Ro, Kui Young Park, Mi-Youn Park, Dae Hun Suh, Kihyuck Shin, Min Kyung Shin, Hyo Hyun Ahn, Woo Jin Lee, Weon Ju Lee, Ju Hee Lee, Jee Bum Lee, Hae Woong Lee, Hee Jung Lee, Min Soo Jang, Seung Hyun Cheong, Soyun Cho, Yu Sung Choi, You Won Choi, Hoon Choi, Mi Woo Lee","doi":"10.5021/ad.23.057","DOIUrl":"10.5021/ad.23.057","url":null,"abstract":"<p><strong>Background: </strong>More than half of acne patients have truncal acne on their chest, back, and shoulders. However, since most studies on acne have focused on the face, data on clinical characteristics and proper management for truncal acne are insufficient.</p><p><strong>Objective: </strong>To establish a Korean Acne Rosacea Society (KARS) consensus for experts' perception and treatment patterns of truncal acne.</p><p><strong>Methods: </strong>We conducted two rounds of the Dephi technique to gather expert opinion and reach a consensus on truncal acne. The first round comprised 48 questionnaires focusing on various aspects such as epidemiology, clinical features, diagnosis, treatment, prognosis and more, while second rounds consisted of 26 questionnaires.</p><p><strong>Results: </strong>A total of 36 dermatologists (36/38 KARS members, 94.7%) completed this survey. In the first-round survey, consensus was reached on 20 out of the 48 questions (41.7%). In the second-round questionnaire, consensus was achieved on 9 of the 26 questions (34.6%). The most unresponsive lesion to truncal acne treatment was scars (atrophic/hypertrophic). The most commonly used treatments for each non-inflammatory and inflammatory truncal acne lesions were selected to use topical retinoids (78.1% of the responders) and oral antibiotics (93.8% of the responders).</p><p><strong>Conclusion: </strong>Our study has yielded valuable insights into the epidemiology, clinical manifestations, diagnosis, treatment, and quality of life of patients with truncal acne. We anticipate that this study will inspire further comprehensive research for individuals with truncal acne.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861305/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
So Hee Park, Sang Woo Ahn, Seung Hee Jang, Seong Min Hong, Woo Jung Jin, Jung Eun Seol, So Young Jung, Hyojin Kim
{"title":"A Comparative Study on Clinico-Histopathological Features of Granulomatous Rosacea and Lupus Miliaris Disseminatus Faciei.","authors":"So Hee Park, Sang Woo Ahn, Seung Hee Jang, Seong Min Hong, Woo Jung Jin, Jung Eun Seol, So Young Jung, Hyojin Kim","doi":"10.5021/ad.22.229","DOIUrl":"10.5021/ad.22.229","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861309/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704380","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mitchell M Pitlick, Stephen Johnson, Roshini M Mullakary, Veena Taneja, Avni Y Joshi
{"title":"Multi-Site Microbiome Composition in Atopic Dermatitis: A Case-Control Study.","authors":"Mitchell M Pitlick, Stephen Johnson, Roshini M Mullakary, Veena Taneja, Avni Y Joshi","doi":"10.5021/ad.22.117","DOIUrl":"10.5021/ad.22.117","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861306/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"A Case of Multiple Apocrine Hidrocystomas Accompanied by Inflammation on Bilateral Axillae.","authors":"Sangmin Choi, Bark-Lynn Lew, Soon-Hyo Kwon","doi":"10.5021/ad.21.145","DOIUrl":"10.5021/ad.21.145","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Youngbeom Kim, Jungsoo Lee, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Kihyuk Shin
Hidradenitis suppurativa (HS) is an inflammatory disorder characterized by chronic deep-seated nodules, abscesses, fistulae, sinus tracts, and scars in apocrine gland-bearing regions. Assessing its severity is challenging because of its clinical heterogeneity, lack of a standardized tool, and increasing severity scores. This article provides a chronological overview of HS grading scales to aid in the understanding and comparison of different scoring systems. A literature review of articles published in English on PubMed was conducted searched from 1989 to 2023. The review includes 15 scores that are the most relevant and widely used and acknowledges the existence of over 30 scoring systems for HS. The expanding landscape of HS scoring systems presents challenges when patients evaluated using different systems are compared. A universally accepted scoring system is required for consistent application across diverse populations. A comprehensive assessment should balance subjective and objective items, considering observer-reported signs and patient-reported symptoms to make meaningful treatment decisions.
{"title":"Review of Scoring Systems for Hidradenitis Suppurativa.","authors":"Youngbeom Kim, Jungsoo Lee, Hoon-Soo Kim, Hyun-Chang Ko, Byung-Soo Kim, Moon-Bum Kim, Kihyuk Shin","doi":"10.5021/ad.23.090","DOIUrl":"10.5021/ad.23.090","url":null,"abstract":"<p><p>Hidradenitis suppurativa (HS) is an inflammatory disorder characterized by chronic deep-seated nodules, abscesses, fistulae, sinus tracts, and scars in apocrine gland-bearing regions. Assessing its severity is challenging because of its clinical heterogeneity, lack of a standardized tool, and increasing severity scores. This article provides a chronological overview of HS grading scales to aid in the understanding and comparison of different scoring systems. A literature review of articles published in English on PubMed was conducted searched from 1989 to 2023. The review includes 15 scores that are the most relevant and widely used and acknowledges the existence of over 30 scoring systems for HS. The expanding landscape of HS scoring systems presents challenges when patients evaluated using different systems are compared. A universally accepted scoring system is required for consistent application across diverse populations. A comprehensive assessment should balance subjective and objective items, considering observer-reported signs and patient-reported symptoms to make meaningful treatment decisions.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861310/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704385","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hyun Jeong Ju, Soo Hyung Kim, Seo Gyeong Lee, Jung Min Bae
{"title":"Eyelash Dyeing for Poliosis of Eyelashes in Patients With Vitiligo.","authors":"Hyun Jeong Ju, Soo Hyung Kim, Seo Gyeong Lee, Jung Min Bae","doi":"10.5021/ad.22.171","DOIUrl":"10.5021/ad.22.171","url":null,"abstract":"","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704382","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jung Min Lee, Su-Jin Park, Yu-Jin Kim, Su-Young Kim, Yoo-Na Jang, A Yeon Park, Seong-Hyun Ho, Dayoung Kim, Jung Ok Lee, Kwang-Ho Yoo, Beom Joon Kim
Background: Actinidia polygama (silver vine) has been used in oriental medicine to treat gout, rheumatoid arthritis, and inflammation. Actinidia polygama water extract (APWE) is named PB203.
Objective: To investigate whether PB203 has anti-photoaging effects and to understand the molecular mechanism underlying such effects.
Methods: The antioxidant effect was assessed by 1,1-diphenyl-2-picrylhydrazyl assay and 2',7'-dichlorodihydrofluorescein diacetate staining in ultraviolet B (UVB)-irradiated HaCaT cells with or without PB203 treatment. Type I collagen, matrix metalloproteinase-1 (MMP-1), tissue inhibitor of metalloproteinase (TIMP-1), hyaluronic acid (HA), hyaluronan synthase 1 (HAS1) and HAS2 levels were measuring by enzyme-linked immunosorbent assay or reverse transcription quantitative polymerase chain reaction. Also, we investigate the effects of PB203 on wrinkle formation, and the potential mechanisms underlying such effects were investigated in UVB-induced wrinkle mouse model mice.
Results: PB203 alleviated the UVB-induced reactive oxygen species production, phosphorylation of JNK, ERK, and p38, and formation of AP-1. In addition, PB203 inhibited the decreases in type I collagen and TIMP-1 levels, and the increase in MMP-1 levels in UVB-exposed HaCaT cells. In UVB-induced wrinkle mouse model, PB203 inhibited the decreases in elastin and type I collagen levels as well as the increases in MMP-1 expression, wrinkle formation, and skin dehydration. Furthermore, PB203 increased the expression of filaggrin, HAS1, and HAS2, improving the skin barrier function.
Conclusion: Taken together, we found that PB203 is as a potent candidate to serve as a functional ingredient or therapeutic agent to improve UVB-mediated skin aging.
{"title":"<i>Actinidia polygama</i> Water Extract (APWE) Protects Against UVB-Induced Photoaging via MAPK/AP-1 and TGFβ-Smad Pathway.","authors":"Jung Min Lee, Su-Jin Park, Yu-Jin Kim, Su-Young Kim, Yoo-Na Jang, A Yeon Park, Seong-Hyun Ho, Dayoung Kim, Jung Ok Lee, Kwang-Ho Yoo, Beom Joon Kim","doi":"10.5021/ad.23.010","DOIUrl":"10.5021/ad.23.010","url":null,"abstract":"<p><strong>Background: </strong><i>Actinidia polygama</i> (silver vine) has been used in oriental medicine to treat gout, rheumatoid arthritis, and inflammation. <i>Actinidia polygama</i> water extract (APWE) is named PB203.</p><p><strong>Objective: </strong>To investigate whether PB203 has anti-photoaging effects and to understand the molecular mechanism underlying such effects.</p><p><strong>Methods: </strong>The antioxidant effect was assessed by 1,1-diphenyl-2-picrylhydrazyl assay and 2',7'-dichlorodihydrofluorescein diacetate staining in ultraviolet B (UVB)-irradiated HaCaT cells with or without PB203 treatment. Type I collagen, matrix metalloproteinase-1 (MMP-1), tissue inhibitor of metalloproteinase (TIMP-1), hyaluronic acid (HA), hyaluronan synthase 1 (HAS1) and HAS2 levels were measuring by enzyme-linked immunosorbent assay or reverse transcription quantitative polymerase chain reaction. Also, we investigate the effects of PB203 on wrinkle formation, and the potential mechanisms underlying such effects were investigated in UVB-induced wrinkle mouse model mice.</p><p><strong>Results: </strong>PB203 alleviated the UVB-induced reactive oxygen species production, phosphorylation of JNK, ERK, and p38, and formation of AP-1. In addition, PB203 inhibited the decreases in type I collagen and TIMP-1 levels, and the increase in MMP-1 levels in UVB-exposed HaCaT cells. In UVB-induced wrinkle mouse model, PB203 inhibited the decreases in elastin and type I collagen levels as well as the increases in MMP-1 expression, wrinkle formation, and skin dehydration. Furthermore, PB203 increased the expression of filaggrin, HAS1, and HAS2, improving the skin barrier function.</p><p><strong>Conclusion: </strong>Taken together, we found that PB203 is as a potent candidate to serve as a functional ingredient or therapeutic agent to improve UVB-mediated skin aging.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704378","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Skin barrier function relies on three essential components: stratum corneum (SC) lipids, natural moisturizing factors (NMFs), and the acidic pH of the SC surface. Three endogenous pathways contribute to acidity: free fatty acids from phospholipids, trans-urocanic acid from filaggrin (FLG), and the sodium-proton antiporter (NHE1) activity. An acidic SC environment boosts the activity of enzymes to produce ceramides, which are vital for skin health. Conversely, an elevated pH can lead to increased skin infections, reduced lipid-processing enzyme activity, impaired permeability barrier recovery, and compromised integrity and cohesion of the SC due to increased serine protease (SP) activity. Elevated SC pH is observed in neonatal, aged, and inflamed skin. In atopic dermatitis (AD), it results from decreased NMF due to reduced FLG degradation, decreased fatty acids from reduced lamellar body secretion, and reduced lactic acid due to decreased sweating. Moreover, the imbalance between SP and SP inhibitors disrupts barrier homeostasis. However, acidifying the SC can help restore balance and reduce SP activity. Acidic water bathing has been found to be safe and effective for AD. In three different AD murine models, SC acidification prevented the progression of AD to respiratory allergies. In aging skin, a decrease in NHE1 leads to an increased skin pH. Mild acidic skin care products or moisturizers containing NHE1 activators can normalize skin pH and improve barrier function. In conclusion, maintaining the acidity of the SC is crucial for healthy skin barrier function, leading to significant benefits for various skin conditions, such as AD and aging-related skin issues.
{"title":"Importance of Stratum Corneum Acidification to Restore Skin Barrier Function in Eczematous Diseases.","authors":"Eung Ho Choi, Hyun Kang","doi":"10.5021/ad.23.078","DOIUrl":"10.5021/ad.23.078","url":null,"abstract":"<p><p>Skin barrier function relies on three essential components: stratum corneum (SC) lipids, natural moisturizing factors (NMFs), and the acidic pH of the SC surface. Three endogenous pathways contribute to acidity: free fatty acids from phospholipids, trans-urocanic acid from filaggrin (FLG), and the sodium-proton antiporter (NHE1) activity. An acidic SC environment boosts the activity of enzymes to produce ceramides, which are vital for skin health. Conversely, an elevated pH can lead to increased skin infections, reduced lipid-processing enzyme activity, impaired permeability barrier recovery, and compromised integrity and cohesion of the SC due to increased serine protease (SP) activity. Elevated SC pH is observed in neonatal, aged, and inflamed skin. In atopic dermatitis (AD), it results from decreased NMF due to reduced FLG degradation, decreased fatty acids from reduced lamellar body secretion, and reduced lactic acid due to decreased sweating. Moreover, the imbalance between SP and SP inhibitors disrupts barrier homeostasis. However, acidifying the SC can help restore balance and reduce SP activity. Acidic water bathing has been found to be safe and effective for AD. In three different AD murine models, SC acidification prevented the progression of AD to respiratory allergies. In aging skin, a decrease in NHE1 leads to an increased skin pH. Mild acidic skin care products or moisturizers containing NHE1 activators can normalize skin pH and improve barrier function. In conclusion, maintaining the acidity of the SC is crucial for healthy skin barrier function, leading to significant benefits for various skin conditions, such as AD and aging-related skin issues.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861303/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hye Won Hwang, Sunmin Ryou, Jun Hyeong Jeong, Jae Won Lee, Kyung-Ju Lee, Seon Bok Lee, Hyun-Tae Shin, Ji Won Byun, Jeonghyun Shin, Gwang Seong Choi
Background: Alopecia, a benign dermatologic condition affecting both genders, particularly harms female patients due to psychosocial effects. Female pattern hair loss (FPHL), the primary cause of hair loss in women, lacks sufficient Korean epidemiological studies examining its psychosocial aspects.
Objective: This study aimed to explore FPHL's psychosocial impacts, including quality of life (QoL), depression, anxiety, medical consumption, and hair loss factors in Korean women.
Methods: A total of 202 patients with FPHL were interviewed using a validated questionnaire to assess the QoL, psychological impact, and pattern of medical consumption. The severity of hair loss was evaluated using the "basic and specific (BASP) classification" by dermatologists. The Hair-Specific Skindex-29 (HSS29) was used to assess the QoL and Beck depression inventory (BDI), Beck anxiety inventory (BAI) to evaluate psychological aspects, and medical expenses and the number of clinic visits to determine medical consumption.
Results: The global HSS29 score of FPHL was 40.97±18.92, indicating a notable impact on QoL. The mean BDI and BAI scores were 14.47 and 10.06, respectively. In multivariable regression analysis, HSS29, BDI, and BAI scores were most affected by the severity of hair loss (p<0.001).
Conclusion: FPHL damages the psychosocial aspects of patients, such as QoL, depression, and medical consumption, according to the severity of hair loss.
背景:脱发是一种影响男女两性的良性皮肤病,对女性患者造成的社会心理影响尤为严重。女性脱发(FPHL)是导致女性脱发的主要原因,但韩国缺乏足够的流行病学研究来探讨其社会心理方面的问题:本研究旨在探讨 FPHL 对社会心理的影响,包括韩国女性的生活质量(QoL)、抑郁、焦虑、医疗消费和脱发因素:方法:使用有效问卷对 202 名 FPHL 患者进行访谈,评估其生活质量、心理影响和医疗消费模式。皮肤科医生采用 "基本和特异性(BASP)分类法 "对脱发的严重程度进行了评估。毛发特异性指标-29(HSS29)用于评估 QoL,贝克抑郁量表(BDI)和贝克焦虑量表(BAI)用于评估心理方面,医疗费用和就诊次数用于确定医疗消费:FPHL 的 HSS29 总分为(40.97±18.92)分,表明其对 QoL 有显著影响。BDI 和 BAI 平均得分分别为 14.47 分和 10.06 分。在多变量回归分析中,HSS29、BDI 和 BAI 评分受脱发严重程度的影响最大(p 结论:FPHL 对患者的社会心理造成了损害:FPHL会根据脱发的严重程度损害患者的心理社会方面,如生活质量、抑郁和医疗消费。
{"title":"The Quality of Life and Psychosocial Impact on Female Pattern Hair Loss.","authors":"Hye Won Hwang, Sunmin Ryou, Jun Hyeong Jeong, Jae Won Lee, Kyung-Ju Lee, Seon Bok Lee, Hyun-Tae Shin, Ji Won Byun, Jeonghyun Shin, Gwang Seong Choi","doi":"10.5021/ad.23.082","DOIUrl":"10.5021/ad.23.082","url":null,"abstract":"<p><strong>Background: </strong>Alopecia, a benign dermatologic condition affecting both genders, particularly harms female patients due to psychosocial effects. Female pattern hair loss (FPHL), the primary cause of hair loss in women, lacks sufficient Korean epidemiological studies examining its psychosocial aspects.</p><p><strong>Objective: </strong>This study aimed to explore FPHL's psychosocial impacts, including quality of life (QoL), depression, anxiety, medical consumption, and hair loss factors in Korean women.</p><p><strong>Methods: </strong>A total of 202 patients with FPHL were interviewed using a validated questionnaire to assess the QoL, psychological impact, and pattern of medical consumption. The severity of hair loss was evaluated using the \"basic and specific (BASP) classification\" by dermatologists. The Hair-Specific Skindex-29 (HSS29) was used to assess the QoL and Beck depression inventory (BDI), Beck anxiety inventory (BAI) to evaluate psychological aspects, and medical expenses and the number of clinic visits to determine medical consumption.</p><p><strong>Results: </strong>The global HSS29 score of FPHL was 40.97±18.92, indicating a notable impact on QoL. The mean BDI and BAI scores were 14.47 and 10.06, respectively. In multivariable regression analysis, HSS29, BDI, and BAI scores were most affected by the severity of hair loss (<i>p</i><0.001).</p><p><strong>Conclusion: </strong>FPHL damages the psychosocial aspects of patients, such as QoL, depression, and medical consumption, according to the severity of hair loss.</p>","PeriodicalId":94298,"journal":{"name":"Annals of dermatology","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10861302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139704386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}