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Relationship between Shape Retention and X-ray Absorption Value of the Tip of Microcatheters in Neuroendovascular Treatment. 神经内血管治疗中微导管尖端形状保持与 X 射线吸收值之间的关系
Pub Date : 2024-02-26 eCollection Date: 2024-03-01 DOI: 10.1055/s-0043-1760850
Tomotaka Ohshima, Fuminori Ato, Reo Kawaguchi, Naoki Matsuo, Shigeru Miyachi

Objective  We noticed that the X-ray absorption value of the tip of each microcatheter used for aneurysm treatment varied from product to product. We hypothesized that the differences were caused by variations in the metal's density braid, which could be related to the ability of the tip to retain its shape. Methods  The X-ray absorption value of each microcatheter tip was measured. Next, heat forming was performed using a shaping mandrel at 6 mm and 90 degrees to determine whether there was a correlation between the X-ray absorption value and the forming angle. Next, the optimal mandrel angle for forming each microcatheter at 90 degrees was investigated. We also examined the shape retention after 20 times wire insertions into each microcatheter. Conclusion  It was found that the higher the X-ray absorption value, the harder it was for the microcatheter to be formed. The mandrel angle required to form 90 degrees was determined by the X-ray absorption value. The higher the X-ray absorption value, the higher the shape retention of the tip shape. The heat formation and shape-retention conditions of the microcatheter tip were correlated with the X-ray absorption value of the metal braid. Even for unknown microcatheters, the optimum shaping conditions can be inferred from the X-ray absorption value.

目的 我们注意到,用于动脉瘤治疗的每种微导管尖端的 X 射线吸收值因产品而异。我们推测这种差异是由金属密度编织层的变化造成的,而金属密度编织层的变化可能与针尖保持形状的能力有关。方法 测量每个微导管针尖的 X 射线吸收值。然后,使用成型心轴以 6 毫米和 90 度进行热成型,以确定 X 射线吸收值与成型角度之间是否存在相关性。接着,研究了每个微导管在 90 度成型时的最佳心轴角度。我们还检测了将金属丝插入每个微导管 20 次后的形状保持情况。结论 我们发现,X 射线吸收值越高,微导管就越难成型。成型 90 度所需的心轴角度由 X 射线吸收值决定。X 射线吸收值越高,尖端形状的形状保持率越高。微导管尖端的热形成和形状保持条件与金属编织物的 X 射线吸收值相关。即使是未知的微导管,也可以从 X 射线吸收值推断出最佳成型条件。
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引用次数: 0
A Comparative Retrospective Survival Analysis Study of Brain Tumor Patients in Age Less Than or Equal to 50 Years versus More Than 50 Years of Age. 年龄小于或等于 50 岁与大于 50 岁脑肿瘤患者的比较性回顾性生存分析研究。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1777271
Radha Kesarwani, Astha Singh, Mohammad Aqueel, Virendra Singh, Gyan Prakash

Introduction  Approximately 2.5% of fatalities from cancer are caused by brain tumors. Even though there is literature regarding prognostic factor of adult brain tumor, studies often resort to Western demographics. Hence, we conducted this retrospective observational study to compare the demographic characteristics and prognosis in patients of glial tumors in Indian population with histological diagnosis with respect to age. Materials and Methods  A single-center retrospective observational study with 76 patients of glioma who had been treated with surgery combined with radiotherapy with or without chemotherapy was conducted. Group I patients were aged less than or equal to 50 years and group II more than 50 years of age. There were 28 patients in group I and 48 in group II. Postoperatively, external beam radiation therapy was delivered in a conventional fraction (1.8 Gy/fraction, five fractions/week) using telecobalt 60. Ill patients who presented with grade III and IV gliomas received oral chemotherapy temozolomide at a dose of 100 mg daily during course of radiotherapy. Results  The median age of the patients at the time of diagnosis was 45.0 years. More cases of hematologic toxicity occurred in group I than in group II. Total 55 patients were alive at 1-year follow-up (11 in group I and 44 in group II). Conclusion  Grade I and II gliomas were predominant in less than 50 years of age and grade III and IV were predominant in more than 50 years age. Male preponderance was seen in age group of more than 50 years (68%). Overall survival and disease-free survival were better for patients aged less than 50 years.

导言:大约 2.5% 的癌症死亡病例是由脑肿瘤引起的。尽管有文献对成人脑肿瘤的预后因素进行了研究,但这些研究通常采用西方的人口统计学特征。因此,我们开展了这项回顾性观察研究,以比较印度人口中胶质瘤患者的人口统计学特征和预后,以及组织学诊断与年龄的关系。材料与方法 我们对 76 名接受过手术治疗、放疗和化疗或未接受化疗的胶质瘤患者进行了单中心回顾性观察研究。第一组患者年龄小于或等于 50 岁,第二组患者年龄大于 50 岁。I 组有 28 名患者,II 组有 48 名患者。术后,使用远程钴 60 按常规分次(1.8 Gy/次,5 次/周)进行外照射治疗。III 级和 IV 级胶质瘤患者在放疗期间接受了替莫唑胺口服化疗,剂量为每天 100 毫克。结果 患者确诊时的中位年龄为 45.0 岁。第一组发生血液学毒性的病例多于第二组。共有 55 名患者在 1 年的随访中存活(I 组 11 人,II 组 44 人)。结论 I 级和 II 级胶质瘤主要发生在 50 岁以下的患者中,III 级和 IV 级胶质瘤主要发生在 50 岁以上的患者中。50 岁以上年龄组中男性占多数(68%)。50 岁以下患者的总生存率和无病生存率较高。
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引用次数: 0
Contrast-Induced Encephalopathy after Endovascular Treatment: Two Case Reports. 血管内治疗后对比度诱发脑病:两个病例报告。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1776991
Dragan Jankovic, Riki Tanaka, Kento Sasaki, Kyosuke Miyatani, Sachin Chemate, Mayank Nakipuria, Takamitsu Tamura, Fuminari Komatsu, Yasuhiro Yamada, Yoko Kato

Contrast-induced encephalopathy (CIE) is a rare neurological complication that occurs after the use of contrast medium in various angiographic procedures. Symptoms can be different, from headache to severe neurological deficit and coma. In the articles published to date, symptoms appeared immediately after application of contrast agent or within 24 hours. Here we present two cases of patients in whom CIE developed delayed after endovascular treatment.

造影剂诱发脑病(CIE)是一种罕见的神经系统并发症,在各种血管造影术中使用造影剂后都会发生。症状多种多样,从头痛到严重的神经功能缺损和昏迷。在迄今发表的文章中,症状都是在使用造影剂后立即出现或在 24 小时内出现。这里我们介绍两例在血管内治疗后延迟出现CIE的患者。
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引用次数: 0
Spontaneous Subdural Empyema: A Case Report. 自发性硬膜下气肿:病例报告。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1777273
Deep Dutta, Shameem Ahmed, Abhigyan Borkotoky

Subdural empyema is the collection of purulent material between the dura mater and arachnoid. Subdural empyema most often occurs due to the direct extension of local infection. But spontaneous subdural empyema is a rare entity. In literature, not many cases of spontaneous subdural empyema by Escherichia coli are reported. Here we report a case of spontaneous subdural empyema along with a review of literature who was previously treated on the suspicion of encephalitis with urinary tract infection and then brought to our hospital.

硬膜下积液是硬脑膜和蛛网膜之间的脓性物质聚集。硬膜下积液多因局部感染直接蔓延所致。但自发性硬膜下气肿并不多见。文献中关于大肠埃希菌引起的自发性硬膜下气肿的报道并不多。在此,我们报告了一例自发性硬膜下气肿病例,并对文献进行了回顾,该病例曾因怀疑脑炎合并尿路感染而接受治疗,后被送至我院。
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引用次数: 0
Posterior Instrumentation of Cervical Spine: A Bibliometric Analysis of Trends in Publication. 颈椎后路器械:对出版趋势的文献计量分析。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1777274
Vishal Kumar, Vikash Raj, Sitanshu Barik, Richa Richa

Aim  The aim of this study was to perform a bibliometric analysis of the articles published on posterior instrumentation of cervical spine and to study the general publishing trends over the years in this topic in terms of journals, authors, topics, keywords, collaborating countries, etc. Material and Methods  Articles were searched on the web of science using appropriate keywords. A bibliometric analysis was performed using Bibliometrix R package Results  A total of 1,953 studies were identified between 1991 and 2023 including 1,782 articles and 171 reviews from 198 sources. A total of 3,421 author's keywords were used by 6,725 authors. Thirty-four documents are single authored. The average co-author per document is 5.63. The average citation per document is 22.62. There is international co-authorship in 13.11% documents. RM Xu and Sonntag VKH have maximum publications ( n  = 28). The "Spine" journal has the maximum number of publications ( n  = 335) and best H index of 64. United States has maximum number of publications ( n  = 1,720) and citations ( n  = 19,573). Publication by Harms et al in the "Spine" in 2001 has the highest global ( n  = 956) & local ( n  = 272) citations. Three-dimensional printing and atlantoaxial fixation are emerging trends. Conclusion  The findings of this study enhance the knowledge on the topic of posterior instrumentation of cervical spine and shall guide the trends and directions of future research and innovation.

目的 本研究旨在对已发表的有关颈椎后路器械的文章进行文献计量分析,并从期刊、作者、主题、关键词、合作国家等方面研究该主题多年来的总体出版趋势。材料与方法 使用适当的关键词在科学网上搜索文章。使用 Bibliometrix R 软件包进行文献计量分析 结果 在 1991 年至 2023 年期间,共发现 1 953 项研究,包括来自 198 个来源的 1 782 篇文章和 171 篇综述。共有 6,725 位作者使用了 3,421 个作者关键词。有 34 份文件为单人撰写。每篇文献的平均合著者为 5.63 人。每篇文献的平均引用次数为 22.62 次。13.11%的文档为国际合著。RM Xu和Sonntag VKH发表的论文最多(n = 28)。脊柱 "期刊发表的论文数量最多(n = 335),H 指数最高(64)。美国的论文数量(n = 1,720)和引用次数(n = 19,573)最多。Harms 等人 2001 年在《脊柱》上发表的论文在全球(n = 956)和本地(n = 272)的引用次数最多。三维打印和寰枢椎固定是新兴趋势。结论 本研究的结果增进了人们对颈椎后路器械的了解,并将引导未来研究和创新的趋势和方向。
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引用次数: 0
Postoperative CSF Leak: Blood Patch-A New Avenue. 术后 CSF 渗漏:血贴--一条新路
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1768599
Geover Lobo, Sarita R J Lobo

Introduction  Cerebrospinal fluid leak (CSF) after a neurosurgical procedure is a known complication that may result in bad outcomes (1). The incidence of CSF leak varies based on the site involved; it ranges from 4 to 32% for transsphenoidal to posterior fossa procedures. The costs involved in treating postoperative CSF leaks increases exponentially that becomes a barrier in continuing optimum treatment. There are many studies that compare the different treatment modalities and even use of sealing agents but none give an algorithm of management. Our study aims at known technique that can help to treat these kinds of low-pressure CSF leaks. Materials and Methods  This was a prospective study done over a period of 5 years from January 2014 to January 2019. All patients who underwent procedures in which durotomy was done were included in the study. Results  A total of six patients were enrolled for the study. The duration of the study spanned 5 years from January 2014 to January 2019. All the patients after taking informed consent underwent the necessary investigations and a blood patch was done. Five of the patients the CSF stopped but in one patient it persisted. This patient again underwent investigation and under image guidance another blood patch was put after which the CSF leak stopped. Conclusion  Blood patch under imaging guidance is a safe and simple technique. The success rates of cessation of CSF leaks are good. Also, it is a cost-effective method using an autograft (patient's blood).

导言神经外科手术后脑脊液漏(CSF)是一种已知的并发症,可能导致不良后果(1)。脑脊液漏的发生率因手术部位而异,经蝶后窝手术的发生率从 4% 到 32% 不等。治疗术后 CSF 漏所需的费用呈指数增长,成为继续最佳治疗的障碍。有许多研究比较了不同的治疗方法,甚至是密封剂的使用,但都没有给出处理方法。我们的研究旨在了解有助于治疗这类低压 CSF 漏的技术。材料和方法 这是一项前瞻性研究,从 2014 年 1 月至 2019 年 1 月,为期 5 年。研究纳入了所有接受过硬脑膜切开术的患者。结果 共有 6 名患者被纳入研究。研究时间从 2014 年 1 月至 2019 年 1 月,为期 5 年。所有患者在获得知情同意后都接受了必要的检查,并进行了血贴。其中五名患者的 CSF 停止了,但一名患者的 CSF 仍在持续。这名患者再次接受了检查,并在影像引导下再次进行了血贴,之后 CSF 渗漏停止了。结论 影像引导下的血贴是一种安全、简单的技术。停止 CSF 渗漏的成功率很高。此外,使用自体移植物(患者的血液)也是一种经济有效的方法。
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引用次数: 0
Atlantoaxial Instability with Persistent Second Intersegmental Artery. 第二节间动脉持续存在的寰枢椎失稳。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1776050
Batuk Diyora, Ravi Wankhade, Kavin Devani, Anup Purandare, Prakash Palave, Sagar Gawali

Understanding the anatomy of the vertebral artery is essential while manipulating the craniovertebral joint during surgery. Its anomalous course in congenital atlantoaxial dislocation makes it more vulnerable to injury. Preoperative dedicated computed tomography (CT) angiography helps identify the artery's position and plan for surgical procedure. A 13-year-boy presented with neck pain and spastic quadriparesis for 1 year. Radiological imaging of the craniovertebral junction revealed atlantoaxial instability with basilar invagination. His CT angiography of neck and brain vessels revealed an anomalous course of the vertebral artery due to a persistent second intersegment artery. He underwent posterior atlantoaxial fixation after mobilization of the vertebral artery. His clinical condition significantly improved after surgery. We report a case of management of an atlanto axial dislocation with persistent second intersegment artery and describe the role of vertebral artery mobilization during surgery.

在手术过程中操作颅椎关节时,了解椎动脉的解剖结构至关重要。椎动脉在先天性寰枢脱位中的异常走向使其更容易受伤。术前专用的计算机断层扫描(CT)血管造影有助于确定动脉的位置并制定手术计划。一名 13 岁男孩因颈部疼痛和痉挛性四肢瘫痪就诊 1 年。颅椎骨交界处的放射成像显示寰枢椎不稳,基底动脉内陷。颈部和脑血管的 CT 血管造影显示,由于第二节间动脉持续存在,椎动脉走向异常。椎动脉移位后,他接受了后寰枢椎固定术。术后他的临床状况明显改善。我们报告了一例寰枢脱位伴第二节间动脉持续存在的病例,并阐述了椎动脉动员在手术中的作用。
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引用次数: 0
A Case-Based Review of Management of CNS Melioidosis. 以病例为基础的中枢神经系统梅里亚病管理回顾。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1776736
Debajyoti Datta, Arunkumar Sekar, Ashis Patnaik, Srujana Mohanty
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引用次数: 0
Circular Configuration of Torcular Herophili Presenting as Childhood Headache: 2D Computational Fluid Dynamic Analysis with a Proposed Mechanism. 表现为儿童头痛的环形嗜疱疹病毒环形结构:二维计算流体动力学分析与拟议机制。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1776301
Debajyoti Datta, Arunkumar Sekar, Ashis Patnaik

This case report presents a rare anatomical variant of the torcular Herophili, characterized by a circular configuration and the absence of the left transverse sinus. A 12-year-old child presented with intermittent holocranial headaches, and imaging revealed the circular torcular Herophili along with mild ventricular enlargement. The straight sinus drained into the left side of the circular torcular Herophili. Following lumbar puncture and cerebrospinal fluid (CSF) drainage, the child experienced symptom improvement. During a 6-month follow-up, the patient remained asymptomatic, without further headaches or academic disruptions. Similar to a previously reported case, the circular torcular Herophili with unilateral absent transverse sinus may be associated with impaired CSF absorption due to altered blood flow through abnormal venous anatomy. We performed two-dimensional computational fluid dynamic analysis of simulated flow through a synthetic model and showed that this circular configuration is associated with venous stasis. The venous stasis in the sinus may impair CSF absorption through the arachnoid granulations causing hydrocephalus and explaining the headache. Close monitoring and follow-up are recommended for patients with this variant. Further investigation is needed to better understand the clinical implications and underlying mechanisms of such torcular Herophili variations.

本病例报告介绍了一种罕见的环形嗜疱疹解剖变异,其特征是环形结构和左侧横窦缺失。一名 12 岁的儿童因间歇性全颅骨头痛就诊,影像学检查发现他患有环形环状嗜疱疹,同时伴有轻度脑室扩大。直窦引流至环状蝶窦左侧。腰椎穿刺和脑脊液引流后,患儿的症状有所改善。在 6 个月的随访中,患者仍无症状,没有再出现头痛或学习障碍。与之前报道的病例类似,圆形环状疱疹伴单侧横窦缺失可能与异常静脉解剖结构导致的血流改变引起的 CSF 吸收障碍有关。我们对通过合成模型的模拟血流进行了二维计算流体动力学分析,结果表明这种环形结构与静脉瘀血有关。静脉窦中的静脉瘀血可能会影响 CSF 通过蛛网膜肉芽的吸收,导致脑积水,从而引起头痛。建议对该变异型患者进行密切监测和随访。要想更好地了解这种蝶形希罗菲里变异的临床意义和潜在机制,还需要进一步的研究。
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引用次数: 0
RoboticScope-Assisted Microanastomosis in a Chicken Leg Model. 鸡腿模型中的机器人窥镜辅助微吻合术
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1776794
Adi Ahmetspahic, Eldin Burazerovic, Dragan Jankovic, Eleonora Kujaca, Hana Rizvanovic, Ibrahim Omerhodzic, Haso Sefo, Nermir Granov

Background  Many recent studies show that exoscopes are safe and effective alternatives to operating microscopes (OM). Developments of robotics and automation are present in neurosurgery with the appearance of a newer device such as RoboticScope (RS) exoscope with a digital three-dimensional (3D) image and a head-mounted display. The body of the RS is connected to a six-axis robotic arm that contains two video cameras, and serves as stereovision. This robotic arm allows accurate 3D camera motions over the field of view, giving the user a great degree of freedom in viewpoint selection. The surgeons may specify the direction and speed of the robotic arm using simple head movements when the foot pedal is pressed. Since its development in 2020, the RS has occasionally been used in neurosurgery for a multitude of procedures. Methods  This study showcases vessel microanastomosis training on chicken legs using the RS. The aim of this study is to demonstrate the feasibility of the RS without a comparative analysis of the standard OM. The study was conducted in 2023 during a month-long trial period of the device at the Department of Neurosurgery of the Clinical Center of the University of Sarajevo. All procedures including RS-assisted anastomosis were performed by a neurosurgeon in anastomosis training (A.A.) supervised by a senior vascular neurosurgeon (E.B.). For the purpose of the study, we evaluated occlusion time in minutes, bypass patency with iodine, and overall satisfaction of the trainee in terms of light intensity, precision of automatic focus, mobility of the device, ergonomics, and convenience of the helmet. Results  Ten RS-assisted microanastomoses were performed by interrupted suturing technique with 10.0 nylon thread. Bypass training included seven "end-to-side," two "end-to-end," and one "side-to-side" microanastomoses. The smallest vessel diameter was 1 mm. Occlusion time improved by training from 50 to 24 minutes, with contrast patency of the anastomoses in all cases without notable leakage of the contrast, except one case. Complete satisfaction of the trainee was achieved in 7 out of 10 cases. During this period, we also performed different RS-assisted surgeries including a single indirect bypass, convexity brain tumor resection, and microdiscectomies. Conclusion  RS provides a new concept for microanastomosis training as an alternative or adjunct to the standard microscope. We found a full-time hands-on microsuturing without the need for manual readjustment of the device as an advantage as well as instant depth at automatic zooming and precise transposition of the focus via head movements. However, it takes time to adapt and get used to the digital image. With the evolution of the device helmet's shortcomings, the RS could represent a cutting-edge method in vessel microanastomosis in the future. Nevertheless, this article represents one of the first written reports on microanastomosis training on an an

背景 最近的许多研究表明,外窥镜是手术显微镜(OM)安全有效的替代品。随着机器人和自动化技术的发展,神经外科出现了一种较新的设备,如带有数字三维(3D)图像和头戴式显示器的机器人外窥镜(RS)。RS 的机身与一个六轴机械臂相连,机械臂上装有两台摄像机,用作立体视觉。该机械臂可在视野内进行精确的三维摄像运动,使用户在选择视点时有很大的自由度。外科医生可以在按下脚踏板时,通过简单的头部运动来指定机械臂的方向和速度。自 2020 年开发以来,RS 偶尔会用于神经外科的多种手术。方法 本研究展示了使用 RS 在鸡腿上进行血管微吻合训练。本研究旨在展示 RS 的可行性,而不对标准 OM 进行比较分析。这项研究于 2023 年在萨拉热窝大学临床中心神经外科进行,当时该设备正在进行为期一个月的试用。包括 RS 辅助吻合术在内的所有手术均由一名接受过吻合术培训的神经外科医生(A.A.)在一名资深血管神经外科医生(E.B.)的指导下完成。在研究中,我们评估了以分钟为单位的闭塞时间、碘伏下的旁路通畅度,以及受训者在光照强度、自动聚焦的精确度、设备的移动性、人体工程学和头盔的便利性等方面的总体满意度。结果 使用 10.0 尼龙线,通过间断缝合技术完成了 10 例 RS 辅助微吻合术。旁路训练包括七次 "端对端"、两次 "端对端 "和一次 "侧对侧 "微吻合。最小血管直径为 1 毫米。通过培训,闭塞时间从 50 分钟缩短到 24 分钟,除一例外,所有吻合口均造影剂通畅,造影剂无明显渗漏。在 10 个病例中,有 7 个让受训者完全满意。在此期间,我们还进行了不同的 RS 辅助手术,包括单个间接分流术、凸面脑肿瘤切除术和显微椎间盘切除术。结论 RS 为显微吻合术培训提供了一个新概念,可作为标准显微镜的替代或辅助工具。我们发现,无需手动重新调整设备即可进行全时显微缝合的优势,以及自动变焦和通过头部移动精确转移焦点的即时深度。不过,适应和习惯数字图像需要时间。随着设备头盔缺点的不断改进,RS 将成为未来血管微吻合的尖端方法。尽管如此,这篇文章代表了使用上述设备在动物模型上进行微吻合训练的首批书面报告之一。
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引用次数: 0
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Asian journal of neurosurgery
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