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Microvascular Decompression versus Radiofrequency Ablation in Trigeminal Neuralgia of the Maxillary and Mandibular Divisions. 上颌和下颌三叉神经痛的微血管减压术与射频消融术。
Pub Date : 2024-05-27 eCollection Date: 2024-06-01 DOI: 10.1055/s-0044-1779516
Hosam-Eldin Abdel-Azim Habib, Mohamed Hamdy Ellakany, Hossam Elnoamany, Ahmed Gabry Elnaggar

Background  Although medical treatment is the mainstay of therapy, in trigeminal neuralgia (TN), patients failing to respond to it make them candidates to ablative or nonablative procedures. Objective  The aim of this study was to compare the outcome of Microvascular decompression (MVD) and radiofrequency (RF) thermocoagulation in the management of TN affecting the mandibular and maxillary divisions. Materials and Methods  Retrospective analysis of the data of 40 patients suffering from intractable classical TN affecting the maxillary or mandibular divisions or both was carried out. Twenty patients were operated upon by MVD of the trigeminal nerve; and 20 had RF ablation of the maxillary or mandibular divisions of the trigeminal nerve or both. Results  In MVD the overall successful outcome was achieved in 16 patients (80%), while the failure was in 4 patients (20%) of which 3 had a fair outcome and 1 patient had a poor outcome. Whereas in RF the overall successful outcome was achieved in 17 patients (85%), while the failure was in 3 patients (15%) of which 2 had a fair outcome and 1 patient had a poor outcome. Outcome was insignificantly different between both groups ( p -value 0.806). Conclusion  MVD and RF ablation represent safe and efficacious surgical choices for addressing TN that encompasses both the mandibular and maxillary divisions. Long-term follow-up studies demonstrate that MVD consistently yields favorable outcomes, establishing it as the preferred primary surgical technique, unless contraindicated by the patient's general health and specific needs.

背景 虽然药物治疗是三叉神经痛(TN)的主要治疗方法,但对药物治疗无效的患者可接受消融或非消融治疗。本研究旨在比较微血管减压术(MVD)和射频热凝术在治疗下颌和上颌三叉神经痛中的疗效。材料和方法 对 40 名上颌或下颌或两者均受影响的难治性典型 TN 患者的数据进行了回顾性分析。20 名患者接受了三叉神经MVD手术;20 名患者接受了三叉神经上颌或下颌分支或两者的射频消融术。结果 16 名患者(80%)的三叉神经MVD手术总体成功,4 名患者(20%)失败,其中 3 名患者效果一般,1 名患者效果不佳。在射频治疗中,17 名患者(85%)获得了总体成功,3 名患者(15%)失败,其中 2 名患者疗效一般,1 名患者疗效较差。两组结果差异不大(P 值为 0.806)。结论 MVD 和射频消融是治疗下颌和上颌TN的安全有效的手术选择。长期随访研究表明,MVD始终能产生良好的疗效,因此,除非患者的总体健康状况和特殊需要有禁忌症,MVD是首选的主要手术技术。
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引用次数: 0
Collision Tumor Composed of Nonfunctioning Pituitary Adenoma and Meningioma in the Sellar Region: Report of a Case and Literature Review. ellar区无功能垂体腺瘤与脑膜瘤的碰撞瘤:病例报告与文献综述。
Pub Date : 2024-05-27 eCollection Date: 2024-06-01 DOI: 10.1055/s-0044-1787117
Sachin Baldawa, Abhay Raikhailkar

Background  The coexistence of two histologically distinct neoplasms in the same area without histological admixture or an intermediate cell population zone represents a rare tumor type called collision tumor. Collision tumor of pituitary adenoma and meningioma has been reported years later following irradiation to pituitary adenoma. However, collision tumor of pituitary adenoma and meningioma in absence of irradiation therapy is extremely uncommon. Case Description  We report an unusual case of collision tumor involving diaphragma sella meningioma and pituitary adenoma in a 50-year-old lady without prior radiation therapy. She presented with visual blurring and impaired field of vision. Her preoperative magnetic resonance imaging (MRI) was suggestive of pituitary adenoma. Total excision of the lesion was performed through endoscopic transsphenoidal route. Histological diagnosis was consistent with collision tumor of pituitary adenoma and meningioma. Conclusion  Collision tumor comprising of nonfunctioning pituitary adenoma and meningioma is extremely rare. Preoperative MRI may not always be able to distinguish these histologically distinct neoplasms. Hence, histopathological examination is necessary to establish the diagnosis. Endoscopic transsphenoidal approach may suffice in excision of these collision tumors. Close follow-up is necessary to detect tumor recurrence. Though the association of these tumors can be coincidental, casual relationship between the occurrence of collision tumors cannot be totally excluded.

背景 两种组织学上不同的肿瘤同时存在于同一部位,没有组织学混杂或中间细胞群区,这是一种罕见的肿瘤类型,称为碰撞瘤。垂体腺瘤和脑膜瘤的碰撞瘤在垂体腺瘤照射多年后才有报道。然而,垂体腺瘤与脑膜瘤碰撞肿瘤在未接受放射治疗的情况下发生,则极为罕见。病例描述 我们报告了一例不同寻常的脑膜膈瘤和垂体腺瘤碰撞肿瘤病例,患者是一位 50 岁的女士,此前未接受过放射治疗。她出现视力模糊和视野受损。术前磁共振成像(MRI)提示她患有垂体腺瘤。通过内窥镜经蝶窦途径对病灶进行了全切除。组织学诊断符合垂体腺瘤和脑膜瘤的碰撞瘤。结论 由无功能垂体腺瘤和脑膜瘤组成的碰撞性肿瘤极为罕见。术前磁共振成像不一定能够区分这些组织学上不同的肿瘤。因此,组织病理学检查是确诊的必要条件。内窥镜经蝶窦方法可能足以切除这些碰撞性肿瘤。需要密切随访以发现肿瘤复发。虽然这些肿瘤的关联可能是偶然的,但不能完全排除碰撞性肿瘤发生之间的偶然关系。
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引用次数: 0
Intradiscal Osteotomy and Bilateral Expandable Transforaminal Interbody Fusion Cages for Iatrogenic Kyphotic Deformity: A Technical Report. 椎间盘内截骨术和双侧可扩张经椎间融合套管治疗先天性駝背畸形:技术报告。
Pub Date : 2024-05-27 eCollection Date: 2024-06-01 DOI: 10.1055/s-0044-1787084
Joseph S Hudson, Andrew Legarreta, Daryl P Fields, Hansen Deng, David J McCarthy, Roberta Sefcik, Nitin Agarwal, David K Hamilton

Objectives  Expandable transforaminal interbody fusion (TLIF) devices have been developed to introduce more segmental lordosis through a narrow operative corridor, but there are concerns about the degree of achievable correction with a small graft footprint. In this report, we describe the technical nuances associated with placing bilateral expandable cages for correction of iatrogenic deformity. Materials and Methods  A 60-year-old female with symptomatic global sagittal malalignment and a severe lumbar kyphotic deformity after five prior lumbar surgeries presented to our institution. We performed multilevel posterior column osteotomies, a L3-4 intradiscal osteotomy, and placed bilateral lordotic expandable TLIF cages at the level of maximum segmental kyphosis. Results  We achieve a 21-degree correction of the patient's focal kyphotic deformity and restoration of the patient global sagittal alignment. Conclusion  This case demonstrates both the feasibility and utility of placing bilateral expandable TLIF cages at a single disc space in the setting of severe focal sagittal malalignment. This technique expands the implant footprint and, when coupled with an intradiscal osteotomy, allows for a significant restoration of segmental lordosis.

目的 可扩张的经椎间孔椎间融合术(TLIF)器械的开发是为了通过狭窄的手术走廊引入更多的节段前凸,但人们担心在移植物足迹较小的情况下可达到的矫正程度。在本报告中,我们介绍了为矫正先天性畸形而放置双侧可扩张骨架的相关技术细节。材料与方法 一名 60 岁女性患者在接受过五次腰椎手术后,出现了无症状的整体矢状位错位和严重的腰椎畸形。我们进行了多层次后柱截骨术、L3-4椎间盘内截骨术,并在最大节段性畸形水平放置了双侧前凸可扩张TLIF笼。结果 我们对患者的病灶畸形进行了 21 度矫正,并恢复了患者的整体矢状对齐。结论 本病例证明了在严重局灶性矢状位不正的情况下,在单椎间盘间隙放置双侧可扩张 TLIF 笼的可行性和实用性。这种技术扩大了植入物的覆盖范围,再加上椎间盘内截骨,可以显著恢复节段前凸。
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引用次数: 0
Fourth Ventricular Rosai-Dorfman Disease Mimicking Intraventricular Tumor in Young Adult: A Rare Case Report. 青壮年第四脑室罗赛-多夫曼病(Rosai-Dorfman Disease Mimicking Intraventricular Tumor):罕见病例报告
Pub Date : 2024-05-27 eCollection Date: 2024-06-01 DOI: 10.1055/s-0044-1787089
Meghana V Chougule, Shankaran Prabhakar, Nikhil Tadwalkar, Atul Ranade

Rosai-Dorfman disease (RDD) or sinus histiocytosis with massive lymphadenopathy can present with or without systemic disease. It is a benign histioproliferative disorder characterized by generalized lymphadenopathy, weakness, anemia, and rarely extranodal involvement. While RDD most commonly affects lymph nodes, extranodal involvement of multiple organs has been reported, including the central nervous system (CNS). However, CNS involvement in RDD is rare and is not well characterized. Isolated involvement of the fourth ventricle is even rarer. Such lesions may be mistaken for intraventricular tumors such as ependymoma or medulloblastoma. This report highlights the necessity to consider RDD as a differential diagnosis in case of intraventricular space-occupying lesion.

罗赛-多夫曼病(RDD)或伴有大量淋巴结病的窦组织细胞增生症可伴有或不伴有全身性疾病。它是一种良性组织增生性疾病,以全身淋巴结病、虚弱、贫血为特征,很少累及结节外。虽然 RDD 最常累及淋巴结,但也有多器官结节外受累的报道,包括中枢神经系统(CNS)。然而,中枢神经系统受累在 RDD 中并不多见,而且特征也不明确。第四脑室的孤立受累更为罕见。此类病变可能被误诊为脑室内肿瘤,如上胚乳瘤或髓母细胞瘤。本报告强调了将 RDD 作为脑室内占位性病变鉴别诊断的必要性。
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引用次数: 0
An Adult Case of Medulloblastoma with Multiple Lung Metastatic Lesions-Case Report and Literature Review. 一例成人髓母细胞瘤伴多发性肺转移病灶--病例报告和文献综述。
Pub Date : 2024-05-27 eCollection Date: 2024-06-01 DOI: 10.1055/s-0044-1787080
Mohammed A Azab

Medulloblastoma (MB) cerebelli is a common brain tumor of the childhood. MB commonly spreads through cerebrospinal fluid; however, there are several reported cases of extracranial spread. The most common sites of extracranial metastasis are bones and bone marrow followed by peritoneum, liver, and lungs. Here, we report a case of pulmonary metastatic lesions of adult cerebellar MB that were discovered 1 year after the primary surgical treatment. We also tried to highlight similar reported cases in the literature.

脑髓母细胞瘤(MB)是一种常见的儿童脑肿瘤。髓母细胞瘤通常通过脑脊液扩散,但也有几例颅外扩散的报道。最常见的颅外转移部位是骨骼和骨髓,其次是腹膜、肝脏和肺部。在此,我们报告了一例成人小脑MB肺转移病灶病例,该病灶是在原发手术治疗一年后发现的。我们还试图强调文献中报道的类似病例。
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引用次数: 0
The Accuracy of the S100B Protein Biomarker in the Prognosis of Patients with Acute Spinal Cord Injury S100B 蛋白生物标志物对急性脊髓损伤患者预后的准确性
Pub Date : 2024-04-16 DOI: 10.1055/s-0043-1771323
Kaveh Haddadi, S. Abediankenari, S. Ehteshami, Abbas Alipour, Hassan Shayan Majd, Hamed Jafarpour, L. Asadian
Introduction The role of some biomarkers such as S100 beta (S100B) has been somewhat known in determining the severity of primary acute spinal cord injury (SCI), and today, it has been the basis of various relevant studies. Therefore, this study estimates the S100B level in serum and cerebrospinal fluid (CSF) in patients with spinal injuries. Methods This was a descriptive-analytic study. In this study, 31 patients with acute SCI referred to Sari Imam Khomeini Hospital, Iran, were recruited. Patients were divided into two groups of complete and incomplete SCI according to the American Spinal Injury Association (ASIA). The S100B concentrations in serum and CSF levels were compared between the two groups. Result There was only significant positive correlation between S100B CSF concentration and complete SCI based on the ASIA criterion, meaning that in cases of complete SCI the S100B CSF concentration was significantly increased correlation coefficient (CC) (cc = 0.529 and p = 0.002). Based on the results of serum S100B protein concentration, 14.70 ng/dL with a sensitivity of 66.7% and specificity of 55% was determined as cutoff for complete SCI. Also, about the CSF S100B protein level variable, concentration of 342.18 ng/dL with 100% sensitivity and 64% specificity was determined as cutoff for complete injury. Conclusion The results of this unique study have shown that S100B were useful markers for predicting the prognosis of patients with acute SCI and cutoff points determined for serum and especially CSF concentrations can differentiate complete and incomplete SCI.
引言 S100 beta(S100B)等生物标志物在确定原发性急性脊髓损伤(SCI)严重程度方面的作用已广为人知,如今它已成为各种相关研究的基础。因此,本研究估计了脊髓损伤患者血清和脑脊液(CSF)中的 S100B 水平。方法 这是一项描述性分析研究。本研究招募了 31 名转诊至伊朗萨里伊玛目霍梅尼医院的急性 SCI 患者。根据美国脊柱损伤协会(ASIA)的标准,患者被分为完全性和不完全性脊柱损伤两组。比较两组患者血清和脑脊液中的 S100B 浓度。结果 根据 ASIA 标准,S100B CSF 浓度与完全性 SCI 之间存在明显的正相关,即完全性 SCI 患者的 S100B CSF 浓度相关系数(CC)明显升高(cc = 0.529,p = 0.002)。根据血清 S100B 蛋白浓度的结果,14.70 ng/dL 被确定为完全性 SCI 的临界值,敏感性为 66.7%,特异性为 55%。此外,关于脑脊液 S100B 蛋白水平变量,342.18 纳克/分升的浓度被确定为完全损伤的临界值,敏感性为 100%,特异性为 64%。结论 这项独特研究的结果表明,S100B 是预测急性 SCI 患者预后的有用标记物,血清尤其是 CSF 浓度的临界点可区分完全性和不完全性 SCI。
{"title":"The Accuracy of the S100B Protein Biomarker in the Prognosis of Patients with Acute Spinal Cord Injury","authors":"Kaveh Haddadi, S. Abediankenari, S. Ehteshami, Abbas Alipour, Hassan Shayan Majd, Hamed Jafarpour, L. Asadian","doi":"10.1055/s-0043-1771323","DOIUrl":"https://doi.org/10.1055/s-0043-1771323","url":null,"abstract":"\u0000 Introduction The role of some biomarkers such as S100 beta (S100B) has been somewhat known in determining the severity of primary acute spinal cord injury (SCI), and today, it has been the basis of various relevant studies. Therefore, this study estimates the S100B level in serum and cerebrospinal fluid (CSF) in patients with spinal injuries.\u0000 Methods This was a descriptive-analytic study. In this study, 31 patients with acute SCI referred to Sari Imam Khomeini Hospital, Iran, were recruited. Patients were divided into two groups of complete and incomplete SCI according to the American Spinal Injury Association (ASIA). The S100B concentrations in serum and CSF levels were compared between the two groups.\u0000 Result There was only significant positive correlation between S100B CSF concentration and complete SCI based on the ASIA criterion, meaning that in cases of complete SCI the S100B CSF concentration was significantly increased correlation coefficient (CC) (cc = 0.529 and p = 0.002). Based on the results of serum S100B protein concentration, 14.70 ng/dL with a sensitivity of 66.7% and specificity of 55% was determined as cutoff for complete SCI. Also, about the CSF S100B protein level variable, concentration of 342.18 ng/dL with 100% sensitivity and 64% specificity was determined as cutoff for complete injury.\u0000 Conclusion The results of this unique study have shown that S100B were useful markers for predicting the prognosis of patients with acute SCI and cutoff points determined for serum and especially CSF concentrations can differentiate complete and incomplete SCI.","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":"91 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140695689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Comparison of Perioperative Complications and Outcomes in Patients Undergoing Cerebral Aneurysm Clipping Performed Ultra-Early (≤ 24 hours) versus Late (> 24 hours): A 7-Year Retrospective Study of 302 Patients 超早期(≤ 24 小时)与晚期(> 24 小时)脑动脉瘤夹闭术患者围手术期并发症和预后的比较:302例患者的7年回顾性研究
Pub Date : 2024-04-16 DOI: 10.1055/s-0043-1769758
S. Muangman, M. Raksakietisak, Kamheang Vacharaksa, Kattiya Manomatangkul, Ekawut Chankaew, Chayasorn Kotchasit, Penpuk Deepinta, Sirima Phoowanakulchai
Objectives The intracerebral aneurysm with subarachnoid hemorrhage (SAH) has a high morbidity and mortality rate. This study aimed to compare the incidences of perioperative complications in ultra-early surgery (within 24 hours) with those in late surgery (> 24 hours). Methods Retrospective data were reviewed for 302 patients who underwent craniotomies with aneurysm clipping between January 2014 and December 2020. Perioperative data were obtained from the medical records and reviewed by the investigators. The complications were compared between ultra-early and late operations. We were interested in major complications such as delayed ischemic neurologic deficit (DIND), intraoperative aneurysm rupture (IAR), and anesthesia-related complications. The short-term (in hospital) and long-term (1 year) outcomes in patients with or without DIND and IAR were compared. The collected data was statistically analyzed. Results Three hundred and two patients were analyzed, and 264 patients had completed follow-up. The ultra-early cases (150 patients) had a higher American Society of Anesthesiologists physical status, a lower Glasgow Coma Scale, and higher Hunt and Hess scales. The surgeons operated on more cases of the anterior cerebral artery as ultra-early operations. The incidence rates of DIND, IAR, severe hemodynamic instability, and cardiac arrest were 5.6, 8.3, 6.3, and 0.3%, respectively, which were not different between groups. However, the reintubation rate was higher in the ultra-early surgery cases (0 vs. 3.3%, p = 0.023). The DIND and IAR patients had poorer short-term (in hospital) outcomes. Conclusions There were no differences in major complications between ultra-early and late craniotomy with aneurysm clipping. However, the reintubation rate was strikingly higher in the ultra-early group. Patients with major complications had early, unfavorable outcomes.
目的 脑内动脉瘤合并蛛网膜下腔出血(SAH)的发病率和死亡率都很高。本研究旨在比较超早期手术(24 小时内)和晚期手术(24 小时以上)围手术期并发症的发生率。方法 回顾性分析 2014 年 1 月至 2020 年 12 月间 302 名接受开颅动脉瘤夹闭术患者的数据。研究人员从病历中获取围手术期数据并进行审查。我们对超早期手术和晚期手术的并发症进行了比较。我们关注的是主要并发症,如延迟缺血性神经功能缺损(DIND)、术中动脉瘤破裂(IAR)和麻醉相关并发症。比较了有无 DIND 和 IAR 患者的短期(住院)和长期(1 年)预后。对收集的数据进行了统计分析。结果 分析了 320 名患者,其中 264 名患者完成了随访。超早期病例(150 例)的美国麻醉医师协会身体状况较好、格拉斯哥昏迷量表较低、亨特和赫斯量表较高。外科医生对更多的大脑前动脉病例进行了超早期手术。DIND、IAR、严重血流动力学不稳定和心脏骤停的发生率分别为5.6%、8.3%、6.3%和0.3%,组间无差异。然而,超早期手术病例的再插管率更高(0 vs. 3.3%,P = 0.023)。DIND和IAR患者的短期(住院)预后较差。结论 超早期和晚期开颅动脉瘤夹闭术的主要并发症没有差异。但是,超早期组的再插管率明显更高。出现主要并发症的患者早期结局不佳。
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引用次数: 0
Paraspinal Desmoid Tumor in a Pediatric Patient with No Surgical History: A Case Report 无手术史的小儿脊柱旁蝶窦瘤:病例报告
Pub Date : 2024-04-16 DOI: 10.1055/s-0043-1771366
Aneek Patel, Gregory Varga, A. Mallela, Hussam Abou-Al-Shaar, Andrew Bukowinski, Erica Mamauag, Eduardo V. Zambrano, Stephanie Greene
Desmoid tumors are locally aggressive, benign neoplasms originating in connective tissues. Although the exact pathophysiology remains unknown, antecedent trauma or surgery are believed to be important contributing factors. The occurrence of paraspinal desmoid tumor in pediatric patients is extremely uncommon. Here, we present an exceedingly rare case of a pediatric patient with no surgical or family history who developed a paraspinal desmoid tumor.A 9-year-old female patient presented with 4 months of progressive back pain, right lower extremity weakness, and numbness. Spinal imaging revealed a left epidural paraspinal mass compressing her thoracic spinal cord and extending into the left thoracic cavity. A multidisciplinary approach with neurosurgery and thoracic surgery enabled gross total resection of the lesion. The patient had complete resolution of her symptoms with no signs of residual tumor on postoperative imaging. Pathology revealed a desmoid tumor that avidly stained for beta-catenin. On her last follow-up, she developed a recurrence, to which she was started on sorafenib therapy.Desmoid tumors are rare connective tissue neoplasms that often occur after local tissue trauma, such as that caused by surgery. This report presents a rare case of a pediatric paraspinal desmoid tumor that occurred in a patient with no surgical or family history. Such tumors should undergo surgical resection for symptomatic relief and tissue diagnosis. Close clinical and radiographic surveillance are essential in these patients due to the high recurrence rates of desmoid tumor.
蝶形细胞瘤是一种起源于结缔组织的局部侵袭性良性肿瘤。虽然确切的病理生理学尚不清楚,但据信创伤或手术是重要的诱发因素。脊柱旁类脂膜瘤在儿科患者中极为罕见。在此,我们将介绍一例极为罕见的病例,该病例是一名无手术史或家族史的儿童患者患上了脊柱旁类脂膜瘤。一名 9 岁的女性患者因 4 个月的进行性背痛、右下肢无力和麻木就诊。脊柱造影显示,左侧硬膜外脊柱旁肿块压迫胸脊髓并延伸至左胸腔。神经外科和胸外科采用多学科方法,对病灶进行了彻底切除。患者症状完全缓解,术后影像学检查未发现肿瘤残留迹象。病理结果显示,患者患的是脱模瘤,β-catenin 染色阳性。蝶形细胞瘤是一种罕见的结缔组织肿瘤,通常发生在局部组织创伤后,如手术造成的创伤。本报告介绍了一例罕见的小儿脊柱旁类脂膜瘤病例,患者无手术史或家族史。此类肿瘤应进行手术切除,以缓解症状并进行组织诊断。由于类脂膜瘤的复发率较高,对这类患者进行密切的临床和影像学监测至关重要。
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引用次数: 0
Comparison of the Prognostic Accuracy of Full Outline of Unresponsiveness (FOUR) Score with Glasgow Coma Scale (GCS) Score among Patients with Traumatic Brain Injury in a Tertiary Care Center 在一家三级医疗中心的创伤性脑损伤患者中比较无反应全轮廓(FOUR)评分与格拉斯哥昏迷量表(GCS)评分的预后准确性
Pub Date : 2024-04-16 DOI: 10.1055/s-0044-1779515
Indrani Chattopadhyay, Lakshmi Ramamoorthy, Manoranjitha Kumari, K.T. Harichandrakumar, H. T. Lalthanthuami, Rani Subramaniyan
Objectives The Glasgow Coma Scale (GCS) is widely used and considered the gold standard in assessing the consciousness of patients with traumatic brain injury. However, some significant limitations, like the considerable variations in interobserver reliability and predictive validity, were the reason for developing the Full Outline of Unresponsiveness (FOUR) score. The current study aims to compare the prognostic accuracy of the FOUR score with the GCS score for in-hospital mortality and morbidity among patients with traumatic brain injury. Materials and Methods A prospective cohort study was conducted, where 237 participants were selected by consecutive sampling from a tertiary care center. These patients were assessed with the help of GCS and FOUR scores within 6 hours of admission, and other clinical parameters were also noted. The level of consciousness was checked every day with the help of GCS and FOUR scores until their last hospitalization day. Glasgow Outcome Scale was used to assess their outcome on the last day of hospitalization. The GCS and FOUR scores were compared, and data were analyzed by descriptive and inferential statistics. The chi-square test, independent Student's t-test, and receiver operating characteristic analysis were used for inferential analysis. Results The area under the curve (AUC) for the GCS score at the 6th hour for predicting mortality was 0.865 with a cutoff value of 5.5, and it yields a sensitivity of 87% and a specificity of 64%. The AUC for FOUR scores at the 6th hour for predicting the mortality was 0.893, with a cutoff value of 5.5, and it yields a sensitivity of 87% and a specificity of 73%. Conclusion The current study shows that, as per the AUC of GCS and FOUR scores, their sensitivity was equal, but specificity was higher in the FOUR score. So, the FOUR score has higher accuracy than the GCS score in the prediction of mortality among traumatic brain injury patients.
目的 格拉斯哥昏迷量表(GCS)被广泛使用,被认为是评估脑外伤患者意识的黄金标准。然而,该量表存在一些明显的局限性,如观察者之间的可靠性和预测有效性存在相当大的差异,这也是开发 "反应迟钝全纲"(FOUR)量表的原因。本研究旨在比较 FOUR 评分与 GCS 评分对创伤性脑损伤患者院内死亡率和发病率的预后准确性。材料与方法 本研究采用前瞻性队列研究方法,从一家三级医疗中心连续抽样选出 237 名参与者。这些患者在入院 6 小时内接受了 GCS 和 FOUR 评分评估,并记录了其他临床参数。在最后一个住院日之前,每天使用 GCS 和 FOUR 评分检查患者的意识水平。格拉斯哥结果量表用于评估住院最后一天的结果。对 GCS 和 FOUR 评分进行比较,并通过描述性和推论性统计对数据进行分析。推理分析采用卡方检验、独立学生 t 检验和接收者操作特征分析。结果 第 6 小时 GCS 评分预测死亡率的曲线下面积(AUC)为 0.865,临界值为 5.5,灵敏度为 87%,特异度为 64%。FOUR 评分在第 6 小时预测死亡率的 AUC 为 0.893,临界值为 5.5,灵敏度为 87%,特异度为 73%。结论 本次研究表明,根据 GCS 和 FOUR 评分的 AUC 值,两者的灵敏度相同,但 FOUR 评分的特异性更高。因此,在预测脑外伤患者的死亡率方面,FOUR 评分比 GCS 评分更准确。
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引用次数: 0
Brachioradial Pruritus Caused by Cervical Disc Herniation Precipitated by Trauma Treated with Anterior Cervical Discectomy and Fusion: Report of Two Cases and Review of the Literature 外伤导致的颈椎间盘突出症引起的肱动脉瘙痒,经颈椎椎间盘前路切除术和融合术治疗:两例病例报告及文献综述
Pub Date : 2024-04-09 DOI: 10.1055/s-0043-1772760
Nicholas S. Hernandez, James L. Rogers, Martin H. Pham
Brachioradial pruritis (BRP) is a rare form of dermatomal pruritis that appears to be caused both by cervical radiculopathy and exposure to ultraviolet-light, although the exact pathophysiology for the manifestation of these symptoms remains to be determined. A diagnosis of BRP is typically confirmed with the “ice-pack” test and evidence of cervical spine pathology using magnetic resonance imaging. Treatment options consist of application of ice, reduction in sun exposure, and topical capsaicin, antiepileptics, or tricyclic antidepressants. Patients with refractory symptoms and cervical spine pathology may be candidates for surgical decompression, particularly at the C5 and C6 levels. However, there are currently no established guidelines to treat BRP, or surgical procedures that have shown to be superior. Here, we report two cases of cervical disc herniations after traumatic events that presented as BRP. Both cases were successfully treated with anterior cervical discectomy and fusion with complete resolution of symptoms.
肱动脉瘙痒症(BRP)是一种罕见的皮肤瘙痒症,似乎是由颈椎病和紫外线照射引起的,但这些症状表现的确切病理生理学仍有待确定。BRP的诊断通常需要通过 "冰袋 "试验和磁共振成像检查颈椎病变的证据来确认。治疗方法包括冰敷、减少日晒、局部使用辣椒素、抗癫痫药或三环类抗抑郁药。症状难治且颈椎有病变的患者可能需要进行手术减压,尤其是在 C5 和 C6 水平。然而,目前还没有治疗BRP的既定指南,也没有显示出优越性的手术方法。在此,我们报告了两例在创伤事件后表现为BRP的颈椎间盘突出症。两例患者均成功接受了颈椎间盘前路切除术和融合术,症状完全缓解。
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引用次数: 1
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Asian journal of neurosurgery
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