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A Comprehensive Review of Pyogenic Spondylitis Management for Neurosurgeons. 神经外科医生对化脓性脊柱炎治疗的全面回顾。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1777272
Masatoshi Yunoki

Older populations have been increasing recently, resulting in an increase in cases of pyogenic spondylitis. Neurosurgeons who frequently treat the elderly are at a higher risk of encountering this condition. Therefore, this article provides a summary of the literature and our experience to help neurosurgeons effectively manage pyogenic osteomyelitis. It is important not to rule out pyogenic spondylosis when examining a patient with back pain, even in the absence of a fever. This is because the chronic type is common, easily overlooked, and early diagnosis and treatment are crucial. Empirical antibiotics should be avoided in cases where blood culture and biopsy are negative, to prevent microbial resistance and an increase in difficult-to-treat cases. Biopsies, such as computed tomography-guided percutaneous biopsy and full endoscopic debridement and drainage, should be attempted. Currently, 6 weeks of parenteral antibiotic therapy is the main treatment for pyogenic spondylitis. Surgical treatment is recommended if this method is ineffective. However, in the early stages, full endoscopic debridement and drainage and percutaneous pedicle screw fixation are optional.

近来老年人口不断增加,导致化脓性脊柱炎病例增多。经常治疗老年人的神经外科医生遇到这种疾病的风险较高。因此,本文总结了相关文献和我们的经验,以帮助神经外科医生有效处理化脓性骨髓炎。在检查背痛患者时,即使没有发烧,也不能排除化脓性脊柱炎,这一点非常重要。这是因为慢性类型的化脓性脊柱炎很常见,容易被忽视,早期诊断和治疗至关重要。在血液培养和活组织检查均为阴性的病例中,应避免使用经验性抗生素,以防止微生物产生耐药性和增加难以治疗的病例。应尝试进行活检,如计算机断层扫描引导下的经皮活检和内窥镜下的全面清创和引流。目前,化脓性脊柱炎的主要治疗方法是肠外抗生素治疗 6 周。如果这种方法无效,建议采用手术治疗。不过,在早期阶段,可选择完全内窥镜清创引流术和经皮椎弓根螺钉固定术。
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引用次数: 0
Endovascular Management of Falcine Dural Arteriovenous Fistula-A Case Report and Review of Literature. 法氏硬脑膜动静脉瘘的血管内治疗--病例报告和文献综述。
Pub Date : 2023-12-29 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1776302
Batuk Diyora, Kavin Devani, Anup Purandare, Ravi Wankhade, Prakash Palave, Pallavi Shukla, Gagan Dhall

Cranial dural arteriovenous (AV) fistulas are abnormal connections between the branches of dural arteries to dural veins or venous sinuses. They are most frequently located at the transverse sinus and cavernous sinus. They can occur at every cranial dural sinus. Dural AV fistula of falx cerebri is rare. A 62-year-old female presented with signs and symptoms of raised intracranial pressure. Radiological imaging revealed a dural AV fistula at the posterior one-third falx cerebri. She underwent transarterial embolization, and complete obliteration of the fistula was achieved. A detailed digital subtraction angiography study is warranted in patients with seemingly benign complaints like recurrent headaches, and falcine dural AV fistula should be identified and treated in the nick of time. We describe a very rare falcine dural AV fistula case and its management.

头颅硬膜动静脉(AV)瘘是硬膜动脉分支与硬膜静脉或静脉窦之间的异常连接。它们最常见于横窦和海绵窦。它们也可能发生在每个头颅硬膜窦。大脑镰硬膜动静脉瘘非常罕见。一名 62 岁的女性出现了颅内压升高的症状和体征。放射成像显示,大脑镰后三分之一处有硬膜外房室瘘。她接受了经动脉栓塞治疗,瘘管被完全堵塞。对于反复头痛等看似良性主诉的患者,有必要进行详细的数字减影血管造影检查,并在关键时刻发现并治疗镰状硬脑膜房室瘘。我们描述了一例非常罕见的镰状硬膜外房室瘘病例及其治疗方法。
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引用次数: 0
Dual Microscope Indocyanine Green Video Angiography and Endoscopic Review to Treat Intracranial Aneurysm: A Review of the Literature Regarding a Case. 治疗颅内动脉瘤的双显微镜吲哚青绿视频血管造影和内窥镜检查:病例文献综述。
Pub Date : 2023-11-30 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1775584
Daniel Alejandro Vega-Moreno, Dragan Janković, Heba Azouz, Mayank Nakipuria, Yoko Kato

The use of the indocyanine green video angiography (ICG-VA) both endoscope and microscope has become popular in recent decades thanks to the safety, efficacy, and added value that they have provided for cerebrovascular surgery. The dual use of these technologies is considered complementary and has helped cerebrovascular surgeons in decision-making, especially for aneurysm clipping surgery; however, its use has been described for both aneurysm surgery, resection of arteriovenous malformations, or even for bypass surgeries. We conducted a review of the literature with the MeSH terms "microscope indocyanine green video angiography (mICG-VA)," "endoscopic review," AND/OR "intracranial aneurysm." A total of 97 articles that included these terms were selected after a primary review to select a total of 26 articles for the final review. We also present a case to exemplify its use, in which we use both technological tools for the description of the aneurysm, as well as for decision-making at the time of clipping and for reclipping. Both tools, both the use of the endoscope and the mICG-VA, have helped decision-making in neurovascular surgery. A considerable clip replacement rate has been described with the use of these technologies, which has helped to reduce the complications associated with poor clipping. One of the main advantages of their usefulness is that they are tools for intraoperative use, which is why they have shown superiority compared to digital subtraction angiography, which takes longer to use and has a higher risk of complications associated with the contrast medium. On the other hand, a very low rate of complications has been described with the use of the endoscope and mICG-VA, which is why they are considered safe tools to use. In some cases, mention has been made of the use of one or the other technology; however, we consider that its dual use provides more information about the status of the clip, its anatomy, its relationship with other vascular structures, and the complete occlusion of the aneurysm. We consider that the use of both technologies is complementary, so in case of having them both should be used, since both the endoscope and the mICG-VA provide additional and useful information.

近几十年来,吲哚菁绿视频血管造影(ICG-VA)内窥镜和显微镜的使用越来越普及,这得益于它们为脑血管手术提供的安全性、有效性和附加值。这些技术的双重使用被认为是互补的,有助于脑血管外科医生做出决策,尤其是动脉瘤夹闭手术;然而,也有文献描述其同时用于动脉瘤手术、动静脉畸形切除术,甚至用于搭桥手术。我们以 "显微镜吲哚青绿视频血管造影(mICG-VA)"、"内窥镜检查 "和/或 "颅内动脉瘤 "为 MeSH 词进行了文献综述。经过初审,共筛选出 97 篇包含这些术语的文章,最后共筛选出 26 篇文章进行最终审查。我们还介绍了一个病例来说明其使用方法,在该病例中,我们使用了这两种技术工具来描述动脉瘤,并在剪切和重新剪切时做出决策。内窥镜和 mICG-VA 这两种工具都有助于神经血管手术的决策。据描述,使用这些技术后,夹子的更换率相当高,有助于减少因剪切不良而引起的并发症。与数字减影血管造影术相比,数字减影血管造影术需要更长的使用时间,而且造影剂引起并发症的风险更高。另一方面,内窥镜和 mICG-VA 的并发症发生率很低,因此被认为是安全的工具。在某些病例中,有人提到只使用其中一种技术,但我们认为,同时使用两种技术可以提供更多信息,包括夹子的状态、解剖结构、与其他血管结构的关系以及动脉瘤的完全闭塞情况。我们认为这两种技术的使用是互补的,因此在有条件的情况下应同时使用这两种技术,因为内窥镜和 mICG-VA 都能提供更多有用的信息。
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引用次数: 0
Lingual Abscess after Posterior Fossa Surgery: An Unusual Complication of the Concorde Position. 后窝手术后的舌脓:协和体位的罕见并发症
Pub Date : 2023-11-30 eCollection Date: 2023-12-01 DOI: 10.1055/s-0043-1776299
Debajyoti Datta, Debarshi Chatterjee, Mona Tiwari

Posterior fossa tumors are one of the most common tumors occurring in children. These tumors are often operated in the Concorde or prone position. Venous congestion can occur due to neck flexion during the positioning causing macroglossia. We report a case of a lingual abscess in a child after surgery in the Concorde position. There was no preoperative evidence of any lingual and dental complaints or injury during intubation. We hypothesize that the lingual abscess in the immediate postoperative period was secondary to venous stasis during the positioning for surgery.

后窝肿瘤是儿童最常见的肿瘤之一。这些肿瘤通常采用协和体位或俯卧位手术。俯卧位时颈部屈曲会导致静脉充血,引起巨舌。我们报告了一例在协和体位手术后发生舌侧脓肿的患儿。术前没有任何舌侧和牙齿不适或插管时受伤的证据。我们推测,术后即刻出现的舌侧脓肿是由于手术体位时静脉淤血引起的。
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引用次数: 0
Rete Middle Cerebral Artery Aneurysm: A Case Report and Systematic Review 脑正中动脉瘤1例报告及系统回顾
Pub Date : 2023-11-07 DOI: 10.1055/s-0043-1775732
Joaquim Francisco Cavalcante-Neto, Gabriel de Almeida Monteiro, Ariane Butke Brandt, Giovanna Esmeraldo Paz Soares, Davi Jorge Fontoura Solla, Paulo Roberto Lacerda Leal, Gerardo Cristino-Filho, Keven Ferreira da Ponte
Abstract Background Middle cerebral artery (MCA) anomalies are a rare finding and may be associated with vascular changes, such as intracranial aneurysms. Among them, the rete MCA aneurysm is very rare, with only 22 cases reported to date. Case Description A 50-year-old woman presented with subarachnoid, intraventricular, and intracerebral hemorrhage secondary to a ruptured aneurysm of rete MCA from an anomalous collateral artery of the anterior cerebral artery, treated successfully by microsurgical clipping. She presented a good recovery after a 2-year follow-up. Conclusion A systematic review of rete MCA aneurysms is presented, comparing aneurysms originating from twig-like MCA, with 16 reports, and twig-like networks of an anomalous collateral artery, with 6 reports including ours. Several factors influence the treatment decision-making, though microsurgical clipping is the main procedure. A wider use of coiling is requested for a better comparison of the treatment approaches.
背景:大脑中动脉(MCA)异常是一种罕见的发现,可能与血管改变有关,如颅内动脉瘤。其中,网状MCA动脉瘤非常罕见,迄今仅有22例报道。病例描述一名50岁女性,因大脑前动脉异常侧支动脉瘤破裂而继发蛛网膜下腔、脑室内出血,经显微外科夹持成功治疗。经过2年的随访,患者恢复良好。结论系统回顾了动脉主干动脉瘤,比较了16例源自MCA小枝状动脉瘤和包括我们在内的6例源自异常侧支动脉的小枝状网络。几个因素影响治疗决策,虽然显微手术夹是主要的程序。为了更好地比较治疗方法,需要更广泛地使用卷取。
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引用次数: 0
Positional Relationship between Two Microcatheters according to the Navigation Sequence within the Curved Vessel in Neuroendovascular Procedures 神经血管内手术中两根微导管在弯曲血管内导航序列的位置关系
Pub Date : 2023-11-07 DOI: 10.1055/s-0043-1775586
Tomotaka Ohshima, Shigeru Miyachi
Abstract In neuroendovascular treatment, there are many opportunities to guide multiple catheters into the intracranial blood vessels. We report the relationship between two microcatheters according to the guiding order with experimental in vitro studies. We hypothesize that in a bent blood vessel such as a paraclinoid region of the internal carotid artery, the catheter that was first guided tended to pass through the inside, and the catheter that was guided later tended to pass through the outside. The in vitro verification was performed using a microcatheter and a balloon catheter in a silicone vascular aneurysmal model. As a result, it was found that the two catheters were arranged according to our hypothesis. This finding was also observed during the actual operation of balloon-assisted coil embolization. The positional relationship between the two catheters according to the navigation order is very important, in particular during balloon-assisted coiling and stent-assisted coiling via a jailed microcatheter.
在神经血管内治疗中,有很多机会引导多根导管进入颅内血管。我们报道了两个微导管之间根据引导顺序的关系,并进行了体外实验研究。我们假设,在弯曲的血管中,比如颈内动脉的线旁区,首先引导的导管倾向于穿过内部,然后引导的导管倾向于穿过外部。使用微导管和球囊导管在硅胶血管动脉瘤模型中进行体外验证。结果发现两根导管按照我们的假设排列。在球囊辅助线圈栓塞的实际操作中也观察到这一发现。根据导航顺序,两根导管之间的位置关系非常重要,特别是在球囊辅助卷绕和支架辅助卷绕时。
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引用次数: 0
A Case of Symptomatic Common Carotid Artery Occlusion Treated by a Bridging Bypass Using Short Saphenous Vein Graft 短隐静脉搭桥治疗症状性颈总动脉闭塞1例
Pub Date : 2023-11-07 DOI: 10.1055/s-0043-1775587
Rikiyoshi Yamamoto, Tomohiro Iida, Naoki Oka, Jouji Kokuzawa, Yasuhiko Kaku
Abstract An 86-year-old woman with initially asymptomatic severe right common carotid artery stenosis had frequent transient left hemiparesis 2 years after the initial diagnosis. Magnetic resonance angiography and three-dimensional computed tomography angiography demonstrated short-segment occlusion of the right carotid bifurcation with significant circumferential calcification, while magnetic resonance imaging demonstrated no ischemic lesions. No collateral blood flow through the anterior communicating artery and posterior communicating artery was observed. A bridging bypass from the distal common carotid artery to the proximal cervical internal carotid artery using a saphenous vein graft was made. There were no ischemic symptoms following the procedure. Bridging bypass using the short saphenous vein graft might be useful for short-segment common carotid artery occlusion.
摘要一名86岁女性,最初无症状的严重右侧颈总动脉狭窄,在初次诊断后2年出现频繁的短暂性左侧偏瘫。磁共振血管造影和三维计算机断层血管造影显示右侧颈动脉分叉短段闭塞伴明显的周向钙化,而磁共振成像显示未见缺血性病变。前交通动脉和后交通动脉未见侧支血流。使用隐静脉移植物从颈总动脉远端到颈内动脉近端进行桥接搭桥。手术后无缺血性症状。短隐静脉移植物桥接旁路可能对短段颈总动脉闭塞有用。
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引用次数: 0
Propofol versus Desflurane in Moyamoya Disease Patients—A Pilot Study 异丙酚与地氟醚在烟雾病患者中的对照研究
Pub Date : 2023-11-07 DOI: 10.1055/s-0043-1775588
Ronak R. Ankolekar, Kirandeep Kaur, Kiran Jangra, Ashish Aggarwal, Nidhi B. Panda, Hemant Bhagat, Amiya K. Barik
Abstract Objectives The choice of inhalational or intravenous anesthetic agents is debatable in neurosurgical patients. Desflurane, a cerebral vasodilator, may be advantageous in ischemic cerebral pathologies. Hence, we planned to compare desflurane and propofol in patients with moyamoya disease (MMD) with the objective of comparing neurological outcomes. Materials and Methods This prospective pilot trial was initiated after institutional ethics committee approval. Patients with MMD undergoing revascularization surgery were randomized into two groups receiving either desflurane or propofol intraoperatively. Neurological outcomes were assessed using a modified Rankin score (mRS) at discharge and an extended Glasgow outcome score (GOS-E) at 1 month. Intraoperative parameters, including hemodynamic parameters, end-tidal carbon dioxide, entropy, intraoperative brain relaxation scores (BRS), and rescue measures for brain relaxation, were compared. Statistical Analysis The normality of quantitative data was checked using Kolmogorov–Smirnov tests of normality. Normally distributed data were compared using unpaired t-tests, skewed data using Mann–Whitney U tests, and categorical variables using chi-squared tests. Results A total of 17 patients were randomized, 10 in the desflurane and 7 in the propofol group. mRS (1.3 ± 0.6 and 1.14 ± 0.4, p = 0.450) and GOS-E (6.7 ± 0.6 and 6.85 ± 0.5, p = 0.45) were comparable between desflurane and propofol groups, respectively. BRS was significantly higher in the desflurane group (3.6 ± 0.5) compared to the propofol group (2.1 ± 0.3, p = 0.001), with a significant number of patients requiring rescue measures in the desflurane group (70%, p < 0.001). Other outcome parameters were comparable (p > 0.05). Conclusion We conclude that postoperative neurological outcomes were comparable with using either an anesthetic agent, desflurane, or propofol in MMD patients undergoing revascularization surgery. Maintenance of anesthesia with propofol had significantly superior surgical field conditions.
摘要目的神经外科患者是选择吸入麻醉还是静脉麻醉是有争议的。地氟醚是一种脑血管扩张剂,可能有利于缺血性脑病。因此,我们计划比较地氟醚和异丙酚在烟雾病(MMD)患者中的作用,目的是比较神经系统预后。材料与方法本前瞻性先导试验经机构伦理委员会批准启动。接受血管重建手术的烟雾病患者被随机分为两组,术中使用地氟醚或异丙酚。出院时使用改良Rankin评分(mRS)和1个月时使用扩展格拉斯哥评分(GOS-E)评估神经学预后。比较术中参数,包括血流动力学参数、潮末二氧化碳、熵、术中脑松弛评分(BRS)和脑松弛抢救措施。统计分析采用Kolmogorov-Smirnov正态性检验定量数据的正态性。正态分布数据采用非配对t检验,偏态数据采用Mann-Whitney U检验,分类变量采用卡方检验。结果随机抽取17例患者,地氟醚组10例,异丙酚组7例。地氟醚组和异丙酚组的mRS(1.3±0.6和1.14±0.4,p = 0.450)和GOS-E(6.7±0.6和6.85±0.5,p = 0.45)具有可比性。地氟醚组BRS(3.6±0.5)显著高于异丙酚组(2.1±0.3,p = 0.001),且地氟醚组需要采取抢救措施的患者数量显著(70%,p <0.001)。其他结局参数具有可比性(p >0.05)。结论:我们的结论是,在接受血管重建手术的烟雾病患者中,术后神经系统预后与使用麻醉剂地氟醚或异丙酚相当。异丙酚维持麻醉有明显优越的手术野条件。
{"title":"Propofol versus Desflurane in Moyamoya Disease Patients—A Pilot Study","authors":"Ronak R. Ankolekar, Kirandeep Kaur, Kiran Jangra, Ashish Aggarwal, Nidhi B. Panda, Hemant Bhagat, Amiya K. Barik","doi":"10.1055/s-0043-1775588","DOIUrl":"https://doi.org/10.1055/s-0043-1775588","url":null,"abstract":"Abstract Objectives The choice of inhalational or intravenous anesthetic agents is debatable in neurosurgical patients. Desflurane, a cerebral vasodilator, may be advantageous in ischemic cerebral pathologies. Hence, we planned to compare desflurane and propofol in patients with moyamoya disease (MMD) with the objective of comparing neurological outcomes. Materials and Methods This prospective pilot trial was initiated after institutional ethics committee approval. Patients with MMD undergoing revascularization surgery were randomized into two groups receiving either desflurane or propofol intraoperatively. Neurological outcomes were assessed using a modified Rankin score (mRS) at discharge and an extended Glasgow outcome score (GOS-E) at 1 month. Intraoperative parameters, including hemodynamic parameters, end-tidal carbon dioxide, entropy, intraoperative brain relaxation scores (BRS), and rescue measures for brain relaxation, were compared. Statistical Analysis The normality of quantitative data was checked using Kolmogorov–Smirnov tests of normality. Normally distributed data were compared using unpaired t-tests, skewed data using Mann–Whitney U tests, and categorical variables using chi-squared tests. Results A total of 17 patients were randomized, 10 in the desflurane and 7 in the propofol group. mRS (1.3 ± 0.6 and 1.14 ± 0.4, p = 0.450) and GOS-E (6.7 ± 0.6 and 6.85 ± 0.5, p = 0.45) were comparable between desflurane and propofol groups, respectively. BRS was significantly higher in the desflurane group (3.6 ± 0.5) compared to the propofol group (2.1 ± 0.3, p = 0.001), with a significant number of patients requiring rescue measures in the desflurane group (70%, p < 0.001). Other outcome parameters were comparable (p > 0.05). Conclusion We conclude that postoperative neurological outcomes were comparable with using either an anesthetic agent, desflurane, or propofol in MMD patients undergoing revascularization surgery. Maintenance of anesthesia with propofol had significantly superior surgical field conditions.","PeriodicalId":94300,"journal":{"name":"Asian journal of neurosurgery","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135539914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Intracranial Cavernous Malformation with Concomitant Isolated Cerebral Mucormycosis Infection: A Case Report 颅内海绵体畸形伴孤立性脑毛霉菌病感染1例
Pub Date : 2023-11-07 DOI: 10.1055/s-0043-1772765
Pratishtha Sengar, Nityanand Pandey, Vikas Kailashiya, Varun Kumar Singh
Abstract Cerebral cavernous malformation is an angiographically occult, well-circumscribed, benign hamartoma consisting of thin-walled sinusoidal vascular channels. Intracranial mucormycosis represents one of the most severe manifestations of mucor infection. We, hereby, report a case of cavernous malformation made rarer with concomitant mucormycosis. A 22-year-old female presented with left-sided facial seizures since age of 7 years and headache for the past 3 years. Magnetic resonance imaging brain revealed a right posterior frontal lobe cavernous malformation. Right frontal craniotomy with excision of cavernoma was done. Gross examination showed a solid cystic mass with multiple mulberry protrusions. Histopathological examination revealed features of cavernous malformation with evidence of mucormycosis. A final diagnosis of cavernous malformation with mucormycosis was rendered and microbiological studies were advised. To the best of our knowledge, this is the first case report of a cerebral cavernous malformation with mucormycosis in an immunocompetent patient without any risk factor.
摘要:脑海绵状血管瘤是一种由薄壁正弦血管通道组成的血管造影隐匿、边界明确的良性错构瘤。颅内毛霉病是毛霉感染最严重的表现之一。在此,我们报告一例海绵体畸形与伴随毛霉菌病的罕见病例。22岁女性,7岁以来左侧面部癫痫发作,过去3年头痛。脑磁共振成像显示右侧额叶后海绵状畸形。右额叶开颅切除海绵状瘤。大体检查显示实性囊性肿块伴多发桑葚突。组织病理学检查显示海绵状畸形的特征,并有毛霉病的证据。最终诊断为海绵状畸形伴毛霉菌病,并建议进行微生物学检查。据我们所知,这是第一例无任何危险因素的免疫功能正常的脑海绵体畸形伴毛霉菌病的病例报告。
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引用次数: 0
Comparison of Cardiac Indices Using Two Different Concentrations of Topical Adrenaline during Endoscopic Transsphenoidal Pituitary Surgery: A Prospective Randomized Observational Study 内镜下经蝶窦垂体手术中使用两种不同浓度肾上腺素对心脏指标的比较:一项前瞻性随机观察研究
Pub Date : 2023-11-07 DOI: 10.1055/s-0043-1775585
Archana Gautam, Rudrashish Haldar, Shashi Srivastava, Devendra Gupta, Awadhesh Kumar Jaiswal, Prabhaker Mishra
Abstract Introduction Adrenaline-soaked wicks are often employed to decongest nasal mucosa during transsphenoidal pituitary surgeries to ensure proper hemostasis and visibility of the operating field. Considerable debate exists regarding the optimum concentration of adrenaline that strikes a balance between hemostasis as well as the hemodynamic side effects of adrenaline. This study assessed cardiac indices like cardiac output and cardiac index using a FloTrac Vigileo cardiac output monitor to compare two different concentrations of adrenaline used for topical instillation. Methods and Materials 60 adult patients undergoing transsphenoidal pituitary surgery were randomly assigned to receive cotton wicks soaked in adrenaline solution (either 1:100,000 or 1:200,000) for nasal decongestion. Following a standardized anesthetic regime, a FloTrac Vigileo cardiac output monitor was attached with the invasive arterial line for precise monitoring and recording of cardiac indices (cardiac output and cardiac index). Additionally, quality of surgical field (as reported by the operating surgeon) blood loss, incidences of adverse hemodynamic events, and rescue drug usage were recorded. Results No difference in cardiac outputs and cardiac indexes of the patients was observed during baseline to 55 minutes and at 80 minutes and onward, whereas difference rose to statistical significance at the time points of 60 minutes and 70 minutes (p < 0.05). Other parameters like stroke volume, stroke volume variation, and hemodynamic parameters were similar. Quality of the surgical fields (as reported by the surgeon), intraoperative bleeding, incidences of adverse effects, and frequency of rescue drugs usage were similar. Conclusion Instillation of 1:100,000 dilution of adrenaline solution compared with 1:200,000 for nasal decongestion is associated with significant rise in cardiac output and cardiac index at 60 and 70 minutes of the surgery with similar blood loss and hemodynamic variables. Therefore, the lower concentration of adrenaline can be recommended for usage during transsphenoidal pituitary surgeries.
在经蝶窦垂体手术中,肾上腺素浸泡芯常用于减少鼻黏膜充血,以确保适当的止血和术野的可见度。关于肾上腺素在止血和肾上腺素血流动力学副作用之间达到平衡的最佳浓度,存在着相当大的争论。本研究使用FloTrac Vigileo心输出量监测仪评估心输出量和心脏指数等心脏指标,比较两种不同浓度的肾上腺素用于局部注射。方法与材料选择60例经蝶窦垂体手术的成人患者,随机给予肾上腺素溶液(1:10万或1:20万)浸棉芯缓解鼻充血。在标准化麻醉方案后,将FloTrac Vigileo心输出量监测仪与有创动脉线连接,以精确监测和记录心脏指数(心输出量和心脏指数)。此外,记录手术野质量(由手术医生报告)、失血量、不良血流动力学事件发生率和抢救用药情况。结果两组患者的心输出量和心脏指数在基线至55分钟和80分钟及以后无差异,而在60分钟和70分钟时差异有统计学意义(p <0.05)。其他参数如卒中量、卒中量变化和血流动力学参数相似。手术野的质量(由外科医生报告)、术中出血、不良反应的发生率和抢救药物的使用频率相似。结论与1:20万稀释肾上腺素溶液相比,1:10万稀释肾上腺素溶液在手术后60、70分钟的心排血量和心脏指数明显升高,出血量和血流动力学指标相似。因此,建议在经蝶窦垂体手术时使用较低浓度的肾上腺素。
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引用次数: 0
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Asian journal of neurosurgery
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