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Strategies to guide the successful implementation of deprescribing in community practice: Lessons learned from the front line 指导在社区实践中成功实施去处方化的策略:从第一线汲取的经验教训
Pub Date : 2024-04-13 DOI: 10.1177/17151635241240737
Justin P. Turner, Kelda Newport, Aisling M. McEvoy, Tara Smith, Cara Tannenbaum, Deborah V. Kelly
Sustainable implementation of new professional services into clinical practice can be difficult. In 2019, a population-wide initiative called SaferMedsNL was implemented across the province of Newfoundland and Labrador (NL), to promote appropriate medication use. Two evidence-based interventions were adapted to the context of NL to promote deprescribing of proton pump inhibitors and sedatives. The objective of this study was to identify and prioritize which actions supported the implementation of deprescribing in community practice for pharmacists, physicians and nurse practitioners across the province. Community pharmacists, physicians and nurse practitioners were invited to participate in virtual focus groups. Nominal Group Technique was used to elicit responses to the question: “What actions support the implementation of deprescribing into the daily workflow of your practice?” Participants prioritized actions within each group while thematic analysis permitted comparison across groups. Five focus groups were held in fall 2020 involving pharmacists ( n = 11), physicians ( n = 7) and nurse practitioners ( n = 4). Participants worked in rural ( n = 10) and urban ( n = 12) settings. The different groups agreed on what the top 5 actions were, with the top 5 receiving 68% of the scores: (1) providing patient education, (2) allocating time and resources, (3) building interprofessional collaboration and communication, (4) fostering patient relationships and (5) aligning with public awareness strategies. Pharmacists, physicians and nurse practitioners identified similar actions that supported implementing evidence-based deprescribing into routine clinical practice. Sharing these strategies may help others embed deprescribing into daily practice and assist the uptake of medication appropriateness initiatives by front-line providers. Can Pharm J (Ott) 2024;157:xx-xx.
在临床实践中可持续地实施新的专业服务可能很困难。2019 年,纽芬兰省和拉布拉多省(NL)在全省范围内实施了一项名为 "SaferMedsNL "的全民倡议,以促进合理用药。根据纽芬兰省的实际情况,对两项循证干预措施进行了调整,以促进质子泵抑制剂和镇静剂的停药。这项研究的目的是确定并优先考虑哪些行动支持全省的药剂师、医生和执业护士在社区实践中实施去处方化。社区药剂师、医生和执业护士应邀参加了虚拟焦点小组。我们采用了名义小组技术来征求对问题的回答:"哪些行动支持在您的日常工作流程中实施去处方化?参与者对每个小组内的行动进行了优先排序,同时通过主题分析对各小组进行了比较。2020 年秋季举行了五次焦点小组讨论,参与人员包括药剂师(11 人)、医生(7 人)和执业护士(4 人)。参与者分别在农村(10 人)和城市(12 人)工作。不同小组就前 5 项行动达成了一致,前 5 项行动获得了 68% 的评分:(1) 提供患者教育,(2) 分配时间和资源,(3) 建立专业间合作与沟通,(4) 促进患者关系,(5) 与公众意识战略保持一致。药剂师、医生和执业护士也提出了类似的行动,以支持在常规临床实践中实施循证处方。分享这些策略可以帮助其他人将去势处方纳入日常实践,并帮助一线医疗人员采纳用药适宜性倡议。Can Pharm J (Ott) 2024;157:xx-xx.
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引用次数: 0
Influenza vaccination in community pharmacy: A cross-sectional survey of Canadian adults’ knowledge, attitude and beliefs 社区药房的流感疫苗接种:加拿大成年人的知识、态度和信念横断面调查
Pub Date : 2024-04-11 DOI: 10.1177/17151635241240464
S. Houle, Ajit Johal, Paul Roumeliotis, Bertrand Roy, Wendy Boivin
In Canada, influenza vaccination rates are below recommended targets, with pharmacies the leading setting for vaccine administration. This work aimed to determine the Canadian public’s current knowledge, attitudes and practices related to pharmacy-based influenza vaccination services. We surveyed 3000 Canadian residents aged ≥18 years using a cross-sectional, self-reported, online structured questionnaire between December 5 and 21, 2022. A representative survey population was recruited from the Léger Opinion (LEO) consumer panel. Data were weighted by age, region and gender, based on 2021 census data. During the 2022–2023 season, 56.6% (95% confidence interval [CI], 54%-59.2%) of respondents reported receiving an influenza vaccine at a pharmacy, including 57.5% (95% CI, 54.2%-60.8%) of respondents considered to be at high risk of complications from influenza. Among respondents previously vaccinated at a pharmacy, 94.1% (95% CI, 91%-97.2%) were satisfied with the experience, citing convenience, accessibility and availability as factors influencing their decision. Among all respondents, 29.3% (95% CI, 27.5%-31.1%) reported that a pharmacist’s recommendation for the influenza vaccine would affect their decision to be vaccinated, yet only 10.4% (95% CI, 5.9%-15%) who had discussions with a pharmacist specifically discussed the importance of influenza vaccination. Canadians are satisfied with pharmacy-based influenza vaccinations and value pharmacist recommendations. Pharmacists have an opportunity to boost influenza vaccination coverage in Canada by providing counselling on the importance of influenza vaccination to those seeking their advice on other health care needs, including younger adults and those with risk factors for serious illness from influenza.
在加拿大,流感疫苗接种率低于建议目标,而药房是疫苗接种的主要场所。这项工作旨在了解加拿大公众目前对药房流感疫苗接种服务的认识、态度和做法。我们在 2022 年 12 月 5 日至 21 日期间使用横断面、自我报告、在线结构化问卷调查了 3000 名年龄≥18 岁的加拿大居民。我们从 Léger Opinion (LEO) 消费者小组中招募了具有代表性的调查人群。根据 2021 年人口普查数据,按年龄、地区和性别对数据进行了加权处理。在2022-2023年流感季节,56.6%(95%置信区间[CI],54%-59.2%)的受访者表示曾在药店接种过流感疫苗,其中包括57.5%(95%置信区间[CI],54.2%-60.8%)被认为是流感并发症高危人群的受访者。在曾经在药房接种过疫苗的受访者中,94.1%(95% CI,91%-97.2%)的受访者对接种经历表示满意,认为方便、容易获得和可用性是影响他们做出接种决定的因素。在所有受访者中,29.3%(95% CI,27.5%-31.1%)表示药剂师对流感疫苗的推荐会影响他们接种疫苗的决定,但只有 10.4%(95% CI,5.9%-15%)与药剂师讨论过流感疫苗接种的重要性。加拿大人对在药房接种流感疫苗感到满意,并重视药剂师的建议。药剂师有机会提高加拿大的流感疫苗接种覆盖率,方法是向那些就其他医疗保健需求寻求药剂师建议的人提供有关流感疫苗接种重要性的咨询,其中包括年轻人和有流感重症风险因素的人。
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引用次数: 1
“Are you sure you want to be a pharmacist?” "你确定要当药剂师吗?"
Pub Date : 2024-04-11 DOI: 10.1177/17151635241241044
Kevin Ta
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引用次数: 0
Developing pharmacy leaders: A design thinking approach to navigate the leadership crisis in pharmacy 培养药学领导者:以设计思维方法应对药学领导力危机
Pub Date : 2024-04-09 DOI: 10.1177/17151635241240470
Kayla Byers, Angela Gee, M. Anwar
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引用次数: 0
Do we need to separate pharmacy advocacy organizations? 我们需要将药房宣传组织分开吗?
Pub Date : 2024-04-09 DOI: 10.1177/17151635241241039
Shania Liu, Ross T. Tsuyuki
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引用次数: 0
Health human resources planning in Canada—Part II: Its importance for pharmacy in Canada 加拿大卫生人力资源规划--第二部分:其对加拿大药房的重要性
Pub Date : 2024-03-28 DOI: 10.1177/17151635241239884
Natalie Crown, I. Bourgeault, Z. Austin
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引用次数: 0
A new curricular framework for an interprofessional approach to deprescribing: Why and how pharmacists should lead the way 针对取消处方的跨专业方法的新课程框架:药剂师为何以及如何发挥带头作用
Pub Date : 2024-03-15 DOI: 10.1177/17151635241239924
Brenda G. Schuster, Sadaf Faisal, Camille L. Gagnon
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引用次数: 0
Medical assistance in dying: A reflection tool for pharmacists 临终医疗救助:药剂师的思考工具
Pub Date : 2024-02-15 DOI: 10.1177/17151635241228215
J. Navarrete, Margaret Gray, Michelle A. King, Amary Mey, Phillip Woods, Theresa J. Schindel
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引用次数: 0
An economic evaluation of community pharmacy dispensed naloxone in Canada 加拿大社区药房配发纳洛酮的经济评估
Pub Date : 2024-02-13 DOI: 10.1177/17151635241228241
Ashley Cid, Nikita Mahajan, William W.L. Wong, Michael Beazely, K. Grindrod
To determine the cost-effectiveness of pharmacy-based intranasal (IN) and intramuscular (IM) naloxone distribution in Canada. We developed a state-transition model for pharmacy-based naloxone distribution, every 3 years, to illicit, prescription, opioid-agonist therapy and nonopioid use populations compared to no naloxone distribution. We used a monthly cycle length, lifetime horizon and a Canadian provincial Ministry of Health perspective. Transition probabilities, cost and utility data were retrieved from the literature. Costs (2020) and quality-adjusted life years (QALY) were discounted 1.5% annually. Microsimulation, 1-way and probabilistic sensitivity analyses were conducted. Distribution of naloxone to all Canadians compared to no distribution prevented 151 additional overdose deaths per 10,000 persons, with an incremental cost-effectiveness ratio (ICER) of $50,984 per QALY for IM naloxone and an ICER of $126,060 per QALY for IN naloxone. Distribution of any naloxone to only illicit opioid users was the most cost-effective. One-way sensitivity analysis showed that survival rates for illicit opioid users were most influenced by the availability of either emergency medical services or naloxone. Distribution of IM and IN naloxone to all Canadians every 3 years is likely cost-effective at a willingness-to-pay threshold of $140,000 Canadian dollars/QALY (~3 × gross domestic product from the World Health Organization). Distribution to people who use illicit opioids was most cost-effective and prevented the most deaths. This is important, as more overdose deaths could be prevented through nationwide public funding of IN naloxone kits through pharmacies, since individuals report a preference for IN naloxone and these formulations are easier to use, save lives and are cost-effective. Can Pharm J (Ott) 2024;157:xx-xx.
目的是确定在加拿大通过药房分发鼻内(IN)和肌肉注射(IM)纳洛酮的成本效益。与不分发纳洛酮相比,我们建立了一个州过渡模型,用于每 3 年向非法、处方、阿片激动剂治疗和非阿片类药物使用人群分发纳洛酮。我们采用了月度周期长度、终生范围和加拿大省级卫生部的观点。过渡概率、成本和效用数据均来自文献。成本(2020 年)和质量调整生命年(QALY)的年贴现率为 1.5%。进行了微观模拟、单向和概率敏感性分析。与不发放纳洛酮相比,向所有加拿大人发放纳洛酮可防止每 10,000 人中增加 151 例吸毒过量死亡,IM 纳洛酮的增量成本效益比 (ICER) 为每 QALY 50,984 美元,IN 纳洛酮的 ICER 为每 QALY 126,060 美元。仅向非法阿片类药物使用者分发纳洛酮最具成本效益。单向敏感性分析表明,非法阿片类药物使用者的存活率受紧急医疗服务或纳洛酮供应情况的影响最大。每 3 年向所有加拿大人分发一次纳洛酮(IM 和 IN)可能具有成本效益,支付意愿阈值为 140,000 加元/QALY(约为世界卫生组织国内生产总值的 3 倍)。向使用非法阿片类药物的人分发药物最具成本效益,也能防止最多的死亡。这一点非常重要,因为通过药店在全国范围内公共资助 IN 纳洛酮试剂盒,可以预防更多的用药过量死亡,因为据个人报告,他们更喜欢 IN 纳洛酮,而且这些制剂更易于使用,可以挽救生命,成本效益也更高。Can Pharm J (Ott) 2024;157:xx-xx.
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引用次数: 0
An economic evaluation of community pharmacy dispensed naloxone in Canada 加拿大社区药房配发纳洛酮的经济评估
Pub Date : 2024-02-13 DOI: 10.1177/17151635241228241
Ashley Cid, Nikita Mahajan, William W.L. Wong, Michael Beazely, K. Grindrod
To determine the cost-effectiveness of pharmacy-based intranasal (IN) and intramuscular (IM) naloxone distribution in Canada. We developed a state-transition model for pharmacy-based naloxone distribution, every 3 years, to illicit, prescription, opioid-agonist therapy and nonopioid use populations compared to no naloxone distribution. We used a monthly cycle length, lifetime horizon and a Canadian provincial Ministry of Health perspective. Transition probabilities, cost and utility data were retrieved from the literature. Costs (2020) and quality-adjusted life years (QALY) were discounted 1.5% annually. Microsimulation, 1-way and probabilistic sensitivity analyses were conducted. Distribution of naloxone to all Canadians compared to no distribution prevented 151 additional overdose deaths per 10,000 persons, with an incremental cost-effectiveness ratio (ICER) of $50,984 per QALY for IM naloxone and an ICER of $126,060 per QALY for IN naloxone. Distribution of any naloxone to only illicit opioid users was the most cost-effective. One-way sensitivity analysis showed that survival rates for illicit opioid users were most influenced by the availability of either emergency medical services or naloxone. Distribution of IM and IN naloxone to all Canadians every 3 years is likely cost-effective at a willingness-to-pay threshold of $140,000 Canadian dollars/QALY (~3 × gross domestic product from the World Health Organization). Distribution to people who use illicit opioids was most cost-effective and prevented the most deaths. This is important, as more overdose deaths could be prevented through nationwide public funding of IN naloxone kits through pharmacies, since individuals report a preference for IN naloxone and these formulations are easier to use, save lives and are cost-effective. Can Pharm J (Ott) 2024;157:xx-xx.
目的是确定在加拿大通过药房分发鼻内(IN)和肌肉注射(IM)纳洛酮的成本效益。与不分发纳洛酮相比,我们建立了一个州过渡模型,用于每 3 年向非法、处方、阿片激动剂治疗和非阿片类药物使用人群分发纳洛酮。我们采用了月度周期长度、终生范围和加拿大省级卫生部的观点。过渡概率、成本和效用数据均来自文献。成本(2020 年)和质量调整生命年(QALY)的年贴现率为 1.5%。进行了微观模拟、单向和概率敏感性分析。与不发放纳洛酮相比,向所有加拿大人发放纳洛酮可防止每 10,000 人中增加 151 例吸毒过量死亡,IM 纳洛酮的增量成本效益比 (ICER) 为每 QALY 50,984 美元,IN 纳洛酮的 ICER 为每 QALY 126,060 美元。仅向非法阿片类药物使用者分发纳洛酮最具成本效益。单向敏感性分析表明,非法阿片类药物使用者的存活率受紧急医疗服务或纳洛酮供应情况的影响最大。每 3 年向所有加拿大人分发一次纳洛酮(IM 和 IN)可能具有成本效益,支付意愿阈值为 140,000 加元/QALY(约为世界卫生组织国内生产总值的 3 倍)。向使用非法阿片类药物的人分发药物最具成本效益,也能防止最多的死亡。这一点非常重要,因为通过药店在全国范围内公共资助 IN 纳洛酮试剂盒,可以预防更多的用药过量死亡,因为据个人报告,他们更喜欢 IN 纳洛酮,而且这些制剂更易于使用,可以挽救生命,成本效益也更高。Can Pharm J (Ott) 2024;157:xx-xx.
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Canadian Pharmacists Journal / Revue des Pharmaciens du Canada
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