Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4405
S. Chelvanambi, N. Bogatcheva, P. Jolicoeur, H. Twigg, M. Clauss
{"title":"HIV-Nef Protein Persists in Bronchoalveolar Lavage Derived Extracellular Vesicles of HIV Patients on ART and Induces EMAPII Amplified Endothelial Cell Apoptosis Resulting in Pulmonary Vascular Pathologies Like Pulmonary Hypertension","authors":"S. Chelvanambi, N. Bogatcheva, P. Jolicoeur, H. Twigg, M. Clauss","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4405","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4405","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"46 9 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80506592","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4397
J. Karnes, T. Thayer, Amit Arora, Ken Batai, S. Halladay, K. Lutz, A. Coleman, M. Pauciulo, Richard Kittles, J. G. Garcia, J. Yuan, M. Geraci, James West, A. Hemnes, R. Stearman, W. Nichols, E. Brittain, A. Desai
{"title":"Sorting Nexin 29 (SNX29) as a Novel Biomarker for Vasoresponsive Pulmonary Arterial Hypertension","authors":"J. Karnes, T. Thayer, Amit Arora, Ken Batai, S. Halladay, K. Lutz, A. Coleman, M. Pauciulo, Richard Kittles, J. G. Garcia, J. Yuan, M. Geraci, James West, A. Hemnes, R. Stearman, W. Nichols, E. Brittain, A. Desai","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4397","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4397","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"59 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90614974","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4403
K. Prins, E. Brittain, T. Assad, R. Kalra, Lauren Rose, S. Archer, E. Weir, M. Pritzker, T. Thenappan
{"title":"Serum Chloride Is a Prognostic Marker in Pulmonary Arterial Hypertension","authors":"K. Prins, E. Brittain, T. Assad, R. Kalra, Lauren Rose, S. Archer, E. Weir, M. Pritzker, T. Thenappan","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4403","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4403","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"7 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90249777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4391
Corina Marziano, Kwang-Shik Hong, Eric L. Cope, Matteo Ottolini, Swapnil K. Sonkusare
{"title":"Impairment of Endothelial Caveolin-1-TRPV4 Channel Signaling in Pulmonary Hypertension","authors":"Corina Marziano, Kwang-Shik Hong, Eric L. Cope, Matteo Ottolini, Swapnil K. Sonkusare","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4391","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4391","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"90 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"83908798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4411
M. Talati, Xinping Chen, S. Shay, S. Gladson, J. Penn, James West
{"title":"Msx1 Overexpression in Mouse Lung Leads to Loss of Small Pulmonary Vessels","authors":"M. Talati, Xinping Chen, S. Shay, S. Gladson, J. Penn, James West","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4411","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4411","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"2010 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73854449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4406
A. Alobaida, F. Ahsan
{"title":"Inhaled PLGA Particles of Spermine Nonoate, Nitric Oxide Donor, as a Promising Targeted Therapy to Reduce Pulmonary Arterial Pressure in PAH","authors":"A. Alobaida, F. Ahsan","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4406","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4406","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"68 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87508375","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4396
C. Simpson, R. Damico, P. Hassoun, Jun Yang, Melanie K Nies, M. Griffiths, Dhananjay Vaidya, Stephanie Brandal, M. Pauciulo, E. Austin, D. Ivy, W. Nichols, A. Everett
{"title":"Circulating Serum ST2 as a Biomarker of Disease Severity and Survival in Pulmonary Arterial Hypertension","authors":"C. Simpson, R. Damico, P. Hassoun, Jun Yang, Melanie K Nies, M. Griffiths, Dhananjay Vaidya, Stephanie Brandal, M. Pauciulo, E. Austin, D. Ivy, W. Nichols, A. Everett","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4396","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4396","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"3 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89350782","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4409
M. Simon, M. Gomberg-Maitland, R. Oudiz, R. Machado, F. Rischard, J. Elinoff, B. Grigorian, A. Schmid, S. Hou, N. Desai, M. Gladwin
{"title":"ABI-009, nab-Sirolimus, an mTOR Inhibitor with High Lung Accumulation in Preclinical Models Is Active in Patients with Severe Pulmonary Arterial Hypertension","authors":"M. Simon, M. Gomberg-Maitland, R. Oudiz, R. Machado, F. Rischard, J. Elinoff, B. Grigorian, A. Schmid, S. Hou, N. Desai, M. Gladwin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4409","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4409","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"13 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"84354972","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4399
T. Koudstaal, J. V. Hulst, P. Heukels, D. Merkus, M. Raaf, I. Bergen, H. Bogaard, L. Boon, G. Loo, J. Aerts, Rudolf W. Hendriks, K. Boomars, M. Kool
{"title":"Anti-IL-6 Treatment Ameliorates the Pulmonary Hypertension Phenotype in Tnfaip3DNGR1-KOMice","authors":"T. Koudstaal, J. V. Hulst, P. Heukels, D. Merkus, M. Raaf, I. Bergen, H. Bogaard, L. Boon, G. Loo, J. Aerts, Rudolf W. Hendriks, K. Boomars, M. Kool","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4399","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4399","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"31 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82850880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4398
S. Singla, Z. Zeng, Weiguo Chen, R. Demeritte, Jiwang Chen, J. Jacobson, S. Dudek, V. Natarajan, R. Machado
{"title":"Endothelial-Specific Knockdown of Lung WWOX Expression Worsens Acute Lung Injury","authors":"S. Singla, Z. Zeng, Weiguo Chen, R. Demeritte, Jiwang Chen, J. Jacobson, S. Dudek, V. Natarajan, R. Machado","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4398","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4398","url":null,"abstract":"","PeriodicalId":9568,"journal":{"name":"C26. LET IT BLEED: ENDOTHELIAL INJURY AND ANGIOGENESIS IN PULMONARY HYPERTENSION","volume":"67 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"73757721","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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