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Posttraumatic Pancreatitis Four Days after Renal Injury with Massive Retroperitoneal Hematoma. 创伤后胰腺炎肾损伤后四天,腹膜后大量血肿。
Pub Date : 2021-05-07 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6693259
Masamichi Kiriyama, Kei Jitsuiki, Ken-Ichi Muramatsu, Hoshiko Furusawa, Soshi Moriya, Youichi Yanagawa

A 25-year-old man accidentally fell from a cliff and hit his right flank on the ground while camping. Initially, he was able to barely walk, but he ultimately became unable to walk at all due to severe flank pain. He had no remarkable personal or family history and was a social drinker. Upon arrival, he showed clear consciousness but was in a hemorrhagic shock state. Enhanced computed tomography (CT) revealed extravasation of contrast medium from the injured right kidney with massive retroperitoneal hematoma. He underwent massive blood transfusion and tracheal intubation followed by renal embolization. His vital signs stabilized on hospital day 2, and he was extubated on day 3. On days 4 and 5, a blood examination revealed increased levels of amylase (360 and 904 IU/L, respectively). Enhanced CT on day 5 did not show signs of severe acute pancreatitis. The maximum amylase level was 1041 IU/L on day 6 and decreased day by day without deterioration of the severity of his acute pancreatitis. He was discharged on day 14. The subacute phase of posttraumatic acute pancreatitis in the present case may have been induced not by direct injury to the pancreas but by several causative factors, such as shock, increased pressure of the retroperitoneal space, or the release of inflammatory mediators from injured tissues or hematoma.

一名25岁的男子在露营时不小心从悬崖上摔下来,击中了右侧的地面。起初,他几乎不能走路,但由于严重的腰痛,他最终完全不能走路。他没有什么特别的个人或家族病史,只是个应酬酒鬼。到达时,他意识清醒,但处于失血性休克状态。增强计算机断层扫描(CT)显示造影剂外溢从受伤的右肾和大量腹膜后血肿。他接受了大量输血和气管插管,随后进行了肾栓塞。住院第2天生命体征稳定,第3天拔管。在第4天和第5天,血液检查显示淀粉酶水平升高(分别为360和904 IU/L)。第5天增强CT未见严重急性胰腺炎征象。第6天淀粉酶水平最高为1041 IU/L,并逐渐下降,急性胰腺炎的严重程度未恶化。他于第14天出院。在本病例中,创伤后急性胰腺炎的亚急性期可能不是由胰腺的直接损伤引起的,而是由几种致病因素引起的,如休克、腹膜后间隙压力增加或损伤组织或血肿释放炎症介质。
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引用次数: 2
Nearly Fatal Hydroxychloroquine Overdose Successfully Treated with Midazolam, Propofol, Sodium Bicarbonate, Norepinephrine, and Intravenous Lipid Emulsion. 咪达唑仑、异丙酚、碳酸氢钠、去甲肾上腺素和静脉脂质乳成功治疗几乎致命的羟氯喹过量。
Pub Date : 2021-04-20 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8876256
Goswin Onsia, Sarah Bots

Background: In the context of the current COVID-19 pandemic, there has been renewed interest in the drug hydroxychloroquine. However, clinicians should be aware of the dangers of hydroxychloroquine intoxication, an insufficiently studied condition. Case Report. We present a case of autointoxication with 20 g hydroxychloroquine in a 35-year-old woman. Cardiac monitoring showed ventricular arrhythmias for which high-dose midazolam and propofol were initiated, resulting in a brief normalization of the cardiac rhythm. Because of the reoccurrence of these arrhythmias, intravenous lipid emulsion was administered with fast cardiac stabilization. Treatment with continuous norepinephrine, potassium chloride/phosphate, and sodium bicarbonate was initiated. On day 6, she was extubated and after 11 days, she was discharged from the hospital without complications.

Conclusion: Since high-quality scientific evidence is lacking, treatment options are based on experience in chloroquine toxicity. Activated charcoal is advised if the patient presents early. Sedation with diazepam, early ventilation, and continuous epinephrine infusion are considered effective in treating severe intoxication. Caution is advised when substituting potassium. Despite the lack of formal evidence, sodium bicarbonate appears to be useful and safe in case of QRS widening. Intravenous lipid emulsion, with or without hemodialysis, remains controversial but appears to be safe. As a last resort, extracorporeal life support might be considered in case of persisting hemodynamic instability.

背景:在当前COVID-19大流行的背景下,人们对羟氯喹重新产生了兴趣。然而,临床医生应该意识到羟氯喹中毒的危险,这是一种研究不足的情况。病例报告。我们提出一例自体中毒与20克羟氯喹在一个35岁的妇女。心脏监测显示,高剂量咪达唑仑和异丙酚启动室性心律失常,导致心律短暂正常化。由于这些心律失常的再次发生,静脉注射脂质乳剂以快速稳定心脏。开始持续使用去甲肾上腺素、氯化钾/磷酸钾和碳酸氢钠治疗。第6天,她拔管,11天后,她出院,无并发症。结论:由于缺乏高质量的科学证据,治疗方案基于氯喹毒性的经验。如果病人出现得早,建议使用活性炭。镇静用地西泮,早期通气,持续肾上腺素输注被认为是有效的治疗严重中毒。建议在替代钾时要谨慎。尽管缺乏正式的证据,但碳酸氢钠在QRS扩大的情况下似乎是有用和安全的。静脉注射脂质乳剂,伴或不伴血液透析,仍有争议,但似乎是安全的。作为最后的手段,体外生命支持可以考虑在持续的血流动力学不稳定的情况下。
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引用次数: 1
Clinical Considerations in Initial Evaluation and Treatment of Hardhead Catfish Spine Puncture Wounds. 硬头鲶鱼脊柱穿刺伤的初步评估和治疗的临床考虑。
Pub Date : 2021-03-09 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8841234
Hannah Gordon, Benjamin J Cousins, Mark A Newberry, David A Farcy

A 17-year-old male presented to our ED complaining of pain and swelling at the base of the first metacarpal after attempting to remove a catfish from his fishing line 12 hours prior to arrival. Radiographic images demonstrated a foreign body (FB), which was detectable by ultrasound. Hand surgery was consulted and took the patient to the operating room for exploration and removal of two serrated radiopaque catfish spines that were deeply embedded in the left thumb. Conclusion. Penetrating injury from hardhead catfish (Ariopsis felis) spines can cause hidden FB, envenomation, infection, and secondary damage to nearby structures. Imaging should be done for these patients to ensure they obtain timely and complete extraction of the venomous structures. Surgery should be consulted for operative management to avoid damage on removal of the catfish spine remnants.

一名17岁的男性在到达急诊室12小时前试图从鱼线上取下一条鲶鱼后,第一掌骨底部出现疼痛和肿胀。x线图像显示异物(FB),可通过超声检测到。会诊手外科,将患者带到手术室,探查并取出深嵌在左侧拇指的两根锯齿状不透射线的鲶鱼刺。结论。硬头鲶鱼(Ariopsis felis)刺的穿透性伤害可引起隐藏的FB,中毒,感染和对附近结构的二次损伤。这些患者应进行影像学检查,以确保及时、完整地取出有毒结构。应咨询外科手术处理,以避免损伤去除鲶鱼脊柱残余物。
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引用次数: 0
ACE Inhibitor Induced Isolated Angioedema of the Small Bowel: A Rare Complication of a Common Medication. ACE抑制剂引起的孤立性小肠血管性水肿:一种常见药物的罕见并发症。
Pub Date : 2021-02-13 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8853755
Marc D Squillante, Anna Trujillo, Joseph Norton, Saurabh Bansal, David Dragoo

Angioedema is a subcutaneous or submucosal tissue swelling due to capillary leakage and transudation of fluid into the interstitial tissue. It can be localized or generalized as part of a widespread reaction known as anaphylaxis. Millions of people in United States and all over the world receive ACEI antihypertensive therapy. ACEI is known to cause angioedema with an incidence of 0.7 percent. We present a case of 40-year-old female who was started on lisinopril three days prior to presentation for newly diagnosed hypertension. She presented with nonspecific severe abdominal pain, nausea, and vomiting. She denied having difficulty breathing or swelling anywhere in the body. On exam, she did not have facial, lip, tongue, or throat swelling. Her abdomen was tender without guarding or rigidity. Laboratory examination was unrevealing except for mild leukocytosis. Computed tomography scan (CT scan) of the abdomen with oral and IV contrast revealed a moderate amount of ascites with diffuse wall thickening, hyperenhancement, and mucosal edema of the entire small bowel. In the absence of any other pathology, matching history, and imaging findings highly suggestive of angioedema, she was diagnosed with isolated small bowel angioedema as a result of ACEI therapy. She was managed conservatively, and lisinopril was discontinued. A week later on follow-up, all her symptoms had resolved, and repeat CT scan showed resolution of all findings.

血管性水肿是一种皮下或粘膜下组织的肿胀,是由于毛细血管渗漏和液体进入间质组织而引起的。它可以是局部的或全身性的,作为广泛反应的一部分,被称为过敏反应。数百万人在美国和世界各地接受ACEI抗高血压治疗。已知ACEI可引起血管性水肿,发生率为0.7%。我们提出了一个40岁的女性谁是开始赖诺普利三天前的新诊断高血压的表现。她表现为非特异性严重腹痛、恶心和呕吐。她否认有呼吸困难或身体任何部位肿胀。经检查,她没有面部、嘴唇、舌头或喉咙肿胀。她的腹部有触痛,没有保护或僵硬。实验室检查除轻度白细胞增多外未见异常。腹部计算机断层扫描(CT)与口服和静脉造影剂显示中度腹水,弥漫壁增厚,高强化,整个小肠粘膜水肿。在没有任何其他病理、匹配病史和影像学表现高度提示血管性水肿的情况下,由于ACEI治疗,她被诊断为孤立性小肠血管性水肿。患者接受保守治疗,停用赖诺普利。一周后随访,所有症状均消失,复查CT显示所有症状均消失。
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引用次数: 3
A Case of Bedside Ultrasound in COVID-19 to Prognosticate Functional Lung Recovery. 1例床边超声对COVID-19患者肺功能恢复的预测。
Pub Date : 2021-01-23 eCollection Date: 2021-01-01 DOI: 10.1155/2021/8847887
Kathryn B Bartlett, Lexis T Laubach, Elizabeth M Evans, Kevin R Roth

Introduction. The fight against COVID-19 poses questions as to the clinical presentation, course, diagnosis, and treatment of the condition. This case study presents a patient infected with COVID-19 and suggests with additional research, that bedside ultrasound may be used to diagnose severity of disease and potentially, prognosticate functional lung recovery without using unnecessary resources and exposing additional healthcare professionals to infection. Case Report. A 46-year-old male presented to the emergency department (ED) with cough, fever, and shortness of breath. Chest X-ray showed patchy airspace opacities bilaterally. Rapid testing resulted positive for SARS-CoV-2. Bedside ultrasound showed abnormal lung parenchyma, with diffuse comet tail artifacts, consistent with interstitial pulmonary edema. Following a prolonged intubation, patient's abnormal lung ultrasound findings are resolved.

介绍。抗击COVID-19的斗争对该病的临床表现、病程、诊断和治疗提出了一些问题。本案例研究介绍了一名感染COVID-19的患者,并通过进一步的研究表明,床边超声可用于诊断疾病的严重程度,并可能预测肺功能恢复,而无需使用不必要的资源并使额外的医疗保健专业人员暴露于感染。病例报告。一名46岁男性以咳嗽、发烧和呼吸短促就诊于急诊科。胸部x线显示双侧空域斑片状混浊。快速检测结果为SARS-CoV-2阳性。床边超声显示肺实质异常,弥漫性彗星尾伪影,符合间质性肺水肿。经过长时间插管后,患者的异常肺部超声检查结果得到解决。
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引用次数: 0
Analysis of Sudden Death of Sympathetic Storm Caused by Coronary Artery Muscle Bridge 冠状动脉肌桥致交感风暴性猝死分析
Pub Date : 2021-01-01 DOI: 10.12677/ACREM.2021.91001
张 震东
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引用次数: 0
Effects of Tanhinone IIA on Mice with Endotoxin-Caused Acute Lung Injury 丹参酮IIA对内毒素致小鼠急性肺损伤的影响
Pub Date : 2021-01-01 DOI: 10.12677/ACREM.2021.92003
张 建国
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引用次数: 0
Expression and Role of NLRP3 Inflammasome in Tissues and Organs of Mouse with Candida albicans Sepsis NLRP3炎性体在白色念珠菌脓毒症小鼠组织器官中的表达及作用
Pub Date : 2021-01-01 DOI: 10.12677/ACREM.2021.92002
泽田 王
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引用次数: 0
Acute Myocardial Infarction (AMI) Treated with Snake Antivenom. 抗蛇毒血清治疗急性心肌梗死(AMI)。
Pub Date : 2021-01-01 DOI: 10.1155/2021/9945296
Waleed Salem, Mohamed Gafar Abdelrahim, Layth Al Majmaie, Mohammed Dahdaha, Faten Al-Bakri, Amr Elmoheen

Cardiac complications following snakebites are uncommon but fatal. Here, we discuss a case of a snakebite that led to acute myocardial infarction (AMI). Forty-five-year-old male presented to the emergency room with snakebite on the right middle finger. He was given symptomatic treatment and admitted for observation. His vital signs and initial investigations were normal except for the white blood count that was high. During observation, he developed vomiting and bradycardia. He was diagnosed with a right bundle branch block on ECG. The patient developed chest pain after a few hours and was diagnosed with AMI on ECG. The toxicology team started antivenom therapy. His troponin kept rising initially but later started coming down without percutaneous intervention (PCI). He was treated successfully with antivenom therapy and discharged.

蛇咬伤后的心脏并发症并不常见,但却是致命的。在此,我们讨论一例蛇咬伤导致急性心肌梗死(AMI)。45岁男性因右手中指被蛇咬伤被送往急诊室。给予对症治疗并留院观察。他的生命体征和初步检查正常,除了白细胞计数高。观察期间,患者出现呕吐和心动过缓。心电图诊断为右束支传导阻滞。患者于数小时后出现胸痛,心电图诊断为急性心肌梗塞。毒理学小组开始了抗蛇毒血清治疗。他的肌钙蛋白最初持续升高,但后来在没有经皮介入治疗(PCI)的情况下开始下降。经抗蛇毒血清治疗成功出院。
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引用次数: 1
Research Advances in Epilepsy Related to SCN2A Gene Mutation SCN2A基因突变与癫痫的研究进展
Pub Date : 2021-01-01 DOI: 10.12677/ACREM.2021.92004
王 潇颖
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引用次数: 0
期刊
Case Reports in Emergency Medicine
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