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Two Cardiac Arrests that Occurred after the Administration of Sugammadex: A Case of Kounis Syndrome. 两例心脏骤停发生在服用Sugammadex后:一例Kounis综合征。
Pub Date : 2020-02-17 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6590101
Machi Yanai, Koichi Ariyoshi

Kounis syndrome is a form of acute coronary syndrome caused by allergic reactions. No cases of cardiac arrest caused by Kounis syndrome that arose after the administration of sugammadex have been reported. A 71-year-old female suffered two cardiac arrests. The first occurred after sugammadex was administered at the end of an operation for a right radial distal fracture. The patient was resuscitated and transferred to our intensive care unit. She was subsequently discharged home. Five months later, she suffered a second cardiac arrest after sugammadex was administered at the end of an operation for a right femoral neck fracture at our hospital. Urgent coronary angiography revealed multiple coronary spasms. Kounis syndrome was diagnosed based on the patient's elevated serum trypsin levels and a positive result in a skin allergy test of sugammadex. In cases of cardiac arrest with unclear etiologies, Kounis syndrome should be considered.

库尼斯综合征是一种由过敏反应引起的急性冠状动脉综合征。未见使用糖麦德后因库尼斯综合征引起心脏骤停的病例报道。一名71岁女性两次心脏骤停。第一例发生在右桡骨远端骨折手术结束后使用糖麦德后。病人复苏后被转到我们的重症监护室。她随后出院回家。5个月后,在我院右侧股骨颈骨折手术结束后,患者服用糖美酮后再次发生心脏骤停。紧急冠状动脉造影显示多发冠状动脉痉挛。Kounis综合征是根据患者血清胰蛋白酶水平升高和sugammadex皮肤过敏试验阳性结果诊断的。在病因不明的心脏骤停病例中,应考虑Kounis综合征。
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引用次数: 9
Descending Necrotizing Mediastinitis Resulting from Pharyngitis with Perforation of the Aryepiglottic Fold. 下行坏死性纵隔炎,由咽炎伴动脉瓣襞穿孔引起。
Pub Date : 2020-02-13 eCollection Date: 2020-01-01 DOI: 10.1155/2020/4963493
Alexandra Pulst-Korenberg, Stephen C Morris

Descending necrotizing mediastinitis and pharyngeal perforation are uncommon complications of pharyngitis that are associated with high morbidity and mortality. This case report describes a previously healthy 18-year-old male who presented to the emergency room with 5 days of severe sore throat, intermittent fevers, and vomiting and was found to have extensive posterior pharyngeal and mediastinal air along with extravasation of contrast on computed tomography, consistent with perforation of the left aryepiglottic fold as well as descending necrotizing mediastinitis. The patient had a complicated hospital course including multiple operative interventions, abscess formation, and development of pericardial and pleural effusions. Successful treatment required swift resuscitation including broad-spectrum antibiotics and significant coordination of emergent operative intervention between otolaryngology and cardiothoracic surgery. It is important to recognize descending necrotizing mediastinitis as a clinical entity that may result from oropharyngeal infections as early intervention significantly decreases subsequent complications and mortality. Furthermore, pharyngeal perforation is an extremely rare complication which requires either CT with oral contrast or esophagram for diagnosis.

下行坏死性纵隔炎和咽部穿孔是咽炎的罕见并发症,具有很高的发病率和死亡率。本病例报告描述了一名先前健康的18岁男性,他以5天的严重喉咙痛、间歇性发烧和呕吐就诊于急诊室,并在计算机断层扫描上发现咽后腔和纵隔有广泛的空气,并伴有造影剂外渗,与左动脉- piglottic襞穿孔和降性坏死性纵隔炎一致。患者的住院过程复杂,包括多次手术干预、脓肿形成、心包和胸腔积液的发展。成功的治疗需要快速复苏,包括广谱抗生素和耳鼻喉科和心胸外科之间紧急手术干预的重要协调。认识到下行坏死性纵隔炎作为一种可能由口咽感染引起的临床实体是很重要的,因为早期干预可以显著减少随后的并发症和死亡率。此外,咽穿孔是一种极为罕见的并发症,需要CT结合口腔造影或食管造影诊断。
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引用次数: 3
Lateral Malleolar Fracture with Concurrent Achilles Tendon Rupture: A Case Report and Literature Review. 外踝骨折并发跟腱断裂1例报告及文献复习。
Pub Date : 2020-02-11 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6479140
Leslie H Pyle, Raed W Al-Gharib, Erik C Kissel

Achilles tendon and malleolar fractures are commonly seen in isolation, but only a few cases of combined injuries have been reported. In this case, we present a 53-year-old male who sustained an isolated lateral malleolus fracture with an Achilles tendon rupture. Emergency Medicine physicians should consider the possibility of these injuries in combination.

跟腱和踝骨折通常是孤立的,但只有少数病例的合并损伤已被报道。在这个病例中,我们报告了一位53岁的男性,他患有孤立的外踝骨折并跟腱断裂。急诊医师应考虑这些损伤合并的可能性。
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引用次数: 1
Hypercalcemic Encephalopathy as an Initial Presentation of Multiple Myeloma. 高钙血症性脑病是多发性骨髓瘤的初始表现。
Pub Date : 2020-02-08 eCollection Date: 2020-01-01 DOI: 10.1155/2020/4746865
Durga Shankar Meena, Gopal Krishana Bohra, Mahendra Kumar Garg, Abhishek Purohit, Deepak Kumar, Swapnil Tripathi

We report the case of an 84-year-old female presented to us with acute onset altered sensorium. On investigation, neurological and infectious causes were ruled out. On further evaluation, her serum calcium was found elevated (15.07 gm/dl). The diagnosis of hypercalcemic encephalopathy was made with the possibility of multiple myeloma due to raised total protein and globulin levels. Serum electrophoresis, immunofixation, and bone marrow examination confirmed the diagnosis of multiple myeloma. The patient was treated with bortezomib, dexamethasone, and lenalidomide. After 1 week, she improved with normalization of serum calcium. Herein, we highlight hypercalcemia as an important cause of encephalopathy. As our report suggests, metabolic encephalopathy can be the first presentation in multiple myeloma.

我们报告的情况下,84岁的女性提出了我们的急性发作改变感觉。经调查,排除了神经和感染原因。进一步检查发现她的血钙升高(15.07 gm/dl)。由于总蛋白和球蛋白水平升高,诊断为高钙血症性脑病,可能为多发性骨髓瘤。血清电泳,免疫固定,骨髓检查证实多发性骨髓瘤的诊断。患者给予硼替佐米、地塞米松和来那度胺治疗。1周后,患者血钙恢复正常。在此,我们强调高钙血症是脑病的一个重要原因。正如我们的报告所提示的,代谢性脑病可能是多发性骨髓瘤的第一个表现。
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引用次数: 1
Brain Abscess Secondary to a Dental Infection. 继发于牙齿感染的脑脓肿。
Pub Date : 2020-02-06 eCollection Date: 2020-01-01 DOI: 10.1155/2020/3248174
Léonor Costa Mendes, Frédéric Vaysse, Delphine Maret

The risk of a brain abscess is a complication of odontogenic infection that is rarely considered by physicians and little spoken of, yet treating dental infections may avoid a potentially life-threatening condition. We report a case of 7-year-old boy with a brain abscess secondary to a dental infection. He was immediately taken to the operating theatre for drainage and cleaning of the abscess. A dental examination revealed root abscesses on temporary molars, which were extracted under general anaesthetic. Two months after his admission, the child was switched to oral antibiotherapy and could return home. A brain abscess represents a life-threatening disease. Childhood brain abscess is uncommon but may be encountered by all physicians and students as a clinical emergency. It is indispensable that physicians finding symptoms similar to those in this case study refer the patient for emergency care and that possible dental foci of infection be assessed, whether or not the patient is being followed for dental care.

脑脓肿的风险是牙源性感染的并发症,医生很少考虑到这一点,也很少提及,但治疗牙齿感染可能避免潜在的危及生命的情况。我们报告一个7岁男孩继发于牙齿感染的脑脓肿病例。他立即被带到手术室进行引流和清洗脓肿。牙科检查发现临时磨牙牙根脓肿,在全身麻醉下拔除。入院两个月后,该儿童改用口服抗生素治疗,可以回家了。脑脓肿代表一种危及生命的疾病。儿童脑脓肿是罕见的,但可能遇到所有的医生和学生作为临床急诊。当医生发现与本病例研究中类似的症状时,必须将患者转诊至急诊,并评估可能的牙齿感染灶,无论患者是否正在接受牙科治疗。
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引用次数: 4
The Untimely Popping Phial: Poppers as an Unusual Cause of Skin Corrosion of the Thigh. 不合时宜的破瓶:破瓶器是大腿皮肤腐蚀的不寻常原因。
Pub Date : 2020-01-30 eCollection Date: 2020-01-01 DOI: 10.1155/2020/2058624
Fabienne Moret, Gregor Lindner, Bertram K Woitok

Background: Alkyl nitrites or "poppers" are widely used as sex-drugs due to their aphrodisiac and muscle relaxant effects. We describe the rare case of a large-sized dermatitis after direct skin contact with the poppers-fluid in a poppers user. Case Presentation. A 52-year-old patient presented to the emergency department due to burning pain on his proximal right thigh and scrotum. Clinical examination showed an 8 × 5 cm measuring burning wound resembling lesion. During further history the patient mentioned that the day before presentation a "poppers" phial unintentionally opened in his pocket and the fluid leaked.

Conclusions: The present case shows severe skin defects after skin-contact with alkyl nitrates in a "poppers" user. Maculopathy and methemoglobinemia are prominent unwanted side effects of "poppers" use. However, our report demonstrates that attention should also be paid to potential harm for the skin.

背景:烷基亚硝酸盐或“poppers”因其壮阳和肌肉松弛作用而被广泛用作性药物。我们描述了一个罕见的情况下,一个大尺寸的皮炎后直接皮肤接触的poppers-液体在poppers用户。案例演示。一位52岁的病人因右大腿近端及阴囊灼痛而到急诊科就诊。临床检查显示一8 × 5 cm的烧伤创面,类似病变。在进一步的病史中,病人提到,在发病前一天,他的口袋里无意中打开了一个“poppers”小瓶,液体漏了出来。结论:本病例显示严重的皮肤缺陷后皮肤接触烷基硝酸盐“poppers”用户。黄斑病变和高铁血红蛋白血症是“poppers”使用的突出不良副作用。然而,我们的报告表明,还应注意对皮肤的潜在危害。
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引用次数: 3
Epileptic Seizure from Ginkgo Nut Intoxication in an Adult. 成人因银杏中毒致癫痫发作。
Pub Date : 2020-01-28 eCollection Date: 2020-01-01 DOI: 10.1155/2020/5072954
Yoshinori Kosaki, Hiromichi Naito, Tsuyoshi Nojima, Atsunori Nakao

The ginkgo tree is a well-known, highly adaptable urban plant. Ginkgo nuts are the product of the ginkgo tree. Interior ginkgo nuts are cooked and served in Asian countries; however, the potential toxicity of the gingko nuts is not commonly known. Herein, we report a 48-year-old male patient experiencing acute convulsions presumably due to overconsumption of gingko nuts. The patient was transferred to our department after several episodes of acute generalized tonicclonic seizures lasting approximately 30 seconds each and starting one hour before the visit. The patient also complained of vomiting, vertigo, diarrhea, and tremors in both upper limbs following the seizures. Elevated 4-O-methylpyridoxine (312 ng/mL), low blood pyridoxal phosphate (2.4 μg/L), and low vitamin B1 (20 ng/mL) levels were found in the blood analysis. No other remarkable abnormalities were detected. We diagnosed the patient with ginkgo nut intoxication, and he was orally administered 400 mg of pyridoxal phosphate. His symptoms resolved after treatment, and no seizures recurred thereafter. Our report may help raise awareness of the clinical presentation and management of this intoxication among emergency physicians.

银杏树是一种众所周知的适应性很强的城市植物。银杏果是银杏树的产物。在亚洲国家,室内银杏被烹饪和食用;然而,银杏的潜在毒性并不为人所知。在此,我们报告一位48岁的男性患者,可能由于过度食用银杏而出现急性惊厥。患者在就诊前一小时出现几次急性全身性强直阵挛发作,每次持续约30秒,随后转至我科。患者还主诉癫痫发作后出现呕吐、眩晕、腹泻和双上肢震颤。血液分析发现4- o -甲基吡哆醇升高(312 ng/mL),血中磷酸吡哆醛低(2.4 μg/L),维生素B1低(20 ng/mL)。未发现其他明显异常。我们诊断患者为银杏中毒,并给予口服400毫克磷酸吡哆醛。治疗后症状消失,此后无癫痫复发。我们的报告可能有助于提高认识的临床表现和管理这种中毒在急诊医生。
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引用次数: 9
Aspergilloma Superimposed Infection on Lymphoid Interstitial Pneumonia. 淋巴间质性肺炎曲菌肿叠加感染。
Pub Date : 2020-01-18 eCollection Date: 2020-01-01 DOI: 10.1155/2020/3151036
Daniel Tran, Rajagopalan Rengan, James Lee, Alan Lucerna, James Espinosa

We describe a case of a 27-year-old female without any prior underlying immunodeficiency syndromes who presented with hemoptysis secondary to subacute invasive pulmonary aspergillosis and subsequently diagnosed with lymphoid interstitial pneumonia (LIP). CT chest demonstrated bilateral interstitial disease with patchy opacities and multiple large cysts and bullae. Diagnosis was confirmed histologically after surgical lung resection of the mycetoma containing cavitation. Therefore, LIP should be suspected in patients presenting with opportunistic infections in the setting of cystic lung disease.

我们描述了一个27岁的女性病例,没有任何潜在的免疫缺陷综合征,她以亚急性侵袭性肺曲霉病继发咯血,随后被诊断为淋巴样间质性肺炎(LIP)。胸部CT示双侧间质病变伴斑片状混浊及多发大囊肿和大泡。肺切除术后病理证实为肺内空化菌足肿。因此,在囊性肺疾病背景下出现机会性感染的患者应怀疑LIP。
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引用次数: 0
Cardiac Syncope with Anoxic Seizure Activity. 心脏性晕厥伴缺氧发作活动。
Pub Date : 2020-01-08 eCollection Date: 2020-01-01 DOI: 10.1155/2020/6749382
Samed Talibi, Craig Douglas, Benjamin Pope

This is a case report, which explores the presentation to the emergency department of a fit and well female with a known ventricular bigeminy. She presented with convulsive episodes. The working differential diagnosis was of possible cardiac syncope with anoxic seizure activity or neurogenically mediated arrhythmia secondary to subarachnoid haemorrhage. On further collateral history, the patient was on citalopram. The ECGs demonstrated PVCs of multiple morphologies that were transiently bidirectional, raising the possibility of catecholaminergic polymorphic ventricular tachycardia. The presentation of a young fit patient with syncope and seizure-like episodes should always raise concern for the admitting emergency medicine clinician of an underlying cardiac pathology.

这是一个病例报告,其中探讨的介绍到急诊科健康和良好的女性与已知的心室重症症。她出现抽搐发作。鉴别诊断为可能的心源性晕厥伴缺氧发作活动或继发于蛛网膜下腔出血的神经源性心律失常。在进一步的侧支病史中,患者正在服用西酞普兰。心电图显示短暂双向的多种形态室性早搏,增加了儿茶酚胺能多形性室性心动过速的可能性。一个年轻的病人晕厥和癫痫样发作的表现应该引起急诊临床医生对潜在心脏病理的关注。
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引用次数: 0
Immune Associated Myocarditis: A Report of 2 Cases and Literature Review 免疫性心肌炎2例报告并文献复习
Pub Date : 2020-01-01 DOI: 10.12677/ACREM.2020.83005
志峰 冯
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引用次数: 0
期刊
Case Reports in Emergency Medicine
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