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Laser Atherectomy and Restenting of the Superficial Femoral Artery Using GORE VIABAHN Endoprosthesis Following Failure of Both Bare-Metal Stenting and Surgical Revascularization. 在裸金属支架植入术和手术血管再通术失败后,使用 GORE VIABAHN 内支架对股浅动脉进行激光粥样斑块切除术和再支架植入术。
Pub Date : 2024-11-05 eCollection Date: 2024-01-01 DOI: 10.1155/2024/4950420
Ahmed Khawer, Claro F Diaz

Peripheral arterial disease (PAD) affects more than 230 million adults worldwide. Revascularization via angioplasty is a common method to manage stenosis in the superficial femoral artery (SFA). In-stent restenosis, however, is a common complication in endovascular interventions, especially in the SFA. Here, we present a case that involves recanalization of the SFA in a patient with a previously occluded stent and failed surgical revascularization. This patient initially presented with an occluded SFA which was stented. Four years later, the stent was reoccluded and surgical endarterectomy of the artery was performed with partial removal of the stent. Ten years later, the SFA is again occluded. Recanalization of the SFA using laser atherectomy and restenting of the occluded stent with GORE VIABAHN endoprosthesis was performed successfully. The combination of such methods is a suitable way to manage chronic lesions and minimize restenosis in patients with PAD.

全世界有超过 2.3 亿成年人患有外周动脉疾病(PAD)。通过血管成形术进行血管重建是治疗股浅动脉(SFA)狭窄的常用方法。然而,支架内再狭窄是血管内介入治疗的常见并发症,尤其是在股浅动脉。在此,我们介绍了一个病例,该病例涉及对一名曾因支架闭塞和手术血管再通失败的患者进行 SFA 再通。该患者最初因SFA闭塞而植入支架。四年后,支架再次闭塞,于是进行了动脉内膜剥脱手术,并移除了部分支架。十年后,SFA 再次闭塞。使用激光动脉粥样硬化切除术对 SFA 进行了再通路,并使用 GORE VIABAHN 内支架对闭塞的支架进行了再置入,手术取得了成功。将这些方法结合起来是治疗慢性病灶和减少 PAD 患者再狭窄的合适方法。
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引用次数: 0
Vulvar Lymphangioma Arising in the Setting of May-Thurner Syndrome. 梅-特纳综合征背景下出现的外阴淋巴管瘤
Pub Date : 2024-09-18 eCollection Date: 2024-01-01 DOI: 10.1155/2024/9761009
Surekha Bantumilli, Ian Flyke, Muthu Kumar Sakthivel, Christine E Bookhout

This case report describes an instance of vulvar lymphangioma occurring in the setting of May-Thurner syndrome (MTS), an association between two vascular conditions that we do not believe has been previously reported. Lymphangioma, also known as lymphatic malformation, is a benign lesion typified by dilatation of endothelial-lined lymphatic channels involving the skin and subcutis, which can occur either as a congenital abnormality or as a result of acquired damage to lymphatic channels. Lymphangioma is a rare lesion in the vulva. MTS, also known as iliac vein compression syndrome or Cockett's syndrome, is a condition of left iliac vein obstruction due to overriding the right common iliac artery which can lead to iliofemoral deep vein thrombosis. In this report, we describe the case of a 29-year-old woman with MTS diagnosed at 7 years of age with poor lymphatic drainage and pelvic pain requiring left iliac vein stenting. She presented with left vulvar discomfort and chronic lower extremity edema and was found to have warty vulvar masses, with histopathological examination showing lymphangioma of the vulva. We believe that this is the first report of vulvar lymphangioma recognized in the setting of MTS, and we will discuss the clinical features, etiology, and possible pathophysiologic association between these two entities.

本病例报告描述了一例在梅-特纳综合征(MTS)的情况下发生的外阴淋巴管瘤,我们认为这两种血管疾病之间的关联以前从未报道过。淋巴管瘤又称淋巴畸形,是一种良性病变,其特征是内皮衬里淋巴管扩张,累及皮肤和皮下组织。淋巴管瘤是一种罕见的外阴病变。MTS又称髂静脉压迫综合征或科克特综合征,是由于右侧髂总动脉压迫左侧髂静脉导致左侧髂静脉阻塞的一种病症,可导致髂股深静脉血栓形成。在本报告中,我们描述了一例 29 岁女性 MTS 患者的病例,她在 7 岁时被诊断为淋巴引流不畅和盆腔疼痛,需要进行左髂静脉支架植入术。她出现左侧外阴不适和慢性下肢水肿,被发现有疣状外阴肿块,组织病理学检查显示为外阴淋巴管瘤。我们认为这是第一例在 MTS 的情况下发现外阴淋巴管瘤的报告,我们将讨论这两种实体的临床特征、病因和可能的病理生理关联。
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引用次数: 0
Beyond Abdominal Pain: Decoding the Mysteries of Nutcracker Syndrome. 超越腹痛:破解胡桃夹子综合征之谜》。
Pub Date : 2024-07-25 eCollection Date: 2024-01-01 DOI: 10.1155/2024/8702202
Usamah Al-Anbagi, Abdulrahman Saad, Abdulqadir J Nashwan

Nutcracker syndrome (NCS), a rare but impactful vascular condition, emerges from the compression of the left renal vein by adjacent major arteries, leading to a diverse array of symptoms such as hematuria, flank pain, and renal challenges. Highlighting the case of a 30-year-old male with an atypical presentation of NCS, this report explores the diagnostic complexities arising from its varied presentations and therapeutic options. It emphasizes the critical role of computed tomography (CT) in unveiling the underlying vascular constriction. Through this lens, the case underscores the necessity of considering NCS in the differential diagnosis of abdominal pain, advocating for a prompt and accurate diagnosis to guide effective management strategies, ranging from conservative approaches to surgical intervention. This stresses the importance of heightened awareness and ongoing research for optimizing patient outcomes in the face of this elusive condition.

胡桃钳综合征(NCS)是一种罕见但影响巨大的血管疾病,是由于左肾静脉受到邻近大动脉的压迫而引起的,会导致血尿、侧腹疼痛和肾脏问题等一系列症状。本报告以一名 30 岁男性的非典型 NCS 病例为重点,探讨了其不同表现和治疗方案所带来的诊断复杂性。报告强调了计算机断层扫描(CT)在揭示潜在血管收缩方面的关键作用。通过这一视角,该病例强调了在腹痛的鉴别诊断中考虑 NCS 的必要性,主张及时准确的诊断以指导有效的治疗策略,包括保守治疗和手术干预。这强调了面对这种难以捉摸的病症,提高意识和持续研究对于优化患者预后的重要性。
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引用次数: 0
“Complete Venous Shutdown:” A Rare Case of Combined Superior Vena Cava (SVC) and Inferior Vena Cava (IVC) Occlusion "静脉完全闭塞:"上腔静脉(SVC)和下腔静脉(IVC)合并闭塞的罕见病例
Pub Date : 2023-12-15 DOI: 10.1155/2023/5590280
M. K. Malik, Wajahat Humayun, Amir Darki
Independently, superior vena cava (SVC) occlusion and inferior vena cava (IVC) occlusion are usually seen in the setting of SVC syndrome and iliocaval venous obstruction (ICVO), respectively. Concomitant occlusion of the SVC and IVC is rare and most commonly seen in the setting of malignancy or other hypercoagulable states. Venous hypertension can lead to the formation of “downhill” varices in the esophagus and can be a rare source of gastrointestinal bleeding. We present a rare case of combined SVC and IVC occlusion and its management.
上腔静脉(SVC)闭塞和下腔静脉(IVC)闭塞通常分别独立出现在上腔静脉综合征和髂腔静脉阻塞(ICVO)的情况下。SVC和IVC同时闭塞的情况很少见,最常见于恶性肿瘤或其他高凝状态。静脉高压可导致食管形成 "下坡 "静脉曲张,是罕见的消化道出血来源。我们介绍了一例合并 SVC 和 IVC 闭塞的罕见病例及其治疗方法。
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引用次数: 0
Postcarotid Endarterectomy Hematoma Induced Arrhythmia: Report of a Rare Case 颈动脉内膜切除术后血肿诱发心律失常:罕见病例报告
Pub Date : 2023-12-04 DOI: 10.1155/2023/4633731
G. Galyfos, A. Chamzin, F. Sigala, K. Filis
Postcarotid endarterectomy (CEA) hematomas are common although they are rarely threatening and necessitate reoperation. We aim to report a rare case of an expanding hematoma that caused a cardiac arrhythmia (bigeminy) which was reversed after hematoma evacuation.
颈动脉内膜切除术(CEA)后血肿是常见的,虽然他们很少威胁和需要再次手术。我们的目的是报告一个罕见的病例扩大血肿,导致心律失常(重症肌痛),并在血肿清除后逆转。
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引用次数: 0
Angiographic and Clinical Impact of Novel Revascularization for Occluded Femoropopliteal Prosthetic Bypass Graft: A Combination of Surgical Thrombectomy and Drug-Coated Balloon Angioplasty. 血管造影和新型血运重建对闭塞股腘假体旁路移植术的临床影响:手术取栓和药物包被球囊血管成形术的结合。
Pub Date : 2023-11-21 eCollection Date: 2023-01-01 DOI: 10.1155/2023/6730220
Tatsuro Takei, Takashi Kajiya, Keisuke Yamamoto, Junichiro Takaoka, Yoshihiko Atsuchi, Nobuhiko Atsuchi

Background: Previous reports have revealed various endovascular intervention techniques for prosthetic femoropopliteal bypass occlusion (PFPBO); however, treatment for PFPBO remains challenging for most interventionalists and vascular surgeons because the procedure is complicated. Most of the reported techniques involve device implantation. In the present study, we performed a combination of surgical graft thrombectomy and drug-coated balloon angioplasty for PFPBO without implanting any additional devices. Furthermore, we determined the favorable long-term results of this treatment using follow-up angiography. Case Presentation. A 77-year-old man with a history of chronic kidney disease and coronary artery disease presented to our clinic with rest pain on his left leg. Seven years prior to the current consult, he underwent femoropopliteal bypass (FPB) surgery using a prosthetic graft due to in-stent occlusion of the left superficial femoral artery (SFA). Four years after surgery, a duplex ultrasound scan revealed stenosis of the proximal anastomosis site; hence, medical therapy was continued. On the current consult, diagnostic angiography revealed occlusion of the FPB and infrapopliteal vessels. In the first attempt at recanalization, the guidewire was unable to pass through the occluded SFA. Therefore, another technique was performed to revascularize the FPBO and infrapopliteal vessels. We obtained an angiography of the left leg after inserting the guiding sheath via the right common femoral artery (CFA). First, surgical thrombectomy using a Fogarty catheter via the exposed left CFA was performed. Following endovascular therapy via the right CFA, we performed drug-coated balloon angioplasty for anastomotic stenosis and recanalized occlusive infrapopliteal vessels. Restenosis was not observed on follow-up angiograms. On further follow-up angiography, there was notable regression of the residual stenosis at the proximal anastomosis of the prosthetic graft.

Conclusion: This novel revascularization strategy may be a viable treatment option for PFPBO.

背景:先前的报道已经揭示了人工股腘动脉旁路闭塞(PFPBO)的各种血管内介入技术;然而,对于大多数介入医师和血管外科医生来说,PFPBO的治疗仍然具有挑战性,因为手术过程复杂。大多数报道的技术涉及装置植入。在本研究中,我们在不植入任何额外装置的情况下,对PFPBO进行了外科移植取栓和药物包被球囊血管成形术的联合治疗。此外,我们通过随访血管造影确定了这种治疗的良好长期结果。案例演示。一名77岁男性,有慢性肾脏疾病和冠状动脉疾病病史,左腿静止疼痛。在本次会诊的七年前,由于支架内左股浅动脉(SFA)闭塞,他接受了股腘动脉搭桥(fbp)手术。术后四年,超声扫描显示近端吻合口狭窄;因此,继续进行药物治疗。在目前的咨询中,诊断性血管造影显示FPB和髌下血管闭塞。在第一次再通的尝试中,导丝无法通过阻塞的SFA。因此,采用另一种技术来重建FPBO和腘窝下血管。我们通过右股总动脉(CFA)插入引导鞘后进行了左腿血管造影。首先,通过暴露的左侧CFA使用Fogarty导管进行手术取栓。在通过右侧CFA进行血管内治疗后,我们对吻合口狭窄和闭塞的腘下血管进行了药物包被球囊血管成形术。随访血管造影未见再狭窄。在进一步的随访血管造影中,义肢近端吻合口残余狭窄明显消退。结论:这种新的血运重建策略可能是治疗PFPBO的一种可行的选择。
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引用次数: 0
Peripheral Arteriovenous Malformation Embolization Using Squid. 鱿鱼栓塞治疗外周动静脉畸形。
Pub Date : 2023-09-30 eCollection Date: 2023-01-01 DOI: 10.1155/2023/8858656
Saima Ahmad, Moeez Uddin

Materials and methods: Between January 2018 and December 2020, twenty patients (7 men and 13 women) with peripheral high-flow arteriovenous malformations who were treated primarily with arterial embolization using squid were retrospectively included. Anatomical sites being treated included the head and neck (16), extremities (2), uterus (1), and pelvis (1). Squid was used as the sole embolic agent in 15 patients, and transarterial embolization was employed in all cases except one where direct puncture embolization was used. Treatments were delivered over one or two sessions, with or without surgery. A total of 27 sessions were carried out with an interval time ranging from 6 to 36 months between sessions.

Results: Technical success was achieved in all cases. In those patients treated with squid alone, 13 exhibited total devascularization following embolization, and a further 4 required surgical excision to achieve complete obliteration of the arteriovenous malformation. There were no major complications, cases of microcatheter entrapment, or dimethyl sulfoxide-related pain recorded. On follow-up, one patient reported persistent pain, and another patient developed a garlicky taste. All other patients reported complete resolution of symptoms following treatment.

Conclusion: This study demonstrates the successful use of squid in managing peripheral arteriovenous malformations with low complication rates and long-term stable results, therefore validating its efficacy when used alone or in combination with other embolic agents. Squid may be the preferred embolic agent in any interventional radiologist's armamentarium as it offers formulations with varying viscosities (squid-18 and squid-12). We conclude that squid should be considered as a first-line embolic agent in the management of peripheral arteriovenous malformations.

材料和方法:在2018年1月至2020年12月期间,回顾性纳入了20名外周高流量动静脉畸形患者(7名男性和13名女性),这些患者主要接受了鱿鱼动脉栓塞治疗。接受治疗的解剖部位包括头颈部(16)、四肢(2)、子宫(1)和骨盆(1)。15例患者使用Squid作为唯一的栓塞剂,除一例使用直接穿刺栓塞外,所有病例均采用经动脉栓塞。治疗分为一到两个疗程,有无手术。共进行了27次会议,会议间隔时间为6至36个月。结果:所有病例均取得了技术上的成功。在那些单独使用乌贼治疗的患者中,13名患者在栓塞后表现出完全断流,另有4名患者需要手术切除才能完全闭塞动静脉畸形。无重大并发症、微导管卡压病例或二甲基亚砜相关疼痛记录。在随访中,一名患者报告持续疼痛,另一名患者出现蒜味。所有其他患者均报告治疗后症状完全缓解。结论:本研究证明了squid在治疗外周动静脉畸形方面的成功应用,并发症发生率低,结果长期稳定,因此验证了其单独使用或与其他栓塞剂联合使用的疗效。鱿鱼可能是任何介入放射科医生的医疗器械中的首选栓塞剂,因为它提供具有不同粘度的制剂(鱿鱼-18和鱿鱼-12)。我们的结论是,鱿鱼应被视为治疗外周动静脉畸形的一线栓塞剂。
{"title":"Peripheral Arteriovenous Malformation Embolization Using Squid.","authors":"Saima Ahmad,&nbsp;Moeez Uddin","doi":"10.1155/2023/8858656","DOIUrl":"10.1155/2023/8858656","url":null,"abstract":"<p><strong>Materials and methods: </strong>Between January 2018 and December 2020, twenty patients (7 men and 13 women) with peripheral high-flow arteriovenous malformations who were treated primarily with arterial embolization using squid were retrospectively included. Anatomical sites being treated included the head and neck (16), extremities (2), uterus (1), and pelvis (1). Squid was used as the sole embolic agent in 15 patients, and transarterial embolization was employed in all cases except one where direct puncture embolization was used. Treatments were delivered over one or two sessions, with or without surgery. A total of 27 sessions were carried out with an interval time ranging from 6 to 36 months between sessions.</p><p><strong>Results: </strong>Technical success was achieved in all cases. In those patients treated with squid alone, 13 exhibited total devascularization following embolization, and a further 4 required surgical excision to achieve complete obliteration of the arteriovenous malformation. There were no major complications, cases of microcatheter entrapment, or dimethyl sulfoxide-related pain recorded. On follow-up, one patient reported persistent pain, and another patient developed a garlicky taste. All other patients reported complete resolution of symptoms following treatment.</p><p><strong>Conclusion: </strong>This study demonstrates the successful use of squid in managing peripheral arteriovenous malformations with low complication rates and long-term stable results, therefore validating its efficacy when used alone or in combination with other embolic agents. Squid may be the preferred embolic agent in any interventional radiologist's armamentarium as it offers formulations with varying viscosities (squid-18 and squid-12). We conclude that squid should be considered as a first-line embolic agent in the management of peripheral arteriovenous malformations.</p>","PeriodicalId":9632,"journal":{"name":"Case Reports in Vascular Medicine","volume":"2023 ","pages":"8858656"},"PeriodicalIF":0.0,"publicationDate":"2023-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10560117/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41100920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relapsing TIPIC Syndrome after Administration of an mRNA-Based COVID-19 Vaccine. 施用基于mRNA的新冠肺炎疫苗后的复发性TIPIC综合征。
Pub Date : 2023-09-13 eCollection Date: 2023-01-01 DOI: 10.1155/2023/6679200
Georgiana C Sandu, Gregor Weisser, Stefan Krämer, Matthias Reinhard

Reported vascular complications following mRNA-based COVID-19 vaccines are consisting of myocarditis, cerebral venous thrombosis, cerebral vascular thrombosis, and vaccine-induced thrombocytopenia. Here, we describe a case of a 49-year-old woman with left-sided pain above the middle common carotid artery (carotidynia) starting a few days after her second vaccination with an mRNA-based COVID-19 vaccine (Spikevax). Imaging was indicative of transient perivascular inflammation of the carotid artery (TIPIC) syndrome. The diagnostic workup for other immunologically mediated diseases was negative. The inflammation subsided after a course of prednisone and aspirin, and clinical symptoms vanished, but later mildly relapsed in the context of a viral upper respiratory tract infection other than SARS-CoV-2. Carotidynia because of TIPIC syndrome may present as an immunogenic side effect of the newly developed mRNA-based vaccinations against COVID-19. TIPIC syndrome should be considered in new-onset neck pain after vaccination.

基于mRNA的新冠肺炎疫苗后报告的血管并发症包括心肌炎、脑静脉血栓形成、脑血管血栓形成和疫苗诱导的血小板减少症。在这里,我们描述了一例49岁的女性在第二次接种基于mRNA的新冠肺炎疫苗(Spikevax)几天后开始出现颈总动脉中部以上左侧疼痛(颈动脉狭窄)的病例。影像学表现为颈动脉短暂性血管周围炎症(TIPIC)综合征。其他免疫介导疾病的诊断结果为阴性。服用泼尼松和阿司匹林一个疗程后,炎症消退,临床症状消失,但后来在严重急性呼吸系统综合征冠状病毒2型以外的病毒性上呼吸道感染中轻度复发。TIPIC综合征引起的颈动脉综合征可能是新开发的基于mRNA的新冠肺炎疫苗的免疫原性副作用。接种疫苗后新发的颈部疼痛应考虑TIPIC综合征。
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引用次数: 0
Removal of Wall-Adherent Inferior Vena Cava Thrombus with a Combined Approach Using Vacuum-Assisted Thrombectomy and a Rotational Thrombectomy Device. 采用真空辅助取栓和旋转取栓装置联合入路去除壁挂式下腔静脉血栓。
Pub Date : 2023-01-01 DOI: 10.1155/2023/5178998
Julius Kaemmel, Roland Heck, Pia Lanmüller, Volkmar Falk, Christoph Starck

Introduction. Large thrombi in the inferior vena cava pose a high risk for a pulmonary embolism. Percutaneous extracorporeal circulation-based vacuum-assisted thrombus aspiration is a viable option for removal. Wall adherence of thrombotic material can compromise procedural success. Case Report. A 46-year-old female presented with a subtotal thrombotic occlusion of the inferior vena cava and the proximal right common iliac vein after weaning from extracorporeal life support. Due to severe wall adherence of the thrombotic material, the patient was treated with the combination of percutaneous extracorporeal circulation-based thrombus aspiration using the AngioVac system and a rotational thrombectomy device.

介绍。下腔静脉的大血栓是肺栓塞的高危因素。基于体外循环的真空辅助血栓抽吸是一种可行的移除方法。血栓物质粘附壁会影响手术的成功。病例报告。一个46岁的女性提出了一个次全血栓闭塞下腔静脉和右髂总静脉近端后,脱离体外生命支持。由于血栓物质的严重壁粘附,患者接受了使用AngioVac系统和旋转取栓装置经皮体外循环取栓的联合治疗。
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引用次数: 0
Penile Livedoid Vasculopathy: First Reported Case. 阴茎活体样血管病变:首例报道。
Pub Date : 2023-01-01 DOI: 10.1155/2023/6920383
Ahmad Hallak, William Bennett, Mohammed Adib Tanbir, Supriya R Donthamsetty, Bethaney Vincent

Livedoid vasculopathy is a thromboocclusive cutaneous vasculopathy manifested by livedoid changes, atrophie blanche, and ulceration. The pathogenesis is speculated to involve increasing coagulation or impaired thrombolysis leading to the occlusion of dermal blood vessels with fibrin thrombi. Livedoid vasculopathy is known to primarily affect the lower extremities. We report the first case of livedoid vasculopathy affecting the penis. A 60-year-old male was evaluated for a split urine stream with associated irritation and peeling of the skin of the glans penis. His penile ulcer continued to enlarge despite steroids and antibiotics. Due to diagnostic uncertainty, a biopsy was performed which revealed hyaline thrombi within the lumens of small vessels within the upper to mid dermis, fibrinoid material in the walls of these blood vessels and within the perivascular stroma with overlying and adjacent epidermal spongiosis, and mild perivascular lymphocytic infiltrate with a few scattered neutrophils most consistent with livedoid vasculitis. He was started on aspirin and pentoxifylline with limited improvement and was later started on apixaban with near-complete resolution in 6 months. Penile livedoid vasculopathy has not been previously reported in the English literature. Early diagnosis and treatment are imperative to limit morbidity.

活体样血管病变是一种血栓闭塞性皮肤血管病变,表现为活体样改变、白色萎缩和溃疡。其发病机制推测与凝血增加或溶栓受损导致纤维蛋白血栓阻塞真皮血管有关。类活体血管病变已知主要影响下肢。我们报告第一例活体样血管病变影响阴茎。一个60岁的男性被评估为分裂的尿流与相关的刺激和脱皮的皮肤龟头阴茎。尽管使用类固醇和抗生素,他的阴茎溃疡仍在扩大。由于诊断不确定,活检显示真皮上部至中部小血管管腔内可见透明血栓,这些血管壁和血管周围间质内可见纤维蛋白样物质,伴上覆和邻近表皮海绵状病变,血管周围有轻度淋巴细胞浸润,有少量分散的中性粒细胞,与类活体血管炎最一致。他开始服用阿司匹林和己酮茶碱,改善有限,后来开始服用阿哌沙班,6个月后几乎完全缓解。阴茎活体样血管病变在英国文献中尚未见报道。早期诊断和治疗是限制发病率的必要条件。
{"title":"Penile Livedoid Vasculopathy: First Reported Case.","authors":"Ahmad Hallak,&nbsp;William Bennett,&nbsp;Mohammed Adib Tanbir,&nbsp;Supriya R Donthamsetty,&nbsp;Bethaney Vincent","doi":"10.1155/2023/6920383","DOIUrl":"https://doi.org/10.1155/2023/6920383","url":null,"abstract":"<p><p>Livedoid vasculopathy is a thromboocclusive cutaneous vasculopathy manifested by livedoid changes, atrophie blanche, and ulceration. The pathogenesis is speculated to involve increasing coagulation or impaired thrombolysis leading to the occlusion of dermal blood vessels with fibrin thrombi. Livedoid vasculopathy is known to primarily affect the lower extremities. We report the first case of livedoid vasculopathy affecting the penis. A 60-year-old male was evaluated for a split urine stream with associated irritation and peeling of the skin of the glans penis. His penile ulcer continued to enlarge despite steroids and antibiotics. Due to diagnostic uncertainty, a biopsy was performed which revealed hyaline thrombi within the lumens of small vessels within the upper to mid dermis, fibrinoid material in the walls of these blood vessels and within the perivascular stroma with overlying and adjacent epidermal spongiosis, and mild perivascular lymphocytic infiltrate with a few scattered neutrophils most consistent with livedoid vasculitis. He was started on aspirin and pentoxifylline with limited improvement and was later started on apixaban with near-complete resolution in 6 months. Penile livedoid vasculopathy has not been previously reported in the English literature. Early diagnosis and treatment are imperative to limit morbidity.</p>","PeriodicalId":9632,"journal":{"name":"Case Reports in Vascular Medicine","volume":"2023 ","pages":"6920383"},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10335878/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10192802","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Case Reports in Vascular Medicine
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