Pub Date : 2023-07-05DOI: 10.6001/chemija.2023.34.2.3
Milda Liubinienė, Ugnė Urbaitytė, A. Beganskiene
Biological degradation of documentary heritage is a serious issue faced by libraries, museums and archives as it can lead to paper becoming brittle, fragile and discoloured, resulting in a loss of information. This study investigates the impact of didecyldimethylammonium bromide (DDAB) on the properties of pure or inked paper and the growth of different types of fungi. Three fungi species known for their ability to cause paper biodeterioration in libraries and museums, Aspergillus clavatus Desm, Penicillium paneum Frisvald and Ulocladium chartarum Preuss, were selected for the DDAB salt antifungal activity test. The study measured the pH and degree of polymerization (DP), monitored colour changes and conducted scanning electron microscopy analyses (SEM) to confirm that DDAB can be used as a biocide for fungi on pure or inked paper. The study also investigated the antifungal effect of DDAB on paper treated with different types of ink, including black (iron-gall ink) and brown (copper ink). Didecyldimethylammonium bromide (DDAB) can be used as a biocide for cleaning and preserving paper documents, with active concentrations of 0.7 and 1%.
{"title":"Study of the antifungal effects of quaternary ammonium salt for the preservation of inked paper","authors":"Milda Liubinienė, Ugnė Urbaitytė, A. Beganskiene","doi":"10.6001/chemija.2023.34.2.3","DOIUrl":"https://doi.org/10.6001/chemija.2023.34.2.3","url":null,"abstract":"Biological degradation of documentary heritage is a serious issue faced by libraries, museums and archives as it can lead to paper becoming brittle, fragile and discoloured, resulting in a loss of information. This study investigates the impact of didecyldimethylammonium bromide (DDAB) on the properties of pure or inked paper and the growth of different types of fungi. Three fungi species known for their ability to cause paper biodeterioration in libraries and museums, Aspergillus clavatus Desm, Penicillium paneum Frisvald and Ulocladium chartarum Preuss, were selected for the DDAB salt antifungal activity test. The study measured the pH and degree of polymerization (DP), monitored colour changes and conducted scanning electron microscopy analyses (SEM) to confirm that DDAB can be used as a biocide for fungi on pure or inked paper. The study also investigated the antifungal effect of DDAB on paper treated with different types of ink, including black (iron-gall ink) and brown (copper ink). Didecyldimethylammonium bromide (DDAB) can be used as a biocide for cleaning and preserving paper documents, with active concentrations of 0.7 and 1%.","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-07-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45329485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-07DOI: 10.6001/chemija.2023.34.1.1
Vaidas Pudžaitis, M. Talaikis, G. Valinčius, G. Niaura
Tethered bilayer lipid membranes (tBLMs) are versatile platforms for the analysis of biochemical and biophysical processes at biological membranes. To control the stability and functional properties of these artificial constructions, molecular-level knowledge on the organization and structure is required. We used surface-enhanced infrared absorption spectroscopy (SEIRAS) to elucidate the in situ formation of tBLMs on a gold substrate. The alkyl chains of long-chain anchoring thiol in a mixed self-assembled monolayer after 60 min of incubation in an adsorption methanol-d4 solution was found to be in a disordered state. Spectroscopic data revealed the complete formation of a bilayer after 60 min of incubation of a mixed anchoring monolayer in a phosphate buffer solution containing vesicles formed from partially deuterated lipid DPPC-d62 and cholesterol-d7. The temporal evolution of absorption bands from the lipid, anchoring mixed monolayer thiol, and water with increasing the bilayer formation time in the phosphate buffer solution containing vesicles revealed a two-stage process. Firstly, the adsorption of lipid molecules with a simultaneous withdrawal of water takes place at the interface. Secondly, the transformation of alkyl chains of the anchoring monolayer due to the insertion and interaction of lipids with the monolayer proceeds.
{"title":"Formation of tethered bilayer lipid membranes on gold surface probed by in situ SEIRAS","authors":"Vaidas Pudžaitis, M. Talaikis, G. Valinčius, G. Niaura","doi":"10.6001/chemija.2023.34.1.1","DOIUrl":"https://doi.org/10.6001/chemija.2023.34.1.1","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000Tethered bilayer lipid membranes (tBLMs) are versatile platforms for the analysis of biochemical and biophysical processes at biological membranes. To control the stability and functional properties of these artificial constructions, molecular-level knowledge on the organization and structure is required. We used surface-enhanced infrared absorption spectroscopy (SEIRAS) to elucidate the in situ formation of tBLMs on a gold substrate. The alkyl chains of long-chain anchoring thiol in a mixed self-assembled monolayer after 60 min of incubation in an adsorption methanol-d4 solution was found to be in a disordered state. Spectroscopic data revealed the complete formation of a bilayer after 60 min of incubation of a mixed anchoring monolayer in a phosphate buffer solution containing vesicles formed from partially deuterated lipid DPPC-d62 and cholesterol-d7. The temporal evolution of absorption bands from the lipid, anchoring mixed monolayer thiol, and water with increasing the bilayer formation time in the phosphate buffer solution containing vesicles revealed a two-stage process. Firstly, the adsorption of lipid molecules with a simultaneous withdrawal of water takes place at the interface. Secondly, the transformation of alkyl chains of the anchoring monolayer due to the insertion and interaction of lipids with the monolayer proceeds. \u0000 \u0000 \u0000 \u0000","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42339746","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-07DOI: 10.6001/chemija.2023.34.1.5
Gerardas Laurinavičius, Vilius Poškus
Monolithic solid phase microextraction silica sorbent coated with silver nanopar ticles (Ag NPs) was successfully synthesized in a small quartz capillary. The sorbent was tested in a headspace microextraction mode using various aromatic compounds followed by gas chromatography analysis. Due to the π-π electronic interaction between analytes aromatic systems and silver particles immobilized on the sorbent surface, the analytes were successfully extracted from a sample headspace and determined by gas chromatographic analysis.
{"title":"Synthesis and investigation of silver-coated monolithic solid phase microextraction silica sorbent","authors":"Gerardas Laurinavičius, Vilius Poškus","doi":"10.6001/chemija.2023.34.1.5","DOIUrl":"https://doi.org/10.6001/chemija.2023.34.1.5","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000Monolithic solid phase microextraction silica sorbent coated with silver nanopar ticles (Ag NPs) was successfully synthesized in a small quartz capillary. The sorbent was tested in a headspace microextraction mode using various aromatic compounds followed by gas chromatography analysis. Due to the π-π electronic interaction between analytes aromatic systems and silver particles immobilized on the sorbent surface, the analytes were successfully extracted from a sample headspace and determined by gas chromatographic analysis. \u0000 \u0000 \u0000 \u0000","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44402442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-07DOI: 10.6001/chemija.2023.34.1.4
Sukomol Barua, A. Balčiūnaitė, J. Vaičiūnienė, L. Tamašauskaitė-Tamašiūnaitė, E. Norkus
In this study, three-dimensional gold-nickel-molybdenum (Au(NiMo)) catalysts have been studied as catalysts for the oxygen evolution reaction (OER). The catalysts have been deposited on a titanium surface using electroplating and galvanic displacement techniques. The modification of NiMo with a low amount of Au crystallites in a range of 1.2– 5.2 μgAucm–2 results in enhanced activity for OER in the alkaline medium compared to respective binary un-modified NiMo catalysts. The current densities for OER increase ca.1.2–7.3 and 1.3–5.1 times with an increase in temperature from 25 up to 75°C using the prepared 3D binary NiMo/ Ti and Au(NiMo)/Ti catalysts, respectively.
{"title":"Three-dimensional Au(NiMo)/Ti catalysts for efficient oxygen evolution reaction","authors":"Sukomol Barua, A. Balčiūnaitė, J. Vaičiūnienė, L. Tamašauskaitė-Tamašiūnaitė, E. Norkus","doi":"10.6001/chemija.2023.34.1.4","DOIUrl":"https://doi.org/10.6001/chemija.2023.34.1.4","url":null,"abstract":"In this study, three-dimensional gold-nickel-molybdenum (Au(NiMo)) catalysts have been studied as catalysts for the oxygen evolution reaction (OER). The catalysts have been deposited on a titanium surface using electroplating and galvanic displacement techniques. The modification of NiMo with a low amount of Au crystallites in a range of 1.2– 5.2 μgAucm–2 results in enhanced activity for OER in the alkaline medium compared to respective binary un-modified NiMo catalysts. The current densities for OER increase ca.1.2–7.3 and 1.3–5.1 times with an increase in temperature from 25 up to 75°C using the prepared 3D binary NiMo/ Ti and Au(NiMo)/Ti catalysts, respectively.","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47673383","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-07DOI: 10.6001/chemija.2023.34.1.3
A. Kozma, N. Golub, Yevhenii Golub, V. Sidey, A. Solomon, A. Kuznietsova, Y. Herneshii
Copper (II) orthophosphate trihydrate Cu3(PO4)2·3H2O has been synthesized by the exchange chemical reactions in aqueous solutions from the compounds Cu(NO3)2·3H2O, NH4OH and H3PO4. The final product has been investigated by using atomic absorption spectroscopy (AAS), infrared spectrometry (IRS), differential thermal analysis (DTA) and X-ray powder diffraction (XRD) techniques. For the first time, the experimental heat capacity Ср° of Cu3(PO4)2·3H2O has been investigated in the temperature range 198‒402 K. Combining the experimental results with the literature data made it possible to determine the thermodynamic and thermochemical properties, such as enthalpy НТ° , entropy SТ° , Gibbs energy GТ° , enthalpy of formation ΔHf°(T), Gibbs energy of formation ΔGf°(T) and logarithm of the equilibrium constant of formation reaction log[Kf°(T)], for the title compound. It was found that at the extreme temperatures of the experiment, Cu3(PO4)2·3H2O has Ср° = 245.96 J·mol–1·K–1, Н° = –3169.59 kJ·mol–1, S° = 311.34 J·mol–1·K–1, G° = –3231.24 kJ·mol–1 (at 198 K); Ср° = 455.31 J·mol–1·K–1, Н° = –3097.93 kJ·mol–1, S° = 551.48 J·mol–1·K–1, G° = –3319.62 kJ·mol–1, ΔHf° = –3138.48 kJ·mol–1, ΔGf° = –2625.39 kJ·mol–1, log[K ] = 341.13 (at 402 K).
{"title":"Thermodynamic and thermochemical properties of Cu3(PO4)2·3H2O","authors":"A. Kozma, N. Golub, Yevhenii Golub, V. Sidey, A. Solomon, A. Kuznietsova, Y. Herneshii","doi":"10.6001/chemija.2023.34.1.3","DOIUrl":"https://doi.org/10.6001/chemija.2023.34.1.3","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000Copper (II) orthophosphate trihydrate Cu3(PO4)2·3H2O has been synthesized by the exchange chemical reactions in aqueous solutions from the compounds Cu(NO3)2·3H2O, NH4OH and H3PO4. The final product has been investigated by using atomic absorption spectroscopy (AAS), infrared spectrometry (IRS), differential thermal analysis (DTA) and X-ray powder diffraction (XRD) techniques. For the first time, the experimental heat capacity Ср° of Cu3(PO4)2·3H2O has been investigated in the temperature range 198‒402 K. Combining the experimental results with the literature data made it possible to determine the thermodynamic and thermochemical properties, such as enthalpy НТ° , entropy SТ° , Gibbs energy GТ° , enthalpy of formation ΔHf°(T), Gibbs energy of formation ΔGf°(T) and logarithm of the equilibrium constant of formation reaction log[Kf°(T)], for the title compound. It was found that at the extreme temperatures of the experiment, Cu3(PO4)2·3H2O has Ср° = 245.96 J·mol–1·K–1, Н° = –3169.59 kJ·mol–1, S° = 311.34 J·mol–1·K–1, G° = –3231.24 kJ·mol–1 (at 198 K); Ср° = 455.31 J·mol–1·K–1, Н° = –3097.93 kJ·mol–1, S° = 551.48 J·mol–1·K–1, G° = –3319.62 kJ·mol–1, ΔHf° = –3138.48 kJ·mol–1, ΔGf° = –2625.39 kJ·mol–1, log[K ] = 341.13 (at 402 K). \u0000 \u0000 \u0000 \u0000","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48528142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-07DOI: 10.6001/chemija.2023.34.1.7
Birutė Sapijanskaitė-Banevič, Birutė Grybaitė, R. Vaickelionienė, I. Bružaitė
1,3-Thiazole is one of the most attractive cores in heterocycles chemistry and drug discovery. Its widespread use in diverse medicinal substances makes thiazole a versatile scaffold, which leads to the novel generation of efficient pharmaceuticals. This study was intended to synthesize a series of N,N-disubstituted aminothiazole derivatives having various fragments at the 4th and 5th positions of the thiazole ring. The formation of such derivatives was carried out via the Hantsch reaction, condensation reactions with various aldehydes, bromination and formation of the chalcone-type derivatives. Another goal of this study was to investigate the antibacterial properties of the obtained compounds against some gram-positive Bacillus species such as B. coagulans, B. subtilis and B. megaterium and gram-negative Escherichia coli. As it is shown by our studies in recent years, the synthesized thiazoles can serve for future development of potent thiazole derivatives for various medicinal targets.
{"title":"Synthesis, transformation and preliminary bioassay of 3-(thiazol-2-yl(p-tolyl)amino)propanoic acid derivatives","authors":"Birutė Sapijanskaitė-Banevič, Birutė Grybaitė, R. Vaickelionienė, I. Bružaitė","doi":"10.6001/chemija.2023.34.1.7","DOIUrl":"https://doi.org/10.6001/chemija.2023.34.1.7","url":null,"abstract":"\u0000 \u0000 \u0000 \u00001,3-Thiazole is one of the most attractive cores in heterocycles chemistry and drug discovery. Its widespread use in diverse medicinal substances makes thiazole a versatile scaffold, which leads to the novel generation of efficient pharmaceuticals. This study was intended to synthesize a series of N,N-disubstituted aminothiazole derivatives having various fragments at the 4th and 5th positions of the thiazole ring. The formation of such derivatives was carried out via the Hantsch reaction, condensation reactions with various aldehydes, bromination and formation of the chalcone-type derivatives. Another goal of this study was to investigate the antibacterial properties of the obtained compounds against some gram-positive Bacillus species such as B. coagulans, B. subtilis and B. megaterium and gram-negative Escherichia coli. As it is shown by our studies in recent years, the synthesized thiazoles can serve for future development of potent thiazole derivatives for various medicinal targets. \u0000 \u0000 \u0000 \u0000","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45253429","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-07DOI: 10.6001/chemija.2023.34.1.6
S. Saunoriūtė, O. Ragažinskienė, L. Raudonė, L. Ivanauskas, M. Marksa
In the last decade, special attention has been paid to Artemisia (L.) genus plants, the possibilities of using their medicinal raw material for therapeutic purposes. The aim of the research was to determine the variability of the phenolic compounds in the medicinal raw material of four introduced Artemisia L. species and to evaluate the antioxidant activity of extracts in vitro. The highest total amount of phenolic compounds (297.37±9.18 mg RE/g DW) and flavonoids (77.73±7.40 mg RE/g DW) evaluated via spectrophotometry was detected in Artemisia annua L. medicinal raw material samples. Qualitative and quantitative analysis of individual phenolics in the samples of Artemisia extracts was carried out by applying the HPLC method. In the studied extracts, the predominant phenolic compounds were chlorogenic acid and 3,5-dicaffeoylquinic acid. It was determined that the methanol extracts of A. annua medicinal raw material have the strongest antiradical and reducing properties.
{"title":"Phenolic content and antioxidant activity in medicinal raw material of introduced Artemisia L. species in Lithuania","authors":"S. Saunoriūtė, O. Ragažinskienė, L. Raudonė, L. Ivanauskas, M. Marksa","doi":"10.6001/chemija.2023.34.1.6","DOIUrl":"https://doi.org/10.6001/chemija.2023.34.1.6","url":null,"abstract":"\u0000 \u0000 \u0000 \u0000In the last decade, special attention has been paid to Artemisia (L.) genus plants, the possibilities of using their medicinal raw material for therapeutic purposes. The aim of the research was to determine the variability of the phenolic compounds in the medicinal raw material of four introduced Artemisia L. species and to evaluate the antioxidant activity of extracts in vitro. The highest total amount of phenolic compounds (297.37±9.18 mg RE/g DW) and flavonoids (77.73±7.40 mg RE/g DW) evaluated via spectrophotometry was detected in Artemisia annua L. medicinal raw material samples. Qualitative and quantitative analysis of individual phenolics in the samples of Artemisia extracts was carried out by applying the HPLC method. In the studied extracts, the predominant phenolic compounds were chlorogenic acid and 3,5-dicaffeoylquinic acid. It was determined that the methanol extracts of A. annua medicinal raw material have the strongest antiradical and reducing properties. \u0000 \u0000 \u0000 \u0000","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49238347","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-04-07DOI: 10.6001/chemija.2023.34.1.2
R. Mažeikienė, G. Niaura, A. Malinauskas
Raman spectroscopic study of poly(N-methylaniline) as a thin layer deposited at a electrode was performed in an electrochemical system. A broad range of Raman excitation wavelengths from UV (325 nm) through blue (442 nm) and red (633 nm) to NIR (785 nm) were used. Two limiting redox forms, a reduced (leucoemeraldine) and a fully oxidized one, were considered as obtained at controlled electrochemical potential conditions, and two solution pH of 2.0 and 8.0 were selected to ensure the existence of protonated and deprotonated forms. The Raman spectra obtained and discussed show a strong enhancement for the reduced form at UV and blue laser line excitations, whereas the Raman enhancement for an oxidized form was observed for red and NIR laser line excitations. The main Raman features for the combinations of the reduced and oxidized, and protonated or deprotonated states of poly(N-methylaniline) were analyzed and compared.
{"title":"Multiwavelength Raman spectroelectrochemical study of poly(N-methylaniline): An overview","authors":"R. Mažeikienė, G. Niaura, A. Malinauskas","doi":"10.6001/chemija.2023.34.1.2","DOIUrl":"https://doi.org/10.6001/chemija.2023.34.1.2","url":null,"abstract":"\u0000 \u0000 \u0000Raman spectroscopic study of poly(N-methylaniline) as a thin layer deposited at a electrode was performed in an electrochemical system. A broad range of Raman excitation wavelengths from UV (325 nm) through blue (442 nm) and red (633 nm) to NIR (785 nm) were used. Two limiting redox forms, a reduced (leucoemeraldine) and a fully oxidized one, were considered as obtained at controlled electrochemical potential conditions, and two solution pH of 2.0 and 8.0 were selected to ensure the existence of protonated and deprotonated forms. The Raman spectra obtained and discussed show a strong enhancement for the reduced form at UV and blue laser line excitations, whereas the Raman enhancement for an oxidized form was observed for red and NIR laser line excitations. The main Raman features for the combinations of the reduced and oxidized, and protonated or deprotonated states of poly(N-methylaniline) were analyzed and compared. \u0000 \u0000 \u0000","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2023-04-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43282416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-09DOI: 10.6001/chemija.v33i4.4803
Inga Gabriunaite, Eimantas Zolubas, A. Valiūnienė
In this work, we attempted to design phospholipid bilayers tethered to semiconducting metal oxide films. The phospholipid layers assembled on compact monocomponent self-assembled monolayers (SAM) on oxide films were accomplished earlier; however, previous studies indicated a poor ability of these layers to functionally reconstitute transmembrane proteins. Commercially available fluorine doped tin oxide (FTO) sheet glass was chosen as a model solid support. FTO surface was functionalised utilising by the mixture of the long and short chain hydrophobic silanes. Specifically, octadecyltrichlorosilane (OTS) and vinyltrimethoxysilane (VTS) were used to assemble mixed silane-based SAMs on FTO. Exposure of mixed SAMs to a solution of multilamellar vesicles of 1,2-dioleoylsn- glycero-3-phosphocholine (DOPC) and 40% cholesterol triggered the changes of electrochemical parameters commensurate with the formation of additional dielectric layers of phospholipids.
{"title":"Formation of mixed hybrid bilayer lipid membrane on transparent thin film oxide electrodes","authors":"Inga Gabriunaite, Eimantas Zolubas, A. Valiūnienė","doi":"10.6001/chemija.v33i4.4803","DOIUrl":"https://doi.org/10.6001/chemija.v33i4.4803","url":null,"abstract":"In this work, we attempted to design phospholipid bilayers tethered to semiconducting metal oxide films. The phospholipid layers assembled on compact monocomponent self-assembled monolayers (SAM) on oxide films were accomplished earlier; however, previous studies indicated a poor ability of these layers to functionally reconstitute transmembrane proteins. Commercially available fluorine doped tin oxide (FTO) sheet glass was chosen as a model solid support. FTO surface was functionalised utilising by the mixture of the long and short chain hydrophobic silanes. Specifically, octadecyltrichlorosilane (OTS) and vinyltrimethoxysilane (VTS) were used to assemble mixed silane-based SAMs on FTO. Exposure of mixed SAMs to a solution of multilamellar vesicles of 1,2-dioleoylsn- glycero-3-phosphocholine (DOPC) and 40% cholesterol triggered the changes of electrochemical parameters commensurate with the formation of additional dielectric layers of phospholipids.","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44148118","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-12-09DOI: 10.6001/chemija.v33i4.4809
Edvardas Brimas, R. Raudonis, A. Kareiva
Obesity has become a global pandemic, leading to the development of many common disorders, such as type 2 diabetes, metabolic syndrome and cardiovascular diseases, and even increases the risk of several cancers. The adipose tissue of obese patients was characterised as a tissue microenvironment composed of adipose tissue macrophages, precursor and hypertrophic adipocytes, and other immune cells that predominantly produce pro-inflammatory cytokines for chronic, low-grade inflammation. In this study, several analytical techniques, such as gas and liquid chromatography, Fourier transform infrared (FTIR) and Raman spectroscopies, nuclear magnetic resonance (NMR) spectroscopy, scanning electron microscopy (SEM) and elemental analysis, were discussed as the main tools used for the characterisation of adipose tissue samples. The emphasis was focused on the relation between the obtained results which provide information about the chemical and structural composition of adipose tissue layers in the human body, as well as main microstructural features and obesity. It was demonstrated that these methods are indispensable tools in order to investigate some special features of human adipose tissue, identifying chemical composition and structural features. Moreover, the summarised results let us to conclude that such characterisation of adipose tissue is an essential step for the possible prediction of the appearance of symptoms of different diseases.
{"title":"Analytical methods used for the characterisation of specific features of biological tissues related with obesity: A review","authors":"Edvardas Brimas, R. Raudonis, A. Kareiva","doi":"10.6001/chemija.v33i4.4809","DOIUrl":"https://doi.org/10.6001/chemija.v33i4.4809","url":null,"abstract":"Obesity has become a global pandemic, leading to the development of many common disorders, such as type 2 diabetes, metabolic syndrome and cardiovascular diseases, and even increases the risk of several cancers. The adipose tissue of obese patients was characterised as a tissue microenvironment composed of adipose tissue macrophages, precursor and hypertrophic adipocytes, and other immune cells that predominantly produce pro-inflammatory cytokines for chronic, low-grade inflammation. In this study, several analytical techniques, such as gas and liquid chromatography, Fourier transform infrared (FTIR) and Raman spectroscopies, nuclear magnetic resonance (NMR) spectroscopy, scanning electron microscopy (SEM) and elemental analysis, were discussed as the main tools used for the characterisation of adipose tissue samples. The emphasis was focused on the relation between the obtained results which provide information about the chemical and structural composition of adipose tissue layers in the human body, as well as main microstructural features and obesity. It was demonstrated that these methods are indispensable tools in order to investigate some special features of human adipose tissue, identifying chemical composition and structural features. Moreover, the summarised results let us to conclude that such characterisation of adipose tissue is an essential step for the possible prediction of the appearance of symptoms of different diseases.","PeriodicalId":9720,"journal":{"name":"Chemija","volume":" ","pages":""},"PeriodicalIF":0.6,"publicationDate":"2022-12-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44300430","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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