{"title":"Current status of disability in the elderly and its influencing factors","authors":"Shangxin Liu","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.10.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.10.004","url":null,"abstract":"WHO数据显示，全球约15.6%的人口存在不同程度的失能，且随增龄失能率显著升高。，由于各国对老年人失能的评估标准不同，各国老年人失能率差异显著。老年人失能过程中受诸多因素影响，在失能的前期或早期阶段对风险因素进行干预，能减缓甚至逆转内在能力的下降。本文系统介绍了老年人失能的流行病学概况及其影响因素。","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1079-1081"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46461983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-14DOI: 10.3760/CMA.J.ISSN.0254-9026.2019.10.023
Guan Lili, Huan-Huan Wang, Xiuli Zhang, Hongsheng Zhang, Jing Li
Objective To investigate the effects of postoperative analgesia with Dexmedetomidine combined with Sufentanil on pulmonary infection complications and immune function in patients with lung cancer. Methods A total of 200 patients with lung cancer who underwent radical lung cancer in our hospital from July 2014 to June 2018 were randomly divided into the group A(n=100, receiving Sufentanil analgesia)and group B(n=100, receiving Sufentanil combined with Dexmedetomidine analgesia)according to the random number table method.The analgesic effect, pulmonary complication incidence and immune function were compared between the two groups. Results The analgesic and sedative effects were better in the group B than in the group A at 4, 8, 12 and 24 hours after surgery, respectively(P 0.05). The levels of CD3+, CD4+, CD8+ and CD4+ /CD8+ cells were higher in group B than in group A at 1 day after surgery(t=7.419, 7.867, 11.968 and 8.755, P=0.000). Conclusions Postoperative Dexmedetomidine combined with Sufentanil analgesia not only helps to reduce the incidence of pulmonary complications, but also improves the analgesic effect and immune function in patients with lung cancer undergoing radical surgery. Key words: Lung neoplasms; Dexmedetomidine; Sufentanil; Anesthesia and analgesia
目的探讨右美托咪定联合舒芬太尼术后镇痛对肺癌患者肺部感染并发症及免疫功能的影响。方法选取2014年7月至2018年6月在我院接受根治性肺癌治疗的肺癌患者200例，按随机数字表法随机分为A组(n=100，采用舒芬太尼镇痛)和B组(n=100，采用舒芬太尼联合右美托咪定镇痛)。比较两组镇痛效果、肺部并发症发生率及免疫功能。结果B组在术后4、8、12、24 h的镇痛、镇静效果均优于A组(P < 0.05)。B组术后1 d CD3+、CD4+、CD8+及CD4+ /CD8+细胞水平均高于A组(t=7.419、7.867、11.968、8.755,P=0.000)。结论右美托咪定术后联合舒芬太尼镇痛不仅有助于降低肺癌根治性手术患者肺部并发症的发生率，而且能提高患者的镇痛效果和免疫功能。关键词:肺肿瘤;Dexmedetomidine;舒芬太尼;麻醉与镇痛
{"title":"Effects of postoperative analgesia with Dexmedetomidine combined with Sufentanil on the immune function and complications of pulmonary infection in patients with lung cancer","authors":"Guan Lili, Huan-Huan Wang, Xiuli Zhang, Hongsheng Zhang, Jing Li","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.10.023","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.10.023","url":null,"abstract":"Objective \u0000To investigate the effects of postoperative analgesia with Dexmedetomidine combined with Sufentanil on pulmonary infection complications and immune function in patients with lung cancer. \u0000 \u0000 \u0000Methods \u0000A total of 200 patients with lung cancer who underwent radical lung cancer in our hospital from July 2014 to June 2018 were randomly divided into the group A(n=100, receiving Sufentanil analgesia)and group B(n=100, receiving Sufentanil combined with Dexmedetomidine analgesia)according to the random number table method.The analgesic effect, pulmonary complication incidence and immune function were compared between the two groups. \u0000 \u0000 \u0000Results \u0000The analgesic and sedative effects were better in the group B than in the group A at 4, 8, 12 and 24 hours after surgery, respectively(P 0.05). The levels of CD3+, CD4+, CD8+ and CD4+ /CD8+ cells were higher in group B than in group A at 1 day after surgery(t=7.419, 7.867, 11.968 and 8.755, P=0.000). \u0000 \u0000 \u0000Conclusions \u0000Postoperative Dexmedetomidine combined with Sufentanil analgesia not only helps to reduce the incidence of pulmonary complications, but also improves the analgesic effect and immune function in patients with lung cancer undergoing radical surgery. \u0000 \u0000 \u0000Key words: \u0000Lung neoplasms; Dexmedetomidine; Sufentanil; Anesthesia and analgesia","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1158-1161"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48293994","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-10-14DOI: 10.3760/CMA.J.ISSN.0254-9026.2019.10.024
Luo Liuqin, Zhang Mingsheng, Zhang Lei, Pang Wenjun, Bai Wenfang
Objective To investigate the correlations of indexes of isokinetic muscle testing with grip, the circumference of muscle, the time up and go test(TUGT), and the distance of 6-minutes walk test(6MWT). And to identify the availability of isokinetic muscle testing in diagnosing sarcopenia in the elderly. Methods A total of 27 elderly patients with sarcopenia admitted in rehabilitation department of our hospital from Jan.2017 to Dec.2017 were enrolled in this cross-sectional study.Patients were evaluated in many aspects, including comprehensive evaluation by the comprehensive assessment, the skeletal muscle mass detection by dual energy X-Ray absorptiometry, the power of gripping by dynamometer, the circumference of muscle of upper and lower extremities, the muscle strength by isokinetic muscle testing, the sports ability by TUGT and 6MWT. Results Isokinetic muscle testing including the knee flexion, knee extension, elbow extension, wrist extension, TUGT, 6MWT, the power of left gripping, the circumference of left forearm muscle showed a negative correlations to the age(r=-0.54, -0.44, -0.52, -0.61, -0.53, -0.41 and-0.39, P<0.05). A positive correlation were observed between TUGT and the age(r=0.44, P<0.05). The positive correlations between every index in isokinetic muscles testing and the power of both left and right gripping were observed(r=0.66, 0.67, 0.67, 0.67, 0.56, 0.62, 0.54, 0.54, 0.64, 0.59, 0.59 and 0.56, P<0.05). The knee flexion, knee extension, elbow flexion, elbow extension and wrist extension of Isokinetic muscle testing showed a positive correlations to 6MWT(r=0.71, 0.65, 0.62, 0.60 and 0.59, P<0.05). The knee flexion, knee extension, elbow extension and wrist extension of isokinetic muscle testing showed a negative correlations to TUGT(r=-0.57, -0.52, -0.42 and-0.48, P<0.05). Every index of isokinetic muscle testing showed a positive correlations to the circumference of both forearms(r=0.45, 0.47, 0.52, 0.42, 0.41, 0.44, 0.49, 0.52、0.60, 0.54, 0.44 and 049, P<0.05). Conclusions Isokinetic muscle testing can accurately evaluate the changes of muscle strength in the elderly with sarcopenia.It can be considered as the reference index of motor function in diagnosing sarcopenia in the elderly. Key words: Sarcopenia; Muscle strength
{"title":"Clinical significance of isokinetic muscles testing in evaluating and diagnosing sarcopenia in the elderly","authors":"Luo Liuqin, Zhang Mingsheng, Zhang Lei, Pang Wenjun, Bai Wenfang","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.10.024","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.10.024","url":null,"abstract":"Objective \u0000To investigate the correlations of indexes of isokinetic muscle testing with grip, the circumference of muscle, the time up and go test(TUGT), and the distance of 6-minutes walk test(6MWT). And to identify the availability of isokinetic muscle testing in diagnosing sarcopenia in the elderly. \u0000 \u0000 \u0000Methods \u0000A total of 27 elderly patients with sarcopenia admitted in rehabilitation department of our hospital from Jan.2017 to Dec.2017 were enrolled in this cross-sectional study.Patients were evaluated in many aspects, including comprehensive evaluation by the comprehensive assessment, the skeletal muscle mass detection by dual energy X-Ray absorptiometry, the power of gripping by dynamometer, the circumference of muscle of upper and lower extremities, the muscle strength by isokinetic muscle testing, the sports ability by TUGT and 6MWT. \u0000 \u0000 \u0000Results \u0000Isokinetic muscle testing including the knee flexion, knee extension, elbow extension, wrist extension, TUGT, 6MWT, the power of left gripping, the circumference of left forearm muscle showed a negative correlations to the age(r=-0.54, -0.44, -0.52, -0.61, -0.53, -0.41 and-0.39, P<0.05). A positive correlation were observed between TUGT and the age(r=0.44, P<0.05). The positive correlations between every index in isokinetic muscles testing and the power of both left and right gripping were observed(r=0.66, 0.67, 0.67, 0.67, 0.56, 0.62, 0.54, 0.54, 0.64, 0.59, 0.59 and 0.56, P<0.05). The knee flexion, knee extension, elbow flexion, elbow extension and wrist extension of Isokinetic muscle testing showed a positive correlations to 6MWT(r=0.71, 0.65, 0.62, 0.60 and 0.59, P<0.05). The knee flexion, knee extension, elbow extension and wrist extension of isokinetic muscle testing showed a negative correlations to TUGT(r=-0.57, -0.52, -0.42 and-0.48, P<0.05). Every index of isokinetic muscle testing showed a positive correlations to the circumference of both forearms(r=0.45, 0.47, 0.52, 0.42, 0.41, 0.44, 0.49, 0.52、0.60, 0.54, 0.44 and 049, P<0.05). \u0000 \u0000 \u0000Conclusions \u0000Isokinetic muscle testing can accurately evaluate the changes of muscle strength in the elderly with sarcopenia.It can be considered as the reference index of motor function in diagnosing sarcopenia in the elderly. \u0000 \u0000 \u0000Key words: \u0000Sarcopenia; Muscle strength","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1162-1165"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47461810","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Preventing disability among the elderly is a problem that must be faced and valued in the health management of the elderly. In order to vigorously carry out disability health education for the elderly and improve their knowledge and health literacy related to disability, entrusted by the Aging Health Department of the National Health Commission, the National Geriatrics Center and the Geriatrics Branch of the Chinese Medical Association, relying on an expert team, have formulated the "Core Information on Disability Prevention for the Elderly" after multiple expert discussions. The various key knowledge points of the core information are now interpreted.
{"title":"Interpretation of core information on disability prevention for the elderly","authors":"Jing Shi, Chao Gao","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.10.003","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.10.003","url":null,"abstract":"预防老年人失能是老年人健康管理工作中必须面对和重视的一个问题。为大力开展老年人失能健康教育，提高老年人群失能相关知识健康素养，受国家卫生健康委员会老龄健康司委托，国家老年医学中心、中华医学会老年医学分会以专家团队为依托，经多次专家讨论会制订《老年人失能预防核心信息》，现对核心信息各知识要点进行解读。","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1077-1078"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42988446","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The occurrence of disability in the elderly is closely related to sarcopenia. Previous views have suggested that decreased muscle mass is the key cause of disability, but recent studies have shown that the relationship between decreased muscle mass and disability is not significant. The decline in muscle strength and muscle mass is the decisive factor leading to dysfunction in elderly people, and muscle fat infiltration may play a core role. Proper nutrition and active exercise can significantly improve sarcopenia and effectively reverse the occurrence of disability. This article elaborates on the mechanism of disability caused by sarcopenia and the interventions for disability.
{"title":"Sarcopenia and physical disability in the elderly","authors":"Juan Liu","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.10.008","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.10.008","url":null,"abstract":"老年人失能的发生与肌少症密切相关。既往观点认为肌肉量下降是导致失能的关键原因，但近年研究表明，肌肉量下降与失能的关系并不显著，肌肉力量和肌肉质量的下降才是导致老年人功能障碍的决定性因素，这其中肌肉脂肪浸润可能起到了核心作用。恰当的营养和积极的运动可显著改善肌少症，并有效逆转失能的发生。本文对肌少症导致失能的机理及失能的干预进行阐述。","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1091-1093"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49283555","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The prevalence and harm of multiple medication use in the elderly are high, and it is worthy of high clinical attention. The coexistence of multiple diseases in the elderly, multiple medical consultations, failure to stop medication in a timely manner, self purchase of over-the-counter drugs, and prescription waterfall are the reasons for multiple medication use. The main risk factors include elderly age, low body weight, ≥ 6 chronic diseases, 9 types of creatinine clearance rate drugs, daily medication ≥ 12 doses, high-risk drugs, and a history of adverse drug reactions. Multiple medication use in the elderly can increase the incidence and mortality rate of disability in the elderly, It has become a serious global public health problem. This article focuses on the relevant content of multiple medication for the elderly, with the aim of improving the understanding of medical workers on multiple medication for the elderly.
{"title":"Evaluation and intervention of polypharmacy in the elderly","authors":"Zaijin Jian","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.10.010","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.10.010","url":null,"abstract":"老年人多重用药的患病率高、危害大，值得临床高度重视。老年人多病共存、多科就诊、未及时停药、自行购买非处方药和处方瀑布等是导致多重用药的原因，主要危险因素有高龄、低体重、患≥6种慢病、肌酐清除率 9种药物、每天服药≥12剂、高危药物、药物不良反应史等，老年人多重用药会增加老年人失能的发生率和病死率，已成为全球严重的公共卫生问题。本文重点讨论老年人多重用药的相关内容，旨在提高医务工作者对老年人多重用药的认识。","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1097-1100"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43439497","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Malnutrition in the elderly is one of the important factors leading to disability in the elderly. The use of effective nutritional screening and evaluation tools can detect malnutrition and nutritional risks early, and through comprehensive assessment of elderly people, identify relevant risk factors to predict the risk of potential adverse prognosis; Providing appropriate nutritional support such as oral nutritional supplements and team intervention targeting multiple risk factors can effectively reduce the occurrence of adverse events, improve disease prognosis and functional status of the elderly, and improve their quality of life.
{"title":"Malnutrition and disability in the elderly","authors":"Lin Kang","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.10.007","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.10.007","url":null,"abstract":"老年人营养不良是导致老年人失能的重要因素之一。运用有效的营养筛查和评估工具可及早发现营养不良及营养风险，并通过老年人综合评估，寻找相关的危险因素来预测潜在不良预后的风险；采取给予口服营养补充制剂等适当的营养支持以及针对多个风险因素的团队干预可以有效地降低不良事件的发生，改善疾病预后及老年人功能状态，提高老年人的生活质量。","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1088-1090"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43514559","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Comprehensive geriatric assessment and disability in the elderly","authors":"Li Peng","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.10.005","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.10.005","url":null,"abstract":"老年人综合评估是现代老年医学的核心技术之一。对老年人失能情况的评估是老年人综合评估的一项重要内容，但目前尚无国际通用的失能评估金标准。本文对目前在老年人综合评估中常用的失能评估工具做一简要概述。","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1082-1084"},"PeriodicalIF":0.0,"publicationDate":"2019-10-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45196162","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-09-14DOI: 10.3760/CMA.J.ISSN.0254-9026.2019.09.004
Xu Chen, Hong-bo Zhang, Wen Li, Yao Yao, Yunyun Xue, Mei-jia Shen, Liu-wei Zhang, Lichao Sun
Objective To investigate serum level changes of heart-type fatty acid-binding protein(H-FABP)and S100 calcium-binding protein B(S-100B)protein in elderly patients with chronic heart failure and their clinical significance. Methods A total of 160 patients with chronic heart failure treated at our hospital were recruited, and 80 healthy individuals receiving regular check-ups were enrolled as normal controls.Serum levels of H-FABP and S-100B and cardiac function index scores were compared between patients with different cardiac function grades.Correlations of serum H-FABP and S-100B levels with N-terminal pro-B-type natrlure tiepeptide(NT-proBNP)and with cardiac function index scores in heart failure patients were analyzed.The sensitivity, specificity and accuracy of serum H-FABP, S-100B and NT-proBNP for heart failure detection were compared. Results Serum levels of H-FABP, S-100B and NT-proBNP in elderly patients with chronic heart failure were elevated with increased cardiac function grading(F=9.823, 11.573 and 13.056, P=0.013, 0.000 and 0.000), and serum levels of H-FABP, S-100B and NT-proBNP were higher in elderly patients with heart failure than in the control group(P<0.05). Serum levels of H-FABP and S-100B were positively correlated with serum NT-proBNP levels, cardiac function grading and left ventricular end-diastolic diameter(LVEDd)(r=0.527, 0.510 and 0.487, P=0.008, 0.003 and 0.002; r=0.604, 0.496 and 0.533, P=0.006, 0.005 and 0.003), and were negatively correlated with left ventricular ejection fraction(LVEF)(r=-0.536 and-0.528, P=0.005 and 0.008). The sensitivity, specificity and accuracy of serum H-FABP combined with S-100B for heart failure detection were 93.2%, 91.6% and 95.7%, respectively. Conclusions Serum levels of H-FABP and S-100B are high in elderly patients with heart failure, and they are correlated with serum NT-proBNP levels, cardiac function grading and LVEDd.H-FABP combined with S-100B has a high positive rate for heart failure detection. Key words: Heart failure; Fatty acid-binding proteins; Calcium-binding proteins
{"title":"Clinical significance of serum level changes of heart-type fatty acid-binding protein and S-100B protein in elderly patients with chronic heart failure","authors":"Xu Chen, Hong-bo Zhang, Wen Li, Yao Yao, Yunyun Xue, Mei-jia Shen, Liu-wei Zhang, Lichao Sun","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.09.004","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.09.004","url":null,"abstract":"Objective \u0000To investigate serum level changes of heart-type fatty acid-binding protein(H-FABP)and S100 calcium-binding protein B(S-100B)protein in elderly patients with chronic heart failure and their clinical significance. \u0000 \u0000 \u0000Methods \u0000A total of 160 patients with chronic heart failure treated at our hospital were recruited, and 80 healthy individuals receiving regular check-ups were enrolled as normal controls.Serum levels of H-FABP and S-100B and cardiac function index scores were compared between patients with different cardiac function grades.Correlations of serum H-FABP and S-100B levels with N-terminal pro-B-type natrlure tiepeptide(NT-proBNP)and with cardiac function index scores in heart failure patients were analyzed.The sensitivity, specificity and accuracy of serum H-FABP, S-100B and NT-proBNP for heart failure detection were compared. \u0000 \u0000 \u0000Results \u0000Serum levels of H-FABP, S-100B and NT-proBNP in elderly patients with chronic heart failure were elevated with increased cardiac function grading(F=9.823, 11.573 and 13.056, P=0.013, 0.000 and 0.000), and serum levels of H-FABP, S-100B and NT-proBNP were higher in elderly patients with heart failure than in the control group(P<0.05). Serum levels of H-FABP and S-100B were positively correlated with serum NT-proBNP levels, cardiac function grading and left ventricular end-diastolic diameter(LVEDd)(r=0.527, 0.510 and 0.487, P=0.008, 0.003 and 0.002; r=0.604, 0.496 and 0.533, P=0.006, 0.005 and 0.003), and were negatively correlated with left ventricular ejection fraction(LVEF)(r=-0.536 and-0.528, P=0.005 and 0.008). The sensitivity, specificity and accuracy of serum H-FABP combined with S-100B for heart failure detection were 93.2%, 91.6% and 95.7%, respectively. \u0000 \u0000 \u0000Conclusions \u0000Serum levels of H-FABP and S-100B are high in elderly patients with heart failure, and they are correlated with serum NT-proBNP levels, cardiac function grading and LVEDd.H-FABP combined with S-100B has a high positive rate for heart failure detection. \u0000 \u0000 \u0000Key words: \u0000Heart failure; Fatty acid-binding proteins; Calcium-binding proteins","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"971-975"},"PeriodicalIF":0.0,"publicationDate":"2019-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49454122","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
In recent years, Klebsiella pneumoniae infection in China has shown an increasing trend, which can cause liver abscess, spleen abscess, joint abscess, as well as endophthalmitis and meningitis. This article reports a case of metastatic infection caused by Klebsiella pneumoniae in an elderly patient with lumbar muscle abscess. When sensitive antibiotics cannot control Klebsiella pneumoniae infection in clinical practice, it is necessary to be vigilant about the possibility of migratory lesions caused by systemic infection, and timely systemic assessment should be conducted to actively identify new infections.
{"title":"Psoas abscess caused by Klebsiella pneumoniae: report of one case","authors":"C. Gong, Jie Wang, H. Mao, Cheng Hang, Jianxin Zhu","doi":"10.3760/CMA.J.ISSN.0254-9026.2019.09.027","DOIUrl":"https://doi.org/10.3760/CMA.J.ISSN.0254-9026.2019.09.027","url":null,"abstract":"近年国内肺炎克雷伯菌感染呈上升趋势，其可引起肝脓肿、脾脓肿、关节脓肿以及眼内炎和脑膜炎等。本文报道肺炎克雷伯菌发生转移性感染引起老年患者腰大肌脓肿一例。临床上在使用敏感抗生素无法控制肺炎克雷伯菌感染时，需警惕全身性感染所致迁徙性病灶可能，应及时行全身评估，积极排查新发感染灶。","PeriodicalId":9997,"journal":{"name":"中华老年医学杂志","volume":"38 1","pages":"1066-1067"},"PeriodicalIF":0.0,"publicationDate":"2019-09-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47517987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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