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Assessment of bone marrow edema on dual-energy CT scans in people with diabetes mellitus and suspected Charcot neuro-osteoarthropathy. 通过双能 CT 扫描评估糖尿病和疑似 Charcot 神经骨关节病患者的骨髓水肿。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-06-04 DOI: 10.1007/s00256-024-04714-3
Carlijn M B Bouman, Marieke A Mens, Ruud H H Wellenberg, Geert J Streekstra, Sicco A Bus, Tessa E Busch-Westbroek, Max Nieuwdorp, Mario Maas

Objective: This study aimed to quantitatively assess the diagnostic value of bone marrow edema (BME) detection on virtual non-calcium (VNCa) images calculated from dual-energy CT (DECT) in people with diabetes mellitus and suspected Charcot neuro-osteoarthropathy (CN).

Materials and methods: People with diabetes mellitus and suspected CN who underwent DECT of the feet (80kVp/Sn150kVp) were included retrospectively. Two blinded observers independently measured CT values on VNCa images using circular regions of interest in five locations in the midfoot (cuneiforms, cuboid and navicular) and the calcaneus of the contralateral or (if one foot was available) the ipsilateral foot. Two clinical groups were formed, one with active CN and one without active CN (no-CN), based on the clinical diagnosis.

Results: Thirty-two people with diabetes mellitus and suspected CN were included. Eleven had clinically active CN. The mean CT value in the midfoot was significantly higher in the CN group (-55.6 ± 18.7 HU) compared to the no-CN group (-94.4 ± 23.5 HU; p < 0.001). In the CN group, the difference in CT value between the midfoot and calcaneus was statistically significant (p = 0.003); this was not the case in the no-CN group (p = 0.357). The overall observer agreement was good for the midfoot (ICC = 0.804) and moderate for the calcaneus (ICC = 0.712). Sensitivity was 100.0% and specificity was 71.4% using a cutoff value of -87.6 HU.

Conclusion: The detection of BME on VNCa images has a potential value in people with diabetes mellitus and suspected active CN.

研究目的本研究旨在定量评估双能 CT(DECT)计算出的虚拟非钙(VNCa)图像上骨髓水肿(BME)检测对糖尿病和疑似 Charcot 神经骨关节病(CN)患者的诊断价值:回顾性纳入接受足部 DECT(80kVp/Sn150kVp)检查的糖尿病和疑似 CN 患者。两名盲人观察者使用脚中部(楔形、立方体和舟骨)和对侧或(如果有一只脚)同侧脚的小方块五个位置的圆形感兴趣区,独立测量 VNCa 图像上的 CT 值。根据临床诊断结果分成两个临床组,一个是有活动性 CN,另一个是无活动性 CN(无 CN):结果:共纳入 32 名疑似 CN 的糖尿病患者。其中 11 人有临床活动性 CN。与无 CN 组(-94.4 ± 23.5 HU; p)相比,CN 组足中部的平均 CT 值(-55.6 ± 18.7 HU)明显较高:在 VNCa 图像上检测 BME 对糖尿病和疑似活动性 CN 患者具有潜在价值。
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引用次数: 0
Mentorship in academic musculoskeletal radiology: perspectives from a junior faculty member. 肌肉骨骼放射学学术领域的导师制:一名青年教师的观点。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-05-07 DOI: 10.1007/s00256-024-04685-5
Samer Soussahn, Yoav Morag, Kara Gaetke-Udager

The first years of an academic musculoskeletal (MSK) faculty position are a time of transition for the junior faculty member, who must rapidly adjust to new clinical, academic, operational, and professional responsibilities. Mentoring has a critical role in helping the faculty member to thrive in these early years. Establishing clear communication, trust, and expectations can set the foundation for an effective mentoring relationship. Junior faculty members ideally would have multiple mentors with different areas of expertise, including mentors of all roles in MSK radiology but also in other radiology divisions and other departments. Private practice MSK radiologists can also benefit from mentorship. Barriers to mentoring in MSK radiology include overall smaller division sizes, a newer and smaller field on a national level, and the increase in clinical volume and remote work that results in less face-to-face interaction. Despite the challenges, both junior MSK faculty members and their mentors can benefit greatly from strong mentoring connections.

担任肌肉骨骼(MSK)学术教职的最初几年是初级教员的过渡时期,他们必须迅速适应新的临床、学术、业务和专业职责。指导在帮助教职员工在最初几年茁壮成长方面发挥着至关重要的作用。建立明确的沟通、信任和期望可以为有效的指导关系奠定基础。青年教师最好能有多个不同专业领域的导师,包括MSK放射科所有角色的导师,以及其他放射科和其他部门的导师。私人执业的 MSK 放射科医师也能从导师制中受益。MSK 放射科导师制面临的障碍包括:科室规模总体较小;在全国范围内,该领域较新且规模较小;临床工作量增加以及远程工作导致面对面交流较少。尽管存在这些挑战,但 MSK 初级教员和他们的导师都能从强大的指导关系中受益匪浅。
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引用次数: 0
A 40-year-old female with swelling in left lower back. 一名 40 岁女性,左腰部肿胀。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-05-22 DOI: 10.1007/s00256-024-04711-6
Sonal Saran, Ravi Hari Phulware
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引用次数: 0
Single slice MR image estimation of 3D supraspinatus intramuscular fatty infiltration in older adults: relevance for clinical practice and research. 老年人冈上肌肌内脂肪浸润的三维单片 MR 图像估算:对临床实践和研究的意义。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-05-23 DOI: 10.1007/s00256-024-04706-3
Ranyah Almardawi, Leopoldo Garcia Zapata, Ramnik Gill, Jacqueline Addona, Irina Kapustina, Sagheer R Ahmed, Kimia Kani, Derik L Davis

Objective: (1) To compare older adults stratified by supraspinatus tendon tear status (STT status)-no tear (Intact), partial-thickness (PT) tear, full-thickness (FT) tear-by 3D Dixon fat fraction (3D-FF); 2D fat fraction (2D-FF); and 2D Goutallier grade (2D-GG) at the Y-shaped view, and 1.4 cm and 2.8 cm medial to the Y-shaped view. Stratified by STT status to determine (2) correlation of 3D-FF with 2D-FF and 2D-GG and (3) inter-rater reliability at and medial to the Y-shaped view.

Materials and methods: Forty-five volunteers ≥ 60 years recruited prospectively received shoulder MRI. 3D-FF and 2D-FF were measured on 6-point-Dixon MRI by three trainees. Goutallier grade was assessed on T1-weighted MRI by three fellowship-trained diagnostic radiologists. Descriptive, reliability, and correlation analyses were performed.

Results: Groups showed no difference in age. The FT group showed higher (p < 0.05) mean 3D-FF (14.09% ± 10.99%), mean 2D-FF (1.4 cm medial to Y-shaped view, 14.91% ± 12.11%; 2.8 cm medial to Y-shaped view, 13.32% ± 9.48%), and mean 2D-GG (Y-shaped view, 1.71 ± 0.78; 1.4 cm medial to Y-shaped view, 1.71 ± 0.69; 2.8 cm medial to Y-shaped view, 1.71 ± 0.72), relative to Intact/PT groups. 3D-FF showed strong correlation with 2D-FF among all groups/all analyses (rho, 0.80-0.98; p < 0.001). 3D-FF showed strong correlation with 2D-GG for all FT group analyses (rho, 0.85-0.91; p < 0.05). 3D-FF showed moderate-to-strong correlation considering all Intact/PT group analyses (rho, 0.51-0.79; p < 0.50). Dixon fat fraction showed excellent reliability for all groups (≥ 0.884, intraclass correlation coefficient). Goutallier grade showed excellent reliability for FT group (0.771, weighted Fleiss's kappa) but poor (0.294) and fair (0.502) for Intact and PT groups, respectively.

Conclusion: Single slice MR image estimation of 3D supraspinatus intramuscular fatty infiltration has merit for continued use in clinical populations requiring potential rotator-cuff-repair surgery. However, Dixon fat fraction should be prioritized for use in research over Goutallier grade due to superior reliability.

目的:(1) 根据冈上肌腱撕裂状态(STT 状态)--无撕裂(完好无损)、部分厚度撕裂(PT)、全厚撕裂(FT)--对老年人进行分层,在 Y 型切面、Y 型切面内侧 1.4 厘米和 2.8 厘米处通过三维 Dixon 脂肪分数(3D-FF)、二维脂肪分数(2D-FF)和二维 Goutallier 等级(2D-GG)进行比较。根据 STT 状态进行分层,以确定 (2) 3D-FF 与 2D-FF 和 2D-GG 的相关性,以及 (3) Y 型切面和 Y 型切面内侧的评分者之间的可靠性:前瞻性招募的 45 名年龄≥ 60 岁的志愿者接受了肩部 MRI 检查。由三名受训者在 6 点-Dixon MRI 上测量三维-FF 和二维-FF。三名受过研究培训的放射诊断医师在 T1 加权磁共振成像上对 Goutallier 等级进行评估。对结果进行了描述性、可靠性和相关性分析:结果:各组在年龄上没有差异。结果显示:各组在年龄上无差异,FT 组显示出更高的年龄(P三维冈上肌内脂肪浸润的单切片 MR 图像估算值得在可能需要进行肩袖修复手术的临床人群中继续使用。不过,由于 Dixon 脂肪分数比 Goutallier 等级更可靠,在研究中应优先使用 Dixon 脂肪分数。
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引用次数: 0
Direct MR arthrography without image guidance: a practical guide, joint-by-joint. 无图像引导的直接磁共振关节造影:逐个关节的实用指南。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-05-27 DOI: 10.1007/s00256-024-04709-0
Roque Oca Pernas, Guillermo Fernández Cantón

Direct MR arthrography (dMRA) is a fundamental technique in diagnosing pathology in major peripheral joints, allowing for precise evaluation of intra-articular structures. Although injection guidance is typically performed using imaging techniques such as ultrasound or fluoroscopy, puncture via anatomical landmarks may be useful in certain circumstances where it has been proven to be a safe and effective procedure. This paper describes the indications and injection technique of dMRA, joint by joint, focusing on the different technical details, from the most common locations, like the shoulder or hip, to those with more restricted clinical indications, such as the wrist, knee, elbow, or ankle. The most relevant anatomical landmarks are detailed for each joint, aiding in the intra-articular introduction of diluted contrast, highlighting the most accessible trajectories and structures to avoid when inserting the needle. Additionally, tips are provided to facilitate proper joint distension. With all this information, this paper aims to serve as a suitable reference guide for performing dMRA without image guidance if needed.

直接磁共振关节造影(dMRA)是诊断主要外周关节病变的基本技术,可对关节内结构进行精确评估。虽然通常使用超声波或透视等成像技术进行注射引导,但在某些情况下,通过解剖标志物进行穿刺可能是一种安全有效的方法。本文逐个关节介绍了 dMRA 的适应症和注射技术,重点是不同的技术细节,从肩关节或髋关节等最常见的部位,到腕关节、膝关节、肘关节或踝关节等临床适应症较为有限的部位。详细介绍了每个关节最相关的解剖标志,有助于在关节内导入稀释的造影剂,强调了最容易进入的轨迹和进针时应避免的结构。此外,本文还提供了一些小贴士,以帮助正确扩张关节。本文提供了所有这些信息,旨在为必要时在无图像引导的情况下进行 dMRA 提供合适的参考指南。
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引用次数: 0
A 40-year-old female with swelling in left lower back. 一名 40 岁女性,左腰部肿胀。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-05-24 DOI: 10.1007/s00256-024-04710-7
Sonal Saran, Ravi Hari Phulware
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引用次数: 0
Abdominal muscle mass. 腹部肌肉质量。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-05-27 DOI: 10.1007/s00256-024-04712-5
Thomas Saliba, Sanjiva Pather, Karim Abdelkafi
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引用次数: 0
Question: Painful right hip. 问题右髋关节疼痛。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-06-25 DOI: 10.1007/s00256-024-04729-w
Amar Nitin Kanani, Rajesh Botchu, Robert Henderson, Kapil Shirodkar
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引用次数: 0
Associations of cumulative voriconazole dose, treatment duration, and alkaline phosphatase with voriconazole-induced periostitis. 伏立康唑累积剂量、治疗时间和碱性磷酸酶与伏立康唑诱发的骨膜炎的关系。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-05-17 DOI: 10.1007/s00256-024-04707-2
Walid Ashmeik, Silvia Schirò, Gabby B Joseph, Thomas M Link

Objective: To investigate the associations of cumulative voriconazole dose, treatment duration, and alkaline phosphatase with voriconazole-induced periostitis.

Materials and methods: One hundred and thirty-one patients with voriconazole use were identified using a clinical informatics tool. Health record data including age, sex, immune status, alkaline phosphatase, voriconazole levels, voriconazole dose, frequency, and treatment duration were collected. Imaging studies during the duration of treatment were reviewed by two radiology trainees and imaging features of voriconazole-induced periostitis were confirmed by a board-certified musculoskeletal radiologist. The length, location in the body, location in the bone, type, and morphology of periostitis lesions were recorded. Incident voriconazole-induced periostitis was defined as new periostitis on imaging after 28 days or more of voriconazole treatment in the absence of an alternative diagnosis. Univariate Firth's logistic regression models were performed using cumulative voriconazole dose, treatment duration, and average ALP as predictors and incident VIP as the outcome.

Results: There were nine patients with voriconazole-induced periostitis and 122 patients without voriconazole-induced periostitis. The most common lesion location in the body was the ribs (37%) and morphology was solid (44%). A 31.5-g increase in cumulative voriconazole dose was associated with 8% higher odds of incident periostitis. Increased treatment duration (63 days) and higher average alkaline phosphatase (50 IU/L) were associated with 7% higher odds of periostitis and 34% higher odds of periostitis, respectively.

Conclusion: Increased cumulative voriconazole dose, treatment duration, and average alkaline phosphatase were associated with higher odds of voriconazole-induced periostitis.

目的研究伏立康唑累积剂量、治疗时间和碱性磷酸酶与伏立康唑诱发的骨膜炎之间的关系:使用临床信息学工具识别了131名使用伏立康唑的患者。收集的健康记录数据包括年龄、性别、免疫状态、碱性磷酸酶、伏立康唑水平、伏立康唑剂量、频率和治疗持续时间。治疗期间的影像学检查由两名放射科见习医师审查,伏立康唑诱发的骨膜炎的影像学特征由一名获得医学会认证的肌肉骨骼放射科医师确认。骨膜炎病变的长度、在体内的位置、在骨内的位置、类型和形态均有记录。伏立康唑诱发的骨膜炎是指在接受伏立康唑治疗 28 天或更长时间后,在没有其他诊断的情况下,通过影像学检查发现新的骨膜炎。以伏立康唑累积剂量、治疗时间和平均 ALP 为预测因素,以事件 VIP 为结果,建立了单变量 Firth Logistic 回归模型:结果:9 名患者患有伏立康唑诱发的骨膜炎,122 名患者未患有伏立康唑诱发的骨膜炎。最常见的病变部位是肋骨(37%),形态为实心(44%)。伏立康唑累积剂量每增加 31.5 克,发生骨膜炎的几率就会增加 8%。治疗时间延长(63 天)和平均碱性磷酸酶升高(50 IU/L)分别与骨膜炎发生几率增加 7% 和 34% 相关:结论:伏立康唑累积剂量、治疗时间和平均碱性磷酸酶的增加与伏立康唑诱发骨膜炎的几率增加有关。
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引用次数: 0
MR imaging signs of shoulder adhesive capsulitis: analysis of potential differentials and improved diagnostic criteria. 肩关节粘连性囊炎的 MR 成像征象:潜在鉴别分析和改进诊断标准。
IF 16.4 1区 化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Pub Date : 2026-01-01 Epub Date: 2024-05-22 DOI: 10.1007/s00256-024-04677-5
Thibault Dupont, Malik Ait Idir, Gabriela Hossu, François Sirveaux, Romain Gillet, Alain Blum, Pedro Augusto Gondim Teixeira

Objective: To evaluate the prevalence of shoulder adhesive capsulitis (AC) signs on MR studies of patients with various common shoulder conditions.

Methods: MR images of 316 patients were retrospectively evaluated. Patients were divided into three groups: controls (66 patients), clinical AC (63 patients), and study group (187 patients). The final diagnosis of AC was reached clinically. The study group was composed of patients with focal and massive rotator cuff tears, active hydroxyapatite deposition disease, fractures around the shoulder, and post-surgery. The following AC signs were evaluated: inferior glenohumeral ligament (IGHL) thickening; coracohumeral ligament (CHL) thickening; and hyperintensity of the inferior glenohumeral ligament, which was graded in four classes.

Results: The IGHL signal intensity was statistically higher in patients with fractures than in controls (P = 0.008). There was no statistically significant difference in IGHL signal between the AC group and patients with massive rotator cuff tears and active hydroxyapatite deposition disease (P > 0.1). IGHL thickness in patients with fractures, massive rotator ruptures, and active hydroxyapatite deposition disease was significantly higher compared to controls (P < 0.02) and significantly lower compared to the AC group (P < 0.0001). Based on these findings, a grading system for fibro-inflammatory capsular changes is proposed.

Conclusion: MR AC signs are frequent in patients with shoulder conditions other than AC; however, in these patients, capsular changes are less prominent than in patients with clinical AC.

目的评估各种常见肩部疾病患者的磁共振检查中肩关节粘连性囊炎(AC)体征的发生率:对 316 名患者的 MR 图像进行回顾性评估。患者分为三组:对照组(66 例)、临床 AC 组(63 例)和研究组(187 例)。AC 的最终诊断由临床得出。研究组由肩袖局灶性撕裂和大面积撕裂、活动性羟基磷灰石沉积症、肩周骨折和手术后的患者组成。对以下交流征象进行了评估:下盂肱韧带(IGHL)增厚;冠肱韧带(CHL)增厚;下盂肱韧带高强度,分为四个等级:骨折患者的 IGHL 信号强度在统计学上高于对照组(P = 0.008)。交流组与肩袖大面积撕裂和活动性羟基磷灰石沉积疾病患者的 IGHL 信号差异无统计学意义(P > 0.1)。与对照组相比,骨折、肩袖大面积断裂和活动性羟基磷灰石沉积疾病患者的 IGHL 厚度明显更高(P 结论:IGHL 厚度的差异在统计学上并不明显:肩关节疾病以外的其他肩部疾病患者经常出现 MR AC 征象,但与临床 AC 患者相比,这些患者的关节囊变化并不明显。
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引用次数: 0
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