Advances in Oral and Maxillofacial Surgery最新文献

英文中文

Autotransplantation of impacted maxillary canines: A conservative surgical-orthodontic strategy – A case report 上颌埋伏牙自体移植：一种保守的手术-正畸策略- 1例报告

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-12-01 Epub Date: 2025-07-29 DOI: 10.1016/j.adoms.2025.100562

D. Sarfi, L. Bouchghel, A. Traore, M. Khazana, F. Bourzgui, I. Ben Yahya

Impaction of maxillary canines is a common dental anomaly. Its management is multidisciplinary and requires both surgical and orthodontic expertise, along with a well-reasoned and appropriate treatment plan. The aim of this study is to report the management of an impacted canine treated within the Department of Oral Surgery at the Center for Dental Consultations and Treatments in Casablanca, Morocco.

Case report

This paper presents the surgical and orthodontic management of a 17-year-old Moroccan female patient with a complete impaction and transposition of tooth 23, associated with the impaction of tooth 21. Several treatment options were considered, among which autotransplantation of tooth 23 was deemed the most appropriate, with the goal of improving facial aesthetics and restoring functional occlusion.

Discussion

Ortho-surgical repositioning of the impacted tooth is the most commonly desired and performed treatment. However, alternative approaches such as autotransplantation can be a valuable solution in certain clinical situations. Given the complexity of the case and the patient's socioeconomic background, autotransplantation represented the most effective option to restore both aesthetics and function.

Conclusion

A thorough assessment of all aspects of the anomaly at the outset of treatment serves as a crucial guide in choosing the most suitable therapeutic approach. Autotransplantation techniques aim to preserve as much alveolar bone volume as possible, thereby optimizing future conditions for implant placement if needed.

上颌犬齿嵌塞是一种常见的牙齿异常。其管理是多学科的，需要外科和正畸专业知识，以及合理和适当的治疗计划。本研究的目的是报告在摩洛哥卡萨布兰卡牙科咨询和治疗中心口腔外科治疗的影响犬的管理。病例报告：本文介绍了一名17岁摩洛哥女性患者的手术和正畸治疗，该患者的牙齿23完全嵌塞和转位，并伴有牙齿21的嵌塞。考虑了几种治疗方案，其中自牙移植23被认为是最合适的，目的是改善面部美观和恢复功能性咬合。矫形手术复位阻生牙是最常见的治疗方法。然而，在某些临床情况下，自体移植等替代方法可能是一种有价值的解决方案。考虑到病例的复杂性和患者的社会经济背景，自体移植是恢复美观和功能的最有效选择。结论在治疗开始时对畸形的各方面进行全面评估是选择最合适的治疗方法的重要指导。自体移植技术的目的是尽可能多地保留牙槽骨体积，从而在需要时优化未来种植体放置的条件。

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引用次数: 0

Giant expansive mass in the maxillary sinus 上颌窦内有巨大肿物

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-12-01 Epub Date: 2025-10-27 DOI: 10.1016/j.adoms.2025.100599

Eliandro de Souza Freitas , Tiago Novaes Pinheiro , Carolina Silvano Vilarinho da Silva , Isabelle Dutra de Castro , Bianca Faria de Lima

Proliferating Trichilemmal Cyst (PTC) is a benign follicular tumor. We describe a 32-year-old male with progressive nasal obstruction, recurrent epistaxis, and periorbital swelling. Imaging revealed a soft-tissue mass with orbital extension, initially suggestive of a vascular lesion. Histopathology and immunohistochemistry confirmed PTC with mural vascular malformation. This case represents the first reported case of PTC in the maxillary sinus, underscoring the importance of considering PTC in the differential diagnosis of sinonasal tumors.

增殖性毛管囊肿是一种良性滤泡性肿瘤。我们描述了一个32岁的男性进行性鼻塞，复发性鼻出血，和眶周肿胀。影像学显示软组织肿块伴眼眶扩张，初步提示血管病变。组织病理学和免疫组化证实PTC伴壁血管畸形。本病例为上颌窦PTC的首例报道，强调了在鼻窦肿瘤鉴别诊断中考虑PTC的重要性。

引用次数: 0

Extensive pyogenic granuloma in a pregnant woman 孕妇广泛的化脓性肉芽肿

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-12-01 Epub Date: 2025-07-30 DOI: 10.1016/j.adoms.2025.100563

Sarfi Dounia , Ben Yahya Ihssane

Introduction

Pregnancy epulis, or pregnancy-associated pyogenic granuloma, is a benign oral tumor linked to hormonal changes and local irritative factors. It typically appears as an exuberant, bleeding, and sometimes painful gingival mass.

Clinical case

We report the case of a 32-year-old woman in her third trimester of pregnancy, presenting with a bilobed tumor evolving over six months, bleeding upon contact. Clinical examination revealed a pedunculated, dark red lesion on the anterior maxillary marginal gingiva. Surgical excision was performed after local debridement. Histology confirmed a pyogenic granuloma. The postoperative course was favorable, with no recurrence until delivery.

Discussion conclusion

This case illustrates the classic features of pregnancy epulis. Proper management allows complete healing without recurrence.

妊娠脓肿或妊娠相关化脓性肉芽肿是一种与激素变化和局部刺激因素有关的良性口腔肿瘤。它通常表现为旺盛，出血，有时疼痛的牙龈肿块。临床病例我们报告的情况下，一个32岁的妇女在她的妊娠晚期，提出了一个发展超过六个月的双叶肿瘤，出血接触。临床检查发现上颌前龈边缘有带梗的暗红色病变。局部清创后行手术切除。组织学证实为化脓性肉芽肿。术后过程良好，分娩前无复发。结论本病例是妊娠性瞳孔的典型特征。适当的治疗可以完全愈合而不会复发。

引用次数: 0

Prevalence of oral mucositis induced by cancer chemotherapy at Yaounde General Hospital 雅温得总医院肿瘤化疗所致口腔黏膜炎患病率调查

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-12-01 Epub Date: 2025-09-23 DOI: 10.1016/j.adoms.2025.100585

Dieudonne Banguen , Paul Ndom , Etienne Atenguena Okobaleba

引用次数: 0

Progressive maxillofacial osteo-condensation revealing a de NOVO mutation of the SATB2 gene in a young woman 进行性颌面骨凝结揭示了年轻女性SATB2基因的从头突变

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-12-01 Epub Date: 2025-10-21 DOI: 10.1016/j.adoms.2025.100596

Berete Pornan Issa Jules , Ferri Joel

SATB2-associated syndrome (SAS) is a rare genetic dysmorphic syndrome. The mechanism of haploinsufficiency of the SATB2 gene, located at 2q32-q33, is thought to be responsible for pathogenic variants. This study aims to present the clinical phenotype and maxillofacial management of a patient carrying a de novo mutation of the SATB2 gene.

We present the case of a patient with a de novo heterozygous pathogenic variant of the SATB2 gene, who presented with intellectual disability without radiological brain abnormalities associated with cleft palate, retrognathia and microstomia, dental abnormalities without dactylological abnormalities. High maxillomandibular bone density was observed. It is an exceptional report because of the progressive densification of the bine. This case broadens the phenotypic spectrum of clinical abnormalities associated with the SATB2 gene. It also highlights the importance of genetic analysis in complex craniofacial malformations.

satb2相关综合征（SAS）是一种罕见的遗传性畸形综合征。位于2q32-q33的SATB2基因的单倍不足机制被认为是致病变异的原因。本研究旨在介绍一名携带SATB2基因新生突变的患者的临床表型和颌面治疗。我们报告了一例SATB2基因新发杂合致病性变异的患者，他表现为智力残疾，但没有与腭裂、颌后畸形和小口畸形相关的放射学脑异常，牙齿异常但没有指趾学异常。上颌下颌骨密度高。这是一个特殊的报告，因为进展致密化的茎。该病例拓宽了与SATB2基因相关的临床异常的表型谱。它也强调了遗传分析在复杂颅面畸形的重要性。

引用次数: 0

Effect of Locally injected PRP on RANKL and OPG in gingival fluid during orthodontic tooth movement: A Canine Model Study 局部注射PRP对正畸牙齿移动时龈液中RANKL和OPG影响的模型研究

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-12-01 Epub Date: 2025-09-19 DOI: 10.1016/j.adoms.2025.100583

Aida Jafari , Shirin Zahra Farhad , Nasim Esnaashari , Sepehr Kobravi , Hossein Jafari

Aims

Blood platelet-rich plasma (PRP) contains a variety of biologically active components, including growth factors. The objective of this study was to examine the effects of topical PRP injection on osteoprotegerin (OPG) and receptor activator of nuclear factor kappa-B ligand (RANKL) mediator levels in the gingival groove fluid of dogs with orthodontic treatment.

Methods

In this study, six adult male dogs, 10–12 months of age, were included. Every dog was randomly assigned to either an experimental or a control group by injecting thrombin-CaCl2 and PRP into one side (experimental group) and thrombin-CaCl2 and a placebo into the opposite side (control group). During the experiment, a maxillary quadrant on one side was assigned as the experimental group and the opposing side as the control group. Maxillary first premolars were bilaterally extracted, followed by the placement of a titanium nickel spring (200 g) between the second premolar and the canine. A mixture of PRP and CaCl2-thrombin was administered to the experimental group on days 1, 21, and 42, whereas the control group received CaCl2-thrombin mixed with a placebo. Samples of gingival groove fluid were collected regularly during the study (on days 0, 1, 2, 7, 21, 42, and 63). A RANKL and OPG enzyme-linked immunosorbent assay was performed to measure the levels of the mediators.

Results

The experimental group exhibited consistently higher OPG levels (p < 0.001), indicating that the topical injection of PRP had a notable effect on OPG levels and the associated regulatory mechanisms involved in bone remodeling. The RANKL mediator levels in the gingival fluid of orthodontic-treated teeth were increased over time in the experimental group, while the control group did not show any significant changes over time.

Conclusion

The topical injection of PRP demonstrated a significant influence on OPG and RANKL mediator levels, reaffirming its potential as a therapeutic approach for optimizing bone remodeling and enhancing treatment outcomes.

目的富血小板血浆（PRP）含有多种生物活性成分，包括生长因子。本研究旨在探讨局部PRP注射对正畸治疗犬龈沟液中骨保护素（OPG）和核因子κ b配体受体激活物（RANKL）介质水平的影响。方法选取6只10 ~ 12月龄成年公犬。每只狗随机分为实验组和对照组，一侧注射凝血酶- cacl2和PRP（实验组），另一侧注射凝血酶- cacl2和安慰剂（对照组）。在实验中，将一侧上颌象限作为实验组，另一侧上颌象限作为对照组。双侧拔除上颌第一前臼齿，然后在第二前臼齿和犬齿之间放置钛镍弹簧（200克）。实验组在第1、21和42天给予PRP和cacl2 -凝血酶的混合物，而对照组则给予cacl2 -凝血酶和安慰剂的混合物。在研究期间（第0、1、2、7、21、42、63天）定期采集龈沟液样本。采用RANKL和OPG酶联免疫吸附法测定培养基的水平。结果实验组的OPG水平持续升高（p < 0.001），表明局部注射PRP对OPG水平及其参与骨重塑的相关调控机制有显著影响。实验组正畸治疗后牙龈液中RANKL介质水平随时间升高，而对照组无明显变化。结论局部注射PRP对OPG和RANKL介质水平有显著影响，重申了其作为优化骨重塑和提高治疗效果的治疗方法的潜力。

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引用次数: 0

Recent advances in dental local anaesthesia 口腔局部麻醉的最新进展

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-09-01 Epub Date: 2025-08-20 DOI: 10.1016/j.adoms.2025.100575

Mohammed Inam Ullah Khan , Rabindra Pratap Singh , Jordan Prince , Amanda Vincci Chiu , Hassan El-Awour

Achieving profound local anaesthesia (LA) is a vital skill for oral surgeons, enabling efficient and successful completion of surgical procedures. Recent advances in LA administration aim to enhance patient comfort, improve clinician satisfaction, and increase anaesthetic efficacy.

This review examines the evidence on emerging techniques, including vibrotactile devices, computer-controlled local anaesthetic delivery (CCLAD), single-tooth anaesthesia, intraosseous injections, needleless systems, and buffered LA solutions, comparing them to conventional syringe techniques.

The evidence for these devices and techniques is mixed, with some trials reporting reduced pain or anxiety and increased speed of onset or anaesthesia success in teeth with pulpitis, while other trials report no significant differences compared to conventional syringes. Many of the trials had small sample sizes with high risk of bias, highlighting the need for large scale randomised controlled trials to better establish efficacy of these novel devices. Clinicians should weigh the available evidence alongside their own and patients’ preferences before considering new LA equipment. Emerging techniques hold promise but require further validation to ensure consistent and reliable outcomes in surgical practice.

实现深度局部麻醉（LA）是口腔外科医生的一项重要技能，可以有效和成功地完成外科手术。最近的进展是为了提高病人的舒适度，提高临床医生的满意度，提高麻醉效果。这篇综述检查了新兴技术的证据，包括振动触觉装置、计算机控制的局部麻醉输送（CCLAD）、单齿麻醉、骨内注射、无针系统和缓冲LA解决方案，并将它们与传统的注射器技术进行了比较。这些设备和技术的证据好坏参半，一些试验报告减少了牙髓炎牙齿的疼痛或焦虑，加快了发作或麻醉成功的速度，而其他试验报告与传统注射器相比没有显著差异。许多试验样本量小，偏倚风险高，强调需要进行大规模随机对照试验，以更好地确定这些新型设备的功效。在考虑新的LA设备之前，临床医生应该权衡现有的证据以及他们自己和患者的偏好。新兴技术有希望，但需要进一步验证，以确保在外科实践中一致和可靠的结果。

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引用次数: 0

Actinomycosis of upper lip: A rare case report 上唇放线菌病1例

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-09-01 Epub Date: 2025-07-26 DOI: 10.1016/j.adoms.2025.100566

Bander Y. Alkarri, Mohammed H. Albodbaij, Adam Ahmed M. AlQadhi, Mohammed A. AlQadhi

Actinomycosis is a chronic granulomatous infection caused by anaerobic Gram-positive bacteria, predominantly Actinomyces israelii. The cervicofacial region accounts for more than half of reported cases; however, involvement of the upper lip is extremely rare and often mimics benign tumors or mucoceles. In this case report, we describe a 41-year-old woman who presented with an 8-month history of a painless, slow-growing, mobile mass on the upper left labial mucosa. Diagnosis of an actinomycotic infection of the upper lip was achieved histologically, and the patient was treated with surgical excision and antibiotic therapy. Recovery was uneventful, and no recurrence was observed at 9 months follow-up. Our case highlights the importance of considering actinomycosis in the differential diagnosis of persistent lip nodules.

放线菌病是由厌氧革兰氏阳性细菌引起的慢性肉芽肿感染，主要是以色列放线菌。颈面区占报告病例的一半以上；然而，累及上唇极为罕见，通常表现为良性肿瘤或粘液囊肿。在这个病例报告中，我们描述了一位41岁的女性，她在8个月的历史中表现为左上唇粘膜无痛，生长缓慢，可移动的肿块。组织学诊断为上唇放线菌感染，患者接受手术切除和抗生素治疗。术后恢复平稳，随访9个月无复发。我们的病例强调了在鉴别诊断持续性唇结节时考虑放线菌病的重要性。

引用次数: 0

Platelet concentrates and arthrocentesis as therapeutic options for temporomandibular joint osteoarthritis: A systematic review of systematic reviews 血小板浓缩和关节穿刺作为颞下颌关节骨性关节炎的治疗选择：系统综述的系统综述

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-09-01 Epub Date: 2025-08-20 DOI: 10.1016/j.adoms.2025.100571

Faisal Alzahrani , Sally Issa , Akram Alshirah , Noha Seoudi

Temporomandibular joint osteoarthritis (TMJ OA) is a degenerative condition that leads to chronic pain and restricted jaw function, significantly reducing quality of life. Minimally invasive treatments such as platelet concentrate (PC) and arthrocentesis have emerged as promising therapeutic options. This systematic review of systematic reviews (SR of SRs) aimed to evaluate the effectiveness of intra-articular injection (IAI) of PC alone or in combination with arthrocentesis, compared to hyaluronic acid (HA), corticosteroids (CS), arthrocentesis alone, or placebo.

A comprehensive search of PubMed, Scopus, the Cochrane Library, and Google Scholar identified 18 systematic reviews and meta-analyses published between 2012 and 2024. Studies evaluating pain reduction and maximum mouth opening (MMO) were included. Methodological quality was assessed using the Critical Appraisal Skills Programme (CASP) and Risk of Bias in Systematic Reviews (ROBIS) tools.

PC, offer superior and sustained pain relief compared to HA, CS, and placebo, especially when combined with arthrocentesis. However, results regarding MMO improvement were inconsistent, likely due to variations in PC preparation, follow-up periods, and patient characteristics. Risk of bias analysis revealed 51 % low risk, 26 % high risk, and 22 % unclear risk, highlighting the need for more standardised high-quality research protocols.

PC show promising potential in managing pain associated with TMJ OA through a minimally invasive approach. Further research is needed to optimise protocols and confirm long-term therapeutic outcomes.

颞下颌关节骨性关节炎（tmjoa）是一种退行性疾病，导致慢性疼痛和颌骨功能受限，显著降低生活质量。微创治疗如血小板浓缩（PC）和关节穿刺已成为有前途的治疗选择。本系统评价的系统评价（SR of SRs）旨在评价与透明质酸（HA）、皮质类固醇（CS）、单独关节穿刺或安慰剂相比，单独关节内注射（IAI） PC或联合关节穿刺的有效性。对PubMed、Scopus、Cochrane图书馆和b谷歌Scholar进行了全面搜索，确定了2012年至2024年间发表的18篇系统综述和荟萃分析。包括评估疼痛减轻和最大张嘴（MMO）的研究。使用关键评估技能计划（CASP）和系统评价偏倚风险（ROBIS）工具评估方法学质量。与HA， CS和安慰剂相比，PC提供了更好的和持续的疼痛缓解，特别是当与关节穿刺联合使用时。然而，关于MMO改善的结果是不一致的，可能是由于PC准备、随访时间和患者特征的差异。偏倚风险分析显示低风险为51%，高风险为26%，不明确风险为22%，强调需要更多标准化的高质量研究方案。PC在通过微创入路治疗TMJ OA相关疼痛方面显示出良好的潜力。需要进一步的研究来优化方案并确认长期治疗结果。

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引用次数: 0

Spontaneous lower lip abscess in an immunocompetent individual 免疫正常个体自发性下唇脓肿

Advances in Oral and Maxillofacial Surgery

Pub Date : 2025-09-01 Epub Date: 2025-03-17 DOI: 10.1016/j.adoms.2025.100534

Prawash Sunuwar, Lakshmi Venkatakrishnan, Thomas Aldridge

An abscess is a localized collection of pus within tissue, often due to a bacterial infection. Lip abscesses are particularly rare, especially in immunocompetent individuals, as the lip is typically protected by keratinized mucosa and a good blood supply and lacks common sources of infection. Common causes of lip swelling include allergic reactions, trauma, and specific vascular or lymphatic malformations, such as haemangiomas and lymphangiomas. This article presents a rare case of a spontaneous lower lip abscess in an immunocompetent individual, discussing the clinical approach, surgical management, and a review of literature for insights into diagnostic and treatment challenges.

脓肿是组织内局部脓液的聚集，通常由细菌感染引起。唇脓肿特别罕见，特别是在免疫能力强的个体中，因为唇通常受到角化粘膜和良好血液供应的保护，缺乏常见的感染源。嘴唇肿胀的常见原因包括过敏反应、创伤和特定的血管或淋巴畸形，如血管瘤和淋巴管瘤。这篇文章提出了一个罕见的自发性下唇脓肿的病例在免疫正常的个体，讨论临床方法，手术管理，并回顾了文献的见解诊断和治疗的挑战。

引用次数: 0

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